Dr. Amol Soin: Non-Opioid Solutions to Pain Management | Exeleon Magazine

Dr. Amol Soin

Revolutionizing Pain Management

BBornandraisedinDayton,Ohio,Dr AmolSoin'sjourneyintothemedical ieldbeganaftercompletinghigh schoolinBeavercreek.Heembarked onachallengingbutrewardingpathat theUniversityofAkron,wherehewas partofacombined6-yearBS/MD medicalschoolprogram.

Hisearlyyearsweremarkedbya strongworkethicandakeeninterest inresearch,leadinghimtopublishthe book"CuringAmerica:ALookInside America'sFailingHealthCareSystem” whenhewas19.Thisworkhighlighted theplightofthe40millionAmericans (1997)withouthealthinsurance, despitethecountry'svasteconomic resources.

Dr.Soin'smedicaltrainingcontinuedat RushUniversityinChicago,wherehe specializedinanesthesiologyand furtherhonedhisresearchskills, particularlyinpainmanagement.His residencywasfollowedbyafellowship attheClevelandClinic,oneofthe UnitedStates'mostprestigiouspain managementdepartments.Here,Dr. Soinmasteredadvancedpain managementtechniquesand contributedtotheieldthrough researchandpublications

Overtheyears,Dr.Soinhasdeveloped numeroustechnologies–drugsaswell asmedicaldevices.Mostrecently,in 2022,hesoldSoinTherapeuticstoa publiclytradedcompanyonNASDAQ for$30million.“Itwassupercool becausewhenweclosedthedealthey announceditontimessquareinNYC ontheNASDAQbuilding,”herecalls.

SOIN NEUROSCIENCE AND SOIN BIOSCIENCE

Withavisiontoaddresstheopioid crisisinMontgomeryCounty Dr.Soin foundedtwocompanies:Soin NeuroscienceandSoinBioScience, biotechstartupsdedicatedto developingnon-opioidsolutionsfor painmanagement.

Witnessingthestaggeringstatisticsof addictionandoverdosedeaths,Dr Soinrealizedtheurgentneedfor alternativepainmanagement solutions."Istarteditafterrealizing peoplearedyingofopioidoverdoses becausewedon'thavegreat alternativestotreatpainwithout addiction,"herelects.Hismissionwas clear:todevelopbetter,non-addictive waystotreatpain.

Thecompany'snotableachievements includethedevelopmentofanovel typeofspinalcordstimulator(Soin Neuroscience)andagelpatch(Soin BioScience),bothinnovative approachestopainrelief.Thespinal cordstimulatorusescustomized electricalsignalstoblockpainsignals inthespinalcord,whilethegelpatch offersaconvenientandeffective methodfordeliveringpainmedication.

Dr.Soin'sworkhasnotonly contributedtotheadvancementof painmanagementbutalsoprovided hopeforcountlessindividuals sufferingfromchronicpain.

A PERSONAL EXPERIENCE

Dr.Soin'scommitmenttohismission isfurtherillustratedbyhispersonal clinicalexperiences.Onesuch experienceinvolvesTyrone,aformer collegeathletefromSouthwestOhio. Tyronesufferedfromaseverenerve disorderthatresultedin excruciatinglegpain,tothepoint wherehecouldn'teventouchhisleg. Afterenduringthispainfor20years, TyroneturnedtoDr.Soinforhelp.

UnderDr.Soin'scare,Tyrone receivedtreatmentwithSoin Neuroscience'snoveland experimentalspinalcordstimulator, whichdeliversacomplexwaveform toblockpainsignals.Theresults werenothingshortofmiraculous. "Wedeliveredourproprietary complexwaveformandhispain droppedto0,"Dr.Soinrecounts.The momentTyronecouldtouchhisleg fortheirsttimeinyearswas profoundlymoving,withhiswife breakingdownintearsoverthe phone.Thisstory,amongothers, underscorestheprofoundimpact thatDr.Soin'sworkcanhaveorhas hadonindividuals'lives.Thisshort youtubelinkshowsTyrone'sand othersstoryofpaindroppingto0 withthisnewdevice:

Talkingabouthiswork,innovations, andaccomplishments,he passionatelymentions“Thekeyisto alwaysputthepatient'sexperience irst.Ifyouspendallyourtimeand effortsfocusingonthat,thenyouare boundtodowell.”

SPINAL CORD STIMULATOR: A CUSTOMIZED APPROACH TO PAIN RELIEF

InventedbyDrAmolSoinandDr EricSchepis,SoinNeuroscience's newspinalcordstimulatorisa marvelintheieldofpain management.Itoperatesthrougha surgicallyinsertedleadplaced directlyonthespinalcord, equippedwithmultipleelectrodes thattransmitelectricalsignalsto blockpainsignals.Thisprocess, knownasneuromodulation,alters theiringofpainsignals,offering patientssigniicantrelief.

Whattrulydistinguishesthisdevice isitsapproachtosignaling. Traditionalspinalcordstimulators emitbasicsignals,akintoblipsor beeps.Incontrast,Soin Neurosciencehaspioneeredtheuse ofcomplexelectricalsignals,akinto deliveringharmonioussymphonies tothenerves.Thisinnovative approachwasinspiredbythe realizationthatcertainsounds, muchlikemusicalcompositions, aremorepleasingthanothers.By convertingspinalcordstimulation signalsintoaformofnoise,the teamatSoinNeurosciencehasbeen abletoidentifyanddeliversignals thatarenotonlyeffectivebutalso moreagreeabletothepatient

Oneofthemostgroundbreaking aspectsofthistechnologyistheuse ofafrequencyofenergythatechoes througheveryatomintheuniverse, knownasthe"primordialsoundof theuniverse."Thisfrequency, believedtobesigniicantinthe creationevent hasshown remarkableresultsinmakingpain virtuallydisappearwhenappliedto thespinalcord.

Dr.Soinhassharedinsightsinto thistechnologythroughaconcise two-minutevideoonYouTube, whichprovidesahelpfuloverview ofhowthespinalcordstimulator worksandtheprinciplesbehindits success:YouTubeVideo:Spinal CordStimulator

Byharnessingcomplexelectrical signalsandcraftingcustomized tunedsignalsspeciicanduniqueto eachpatient,SoinNeuroscienceis notonlyadvancingtheieldofpain managementbutalsoofferinghope tocountlessindividualssuffering fromchronicpain.

GEL PATCH: A DISCREET AND VERSATILE PAIN SOLUTION

Inadditiontothespinalcord stimulator,SoinBioSciencehas developedthe"gelpatch,"aunique painreliefsolutionthatapplieslike agelanddriesclearandfunctions likeapainpatch.Unliketraditional topicalmedications,thegelpatchis water-resistantandcan continuouslydelivermedicationfor 6-8hours.Itsinnovative formulationallowsfortargeted application,makingitidealfor treatingavarietyofpains,including jointpain,arthritis,andbackpain.

TheseproductsdemonstrateSoin BioScience'scommitmentto developingnon-opioidpainrelief optionsthatarebotheffectiveand patientfriendly Byfocusingon personalizedtreatmentand innovativedeliverymethods,the companyismakingsigniicant stridesinimprovingthequalityof lifeforthosesufferingfromchronic pain.

NAVIGATING THE CHALLENGES OF THE BIOTECH INDUSTRY

Dr.AmolSoinisacutelyawareof thehurdlesfacedbythebiotech industry particularlyintherealm ofpainmanagementandmedical innovation.Heoutlinesseveralkey challengesthatimpactthe developmentandadoptionofnew medicaltechnologies.

• Price Controls: Heexpresses concernaboutpotentialprice controlsonpharmaceuticals, whichcouldlimittheinancial upsidefornewinnovations. "Thismayhavedownward pressureoninnovation,"he explains,emphasizingthehigh costsofdevelopmentandthe riskofnotbeingabletorecoup thoseexpenses.

• Regulatory Hurdles: TheFDA approvalprocessisanother signiicantbarrier characterizedbyitsexpense andtime-consumingnature.Dr. Soinhighlightsthenecessityof rigorousstudiesforpatient safetybutacknowledgesthe challengestheypresentfor gettingproductstomarket

• Complexity of Clinical Trials: Pain,beingasubjective symptom,addsanotherlayerof complexitytoclinicaltrials.Dr. Soinnotestherelianceon patient-reportedoutcomes, whichcanbemorechallenging toquantifyandvalidate comparedtoobjective measures.

• David vs. Goliath: The dominanceoflarge multinationalcorporationsin thebiotechindustrypresentsa dauntingchallengeforstartups likeSoinNeuroscienceandSoin BioSceince.The

transformationalleaderarticulatesthethreat ofbeingovershadowedorcrushedbythese giants,especiallyiftheirproductsposea disruptivethreat.

• Insurance Companies: Finally,hepointsout thereluctanceofinsurancecompaniesto covernew,potentiallysuperiortreatments duetocostconsiderations.Hecriticizesthe preferenceforcoveringcheaper,narcotic painkillersdespitetheiraddictivenatureand lackofeficacyinaddressingtherootcauseof pain.

Throughhisinsights,Dr Soinshedslightonthe multifacetedchallengesthatinnovatorsinthe biotechindustryface,emphasizingtheneedfora supportiveecosystemthatfostersinnovationand patient-centricsolutions.

LEAVING A LASTING LEGACY

Dr.Soin'scommitmenttoinnovationandpatient careextendsbeyondhisclinicalpractice.Hehas servedinvariousleadershiproles,includingas PresidentoftheAmericanSocietyof InterventionalPainPhysicians,TheOhioSocietyof InterventionalPainPhysiciansandtheState MedicalBoardofOhio.Hiscontributionstothe ieldhavebeenrecognizedthroughmultiple awards,includingbeingnamedoneofAmerica's TopDoctorsinPainManagementandreceivingthe Patient'sChoiceAward(OhioPainClinic)

Today,Dr Soincontinuestoleadthewayinpain managementasthemedicaldirectoroftheOhio PainClinic.Hisworknotonlyaddressesthe immediateneedsofpatientsbutalsocontributes tothebroadereffortstocombatopioidaddiction andimprovehealthcareaccessibilityintheUnited States.

Talkingabouthisvisiongoingforward,Dr Soin concludessaying“Iamexcitedtocontinue bringing-innewinnovativetechnologiestothe market.”

EXELEON SHORTS

One Book Entrepreneurs must read –SurvivetoThrive:JourneyofDr.RajeshSoin byVinitK.Bansal.

One Quote that Motivates you the most –“Keepagreentreeinyourheartandperhaps asongbirdwillcome.”Chineseproverb

One Advice for Emerging Doctors –Tryto maintainyourautonomy.Inthedaysof corporatehealthcare,privateequitybuying upmedicalpractices,andphysiciansworking

forlargeentities,itisimportanttostay focusedonyourpatientasyour“bosses”will focusoninancialsandproits.Youneedto alwaysputthepatientexperienceirst

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