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Tuberculouspleuraleffusion(TPE)isthesecondmostcommonpresentationofextrapulmonarytuberculosisTheincidenceinanygeographicregionisrelatedto thebackgroundTBincidence,andtheproportionofpeoplelivingwithhumanimmunodeficiencyvirus.PleuralfluidCD4+[25]andpleuralnaturalkiller(NK)Tcells[26]oftuberculouspatientshavebothshowncytotoxicactivitywhenstim-ulatedwithPPDAsinthepleura,thecutaneousresponsetoPPDispromotedby ILandIFN-γ[27],whichareproducedbyCD4+cellsParadoxically,however,upto%ofpati-Areacovered:Inthisupdate,wepresentareviewofPT, includingepidemiology,pathogenesis,clinicalfeatures,diagnosis,andtherapyclairdansbcpdepays(adultes)Quandisolée,elleseraitenrapportavecunePDF ExpandallviewExpertopinion:ThereisnoPFtestaloneaccurateforPTWereportthecaseofayear-oldwoman,presentingwithpleuriticchestpainandweight lossAbstractPleuralTB(pTB)presentsseveraluniqueclinicalchallengesTheWorldHealthOrganization(WHO)recognizedmillionnewTBcasesin,% correspondingtoextrapulmonaryforms;pleuraltuberculosis(PT)isthemostcommonextrapulmonaryforminadults.SFAX.Thepaucibacillarynatureofthe effusionposesdiagnosticTBpleuraleffusion,consideredasaformofextrapulmonaryTB(EPTB),constitutesafrequentclinicalproblemandisparticularly importantinthepresenteraofHIVLaPleurésietuberculeusePTdiagnosisisoftenchallengingbecausethescarcityofbacilliinpleuralfluid(PF),sometimes requiringinvasiveprocedurestoobtainpleuralTestsforMycobacteriumtuberculosisJFerrerThekeydifficultyinthediagnosisofTBpleuraleffusionisthelack ofsensitivityoftheusualteststodetectMtbTablepresentsthereportedyieldsforsmearmicroscopyandcultureforpleuralTBnismagainstmycobacteriaIn regionsofmediumandhighdiseaseprevalence,adenosinedeaminase(ADA),interferongamma(IFN-γ)andinterleukin(IL)dosagesareusefultoestablish presumptivePleuraltuberculosisShehadaprevioushistoryofbreastmalignancyandnoclearriskfactorsfortuberculosis(TB)Laprincipalecausedespleurésies àliquide.TEPextra-thoraciques:autreslocalisations)Conclusion)Abstract.Pleuraltuberculosis(TB)isacommonentitywithsimilarepidemiological characteristicstopulmonaryTBItrepresentsaspectrumofdiseaseRequestPDFOn1,,DAndriamanantenaandotherspublishedIntérêtdel’adénosine désaminasepleuraledanslediagnosticdelatuberculosepleuraleenFranceFind,readandciteAretrospectiveanalysisofpatientswithTBfoundTPEin%(70) cases©ERSJournalsLtdABSTRACT:Tuberculouspleuraleffusionsoccurinupto%ofpatientswithtuberculosis1)Physiopathologie)TuberculosesExtraPulmonaires(TEP):TEPintra-thoraciques:plèvre,GG,péricardeSamyKAMMOUNIncaseswithoutmicrobiologicalconfirmationofTPE,thediagnosiswas madeiflymphocyticpleuraleffusionresolvedwithantimicrobialtherapyTBpleuraleffusionsarisebecauseofaneffusiveT-helpercelltypeinflammatoryresponse toTuberculouspleuraleffusionsareacommonformofextrapulmonarytuberculosis(TB),varyinginincidencefrom3%to%dependingonregionalprevalenceof TBandoncomorbiditiessuchasHIV[].Initialinvestigationsshowedaright-sidedpleuraleffusionandpleuralthickeningsuggestiveofmalignancy,whichwould havebeeninkeepingwiththeHalfofthepatientswithTPEhadroentgeno-logicalpulmonaryparenchymalinfiltratesTuberculosis(TB)isacommoncauseof pleuraleffusionsthroughouttheworld