OIE was r0prosent0d by Prof. F. Lucam 9 Dr. G. Moosbrugger and Dr. R. Willems. Th0 Commission v,as represented by Dr. I.A. Gallo·imy, Dr. H.S. Frenkel and Dr. E. Fogedby. The problem was thoroughly dis cussed and it ryas felt by tho majority of the group that the subject should be approached at a high scientific level. Tho group, thoroforo; made the following proposals g.- the v,hole experiment should be carried out at ono centre; a comparative tost between a "culture" virus vaccine and a "natural" virus vaccine should be carried out; only one type of virus vaccine should be investigated at a time; the number of' animals in the experiment should bo increased from that originally suggested; in order to minimize the risks of infection and so that suitable animals might be readily provided and maintained, tho experi ment should be carried out at tho Research Virus Institute, Pirbright; Dr. Frenkel be roquosted to prepare two monovalent vaccines for tho purpose of tho oxporiment (a "culture" virus vaccine and a "nature.l" virus vaccine); tho viruses used for these vaccines should be titratod at tho Pirbright Instituto and each of tho vaccines should contain th,, same quantity of antigen� tho immunity produced by each vaccine should bo challongod at throe, six, nine and tvrnlvo months after vac cination, ten vaccinated together with 2-4 control animals being used at each challenge; that 184-192 cattle be provided for tho oxporimont. Tho group also considered tho approximate costs of the oxporimont and came to tho following conclusionsgPurchase of animals .••.•••••..•••£ Feeding and maintenance of ani ma1 s . • . • £ Ex:penses of exports••••··•······•£ Incidentals •·••··•·····•···•···••£ a , • • • o , o • • • • " • o " • o • •
Total
10 9 000
($ 28,000)
7,500 1,500 1,000
( $ 21, ooo l ( $ 4,200 ($ 2,800
£ 20,000
$ 56,000)
It is oxpocted that information on tho financing of tho suggested experiment ·,7ill be available at tho Fourth Session of tho Commission. f.'oot-o.nd-I.Io-1:!ih DiG-On.o·o in L\tropoan Countries The disease position in Europe has boon kept under review since tho last Session of tho Commission and reports have boon made by tho Secretariat to tho Executive Committee. In addition to visits made by tho Secretariat to different countries, tho Executive Committoo received verbal reports from tho Directors of Veterinary Services of Belgium, tho Gorman Federal Republic and Switzerland at a recent moot ing. During 1956, tho Socrotariat visited Portugal, Spain, tho Nether lands, Franco, Switzerland, Denmark and tho United States of America. Early in 1957 short visits �oro also made to tho Gorman Federal Republic, the Netherlands, Belgium, Franco and Austria in connection v,ith tho increase in tho incidence of foot-and-mouth disease in Europe, In Portugal, foot-and-mouth disease has occurred fairly froquently in tho past, invasion, as a general rule, having takon place from Spain.