Issuu

Meeting Report No. 1957/5

REPORT of tho FOUl-t'l'H 8:GSSiuN OF 'l1 HE EUROP:SAN CO:M:M:ISSION FOR T113 CONTROL OF FOOT-AND-MOUTH :DISEASE

held in Rome, Italy 2 and 3 April 1957

FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS Rome� Italy April 1957

FA0/57/4/2671

CONTENTS INTRODUCTION

. . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Pago 1

Adoption of the Agenda•••·•••••••·····••·•·········•··•

Election of Officers ......... , .............. , . . . .. . . . . ..

PARTICIPATION IN THE MEETING •••• •. .•• .•• ••••• . ••• ••• .•••• •• •

D c1 0gat ions .

Ill • • • • • • • •

• • , • • • • • • • • • • • • • • • • • • •

• • • " • • • • • • • •

Observers from Countries •·•·•·•••·••·••·····•··•·•·· .••

Observers from Intornntional Organizations ·••·••··•·•••

FAO Staff

Officers of tho Mooting•••••·•·••···•·••·••·········•·•

SUMMARY OF DISCUSSIONS • , •••.••.••••••.• ,••...•.••. ,... , .•. ••

Report on Activities since tho Third Session···••••••••

Tho Virus Research Institute, Pirbright, United KingdoQ, as a Central Roferoncc L�boratory •••••• Mutation of tho Virus of Foot-and-Mouth Disease

. . ..

Duration of Immunity follo..-,ing Vaccination against Foot-and-Mouth Disease•••·••··••·•••·••• Foot-and-Mouth Disease in European Countries

......

8 9

Visits to Different· C · ountries by Members of the Secretariat·••·•·•·••·············•·•··••··• Visit to Belgium by Joint OIE/Co□mission Group

....

11 12

Cornrnission ........•...•..•.••...•.•......•. , . . . •

Budget and Accounts ,•• ,• ,• •• ••• • . .. •• •.•• • •• •. •• •..• •• •

Future Activities of the CoQ@ission ·•••••••···••·····••

Proposal to amend tho Constitution of the

- ii Pago Report of tho Standing Technical Cor.rrnittoo •••••.••.•• Overall Plan for tho Control of Foot-and-Mouth TuropG

········••o••·oo••OO•o•••o••·

Supply of Vaccines ••.•••.••.••.•••..•••..•••. , • •

Recent Progress in Virus Cultivation ····•••····•

Anondnont to tho Constitution of tho Commission • • ••• •

Application from tho Govornncmt of Grecco to join tho Commission . .

Dison.so

Any other Business

•

1,)

•

APPENDIX I Budgets for 1957 and 1958

••••••o•••••••oo••••••••••••

.........

APPENDIX II Accounts for the Yoar ended 31 Docor.1bor 1956

INTRODUCTION The Fourth Session of the Cor.imission was hold in Rome on 2 and 3 April 1957. In opening the mc:.:,ting, Dr. J,M, van den Born, Vice-Chairman, explained that the Chairman ' ..1.s unable to attend the mooting. Dr. Ralph 1.Y. Phillips, Acting Tiiroctor, :Jivision of Agriculture of the Food and Agricul�ur0 Organization of tho United Nations, addross0d the meeting. Dr. Phillips ext,mded a W8lcomo to the delegates and obsJrvcrs on behalf of the Director-General and revie,v::H� tho pro£-ress since tho 'l'hird Session. Ho referred to tho iiri:;ontion of tho Govornmont of Belgium to adhoro to tho Commission and said that nogotiations woro in progress with the Govornmcmt of Groec,). Reference was also made to tho work of tho Commission as an example of a regional activity and of tho benefits which could follow. Adoption of the A�n3_B:, Tho Commission adoptod tho agenda which had boon circulat0d by the Secretariat 9 with tho addition of an item in connection with a report of tho Standing Tochnical Committee. 1loction of Officors On the motion of tho delegation of Yugoslavia, socondod by tho delegation of Norway 9 J.C. Nagle was ,)loct:id Chairman until tho noxt session of tho Commission, J.M. van don Born and S. Mihajlovic woro oloctod Vic�-Chairmen on tho motion of tho delegation of Ireland, seconded by tho delegation of Austria. To fill tho throo remaining vacancies on tho �xocmtivo Committee'� the follov,ing woro electediMessrs. I. Altara, Italy; United Kingdom.

F/10/57 /4/2671

A.::J. Pranga o Sj.lva� Portugal;;

J.N. Ritchie,

PARTICIPA'I1ION IN THE MID:C'rING J)ologations Austria

nr. Michaol Vogler Fndc:t:-1,l Minis-try of Agricultui>::1 and Fores tr;_Vicnna2 I J:..·. 1.'lilhulm Grausgrubor rudoral Institute for Virus Research :Jot z.ondorf Vionna 2 XII

Denmark

Dr. F. W,¢ldike Nielson DirJctor of Votcrina�y Services Nyropsgado ? 37 Coponhar:.:911 Dr. E. Michelson Acting Dir,:ctor Stat□ Votorinary Instituto for Virus Rosoarch Lindholm pr. Kalvohavc

Ireland

Mr. P.H. Rogan Diractor of Veterinary Services Dublin

Italy

Dr. A. Adornollo General Votorinary Inspector Veterinary Sorvicos Piazza Dalmazia, 1 Romo Professor TI. Ubertini Diructor Ins ti tuL· for Animal Disease Control in Lombardy Via Cromona� 282 J3roscia

3 Neth:.-rlands

J)r. J.M. van clon :Born J)iroctor of Votorinary Sorvicos Prins Mauritslaan, 99 Tho Hague J)r. H.S. Frenkel J)iroctor State Ins ti tuto for Vot�rcina:ry Research "" Amstor dam

Norway

Mr. llol go �' 1.ggorud Assistant Director Vot�rinary Diroctorato Royal Ministry of Agriculture Oslo

Portugal

Dr. A.Z. Fran9a e Silva Diroctor General of VotorinQry Services R. Victor Cordon 9 4-3 ° Lisbon

Turkey

Mr. Kadri Esor J)ir0ctor General Votjrinary Services Ministry of Agriculture Ankara Mr. Farulc. Barim Chief Animal Disoaso Control Department Ministry of Agrioulturo Ankara Mr. F�anois A. Ralston Livost"ock Advisor (USOM) Ministry of Agriculture Ankara

United Kingdom

Mr. J.N. Ritchie Chief Vot .rinary Officor Ministry o...:' Agriculture, Fisheries and Food Animal H0alth Division Hook Riso Tolworth, Surbiton Surrey Dr. I.A. Galloway Director Resoa:,:·ch Ins tituto (Animal Virus Disoa.cos) Pirbright, Surrey

4 Mr. Ahmed Orhan Acting Chief VetJrinary Officer Votorinary Sorvico Nicosia� C�,:prus

Yugo a lavia

Dr. Sava Mihajlovic Diroctor Fod.L."al Voto:: i;.,.::i,ry Sorvicos Savska 35/�Bolgrado Dr. iiarko �,Iisa;ilovic J)iroctor Veterinary Institute Put Ivana Uilutinovi6a, 123 Subotica r/Ir. V. Ilic Socr.:;t:..ry F;Jdornl Vot::,rina:cy Sorvicos Su.vska 35/v Bolgl'ado

Obsorvcrs from Countri8s Belgium

Dr. Joan-Pierro Lattour Inspector of Veterinary Services Ministry of Agriculture Brussels

France

Professor R. Vuillawno Chief of Veterinary Services Ministry of Agriculture 78, rue do Varenno Paris2 ( 7.£2.

Gorman Fodoral Republic

J)r, K. Buhl Diroctor of Vctorinary Services Ministry oi A�riculturc Bonn

Groece

Mr. P. Lovordos Royal Greek �mbassy Via G. Rossini, 2 Romo

Spain

Ing. Agr, G. Dscard6 Agricultural At"cache Spo,nish Embassy Via Lima, 23 Romo

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5 Swodon

Mr. Claes Konig First Socrotary Royal Swedish Dmbassy Romo

Uni ted Stat0s of America

Dr. P.D. DoLuy Chio±' ) :foro:poan Mission for Re:r::oarch on F oot--and-1Ji:outh Disuasu Victori,1 Ho J : )1 J,,_r,1[: torda,m

Obsurvors from International Organiz�tious International Offico of Epizootics

Professor G. Flilckigur Director F'odoral Votorinary Services Viktoriastrasse, 85 Berno

European Confederation of Agriculturo

Dr. Loris Carrori Corso Vitt. Emanuele, 101 Romo

.E.Prmanent Committee for tho International Veterinary Congresses

Dr. G, Boldrini Vet0rinary Officer Veterinary Services Piazza Dalmazia, 1 �

FAO Staff Dr. Ralph W. Phillips Acting Director Agriculturo Division FAO, _B.ome Sir Thomas Dalling European Commission for tho Control of Foot-, .1d...:Mouth Disease Animc.l Production Branch Agriculture Division Fil.0 9 Romo Dr. ErjJ<.: Fogodby Europoan Commission for tho Control of Foot-and-Mouth Disease Animal Production Branch l\.griculturo Division FAO, Romo Dr. K.V.L. Kesteven Chief, Anir.1al Production 13:c-=i,nch itgriculturo Division FAO, Romo

Officers of tho Mooting

J.M. van don Born� Chairman S. Mihajlovic, Vico-Chairman Sir TLomas Dalling, Socrat_riat

c::rnvIMARY OF' DISCUSSIONS Roport on Activitios since the Third So8sion Tho J�xocutivo Committeo roport0d as followc: Sincu tho Third Session of tho Cormnission, the Exocutivo Committee has mot on throe occasions, viz. in Yugoslavia, Ireland and tho Noth,;r lo,nds: tho moetihg in Ireland was hold in January '19.57 b::icauso of tho throat of the spread of foot-and-mouth disoaso in aricl into diffo:ront European countries and to consider a request from tho Government of Austria \ for assistance in controlling an invasion of tho disoaso. . . .. . At those mootings tho SocrotJ.riat of tho Commission made roports on tho work carried out during tho procoding.pcriods end decisions woro taken on further activities. Tho Virus Rosoarch Instituto 2 Pirbright 2 Unitod Kingdom2 as a Contr;il Roforcnco Laboratory At its Third Sossion tho Commission d.ociclod 11 thr,,t a formal appi0 0;:i.ch be made to tho appropr·L:i.t;J authoritics in tho United Kingdom with a vj_o,1 to tho designation of tho Virus Ilosoarch Institute, Pil0bright, U.K., as a roforonce laboratory for virus typ0:::i, to maintain all tho strains of virus and typo-specific anti-sora, to label V.J,riant strains within types and to confi rm typing of viruses on request from eountrios". In connoction vvith tho Yrork cnvisagod at tho Central Roforonco Laboratory it would b,:; mado cloar to all countries ;:mil intorna. .ional organizations concerned that r)gular typing of fiuld samples from the different countries would. romain tho countries' ovm rosponsibility. Tho Reforonc0 Laboratory vrould, hovrnvor, givo as::;istc:,nco ,,-,hon difficulties in typing arose and might wish, from time to timo� to obk.in fiold. srunplos of virus and sorum from different countries.

- 7 The Food and Agriculture Organization, because of its interest in the control of foot-and-mouth disease throughout the world felt that the activities of a Central Reference Laboratory should not be con fined to European countries but should include all countries in which foot-and-mouth disease occurs. The Pirbright Institute is already in touch with many countries throughout the world. The European Commission must also interest itself in the disease and the types of virus which are present in countries outside Europe. While only the three classical strains of the virus have been demon strated in outbreaks of foot-and-mouth disease in Europe and in the Americas, from tho work at the Pirbright Institute throe further immunological typos have been shown to exist in Africa and, more recently, another type has been recovered from some parts of Asia, These findings have important implications for tho work of the Commis sion for it may happen one day that Europe may be invaded with one or several of those exotic typos. Thus, it is of considerable importance that information may be available on all typos of tho virus throughout the world. Since the Third Session of tho Commission oorrespondenoo and dis cussions havo taken place with some of the United Kingdom authorities and it is hoped that a further statement on this subjoct will be made at tho Fourth Session of the Commission. liutation of tho Viruo of Foot-c.nd-:�10U-t-h Disease Since it was shown in the 1920s that there existed three distinct immunological types of foot-and-mouth disease virus in Europa, tho question of mutation from ono typo to another has often boen tho sub ject of discussion. Recently, further consideration has boon given to tho possibility because of the oxpcrionce during tho foot-and-mouth disease outbreaks in Switzorlan4 in May-July 1956, Professor Fluckigcr presented a report to tho Commission's Executive Committee in Soptombor 1956 and this has subsequently been published (Bull. off. intornat. des Epizootios, 1956, Vol. XLV� pp.707-716). Following this report, tho Executive Committee decided that a Committee composed of roprosontatives of tho Commission and of tho Office International dos Epizootios bo set up to discuss tho subject and, if thought necessary and desirable, to suggest and initiate research work on it. With the concurrence of OIE, this Committee was formed and mot at the Office of tho OIE on 8 November 1956. The OIE was ropresentod by Dr. G, Ramon, Dr. A. Merlo, Dr. R. Vittoz, Dr. E. Mathieu, Prof. F. Lucam and Prof. G. Fluckigcr: the representatives of tho Com mission were Dr. H.S. Frenkel, Dr. I.A. Gallo�ay, Sir Thomas Dalling and Dr. E. Fogedby. The findings and decisions of the Committee may bo summarized as follows:- Mutation of tho virus of foot-and-mouth disease may be defined as a complete change from one distinct immunological type to

another. Thus, variation within a ty:pe cannot be considered as truo mutation. While it is generally believed that mutations havo taken place in tho field on some rare occasions, the whole question of mutation of tho virus of foot-and-mouth disease has so far not boon scientifically provedg in fact, very littlo is knovm about such mutation. On the other hand, it is knom1 that strains of tho virus of recognized and proved immunological typos have been kept for many years in laboratories and have maintained their typo specificity, The Swiss exporienco led to tho suggestion that typo C virus had mutated to typo O and that this typo O virus had mutated to typo A, all within a short space of -time. It vms agrood that if this wore so, it must be quite exceptional. Tho Committee felt that it would be very difficult to plan any ,research which would domonstrato mutation experimentally and that it would be bettor that the different laboratories work on the subject. If any observations of value emerged from such work, consideration might bo given to a further mooting of this Committee, Dura.tin� of L"J::::1up.ity follo·,--;h-i..� Vo.ccinntio�n nga.in::::t Foct-a.r.J.-lfouth Disease At different sessions of tho Commission, discnnmiuno lravu �o.lr�n place on tho carrying out of experiments to demonstrate the duration of immunity following vaccination against foot-and-mouth disoa.so. Sovoral plans for such oxperimonts havo b0on drawn up. Thus in 1956 an oxporimont ';,ras discussed. and somo details -,-rnre produced in vvhich groups of cattle in throe difforont European countries would be vac cinated with a trivalent culture virus vaccine and challenged at different intervals. It vras hoped that tho three countries concerned ·,-,,rould boar somo of tho costs of tho experiment and that some financial support vvould also be forthcoming from international organizations. This type of oxporimont Yms suggested bocauso tho Italian Veterinary Authorities have strossed that thore is not yet enough information on tho value of culture. virus vaccine nnd that more experimental vvark should be carried out. On further discussion at an informal mooting of somo members of the Commission's Standing Technical Committee in Paris in May 1956 ? it was agreed that an experimont using a considerable number of cattle should be undertaken at tho Virus Research Institute, Pirbrightg but, as tho results of such an oxporimont would not be available for some con!lidorablo time, it ,;ms further agreed that smallor-ecale experi ment� should also bo carried out at institutes in different countries in order that information could be accumulated, Tho latter oxporimonts would. follow tho design referred to in the above paragraph. In ardor to como to a final decision on tho design and nature of tho experiments a group of workers on foot-and-mouth disease, roproscm ting tho Commission and OIE, mot in Paris on 3-4 December 1956. Tho

OIE was r0prosent0d by Prof. F. Lucam 9 Dr. G. Moosbrugger and Dr. R. Willems. Th0 Commission v,as represented by Dr. I.A. Gallo·imy, Dr. H.S. Frenkel and Dr. E. Fogedby. The problem was thoroughly dis cussed and it ryas felt by tho majority of the group that the subject should be approached at a high scientific level. Tho group, thoroforo; made the following proposals g.- the v,hole experiment should be carried out at ono centre; a comparative tost between a "culture" virus vaccine and a "natural" virus vaccine should be carried out; only one type of virus vaccine should be investigated at a time; the number of' animals in the experiment should bo increased from that originally suggested; in order to minimize the risks of infection and so that suitable animals might be readily provided and maintained, tho experi ment should be carried out at tho Research Virus Institute, Pirbright; Dr. Frenkel be roquosted to prepare two monovalent vaccines for tho purpose of tho oxporiment (a "culture" virus vaccine and a "nature.l" virus vaccine); tho viruses used for these vaccines should be titratod at tho Pirbright Instituto and each of tho vaccines should contain th,, same quantity of antigen� tho immunity produced by each vaccine should bo challongod at throe, six, nine and tvrnlvo months after vac cination, ten vaccinated together with 2-4 control animals being used at each challenge; that 184-192 cattle be provided for tho oxporimont. Tho group also considered tho approximate costs of the oxporimont and came to tho following conclusionsgPurchase of animals .••.•••••..•••£ Feeding and maintenance of ani ma1 s . • . • £ Ex:penses of exports••••··•······•£ Incidentals •·••··•·····•···•···••£ a , • • • o , o • • • • " • o " • o • •

Total

10 9 000

($ 28,000)

7,500 1,500 1,000

( $ 21, ooo l ( $ 4,200 ($ 2,800

£ 20,000

$ 56,000)

It is oxpocted that information on tho financing of tho suggested experiment ·,7ill be available at tho Fourth Session of tho Commission. f.'oot-o.nd-I.Io-1:!ih DiG-On.o·o in L\tropoan Countries The disease position in Europe has boon kept under review since tho last Session of tho Commission and reports have boon made by tho Secretariat to tho Executive Committee. In addition to visits made by tho Secretariat to different countries, tho Executive Committoo received verbal reports from tho Directors of Veterinary Services of Belgium, tho Gorman Federal Republic and Switzerland at a recent moot ing. During 1956, tho Socrotariat visited Portugal, Spain, tho Nether lands, Franco, Switzerland, Denmark and tho United States of America. Early in 1957 short visits �oro also made to tho Gorman Federal Republic, the Netherlands, Belgium, Franco and Austria in connection v,ith tho increase in tho incidence of foot-and-mouth disease in Europe, In Portugal, foot-and-mouth disease has occurred fairly froquently in tho past, invasion, as a general rule, having takon place from Spain.

- 10 -

On tho other ha.nd, some frozen moat is imported from South American countries, especially Brazil, and constitutes a further potonticl source of infection. Tho overall position in Portugal is not con sidorod to bo serious and outbreaks aro usually mild in character and tho disoaso has shovm a. tcmdoncy to die out. Bocauso of the risk of introducing exotic typos of foot-and-mouth disease virus, ospocially tho African typos, tho importation of cattle into Portugal from AngolA, has boon discontinued. Foot-and-e10uth disease opizootics in Spain aro, as a gon0ral rulo, caused by invasion of tho disease from Franco. At tho beginning of 1956 tho diseaso flared up and caused a number of outbreaks but, although opizootics in Spain have of ton boon sovoro, YJith considerable economic loss, tho 1956 outbreaks vrnro of a mildor cha.ractcr.

In tho Netherlands, only 47 outbreaks occurred during 1956. A systematic vaccination prograra has boon followed a.nd, combined rlith tho slaughter of affoctod animals (usually pigs and unvaccinatcd young stock), has maintained a remarkably satisfa.o-tory disoaso position. A policy of slaught or of 2.ffoct cd animals has boon mado. possible because of tho results of □ass vaccination, In Switz or land, aft or the outbreaks in May-July 1956 n:ttri hut.�.hl r: to pigs in transit from Belgium to Italy r.'oro brought under control, only sporadic outbreaks have b0on reported. Tho Swiss system of controlling foot-and-mouth disoaso (combination of slaughter, vaccina tion, disinfection and ::1ovomont control) continues to gi vo good results.

In Belgium, tho uso of trivalent vaccine is being extensively practised. Tho vaccine consists of culture virus of O and C typos and natural virus of A type. Thero is clear ovidonco that this vaccine confers a considor.1blo dogroo of immunity>. 1:1ost of tho outbreaks v,hich are recorded occur anong pigs •,·vhich are not vaccinated, or in young, unvaccinatod co:ttle. Vaccination is being encouraged. Observations in Belgium indicate that� although tho vaocina.tion of pigs may bo followed by an irnmuni ty of short duration, tho poriod of pro tection may be of considorablo value in preventing spread of tho infection, In tho Gorman Federal Republic, vaccination is being practised and is giving satisfactory rooults. Vaccination hc1s boon usod along frontiers throatenod by invasion and in localized outbreaks to prevent spread of tho disease. Slaughter of affected animals has been carried out in a proportion of outbreaks but is consid0rod to ·bo impractical in largo herds, Tho prosont position of foot-and-mouth disease in tho Gorman Fodoral Republic would appoar to be well in hand. In Denmark, only few outbreaks have boon rocontly recorded, Vaccination is proceeding in tho southern part of tho country Yrhoro it is appreciated that tho method of control usod in Germany has provontod tho usual mass infection.

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In tho Unit0d Kingdor:i, there -,,ere many introductions of foot-and mouth disease virus in 1956. Satisfactory control has been exorcised by the usuaJ. stamping-out policy ·irith all it involv0s by way of slaughter of stock, mover.ient control, disinfection of premises, general sanitary 1i1easures, etc. On circuostantial GVidGnce, sources of infec tion are fro□ ioported South Ar.ierican r,rnat and by indirect means including birds fro□ continental Europe. All restrictions had boon removed by tho end of F0bruary 1957 and th0 country ·;ms once r.1oro froo froc foot-and-mouth disease. In Italy tho disease position is probably unaltered, In Franco there is apparently no improvooont in the recent posi tion. It is unde.rstood that consideration is being givon to tho adoption of a slaughter policy for a particular region and that there arc efforts to oncourago further vaccination. There appear, hoYrevor, to be insufficient supplies of vaccine and, even if adequate, thoro aro too few veterinarians to undertake an effective vaccina.tion progran. Norway, Sweden, Iceland, Finland and Ireland continue to bo free froi:1 tho disease. Yugoslavia remains free from foot-and-□outh disease and so far as information is available, tho position in Eastern Europe continues to be satisfactory. In Greece 9 sor;1e few outbree.ks occurred during 1956g inforraation is that tho position is now satisfactory.

tho latest

Austria, after a long period of freedom, became infeotod in D0cer.1ber 1956, close to tho Bavarian border. After tho r;.iddlo of January whon 42 outbreaks wore rocordod in one week, the incidence docroasod and no further outbreaks have boon recorded since 7 Fobruary. The Austrian authorities adopted rigorous r.10asuros of slaughter and vaccination. An urgent request to tho Cor.1oission for supplies of vaccine for tho purpose of intensifying tho control oeasur0s was dis cussed at a special r.�ooting of tho E:x:ocutivo Cor.1rnittoe in Dublin in ,January 1957 nhen it -:ms docid.:Jd to release 500 frori1 the Special Account of tho CoLmission for tho purchase of tho vaccine, which ·,;as nado available 0,t a specially reduced cost by tho Netherlands Govern □ont. This vaccine m.1s used to comploto, as :i:ar as possible, vaccina tion of anir,mls in tho Upper Austrian and Salzburg area where tho infection vm.s hoaviost and to broaden tho zone of vaccination.

�n,

Tho E:x:ocutivo Coomittoc have noted with ouch interest that Y1here reliable vaccine ·;,as properly or systoraatically a.pplied, outbreaks of tho disease arc either prevented or, whon they occur, arc quickly brought unclor control. Vaccination appears to have made a notable con tribution in limiting tho spread of tho disease throughout Europe. Vfoito to different count,rien by lloubors of the Secretariat The countrios visited by the Secretariat are onur.10rated in the previous section. Special note, however ? should bo ran.de of tho vis.its in 1956 to tho Netherlands, Denoark, Franco and the United States of .Auerica.

12 The visit to the Netherlands was made, together v1ith Dr. I .A. Galloway, Director of tho Virus Research Institute, Pirbright, to study, with Dr. R.S. Frenkel, sorno experiments ·carried out in tho Netherlands on the duration of immunity follovdng tho vaccination of cattle 11ith 11 culturo11 virus vaccine. Systematic vaccination of cattlo in tho Netherlands was begun in February, 1953, a trivalent culture virus vaccine, produced .;d th viruses typos O, A and C being usocl. In tho Netherlands all cattle aro vaccinated and annual rovaccination is carried out g thus, there arc cattlo in the country ·.--rhich have boon vaccinated from one to four timos. During 1954-56 vaccinated cattle have bocn tostod for immunity and thoro is 0, considorablo numbor con cerning v1hich data aro available. Tho rosults of the challenge experi ments showed that tho cattle possessed a satisfactory dcgroo of immunity up to ono year aft or vaccination with, of course, n clocroaso of immunity towards tho ond of that period. Ono of tho visits to Franco was, in addition to attending and participating in tho annual meeting of tho OIE, to visit a private veterinary institute in Tours in order to obtain detailed inforr.iation on tho production of foot-and-mouth disease viruses for vaccine pro duction. Tho method used in this institute consists in the simultaneous production of foot-and-mouth virus and vaccinia virus on tho skin of adult cattle. In July and August 1956 9 Dr. Fogedby worked for eight wooks at tho Danish Veterinary Institute for Virus Research. Ho devoted this time mainly to work on problems of immunity to foot-and-mouth disease and tho typing of viruses. In Soptombor 1956, by special invitation, Dr, Fogedby attondod tho official dedication of the new Animal Disease Laboratory, Plum Island, United States of America and also took part in a symposiur.i on vesicular disoasos of livestock, Tho major emphasis of tho future research at this lc:boratory i,-1ill bo on foot-and-mouth disoaso: other vosi-cula-r typos of diseaso, o. g, vesicular stotJ.atitis and vosicular exanthoma ·.-rill also be studied. Ho also visited other laboratories in tho country for discussions on different virus problems. Viait to Bolgiuo by Joint OIE[Coo11ission Group

At tho mooting of tho Ex:ocutivo Committoo in Soptombor 1956, Prof. Fluckigor roforrod to tho nood for more onorgotic action in tho control of foot-and-mouth disoaso in some European countries with special roforonco to tho slau[shtor of infoctod animals and a vaccination schomo. Ho oxprossed his willingness to participate to tho fullest oxtont in any action -to induce countries liko Belgium and Franco to improve tho position. His suggo3tion was that Dr. Fogodby, rep:::,osonting tho Commission, and ho, representing the OIE, Ghould toeothor visit tho:30 countri os and discuc1s tho subject v.rith th0 veterinary authoriti cs, senior govornmont of.ficials and, whore nocossary 1 v.rith Ministers, The Executive Committee agroud to this suggestion, with tho inclusion of another membor of tho CommiGsion 1 s Standing Technical Committee, Dr. van den Born, in tho visiting group. The Government of Belgium expressed

- 13 -

its willingness to receive the group and suggested that :Dr. G. Ramon, Director, OIE, should join the group. Unfortunat0ly, after full arrangements had been completed for tho visit, neither Prof. Fluckiger nor Dr. Ramon found it possible to make the visit. The representatives of tho Commission were warmly received by the Minister of Agriculture and the veterinary officials. The Minister summarized tho foot-and-mouth disease position in Belgium and expressed his confidence, shared by practicnlly every Belgian farmer, in vac,cina t±on as a means to control tho disoo.se. For the tir;ie being, a slaughter policy could not be introduced in Belgium. It ua.s, however, evident that the number of outbreaks of foot-and-mouth diseas0 was closely collated to tho extent of vaccination and; thorcforo, as much vaccina tion as possible is being encouraged throughout tho country. Proposal to amend the Constitution of tho Commission At tho Second Session of the Commission, the observer from Portugal statcxl that his govornmont intended to become a Member of ·tho Commission, but that his government strongly felt that the annual con tribution for Portugal fixod in tho Constitution was excossive ancl suggested that it should be halved. In 1955, Portugal became a Hor.:ibor of tho Commission. In a lotter of 23 Novombor 1956, tho Portuguese Govornmcmt informed tho Chairman of tho Cor.iuission and the Diroctor-Goneral of the Food and Agriculture Organization that tho Portuguese roprosontativo had boon instructed to propose at tho next session of tho .Commission that th0 Portugu·eso· con tribution b0 roducod to �n50 per annum and asked that this subject be included in tho Agenda. In accordanco with Article XIV of tho Consti tution of tho Commission, tho Diroctor-Gcmoral of tho Organization informed all Members of tho Commj_ssion 11bout this request for an amond ment of tho Constitution and that an appropriate i tom would: bo incJ.uilod �n the Agenda for tho forthcoming session of tho Commission. ',: Tho Commission ondorsed this report. In tho course of tho discuasion, th'? Secretariat reported that it was hoped to finalize at an early dato tho arrangements that the Virus Research Instituto� Pirbright, Unitod Kingdom, would be the C antral Roforonco Laboratory' for foot-and-nouth disoaso and that unclor FAO arrangements it was intended also to use this institute as a World Roforonce Laboratory. In connection with tho duration of j,mmunity oxporiments, tho Con mission decided strongly to support tho carrying 01-1-t of thC largo exporiraont which was agreed w:i.th tho joint OIE/Comrllission group in Paris. It should !i1ak.e this known to OE.EC and invite financial support for this experiment and to a lessor extent for tho smaller cxporimcnt proposed to bo done in Belgium. Furthor 9 in order to explain tho need for and tho value of this major oxporimont, it was docidoa to tak.o advantage of tho offer of FAO to ask Sir Thomas Dalling to attend tho mooting of tho Ministers' Doputios of OEEC.

- 14 Supplementary statements were made in c·onnection with the reJ)ort on the disease position in certain countries. Tho delegate from Deninark and the delegate from the United Kingdom made statei;1ents. The delegate from tho United Kingdora reported that there had boon four primary outbreaks of disease during the wonth of March 1957. The delegate from Denmark -reported that there had been olevon outbreaks in the southern part of Denmark, three of which wore in Jutland, Most of thoso outbreaks were of As and o2 typo virus, consistent with tho typos being found in outbreaks in the neighbouring part of Western Goroany. However, rocontly a C type virus had been encountered and supplies of vuccinc against this typo \7ero not entirely adequate and it might be .. that this virus typo would dominate the situation, ·.-,hich tho dologato considored ,night d.etoriorat o in the next few 'l'!ocks. · The st.:i.nping-out policy v1as being used in supplor.1ont to vaccination, but tho delegate v1as not confident that this could bo uai.nt{l.inod· if tho outbreaks became too numorous, because of financial difficulties. Budget and Accounts Tho Co17lmission adopteel· tho accounts for 1956, tho revised budget for 1957 and tho budgot submitted. for 1958. Those had boon prepared by tho Diroctor-Gonoral of Fl-1.0 and submittod to tho Cor,1r:iission by tho Ji.Jx:ocutivo Committee. It was oxplainod that tho item on tho budget of $3,200 for Consultants wo.s to ensure th::i.t tho services of Sir Thomas Dal ling 1.-muld bo _available in a consultant capacity. Future Activi tics of the Comr:iission Note was taken of. the future activities of the Coornission, as out1inod b olov,r. Following upon the preliminary -:rork which tho Cor,1□ission had to undertake in order to becouo fully acquainted with tho nothods of con trol of fo'ot-and-mouth d.iso;J.so in tho different Europonn countries and to r.i.ako contact with veterinary and other officials in those countries by visits and other moans, the tino hGs now arrived when it is possible to _give attention to 2-n overall control program for Europa. To this end a __ mooting of tho Comr.iission 1 s Standing Technical Com[1ittoo took pla,ce on 1 April 1957 in Romo -whon the subject nas fully discussed and a plan ,ras elaborated anfr placed boioro tho Commission at its Fourth Session on 2-3 .!pril 1957. Tho Coomission will continue to koop in close touch with OIE cmd Member :.:md other European countries on the foot-and-mouth , isoase positiop. in Europe witha view to giving any technical advice andany assisi;a:nco possible to individual countries.

- 15 The Commission v1ill continue to lay oonsidorablo stress on an officiant reporting systoi;1 \-1horoby early: intimation of outbreaks of tho disease is given and tho information speedily transmitted to intorostod countries, Close collo.boi•n,tion with OIJE on this sub joct will b o main tained, Tho Cor.1mission will continue to maintain interest in tho foot-and mouth disease position throughout tho uorld, especially in countrion from ,vhich tho responsible viruses r:iay, by any r:10ans, be introduced into Europonn countries. 'l1his v,ill bo offoctod. through close collaboro.tion with OIE and by any other appropriate methods. Tho Comnission will continue to collaborato ·with other organizations, international or othorvviso, o.g. OIF., OEF.C, otc,, in carrying out n,ny oxporiraonts or in any other uay to study problo□s loading to nothods of control of foot-and-nouth d.ise0,so, The Cor:rr:lission, roc,lizing tho inportanco of research work, will maintain its int orost in such vrork in institutos throughout tho world and adopt such procedures r.s aro necessary to obtain first-hand infor nation on tho results of such work. Visits \-.,rill bo 11ado to different countries by tho Secretariat a.nd raoobors of tho CoLl□ission I s Standing Technical Cammittoo, whore con sidor,ed necessary, with tho approval of tho Ex:ecuti vc Counittoc, Report of tho Standing Technical Comaittoo A ueoting of tho Standing Technical Co□nittoo was hold in Ro□o on 1 April. Thero wore prosont� Messrs. I. Altara, H,S, Fronkol, I.A. Galloway, E. Michelson, J.N. Ritchie, B, Ubertini, J.M. van don Also prosont wore Born ,A1cl Dr .. E, Fogoclby. Dr• G. Bolclrini, Sir Thouns Dalling o.ncl Dr. W. Ross Cockrill. Mr. J.N. Ritchie was oloctod. Chairoo.n for this □coting. Overall Plan for tho Control of F oot-and-1'./louth Disoas o in Europe Thoro -;-ras u full discussion on this subject, Tho Counittoo was satisfied that vc,ccination had boon sho1;m to bo valuable in tho control· of foot-and-1�1outh disco.so and we.s applicable in r,1ost European countrios, It should bo consiclorod as e noans to bring tho disoaso sufficiently under control so that ovontually a stnr:iping-out policy r;1ight bo adopted. It is thoroforo rocor.ir.10ndod that in those countries whore a heavy weight of infection is present or whore thoro is a continued throat of infec tion, tho policy shoulcl bo systooatic vaccino.tion, Tho systo1:1 r.iay vary in accordance -.:rith tho circuostancos in tho particular country. It nay bo possible, for oxo.r.1plo, to adopt annual vaccination of all cattle stock in tho country, or vaccination Day bo done around foci of infection, or in throc1.tonod aroc1s. When tho nunbor of outbreaks has boon suffici·ontly roducod, vnccinntion nay lJO supplo□ontod by -slaughter of anir.mls on infoctod prouisos. 1,' vtor, thoro nay bo 2. reduction in routine vaccination and tho stanping-out policy r.1ay bo adopted as tho □ain uothod

- 16 of control. This st�go nay ntit be ranched in a particular country until its neighbours and countri os from ·,1hich inports 1 l)articularly of livcstock, arc nadc, ha vo r cached ::i, sir:iilnr position. Only after this stage, \7ill it bo possibl·o to roly entirely on a sto.uping-out policy. It is obvious the,t sufficient sup:plios of trustrJOrthy vnccinos i:mst be avnilablo c1nd th2.t there is a staff capable of orgc1,nizing and carry ing out tho vaccin2..tion. It 17lust be cr.rphasized that, whatovor tho policy, it is essential to control tho novonent of stock, to dispose of ·infoctod naterinl and to carry out effoctivo disinfection. Tho Cor:ii:1i ttoo was i1:1prossod '.Iith tho success of tho vaccination policy in those countries whore ·1 t hc1s been systematicG.lly applied. Not only has the number of outbreaks boen -reduced, but the weight of infec tion has been Minimized, because, as a eoneral rule, only young cattle and pigs have succumbed to infection, In order to have a star.1ping-out policy, tho following points must receive careful applicationg 1) Early notification of a suspicion of th0 presence of tho disease must be available. 2) A very meticulous system of dealing with such reports must be in. force and ·must be. r0adily · 1�ut into effect - the system must include rapid. diagnosis - immediate control of movement of s.tock over an area - iurnediate quarantine of the suspected or inrected farm - tracing of all cont'act animals and slaughter of direct contacts on oth6r farms., e.g. anir.mls recently moved. off the infected. place and �nimals handled by th0 ovvn0r of tl10 infect od place or his veterinary surgeon after contn.ct with infection.

Rapid m9ans of slaughter etnd. disposal of carcasos on the infected. place,

4) An organizn.tion cn.pable of dealing with all tho detailed tr::i.cing of stock ,;rhich is necessary. 5) A system of recording movements of stock must be permanently in force and enforced to allow of easy tracing of animals. 6) Visits to examine stock in tho vicinity of outbr0aks must be made to discov0r secondary outbreaks as early as possible and also to discover whether the first reported case is in fact the primary ono, 7) There must be considerable elasticity in financie.l arrang0-ments to-allow of vigorous pu:rsuit of the policy. 8) The farming community must be willing to cooperate in every aspect of the work.

r1...o/57 /4/2671

- 17 In most European countries a stamping-out policy, not supplemented by va,ccination, is irapracticable, but the Committee regards a stamping out policy as tho ul�im�te objective. Supply of Vaccines The question of sup.plies of vaccine was also discussed, particu larly tho part which tho Commission may play in arranging for supplies for countries in which the amounts available for any special purpose The Committee considers that the Commission should were insuffic"ient. satisfy itself that the tests for innocuity and potency carried out i_n the centres from which it obtains vaccine are adequate and that consideration should be given to the desirability of supplementing those by periodic-check tests. It was decided that these points shouJ.d be discussed in detail at an on.rly mooting of tho Committee and to facilitato thoao discussions the Secretariat should obtain inforr;mtion on tho methods of production and tho tests for innocuity and potency currently in use in supplying laboratories 'in Member countries. Rocont Progress in Virus Cultivation Tho Cammittoo discussed tho progress :j.n cultivatio.n of virus for vaccine production. Cultivation on tissue has so many advantages f'or tho production of vaccine that further work should continue to be done on tho subject. Thero is avid.once of improvement ih tho immunizing value of the vaccine following the roaninalization of culture virus, It is roalized. that various strains behave differently in culture and tho advantages of roanimalization probably apply more particularly to certain strains. Novurtholoss, tho immunogonic cho.ractor of strains passaged continuously in culture should be oxarained periodically. In view of tho practical difficulties v7hich ariso in certain countries in obtaining sufficient tongue tissue for largo-scale produc �iorr, consideration of tho possibility for using o�her tissues for vaccine production should c-1ntinuo to be given and particularly it would be inportant to oxporinent with tissues which would bo readily available ,for largo-scalo production. Following discussion in which members of tho Technical Committee took part, tho report was adopted.

It was agrood that there should be added to tho section on supply of vaccine, tho recommendation that ondoavours be r.iado for tho cost of vaccine from producing countrios, supplied for international assistanc0 through tho Commission, to bo as low as possible. Suggestions for a rocomnend.ation that tho costs of vaccination in a country should 1:io borno by the State and that tho production of vaccine should bo carried out only in State institutes wer� not supported.. For tho purposes of "cordons sanitaires' 1, howovor, it vras folt that the cost of vaccination 1;1ight be borne by tho State.

F;,.0/57 /4/2671

- 18 Amondr:10nt to the Consti tut ion of tho Comr;iission 'l'ho Cor.1':lission agreed to reduce the c..nnual contribution of tho Government of Portug�l fror,1 US $1,500 to US �n50, and docidod thc:.t Appendix I to tho Constitution of tho Commission .s.hou_ld b.c nodifieel accordingly. Since Appendix I consti�utos an integral part of the Constitution of the Co!ilr.1ission in n.ccordance with tho provisions of Article XIII .1, this rnouificatioh entails .::i. consti �utionnl m1011dmoYJ.t. Tho Commission furth0rmoro decided to ar,1011d tho third sontonce of Article XIII. l of tho Constitution to read o..s follo",7S i "Tho budget for the c:.dG1inistr2.tivo activities of tho Comuission for tho first fivo years sh:111 l,e ort the oasH of US ��50 ,ooo annually, subject to any modificn tion which during this 1,eriod might bo t:1::i.clc· by constitution.:11 r'.'.·.1cn-1··· ·,, to ApJ)Gnc1.ix I. To this sun shall b o :i.ddod any. contribution nndo by Wo□bers in conforr:iity v,ith paragraph 2 ·bolov.r". c

Tho Cor_1mission roq_uostod tho Director-Gonornl to suboit those -b,10 amonduonts to tho FA0 Council in accorclo..nce ;1ith tho roquiromonts of Article XIV .1 of tho Constitu.tion. of tho Cor:unission. 1

Application from tho Government of Groece to join tho Commission It was explained that corrospondonce had been excho.,ngocl -:.rith tho Greek Gcivornr:ient nho intimcJ.,tod thoir wish to join tho Cor:imission, pro vided tho annual contribut.ion was roducod fron US ��l, 500 to US $750. Both the Ex:ocutive Coui-;iittoo and the Commission considered this request favourably. Ho .-10vor, it was po:i..ntocl ou:t th:::-.t though Gr coco could join tho Coumission forthwith by dopositing e. notifica tio,n of acceptance of tho Constitution, tho suggestion that tho contribution of Greece be roducod coulcl not be acted upon £!.t tho currant session o;f tho Cor,1mission · coivod loss than 120 days before tho session .. If thoroforo since it vms ro the 2.dherence of tho Govornmoht of Greece is of:foctod in 1957, this adherence would be on tho basis of tho Constitution as it 1101;1 stands. In view of this, tho Con1mission_ agrood the. t tho contribution of. tho Govo · rnnont of Grooco for 1957 could be paid in tvm eq_ual instalments, the first at the time of adhoronce 1 ·.::incl. the second in the beginning of l958, Should tho Fifth Session of the Commission. adopt the necessary amendment to tho Constitution, it could d.ocid·o oi thor to waive tho second instalment 9 or to apply it to tho contribution ··of the Gover11r.11:mt of Grecco for 1958. 1

Any other Business Tho· Com111ission �grood that -.:1hero tho Ex:ecutivo Comr;iittoe, in accordance with Article XI,5 and othor Articles of tho Constitution 5 is authorized to take action "in emergency (Art:i,cle V.1), it .would be doemod

1 l ,T.':n I I / '-, , .. ·'·'-' / .:·,-,

·t/2671

- 19 to conforn with this authorization if the Exooutivo Comr:1ittoe took action aftor consultation between the Chairnan, members of tho Exocutivo Cor:u::1ittoo and tho Socrotariat, without tho need. for a r,10oting of tho Exocutivo Comuittoe. Tho Socreta,riat reported. that, following d.iscuss_;i.on at the last r:i.eeting of tho Etcecutivo Cor:i.rai ttoo on tho risks of introducing foot-and r.1outh disease into Europe fro1�1 countries in which tho disease was onclorJic, a r.101:1orand.uo had boon prepared and prosontod to tho Diroctor-Genor.:1:l of FAO and, further, that suggestions had boon □ado on possible action. Tho Cor:mission oxpressod tho hopo that this subjoct would bo discussocl at tho FAO Conforonco in Novonbor 1957. A suggestion was made for the creation of an international fund from which there could be met some of the expenses incurred by a country invaded from outside sources.

FJ.O /57 /4/2 671

- 20 -

A P P E N D I X I

BUDGErS FOR 1957 Atill 1918 (Note by the Director-General of FAO)

1958

Budget

1. In accordance with the Constitution of the Commission and with its Financial Regulation III 9 I present herewith the proposed Annual Administrative Budget for 1958, 2. The budget estimates have been drawn up in the form established in the Ftnancial Regulations. 3, At this stage I have no 11 supplemontary details" with respect to Chapter II but am presenting tho estimates here in a single total in accordance with Financial Regulation 3.2. No expenditures have so far boe� made under this Chapter and in tho absence of any experience to guide mo I recommend that an arbitrary sum of $5,000 be provided hero for 1958; this is the same amount as was allowed in tho approved 1957 budget.

It will be noted that tho proposed Annual Administrative Budget for 1958 totals j�50,ooo, i.e. the maximum potential contributions from Member Governments that may be received by the Commission. I roalize 1 of course, that tho Commission may not actually receive tho full amount of $50,000 (at tho time of preparation of this budget it is possible to count on only $24,750); in that event expenditures under Chapter I�I of the budgot 1 Contingencies, would be restricted in order to keop total oxpondituros within tho limits of tho funds actually received.

5. A request has bo0n received from Portugal that its annual contribu tion bo reduced from jH,500 to �n50. If tl10 Commission agrees to this reduction, the total proposed Annual Administrative Budget would bo reduced accordingly to $49,250, with a further corresponding reduction in Chapter III of tho Budget, Contingoncios.

- 21 6. Vnder Article 1 "Personal Services" of Chapter I the budget estimates allow for one P-4 Assistant Secretary to tho Commission, one G-;4 Stenographer and the services of a Consultant. Thero is no·chcmgo in tho Articles "Travel", 11Mootings 11 or 1 1Miscellaneous 11 as againzt the rovisod 1957 budget. 7. In tho Special Budget for tho Special Account, 1958, I recommend that the sum of $3,000 be provided to cover travel and per diem of members of tho Stancling 'rechnical Committee ( soc para.. 10 bolow).

1957

Eude;ot

8. In accordance with Financial Regulation 4.5 I am also reporting a transfer of $3,600 from Chapter III to Chapter I of tho 1957 budgnt. In Chapter I the 'I'ravel and Meetings Articles remain the same but I consider it nocossary to increase tho provision for Personal Sorvicos to cover tho cost of additional allowances and tho services of a Con sultant. A reduction of $100 has boon made in the Miscellaneous itom. 9. Should tho reduction in contribution roQuestod by Portugal (soc para. 5 above) bo agr eed for 1957, then tho total budget for 1957 would be reduced from �P50,000 to $49,250, ·.vith a corresponding decrease in Chapter III, Contingencies, 10. I suggest that tho Special Budget for tho Special Account in 1957· bo revised and increased from $1,500 to $10,500, $3,000 of this sum. is to cover tho cost of travel and por diem of members of tho Standing Technical Committee. Loss travel than anticipated was undertaken in 1956, but because of tho threatening foot-and-mouth disease opizootic it is oxpocted that tho Technical Committee will bo required to travel considerably in 1957, and adoQuato provision should thorofore be mado to cover this eventuality. $7,500 arc required to cover tho cost of vaccine sent as an emergency measur,e to �ustria, in accordance with tho · ·rocont d.ecision in Dublin of tho Eiocutiyo Committoo. 11, I attach at Table A tho revised Annual Administrative Budget for 1957 7 incorporating tho transfers I ha VG offoctod, together with my proposed budget ostimates for 1958; at Table B a Summary showing by Article tho provisional expenditure in 1956, tho 1957 revised budget and the 1958 proposed budget; and at Table Ca note giving tho Special Budgets for tho Special Account for 1957 and 1958. Assistance given by PAO 12. Bosidos the above oxpondituro there are it·oms which have not boon included which arc provided by tho Organization. Those items not charged to tho Commission include tho part-time services of senior officials of th<:acBfMn�tion, tho services of tho Budget and Finance units, accommodation/ supplies of stationery, otc., as wall as postal and cable charges. F. :;·-.7 /.·. ''-0 671 -.i. -

.,,, "":

, I

ANNUAL ADTuIINTSTRATIVE BUDGEr FOR 1957 (REVISED) Sourceg Members of the Commission Amount: (a) Contributions due in respect of 1957

$ 24,750

(b) Possible additional contributions

25,250

GRAN]) TOTAL Source;

Members of the Commission

Amount: --

Possible Contributions in respect of 1958

50,000

50,000 r· .·

us�

16,700 4,500 • 500 100 --21..000 23,200

GRAND TOTAL

ANNUAL ADMINISTRATIVE EUDGEI1 FOR 1958 Application of Resources Chapter I Administrative Ex:penditure under Articles IV and XII.2 of tho $ 50,000 Constitution 1. Personal Services Salaries, Established posts $10,800 Allowances 3,800 Consultants 3,200 2. Travel 3. Meetings of tho Commission 4. Miscellaneous Sub-total Chupter I: Chapter II Ex:pendituro under Article V of the Constitution Sub-total ChaptGr II; Chapter III Contingencies Sub-total ChC1.ptor I-IIi

GRAND TOTAL :1 · .--. /s7

Application of Resources . Chapter I Administrative Ex:penditu.re under ----- Articles IV and XII.2 of the Constitution 1. Personal Servic:�s . Salaries j Established posts $10,500 3� o·oo Allowances 3,200 Consultants 2. Travel 3. Meetings of the Commission 4. Miscellaneous -- --Sub-total Chapter r� Chapter II Expenditure under Article V of the Constitution Sub-total Chapter II� Chapter III Contingencies , Sub-total Chapter IIIg

TABLE A

G RAlID TOTAL

21,800 5;000 23,.200 50,000

=---=

17,800 4,500 500 100 '21 000 22,100

22,900 -2.t.q_QQ

22,100 50 '.,000

1\3 f\)

- 23 TABLE B

SUMMARY OF BUDGETS FOR 19'56, 1957 and 1958 .. 1956 (Provisional) Expenditure GRAND TOTAL fil{APTER I 1.

.�

Personal Services 1.1 1.2

1.3

Salaries, Established Posts Allowances Consultants

Travel

Meet ini·-·-�f

Miscellaneous

... . .. ----·· -- .... -••-- ,

the Commission

Sub-Total Chapter I CHAPTFJR II CHAPTER III

�r 18,141

1957 Revised · ... Budget $(50,000

1958 Budget $

50,000

12,276.20

16,700

17,800

( 10 , 08 5.• 50 ) ( 2,190.70)

(10,500) ( 3,000),

·( . :y;200 )'"

(10, 800) { 3,800) ( 3,200)

4,162.83

4,500

299.20

500

71.7o

100

(16,809.93)

(21,800)

(22,9 00)

5,000

23,200

22,100

- 24 TABLE C SPECIAL BUDGEI'S FOR THE SPHJIAL ACCOUNT

];ill Spo0ial Budget 1 Travel and per clioi:1 of r.ior.1bors of .th·o Sto.nding_ Technical Cor:1Dittcc

- 7' 5 0 0

Vaccine supplied-to Au�lria

Total

3,000

$ 10,500 - ....... -

l2.2i Special Budget 2 Travel o.nd per dior.1 of r.1or.1bors of Cor.1mittoo tho Sto.nding Tochnical _

3,000

- 25 AP:PENDIX II

ACC6mrrs ioR THE YEAR ENIJ�D 31 DECE\IIBER 1956 Gonoral Aocount. . �drn,:iJ_1_istratiom Personal Servicos 12,276.20 Travol 3,936,67 Mootings of tho Commission 299,20 71.92 Miscellaneous Balance at 31 December 1956 transferred to Spocial Account

-:-':.. -=-..··,·.--·.tJI:ombor

Government contributions rocoivod in rospect of 1956 (Schodulo I) 24,750,00

16,583.99 82 166.01 i24, 750 .. 00

$24,750.00

Spacial Account Technical Committoo - travel Balance at 31 D.ocornber 1956

599.47 Transferred in accordance with tho Resolution of tho Second Session of tho Commissiong Dalanco at 1 Jan, 1956 7,800.67 Contribution in arrears rocoivod during 1956 (Schedule II) 4,000.00 Lapse of· 1955 Aooruod Liabilities Transferred from Gonoral Account $20,067.86

101.18 8,166.01 $20 � 667'.86

- 26 -

Balance Shoot at )1 Doc0mbor 1956

L i a b i 1 i t i o s Sundry Creditors Special Account Contribution rocoivod from Italy in advance

A s s o t s

241.00 ·19,468,39

3,694.50

$ 23,403.89

Current Account vri th tho Organization

23,403,89

$ 23,403,89

- 27 SCHEDULE I 1956 Contributions Mombor Nations Austria Denmark Iceland Ireland Italy Noth orlands Norway Portugal Turkey Uni tad Kingdom Yugoslavia

Amount duo

Amount rocoi ved

1,500.00 2,500.00 250.00 750.00 5,000.00 2,500.00 750.00 1, 500-.00 1,500.00 7,000.00 1,500.00

1,500.00 2,500.00 250,00 750.00 5,000,00 2,500.00 750·. 00 1,500. 00 1,500.00 7,000.00 1,500.00

�1 24,750 .oo

$ 24,750.00

Amount outstanding a·� 31 Decembor 195t5 $

SCHEDULE II Statement of Contributions in Arrears Year 1955 $ Austria Italy Portugal TurkGy

375.00 2,500.00 375.00 750.00

Amount Amount recoivGd outstanding at in 1956 31 December 1956 $ $ 375-.00 2,500.00 375.00 750.00 �� 4,000 .oo