The hospital for sick children handbook of pediatrics, 12e (may 12, 2022)_(0323713408)_(elsevier) 12

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The Hospital for Sick Children

HandbookofPediatrics

Stajf Editors

Dr. Deborah Schonfeld

Dr. Shawna Silver Fellow Editors

Dr. Catherine Diskin

Dr. Siobhån Neville ELSEVIER

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The Hospital for Sick Children Handbook of Pediatrics

The Hospital for Sick Children Handbook of Pediatrics

EDITORS

Deborah Schonfeld, MDCM, FRCPC

Sta Physician, Division of Emerency Medicine

Department of Pediatrics, e Hospital for Sick Children

ssistant Professor, Faclty of Medicine, niversity of oronto

Shawna Silver, MD, FRCPC, PEng

Sta Physician, Division of Pediatric Medicine

Department of Pediatrics, e Hospital for Sick Children

ectrer, Faclty of Medicine, niversity of oronto

Catherine Diskin, MB BCh BAO, MSc, MRCPI

Pediatric Medicine Fellow

Department of Pediatrics, e Hospital for Sick Children

Siobhán Neville, MB BCh BAO, MSc, MRCPI, MRCPCH

Pediatric Medicine Fellow

Department of Pediatrics, e Hospital for Sick Children

Elsevier

1600 John F. Kennedy Blvd. Ste 1800 Philadelphia, PA 19103899

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ABK F PEAS, EF E

Copyright © 2022 by Elsevier, Inc. All rights reserved.

o part o this pliation ay e reproded or transitted in any or or y any eans, eletroni or ehanial, inldin photoopyin, reordin, or any inor ation storae and retrieval syste, ithot perission in ritin ro the p lisher etails on ho to see perission, rther inoration aot the Plisher’s perissions poliies and or arraneents ith oraniations sh as the opy riht learane enter and the opyriht iensin Aeny, an e ond at or esite .elsevier.operissions

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Notice

Pratitioners and researhers st alays rely on their on eperiene and nolede in evalatin and sin any inoration, ethods, oponds or eperients desried herein Bease o rapid advanes in the edial si enes, in partilar, independent veriation o dianoses and dr dosaes shold e ade o the llest etent o the la, no responsiility is assed y Elsevier, athors, editors or ontritors or any inry andor daae to persons or property as a atter o prodts liaility, neliene or otherise, or ro any se or operation o any ethods, prodts, instrtions, or ideas ontained in the aterial herein

Previos edition plished nder title he S andoo o Pediatris

Library of Congress Control Nuber

ontent Strateist aryeth hiel ontent evelopent Speialist eredith adeira

Plishin Servies anaer eepthi nni

Proet anaer adan orde Selvanadin esin iretion Patri . Ferson

Printed in the nited States o Aeria ast diit is the print ner 9 8  6

Working together to grow libraries in tleveloping countries

is book is a general guide only and should never be a substitute for the skill, knowledge, and experience of a qualied medical professional dealing with the facts, circumstances, and symptoms of a particular case Neither the ublisher nor the uthors assume any responsibility for any loss or inury andor damage to persons or property arising out of or related to any use of the material contained in this book. t is the responsibility of the treating practitioner, relying on independent expertise and knowledge of the patient, to determine the best treatment and method of application for the patient.

– e ospital for ick hildren

DEDICATION

To…

All the students, residents and fellows whom I have taught and have taught me, and to mom and dad—the most inspiring pediatricians I know. DS

To…

All the children, families and colleagues from whom I have learned so much, and my family—you are truly gems. SS

To…

ose that support me, family and friends. CD

To…

My closest champions and condantes, whose patience for me talking about this proect knew no bounds. SN

Foreword ix

Preface xi

Acknowledgments xii

Chapter Authors xiii

Common Abbreviations xviii

Section I: Acute Care Pediatrics 1

Chapter 1: Resuscitation 2

Chapter 2: Emergency Medicine 30

Chapter 3: Poisonings and Toicoogy 1

Chapter : Pain and Sedation 3

Chapter : Procedures 10

Section II: Suspeciaty

Chapter : Adoescent Medicine

Chapter : Aergy 13

Chapter : Cardioogy 1

Chapter : Chid Matreatment 21

Chapter 10: entistry 22

Chapter 11: ermatoogy 23

Chapter 12: eeopment 2

Chapter 13: iagnostic Imaging 22

Chapter 1: Endocrinoogy 2

Chapter 1: uids Eectroytes and Acid–ase 32

Chapter 1: astroenteroogy and epatoogy 31

Chapter 1: enera Surgery 0

Chapter 1: enetics and Teratoogy 2

Chapter 1: roth and utrition

Chapter 20: ynecoogy 

Chapter 21: ematoogy 1

Chapter 22: Immunoogy 0

Chapter 23: Immunoprophyais 

Chapter 2: Inectious iseases 00

Chapter 2: Menta eath 2

Chapter 2: Metaoic isease

Chapter 2: eonatoogy 1

Chapter 2: ephroogy and roogy 0

Chapter 2: euroogy and eurosurgery 02

Chapter 30: ncoogy 30

Chapter 31: phthamoogy 

Chapter 32: rthopedics 

Chapter 33: toaryngoogy 02

Chapter 3: Pastic Surgery 2

Chapter 3: Respiroogy 0

Chapter 3: Rheumatoogy 2

Chapter 3: Technoogy and Medica Compeity 1

Chapter 3: Transpantation 1001

Section III: aoratory Reerence aues and Transusion Medicine 1013

Chapter 3: aoratory Reerence aues and Transusion Medicine 101

Section I: rug osing uideines 1111

Chapter 0: rug osing uideines 1112

Inde 12

FOREWORD TO THE 12TH EDITION

It is a privilege and a pleasure to write the foreword to the 12th edition of e Hospital for Sick Children Handbook of Pediatrics. Wh do I regard this as a privilege and a pleasure

It is a privilege to be associated with an iconic pediatric “bible” that has provided such value to so an generations of child health students and clinicians. e consistent ecellence in presenting coprehensive state of the art evidencebased practical guid ance has ensured that this handbook has not onl endured into its 12th edition over ore than  ears since the 1st edition but iproved and reinvented itself with ever new version. e Hospital for Sick Children or Sickids as it is aectionatel known has been a world leader in the provision of clinical care and research in child health for over 1 ears. enerations of learners have travelled fro across the world to train here and Sickids is faous for its leadership in teaching. ere are currentl 2 inpatient beds  visits to our ergenc epartent and 2 visits to our abulator clinics annuall cross the hospital we have close to 1 clinical and research trainees. Sickids is the ost researchintensive hospital in Canada and our esearch Institute is a world leader in discover and cuttingedge science. f note is that this handbook has essentiall been written b our residents and fellows who are oen the unsung heroes of the teaching hospital long hours hard work and together with the nursing and support sta provide the energ that keeps the hospital ticking and the patients cared for 2. anks also to the facult chapter authors and espe ciall to the ditors rs. Shawna Silver and ebbie Schonfeld who have done an out standing ob supervising the trainees and diligentl driving this process fro concept to nish with great deterination talent and skill. Soe of the brand new features include helpful practical chapters on ental Health as well as echnolog and edical Copleit.

It is a pleasure to write this foreword because it is so uch ore fun than  relation ship with the previous three editions. When I was a oung innocent rst ear resident in 1 I carried the th edition of this handbook around in the pocket of  neatl starched white coat. It was thick heav and had a serious red cover. I think I kept it under  pillow when I rarel had the opportunit to reach  oncall roo for a brief nap. oward the end of  residenc it was replaced b the 1th edition which was thinner had a ore soothing blue cover and was still seldo ore than an ar ’ s length awa fro e as I navigated the transition to  new role as unior facult. e 11th edition which was published in 2 was coedited b self and r nne ipchand It has a ellow cover with a bright picture of our hospital atriu and was the rst

edition that had an electronic version which was ust becoing popular at the tie. I reeber ver clearl ust how uch tie and eort it took over the course of two ears to coordinate and edit the ecellent contributions of the one hundred trainee and facult chapter authors. So honestl being invited to write this one page foreword and being able to pass the baton to rs. Silver and Schonfeld and their tea is trul a pleasure

I invite ou to eno and benet fro the cobined eperience and wisdo that coes fro 1 ears in the child health business. I believe that regardless of our level of epertise and contet ou will nd advice and practical approaches that will be infor ative and useful. I salute not onl all those who have contributed to this ecellent 12th edition but also all of ou readers who have dedicated our service to iproving the health of children all over the world

Jeremy Friedman, MBChB, FRCP, FAAP

Interi PediatricianinChief Hospital for Sick Children

Professor and Interi Chair epartent of Pediatrics niversit of oronto

ank you for choosing this 12th edition of e Hospital for Sick Children Handbook of Pediatrics. Much like the pediatric healthcare practiced at e Hospital for Sick Children, this book is up-to-date, evidence-based, interdisciplinary and patientfocused in its approach.

ur intention as e undertook the unieldy task of updating this handbook as to create a practical and applied resource for bedside teaching, study and practice. e hope this tet ill act as a valuable reference for edical students, residents, pediatricians, faily doctors, eergency physicians, nurses and other practitioners ho provide care to children—at e Hospital for Sick Children, throughout Canada and orldide

Content has been etensively revised throughout the handbook, reecting current best practice. is edition has been reforatted, aking it easier to read and navigate. here possible, e have provided algorithic approaches to clinical probles, ensuring the content is accessible and easy-to-use. e have added a ne feature of “earls” and “itfalls” to each chapter, to highlight iportant clinical points and coon istakes or isconceptions. e chapters cover Mental Health, and echnology and Medical Copleity, reecting eerging areas of iportance in clinical practice.

e are etreely grateful to the chapter authors ho have shared their epertise and isdo. e hope that the 12th edition of e Hospital for Sick Children Handbook of Pediatrics ill prove itself a orthy guide and copanion to your study or practice of the care of infants, children and adolescents.

Deborah Schonfeld

Shawna Silver

Catherine Diskin

Siobhán Neville

ACKNOWLEDGMENTS

So many people have helped make the 12th edition of e Hospital for Sick Children Handbook of Pediatrics a reality. In particular, we would like to acknowledge Dr Adelle Atkinson, the Director of Postgraduate edical ducation at e ospital for Sick hildren and Dr. eremy riedman and Dr. Anne Dipchand, editors of the 11th edition of e Hospital for Sick Children Handbook of Pediatrics for their guid ance, wise insight, and support. e are grateful to all of the authors and editors of the previous editions of e Hospital for Sick Children Handbook of Pediatrics for the opportunity to uild on all of their outstanding work. ank you to rika Schippel, e ospital for Sick hildren Pulishing oordinator, for her ongoing help with the contracts and ensuring smooth communication with the pulishers. ank you to Dr. rie ama for her help in the early stages of content organiation and development. any thanks go to aryeth iel, lsevier, for facilitating the process of a new edi tion. Special thanks go to our content development specialists and proect managers at dierent stages, eredith adeira and adan Selvanadin, for eing a tremendous source of advice and support throughout the production process. inally, we would like to thank all of the chapter authors—oth learners and sta—for their dedication and perseverance culminating in the 12th edition of e Hospital for Sick Children Handbook of Pediatrics.

Deborah Schonfeld

Shawna Silver

Catherine Diskin

Siobhán Neville

CHAPTER AUTHORS

Section I:

ACUTE CARE PEDIATRICS

1: Resuscitation

Melanie Bechard, BSc, MD

Fellow, Emergency Medicine (CHEO)

Andrew Helmers, MDCM, MHSc(c), MSc, FRCPC

Fellow, Critical Care Medicine

Lianne J. McLean, MB, BCh, BAO, MHI, FRCPC

Staff Physician, Emergency Medicine

2: Emergency Medicine

MariePier Liree, MBChB

Resident, Pediatrics

Maa HarelSerlin, MD

Fellow, Emergency Medicine

Iwna Baran, MD, FRCPC

Staff Physician, Emergency Medicine

Sanne Ben, MD, FRCPC, D(ABP)

Staff Physician, Emergency Medicine

3: Poisonings and Toxicoogy

amin Ladha, MD, MSc

Resident, Pediatrics

lana a, MD

Fellow, Emergency Medicine

Saihiri Ranaalan, MBBS, PhD, FRCP(), FRCP(C), FAAP

Staff Physician, Emergency Medicine and Clinical Pharmacology & oicology

: Pain and Sedation

ahira Daa, MD

Fellow, Emergency Medicine (niersity of lerta)

Lisa Isaac, MD, FRCPC

Staff nesthesiologist, nesthesia and Pain Medicine

: Procedures

achar Pancer, BPH, MBBS Fellow, Emergency Medicine

Mehan ille, MD, FRCPC Fellow, Emergency Medicine

Jnahan Pirie, MD, Md, FRCPC

Staff Physician, Emergency Medicine

Section II: SUBSPECIALTY PEDIATRICS

: Adoescent Medicine

alene Sinh, MD

Resident, Pediatrics

Samanha Marin, MD, FRCPC Fellow, dolescent Medicine

Alene lan, MD, MSc, FRCPC

Staff Physician, dolescent Medicine

: Aergy

Sehanie rdle, MD Fellow, mmnology and llergy (C Children’s Hosital)

Melanie Cnwa, MD, FRCPC Fellow, mmnology and llergy

Adelle R Ainsn, MD, FRCPC

Staff Physician, mmnology and llergy

: Cardioogy

Michael D. Fridman, MD, FRCPC Fellow, Cardiology

Jnahan n, BMBS, FRCPC, FAAP Fellow, Cardiology

elle Panea, MD, FRCPC, FAAP Fellow, Cardiology

Jennier L. Rssell, MD, FRCPC

Staff Physician, Cardiology

: Cid Matreatment

ani Aarwal, MD

Resident, Pediatrics

Reecca an, MD

Resident, Pediatrics

ldie Aril, MD

Fellow, Pediatric Medicine

Rm Ch, MD, FRCPC

Staff Physician, Pediatric Medicine

Jennier Smih, BMBS, MSc, FRCPC

Staff Physician, Pediatric Medicine

1: entistry

Rdd Mran, BDSc, DCD, FRACDS

Fellow, entistry

Jane H, DCD

Fellow, entistry

Shnna Masse, HBSc, DDS, FRCDC

Staff entist, entistry

11: ermatoogy

Lara Mrrisse, MD

Resident, Pediatrics

imerl anc, MD

Fellow, ermatology

Reecca Le, MD, FRCPC

Staff Physician, ermatology

12: eeoment

Adre illran, MD

Resident, Pediatrics

Claire . en, BSc, MSc, LLB, MPH, MD

Fellow, eelomental Pediatrics

Jenna Di, MD, FRCPC

Staff Physician, eelomental Pediatrics

Amer Main, MD, BHSc, FRCPC

Staff Physician, eelomental Pediatrics

13: iagnostic maging

Alisha Jamal, MD, MSc, FRCPC

Fellow, Emergency Medicine

Jere raici, MD

Staff Radiologist, iagnostic maging

1: Endocrinoogy

J Swemim, BSc, MD

Resident, Pediatrics

Jlia Srara, MD, FRCPC

Fellow, Endocrinology

Jnahan D. asserman, MD, PhD

Staff Physician, Endocrinology

1: uids Eectroytes and Acid–ase

Lara Becherman, MD

Resident, Pediatrics

mma lrich, MD

Fellow, ehrology

aie Sllian, MBChB

Fellow, ehrology

Damien ne, MB BCh BAO, MSc

Staff Physician, ehrology

1: astroenteroogy and Heatoogy

Ameilia ellar, MD, MSc

Resident, Pediatrics

ileen Crwle, MB BCh BAO, MRCPI, MSc

Fellow, astroenterology, Heatology and trition

mas alers, MBBS, MSc, FRACP

Staff Physician, astroenterology, Heatology and trition

1: enera Surgery

Jnahn Hael, MD

Resident, Pediatrics

Jsna M.linsa,MD,FRCSC,MPH(c)

Staff Srgeon, eneral and horacic Srgery

eres Aie, MD, FRCSC

Staff Srgeon, eneral and horacic Srgery

1: enetics and Teratoogy

Aree Mah, MD

Resident, erology

rer Csain, MD, PhD

Resident, Medical enetics and enomics

Rer MendaLndn, MD, MS, FRCPC, FCCM

iision

Head, Clinical and Metaolic enetics

1: rot and utrition

Jsin Lam, MD

Resident, Pediatrics

Lara inlin, MD, MPH, FRCPC

Fellow, Pediatric Medicine

Mea an den Heel, MD, PhD

Staff Physician, Pediatric Medicine

Mara AleanianFarr, MSc, RD

Clinical ietician, nfant and oddler rowth and Feeding

Alisa BarDaan, RD

Clinical ietitian, Endocrinology

Jrdan Bealie, RD

Clinical ietitian, Pediatric Medicine and Comle Care

else allaher, RD

Clinical ietitian, Endocrinology and Rhematology

Daina alnins, MSc, RD

irector, Clinical ietetics

Alissa Seiner, RD

Clinical ietitian, Endocrinology

Lri ira, RD

Clinical ietician, Critical Care

Lara res, MSc, RD

Clinical ietitian, Pediatric Medicine and Comle Care

ellie elch, BASc, RD

Clinical ietitian, Pediatric Medicine and Resiratory Medicine

Carline Crrie, R, IBCLC

actation Secialist, reastfeeding Program

Lara Mclean, BSc, IBCLC

Registered rse and actation Consltant

Samanha Sllian, R, IBCLC

Registered rse and actation Consltant

Ashle raham, MScO, MHM

Occational heraist, Rehailitation

Serices

2: ynecoogy

Laren Friedman, BHSc, MD

Resident, Pediatrics

Heaher Millar, MIPH, MD, FRCSC

Staff Physician, ynecology

Anali Aarwal, MD, MHSc, FRCSC

Staff Physician, ynecology

21: Hematoogy

Adam an, MD

Resident, Pediatrics

ana Caric, MD

Resident, Pediatrics

Smira le, MD, MSc, FRCPC

Fellow, HematologyOncology

Michaela Cada, MD, FRCPC, FAAP, MPH

Staff Physician, HematologyOncology

22: mmunoogy

Ori Sc, MD, FRCPC Fellow, mmnology and llergy

Amiirah Anarain, MSc, MD, FRCPC Fellow, mmnology and llergy

 im, MD, MScCH, FRCPC

Staff Physician, mmnology and llergy

23: mmunoroyaxis

Ana C. Blanchard, MDCM, MSc, FRCPC Fellow, nfectios iseases

Shama Sd, MD Fellow, mmnology and llergy

Shan . Mrris, MD, MPH, FRCPC, FAAP, DMH

Staff Physician, nfectios iseases

2: nectious iseases

Ran ir, MD Resident, Pediatrics

Jennier am, MD, MHP, FRCPC Fellow, nfectios iseases

Ari Binn, MD, MSc, FRCPC

Staff Physician, nfectios iseases

2: Menta Heat

arielle Salmers, MBBS Fellow, Commnity Pediatrics

Dahne J rca, MD, MSc, FRCPC (eds), FRCPC (sch)

Staff Physician, Child and dolescent Psychiatry

2: Metaoic isease

Carsen reer, MD

Resident, Pediatrics

Resham a, MD

Resident, Clinical and Metaolic enetics

eal Sndheimer, MD, PhD

Staff Physician, Clinical and Metaolic enetics

2: eonatoogy

Am irs, MD

Resident, Pediatrics

Jlia DiLai, MD, MSc

Fellow, eonatalPerinatal Medicine

aas larni

M Ch O, FRCPC

Fellow, eonatalPerinatal Medicine

Aideen Mre, MD, MHSc, FRCPC

Staff Physician, eonatology

2: eroogy and Uroogy

Madalena Riedl, MD, PhD

Resident, Pediatrics

Mallr L. Dwnie, MD, FRCPC

Fellow, ehrology

Anne Shie Blais, MD, FRCSC

Fellow, rology

Jana Ds Sans, MD, MHSc, FRCPC

Staff Medical rologist, rology

Seeha Radharishnan, MDCM, FRCPC, MScCH

Staff Physician, ehrology

2: euroogy and eurosurgery

Drda Drdeic, MD

Resident, erology

rin Char, MD

Resident, erology

Crisina . , MD

Staff Physician, erology

Ahaa larni, MD, PhD, FRCSC

Staff Srgeon, erosrgery

Lia Plcine,MD,MSc,FRCPC

Staff Physician, erology

3: Oncoogy

Am L, BHSc, MD

Resident, Pediatrics

Mhammed Al aimi, BSc, MD, FRCPC

Fellow, HematologyOncology

Reena Paari, MSc, MD, FRCPC Fellow, HematologyOncology

Smi a, MD, PhD, FRCPC

Staff Physician, HematologyOncology

31: Otamoogy

Shel msn, BSc, MD

Resident, Pediatrics

Asim Ali, MD, FRCSC

OhthalmologistinChief, Ohthalmology and ision Sciences

32: Ortoedics

Allsn Shre, MD

Resident, Pediatrics

nni araanan, MBBS, MSc, FRCSC

Staff Srgeon, Orthoedic Srgery

33: Otoaryngoogy

alia reensn, MD, HBA

Resident, Pediatrics

Sharn L. Cshin, MD, MSc, FRCSC

Staff Srgeon, Otolaryngology

3: Pastic Surgery

Lara aman, MD

Resident, Pediatrics

risen M. Daide, MD, MSc, FRCSC

Staff Srgeon, Plastic Srgery

3: Resiroogy

ler res, MBBS

Resident, Pediatrics

allace B.ee, MD, BASc, MHSc, FRCPC

Fellow, Resiratory Medicine

e J. Mraes, MD, PhD, FRCPC

Staff Physician, Resiratory Medicine

3: Reumatoogy

Desmnd She, MD

Resident, Pediatrics

Dilan Dissanaae, MD, PhD, FRCPC Fellow, Rhematology

Shirle M.L. se, MD, FRCPC

Staff Physician, Rhematology

3: Tecnoogy and Medica

Comexity

Sarna Sharma, MD

Resident, Pediatrics

Maria Maran, MD, FRCPC, MSc

Fellow, Comle Care Medicine

Reshma Amin, MD, FRCPC, MSc

Staff Physician, Resiratory Medicine

Sana Mahan, MD, FRCPC, MSc

Staff Physician, Pediatric Medicine

3: Transantation

Lc Dan, MD

Fellow, mmnology and llergy

Jessica P. lsn, MD, FRCPC Fellow, astroenterology, Heatology and trition

risa an Resel, M, PPediarics

rse Practitioner, ier and owel ranslant

ic , MD, FRCPC

Staff Physician, astroenterology, Heatology and trition

Medical irector, ier ranslant Program

Section III: LABORATORY REFERENCE VALUES AND TRANSFUSION

MEDICINE

3: aoratory Reerence aues and Transusion Medicine

hsrw Adeli, PhD, FCACB, DABCC, FAACC

Head, Clinical iochemistry, Pediatric aoratory Medicine

Ssan Richardsn, MDCM, FRCPC

Chief, Pediatric aoratory Medicine

n Li, BSc

Resorce echnologist, Hematology, Pediatric aoratory Medicine

end La, MBBS, FRCPC

irector, ransfsion Medicine, Pediatric aoratory Medicine

Benamin Jn, PhD, FCACB

Clinical iochemist, Pediatric aoratory Medicine

icria Hiins, BSc

Ph Candidate, Pediatric aoratory Medicine

Mar ahrn Bhn, BSc

Ph Candidate, Pediatric aoratory Medicine

Section IV: DRUG DOSING GUIDELINES

: rug osing uideines

laine La, BScPhm, PharmD, MSc, RPh

rg nformation Coordinator, Pharmacy

e All chaers were wrien  residens, ellws and sa  e Hsial r Sic

Children Chaer ahrs are aliaed wih

e Hsial r Sic Children nless

herwise ned.

COMMON ABBREVIATIONS

h increased

g decreased . greater than

 greater than or equal to , less than

# less than or equal to

AAP American Academy of Pediatrics

ABC airway, breathing, circulation

ABG arterial blood gas

AD autosomal dominant

ALP alaline hoshatase

AL alanine aminotransferase

AA antinuclear antibody

AP anteroosterior

A autosomal recessive

A asartate aminotransferase

A abdominal xray

bCG beta human chorionic gonadotroin

BD twice daily

B body mass index

BP blood ressure

BA body surface area

B blood urea nitrogen

C culture and sensitivity

Ca calcium

CBC comlete blood count

C creatine inase

Cl chloride

cm centimeter

C central nervous system

CP Canadian Paediatric ociety

Cr creatinine

CP Creactive rotein

C cerebrosinal uid

C comuted tomograhy

CL central venous line

C cardiovascular system

C chest xray

DBP diastolic blood ressure

DDx differential diagnosis

B steinBarr virus

CG electrocardiogram

LA eutectic mixture of local anesthetic

 erythrocyte sedimentation rate

 endotracheal tube

fu followu

GA grou A Streptococcus

GG gammaglutamyltransferase

G gastrointestinal

G genitourinary

b hemoglobin

C bicarbonate

 human immunodeciency virus

 heart rate

x history

D incision and drainage

BD inammatory bowel disease

CP intracranial ressure

C intensive care unit

 intramuscular

 international normalied ratio

 intelligence quotient

 intravenous

g ilogram

 otassium

LD lactate dehydrogenase

Ls liver function tests

LP lumbar uncture

m meter

µ micro

 male to female ratio

max maximum

mcg microgram

mg milligram

g magnesium

min minimum

mL millilitre

mos months

 magnetic resonance imaging

 musculoseletal

a sodium

aCl sodium chloride

A nonaccidental inury

C neonatal intensive care unit

P nil er os

 normal saline

AD nonsteroidal antiinammatory drug

 oxygen

 oerating room

PAL Pediatric Advanced Life uort

PA osteroanterior

PCC eriherally inserted central catheter

PC ediatric intensive care unit

P eriheral intravenous catheter

P er os by mouth

P hoshate

BCs aced red blood cells

P rn ro re nata as needed

P arathyroid hormone

P artial thrombolastin time

q every eg, qh—every  hours

 every night

c corrected  interval

BC red blood cell

 resiratory rate

BP systolic blood ressure

C subcutaneous

L sublingual

 sexually transmitted infection

tC total carbon dioxide

 total uid intae

D three times daily

C congenital infections including toxolasmosis, other agents, rubella, cytomegalovirus, heres

P total arenteral nutrition

 thyroid stimulating hormone

 uer resiratory tract infection  ultrasound  urinary tract infection

BG venous blood gas

BC white blood cell

 xray

yrs years

Section I

Acute Care Pediatrics

CHAPTER 1 Resuscitation

CHAPTER 2 Emergency Medicine

CHAPTER 3 Poisonings and Toxicology

CHAPTER 4 Pain and Sedation

CHAPTER 5 Procedures

CHAPTER 1

Resuscitation

Common abbreviations

Useful calculations

Team dynamics

Clinical assessment of the ill child

Respiratory support during resuscitation

Circulatory support during resuscitation

Advanced airway management

PALS algorithms

Post-resuscitation care

COMMON ABBREVIATIONS

Also see page xviii for a list of other abbreviations used throughout this book

ABC airway, breathing, circulation

ABG arterial blood gas

APLS advanced pediatric life support

B bagvalve ask

CPAP continuous positive airway pressure

CP cardiopulonary resuscitation

 endotracheal tube

i fraction of inspired oxygen

C functional residual capacity

LA laryngeal ask airway

PALS Pediatric Advanced Life Support

PA pulseless electrical activity

PC pediatric intensive care unit

SC return of spontaneous circulation

S rapid seuence intubation

S systeic vascular resistance

USEFUL CALCULATIONS

 Hypotension (systolic blood pressure)

a , onth , g

b – onths os , g

c – years yrs , 1 3age g

d . yrs , g

 Estimated weight in kg APLS th ed

a – os 3age in os 1 

b – yrs 3age in yrs 1 

c – yrs 3age in yrs 1 

 Endotracheal tube (ETT) size

a ncued  age in yrs 1 

b Cued  age in yrs 1 

 ETT depth

a , yr

i ropharyngeal intubation c at lip age in yrs 1 

ii asopharyngeal intubation c at nare age in yrs 1 

b . yr

i ropharyngeal intubation c at lip age in yrs 1  

3 diaeter

ii asopharyngeal intubation c at lip age in yrs 1 

TEAM DYNAMICS

esuscitation teamwork, communication, and leadership all have a signicant ipact on patient outcoes



eore a resuscitation

 nticipate needs

a Contact necessary personnel eg, respiratory therapy if available, consider anesthesiology and consider available euipent

b Seek help when needed e g , contact anesthesiology or otolaryngology if a dicult airway is anticipated





ssign roles clearly dene roles and responsibilities of each tea eber

now your resources

a ailiarie yourself with the resuscitation euipent of your hospital ward and eergency departent

b now your provincial or state resources for coordinating transfer to tertiary care centers, if applicable

 uring a resuscitation

 A leader should

a er constructie eedback “Please perfor copressions faster—we’re aiing for  to  per inute”

b ink out loud share thoughts and suggestions to create a shared ental odel “ suspect this child has septic shock” Avoid preature xation on a diagnosis and be ready to shi§ perspective

c Perfor periodic reiews suarie and reevaluate the case ¨is helps to ensure adherence to algoriths and oers opportunities for new ideas to reduce bias

d Encourage inormation sharing and bidirectional transission of ideas “Are there other thoughts about which edications should be used before intubation”

e eain “hands o ” if possible leaders who focus on coordinating the tea rather than participating in the resuscitative eorts perfor better §en this necessitates delegating obs that can detract fro focused leadership ie, assigning a specic person to calculate resuscitation edication doses

PEARL

Closed-loop communication is important in a resuscitation; e g , wen ordering epineprine during a cardiac arrest

Proider 1 “Te patient’s weigt is 2 g please gie  2 mg o 11, epineprine intraenously, wic is 2 m”

Proider 2 “.2 mg o 11, epineprine, wic is 2 m, now ready to gie ”

Proider 1 “Tan you, please administer tat dose”

Proider 2 “ose administered”

 All tea ebers should

a se closedloop communication iproves the safety and eciency of care provided by reoving abiguity fro instructions and allowing for correctionsclarifying uestions if needed

b Be respectul vidence suggests rudeness negatively ipacts resuscitation teas’ perforance

c Support amily presence during resuscitation there is a strong parental preference to be present

 er a resuscitation

 very eort should be ade to conduct a debrie ebrieng involves guided re¯ection of edical issues, eotional ipact on care providers, and provides perforance feedback to the tea

 ¨ere are any debrieng forats eg, standardied fors, “hot” debrief within inutes to hours of the resuscitation, “cold” debrief days to weeks a§er resuscitation

 nsure your hospital has a culture of safe and nonudgental debriefs, which follow a consistent structure to ensure that provider distress is addressed and that constructive feedback is incorporated into future events f it is clear that tea ebers have experienced distress eg, a resuscitation that ends with patient deise, it is iportant to identify this in the debrief and ensure channels exist to explore and support this further

CLINICAL ASSESSMENT OF THE ILL CHILD

 Ealuation o Es

See able 

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