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HEALTH SYSTEMS SCIENCE

SECOND EDITION

Editors-in-Chief:

Susan E. Skochelak, MD, MPH

Maya M. Hammoud, MD, MBA

Kimberly D. Lomis, MD

Editors:

Jeffrey M. Borkan, MD, PhD

Jed D. Gonzalo, MD, MSc

Luan E. Lawson, MD, MAEd

Stephanie R. Starr, MD

Table of Contents

Cover image

Title page

Copyright

Contributors

Foreword

Preface

1 What is health systems science? Building an integrated vision

I.Theneedforcurriculainhealthsystemsscience

II.Therapidlychanginghealthcareenvironment

III Clinicianreadinesstopracticeintheevolvinghealthcaresystem

IV.Thethirdmedicalscience:Healthsystemsscience

V.Healthsystemssciencecurriculardomains

VI Casestudies:Renaldiseaseandtreatment wherebasic,clinical,andhealth systemssciencemerge

VII.Professionalidentityformation

VIII Challengesforlearnerstoengagehealthsystemsscience

IX Chaptersummary

X.Overviewofbookchapters

XI.Chaptertemplate

Questionsforfurtherthought

References

Annotatedbibliography

References

2. Systems thinking in health care: Addressing the complex dynamics of patients and health systems

I Burningplatformforchangeinhealthcaredeliveryandtheneedforsystems thinking

II.Systemsthinkinginhealthcare

III.Healthcaredeliveryascomplexadaptivechallenges

IV Thehabitsofasystemsthinker

V.Applicationofsystemsthinkingtohealthcare

VI.Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

3. The health care delivery system

I.Desiredoutcomesofhealthcaredelivery

II CatalystsforchangeinUShealthcaredelivery

III Newmodelsofhealthcaredelivery

IV.Congruenceofcurrentdeliverysystemswithaccountablecareandpopulation health

V Closinggapsinthehealthcaredeliverysystem

VI.Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

4. Health care structures and processes

I Introductiontothedonabedianmodel

II.Structuresacrossthecontinuumofcare

III.Processeswithinthehealthcaresystem

IV Clinicalmicrosystems

V.Futuredirections

VI.Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

5. Value in health care

I.Introductiontovalueinhealthcare

II Knowledgeandeducationgapsinhigh-valuecare

III Definingvalue

IV.Valuefromstakeholders’perspectives

V AssessingthecurrentvalueofUShealthcare

VI Keyattributesofahigh-valuehealthcaresystem

VII.Barrierstohigh-valuecare

VIII Whatcanhealthcareprofessionalsdotopromotehigh-valuecare?

IX Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

6. Patient safety

I.Introduction

II Basicprinciplesofpatientsafety

III.Specifictypesofmedicalerrors

IV.Factorscontributingtoerror

V Communicatingwithpatientsafteradverseeventsduetomedicalerrors

VI.Secondvictims

VII.Reportingsystems—mandatoryversusvoluntary

VIII Assessmentofriskandmitigationofmedicalerrors

IX.Evaluationofnearmissesanderrors

X.Patientsafetyimprovementstrategies

XI Changingthefutureofpatientsafety

XII.Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

7. Quality improvement

I Qualityimprovementinhealthcare

II.Qualitymeasurement

III Qualityreporting

IV Qualityimprovementmethods

V.Commonqualityissuesandsuccessfulinterventions

VI.Qualityimprovementscholarship

VII Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

8. Principles of teamwork and team science

I.Introduction—teamsasacriticalaspectofhealthsystemsscience

II Thepromiseofinterprofessionalpractice

III.Teamsandcollaboration

IV.Evaluatingteamsandteamwork

V Understandinghealthsystems,systemsthinking,andteams

VI.Teamtraining

VII.Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

9. Leadership in health care

I.Introduction

II Thehealthcareleadershipimperative

III Whoarehealthcareleaders?

IV.Theimportanceofclinicianleadership

V Influentialleadershiptheories

VI Guidingprinciplesofhealthcareleadership

VII.Healthcareleadershipcompetencies

VIII.Specificattributesforhealthcareleadersindifferentsettings

IX Pathwaystoleadership

X Newleadershiproles

XI.Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

10 Clinical informatics

I.Rationaleandterminologyofclinicalinformatics

II.Useofclinicalinformaticsinhealthcaredelivery

III Secondaryuseofclinicaldata

IV.Outcomesandimplicationsofclinicalinformatics

V.Competenciesofclinicalinformatics

VI Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

11. Population health

I Introduction

II Whatispopulationhealth?

III.Whyafocusonpopulationhealth?

IV Solutionstoimprovepopulationhealth

V Futureofpopulationhealth

VI.Educationinitiativesinpopulationhealth

VII.Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

12

Structural and social determinants of health

I.Introduction

II.Casestudiesandexercise

III Howstructuralandsocialdeterminantsleadtoadversehealthoutcomes

IV.Structuraldeterminantsofhealthinequities

V.Socialdeterminantsofhealth

VI Interventionsfocusingonrootcauses

VII.Casestudyconclusions

VIII.Chaptersummary

Questionsforfurtherthought

Acknowledgments

Annotatedbibliography

References

13. Health law and ethics

I Introduction:Lawandethicsinhealthsystemschange

II Fiduciarydutyandconflictofinterest

III.Professionalself-regulationandmarketcompetition

IV Fraudandabuse

V Privacyandconfidentiality

VI.Healthinsurance

VII.Informedconsenttotreatment

VIII Medicalmalpracticeandredressingerror

IX Withholdingandwithdrawingcare

X.Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

14 Health care policy and economics

I.Introduction

II.Coreprinciplesofhealthpolicy

III Coreprinciplesofhealthcareeconomics

IV.Theoriesandhistoryofhealthcarereform

V.ThepathtotheAffordableCareAct

VI ThemajorcomponentsoftheACA

VII.TheeffectoftheACAonpatients,healthcareprofessionals,andinstitutions

VIII.Policycontroversiesandchallenges

IX Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

15. Application of health systems science competencies in patient care

I Introduction:Foundationalskillsforhealthcaredelivery

II Evidence-basedmedicine

III.Communicationskillsvianewtechnology

IV.Teamwork

V Professionalism

VI Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

16. The use of assessment to support students’ learning and improvement in health systems science

I Introduction

II.Currentattentiontohealthsystemsscienceinmajorassessmentframeworksin USmedicaleducation

III Assessmentofknowledge,skills,andpracticeperformanceinhealthsystems science

IV.Student-directedassessmentstrategiesfortheclinicalworkplace

V Assessmentofteamperformance

VI.Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

17. Looking ahead: The dynamic nature of health systems science, future trends, and the role of learners as change agents

I.Healthsystemsscience adynamic,rapidlydevelopingdomainandfieldof inquiry

II.Futuretrendsandtheirimplicationsforhealthsystemsscience

III Healthprofessionsstudentsandtraineesasmasteradaptivelearnersand changeagents

IV.Futuredirectionsforhealthsystemsscience

V Chaptersummary

Questionsforfurtherthought

Annotatedbibliography

References

Glossary

Index

Copyright

Elsevier

1600 John F. Kennedy Blvd.

Ste 1800

Philadelphia, PA 19103-2899

HEALTH SYSTEMS SCIENCE, SECOND EDITION ISBN: 978-0-323-69462-9

Copyright © 2021 by Elsevier, Inc. All rights reserved.

No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www elsevier com/permissions

This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Notice

Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds or experiments described herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.

Previous edition copyrighted 2017.

Library of Congress Control Number: 2020932480

Publisher: Elyse O’Grady

Content Development Specialist: Sara Watkins

Publishing Services Manager: Catherine Jackson

Senior Project Manager: Claire Kramer

Design Direction: Renee Duenow

Printed in Canada.

Contributors

Neera Agrwal, MD, PhD

Mayo Clinic Arizona

Chapter 5: Value in Health Care

Jose Azar, MD

Indiana University

Chapter 15: Application of Health Systems Science Competencies in Patient Care

Elizabeth Baxley, MD

American Board of Family Medicine

Chapter 12: Structural and Social Determinants of Health

Jeffrey M. Borkan, MD, PhD

Brown University

Chapter 1: What Is Health Systems Science? Building an Integrated Vision

Chapter 17: Looking Ahead: The Dynamic Nature of Health Systems Science, Future Trends, and the Role of Learners as Change Agents

Brian Clyne, MD, MHL

Brown University

Chapter 9: Leadership in Health Care

I. Glenn Cohen, JD

Harvard Law School

Chapter 13: Health Law and Ethics

Elliott J. Crigger, PhD

American Medical Association

Chapter 13/sidebar: The Code of Medical Ethics

Matthew Davis, MD, MAPP

Northwestern University Feinberg School of Medicine

Chapter 14: Health Care Policy and Economics

Ami L. DeWaters, MD, MSc

Penn State College of Medicine

Chapter 4: Health Care Structures and Processes

Jesse M. Ehrenfeld, MD, MPH

Medical College of Wisconsin School of Medicine

Chapter 6: Patient Safety

Chapter 10: Clinical Informatics

Victoria Stagg Elliott, MA

American Medical Association

Chapter 17: Looking Ahead: The Dynamic Nature of Health Systems Science, Future Trends, and the Role of Learners as Change Agents

Tonya Fancher, MD, MPH

University of California, Davis, School of Medicine

Chapter 12: Structural and Social Determinants of Health

Martha E. (Meg) Gaines, JD, LLM

University of Wisconsin Law School

Chapter 1/sidebar: Patients: The Missing Critical Voice in Health Systems Science

Paul George, MD, MHPE

Brown University

Chapter 11: Population Health

Alicia Gonzalez-Flores, MD

University of California, Davis, School of Medicine

Chapter 12: Structural and Social Determinants of Health

Jed D. Gonzalo, MD, MSc

Penn State College of Medicine

Chapter 1: What Is Health Systems Science? Building an Integrated Vision

Chapter 2: Systems Thinking in Health Care: Addressing the Complex Dynamics of Patients and Health Systems

Sara Jo Grethlein, MD

Indiana University

Chapter 9: Leadership in Health Care

Chapter 15: Application of Health Systems Science Competencies in Patient Care

Maya M. Hammoud, MD, MBA

University of Michigan and the American Medical Association

Chapter 2: Systems Thinking in Health Care: Addressing the Complex Dynamics of Patients and Health Systems

Chapter 8: Principles of Teamwork and Team Science

Iman Hassan, MD

Albert Einstein College of Medicine

Chapter 17: Looking Ahead: The Dynamic Nature of Health Systems Science, Future Trends,

and the Role of Learners as Change Agents

Karen E. Hauer, MD, PhD

University of California, San Francisco, School of Medicine

Chapter 16: The Use of Assessment to Support Students’ Learning and Improvement in Health Systems Science

William R. Hersh, MD

Oregon Health & Science University

Chapter 10: Clinical Informatics

Jason Higginson, MD, MA

Brody School of Medicine at East Carolina University

Chapter 8: Principles of Teamwork and Team Science

Allison K. Hoffman, JD

University of Pennsylvania Law School

Chapter 13: Health Law and Ethics

Linda Hofler, PhD, RN, NEA-BC

Vidant Health

Chapter 8: Principles of Teamwork and Team Science

Jill Huber, MD

Mayo Clinic

Chapter 11: Population Health

Ian Kim, MD

University of California, Davis, School of Medicine

Chapter 12: Structural and Social Determinants of Health

Russell W.H. Kridel, MD

American Medical Association

Chapter 4/sidebar: Is Private (Solo or Group) Practice for You?

Natalie Landman, PhD

Arizona State University

Chapter 5: Value in Health Care

Luan E. Lawson, MD, MAEd

Brody School of Medicine at East Carolina University

Chapter 6: Patient Safety

Kimberly D. Lomis, MD

American Medical Association

Chapter 12: Structural and Social Determinants of Health

Chapter 16: The Use of Assessment to Support Students’ Learning and Improvement in Health Systems Science

Chapter 17: Looking Ahead: The Dynamic Nature of Health Systems Science, Future Trends, and the Role of Learners as Change Agents

Barbara McAneny, MD

American Medical Association

Chapter 4/sidebar: Ask an Expert About Private Practice

Erin McKean, MD, MBA

University of Michigan

Chapter 9: Leadership in Health Care

Ryan Munyon, MD

Penn State Hershey Medical Center

Chapter 4: Health Care Structures and Processes

Chemen Neal, MD

Indiana University

Chapter 15: Application of Health Systems Science Competencies in Patient Care

Robert E. Nesse, MD

Mayo Clinic

Chapter 3: The Health Care Delivery System

Timothy Reeder, MD, MPH

Brody School of Medicine at East Carolina University

Chapter 6: Patient Safety

William M. Sage, MD, JD

University of Texas at Austin

Chapter 13: Health Law and Ethics

Mark D. Schwartz, MD

New York University Langone Health

Chapter 14: Health Care Policy and Economics

Mamta K. Singh, MD, MS

Case Western Reserve University School of Medicine

Chapter 7: Quality Improvement

Susan E. Skochelak, MD, MPH

American Medical Association

Chapter 1: What Is Health Systems Science? Building an Integrated Vision

Stephanie R. Starr, MD

Mayo Clinic

Chapter 2: Systems Thinking in Health Care: Addressing the Complex Dynamics of Patients and Health Systems

Chapter 3: The Health Care Delivery System

Sara Teasdale, MD

University of California, Davis, School of Medicine

Chapter 12: Structural and Social Determinants of Health

Elizabeth Tobin-Tyler, JD, MA

Brown University

Chapter 14: Health Care Policy and Economics

Anne Tomolo, MD, MPH

Emory University

Chapter 7: Quality Improvement

Paul F. Weber, MD, RPh, MBA

Rutgers Robert Wood Johnson Medical School

Chapter 7: Quality Improvement

Natalia Wilson, MD, MPH

Arizona State University

Chapter 11: Population Health

Daniel R. Wolpaw, MD

Penn State College of Medicine

Chapter 1: What Is Health Systems Science? Building an Integrated Vision

Therese Wolpaw, MD, MHPE

Penn State College of Medicine

Chapter 17: Looking Ahead: The Dynamic Nature of Health Systems Science, Future Trends, and the Role of Learners as Change Agents

Steven Yuen, MD

Barrow Neurological Institute

Chapter 5: Value in Health Care

Foreword

Technology is changing our world and the practice of medicine at a pace unmatched in human history. Yet for all the societal advancements and technological marvels over the last century, the way we train and educate new doctors has changed little.

Medical school curricula have, of course, expanded over the years to include important new medical breakthroughs and discoveries, but their focus and overall structure remain stubbornly captive to early 20th-century thinking. The result is an ever-widening gap between how physicians in the United States are trained and educated and the realities of the modern health care environment.

Recognizing this gap, the American Medical Association (AMA) in 2013 set out to transform and modernize medical education in this country by creating, and providing funding for, a diverse network of medical schools to innovate, share practices, and push the boundaries of traditional medical education. In short, we inspired them to think big.

This reinvention of the medical school of the future was part of a strategic realignment at the AMA to further our mission to promote the art and science of medicine and the betterment of public health. The other pillars in our renewed strategic focus areas include creating the tools and resources to help physicians thrive in modern health care and developing new and better approaches to combat America’s growing health epidemic of chronic disease. Many opportunities for innovation were identified in these efforts; to address these, an AMA innovation ecosystem was created with nodes, including a Chicago-based health care start-up incubator (MATTER) and a Silicon Valley–based innovation company (Health2047) Together, these initiatives are foundational to the AMA’s work to lead meaningful innovation and enable a better health care system for patients, physicians, and the nation.

Each of these three core focus areas is shaping health care today and long into the future. However, it is our efforts around medical education, our exciting Accelerating Change in Medical Education initiative, that may ultimately be the most far-reaching and impactful

Now, more than 5 years into this program, the schools in our Accelerating Change in Medical Education Consortium regularly meet, develop, and share their curricular innovations, which, when aggregated, form a vision of the medical schools of the future: one that measures competency; one that responds to the needs of chronic disease through team-based care approaches, greater continuity, and more outpatient exposure;

and one that adopts new technologies for education and creates new fields of medical science.

These 37 consortium members are schools that will do more than prepare young doctors to care for patients. They will prepare physicians for a lifetime of training and learning. They will prepare them to take leadership roles in their practices, while also exploring the most innovative ways to care for patients, populations, and communities

The emergence of health systems science will be a key component of the medical schools of the future, bridging the study of basic and clinical sciences and giving new physicians a broad view of the societal influences and administrative challenges that sometimes complicate patient care. Health systems science is that window into the lives of our patients and our communities that makes us more effective, compassionate, and knowledgeable doctors This offering has been well received, and thus we have produced this the second edition.

It is important to remember that the history of medicine is the history of innovation and change. For nearly 170 years, physicians have relied on the AMA to keep them informed, engaged, and at the forefront of technological advancements so that they can better meet the ever-changing needs of their patients With the innovations, tools, and products emerging from the AMA strategic arcs, the AMA is positioning itself as the physician’s powerful ally in patient care.

By reinventing medical education and encouraging our doctors of tomorrow to rethink how we deliver care in this new digital age of medicine, the AMA is bringing the future of our profession into sharper focus and improving health care for generations to come

Preface

Susan E. Skochelak, MD, MPH, Maya M. Hammoud, MD, MBA, Kimberly D. Lomis, MD, Jeffrey M. Borkan, MD, PhD, Jed D. Gonzalo, MD, MSc, Luan E. Lawson, MD,

Since the first edition of this textbook was published in 2017, health systems science has increasingly become integrated into medical education. Competency in this realm ensures that medical school graduates and those graduating from other health professions schools can effectively translate and apply the basic and clinical sciences and meaningfully improve patients’ health at the individual, community, and population levels.

The concept of health systems science as a required third pillar of medical education emerged after long debate among members of the American Medical Association (AMA) Accelerating Change in Medical Education Consortium This consortium was formed by the AMA in 2013 after awarding initial grants to 11 medical schools from across the country. The consortium is a unique, innovative collaboration that allows for the sharing and dissemination of groundbreaking ideas and projects. In 2016, the AMA awarded grants to another 21 schools. In 2019, five more schools were added. The consortium represents one-fifth of allopathic and osteopathic medical schools. These schools are delivering forward-thinking educational experiences to nearly 24,000 medical students students who will provide care to a potential 41 million patients annually.

More than a century ago, the Flexner report recommended significant changes to increase the scientific rigor and standardization of medical school curricula. The consortium recommends health systems science as the third critical science required of physicians and other health professionals to prepare them for their future roles and to enable them to have the greatest impact on the health of patients and society. Basic science is about understanding the mechanisms and functions of the human body. Clinical science is focused on diagnosis, treatment, and prevention obtaining histories, examining patients, and choosing interventions that maintain health, ameliorate decline, and maximize the function of the human body Even if basic and clinical sciences are expertly learned and executed, without health systems science physicians cannot realize their full potential impact on patients’ health or on the health of the population. Health systems science includes all the factors in the lives of patients that influence their well-being (e.g., social determinants of health and health disparities); the structures and processes of the health system itself (e g , patient access, financing,

quality improvement); societal factors (e g , health policy and advocacy); communication (e.g., verbal, written, team); and information technology (e.g., electronic health records, search engines). Incorporating an understanding of health systems science in medical education will improve the quality and value of care that physicians and other health professionals deliver and that patients and communities experience.

There are other textbooks that explore health systems science from the perspective of managers, administrators, or policymakers, and there are other textbooks that delve more fully into the subjects of each individual chapter of this book. This textbook was the first aiming to define the canon of health systems science and elucidate the health systems science framework for educating health care professionals. We hope it will serve as the base for ever-expanding advancements in the teaching of health systems science and the incorporation of health systems science into practice

Although this textbook seeks to define health systems science, it is important to note that health systems science is still an emerging discipline. We know health systems science is a dynamic, rapidly changing field. Our intention is that this textbook will serve as a platform on which changes can be made over time. We are just at the beginning of our health systems science journey

The editors and authors would like to thank the members of the AMA Accelerating Change in Medical Education Consortium for their tireless work to transform medical education by implementing health systems science as well as other significant innovations. This textbook is dedicated to the patients, communities, and populations we serve.

What is health systems science? Building an integrated vision

CHAPTER OUTLINE

I.TheNeedforCurriculainHealthSystemsScience,2

II.TheRapidlyChangingHealthCareEnvironment,2

A.HealthCarePolicyInitiatives,3

B.PaymentReformandValue,3

C.HealthCareDeliverySystemInnovationandTransformation,3

D.TransformativeHealthInformationTechnology,Data,andInformatics,4

III.ClinicianReadinesstoPracticeintheEvolvingHealthCareSystem,5

IV.TheThirdMedicalScience:HealthSystemsScience,5

A.TheCurrentTwo-PillarModelofMedicalEducation,5

B.ConceptualizingHealthSystemsScience The“ThirdPillar”ofMedical Education,5

C.WhatIsHealthSystemsScience?,6

D.Engel’sBiopsychosocialModel,7

E.HowHealthSystemsScienceIsMoreThantheIndividualComponents, 7

F.HowHealthSystemsScienceIsConnectedtotheTripleandQuadruple Aims,8

V.HealthSystemsScienceCurricularDomains,8

A.CoreFunctionalDomains,8

1. Patient, Family, and Community, 8

2. Health Care Structure and Process, 8

3. Health Care Policy and Economics, 9

4. Clinical Informatics and Health Technology, 9

5. Population, Public, and Social Determinants of Health, 9

6. Value in Health Care, 10

7. Health System Improvement, 10

B.FoundationalDomains,10

1. Change Agency, Management, and Advocacy, 10

2. Ethics and Legal, 10

3. Leadership, 10

4. Teaming, 11

C.LinkingDomain:SystemsThinking,11

VI.CaseStudies:RenalDiseaseandTreatment WhereBasic,Clinical,and HealthSystemsScienceMerge,11

VII.ProfessionalIdentityFormation,12

A.Physician-CentricRoleIdentity,13

B.Patient-Centered,SystemsRoleIdentity,14

VIII.ChallengesforLearnerstoEngageHealthSystemsScience,15

A.AddresstheHiddenCurriculum,15

B.DemonstratethePotentialforAddingValuetothePractice,15

C.ImprovetheUndergraduate-to-GraduateMedicalEducationTransition, 16

IX.ChapterSummary,16

X.OverviewofBookChapters,17

XI.ChapterTemplate,17

In this chapter

For over 100 years, medical education has relied upon two pillars for training physicians ready to practice medicine: basic science and clinical science. Health systems science—the understanding of how care is delivered, how health care professionals work together to deliver that care, and how the health system can improve patient care and health care delivery has been part of the hidden curriculum or taught as part of elective courses. There have been many attempts to formalize the role of health systems science in medical school curriculum and make it the third pillar of physician education. Progress toward that goal is steadily advancing.

Health systems science is intimately intertwined with the two pillars of medical education but is also a subject in its own right requiring study by medical students. Additionally, physicians’ roles in the health care system are changing significantly, and physicians need to understand health systems science in order to fulfill their evolving roles. Health systems science competencies extend

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