Encyclopedia of biomedical engineering (vol. 1-3) min wang - The ebook with all chapters is availabl

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ENCYCLOPEDIAOF BIOMEDICALENGINEERING

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EDITORINCHIEF

Dr.RogerNarayanisaprofessorintheJointDepartmentofBiomedicalEngineeringatthe UniversityofNorthCarolinaandNorthCarolinaStateUniversity.Heisanauthorofover200 publicationsaswellasseveralbookchaptersonprocessing,characterization,andmodelingofbiologicalandbiomedicalmaterials.Dr.Narayanhaseditedseveralbooks,including BiomedicalMaterials,PrintedBiomaterials,ComputerAidedBiomanufacturing,Diamond-BasedMaterialsforBiomedical Applications,MedicalBiosensorsforPointofCare(POC)Applications,MonitoringandEvaluationofBiomaterialsandtheirPerformanceInVivo,Nanobiomaterials:NanostructuredMaterialsforBiomedicalApplications,andtheASMHandbookonMaterialsforMedicalDevices.Hehaspreviouslyservedaschairofthe FunctionalMaterialsDivisionofTheMinerals,Metals&MaterialsSocietyandiscurrentlychair-elect oftheBioceramicsDivisionofAmericanCeramicsSociety.Dr.Narayanhasreceivedseveralhonors forhisresearchactivities,includingtheNorthCarolinaStateUniversityAlcoaFoundationEngineeringResearchAchievementAward,theNorthCarolinaStateUniversitySigmaXiFaculty ResearchAward,theUniversityofNorthCarolinaJefferson-PilotFellowshipinAcademicMedicine, theNationalScienceFacultyEarlyCareerDevelopmentAward,theOfficeofNavalResearchYoung InvestigatorAward,theAmericanCeramicSocietyRichardM.FulrathAward,theRoyalAcademyofEngineeringDistinguishedVisiting Fellowship,andTMSBrimacombeMedal.HehasservedasFulbrightScholarattheUniversityofOtago,theNationalPolytechnicInstitute (MexicoCity),andtheUniversityofSaoPaulo.HehasbeenelectedasFellowofASMInternational,theAmericanAssociationforthe AdvancementofScience,theAmericanCeramicSociety,andtheAmericanInstituteforMedicalandBiologicalEngineering.

EuropeanResearchCouncilin2010;andhewaselectedmemberoftheYoungAcademyoftheAustrianAcademyofSciencesin 2011.In2012,hewasrewardedtheprestigiousWalterL.HuberResearchPrizeoftheASCE,forhiscontributionstothemicroporomechanicsofhierarchicalgeomaterialsandbiomaterials;hewaselectedFellowofEMIin2014andwascorecipientofthe2017 KajalMallickMemorialAwardoftheInstitutionofCivilEngineers(UnitedKingdom).

SriKrishnan

Sridhar(Sri)KrishnanreceivedB.E.degreeinElectronicsandCommunicationEngineering fromtheCollegeofEngineering,Guindy,AnnaUniversity,Chennai,India,in1993,and M.Sc.andPh.D.degrees(withstudentfellowshipfromAlbertaHeritageFoundationfor MedicalResearch)inElectricalandComputerEngineeringfromTheUniversityofCalgary, Calgary,Alberta,Canada,in1996and1999,respectively.SriKrishnanjoinedRyersonUniversityinJuly1999andiscurrentlyaProfessorintheDepartmentofElectricalandComputer Engineering.SinceJuly2011,heisanAssociateDean(Research,DevelopmentandExternal Partnerships)fortheFacultyofEngineeringandArchitecturalScience.HeisalsotheCodirectoroftheInstituteforBiomedicalEngineering,ScienceandTechnology(iBEST)andan affiliatescientistattheKeenanResearchCentreinSt.Michael’sHospital,Toronto.

SinceJanuary2002SriKrishnanheldvariousadministrativeleadershippositionsinthe DepartmentofElectricalandComputerEngineeringandtheFacultyofEngineeringand ArchitecturalScience.In2010–2011,SriKrishnanheldVisitingAppointmentsinUniversity ofRennes1(France),GrenobleInstituteofTechnology(France)andIndianInstituteofTechnology(Madras).SriKrishnanisaregisteredprofessionalengineerintheProvinceofOntarioandisaseniormemberofIEEE(EMBS andSPsocieties).HewastheFoundingChair(2005–2015)ofIEEESignalProcessingSociety,TorontoSectionandRegion7(Canada),andaFoundingMemberoftheIEEEEngineeringinMedicineandBiologySociety,TorontoSection.Hecurrentlyservesas aTechnicalCommitteeMember(BiomedicalSignalProcessing)ofIEEEEMBS.

SriKrishnanheldtheCanadaResearchChairposition(2007–2017)inBiomedicalSignalAnalysis.SriKrishnanhassuccessfully supervised/trained10postdocfellows,10Ph.D.,30Masters(thesis),9Masters(project),42RAs,and20VisitingRAs.SriKrishnan’ s researchinterestsincludeadaptivesignalrepresentationsandanalysisandtheirapplicationsinbiomedicine,multimedia(audio), andbiometrics.Hehaspublished295papersinrefereedjournalsandconferences, filed10inventiondisclosures,andhasoneUS patent.Hehaspresentedkeynote/plenary/invitedtalksinmorethan35internationalconferencesandworkshops.SriKrishnanalso servesasareviewer,committeemember,andchairformanyinternationalconferences,journals,andgrantingbodies.SriKrishnan’ s academicinterestsinclude(interdisciplinary)curriculumdesign,experientiallearning,andinnovation.SriKrishnanservesinthe advisoryboardsofresearchinstitutes,innovationcenters,incubatorzones,andbusinessorganizations.

SriKrishnanisarecipient/awardedOutstandingCanadianBiomedicalEngineerAward2016;CertificateofAppreciationfrom PEOYorkChapter2016;FellowofCanadianAcademyofEngineeringin2014;2014ExemplaryServiceAwardfromIEEEToronto Section;2014CertificateofMeritfromIEEESignalProcessingSociety;2013AchievementinInnovationAwardfromInnovateCalgary;2011SarwanSahotaDistinguishedScholarAward;2011CertificateofAppreciationfromIEEESignalProcessingSociety;2010 ShastriVisitingProfessorship;2010FrenchEmbassyVisitingResearcher;2008OntarioResearchInnovationAwardfromBiodiscoveryToronto;2007CanadianEngineers’ YoungEngineerAchievementAwardfromEngineers’ Canada;2006NewPioneers AwardinScienceandTechnology;2006SouthAsianCommunityAchieverAward;2006IEEETorontoSectionBestChapterChair Award;2005IEEEAESSBestChapterChairAward;2005IEEECertificateofAppreciationfromSixSocieties;SixBestResearchPaper AwardscoauthoredwithhisgraduatestudentsinInternationalConferences;and2005FEASResearchExcellenceAward.

CatoLaurencin

CatoT.Laurencin,M.D.,Ph.D.istheUniversityProfessoratUCONN.HeistheeighthdesignatedinUCONN’shistory.HeisProfessorofChemicalEngineering,ProfessorofMaterials ScienceandEngineering,andProfessorofBiomedicalEngineering,andtheVanDusenDistinguishedEndowedProfessorofOrthopaedicSurgery.HedirectstheInstituteforRegenerative EngineeringandtheRaymondandBeverlySacklerCenterattheUniversityofConnecticut.

Dr.LaurencinearnedhisB.S.E.degreeinChemicalEngineeringfromPrincetonUniversity. HeearnedhisPh.D.inBiochemicalEngineering/BiotechnologyfromtheMassachusettsInstituteofTechnologywherehewasnamedaHughHamptonYoungFellow.Atthesametime,he earnedhisM.D.,MagnaCumLaudefromtheHarvardMedicalSchoolwherehereceivedthe RobinsonAwardforSurgery.

Dr.Laurencinisanexpertinbiomaterials,nanotechnology,stemcellscience,and,thenew fieldhehaspioneered,RegenerativeEngineering.HeisafellowofAmericanInstituteofChemical

Engineersandwasnamedoneofthe100EngineersoftheModernErabytheAICHE.HereceivedthePercyJulianMedalfromNational OrganizationofBlackChemistsandChemicalEngineers,andthePierreGallettiAwardfromtheAmericanInstituteofMedicaland BiologicalEngineering.HehasreceivedtheNIHDirector’sPioneerAwardandtheNationalScienceFoundationEmergingFrontiers inResearchandInnovationAwardforhisresearchinRegenerativeEngineering.

Dr.LaurencinisanelectedmemberoftheNationalAcademyofEngineering,theNationalAcademyofMedicine,theIndian NationalAcademyofEngineering,theIndianNationalAcademyofSciences,andtheAfricanAcademyofSciences.HeisanacademicianandforeignmemberoftheChineseAcademyofEngineering.

Dr.Laurencinhastwoawardsnamedinhishonor.TheW.MontagueCobbInstituteandtheNationalMedicalAssociationestablishedtheCatoT.LaurencinLifetimeResearchAchievementAward,whiletheSocietyforBiomaterialsestablishedTheCatoT.Laurencin,M.D.,Ph.D.TravelFellowshipAward.

Dr.LaurencinreceivedthePresidentialFacultyFellowAwardfromPresidentBillClintonandthePresidentialAwardforExcellenceinScience,Mathematics,andEngineeringMentoringfromPresidentBarackObama.HeistherecipientoftheNationalMedal ofTechnologyandInnovation,America’shighestawardfortechnologicalachievementfromPresidentBarackObamainceremonies attheWhiteHouse.

Prof.DiegoMantovaniisthedirectorofLaboratoryforBiomaterialsandBioengineeringat LavalUniversity,inCanada,andseniorscientistoftheRegenerativeMedicineDivisionof theQuebecUniversityHospitalResearchCentre.Hereceivedhisdoctoraldegreejointly fromUniversityofTechnologyofCompiègne,France,andLavalUniversityin1999andhis jointDiplomainEngineeringfromPolitecnicodiMilanoandtheUniversityofTechnology ofCompiegne,France,in1993.Afteranindustrialpostdoc(1999),hebecomesprofessor atLavalUniversitySchoolofScienceandEngineeringin2000.SincethebeginningheestablishedisLaboratoryattheUniversityHospitalResearchCenterinQuebecCity.Withinhis team,researchesfocusonsurfacemodificationsbyplasma,thinpolymerfunctional films, cell–materialsinteractions,degradablemetals,scaffolds,andbioreactorsforthereplacement andregenerationofcardiovasculartissue.Hehasauthoredmorethan260originalarticles, holds5patents,andpresentedmorethan185keynotes,invitedandseminarlecturesworldwide.HisH-indexis43(June2018),andhisworkswerecitedmorethan7000times.Hewas PresidentoftheCanadianSocietyforBiomaterials(2008 –2009),andExecutiveCochairof theWorldBiomaterialsCongressin2016inMontreal,Canada.In2012,hewaselectedFellowoftheWorldBiomaterialsScience andEngineeringSociety.Since2012,heistheholderoftheCanadaResearchChair1inBiomaterialsandBioengineeringforthe InnovationinSurgery.HewasmemberofadhocpanelsatFDA,ISO,andHealthCanadaandmemberofanumberoffunding, regulatoryandscientificcommitteesworldwide.HeisAdjunctProfessoratPolitecnicodiMilanoandUniversitadelPiemonteOrientaleinItaly,aswellasattheVelloreInstituteofTechnology,inIndia.Hewasinvitedprofessorinseveraluniversitiesworldwide, includingCampinas,Brasil(2012–2015),Bologna(2015),Bordeaux(2014),SiaoTongWest,China(2012),Cergy-Pontoise (2012),ParisTech(2011),BuenosAires(2010),Namur,Belgium(2008),TorVergata,Italy(2007),Ankara,Turkey(2006),and others.Heismemberoftheeditorialboardof fivescientificjournalsinthe fieldandoftheadvisoryboardofthreemedicaldevices consortiaworldwide.

WilliamZRymer

ProfessorWilliamZRymerisProfessorofPhysicalMedicineandRehabilitationandPhysiologyattheRehabilitationInstituteofChicago,Chicago,IL,UnitedStates.Hisfocusof workincludespathophysiology,stroke,spinalcordinjury,spinalcircuits,biomedicalengineering,andneuralsignalprocessing.

PankajVadgama

PankajVadgamaqualifiedinDegreeinMedicineandtheninChemistryattheUniversityof NewcastleuponTyne,UnitedKingdom,withaFirstClassHonorsBSc.Heisachemical pathologist,becomingaFellowoftheRoyalCollegeofPathology.HecompletedhisPh.D. onmedicalbiosensorsasanMRCFellowatNewcastle,andwhilethere,hewasmadeDirector oftheBiosensorsGroupandlaterappointedasProfessorofClinicalBiochemistryatthe UniversityofManchester,subsequentlybecomingResearchDeanfortheFacultyofMedicine. HewasappointedDirectoroftheInterdisciplinaryResearchCentreinBiomedicalMaterialsat QueenMary,UniversityofLondonandwas,untilrecently,HeadoftheDepartmentofClinicalBiochemistry,BartsHealthNHSTrust.Hismaininterestsarevariouslybiosensors, appliedbioelectrochemistry,point-of-caretesting,andmembranetechnology.Hehaspublishedover200papers.HeisalsoFellowoftheRoyalSocietyofMedicine,InstituteofPhysics, RoyalSocietyofChemistry,theInstituteofMaterialsMineralsandMining,andtheRoyal SocietyofBiology.HewasgiventheFoundationAwardoftheAssociationofClinical BiochemistryandLaboratoryMedicine,hasbeenaSandozLectureroftheBritishGeriatric Society,anddeliveredtheLatnerlectureattheUniversityofNewcastle.Hehasservedon variousUKResearchCouncilgrantsawardcommitteesandisatpresentmemberoftheInstituteofMaterialsMineralsandMiningSmartMaterialsandNanoCommitteesandthe BiomedicalMaterialsApplicationDivision.HesitsonvariousBSIcommitteesandwasChairoftheISOsubpanelonnanomedicine nomenclature.HesitsonvariouseditorialboardsandisEditorinChiefof Bioelectrochemistry.HeisDeputyChairoftheCouncilfor theFrontiersofSciencebasedinUgandadirectedatresearchtraininginEastAfrica.

MinWang

MinWangisaFullProfessoratTheUniversityofHongKong(HKU),andasProgramme Director(2013–2018),hehasledHKU’sMedicalEngineeringProgramme(whichisretitled to “BiomedicalEngineeringProgramme” in2018).Hehasworkedinuniversitiesinthe UnitedKingdom(1991–1997),Singapore(1997–2002),andHongKong(2002–Present) andhasbeenaGuestProfessororAdjunctProfessorofseveraluniversitiesinmainlandChina (ShanghaiJiaoTongUniversity,ZhejiangUniversity,TianjinUniversity,SouthwestJiaotong University,etc.).HewasawardedBSc(1985)andPh.D.(1991),bothinMaterialsScienceand Engineering,byShanghaiJiaoTongUniversityandUniversityofLondon,respectively.Heis acharteredengineer(CEng,1995;UK)andcharteredscientist(CSci,2005;UK).HeisanelectedfellowofprofessionalsocietiesintheUnitedKingdom,HongKong,UnitedStates,and internationally(FIMMM,2001; FIMechE,2007; FHKIE,2010; FBSE,2011; FAIMBE,2012; WACAcademician,2013).Since1991,hehasbeenconductingresearchinbiomaterialsand tissueengineeringanddevelopingnewbiomaterialsusingthecomposite/hybridization approach.HewasafoundingmemberofUK’sInterdisciplinaryResearchCentre(IRC)in BiomedicalMaterialsattheUniversityofLondon.Hisbiomaterialsresearchhascovered metals,polymers,ceramics,andcompositesandincludessurfacemodi ficationofmaterialsorscaffolds.Inrecentyears,hehas focusedonnanobiomaterials,electrospinning,and3Dprinting.Heandhisresearchstaff/studentshavewonmanyawardsatinternationalconferences.Hehasauthoredalargenumberofresearchpapersaswellasmanybookchapters.Hisresearchhasbeen widelycitedbyotherresearchersaroundtheworld.Hehasgivenmanyconferencepresentations,includingmorethan150invited talksatinternationalconferences.Hehasalsogivenmorethan110seminarsinuniversities,researchinstitutes,andhospitalsin Europe,NorthAmerica,Asia,andAustralia.HehasbeenChairman/Organizerofmanyconferencesandhasservedincommittees ofmorethan70internationalconferences.HeistheFoundingSeriesEditorof SpringerSeriesinBiomaterialsScienceandEngineering booksandhasbeenEditor,AssociateEditor,ormemberoftheEditorialBoardof20international,printedjournals,including InternationalMaterialsReviews, CompositesScienceandTechnology, SurfaceandCoatingsTechnology, JournalofMaterialsScience:Materialsin Medicine,and JournaloftheRoyalSocietyInterface.Hehasactedasarefereeformorethan110internationaljournalsinthe fieldsof materialsscienceandengineering,biomaterialsandtissueengineering,physics,chemistry,medicine,dentistry,medicaldevices, biofabrication,nanoscience,nanotechnology,and3Dprinting.Hehasbeenactiveinprofessionalsocietyactivitiesandhasserved invariousrolesinthesesocieties.HewasChairmanoftheBiomedicalDivisionofHongKongInstitutionofEngineers(HKIE).He serves/hasservedintheNominationCommitteeofWorldAcademyofCeramics(WAC)andtheICF-BSESteeringCommitteeofthe InternationalCollegeofFellowsoftheInternationalUnionofSocietiesforBiomaterialsScienceandEngineering(IUS-BSE).Hehas beenanelectedCouncilMemberofChineseSocietyforBiomaterials,HongKongInstitutionofEngineers,AsianBiomaterialsFederation,WorldAssociationforChineseBiomedicalEngineers(WACBE),andAdministrativeCouncilofInternationalFederationfor MedicalandBiologicalEngineering(IFMBE).(http://web.hku.hk/ memwang/).

CONTRIBUTORSTOVOLUME1

TylerAckley

UConnHealth,Farmington,CT,UnitedStates

Ra

fiqAhmad

ChonbukNationalUniversity,Jeonju-si,Jeollabuk-do, RepublicofKorea

SongIhAhn

GeorgeW.WoodruffSchoolofMechanicalEngineering, WallaceH.CoulterDepartmentofBiomedical Engineering,InstituteforElectronicsand Nanotechnology,ParkerH.PetitInstitutefor BioengineeringandBioscience,GeorgiaInstituteof Technology,Atlanta,GA,UnitedStates

KhiamAikKhor

NanyangTechnologicalUniversity, Singapore

JamesMAnderson

CaseWesternReserveUniversity,Cleveland,OH, UnitedStates

LaviniaCosminaArdelean

“VictorBabes” UniversityofMedicineandPharmacy Timisoara,Timisoara,Romania

AAtala

WakeForestBaptistMedicalCenter,Winston Salem, NC,USA

STAvecilla

NewYorkPresbyterianHospital,WeillCornellMedical College,NewYork,NY,USA

HaniAAwad UniversityofRochester,Rochester,NY,UnitedStates

BesimBen-Nissan UniversityofTechnologySydney,Sydney,NSW, Australia

SerenaBest UniversityofCambridge,Cambridge,UnitedKingdom

AldoRBoccaccini UniversityofErlangen-Nuremberg,Erlangen,Germany

MBohner

RMSFoundation,Bettlach,Switzerland

MEBronner

CaliforniaInstituteofTechnology,Pasadena,CA,USA

AshleyCBrown

NorthCarolinaStateUniversityandUniversityofNorth CarolinaatChapelHill,Raleigh,NC,UnitedStates; andNorthCarolinaStateUniversity,Raleigh,NC, UnitedStates

ArnaudBruyas

StanfordUniversity,Stanford,CA,UnitedStates

SABusch

Athersys,Inc.,Cleveland,OH,USA

RuthCameron UniversityofCambridge,Cambridge,UnitedKingdom

SophieCazalbou

UMR5085UPS-INPT-CNRS,Toulouse,France

PaulZChen

UniversityofWaterloo,Waterloo,ON,Canada

ShiyuCheng

BeijingEngineeringResearchCenterfor BioNanotechnologyandCASKeyLaboratoryfor BiomedicalEffectsofNanomaterialsandNanosafety, CASCenterforExcellenceinNanoscience,National CenterforNanoScienceandTechnology,Beijing,P.R. China

DanielChester

NorthCarolinaStateUniversityandUniversityofNorth CarolinaatChapelHill,Raleigh,NC,UnitedStates; andNorthCarolinaStateUniversity,Raleigh,NC, UnitedStates

AndyHChoi UniversityofTechnologySydney,Sydney,NSW, Australia

EzharulHoqueChowdhury MonashUniversity,Clayton,VIC,Australia

StefaniMazzitelli

UniversityofFerrara,Ferrara,Italy

RMorita

TokyoUniversityofScience,Noda,Chiba,Japan

MahboobMorshed IndependentUniversity,Dhaka,Bangladesh

AmirNajarzadeh

UniversityofKentucky,Lexington,KY,UnitedStates

MNakashima

DepartmentofDentalRegenerativeMedicine,Centerof AdvancedMedicineforDentalandOralDiseases, NationalCenterforGeriatricsandGerontology, ResearchInstitute,Obu,Japan

ClaudioNastruzzi

UniversityofFerrara,Ferrara,Italy

InnChuanNg

NationalUniversityofSingapore,Singapore

DHNguyen

ShileyEyeCenterandInstituteforGenomicMedicine, UniversityofCaliforniaatSanDiego,LaJolla,CA,USA

MitsuoNiinomi

TohokuUniversity,Sendai,Japan;OsakaUniversity, Osaka,Japan;MeijoUniversity,Nagoya,Japan;and NagoyaUniversity,Nagoya,Japan

BridgetOei

UConnHealth,Farmington,CT,UnitedStates

AnuragOjha

UniversityofConnecticut,Storrs,CT,UnitedStates

MOshima

TokyoUniversityofScience,Noda,Chiba,Japan

HOuyang

ShileyEyeCenterandInstituteforGenomicMedicine, UniversityofCaliforniaatSanDiego,LaJolla,CA,USA

Chi-ChunPan

StanfordUniversity,Stanford,CA,UnitedStates

PornteeraPawijit

NationalUniversityofSingapore,Singapore

AuraPenalosa

UniversityofConnecticut,Storrs,CT,UnitedStates

DPergament

CaseWesternReserveUniversitySchoolofLaw, Cleveland,OH,USA;andChildren’sLawGroup,LLC, Chicago,IL,USA

ElenaPirogova

RMITUniversity,Melbourne,VIC,Australia

DavidAPuleo

UniversityofKentucky,Lexington,KY,UnitedStates

ZichenQian

MichiganTechnologicalUniversity,Houghton,MI, UnitedStates

RuQingYu

TheUniversityofHongKong,HongKong

DanielRadke

MichiganTechnologicalUniversity,Houghton,MI, UnitedStates

PRajan

TheScrippsResearchInstitute,LaJolla,CA,USA

SahilKumarRastogi CarnegieMellonUniversity,Pittsburgh,PA,United States

MuhammadYRazzaq

InstituteofBiomaterialScienceandBerlinBrandenburg CenterforRegenerativeTherapies,Teltow,Germany

LucienReclaru

VVSA,branchofRichemontInternationalSAVarinor Innovation,Delémont,Switzerland

MarkusReinthaler InstituteofBiomaterialScienceandBerlinBrandenburg CenterforRegenerativeTherapies,Teltow,Germany

NicholasPRhodes UniversityofLiverpool,Liverpool,UnitedKingdom

KelseyRichard UConnHealth,Farmington,CT,UnitedStates

RGRichards

AOResearchInstitute,Davos,Switzerland

AaqilRifai

RMITUniversity,Melbourne,VIC,Australia

StevenARoss UniversityofGreenwich,Greenwich,UnitedKingdom

MSaito TokyoUniversityofScience,Noda,Chiba,Japan

NaseemSardashti UniversityofConnecticutHealth,Farmington,CT, UnitedStates;andUniversityofConnecticut,Storrs, CT,UnitedStates

MarkSchröder InstituteofBiomaterialScienceandBerlinBrandenburg CenterforRegenerativeTherapies,Teltow,Germany

NikolaosScoutaris UniversityofGreenwich,Greenwich,UnitedKingdom

SwaminathanSethuraman

SASTRADeemedUniversity,Thanjavur,India

JeongEunSong

ChonbukNationalUniversity,Jeonju-si,Jeollabuk-do, RepublicofKorea

AlexanderMartinStahl

StanfordUniversity,Stanford,CA,UnitedStates

TeagenStedman UniversityofConnecticutHealth,Farmington,CT, UnitedStates

AnuradhaSubramanian

SASTRADeemedUniversity,Thanjavur,India

MillicentOSullivan UniversityofDelaware,Newark,DE,UnitedStates

HaoranSun

TheUniversityofHongKong,Pokfulam,HongKong

MitchTahtinen

MichiganTechnologicalUniversity,Houghton,MI, UnitedStates

JordonTan

TemasekPolytechnic,Singapore

AETing

Athersys,Inc.,Cleveland,OH,USA

NirmalyaTripathy UniversityofWashington,Seattle,WA,UnitedStates

TTsuji

TokyoUniversityofScience,Noda,Chiba,Japan;and OrganTechnologiesInc.,Tokyo,Japan

NTurovets

UniversityofCalifornia,Irvine,CA,USA

MorganAUrello UniversityofDelaware,Newark,DE,UnitedStates

AntonioValdevit

StevensInstituteofTechnology,Hoboken,NJ,United States;andSEALimited,Columbus,OH,UnitedStates

NandakumarVenkatesan UniversityofKentucky,Lexington,KY,UnitedStates

ChongWang

DongguanUniversityofTechnology,Dongguan,China

GuifangWang

MichiganTechnologicalUniversity,Houghton,MI, UnitedStates

JingYiWang

TheUniversityofHongKong,HongKong

MianWang

NortheasternUniversity,Boston,MA,UnitedStates

MinWang

TheUniversityofHongKong,Pokfulam,HongKong QiongWang

TheUniversityofBritishColumbia,Vancouver,BC, Canada

RizhiWang

TheUniversityofBritishColumbia,Vancouver,BC, Canada

ThomasJWebster

NortheasternUniversity,Boston,MA,UnitedStates; andWenzhouMedicalUniversity,Wenzhou,China

RachelLWilliams UniversityofLiverpool,Liverpool,UnitedKingdom

ChristianWischke

InstituteofBiomaterialScienceandBerlinBrandenburg CenterforRegenerativeTherapies,Teltow,Germany

ManSangWong

TheHongKongPolytechnicUniversityofHongKong, HungHom,HongKong

YinXiao

QueenslandUniversityofTechnology,Brisbane,QLD, Australia

YunzhiYang

StanfordUniversity,Stanford,CA,UnitedStates

HanryYu

NationalUniversityofSingapore,Singapore;Agencyfor Science,TechnologyandResearch(A*STAR), Singapore;BioSyM,Singapore-MITAlliancefor ResearchandTechnology,Singapore;andNanfang Hospital,SouthernMedicalUniversity,Guangzhou, China

XiaojunYu

StevensInstituteofTechnology,Hoboken,NJ,United States

KZhang

ShileyEyeCenterandInstituteforGenomicMedicine, UniversityofCaliforniaatSanDiego,LaJolla,CA,USA

FengZhao

MichiganTechnologicalUniversity,Houghton,MI, UnitedStates

QilongZhao

ShenzhenInstitutesofAdvancedTechnology,Chinese AcademyofSciences,Shenzhen,China

LiWuZheng

PrincePhilipDentalHospital,TheUniversityofHong Kong,HongKong

WenfuZheng

BeijingEngineeringResearchCenterfor BioNanotechnologyandCASKeyLaboratoryfor BiomedicalEffectsofNanomaterialsandNanosafety, CASCenterforExcellenceinNanoscience,National CenterforNanoScienceandTechnology,Beijing,P.R. China

YuZheng TheHongKongPolytechnicUniversityofHongKong, HungHom,HongKong

YinghongZhou QueenslandUniversityofTechnology,Brisbane,QLD, Australia

HalaZreiqat UniversityofSydney,Sydney,NSW,Australia

Micro fluidicsforBiomedicalApplications368 ShiyuCheng,JinqiDeng,WenfuZheng,andXingyuJiang

Organs-on-Chips

384 YunkiLee,SongIhAhn,andYongTaeKim

Shape-MemoryPolymerMedicalDevices394 MuhammadYRazzaq,MarkusReinthaler,MarkSchröder,ChristianWischke,andAndreasLendlein

RegenerativeEngineering

AdultBoneMarrow-DerivedStemCells:ImmunomodulationintheContextofDiseaseandInjury406 AETingandSABusch

AssessmentofCellularResponsesofTissueConstructsinvitroinRegenerativeEngineering414 MargaretATFreeberg,JacobGKallenbach,andHaniAAwad

AssessmentofTissueConstructsInVivoinRegenerativeEngineering427 AnuradhaSubramanianandSwaminathanSethuraman

BioengineeredKidneyandBladder432 DSKoslovandAAtala

BioengineeringScaffoldsforRegenerativeEngineering444 ZichenQian,DanielRadke,WenkaiJia,MitchTahtinen,GuifangWang,andFengZhao

BiomaterialsforTissueEngineeringandRegenerativeMedicine462 OhanSManoukian,NaseemSardashti,TeagenStedman,KatieGailiunas,AnuragOjha, AuraPenalosa,ChristopherMancuso,MichelleHobert,andSangameshGKumbar

BiomimeticApproachesforRegenerativeEngineering483 NirmalyaTripathy,RafiqAhmad,JeongEunSong,andGilsonKhang

Bioreactors:SystemDesignandApplicationforRegenerativeEngineering496 AntonioValdevit

BoneSubstituteMaterials 513 MBohner

CaseStudiesforSoftTissueRegenerativeEngineering530 JorgeLuisEscobarIviricoandCatoTLaurencin

CharacterizingthePropertiesofTissueConstructsforRegenerativeEngineering537 YusufKhan

ClinicalandLaboratoryAspectsofHematopoieticStemCellTransplantation546 STAvecillaandMMCushing

DentalStemCells 554 MNakashimaandYHayashi

DrugandGeneDeliveryforRegenerativeEngineering565 MorganAUrello,TianzhiLuo,BingFang,KristiLKiick,andMillicentOSullivan EthicsofIssuesandStemCellResearch:theUnresolvedIssues584 ZMaster

EyeDiseasesandStemCells 598 HOuyang,DHNguyen,andKZhang

HumanParthenogeneticPluripotentStemCells608

NTurovetsandMCsete

HumanPluripotentStemCells 618 PRajan

IntroductiontoRegenerativeEngineering624

ManishaJassal,RadoslawJunka,CatoTLaurencin,andXiaojunYu

NanoelectronicsforNeuroscience631

SahilKumarRastogiandTzahiCohen-Karni

NeuralCrestStemCells 650 THochgreb-HägeleandMEBronner

OsteoarthritisattheCellularLevel:Mechanisms,ClinicalPerspectives,andInsightsFromDevelopment660 MelanieFisher,TylerAckley,KelseyRichard,BridgetOei,andCarolineNDealy

ReproductiveTechnologies,Assisted677 DPergament

ToothRegenerativeTherapy:ToothTissueRepairandWholeToothReplacement686 MOshima,KIshida,RMorita,MSaito,andTTsuji

VascularizedTissueRegenerativeEngineeringUsing3DBioprintingTechnology696 SungwooKim,ArnaudBruyas,Chi-ChunPan,AlexanderMartinStahl,andYunzhiYang WoundHealingandtheHostResponseinRegenerativeEngineering707 DanielChester,EthanAMarrow,MichaelADaniele,andAshleyCBrown

CONTENTSOFALLVOLUMES

VOLUME1

Biomaterials:ScienceandEngineering

AlternativeProcessingTechniquesforCoCrDentalAlloys1 LucienReclaruandLaviniaCosminaArdelean

Bioceramics

BesimBen-Nissan,SophieCazalbou,andAndyHChoi

BiomedicalComposites

16

34 MinWangandQilongZhao

BulkPropertiesofBiomaterialsandTestingTechniques53 MinWangandChongWang

CorrosionofOrthopedicImplants65 QiongWang,FelipeEltit,andRizhiWang

DecellularizedExtracellularMatrix86 PaulFrankGratzer

Diamond,CarbonNanotubesandGrapheneforBiomedicalApplications97 AaqilRifai,ElenaPirogova,andKateFox

GoldNanoparticlesforColorimetricDetectionofPathogens108 PaulZChenandFrankXGu

ManufactureofBiomaterials

116 MinWang,LinGuo,andHaoranSun

MaterialsandTheirBiomedicalApplications135 MinWangandBinDuan

Nano-BiomaterialsandtheirApplications153 MianWangandThomasJWebster

NaturalBiopolymersforBiomedicalApplications162 NataliaDavidenko,RuthCameron,andSerenaBest

PolymericCoatingsandTheirFabricationforMedicalDevices177 DimitriosALamprou,NikolaosScoutaris,StevenARoss,andDionysiosDouroumis

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