Table of Contents
Instructions for online access
Cover image
Title Page Copyright
Dedication
Reviewers and Ancillary Contributors
LPN/LVN Advisory Board
Preface
Organization and Special Features
Special Features
New to This Edition
Teaching and Learning Package
For Instructors
Special Features
Study Guide
Unit I Applying Pharmacology to Nursing
Practice
1 Drug Definitions, Standards, and Information Sources
Drug Names, Standards, Legislation, and Development in the United States
Drug Names, Standards, and Legislation in Canada
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2 Basic Principles of Drug Action and Drug Interactions
Basic Principles Related to Drug Therapy
Drug Actions
Drug Interactions
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3 Drug Action Across the Life Span
Factors That Affect Drug Therapy
Factors That Influence Drug Actions
Therapeutic Drug Monitoring
Nursing Implications When Monitoring Drug Therapy
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4 The Nursing Process and Pharmacology
The Nursing Process
Relating the Nursing Process to Pharmacology
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5 Patient Education to Promote Health
Three Domains of Learning
Principles of Teaching and Learning
Strategies for Healthcare Teaching
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Administration
6 Principles of Medication Administration and Medication Safety
Legal and Ethical Considerations
Patient Charts
Drug Distribution Systems
Disposal of Unused Medicines
Medication Orders
Medication Safety
Seven Rights of Drug Administration
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7 Percutaneous Administration
Administration of Topical Medications to the Skin
Administration of Medications to Mucous Membranes
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8 Enteral Administration
Administration of Oral Medications
Administration of Solid-Form Oral Medications
Administration of Liquid-Form Oral Medications
Administration of Medications by Nasogastric, Nasoduodenal, Nasojejunal Tube
Administration of Enteral Feedings via Gastrostomy or Jejunostomy Tube
Administration of Rectal Suppositories
Administration of a Disposable Enema
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9 Parenteral Administration
Safe Preparation, Administration, and Disposal of Parenteral Medications and Supplies
Equipment Used for Parenteral Administration
Safety Systems for Parenteral Preparation, Administration, and Disposal
Parenteral Dose Forms
Preparation of Parenteral Medication
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10 Parenteral Administration
Administration of Medication by the Intradermal Route
Administration of Medication by the Subcutaneous Route
Administration of Medication by the Intramuscular Route
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11 Parenteral Administration
Equipment Used for Intravenous Therapy
Intravenous Dose Forms
Administration of Medications by the Intravenous Route
Basic Guidelines for the Intravenous Administration of Medications
Monitoring Intravenous Therapy
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Unit III Drugs Affecting the Autonomic and Central Nervous Systems
12 Drugs Affecting the Autonomic Nervous System
The Central and Autonomic Nervous Systems
The Autonomic Nervous System
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13 Drugs Used for Sleep
Sleep and Sleep Pattern Disturbance
Sedative-Hypnotic Therapy
Drug Therapy for Sleep Disturbance
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14 Drugs Used to Treat Neurodegenerative Disorders
Parkinson's Disease
Drug Therapy for Parkinson's Disease
Alzheimer's Disease
Drug Therapy for Alzheimer's Disease
15 Drugs Used for Anxiety Disorders
Anxiety Disorders
Drug Therapy for Anxiety Disorders
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16 Drugs Used for Depressive and Bipolar Disorders
Depressive and Bipolar Disorders
Depressive Disorder
Treatment of Depressive and Bipolar Disorders
Drug Therapy for Depressive and Bipolar Disorders
Drug Therapy for Depressive Disorders
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17 Drugs Used for Psychoses
Psychosis
Treatment of Psychosis
Drug Therapy for Psychosis
Adverse Effects of Antipsychotic Drug Therapy
Other Adverse Effects
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18 Drugs Used for Seizure Disorders
Seizure Disorders
Descriptions of Seizures
Antiepileptic Therapy
Drug Therapy for Seizure Disorders
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19 Drugs Used for Pain Management
Pain Pain Management Get Ready for the NCLEX® Examination!
20 Introduction to Cardiovascular Disease and Metabolic Syndrome
Cardiovascular Diseases
Metabolic Syndrome
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21 Drugs Used to Treat Dyslipidemias
Atherosclerotic Cardiovascular Disease
Treatment of Hyperlipidemias
Drug Therapy for Hyperlipidemias
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22 Drugs Used to Treat Hypertension
Hypertension
Treatment of Hypertension
Drug Therapy for Hypertension
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23 Drugs Used to Treat Dysrhythmias
Dysrhythmias
Treatment for Dysrhythmias
Drug Therapy for Dysrhythmias
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24 Drugs Used to Treat Angina Pectoris
Angina Pectoris
Treatment of Angina Pectoris
Drug Therapy for Angina Pectoris
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25 Drugs Used to Treat Peripheral Vascular Disease
Peripheral Vascular Disease
Treatment of Peripheral Vascular Disease
Drug Therapy for Peripheral Vascular Disease
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26 Drugs Used to Treat Thromboembolic Disorders
Thromboembolic Diseases
Treatment of Thromboembolic Diseases
Drug Therapy for Thromboembolic Diseases
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27 Drugs Used to Treat Heart Failure
Heart Failure
Treatment of Heart Failure
Drug Therapy for Heart Failure
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28 Drugs Used for Diuresis
Drug Therapy With Diuretics
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Unit V Drugs Affecting the Respiratory System
29 Drugs Used to Treat Upper Respiratory Disease
Upper Respiratory Tract Anatomy and Physiology
Common Upper Respiratory Diseases
Treatment of Upper Respiratory Diseases
Drug Therapy for Upper Respiratory Diseases
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30 Drugs Used to Treat Lower Respiratory Disease
Lower Respiratory Tract Anatomy and Physiology
Common Lower Respiratory Diseases
Treatment of Lower Respiratory Diseases
Drug Therapy for Lower Respiratory Diseases
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Unit VI Drugs Affecting the Digestive System
31 Drugs Used to Treat Oral Disorders
Oral Anatomy
Mouth Disorders
Drug Therapy for Mouth Disorders
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32 Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
Physiology of the Stomach
Common Stomach Disorders
Goals of Treatment
Drug Therapy
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33 Drugs Used to Treat Nausea and Vomiting
Nausea and Vomiting
Common Causes of Nausea and Vomiting
Drug Therapy for Selected Causes of Nausea and Vomiting
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34 Drugs Used to Treat Constipation and Diarrhea
Constipation
Diarrhea
Treatment of Altered Elimination
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Unit VII Drugs Affecting the Endocrine System
35 Drugs Used to Treat Diabetes Mellitus
Diabetes Mellitus
Complications of Diabetes Mellitus
Treatment of Diabetes Mellitus
Drug Therapy for Diabetes Mellitus
Incretin-Related Antidiabetic Therapy
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36 Drugs Used to Treat Thyroid Disease
Thyroid Gland
Thyroid Diseases
Treatment of Thyroid Diseases
Drug Therapy for Thyroid Diseases
Get Ready for the NCLEX® Examination! 37 Corticosteroids
Corticosteroids
Get Ready for the NCLEX® Examination! 38 Gonadal Hormones
The Gonads and Gonadal Hormones
Drug Therapy With Gonadal Hormones
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Unit VIII Drugs Affecting the Reproductive System
39 Drugs Used in Obstetrics
Obstetrics
Drug Therapy in Pregnancy
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40 Drugs Used in Men's and Women's Health
Vaginitis
Drug Therapy for Leukorrhea and Genital Infections
Drug Therapy for Contraception
Osteoporosis
Drug Therapy for Osteoporosis
Benign Prostatic Hyperplasia
Drug Therapy for Benign Prostatic Hyperplasia
Erectile Dysfunction
Drug Therapy for Erectile Dysfunction
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Unit IX Drugs Affecting Other Body Systems
41 Drugs Used to Treat Disorders of the Urinary System
Urinary Tract Infections
Drug Therapy for Urinary Tract Infections
Drug Therapy for Overactive Bladder Syndrome
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42 Drugs Used to Treat Glaucoma and Other Eye Disorders
Anatomy and Physiology of the Eye
General Considerations for Topical Ophthalmic Drug Therapy
Glaucoma
Drug Therapy for Glaucoma
Other Ophthalmic Agents
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43 Drugs Used to Treat Cancer
Cancer and the Use of Antineoplastic Agents
Drug Therapy for Cancer
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44 Drugs Used to Treat the Musculoskeletal System
Muscle Relaxants, Neuromuscular Blocking Agents, and Gout Agents
Drug Therapy for Musculoskeletal Disorders
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45 Drugs Used to Treat Infections
Antimicrobial Agents
Drug Therapy for Infectious Disease
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Unit X Drugs Affecting the General Health of the Body
Nutrition Principles of Nutrition Malnutrition Therapy for Malnutrition
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47 Herbal and Dietary Supplement Therapy
Herbal Medicines, Dietary Supplements, and Rational Therapy
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Classification of Substance Abuse
Substance Use Disorders
Signs of Impairment
Screening for Alcohol and Substance Abuse
Health Professionals and Substance Abuse
Principles of Treatment for Substance Abuse
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Appendixes
Appendix A Nomogram for Calculating the Body Surface Area of Adults, Children, and Infants
Appendix B Template for Developing a Written Record for Patients to Monitor Their Own Therapy
Bibliography
Index
The Joint Commission's Official “Do Not Use” List
Copyright
CLAYTON'S BASIC PHARMACOLOGY FOR NURSES, EIGHTEENTH
EDITION ISBN: 978-0-323-55061-1
Copyright © 2020 by Elsevier, Inc. All rights reserved.
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Notices
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility. With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to
verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.
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