Any screen. Any time. Anywhere.
Howard Fillit recognizes his mentors in geriatric medicine, particularly Robert Butler and Leslie Libow, for their inspiration and guidance. He is also grateful to Leonard and Ronald Lauder for their support and commitment to improving the quality of life for older people by conquering Alzheimer disease. He particularly wants to thank Aspasia Moundros for her constant, effective, and kind assistance in our work together.
Kenneth Rockwood is grateful to his many mentors in geriatric medicine: Duncan Robertson, John Brocklehurst, Peter McCracken, John Gray, Roy Fox, David Hogan, and Colin Powell, and to his colleagues, students, and patients who have taught him so much.
John Young has been privileged to work alongside inspiring clinicians: Graham Mulley and Alec Brownjohn (Leeds); and John Tucker, Maj Pushpangadan, and Alex Brown (Bradford). He thanks them all, and many others. And also his wife, Ghislaine, for her constant and kindhearted encouragement.
Nazanene Helen Esfandiari, MD
Clinical Assistant Professor Internal Medicine/Divsion of Metabolism, Endocrinology & Metabolism
University of Michigan Ann Arbor, Michigan
Julian Falutz, MD, FRCPC
Director Comprehensive HIV and Aging Initiative
Chronic Viral Illness Service; Senior Physician
Division of Geriatrics
Department of Medicine
McGill University Health Center Montreal, Quebec, Canada
Martin R. Farlow, MD Professor
Department of Neurology Indiana University Indianapolis, Indiana
Richard Feldstein, MD, MS
Clinical Assistant Professor Department of Internal Medicine
New York University School of Medicine
New York, New York
Howard M. Fillit, MD
Founding Executive Director and Chief Science Officer
Alzheimers Drug Discovery Foundation; Clinical Professor of Geriatric Medicine, Palliative Care and Neuroscience
Icahn School of Medicine at Mount Sinai New York, New York
Caleb E. Finch, PhD
ARCO-Kieschnick Professor of Gerontology
Davis School of Gerontology University of Southern California Los Angeles, California
Andrew Y. Finlay, CBE, FRCP Professor Department of Dermatology and Wound Healing
Division of Infection and Immunity
Cardiff University School of Medicine Cardiff, Wales, United Kingdom
James M. Fisher, MBBS, MRCP, MD Specialist Registrar in Geriatric and General Internal Medicine
Health Education North East Newcastle Upon Tyne, United Kingdom
Anne Forster, PhD, BA, FCSP Professor
Academic Unit of Elderly Care and Rehabilitation
University of Leeds and Bradford Teaching Hospitals NHS Foundation Trust Bradford, United Kingdom
Chris Fox, MBBS, BSc, MMedSci, MRCPsych, MD
Reader/Consultant Old Age Psychiatry
Norwich Medical School University of East Anglia Norwich, Norfolk, United Kingdom
Roger Michael Francis, MBChB, FRCP
Emeritus Professor of Geriatric Medicine
Institute of Cellular Medicine
Newcastle University
Newcastle upon Tyne, United Kingdom
Jasmine H. Francis, MD
Assistant Attending Ophthalmic Oncology Service Department of Surgery
Memorial Sloan Kettering Cancer Center
New York, New York
Terry Fulmer, PhD, RN, FAAN President
John A. Hartford Foundation
New York, New York
James E. Galvin, MD, MPH Professor
Department of Neurology, Psychiatry, Nursing, Nutrition and Popualtion Health
New York University Langone Medical Center
New York, New York
Maristela B. Garcia, MD
Division of Geriatrics Department of Medicine
David Geffen School of Medicine
University of California, Los Angeles
Los Angeles, California
Jim George, MBChB, MMEd, FRCP Consultant Physician
Department of Medicine for the Elderly Cumberland Infirmary Carlisle, United Kingdom
Neil D. Gillespie, BSc(Hons), MBChB, MD, FRCP(Ed), FHEA. Consultant Medicine for the Elderly
NHS Tayside
Dundee, United Kingdom
Robert Glickman, DMD
Professor and Chair
Oral and Maxillofacial Surgery
New York University College of Dentistry
New York, New York
Judah Goldstein, PCP, MSc, PhD Postdoctoral Fellow
Division of Emergency Medical Services
Dalhousie University
Halifax, Nova Scotia, Canada
Fernando Gomez, MD, MS
Geriatric Medicine Coordinator
Department of Geriatric Medicine
University of Caldas
Manizales, Caldas, Colombia
Leslie B. Gordon, MD, PhD
Medical Director
The Progeria Research Foundation
Peabody, Massachusetts; Associate Professor Department of Pediatrics
Alpert Medical School of Brown University and Hasbro Children’s Hospital
Providence, Rhode Island; Lecturer
Department of Anesthesia
Boston Children’s Hospital and Harvard University
Boston, Massachusetts
Adam L. Gordon, PhD, MBChB, MMedSci(Clin Ed)
Consultant and Honorary Associate Professor in Medicine of Older People
Department of Health Care of Older People
Nottingham University Hospitals NHS Trust
Nottingham, United Kingdom
Margot A. Gosney, MD, FRCP
Professor
Department of Clinical Health Sciences
University of Reading; Professor
Department of Elderly Care
Royal Berkshire NHS Foundation Trust Reading, United Kingdom
Leonard C. Gray, MBBS, MMed, PhD
Professor in Geriatric Medicine
School of Medicine
Director
Centre for Research in Geriatric Medicine; Director
Centre for Online Health
The University of Queensland Brisbane, Queensland, Australia
John Trevor Green, MB BCh, MD, FRCP, PGCME
Consultant Gastroenterologist/Clinical Senior Lecturer
Department of Gastroenterology
University Hospital Llandough Cardiff, Wales, United Kingdom
David A. Greenwald, MD Professor of Clinical Medicine
Albert Einstein College of Medicine; Associate Division Director
Department of Gastroenterology
Fellowship Program Director Division of Gastroenterology and Liver Diseases
Albert Einstein College of Medicine/ Montefiore Medical Center
Bronx, New York
Celia L. Gregson, BMedSci, BM, BS, MRCP, MSc, PhD
Consultant Senior Lecturer
Musculoskeletal Research Unit
University of Bristol Bristol, United Kingdom
Khalid Hamandi, MBBS MRCP, BSc
PhD
Consultant Neurologist
The Alan Richens Welsh Epilepsy Centre University Hospital of Wales Cardiff, Wales, United Kingdom
Yasir Hameed, MBChB, MRCPsych Honorary Lecturer
University of East Anglia, Specialist Registrar Norfolk and Suffolk NHS Foundation Trust
Norwich, Norfolk, United Kingdom; Clinical Instructor (St. George’s International School of Medicine True Blue, Grenada
Joanna L. Hampton, DME
Consultant
Addenbrookes Hospital
Cambridge University Hospitals Foundation Trust Cambridge, United Kingdom
Sae Hwang Han, MS
University of Massachusetts Boston Department of Gerontology Boston, Massachusetts
Steven M. Handler, MD, PhD Assistant Professor Division of Geriatric Medicine University of Pittsburgh Pittsburgh, Pennsylvania
Joseph T. Hanlon, PharmD, MS Professor Department of Geriatrics University of Pittsburgh, Schools of Medicine; Health Scientist Center for Health Equity Research and Geriatric Research Education and Clinical Center Veterans Affairs Pittsburgh Healthcare System Pittsburgh, Pennsylvania
Malene Hansen, PhD Associate Professor
Development, Aging and Regeneration Program
Sanford-Burnham Medical Research Institute
La Jolla, California
Vivak Hansrani, MBChB Clinical Research Fellow
Department of Academic Surgery Unit Institute of Cardiovascular Sciences Manchester, United Kingdom
Caroline Happold, MD Department of Neurology
University Hospital Zurich Zurich, Switzerland
Danielle Harari, MBBS, FRCP Consultant Physician in Geriatric Medicine
Department of Ageing and Health
Guy’s and St. Thomas’ NHS Foundation Trust; Senior Lecturer (Hon) Health and Social Care Research Kings College London London, United Kingdom
Carien G. Hartmans, MSc Researcher
Department of Psychiatry
VU University Medical Center
Amsterdam, the Netherlands; Clinical Neuropsychologist
Department of Psychiatry
Altrecht, Institute for Mental Health Care
Utrecht, the Netherlands
George A. Heckman, MD, MSc, FRCPC Schlegel Research Chair in Geriatric Medicine
Schlegel-University of Waterloo Research Institute for Aging School of Public Health and Health Systems
University of Waterloo Waterloo, Ontario, Canada
Vinod S. Hegade, MBBS, MRCP(UK), MRCP(Gastro)
Clinical Research Fellow Institute of Cellular Medicine; Honorary Hepatology Registrar Department of Hepatology Freeman Hospital, Newcastle upon Tyne, United Kingdom
Paul Hernandez, MDCM, FRCPC Professor of Medicine
Division of Respirology
Dalhousie University Faculty of Medicine; Respirologist Department of Medicine
QEII Health Sciences Centre Halifax, Nova Scotia, Canada
Paul Higgs, BSc, PhD
Professor of the Sociology of Ageing Department of Psychiatry University College London London, United Kingdom
Andrea Hilton, BPharm, MSc, PhD, MRPharmS, PGCHE, FHEA
Senior Lecturer
Faculty of Health and Social Care University of Hull Hull, United Kingdom
David B. Hogan, MD, FACP, FRCPC
Professor and Brenda Strafford
Foundation Chair in Geriatric Medicine
University of Calgary Calgary, Alberta, Canada
Søren Holm, BA, MA, MD, PhD, DrMedSci
Professor of Bioethics
School of Law
University of Manchester
Manchester, United Kingdom; Professor of Medical Ethics Centre for Medical Ethics, HELSAM
Oslo University
Oslo, Norway; Professor of Medical Ethics
Centre for Ethics in Practic Aalborg University
Aalborg, Denmark
Ben Hope-Gill, MBChB, MD, FRCP Consultant Respiratory Physician
Department Respiratory Medicine
Cardiff and Vale University Health Board
Cardiff, Wales, United Kingdom
Susan E. Howlett, BSc(Hons), MSc, PhD
Professor
Department of Pharmacology
Dalhousie University
Halifax, Nova Scotia, Canada; Professor Department of Cardiovascular Physiology
University of Manchester
Manchester, United Kingdom
Ruth E. Hubbard, BSc, MBBS, MRCP, MSc, MD, FRACP
Centre for Research in Geriatric Medicine
University of Queensland, Brisbane, Queensland, Australia
Joanna Hurley, MD, MBBCh, MRCP Consultant Gastroenterologist
Prince Charles Hospital
Merthyr Tydfil, United Kingdom
Steve Illiffe, BSc, MBBS, FRCGP, FRCP Professor
Department of Primary Care & Population Health
University College London London, United Kingdom
Carol Jagger, BSc, MSc, PhD
AXA Professor of Epidemiology of Ageing
Institute for Ageing and Health
Newcastle University
Newcastle upon Tyne, United Kingdom
C. Shanthi Johnson, PhD, RD
Professor
Faculty of Kinesiology and Health
Studies
University of Regina
Regina, Saskatchewan, Canada
Tomohiro Nakamura, PhD
Research Assistant Professor
Neuroscience and Aging Research Center Sanford-Burnham Medical Research Institute
La Jolla, California
Jennifer Greene Naples, PharmD, BCPS
Postdoctoral Fellow, Geriatric Pharmacotherapy Department Geriatrics University of Pittsburgh, Schools of Medicine and Pharmacy; Research Assistant Center for Health Equity Research and Geriatric Research Education and Clinical Center Veterans Affairs Pittsburgh Healthcare System Pittsburgh, Pennsylvania
James Nazroo, BSc(Hons), MBBS, MSc, PhD
Professor of Sociology Department of Sociology University of Manchester Manchester, United Kingdom
Michael W. Nicolle, MD, FRCPC, D.Phil. Chief, Division of Neurology Clinical Neurological Sciences University of Western Ontario London, Ontario, Canada
Alice Nieuwboer, MSc, PhD Neuromotor Rehabilitation Research Unit
Rehabilitation Sciences
Katholieke universiteit Leuven Leuven, Belgium
Kelechi C. Ogbonna, PharmD Assistant Professor, Geriatrics Department of Pharmacotherapy & Outcomes Science
Virginia Commonwealth University School of Pharmacy Richmond, Virginia
José M. Ordovás, PhD
Director Nutrition and Genomics
Professor Nutrition and Genetics Tufts University Boston, Massachussetts
Joseph G. Ouslander, MD
Professor and Senior Associate Dean for Geriatric Programs
Charles E. Schmidt College of Medicine, Chair
Integrated Medical Science Department
Charles E. Schmidt College of Medicine Florida Atlantic University
Boca Raton, Florida
Maria Papaleontiou, MD
Clinical Lecturer
Metabolism, Endocrinology and Diabetes University of Michigan
Ann Arbor, Michigan
Laurence D. Parnell, PhD
Computational Biologist
Nutrition and Genomics Laboratory
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University
Boston, Massachusetts
Judith Partridge, MSc MRCP
Proactive care of Older People undergoing Surgery (POPS) Department of Ageing and Health
Guy’s and St. Thomas’ NHS Foundation Trust
London, United Kingdom
Gopal A. Patel, MD, FAAD Dermatologist
Aesthetic Dermatology Associates
Riddle Memorial Hospital
Media, Pennsylvania
Steven R. Peacey, MBChB, MD, FRCP Department of Diabetes and Endocrinology
Bradford Teaching Hospitals NHS Foundation Trust
Bradford, United Kingdom
Kacper K. Pierwola, MD Department of Dermatology
Rutgers New Jersey Medical School
Newark, New Jersey
Megan Rose Perdue, MSW
Volunteer Adjunct Faculty
School of Social Work
San Jose State University
San Jose, California
Thomas T. Perls, MD, MPH
Professor Department Medicine
Boston University
Boston, Massachusetts
Emily P. Peron, PharmD, MS
Assistant Professor, Geriatrics
Department of Pharmacotherapy and Outcomes Science
Virginia Commonwealth University, Richmond, Virginia
Thanh G. Phan, PhD
Professor Department of Medicine
Monash University
Melbourne, Victoria, Australia; Professor
Department of Neurosciences
Monash Health
Clayton, Victoria, Australia
Katie Pink, MBBCh, MRCP
Department of Respiratory Medicine
University Hospital of Wales
Cardiff, Wales, United Kingdom
Joanna Pleming, MBBS, MSc
Specialist Registrar Department of Geriatric Medicine
Barnet Hospital
Hertfordshire, United Kingdom
John Potter, DM, FRCP
Professor
Department of Ageing and Stroke
Medicine
Norwich Medical School
University of East Anglia; Honorary Consultant Physician
Stroke and Older Persons Medicine
Norfolk and Norwich University Hospital, Norwich
Norwich, Norfolk, United Kingdom
Richard Pugh, BSc, MBChB, FRCA, FFICM, PGCM
Consultant in Anaesthetics and Intensive Care Medicine
Glan Clwyd Hospital
Bodelwyddan, Wales, United Kingdom; Honorary Clinical Lecturer
School of Medicine
Cardiff University
Cardiff, Wales, United Kingdom
Stephen Prescott, MD, FRCSEd(Urol)
Consultant Urological Surgeon
St. James’s University Hospital
Leeds Teaching Hospitals NHS Trust
Leeds, United Kingdom
Malcolm C.A. Puntis, PhD, FRCS
Senior Lecturer
Cardiff University; Consultant Surgeon
University Hospital of Wales
Cardiff, Wales, United Kingdom
David B. Reuben, MD
Archston Professor and Chief Division of Geriatrics Department of Medicine
David Geffen School of Medicine
Los Angeles, California
Kenneth Rockwood, MD, FRCPC, FRCP Professor of Geriatric Medicine & Neurology
Kathryn Allen Weldon Professor of Alzheimer Research
Department of Medicine
Dalhousie University, Consultant Physician
Department of Medicine
Nova Scotia Health Authority
Halifax, Nova Scotia, Canada; Honorary Professor of Geriatric Medicine
University of Manchester
Manchester, United Kingdom
Christopher A. Rodrigues, PhD, FRCP Consultant Gastroenterologist
Department of Gastroenterology
Kingston Hospital
Kingston-upon-Thames, Surrey, United Kingdom
Mohan K. Tummala, MD Mercy Hospital
Department of Oncology and Hematology Springfield, Missouri
Jane Turton, MBChB, MRCGP Associate Specialist Physician Department of Geriatric Medicine Cardiff and Vale University Health Board Cardiff, Wales, United Kingdom
Christine Van Broeckhoven, PhD, DSc Group Leader Neurodegenerative Brain Diseases
Department of Molecular Genetics VIB;
Research Director Laboratory of Neurogenetics Institute Born-Bunge; Professor University of Antwerp Antwerp, Belgium
Annick Van Gils, MSc, BSc Occupational therapist Stroke unit
University Hospitals Leuven Leuven, Belgium; Lecturer
Occupational Therapy Artevelde University College Ghent, Belgium
Jessie Van Swearingen, PhD, PT Associate Professor Department of Physical Therapy University of Pittsburgh Pittsburgh, Pennsylvania
Bruno Vellas, MD, PhD
Gérontopôle, Centre Hospitalier Universitaire de Toulouse INSERM UMR1027 Université de Toulouse III Paul Sabatier Toulouse, France
Emma C. Veysey, MBChB, MRCP Consultant Dermatologist St. Vincent’s Hospital Melbourne, Victoria, Australia
Geert Verheyden, PhD
Assistant Professor Department of Rehabilitation Sciences KU Leuven; Faculty Consultant
Department of Physical Medicine and Rehabilitation
University Hospitals Leuven Leuven, Belgium
Dennis T. Villareal, MD
Professor of Medicine Department of Medicine
Baylor College of Medicine; Staff Physician Department of Medicine
Michael E. DeBakey VA Medical Center Houston, Texas
Adrian S. Wagg, MB, FRCP, FRCP(E), FHEA
Professor of Healthy Aging Department of Medicine University of Alberta Edmonton, Alberta, Canada
Arnold Wald, MD Professor of Medicine Department of Medicine
Division of Gastroenterology & Hepatology
University of Wisconsin School of Medicine & Public Health Madison, Wisconsin
Rosalie Wang, BSc(Hon), BSc(OT), PhD
Assistant Professor
Department of Occupational Science and Occupational Therapy University of Toronto; Affiliate Scientist Department of Research—AI and Robotics in Rehabilitation Toronto Rehabilitation Institute— University Health Network Toronto, Ontario, Canada
Barbara Weinstein, MA, MPhi, PhD Professor and Founding Executive Officer AuD Program, Professor Department of Speech, Language, Hearing Sciences Graduate Center, CUNY New York, New York
Michael Weller, MD Professor and Chair Department of Neurology University Hospital Zurich Zurich, Switzerland
Sherry L. Willis, PhD
Research Professor of Psychiatry and Behavioral Sciences Department of Psychiatry and Behavioral Sciences
Co-director of the Seattle Longitudinal Study University of Washington Seattle, Washington
K. Jane Wilson, PhD, FRCP(Lond) Consultant Physician
Department of Medicine for the Elderly Addenbrooke’s Hospital
Cambridge University Hospitals NHS Trust
Cambridge, United Kingdom
Miles D. Witham, BM BCh, PhD
Clinical Senior Lecturer in Ageing and Health
Department of Ageing and Health
University of Dundee Dundee, United Kingdom
Henry J. Woodford, BSc, MBBS, FRCP Consultant Physician
Department of Elderly Medicine North Tyneside Hospital North Shields, Tyne and Wear, United Kingdom
Jean Woo, MA, MB BChir, MD Emeritus Professor of Medicine Medicine & Therapeutics
The Chinese University of Hong Kong Hong Kong, The People’s Republic of China
Frederick Wu, MD, FRCP(Lond), FRCP (Edin)
Professor of Medicine and Endocrinology Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical & Human Sciences
University of Manchester Manchester, United Kingdom
John Young, MBBS(Hons) FRCP
Professor of Elderly Care Medicine
Academic Unit of Elderly Care and Rehabilitation
University of Leeds, United Kingdom; Honorary Consultant Geriatrician Bradford Teaching Hospitals NHS Foundation Trust Bradford, United Kingdom
Zahra Ziaie, BS Laboratory Manager
Science Center Port at University City Science Center Philadelphia, Pennsylvania
71 Orthopedic Geriatrics, 573
Robert V. Cantu
72 Sarcopenia, 578
Yves Rolland, Matteo Cesari, Bruno Vellas
SECTION F Gastroenterology, 585
73 The Pancreas, 585
J.C. Tham, Ceri Beaton, Malcolm C.A. Puntis
74 The Liver, 596
Arjun Sugumaran, Joanna Hurley, John Trevor Green
75 Biliary Tract Diseases, 606
Noor Mohammed, Vinod S. Hegade, Sulleman Moreea
76 The Upper Gastrointestinal Tract, 616
David A. Greenwald, Lawrence J. Brandt
77 The Small Bowel, 633
Saqib S. Ansari, Sulleman Moreea, Christopher A. Rodrigues
78 The Large Bowel, 643
Arnold Wald
79 Nutrition and Aging, 660 C. Shanthi Johnson, Gordon Sacks
80 Obesity, 667
Krupa Shah, Dennis T. Villareal
SECTION G Genitourinary Tract, 672
81 Diseases of the Aging Kidney, 672
John M. Starr, Latana A. Munang
82 Disorders of Water and Electrolyte Metabolism, 681
Amanda Miller, Karthik Tennankore, Kenneth Rockwood
83 The Prostate, 689
William Cross, Stephen Prescott
84 Aging Males and Testosterone, 702
Frederick Wu, Tomas Ahern
SECTION H Women’s Health, 708
85 Gynecologic Disorders in Older Women, 708
Tara K. Cooper, Oliver Milling Smith
86 Breast Cancer, 717
Lodovico Balducci, Dawn Dolan, Christina Laronga
SECTION I Endocrinology, 724
87 Adrenal and Pituitary Disorders, 724
Steven R. Peacey
88 Disorders of the Thyroid, 731
Maria Papaleontiou, Nazanene Helen Esfandiari
89 Disorders of the Parathyroid Glands, 742
Jane Turton, Michael Stone, Duncan Cole
90 Diabetes Mellitus, 747
Alan J. Sinclair, Ahmed H. Abdelhafiz, John E. Morley
SECTION J Hematology and Oncology, 757
91 Blood Disorders in Older Adults, 757
William B. Ershler
92 Geriatric Oncology, 772
Margot A. Gosney
93 Clinical Immunology: Immune Senescence and the Acquired Immunodeficiency of Aging, 781
Mohan K. Tummala, Dennis D. Taub, William B. Ershler
SECTION K Skin and Special Senses, 789
94 Skin Disease and Old Age, 789
Kacper K. Pierwola, Gopal A. Patel, W. Clark Lambert, Robert A. Schwartz
95 Aging and Disorders of the Eye, 799
Scott E. Brodie, Jasmine H. Francis
96 Disorders of Hearing, 811
Barbara Weinstein
PART III
Problem-Based Geriatric Medicine
SECTION A Prevention and Health Promotion, 819
97 Health Promotion for Community-Living Older Adults, 819
Maureen F. Markle-Reid, Heather H. Keller, Gina Browne
98 Sexuality in Old Age, 831
Carien G. Hartmans
99 Physical Activity for Successful Aging, 836
Olga Theou, Debra J. Rose
100 Rehabilitation: Evidence-Based Physical and Occupational Therapy Techniques for Stroke and Parkinson Disease, 843
Geert Verheyden, Annick Van Gils, Alice Nieuwboer
SECTION B Geriatric Syndromes and Other Unique Problems of the Geriatric Patient, 849
101 Geriatric Pharmacotherapy and Polypharmacy, 849
Jennifer Greene Naples, Steven M. Handler, Robert L. Maher, Jr., Kenneth E. Schmader, Joseph T. Hanlon
102 Impaired Mobility, 855
Nancy L. Low Choy, Eamonn Eeles, Ruth E. Hubbard
103 Falls, 864
Stephanie Studenski, Jessie Van Swearingen
104 Podiatry, 873
Hylton B. Menz
105 Constipation and Fecal Incontinence in Old Age, 877
Danielle Harari
106 Urinary Incontinence, 895
Adrian S. Wagg
107 Pressure Ulcers, 904
Bryan D. Struck
108 Sleep in Relation to Aging, Frailty, and Cognition, 908
Roxanne Sterniczuk, Benjamin Rusak
