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Publisher Cataloging-in-Publication Data
Names: Nielsen, G. Petur (Gunnlaugur Petur) | Rosenberg, Andrew, 1953-
Title: Diagnostic pathology. Bone / [edited by] G. Petur Nielsen and Andrew E. Rosenberg. Other titles: Bone.
Description: Second edition. | Salt Lake City, UT : Elsevier, Inc., [2017] | Includes bibliographical references and index.
Identifiers: ISBN 978-0-323-47777-2
Subjects: LCSH: Bones--Tumors--Handbooks, manuals, etc. | MESH: Bone Neoplasms--pathology--Atlases. | Bone Neoplasms--diagnosis--Atlases.
International Standard Book Number: 978-0-323-47777-2
Cover Designer: Tom M. Olson, BA
Printed in Canada by Friesens, Altona, Manitoba, Canada
Last digit is the print number: 9 8 7 6 5 4 3 2 1
Preface
The pathology of the skeleton is complex and is the morphologic expression of a broad spectrum of diseases, including those caused by genetic (sporadic and inherited), malformative, inflammatory, metabolic, circulatory, traumatic, iatrogenic, and neoplastic disorders. Bone tumors, including both neoplasms and various conditions that may simulate them, are the focus of our book. This topic is one of the most challenging areas in surgical pathology for several reasons: Bone tumors are uncommon, making it difficult to acquire the necessary experience with their histological variants and mimics; the correct diagnosis usually requires the careful integration of radiological imaging studies and clinical findings; the implications of a diagnosis on a patient can be life changing; and medical schools and pathology training programs often have insufficient expertise to provide medical students and young pathologists with the skills needed to diagnose these lesions accurately and precisely.
This book reflects the philosophy and high standards practiced by the truly multidisciplinary team of physicians at the Massachusetts General Hospital and University of Miami, who have diagnosed and surgically treated tens of thousands of patients with bone tumors for many decades. Also important to acknowledge are the contributions of the many fellows and residents who participated in the efforts of patient care.
The authors are subspecialized physicians who have dedicated their professional lives to the diagnosis and surgical management of bone tumors. As a result, the figures include beautiful and classic examples and unusual variants of many of the diseases discussed and are the product of painstaking correlations between the clinical, imaging, macroscopic, histological, immunohistochemical, and molecular characteristics of bone tumors. The text synthesizes the literature and our combined extensive experience, and the images have been selectively culled from the patient files of the Massachusetts General Hospital, the University of Miami Miller School of Medicine, and the private consultations of the authors. The book is constructed in a thematic format with sections representing groups of related diseases and the chapters discussing individual entities and their differential diagnosis.
Accordingly, this textbook serves as an excellent resource for medical students, residents, fellows, and practicing physicians in the disciplines of pathology, radiology, and orthopedics. Medical and radiation oncologists who treat bone tumors will also find it valuable. Our opportunity to participate in the care of patients with bone tumors has been our call and honor, and we hope to do it justice by sharing our experience with the medical community—our goal is to enhance diagnostic accuracy and to provide the biological basis for optimal treatment.
