A systematic literature review of blockchain-based applications_ current status, classification and

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A systematic literature review of blockchainbased applications_ Current status, classification and open issues Fran Casino & Thomas K. Dasaklis & Constantinos Patsakis

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TelematicsandInformatics36(2019)55–81

TelematicsandInformatics

journalhomepage: www.elsevier.com/locate/tele

Asystematicliteraturereviewofblockchain-basedapplications:

Currentstatus,classificationandopenissues

FranCasinoa,ThomasK.Dasaklisb,ConstantinosPatsakisa,⁎

a DepartmentofInformatics,UniversityofPiraeus,80Karaoli&Dimitrioustr.,18534Piraeus,Greece

b DepartmentofIndustrialManagementandTechnology,UniversityofPiraeus,80Karaoli&Dimitrioustr.,18534Piraeus,Greece

ARTICLEINFO

Keywords: Blockchain Classification Applications

ABSTRACT

Thisworkprovidesasystematicliteraturereviewofblockchain-basedapplicationsacrossmultipledomains.Theaimistoinvestigatethecurrentstateofblockchaintechnologyanditsapplicationsandtohighlighthowspecificcharacteristicsofthisdisruptivetechnologycanrevolutionise“business-as-usual”practices.Tothisend,thetheoreticalunderpinningsofnumerous researchpaperspublishedinhighrankedscientificjournalsduringthelastdecade,alongwith severalreportsfromgreyliteratureasameansofstreamliningourassessmentandcapturingthe continuouslyexpandingblockchaindomain,areincludedinthisreview.Basedonastructured, systematicreviewandthematiccontentanalysisofthediscoveredliterature,wepresenta comprehensiveclassificationofblockchain-enabledapplicationsacrossdiversesectorssuchas supplychain,business,healthcare,IoT,privacy,anddatamanagement,andweestablishkey themes,trendsandemergingareasforresearch.Wealsopointtotheshortcomingsidentifiedin therelevantliterature,particularlylimitationstheblockchaintechnologypresentsandhowthese limitationsspawnacrossdifferentsectorsandindustries.Buildingonthesefindings,weidentify variousresearchgapsandfutureexploratorydirectionsthatareanticipatedtobeofsignificant valuebothforacademicsandpractitioners.

1.Introduction

AlmostadecadeagoSatoshiNakamoto,theunknownperson/groupbehindBitcoin,describedhowtheblockchaintechnology,a distributedpeer-to-peerlinked-structure,couldbeusedtosolvetheproblemofmaintainingtheorderoftransactionsandtoavoidthe double-spendingproblem(Nakamoto,2008).Bitcoinorderstransactionsandgroupstheminaconstrained-sizestructurenamed blocks sharingthesametimestamp.Thenodesofthenetwork(miners)areresponsibleforlinkingtheblockstoeachotherin chronologicalorder,witheveryblockcontainingthehashofthepreviousblocktocreateablockchain(Crosbyetal.,2016).Thus,the blockchainstructuremanagestocontainarobustandauditableregistryofalltransactions.

Blockchainsintroducedseriousdisruptionstothetraditionalbusinessprocessessincetheapplicationsandtransactions,which neededcentralisedarchitecturesortrustedthirdpartiestoverifythem,cannowoperateinadecentralisedwaywiththesamelevelof certainty.Theinherentcharacteristicsofblockchainarchitectureanddesignprovidepropertiesliketransparency,robustness,auditability,andsecurity(Greenspan,2015a;ChristidisandDevetsikiotis,2016).Ablockchaincanbeconsideredadistributeddatabase thatisorganisedasalistoforderedblocks,wherethecommittedblocksareimmutable.Onecanseethatthisisidealinthebanking sectorasbankscancooperateunderthesameblockchainandpushtheircustomers’transactions.Thisway,beyondtransparency, https://doi.org/10.1016/j.tele.2018.11.006

⁎ Correspondingauthor.

E-mailaddresses: francasino@unipi.gr (F.Casino), dasaklis@unipi.gr (T.K.Dasaklis), kpatsak@unipi.gr (C.Patsakis).

Received30May2018;Receivedinrevisedform16November2018;Accepted17November2018

Availableonline22November2018

0736-5853/©2018TheAuthors.PublishedbyElsevierLtd.ThisisanopenaccessarticleundertheCCBY-NC-NDlicense (http://creativecommons.org/licenses/BY-NC-ND/4.0/).

blockchainfacilitatestransactions’auditing.Companiesinvestinthistechnologyastheyseethepotentialofmakingtheirarchitecturesdecentralisedandminimisingtheirtransactioncostsastheybecomeinherentlysafer,transparentandinsomecasesfaster. Therefore,blockchainsarenotjustahype.

ThenumberofcryptocurrenciesillustratesBlockchain’simportance,currentlyexceeding1900andgrowing(CoinMarketCap, 2017).Suchagrowthpacecouldsooncreateinteroperabilityproblemsduetotheheterogeneityofcryptocurrencyapplications (TschorschandScheuermann,2016;HaferkornandQuintanaDiaz,2015).Furthermore,thelandscapeisrapidlyevolvingas blockchainisbeingusedinotherfieldsbeyondcryptocurrencies,with SmartContracts(SCs) playingacentralrole.SCsdefinedin 1994bySzaboas: “acomputerisedtransactionprotocolthatexecutesthetermsofacontract” (Szabo,1994),allowustotranslate contractualclausesintoembeddablecode(Szabo,1997)thusminimizingexternalparticipationandrisks.So,aSCisanagreement betweenpartieswhich,althoughtheydonottrusteachother,theagreedtermsareautomaticallyenforced.Therefore,withinthe blockchaincontext,SCsarescriptsrunninginadecentralisedmannerandstoredintheblockchain(ChristidisandDevetsikiotis, 2016)withoutrelyingonanytrustedauthority.Inparticular,blockchain-basedsystemssupportingSCsenablemorecomplexprocessesandinteractionssotheyestablishanewparadigmwithpracticallylimitlessapplications.

Asaresult,Blockchaintechnologyisbecomingincreasinglyrelevant(Zhaoetal.,2016).Almost1000(33%)ofC-suiteexecutives declarethattheyareconsideringorhavealreadybeenactivelyengagedwithblockchains(IBM,2017).Researchersanddevelopers arealreadyawareofthecapabilitiesofthenewtechnologyandexplorevariousapplicationsacrossavastarrayofsectors(Christidis andDevetsikiotis,2016).Basedontheintendedaudience,threegenerationsofblockchainscanbedistinguished(Zhaoetal.,2016): Blockchain1.0whichincludesapplicationsenablingdigitalcryptocurrencytransactions;Blockchain2.0whichincludesSCsandaset ofapplicationsextendingbeyondcryptocurrencytransactions;andBlockchain3.0whichincludesapplicationsinareasbeyondthe previoustwoversions,suchasgovernment,health,scienceandIoT.

Whilethereareseveralreviewsregardingblockchaintechnology(Tamaetal.,2017;Brandãoetal.,2018),wearguethatthe state-of-the-artofblockchain-enabledapplicationshasreceivedlimitedattention.Evenin Zhengetal.(2016) theapplicationsof blockchainsarenotcoveredtotheirfullextentnorapplicability.Thereareindeedsomereviewsfocusedontheparticularroleof blockchainincludingthedevelopmentofdecentralisedanddata-intensiveapplicationsfortheIoT(Conoscentietal.,2016;Christidis andDevetsikiotis,2016),andmanagingbigdatainadecentralisedfashion(KarafiloskiandMishev,2017a).Otherreviewsfocuson securityissuesoftheblockchain(KhanandSalah,2017;Lietal.,2017a;Mengetal.,2018)andonitspotentialtoenabletrustand decentralisationinservicesystems(Seebacheretal.,2017)andP2Pplatforms(Hawlitscheketal.,2018).Sometechnicalaspectsof theblockchaindesignsuchasitsconsensusprotocol(Sankaretal.,2017),thevulnerabilitiesofSCs(Atzeietal.,2017)andother technicalcharacteristicslikeitssizeandbandwidth,usability,dataintegrity,andscalabilityhavealsobeenstudiedin Yli-Huumo etal.(2016)andKoteskaetal.(2017).Moreover,thereareothersurveyssuchas Bonneauetal.(2015),Tsukerman(2015), Mukhopadhyayetal.(2016),KhalilovandLevi(2018)andContietal.(2018) whicharemorefocusedonthecurrencyaspectof blockchainsandtheofferedsecurityandprivacy.

Evidently,theliteraturelacksaconcreteandsystematicreviewofthecurrentblockchain-enabledstate-of-the-artapplications,a limitationwhichwastheprimarydriverforconductingthisresearch.Inparticular,wetrytoaddressthisbyansweringthefollowing threequestions:(i)Howblockchain-basedapplicationsdevelopovertime?(ii)Howcertaintechnicallimitationsoftheblockchain architectureaffectprocedures/processesinparticulardomains?Whicharetheselimitations?(iii)Whatisthesuitabilityofblockchain technologyacrossdifferentdomainsandthematicareas?

Ourworkcontributestowardsathoroughunderstandingoftheblockchainfeaturesandprovidesasnapshotofcurrentblockchain-enabledapplicationsacrosssectors.Basedonacontentanalysisapproach,wehighlightthegrowinginterestfromtheacademic communityandidentifythreekeyresearchstreams:(i)classificationoftherangeofblockchain-basedapplicationsacrossavastarray ofsectors(ii)suitabilityoftheblockchaintechnologytocreatevalueinthesesectorstakingintoaccountthevariouslimitationsthis technologypresents,and(iii)guidingresearchersbyprovidingaroadmapofpromisingresearchavenues,challengesandopportunitiesforwhichfurtherresearchisneeded.Itisworthnotingthatthisreviewcannotbyanymeansbeconsideredasexhaustive sinceblockchaintechnologyiscontinuouslygrowingataveryfastpace.

Theremainderofthisworkisorganizedasfollows.InSection 2 abriefoverviewofblockchainarchitectureispresented.The methodfollowedtoconductthesystematicliteraturereviewisoutlinedinSection 3.Thedescriptiveanalysisoftheretrieved literatureispresentedinSection 4 whileinSection 5 ataxonomyoftheblockchain-basedapplicationsispresented.Relevantopen issues,trends,andfurtherresearchlinesarediscussedinSection 6.

2.Blockchainoverview

Inprinciple,ablockchainshouldbeconsideredasa distributedappend-onlytimestampeddatastructure.Blockchainsallowusto haveadistributedpeer-to-peernetworkwherenon-trustingmemberscanverifiablyinteractwitheachwithouttheneedforatrusted authority(ChristidisandDevetsikiotis,2016).Toachievethisonecanconsiderblockchainasasetofinterconnectedmechanisms whichprovidespecificfeaturestotheinfrastructure,asillustratedin Fig.1.Atthelowestlevelofthisinfrastructure,wehavethe signed transactions betweenpeers.Thesetransactionsdenoteanagreementbetweentwoparticipants,whichmayinvolvethetransfer ofphysicalordigitalassets,thecompletionofatask,etc.Atleastoneparticipantsignsthistransaction,anditisdisseminatedtoits neighbours.Typically,anyentitywhichconnectstotheblockchainiscalleda node.However,nodesthatverifyalltheblockchain rulesarecalled fullnodes.Thesenodesgroupthetransactionsinto blocks andtheyareresponsibletodeterminewhetherthe transactionsarevalid,andshouldbekeptintheblockchain,andwhicharenot.

Avalidtransactionmeans,forinstance,thatBobreceivedonebitcoinfromAlice.However,Alicemayhavetriedtotransferthe

samebitcoin,asitisadigitalasset,toCarol.Therefore,nodesmustreachtoanagreementonwhichtransactionsmustbekeptinthe blockchaintoguaranteethattherewillbenocorruptbranchesanddivergences(Vukolić,2015;ChristidisandDevetsikiotis,2016). Thisisactuallythegoalofthesecond Consensus layer.Dependingontheblockchaintype,differentConsensusmechanismsexist (Mingxiaoetal.,2017).Themostwell-knownisthe Proof-of-work(PoW).PoWrequiressolvingacomplicatedcomputationalprocess, likefindinghasheswithspecificpatterns,e.g.aleadingnumberofzeroes(Antonopoulos,2014),toensureauthenticationand verifiability.Insteadofsplittingblocksacrossproportionallytotherelativehashratesofminers(i.e.,theirminingpower), Proof-ofStake(PoS) protocolssplitstakeblocksproportionallytothecurrentwealthofminers(Pilkington,2016).Thisway,theselectionis fairerandpreventsthewealthiestparticipantfromdominatingthenetwork.Manyblockchains,suchasEthereum(Dannen,2017), aregraduallyshiftingtoPoSduetothesignificantdecreaseinpowerconsumptionandimprovedscalability.Otherconsensusapproachesinclude ByzantineFaultTolerance(BFT) (CastroandLiskov,2002)anditsvariants(Zhengetal.,2016).

Anadditionallayer,the ComputeInterface,allowsblockchainstooffermorefunctionality.Practically,ablockchainstoresastate whichconsistse.g.ofallthetransactionsthathavebeenmadebytheusers,therebyallowingthecalculationofeachuser’sbalance. However,formoreadvancedapplicationsweneedtostorecomplexstateswhichareupdateddynamicallyusingdistributedcomputing,e.g.statesthatshiftfromonetoanotheroncespecificcriteriaaremet.ThisrequirementhasgivenrisetoSCswhichusenodes oftheblockchaintoexecutethetermsofacontract.

Finally,the Governance layerextendstheblockchainarchitecturetocoverthehumaninteractionstakingplaceinthephysical world.Indeed,althoughblockchainsprotocolsarewelldefined,theyarealsoaffectedbyinputsfromdiversegroupsofpeoplewho integratenewmethods,improvetheblockchainprotocolsandpatchthesystem.Whilethesepartsarenecessaryforthegrowthof eachblockchain,theyconstituteoff-chainsocialprocesses.Therefore,blockchaingovernancedealswithhowthesediverseactors cometogethertoproduce,maintain,orchangetheinputsthatmakeupablockchain.1

Currentliteraturecategorisesblockchainnetworksinseveralways(Buterin,2015;Zhengetal.,2016;ErisIndustries,2016; ChristidisandDevetsikiotis,2016;Kravchenko,2016;Wood,2016).Thesecategoriesareformedaccordingtothenetwork’smanagementandpermissionsas public, private and federated.Inpublicblockchains(permissionless)anyonecanjoinasanewuserornode miner.Moreover,allparticipantscanperformoperationssuchastransactionsorcontracts.Inprivateblockchains;whichalongwith thefederatedbelongtothe permissioned blockchaincategory,usually,awhitelistofallowedusersisdefinedwithparticularcharacteristicsandpermissionsoverthenetworkoperations.SincetheriskofSybilattacksisalmostnegligiblethere(Swanson,2015), privateblockchainnetworkscanavoidexpensivePoWmechanisms.Instead,awiderrangeofconsensusprotocolsbasedondisincentivescouldbeadopted.Afederatedblockchainisahybridcombinationofpublicandprivateblockchains(Buterin,2015;Zheng etal.,2016).Althoughitsharessimilarscalabilityandprivacyprotectionlevelwithprivateblockchain,theirmaindifferenceisthata setofnodes,named leader nodes,isselectedinsteadofasingleentitytoverifythetransactionprocesses.Thisenablesapartially decentraliseddesignwhereleadernodescangrantpermissionstootherusers.Inthisarticle,weprovideamorefine-grained blockchainnetworkclassificationthancurrentthestate-of-the-art(Buterin,2015;Zhengetal.,2016;ChristidisandDevetsikiotis, 2016;Kravchenko,2016)because,inadditiontoclassicalfeaturessuchastheownershipandmanagementoftheinformationshared intheblockchain,weconsiderfeaturessuchastransactionapprovaltime,orsecurityaspectssuchasanonymity. Table1 summarises themaincharacteristicsofeachblockchainnetworkregardingefficiency,securityandconsensusmechanisms.

Well-knownimplementationsofpublicblockchainsincludeBitcoin,Ethereum,Litecoinand,ingeneral,mostcryptocurrencies (Nakamoto,2008;HaferkornandQuintanaDiaz,2015).Oneoftheirmainadvantagesisthelackofinfrastructurecosts:thenetwork isself-sustainedandcapableofmaintainingitself,drasticallyreducingmanagementoverheads.Inprivateblockchains,themain applicationsaredatabasemanagement,auditingand,ingeneral,performancedemandingsolutions(Zhengetal.,2016).Multichain (Greenspan,2015b)isanexampleofanopenplatformforbuildinganddeployingprivateblockchains.Finally,federatedblockchains aremostlyusedinthebankingandindustrysectors(R3,2015).ThisisthecaseoftheHyperledgerproject(HyperledgerProject, 2015)whichdevelopscross-industrypermission-basedblockchainframeworks.Recently,Ethereumhasalsoprovidedtoolsfor buildingfederatedblockchains.Otherprojectssuchas Cardano(2018) areratherambitioustryingtoprovidemorefunctionality.For moreonblockchaincategorisation,theinterestedreadermayreferto Walport(2016)andSwanson(2015)

1 https://www.oii.ox.ac.uk/blog/understanding-public-blockchain-governance/.

Fig.1. Anoverviewofblockchainarchitecture.

Table1

Classificationandmaincharacteristicsofblockchainnetworks.

Property Public Private Federated

Consensus

Mechanism

Identity

Anonymity

ProtocolEfficiency&

Consumption

Immutability

Ownership&

•CostlyPoW

•Allminers

•(Pseudo)Anonymous

•Malicious?

•Lowefficiency

•Highenergy

•Almostimpossible

•Public

•LightPoW

•Centralisedorganisation

•Identifiedusers

•Trusted

•Highefficiency

•Lowenergy

•Collusionattacks

•Centralised

•LightPoW

•Leadernodeset

•Identifiedusers

•Trusted

•Highefficiency

•Lowenergy

•Collusionattacks

•Semi-Centralised Management

TransactionApproval

3.Researchmethodology

•Permissionless

•Orderofminutes

•Permissionedwhitelist

•Orderofmilliseconds

•Permissionednodes

•Orderofmilliseconds

Toprovideatransparent,reproducibleandscientificliteraturereviewofblockchain-basedapplications,theprocesssuggestedby BrinerandDenyer(2012) aswellassomefeaturesofthePRISMAstatement(Moheretal.,2009)havebeenadopted.Theoverall methodologicalapproachincludesthefollowingsteps:

1.Identifytheneedforthereview,prepareaproposalforthereview,anddevelopthereviewprotocol.

2.Identifytheresearch,selectthestudies,assessthequality,takenotesandextractdata,synthesisethedata.

3.Reporttheresultsofthereview.

3.1.Locatingstudies

Toaddressourprimaryresearchquestion,asystematicliteraturesearchwascarriedoutduringJanuary2018withouttimeframe restrictionsandtheresultsweresubsequentlyupdatedduringApril2018.Scopuswasusedasthemainscientificdatabaseinwhich theterm“blockchain”wassearchedinallarticles’titles.Additionalsearchesusingthereferencedworksofrelevantarticleswerealso conducted(snowballeffect).Relevant“greyliterature”,includingunpublishedresearchcommissionedbygovernmentsorprivate/ publicinstitutionswasalsoidentifiedthroughelectronicsearches.Toidentifythepublishedgreyliterature,weevaluatedthefirst 200hitsfromGoogle.Alternatetermsfor“blockchain”and“application”wereusedduringthesearch.Thehand-searchreferencelist inseveralreportsresultedinadditionalgreyliterature,particularlyresearchandcommitteereportsorpolicybriefsfrombothprivate andpublicsectorinstitutions/organizations.Aflowchartofthestrategyimplementedispresentedin Fig.2.Inaddition,several refinementfeaturesofScopuswereextensivelyused(multiplerefinementsofresultsfollowingthecontextofspecificarticles,related documentssearch,etc.).Whentheabstractofaparticularstudywasnotavailable,thefullarticlewasretrievedandassessedfor relevance.Allpotentiallyrelevantarticleswereretrievedinfulltext.

3.2.Studyselectionandevaluation

Theeligibilityoftheretrievedliteraturewasevaluatedindependentlybytheauthorsbasedonasetofpredefinedexclusionand inclusioncriteria(see Table2).Someexclusioncriteriawereusedbeforeintroducingtheliteratureinthebibliographicmanager (language,subjectareaanddocumenttyperestrictions).Initially,theabstractsofallresearchpapersandintroductorysectionsof greyliteraturewereassessed.Articlesmeetingoneoftheexclusioncriteriawereexcludedandsortedbyreasonofexclusion. Afterwards,afull-textreviewalsotookplace,andsomeadditionalarticleswereexcludedfromthestudydocumentingthereasonsfor exclusion.Anydiscrepancywithrespecttotherelevanceofreviewedarticleswasresolvedthroughdiscussionuntilconsensuswas reached.Overall,severalstudieswereexcludedbecausetheywerefocusedprimarilyonthetechnicalaspectsofblockchaintechnologyand/orblockchainarchitecture.Articlesnotfittingtheinclusioncriteriaweresetasideandconsequentlyusedintheintroductionofthisarticle.

3.3.Analysisandsynthesis

Allarticlesandreportsmeetingtheinclusioncriteriawereenteredintoaqualitativeanalysissoftware(MAXQDA11),anddata wereanalysedinemergingthemes.Thereviewersindependentlycarriedoutthethematiccontentanalysis.Afterwards,thethree clustersofcodedsegmentswerecompared(rateofconsensuswasapproximately75%),agreeduponforallarticlesandsummarised inonesetofthemesandsub-themes.

Table2

Inclusionandexclusioncriteria.

Selectioncriteria

Scientificdatabase

Inclusion Peer-reviewedresearcharticles(includingarticlesinpress),conferenceproceedings papers,bookchapters,reviewpapers,shortsurveys,serialsetc.

Withouttime-framerestrictions

ExclusionPriortoimportationto bibliographicmanager

Duringtitlescreening

NonEnglisharticles,articleswithmissing abstracts,notes,editorials

Genericarticlesrelatedtotheblockchain technologyand/orblockchainarchitecture

Duringabstractscreening Software-orientedarticlesrelatedtothe blockchaintechnology

Duringfull-textscreening Articlesaddressingtechnicalaspectsof blockchaintechnology

4.Descriptiveanalysis

Greyliterature

Englishreports

Withouttime-framerestrictions

Genericreportsrelatedtotheblockchain technologywithoutdescribingspecific applications.

Thestudyanalyzes260researchpaperspublishedbetween2014andApril2018(forconformity,greyliteraturehasbeenexcludedfromthedescriptiveanalysis).Thepurposeofthedescriptiveanalysisisthreefold:(i)itprovidesinterestinginsightsregarding currentresearchtrendsinblockchaintechnology,anditsapplications(ii)ithelpstovisualisethemultidisciplinaryresearchapproachesdevelopedsofarinthescientificliterature,and(iii)itfurthersupportstheclassificationstructurepresentedinSection 5 Forclassifyingtheavailableliterature,thedescriptiveanalysisisbasedontwokey-criteria:(i)distributionofpublicationsovertime andthematicareaand(ii)distributionoftypeofpublicationovertime.

Ayear-wiseanalysisoftheselectedpapersisillustratedin Fig.3.Itisworthnotingthatduring2017thenumberofpublications hassky-rocketed.Until2016justalittlemoreof40publicationsexistedrelatedtoblockchain-enabledapplicationswhereasduring 2017theirnumberreachedalmost180.Therefore,researchhasslowly,yetsignificantly,pickedupintheareaofblockchain-enabled applicationsduringthelastcoupleofyears.Thisupwardtrendhighlightstheemergingandgrowingnatureoftheblockchain technologyandthegrowingacademicinterest.EventhoughblockchaintechnologywasfirstintroducedwithBitcoinasitscore underlyingtechnology,ittookseveralyearstotheresearchcommunitytobecomefullyawareofblockchain’spotentialandtotake advantageofitspossibleapplications.Unsurprisingly,duringitsfirstyears,blockchainwasconsideredasynonymoustoBitcoin,and

Fig.2. Flowchartofthesearchstrategy.

Fig.3. Year-wiseanalysisoftheselectedliteraturepertypeofpublication.

inprinciple,researchersweretryingtocreatetheinfrastructureratherthanusethisnewtechnologyforapplicationpurposes. Therefore,journal-orientedcontentrelatedtoblockchain-enabledapplicationshasbeennotablypublishedfrom2016onwards.From Fig.3 itisalsoevidentthatalargevolumeofscientificliteraturehasbeenpublishedinconferenceproceedings,withasteadyupward trend.

Thedomain-specificdistributionofthe260researchitemsovertimemaybeseenin

Fig.4.Elevendomainsofblockchain-based applicationshavebeenidentifiedfromtheanalysis.Business-orientedapplicationsrepresentalargeportionofallavailableapplications(58outofthe260researchitems)followedbyGovernance,IoT,andDatamanagementapplications.Health-orientedapplicationsalsoreceivemuchattentionfromthescientificcommunityduringthelastcoupleofyears. Fig.4 showsthatalthough blockchainseemedtohave,atleastatitsveryearlystages,apivotalroletoplayinfinance,theresearchcommunityisyettoproduce asubstantialamountoffinancial-orientedapplications.Moreover,therelativelylargenumberofmiscellaneousapplications(applicationsthatfalloutsidethecategoriesdescribedabove)alsohighlightstheinterdisciplinarypotentialoftheblockchaintechnology.

5.Taxonomyofblockchain-basedapplications

Mostauthorsclassifyblockchainapplicationsintofinancialandnon-financialones(Crosbyetal.,2016)sincecryptocurrencies representaconsiderablepercentageoftheexistingblockchainnetworks.Othersclassifythemaccordingtoblockchainversions(i.e., 1.0,2.0and3.0)(Swan,2015;Zhaoetal.,2016).Inthiswork,weproposeanapplication-orientedclassification,similartotheone proposedin Zhengetal.(2016).Ourapproach,however,differsfromothersimilarworksinthatitusesarigorousstatistical methodologybasedontheliterature(seeSections 3and4),andthusitfitsbettertocurrentblockchaindevelopmentsandillustrates withhighfidelitythefutureblockchaintrends.Therefore,takingintoaccounttheactualandforthcomingheterogeneityofblockchainsolutions,wepresentamorecomprehensiveandin-depthclassificationofblockchain-basedapplications,whichisgraphically representedin Fig.5.Inthefollowingsubsectionsweprovideasoundclassificationoftheavailableblockchain-enabledapplications basedontheanalysisoftheavailableliterature.

5.1.Financialapplications

Currently,blockchaintechnologyisappliedtoawidevarietyoffinancialfields,includingbusinessservices,settlementoffinancialassets,predictionmarketsandeconomictransactions(HaferkornandQuintanaDiaz,2015).Blockchainisexpectedtoplayan essentialroleinthesustainabledevelopmentoftheglobaleconomy,bringingbenefitstoconsumers,tothecurrentbankingsystem andthewholesocietyingeneral(Nguyen,2016).

Theglobalfinancialsystemisexploringwaysofusingblockchain-enabledapplicationsforfinancialassets,suchassecurities,fiat money,andderivativecontracts(PetersandPanayi,2016;FanningandCenters,2016;Nijeholtetal.,2017;Paech,2017).For example,blockchaintechnologyoffersamassivechangetocapitalmarketsandamoreefficientwayforperformingoperationslike securitiesandderivativestransaction(VandeVeldeetal.,2016;WuandLiang,2017),digitalpayments(Papadopoulosetal.,2015; Becketal.,2016;Minetal.,2016;Yamadaetal.,2017;EnglishandNezhadian,2017;Lundqvistetal.,2017;Gaoetal.,2018),loan

Fig.4. Distributionofresearchitemsaccordingtothethematicareaidentified.

managementschemes(Gazalietal.,2017),generalbankingservices(Coccoetal.,2017),financialauditing(DaiandVasarhelyi, 2017)orcryptocurrencypaymentandexchange(i.e.,e-wallets)(Cawrey,2014;Rizzo,2014).Notably,asetoftheworld’sbiggest banks,includingBarclaysandGoldmanSachshavejoinedforceswithR3(R3,2015)toestablishanoperatingblockchain-based frameworkforthefinancialmarket(Crosbyetal.,2016).AnotherexampleofbankcooperationistheGlobalPaymentsSteering

Fig.5. Mindmapabstractionofthedifferenttypesofblockchainapplications.

Group(GPSG)(Ripple,2016),whosemembersincludeSantander,BankofAmericaandUniCredit,amongothers.Thecryptocurrency behindGPSGisXRP,createdbyRipple(Brittoetal.,2012)whichimplementsaninteroperableandscalableopen-sourceinfrastructureenablingglobalpaymentsandcurrencyexchanges.

Predictionmarketplacesystems(PMS),whichserveasoraclesorinformationproviders,arealsoaninterestingfieldwhichmay impactbusinessesandcryptocurrencies.Blockchain-basedP2PimplementationsofPMScanbefoundin Viacoin(2014),anopen sourcecryptocurrencythatfeaturesScryptMergedmining,atypeofPoWthatpermitsmuchfastertransactionsthanBitcoin. Augur (2014) isadecentralisedPMSthatallowsuserstotradesharesbeforetheoccurrenceofaneventundertheparadigmofthewisdomof thecrowds.Usersarerewardedforcorrectlypredictingfuturereal-worldevents. Bitshares(2014) aredigitaltokensstoredinthe blockchainthatreferencespecificassetssuchascurrenciesorproducts.Thetokenholdersmayearninterestonmarketproducts,such asgold,oil,gasandalsooncurrencies.BitShares2.0offersastackoffinancialservicesincludingcurrencyexchangeorbanking operationsinadecentralisedblockchain-basedfashion.TheNasdaq-Citiplatform(Rizzo,2017)isaplatformthatenablesfunctionalitiessuchasrelationshipmanagementandinvestmentsforprivatecompanies. Ventures(2014) iscoinedintheblockchain2.0 platformandusestheCounterpartyprotocol,whichimplementsfinancialinstrumentsasSCs,tocreateanovelstockmarket.Another exampleisCoinsetter,aNYC-basedForextradingplatformforbitcoins(Coinsetter,2012).Plasma(PoonandButerin,2017)isanSC frameworkwhichenablestheuseofSCstoprocessfinancialactivity,aswellastoconstructeconomicincentivesforglobally persistentdataservices.

Otherfinancial-orientedareasmayincludecommercialpropertyandcasualtyclaimsprocessing,syndicatedloanscontingent convertiblebonds,automatedcompliance,proxyvoting,assetrehypothecation,andover-the-countermarket(Deloitte,2016a;F.R. Ltd,2016;InfosysConsulting,2016;McWatersetal.,2016).Finally,blockchainadoptionbythefinancialsectorwilleventuallylead tocostsavingsinareaslikecentralfinancereporting,compliance,centralisedoperations,andbusinessoperations(Accenture, 2017a).

5.2.Integrityverification

Oneofthemostemergingblockchain-relatedfieldsisintegrityverification(BhowmikandFeng,2017;Dupont,2017;Xuetal., 2017a;JamthagenandHell,2016;Zikratovetal.,2017).Blockchainintegrityverificationapplicationsstoreinformationand transactionsrelatedtothecreationandlifetimeofproductsorservices.Thepossibleapplicationsare:(i)provenanceandcounterfeit, (ii)insurance;and(iii)intellectualproperty(IP)management.

AnintegrityverificationsubsetofblockchainapplicationsarethoseorientedtoIPprotection(Kishigamietal.,2015;Kitahara etal.,2014;Fujimuraetal.,2015;DeLaRosaetal.,2017).Asstatedin Swan(2015),thetermdigitalartreferstoIPandnotjustto onlineartworks,soblockchaintechnologiescanbeconsideredtocoverallsuchscenarios(O’DairandBeaven,2017;McConaghy etal.,2017;Zeilinger,2018).MaturesolutionslikeAscribe(Ascribe,2014)andMediachain(Labs,2016)useBitcoinblockchainto linkdigitalcontentwiththeircreators.Ascribeusesittotransferownershipandloandigitalassets,whileMediachaintriestostore metadataontheblockchaintoallowmediarecoveryandquerying.MonetisationapproachessuchasMonegraph(MonegraphInc., 2014)enablesharingofrevenueacrossthevaluechainofmediadistributionforonlinebroadcasts,videoclips,imagereels,andother licensedorbrand-sponsoredcontent,previouslyverifiedintheblockchain.Factom(Snowetal.,2015)isanotherblockchainsolution forstorageandvalidationofdigitalassets.SilentNotary(SilentNotary,2017)isablockchain-basedserviceforconfirmationofevent existence,recordedinadigitalformatsuchascommunicationinmessenger,image,videofile,ande-mail.Kodakcoin(Kodaketal., 2018),isanovelapaymentmethodusedtoacquirephotolicensesandimagerightsfromathekodakOneplatform,whichstoresthe worksofregisteredphotographers.Anotherexampleofnetworkmedia’sdigitalrightsmanagementcanbefoundin Xuetal.(2017b) HerbautandNegru(2017) proposeauser-centricapproachthathelpsthenecessaryreshapingofthecontentdeliveryecosystem.

Theworkpresentedin KimandLaskowski(2016) describesanontologytostoreandinterpretdatainanautomatedway,inthe contextofdataprovenanceandintegrity.AuthorsclaimthatSCsarecloselyrelatedwithontologiesandthatsuchsystemscanbe adapteddependingonthetopic.CounterfeitsolutionssuchasEverledger(Lomas,2015)andBlockverify(Blockverify,2015)use blockchainandSCstoavoidfraudforbanksandinsurancesandtointroducetransparencytosupplychains,respectively.Further examplesondataintegritycanbefoundin Xunetal.(2017),whereauthorsimplementtherelevantprotocolsandthefollowing prototypesystemofablockchain-basedframeworkfordataintegrityserviceandin Jaagetal.(2016),whereauthorsshowhow blockchainsmaybeusedforsupplychainmanagement,identityservicesordevicemanagementinabusinesssetting.

Blockchaintechnologyisrecentlyreceivinganever-increasingattentionfromtheinsuranceindustryinavarietyofareas,includingsales,underwriting,customeronboarding,claimsprocessing,payments,assettransfers,andreinsurance(Cognizant,2017; Lambertietal.,2017;KPMGInternational,2017).Forinstance,European-basedinsurershaverecentlylaunchedtheB3i-ablockchain industryinitiativeforexploringhowblockchaincanbeusedtodevelopprocessesandstandardsforindustry-wideusageandto accelerateefficiencygainsintheinsurancesector(Cognizant,2017).SCsenabledbyblockchainleadtotheautomationofseveral processesintheinsurancesector,resultingtherebytosubstantiallyreducedcosts,increasedefficiency,andprocessingspeed (Cognizant,2017).Healthinsurance-specificpotentialimplicationsoftheblockchaintechnologymayincludetheestablishmentof moresecuredatarepositoriesformedicalandwellnessinformation,fortriggeringalertstotakeprescriptionsormakeregulardoctor visitsordiagnostictests,forfacilitatingcontinuousunderwritingandpricingassessments,forestablishinglessarbitrary,moreup-todateriskpooling,andforallowingformorepersonalisationandindividualisedcoverage(Deloitte,2016b).Moreexamplesof blockchain-basedinsuranceapplicationscanbefoundin(McKinseyCompany,2016;Nath,2016;Voetal.,2017).

5.3.Governance

Governmentsthroughoutyearsareentrustedwithmanagingandholdingofficialrecordsofbothcitizensand/orenterprises. Blockchain-enabledapplicationsmightchangethewaygovernmentsatlocalorstateleveloperatebydisintermediatingtransactions andrecordkeeping(Reijersetal.,2016;Hou,2017).Theaccountability,automation,andsafetythatblockchainoffersforhandling publicrecordscouldeventuallyobstructcorruptionandmakegovernmentservicesmoreefficient.Inparticular,blockchaincould serveasasecurecommunicationplatformforintegratingphysical,social,andbusinessinfrastructuresinasmartcitycontext(Ibba etal.,2017;Jaffeetal.,2017;BiswasandMuthukkumarasamy,2016;Sharmaetal.,2017).Blockchaingovernanceaimsatproviding thesameservicesthatareofferedbythestateanditscorrespondingpublicauthoritiesinadecentralisedandefficientwaywhile maintainingthesamevalidity.Examplesofsuchservicesincluderegistrationorlegaldocuments,attestation,identification,marriage contracts,taxesandvoting(Swan,2015).

TheWorldCitizenproject(McMillan,2014)isanexampleofadecentralisedpassportservicetoidentifycitizensalloverthe world.Blockchainscanalsobeusedtootherpublicservicessuchasmarriageregistration,patentmanagement,andincometaxation systems(Akinsetal.,2013).Otherprojectsfocusonideassuchasdelegativedemocracy,wheredelegates(insteadofparliamentary representatives)takethevotingpower(Swan,2015).Similarly,Holacracy(Robertson,2015)isacustomisableself-management practicefororganisationswhereauthorityanddecision-makingaredistributedthroughoutself-organisingteamsinsteadofrelyingon atypicalhierarchicalorganisationsetting.

5.3.1.Citizenshipanduserservices

Theintegrationofdigitaltechnologiesineverydayliferequiresmechanismsabletodetermineaccuratelywhotheusersare(Lee, 2018)andcertifytheirbasicattributeslikename,address,creditrecord,aswellasotherpersonalcharacteristics(Lemieux,2016; LeidingandNorta,2017;Augotetal.,2017;Buchmannetal.,2017).Therefore,digitalidentityhasbecomeacrucialsecurity measure(Riveraetal.,2017).In PaulDunphy(2018) theauthorsanalysethreedecentralisedidentitymanagementapproaches,

namelyuPort,ShoCardandSovrinandassesstheirbenefitsandshortcomings.Moreover,accordingto Roberts(2017),one-sixthof theworld’spopulationlackdocumentedproofoftheirexistence.Thissituationaffectsimmigrantsandrefugees,sincetheircountries mayoftenrefusetohandoverthedocumentsif,forinstance,theybelongtotheopposition.Therefore,blockchainbecomesan instrumenttoreinforceequalityandopportunitiestoworldwidecitizens.Formoreondigitalidentityandblockchain,onemayrefer to Riveraetal.(2017).

TheemergenceofTheInternetofAgreements(IoA)(Summit,2017),whichestablishestheconnectionbetweendigitalcontents (theInternet)andreal-worlddeals,contractsorregulations,enablesthenextgenerationofdigitalcommerce.Therefore,blockchain applicationsthatimplementSCstoverifymultipletypesofoperations,suchasindividualproperties,areusedtostatethecontractual relationshipsbetweentheInternetactors,beingthemcompaniesorindividuals(ChenandZhu,2017;Ishmaev,2017;Governatori etal.,2018;Herian,2017).Forinstance,Pavilion.io(Duhamel,2014)isablockchain-basedcompanythatprovidesanAPItoenablea verificationinterfacethateliminatestheneedfore-commercebuyerstoplacetrustinsellersorthird-partyproviders.Mattereum (Mattereum:SmartContracts,RealProperty,2017)isanIoAprojecttomanagelegalrightsoverphysicalandIPontheblockchain. Stampery(Stampery,2015)isacertificationcompanythatusesblockchaintocreateastampofemailsordocuments.Thissystem providesproof-of-existence(PoE),proof-of-ownership(PoO),proof-of-integrity(PoI)aswellasproofofreceiptbystoringthe transaction’sinformationinthepublicledger.IntheProofofExistence(ProofofExistence,2017)project,authorsuseblockchainto ensuretheexistenceofadocumentanditscreationdatewithoutrevealingitscontents.Likewise,VirtualNotary,Bitnotar,Blocksing, btcluck,andChronobituseblockchaintocertifythecontentsofdocumentssecurelyandverifiably(Swan,2015).Thus,wemayuse thesystemsabovetostoreproofsoftransactionsandoperationsmadebetweenindividualsand/orcompanies.Inthisregard,the increaseinonlinetransactions,suchasine-commerce,havecausedanupsurgeofdisputes.Duetotheubiquitousnatureofonline disputes,efficientconflictmanagementmustbeprovided,thatovercomescross-borderandinstitutionaloverheads.Themethodsand projectsmentionedabovepermitthecreationofefficientdisputeresolutionmethodssincetheinformationstoredintheblockchain canbeverifiedandaudited.Othermethodsandprojectsthatimplementfunctionaldisputeresolutionmechanismscanbefoundin Koulu(2016)andSwan,2015

5.3.2.Publicsector

Inthecaseofpublicservices,weconsiderthatvirtualnotary,PoE,PoO,PoI,reputationanddisputeresolutionaretypesof servicesthatcanbedevotedtocitizenswithouttheparticipationofofficialinstitutions.NotethatPoE,PoOandPoIarecloselyrelated andeasilyverifiableinablockchain.Governmentagenciesaroundtheworldarelookingforopportunitiesrelatedtotheadoptionof blockchaintechnologyinthepublicsector(DeloitteDevelopmentLLC,2017;Chiangetal.,2018),particularlyforutilisingthesecure, distributed,open,andinexpensivedatabasetechnologytoreducecostandbureaucracy,increaseefficiencyandforauthenticating manytypesofpersistentdocuments(Ølnes,2016;Nordrum,2017;ØlnesandJansen,2017;Ølnesetal.,2017).Otherblockchain applicationsinthepublicsectormayincludedocumentverification,e-residencyapproaches(SullivanandBurger,2017)thedevelopmentofmorereliableandtransparenttaxationmechanisms(Pokrovskaia,2017;Wijayaetal.,2017),thedevelopmentofmore robustregulatorycomplianceframeworks(FilippiandHassan,2016;Gerstl,2016;Engelenburgetal.,2017)andlandmanagement (Pichel,2016).

5.3.3.Voting

Forseveralyearse-votinghasbeenconsideredapromisingandinevitabledevelopmentwhichcouldspeedupvotingprocesses, simplifyandreducethecostofelections,andthedevelopmentofstrongerdemocracies(Boucher,2016).However,existingelectronic votingsystemsrelyonproprietaryandcentraliseddesignbyasingleentity,characteristicsthatharmthetrustandconfidencevoters havetothevotingprocess(MouraandGomes,2017).DecentralisedvotingsystemssuchasBitCongress(Deitz,2014)andLiquid Democracy(Schiener,2014)proposeframeworkstoenforcedistributeddecisionmaking.Futarchy(Hanson,2013)isavotingsystem whereparticipantsproposetopicsandpossiblestrategiestoachievetheminatwo-stepfashion.Moreconcretely,participantssupport policiesdependingonwhethertheprediction/bettingmarketsoptimisethegeneralrevenueforthem(e.g.benefitsincaseofaprivate companyorGDPinthecaseofacountry).Ingeneral,blockchaintechnologyoffersanopen-source,peer-to-peer,decentralisedand independentlyverifiablenetworktogaintheconfidencerequiredbyvotersandelectionorganisers(Noizat,2015;Kubjas,2017; Meter,2017;Hsiaoetal.,2018)whilebeingconsistentwithdomesticlegislation(SchulzandSchafer,2017).

5.4.Internetofthings

Around90%ofthedataintheworldtodayhasbeencreatedinthepasttwoyearsalone(IBM,2017).Suchgrowthpacewill increaseduetoa)theadventoftheInternetofThings(IoT),b)tothepopulationgrowth(Stats,2017).WhiletheexpansionpossibilitiesoftheblockchainandIoTtechnologiesarealreadyvastontheirown,thesymbioticrelationshipofthesetwofieldsarises myriadmore.Forinstance,thedistributedwirelesssensornetworks,whichdespitetheirdrawbacks(Pietroetal.,2014;Linetal., 2017)areoneofthepillarsoftechnologicalandhumanevolution,demonstratethatblockchainarchitecturemayenhanceIoTby minimisingitsdeficienciesandmaximisingitspotential(Kshetri,2017;Liaoetal.,2017;Buccafurrietal.,2017a;Fabiano,2017; ÖzyilmazandYurdakul,2017).

TheincreasingattentionandinvestmentsforimplementingdecentralisedIoTplatforms(SamaniegoandDeters,2016a;Novo, 2018;ZhangandWen,2017)aremainlydrivenbytheblockchaintechnologyanditsinherentcapabilities(Christidisand Devetsikiotis,2016).Themainideaistoprovidesecureandauditabledataexchangeinheterogeneouscontext-awarescenarios (Casinoetal.,2017)withplentyofinterconnectedsmartdevices(Crosbyetal.,2016).Moreover,operatinginanautomatedand

decentralisedfashionenablesthenetwork’shighscalabilityandefficientmanagement(Sharmaetal.,2018;LiandZhang,2017; Sakakibaraetal.,2017).

Blockchaininteroperabilityenablesindependentandsecurereal-timepaymentservices,enhancingtraditionalcommerce,ecommerceorpublicandprivatetransportationsystems(ChristidisandDevetsikiotis,2016).ThereareseveralexamplesofapplicationsthatagglomeratethesecharacteristicssuchastheFilecoin(Benet,2014),whichisamemorystorageprovider,orthe EtherAPIs(EtherAPIs,2016),whichenablesAPIcalls’monetisation.Inthefuture,IoTdevicescouldbedirectlylinkedwiththeir cryptocurrency-basedbankaccount(ChristidisandDevetsikiotis,2016)sothatmicrotransactions(Passetal.,2015)couldbeperformedinexchangeforservices(Huckleetal.,2016;Hwangetal.,2017),whilesimilarapproachesmayalsobeappliedtothesmartgriddomainforallowingtheenergysale(Rutkin,2016;Lietal.,2017b).Inthecaseofprovenanceorsupplychains,distributed networksofRFIDsensorsenabletheautomatedprocessingofproductsinmultiplecontexts,suchasinfoodsupplychains,transportationservicesorinventorymanagement(Liuetal.,2017;Shafaghetal.,2017).Inthesecontexts,theinformationmonitoredby thedevicescouldbestoredintheformofSCsortransactionsintotheblockchain.AnexampleofaP2PdistributedIoTsystemcanbe foundin(FoundationsfortheNextEconomicRevolution,2016).Theimplementationofblockchain-basedIoTsolutionscouldsolve severalissues,suchasthehighmaintenancecostofcentralisedapproaches(ChristidisandDevetsikiotis,2016;Bottaetal.,2016). Moreover,adecentralisedandsecureP2PmodelcouldincreasethesecurityofIoTandwirelesssensornetworks(Pietroetal.,2014; Dazaetal.,2017;Ouaddahetal.,2016;Ouaddahetal.,2017),enablingahighercontrolofIoTdevicesforkeepingsystemsup-todate(LeeandLee,2017;SamaniegoandDeters,2016b;Boudguigaetal.,2017;Samaniegoetal.,2017;SamaniegoandDeters,2016).

Undoubtedly,therearesomeissues,suchaslowcomputationalpowerandstoragecapabilitiesofIoTdevices,thatmaylimitthe useofBlockchain.In Buccafurrietal.(2017a) theauthorsproposeanalternativewaytoimplementapublicledgerovercomingthese drawbacksandthusenhancingIoTapplications.Otherefficientarchitecturesarepresentedin Dorrietal.(2017a)andDorrietal. (2017b) whereauthorsproposeasecurelightweightblockchain-basedarchitectureforIoTindifferentapplicationcontexts.

ThereexistotherexamplesofIoTapplications,suchastheAutonomousDecentralisedP2PTelemetry(ADEPT)(IIBM,2015) systemdevelopedbytheIBMwhichusesblockchaintobuildadistributednetworkofdevices.Filament(FoundationsfortheNext EconomicRevolution,2016)ensuressecureeconomicexchangeamongautonomousdevices.Moreover,theauthorsassignaunique identitytoeachdevicethroughablockhain-basedIoTsoftware.Inthesameline,Huhetal.(Huhetal.,2017)proposestheuseofthe EthereumplatformtoperformsecurekeymanagementinIoTcontexts.FormoreontheIoTandblockchain,wereferthereaderto (ChristidisandDevetsikiotis,2016;KhanandSalah,2017;Conoscentietal.,2016;KravitzandCooper,2017).

5.5.Healthcaremanagement

Blockchaintechnologycouldplayapivotalroleinthehealthcareindustrywithseveralapplicationsinareaslikepublichealthcare management,longitudinalhealthcarerecords,automatedhealthclaimsadjudication,onlinepatientaccess,sharingpatients’medical data,user-orientedmedicalresearch,drugcounterfeiting,clinicaltrial,andprecisionmedicine(Mettleretal.,2016;Petersonetal., 2016;Chamberofdigitalcommerce,2016;Ahrametal.,2017;AlOmaretal.,2017;Capgemini,2017;EmrifyInc.,2017;Freed Associates,2017;Shaeetal.,2017;Zhaoetal.,2017;Mamoshina,2018;Mytis-Gkomethetal.,2017;BorioliandCouturier,2018;Lee andYang,2018;Xiaetal.,2017a,2017c;Yueetal.,2016;Patel,2018;Junejaetal.,2018).Inparticular,blockchaintechnologyand theuseofSCscouldsolveproblemsofscientificcredibilityoffindings(missingdata,endpointswitching,datadredging,andselective publication)inclinicaltrials(Nugentetal.,2016)aswellasissuesofpatients’informedconsent(BenchoufiandRavaud,2017; Benchoufietal.,2017).

Managingpatients’ElectronicHealthcareRecords(EHRs)isprobablytheareawiththehighestpotentialgrowth(Liu,2016; Angraaletal.,2017;Hoy,2017;Kuoetal.,2017;Baxendale,2016).AnEHRcontainsapatient’sshortmedicalhistory,aspartofher medicalrecord,aswellasdata,predictions,andinformationofanykindrelatingtotheconditionsandtheclinicalprogressofa patientthroughoutthecourseofatreatment.AblockchainsystemforEHRscouldbeseenasaprotocolthroughwhichusersmay accessandmaintaintheirhealthdatathatsimultaneouslyguaranteessecurityandprivacy(Azariaetal.,2016;Young,2016;BurstIQ, 2017;Dubovitskayaetal.,2017;Sullivan,2017;Medicalchain,2017;Center,2017;Xiaetal.,2017b).ThebenefitsofablockchainbasedsystemforEHRsaremanifold:recordsarestoredinadistributedway(theyarepublicandeasilyverifiableacrossnon-affiliated providerorganisations),thereisnocentralisedownerorhubforahackertocorruptorbreach,dataisupdatedandalwaysavailable whereasdatafromdisparatesourcesisbroughttogetherinasingleandunifieddatarepository(GreyHealthcareGroup,2017).

5.6.Privacyandsecurity

Centralisedorganisations–bothpublicandprivate–amasslargequantitiesofpersonalandsensitiveinformation.Althoughthe GDPR(Parliament,2016)aimstoregulatetheprocessingofthisdata,thereisstillabiggaptocover(Politouetal.,2018).Blockchain isconsideredasanopportunityforenhancingthesecurityaspectsofbigdata(Puthaletal.,2018;Kshetri,2017;Cohenetal.,2017) anditsscalabilitywhencombinedwithotherefficientstoragesystemsthatimplementdataminingmethods(Bozicetal.,2016). Therefore,privacyandsecurityorientedapplicationsthatrelyonblockchaintechnologycanbefoundintheliterature(DiFrancesco Maesaetal.,2017;Dorrietal.,2017c;HariandLakshman,2016;Leeetal.,2017;Tangetal.,2018;Chansonetal.,2017;Anjum etal.,2017).

Namecoin(HaferkornandQuintanaDiaz,2015)isanopen-sourceblockchaintechnologythatimplementsadecentralisedversion ofDNS.ThemainbenefitsofadecentralisedDNSapproacharesecurity,censorshipresistance,efficiency,andprivacy.Alexandria (TheDecentralizedLibraryofAlexandria,2015)isanopen-sourceblockchain-basedprojectthatprovidesasecureanddecentralised

libraryofanykindofmediawhileallowingthefreedomofspeech.Bothsystemsmaybeenhancedutilisingdigitalidentityservices whichcanconfirmanindividual’sidentities(e.g.usingpseudonyms),enablingsecurityandanonymityinastandardisedverification model(Swan,2015;Zhangetal.,2017).In Zyskindetal.(2015a) theauthorsproposeadecentralisedP2Pblockchain-basedplatform thatcomprisesthreetypesofentities:(i)users,whichinteractwiththeapplications;(ii)services,whichprovidesuchapplicationsand processusers’personaldataforoperationalandbusiness-relatedreasons;and(iii)nodes,entitiesthatreceiverewardsinexchangefor maintainingtheblockchain.Sinceonlyhashpointersarestored,usershavecontrolovertheirdata.

Blockchaintechnologymayalsobeusedtoenhancesecurityandreliabilityindistributednetworksthroughhardwareand softwaresolutions(Fanetal.,2018;Chaetal.,2017;SuzukiandMurai,2017).Forinstance,SIRINLABS(Labs,2014)developedthe firstblockchain-basedsmartphone,capableofprovidingfast,fee-lessandsecuretransactions.BitAvisanantimalwareblockchainbasedsolution(Noyes,2018)thatenhancesviruspatterndistribution.In Axon(2015),theauthorsimplementaprivacy-awarepublic keyinfrastructure,whichenhancessecurityagainstasinglepointoffailureormaliciousattacks. Liangetal.(2018) proposetheuseof adistributedblockchain-basedprotectionframeworktoenhancethesecurityofmodernpowersystemsagainstcyber-attacks.In Xu etal.(2017c),authorsrecalltheuseofDockercontainers(Docker,2013)inIoTandtheirbenefits. Rodriguesetal.(2017) proposea novelarchitecture,whichcombinesblockchainandSCtechnologies,introducingtherebynewopportunitiesforflexibleandefficient DDoSmitigationsolutionsacrossmultipledomains,withparticularregardoninsecureportableandstationarydevices. Toshetal. (2017) discussvulnerabilitiesinblockchaincloudanditscapabilitytoenabledataprovenance.Blockchaincouldalsobeusedasa verificationprotocolforenabling,securingandauthenticatingspectrumsharingincognitiveradionetworks(KotobiandBilen,2017; Rajuetal.,2017;Niuetal.,2017).

Transactionalprivacyisoneofthemostchallengingproblemsofblockchaintechnologies.Therefore,severalmethodshavebeen proposedtoimproveanonymityofblockchains(Zhengetal.,2016)suchasmixingservices(Möseretal.,2013)orzero-knowledge proofs.Inthecaseofmixingservices,theaimistoprovidetransactionalprivacybytransferringfundsfrom N inputaddressesto M outputaddresses,sothatusersavoidalwaysusingthesameaddress.ExamplesimplementingsuchtechniqueareMixcoin(Bonneau etal.,2014),whichisalsoabletodetectdishonesttransactionbehaviours,andCoinjoin(Maxwelletal.,2013)orCoinShuffle (Ruffingetal.,2014),thatusesathirdpartytoshuffleoutputaddresses.InthecaseofZerocoin(Miersetal.,2013),transactionsand theoriginofcoinsareunlined,whileminersusezero-knowledgeproofstovalidateoperations.Animprovedversionwithstronger privacyguaranteeshidesbothtransactionamountsandtheoriginofcoins(Miersetal.,2013).

5.7.Businessandindustrialapplications

Blockchainhasthepotentialtobecomeasignificantsourceofdisruptiveinnovationsinbusinessandmanagementthrough improving,optimising,andautomatingbusinessprocesses(TapscottandTapscott,2017;Bogneretal.,2016;Yingetal.,2018).Many e-businessmodelsbasedonIoTandblockchainareemerging.Oneexamplecanbefoundin ZhangandWen(2015) whereauthors proposeabusinessmodelinwhichtransactionsbetweendevicesareperformedusingSCsonablockchain-baseddistributeddatabase. In HardjonoandSmith(2016) theauthorsproposeaprivacy-preservingsystemthatusesanIoTnetworkandblockchaintoprove provenancemanufacturingwithoutthethirdpartyauthentication.

Blockchainapplicationsappeartoofferconsiderableperformanceenhancementandcommercialisationopportunities(White, 2017;Klemsetal.,2017;Kogureetal.,2017),improvingcredibilityine-commerceandenablingIoTcompaniestooptimisetheir operations(Xuetal.,2017b;YooandWon,2018)whilesavingtimeandcost(IBMCorporation,2016).Blockchain-basedapplications couldserveasdecentralisedbusinessprocessmanagementsystemsforseveralenterprises.Insuchcases,eachbusinessprocess instancemaybemaintainedontheblockchain,andtheworkflowroutingcouldbeperformedbySCs,therebystreamliningand automatingintra-organisationalprocessesandreducingcost(Weberetal.,2016;López-Pintadoetal.,2017;Prybila,2017;Rimba etal.,2017;Mendlingetal.,2018).

5.7.1.Supplychainmanagement

Blockchaintechnologyisexpectedtoincreasetransparencyandaccountabilityinsupplychainnetworks,thusenablingmore flexiblevaluechains(Ahrametal.,2017;Kshetri,2017;Kshetri,2018;O’Leary,2017).Inparticular,blockchain-basedapplications havethepotentialtogeneratebreakthroughsinthreeareasinsupplychains:visibility,optimisation,anddemand(IBMCorporation, 2016).Blockchaincanbeusedinlogistics,identifyingcounterfeitproducts,decreasingpaperloadprocessing,facilitatingorigin tracking(HackiusandPetersen,2017;Kennedyetal.,2017;LeeandPilkington,2017;Toyodaetal.,2017;Tanetal.,2018)and enablingbuyersandsellerstotransactdirectlywithoutmanipulationbyintermediaries(Subramanian,2017).Moreover,ithasbeen demonstratedthattheusageofblockchain-basedapplicationsinsupplychainnetworkscansafeguardsecurity(Dorrietal.,2017a), leadtomorerobustcontractmanagementmechanismsbetweenthirdandfourthpartylogistics(3PL,4PL)forcombatinginformation asymmetry(Polimetal.,2017),enhancetrackingmechanismsandtraceabilityassurance(ApteandPetrovsky,2016;Tianetal., 2016;DüdderandRoss,2017;HeberandGroll,2017;LuandXu,2017;Tian,2017),providebetterinformationmanagementacross theentiresupplychain(InfosysLimited,2017;O’Learyetal.,2017;TurkandKlinc,2017),foodsafety(AhmedandBroek,2017), enhanceIPprotection(HerbertandLitchfield,2015;Hollandetal.,2017;Tsaietal.,2017),offerbettercustomerservicethrough advanceddataanalytics(i.e.encryptedcustomerdata)andnovelrecommendersystems(Freyetal.,2016a;Freyetal.,2016b), improveinventoryandperformancemanagementacrosscomplexsupplychains(MadhwalandPanfilov,2017),andfinally,itcan improvesmarttransportationsystems(YuanandWang,2016;Leietal.,2017;Leidingetal.,2016)andoffernewdecentralised manufacturingarchitectures(SyncFab,2018).

5.7.2.Energysector

Thepotentialapplicationsofblockchainintheenergysectorarefar-reachingandmayhaveanenormousimpactbothintermsof processesaswellasplatforms(Bilaletal.,2014).Forexample,blockchainmayreducecostsandenablenewbusinessmodelsand marketplaces,canbettermanagecomplexity,datasecurity,andownershipalonggrids,canengageprosumersintheenergymarket actingasenablerforthecreationofenergycommunities(Mengelkampetal.,2018;Wuetal.,2017;Danzietal.,2017),canenhance thetransparencyandtrustoftheenergymarketsystem,canguaranteeaccountabilitywhilepreservingprivacyrequirements,can enhancedirectpeer-to-peertradingtosupportthesmoothoperationofthepowergrid,andcanbetterhandledemandresponseand provideaframeworkformoreefficientutilitybillingprocessesandtransactiveenergyoperations(DeutscheEnergie-AgenturGmbH, 2016;Ioannisetal.,2017;PricewaterhouseCoopersandWirtschaftsprungsgesellschaft,2017;EnergyWebFoundation,2018; KyriakarakosandPapadakis,2018).Blockchaintechnologymayalsobeusedforissuingcertificatesoforigin,particularlyforgreen energyproductionandrenewableenergysources(Castellanosetal.,2017;Tanakaetal.,2017;Houetal.,2018;Parketal.,2018; Patiletal.,2018),fordevelopingpeer-to-peerenergytransactionsschemes(Chengetal.,2017;Imbaultetal.,2017;Mylreaand Gourisetti,2017a;MylreaandGourisetti,2017b;Sikorskietal.,2017;Popetal.,2018)andforestablishingenergymanagement schemesforelectricvehicles(Kimetal.,2017;Knirschetal.,2018;Knirschetal.,2017;Huangetal.,2018).Itisalsoworth mentioningthatblockchainisconsideredanenablerforthedecarbonisationoftheenergysectorfacilitatingitsmovetowardsmore decentralisedenergysources(WorldEnergyCouncilandPricewaterhouseCoopers,2018).

5.8.Education

Blockchaincansolveissuesofvulnerability,security,andprivacyinthecaseofubiquitouslearningenvironments(Bdiwietal., 2017)andcanbeusedforstoringeducationalrecordsrelatedtoreputationalrewards(SharplesandDomingue,2016a;Turkanović etal.,2018). SharplesandDomingue(2016b) proposetheuseofablockchain-baseddistributedsystemforeducationalrecordand reputation.Similarreputationsystemsareshownin Carboni(2015)andDennisandOwen,2015.In Devine(2015),teachersadd blocksintotheblockchainstoringthelearningachievementsofstudents.Educationalcertificatemanagementcanalsobeenhanced byblockchainimprovingdatasecurityandtrustindigitalinfrastructures(Xuetal.,2017d),andforcreditmanagement(forinstance, relevanttotheEuropeanCreditTransferandAccumulationSystem-ECTS)(Turkanovićetal.,2018).Moreover,blockchain-based applicationscouldenhancethedigitalaccreditationofpersonalandacademiclearning(Grechetal.,2017).Blockchain-enabled schoolinformationhubscouldalsobeestablishedforcollecting,reporting,andanalysingdataaboutschoolsystemsforsupporting decision-making(Boreetal.,2017).Finally,inthecaseofscholarlypublishing,blockchaincanbeusedeitherforbetterhandling manuscriptsubmissionsandforconductingsuitablereviewsinatimelyfashion(Spearpoint,2017)orformanuscriptverification (Gippetal.,2017).

5.9.Datamanagement

Datamanagementisoneofthemostindisputablepropertiesoftheblockchain.Implementationsandapplicationsbasedonthis technologyhavenotonlyenhanceddatamanagement(AsharafandAdarsh,2017)buthavealsofacilitatedbydefaultauditability (SuttonandSamavi,2017;Neisseetal.,2017)sincealloftheiroperationsareverifiable.Inthislastblockchain-basedapplications sectionweciterelevantliteraturethataimsatefficient,secureandverifiabledatamanagement(Zhang,2016;Jinetal.,2017).

Althoughcross-organisationalmanagementhasnotyetreachedalevelthatenablesfullinteroperabilitybetweenparties,several examplesofcross-organisationaldatamanagementcanbefoundintheliterature.In Fridgen(2018) theauthors,inajointeffortwith aGermanBank,followtheDesignScienceResearchapproach(HevnerandChatterjee,2010)todesign,implement,andevaluatea blockchainprototypeforcross-organisationalworkflowmanagement.TheresultsareencouraginganddemonstratethatBlockchain hasthepotentialtoserveasaninfrastructureforcross-organisationalworkflowmanagement.Hawk(Kosbaetal.,2016)isaframeworkforbuildingprivacy-preservingSCsthatenablesprivacy-awareintermediatecomputationstoavoidorminimiseseveral typesofdisclosures,suchastransactionalprivacy.Authorsalsoprovideanalgorithmicframeworktoenablecodingfunctionsthat willbeparsedintroprivateandblockchaincompliantprotocols.

Blockchainalsodisruptsthehumanresourcearea(Ahmed,2018;O’Learyetal.,2017;Wangetal.,2017),byenhancingdata storage(Wangetal.,2018)andselectionprocesses,e.g.auditablecandidateselectionandverifiableparticipants’data.

Inthecaseofsecuredatadistributionandmanagementsolutions, García-Barriocanaletal.(2017) proposetheuseofadecentralisedblockchain-basedsolutionformetadatasupportingkeyfunctionsanddiscussitsimplicationstowardsmanagementand sustainabilityofdigitalarchives. Yangetal.(2018) stresstheimportanceoftrustinthebigdataareaandpresentacrediblebigdata sharingmodelbasedonblockchaintechnologyandSCtoensurethesafecirculationofdataresources. DoandNg(2017) proposea systemthatenablessecureanddistributedclientdatamanagementusingcryptographicprimitivesaswellasakeywordsearch service.Besides,thedataownercangrantsearchandreadpermissionoftheirdatatothirdparties.Similarly,Searchain(Jiangetal., 2017)isablockchain-basedkeywordsearchsystemthatenablesefficientoblivioussearch(theuserknowsthechosenkeywordand thecorrespondingciphertext,buttheyareunknowntothedatasupplier)overanauthorisedkeywordsetinthedecentralisedstorage. Moreexamplescanbefoundin Zyskindetal.(2015a)andAzariaetal.(2016) inwhichsystemsthatenableblockchain-based decentralisedsensitivedatadistributionwithPoOaredescribed.Othersecuredatasharingapproachescanbefoundin Hull(2017), Fukumitsuetal.(2017),Kiyomotoetal.(2017),Hasnainetal.(2017)andKarafiloskiandMishev(2017b).Notethataccesscontrol andauthenticationmechanismsmayalsobeusedtoensureprivacyandsecurityindatadistribution(Kalraetal.,2017;Lietal., 2017c).

Cloud-baseddecentralisedandefficientsolutionsthatuseblockchaintechnologycanalsobefoundintheliterature(Shettyetal., 2017;Gaetanietal.,2017;Liangetal.,2017).Suchsystemsaimatovercomingbigdatachallenges(KarafiloskiandMishev,2017b; Yueetal.,2017)toenabletheanalysisoflargevolumesoftransactions(Abdullahetal.,2017;Xuetal.,2018;ChenandXue,2017).

5.10.Miscellaneousapplications

Thissubsectionreferstoresearchdescribingblockchain-basedapplicationsthatfalloutsidethedomainsmentionedabove.For example,crowd-fundingplatformsarestartingtouseblockchain(BracamonteandOkada,2017;Buccafurrietal.,2017b;Zhuand Zhou,2016).Swarm,Lighthouse,andbitFylerareexamplesofcryptocurrencycrowdfundingplatforms(Swan,2015;Lietal.,2017). Blockchainapplicationsmayalsobefoundinthehumanitariansectorandphilanthropy(Mazet,2017),particularlyasameansof fightingpoverty(Kewelletal.,2017;Kshetri,2017;Pilkingtonetal.,2017;Zhouetal.,2017;Larios-Hernández,2017;Jayasinghe etal.,2017;Accenture,2017b;KoandVerity,2016).Blockchaincanalsobeusedtobuildintelligent,secure,distributedand autonomoustransportsystemsinsmartcitiescontexts(Marsal-Llacuna,2017;Sharmaetal.,2018;Adametal.,2017)ortomanage eventticketssecurely(Tackmann,2017).Blockchainisexpectedtoplayapivotalroleinenvironmentalmanagement(Saberietal., 2018;Khaqqietal.,2018).Forinstance,blockchaincouldbeusedasanovel“emissionlink”systemwithinEmissionTrading Schemes(Fuetal.,2018).Anotherinterestingapplicationmaybefoundinthecontextofsocialmedia(FuandLiri,2016;Sarretal., 2015;deSoto,2017).Inparticular,user-centricblockchainapplicationscouldenableend-userstocontrol,traceandclaimownership ofeverypieceofcontenttheyshare(ChakravortyandRong,2017).OfparticularinterestaresomeIT-orientedblockchainapplicationslike,forexample,edgecomputingandtheestablishmentofcomputationalresourcesharingsystems(Hongetal.,2017; Stanciu,2017),gridcomputing(GattermayerandTvrdik,2017),cloudcomputing(Xiangetal.,2017),andtheuseofblockchainasa softwareconnector(Xuetal.,2016;TeslyaandSmirnov,2018).Finally,blockchaintechnologymayalsoimprovesocialsharing dynamics(Pazaitisetal.,2017).

6.Openissuesandfuturetrends

Fromtheanalysisoftheselectedliterature,aseriesofinsightscanbederivedconcerningthelimitationsoftheblockchain technologyanditsusabilityacrossawideareaofdomains.AsdescribedinSection 5,blockchainisnowadaysadoptedinmany researchfieldsandbusinessareas,providinglimitlessopportunitiesforexploration.However,likeanyotheremergingtechnology, issuesandchallengesarise.Inthissection,wediscusscertainlimitationsoftheblockchaintechnology,andwedevelopseveral avenuesoffruitfulareasforfurtherresearchdirections.

6.1.Suitabilityofblockchain

Companiesacrossdifferentsectorsareexcitedaboutblockchaintechnologyanditspotentialtodrivetheirdigitaltransformation whilesolvingreal-lifeproblems(Umeh,2016).Nevertheless,whileseveralITspecialistsenvisagetheusageofblockchaininalmost everyproject,theydonotquiteunderstandthefundamentalreasonsforusingit,particularlyfromadatamanagementperspective. Forinstance,ifnodataneedstobeeverstored,blockchainwillnotaddanyvaluetoalreadyestablishedtechnicalsolutions.Similarly,ifonlyonewriterinagivensystemisforeseen,ablockchainwillnotprovideadditionalguaranteescomparedtoaregular databasewhichwouldmostprobablybeamoreappropriatechoice,particularlyfromaperformanceperspective(transactionsspeed) (Greenspan,2015c).Ontheotherhand,blockchainissuitablewhenonerequiresatransactionbetweentrustlesssourcesora permanenthistoricalrecord.Forinstance,ifthereisaneedformultiplemutuallymistrustingentitiestointeractandchangethestate ofasystem,thenblockchainmaybeaviablesolution(WüstandGervais,2017).

Therefore,beforeadoptingblockchain-enabledsolutionsoneshouldexaminethesuitabilityoftheblockchaintechnologyagainst theusecasesrequirements(Loetal.,2017).Alimitednumberofframeworkshavebeendevelopedinthescientificliteraturefor assessingthesuitabilityofblockchain-enabledapplications.Forexample,in Loetal.(2017) theauthorsproposeanevaluation frameworkforblockchain-enabledapplicationsinspecificindustrialdomainslikesupplychain,EHRs,identitymanagement,andthe stockmarket.In WüstandGervais(2017) ananalysisisprovidedrelatedtothepropertiesofdifferentblockchaintypes(i.e.,permissionedandpermissionless)andamethodologicalframeworkisdevelopedforidentifyingthesuitabilityofblockchain-enabled applicationsacrossseveraldomains.

Databasesarebytheirverynature mutable whereapredefinedsetofentitieshaveaccessandmayinsertorupdatedata.These entitiesmayhavespecificroles,buttheiridentitiesareknown.However,thereareadministrativeroleswhichmaycompletelyalter thecontentsandstructureofthehostedinformationregardlessofwhethertheyarecentralisedornot.

Basedonthefindingsofourresearch,wehighlighttherequirementsofeachsector,see Table3,andwedevelopedaframework (Table4)toevaluatethesuitabilityofblockchain-basedsolutions.Moreconcretely,weevaluatethepotentialofblockchainagainst traditionaldatabasesinfourmaindomainareas:requiredtrustassumptions,contextrequirements,performancecharacteristicsand requiredconsensusmechanisms.Anintuitivethree-levelscale(i.e.,low,mediumandhigh)isusedtomeasuretherelevanceofeach prerequisite.Theframeworkactsasacomprehensivetoolforpractitionersaspiringtoevaluatewhethertheirsystemswillbeenhancedbyblockchainornot.Intermsoftrustness,blockchainavoidstheuseoftrustedthirdparties,onwhichdatabasesrelyon,and thus,enhancesreliabilityandverifiabilityofcontents.Blockchainisalsosuitablewhentransactionsandoperationsneedtobetraced (sequentialchainofevents)orwhenoperationsrequirestrongsecurityandprivacy(centraliseddatastructuresaremorevulnerable tomaliciousattacksthandecentralisedstructures(Zyskindetal.,2015b)).Regardingmaintenance,blockchainmayprovidea

Table3

Characteristics/requirementsthatenable/requireeachfamilyofblockchainapplications.Check(✓)denotesthatthisrequirementismandatory while denotesthatitdependsonthecase.

Table4

Analysisofattributesandprerequisitesofblockchainversustraditionaldatabases.

AttributesPrerequisites&determinants

significantcostreductionsinceitdoesnotrequirehosting.Finally,consensusmechanismsimplementedinblockchainnetworks (NguyenandKim,2018)enablemultiplewriterstomodifythedatabaseandprovideanauthoritativetransactionloginwhichall nodesprovablyagree.

6.2.Latencyandscalability

Mostcryptocurrencieshavealowtransactions’rate.Forinstance,Bitcointransactions2 cannotbyanychancecomparetosystems likeVISA’screditcardprocessingnetworkthatconstantlyhandlesupthousandsoftransactionspersecond.Undoubtedly,thebroad adoptionofcryptocurrenciesneedstoaddressthislatencyissueaswell(Swan,2015).NotethateachBitcoinblockisprocessedin approximately10minwhich,alongwiththeassociatedsecuritychecks(e.g.toavoidthedouble-spentattackinthesubsequent transactions),resultsineachtransactionconfirmationtolastuptoseveralminutes3.Therefore,blockchainarchitecturesfaceserious latencyissueswhichmaybeprovedmoresignificantastheyevolve.Privateblockchains,ontheotherhand,althoughtheyareindeed farmoreefficient,theyhavenotreachedtherequiredstandards.

Datastorageoptimisationexamplesmayalsobefoundintheliterature.In Bruce(2013),authorsproposeaschemewhereold transactionrecordsareremovedbythenetworkandatree-structureddatabasebalancesallnon-emptyaddresses.Hence,thenumber oftransactionsstoredbythenodesisdecreased,therebyimprovingthetransactionvalidationstep.In Eyaletal.(2016),theauthors proposedBitcoin-NextGenerationwherethecoreideaistodecoupleablockintotwoparts:thekeyblockforleaderelectionand

2 https://blockchain.info/charts/transactions-persecond

3 https://blockchain.info/charts/avg-confirmation-time.

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Dorat, Jean, 72, 163

Drama, 12, 87, 133-154, 190

Dramaturgy, 6, 134, 137

Dryden, 13, 132

Du Bellay, seeBellay

Duetrattati(Camillo), 55

Eclogues, 81 ff.

EducationofChildren(Montaigne), 233

Egger, Émile, 21n, 23n, 202

ElizabethanCriticalEssays(Smith), 180

Elizabethan drama, 12, 133, 144 ff., 152, 190

Elocutio, 54

Elyot, Sir Thomas, 227, 231

Empedocles, 184

Encomium, 55, 72, 75, 90, 111, 112, 131, 188

Endymion(Lyly), 152

English language, 36-38

English lyric, 66

Epithalamion(Spenser), 74, 77

Erasmus, 17, 40n, 42, 49, 54, 57, 63, 83, 98, 173, 204, 226, 231

EssayonSatire(Dryden), 132

Essays, 223-39

Estrif, 42

Étienne (printers), 9

Étienne, Henri, 21, 23, 34

Etymologiae(Isidore of Seville), 10

Euphues(Lyly), 200

Euphuism, 198, 200, 222

Euripides, 53, 61, 138, 139, 144, 165

Euryalus, 157

Eusebius, 39

Everaerts, Jan, seeSecundus

Exempla, 131, 194, 196, 231, 232

Exordium, 60

Fabliau, 109, 120, 134, 190, 194, 196

Fabri, Pierre, 68

Fabricadelmondo,Della(Alunno), 31

FaerieQueene(Spenser), 77, 123, 128-32, 152

Fenton, 198

Fiammetta(Boccaccio), 60

Fichet, Guillaume, 7

FonsBandusiae, 72

Fracastoro, Girolamo, 162, 163, 170, 179

FrameoftheWorld,The(Alunno), 31

French language, 31-36

Gaguin, Robert, 7

Gallus, Cornelius, 87

Garnier, Robert, 53, 139-44, 150, 151, 153

Gascoigne, George, 180

GawainandtheGreenKnight, 96

Genealogiadeorumgentilium(Boccaccio), 23

Geoffrey of Monmouth, 9

George of Trebizond, 53

Georgics(Vergil), 165

Gerlandia, Johannes de, 15

Gerusalemmeliberata(Tasso), 7, 53, 123, 124-27

GestesensemblelaviedupreulxchevalierBayard(Champier), 93

Giovanni di Virgilio, 82

Giraldi Cinthio (Giovan-Battista Giraldi), 195-97

Golden Age, 87, 89

GoldenAss(Apuleius), 93

GoldenLegend, 9

Googe, 181

Governour,The(Elyot), 227

Grandeetvraieartdepleinerhétorique(Fabri), 68

Gray, Thomas, 74

Greek dramaturgy, 6, 134, 137

Greek exiles in Italy, 20

Greek language, revival, 5 ff., 19-27, 35

Greek Literature, 7, 78, 79, 90, 137, 145, 179, 188

Greek oratory, 40

Greene, Robert, 201

Grotesque, 101, 106

Gryphius, 9, 13

Guarini, 148 ff.

Guarino da Verona, 20, 210

Guicciardini, 228

Gyroneilcortese(Luigi Alamanni), 96

Harvey, Gabriel, 183

Hecatommithi(Giraldi Cinthio), 195-97

Heinsius, 138

Heliodorus, 79, 188

HenryV(Shakspere), 146

Heptameron(Marguerite de Navarre), 14, 194

Hermes Trismegistus, 20

Hermogenes, 21, 55, 63, 79, 160, 170, 171, 188

Herodotus, 92, 214

Hesiod, 181

Hippocrates, Aphorisms, 211

Hippolyte(Garnier), 141

Historiarumflorentini(Bruni), 214-17

History, 213-22

History plays, 144-46

HistoryofKingRichardtheThirde,The(More), 217-20, 226

Homer, 7, 20, 22, 58, 96, 156, 157, 160, 165, 168, 173, 184, 185

Hooker, Richard, 52, 220

Horace, 65, 71, 72, 73, 86, 87, 114, 131, 156, 160, 161, 166, 168, 169, 170, 174, 179, 180, 181, 182, 189; “Ars poetica,” 10, 15, 133, 155, 158, 161, 163, 164, 165, 171, 186, 188

Howard, Henry, Earl of Surrey, 13, 37, 67, 180, 181

Hugh of St. Victor, 9

Humanism, 14, 17-19, 30, 39, 71, 82, 137, 138

Humanistic Latin tragedy, 139

Humbert, Louis, 34n

Hypnerotomachia(Colonna), 25, 202, 209

Ideadeltheatro,L’(Camillo), 56

Ideas(Hermogenes), 55

IdyllsoftheKing(Tennyson), 93

Imaginary addresses, 40

ImitatioChristi, 52

Imitation, 19, 39-90, 187

Imitationepoetica,Della(Partenio), 169-71

Inventio, 53, 54, 60, 63, 176

Isidore of Seville, 10

Isocolon, 200

Isocrates, 21

Isopet, 10, 81

Istoriefiorentine(Macchiavelli), 220-22, 224

Italian language, 27-31, 35

Italian orations, 40

Jardindeplaisance,Le, 10

Jean d’ Arras, 95

Jephthes(Buchanan), 138, 139

JerusalemDelivered(Tasso), 7, 53, 123, 124-27

John of Salisbury, 8, 42, 45

Johnson, Samuel, 42, 212

Jonson, Ben, 89

Juifves,Les(Garnier), 143

Junta, 9

Kelso, Ruth, 162

Labé, Louise, 13, 71

Ladislaus, King, 39

Lancaster, H. C., 142n

Landriani, Gherardo, 44

Latin language, 6, 7, 14, 17, 26, 27, 46, 155, 216, 232

Latin literature, 5, 17-19, 39, 41, 45, 46, 65, 79, 134, 138, 139

Lemaire, Jean, 31, 65, 68, 69, 71

Letters, 39, 41, 42

Libanius, 21

LiberTheoduli, 82

Livy, 21, 63, 213, 214

Lodge, 179n

Longueil, Christophe de (Longolius), 46, 50, 57, 59

Longus, 23, 79

Loyola, 210

Lucan, 10, 79, 174

Lucian, 93, 226

Lucretius, 26, 58, 87, 236

Lumby, J. R., 217

Lydgate, John, 67

Lyly, John, 38, 152, 153, 181, 200

Macchiavelli, 10, 12, 178, 213, 216, 220-24, 229, 231, 232

Macrobius, 188

Maggio, Vicentio, 159

Mair, G. H., 62

Malory, Sir Thomas, 11, 36, 37, 91-99, 103, 105, 107, 130

Manilius, 58

Mantuan (Baptista Spagnolo), 82, 88, 89, 180

Manuals, 15, 53

Marc-Antoine(Garnier), 141

Marguerite de Navarre, 14, 194

Marionettes, Carlomagno, 100

Marlowe, Christopher, 137, 146

Marot, Clement, 65, 67, 70, 75, 90

Martial, 70

Martianus Capella, 10

Matthieu de Vendôme, 10

Medea(Euripides), 138, 139

Medici, Cosimo dei, 12

Medici, Lorenzo de’, 147n

Melanchthon, 179, 228

Melodrama, 12, 144

Mélusine(Jean d’ Arras), 9, 95

Memoria, 54

Menander, 170

MerchantofVenice(Shakspere), 146

Metamorphoses(Ovid), 185

Methodusadfacilemhistoriarumcognitionem(Bodin), 228

Metric, 180

Michael Angelo, 29

MidsummerNight’sDream(Shakspere), 153

Migne, 42n

Mignonne(Ronsard), 77

Milton, 132, 144

Minturno, 13, 15, 44n, 164-69

Miracle, 133, 134, 135

Miracle plays, 7

Montaigne, 18, 23, 178, 232-39

Montano, Cola, 222

Montemayor, 186n

More, Sir Thomas, 17, 37, 217-20, 226

Morgantemaggiore(Pulci), 100-102

Morted’Arthur(Malory), 92, 98-99

Mortier, Alfred, 152n

Muret, Marc Antoine, (Muretus), 41, 50, 179

Muzio, 161-62

Mystère, 133, 134, 135

Mythologiae(Conti), 23

Mythology, 23, 77, 87, 147, 198

Naenia(Pontano), 66

Narratio, 60, 64, 220

Narrative, prose, 190-222

Nativity(York), 137

Navagero, 67, 170

Nemesianus, 87

Neo-Platonists, 7, 20

Nepos, Cornelius, 93

Nicoli, Nicolao, 12

“Nizolian paper books,” 46

Novella, 14

Novelle(Bandello), 190-94, 198-99

ObservationsonPetrarch(Alunno), 31

ObservationsontheVernacular(Dolce), 30

OdetoMicheldel’Hospital(Ronsard), 73

OdetotheKingonthePeace(Ronsard), 73

Odes, Pindaric, 72 ff.

Odyssey(Homer), 185

OldWives’Tale(Peele), 152

OratioinexpositioneHomeri(Poliziano), 22

Orationesclarorumvirorum, 40

Orationesobscurorumvirorum, 40n

Orations, 39, 40, 41, 61

Orator(Cicero), 44, 45

Orfeo(Poliziano), 147

Orlandofurioso(Ariosto), 111-23, 142, 168

Orlandoinnamorato(Boiardo), 93, 102-11

Ovid, 23, 58, 65, 71, 72, 79, 86, 87, 160, 174, 180, 181, 185

Padelford, F. M., 171n

Pagan terms used for Christian religion, 49

Pageantry, 87, 133

PaladinidiFrancia,I, 100

Pantagruel(Rabelais), 207, 211

ParadiseLost(Milton), 132

Parison, 200

ParlementofFoules(Chaucer), 70

Parody, in Rabelais, 204

Paromoion, 200

Partenio, Bernardino, 169-71, 188

Partitionesoratoriae(Brocardo), 63

Pastoral, 78-90, 146-54

Pastorfido,Il(Guarini), 148 ff.

Patrizzi, Francesco, 61, 184

Peele, 152, 153

Peletier, Jacques, 163-64

Pellissier, Georges, 186

Périon, 33

PetitePallaceofPettieHisPleasure,A(Pettie), 199

Petrarch, 5, 6, 13, 20, 27, 28, 29, 30, 31, 32, 37, 60, 65, 66, 67, 68, 69, 71, 82, 87, 114, 161, 162, 168, 170, 177, 179, 188, 222, 237

Petrus Comestor, 10

Pettie, William, 199

Pharmaceutria, 58, 81

Pico, 170

PiersPlowman, 131

Pilgrim’sProgress, 52

Pindar, 71, 72, 79, 168, 179

Pindarics, 72 ff.

Plantin, Christophe, 9

Plato, 7, 20, 25, 26, 43, 44, 62, 63, 165, 178, 179, 226

Platonic dialogue, 43, 61

Platonism, 25, 61

Plattard, J., 210n, 211n, 212n

Plautus, 58, 134, 147, 151

Plays, sacred, 134-37

Pléiade, 32, 37, 65, 69, 70, 71, 74, 119, 163, 175, 183, 186, 204

Pliny, 26, 198

Plutarch, 23, 63, 140, 179, 208, 238

Poemaeroico(Tasso), 176

Poetic, confusion with rhetoric, 15, 188

Poetic(Aristotle), 15, 25, 158, 164, 176, 189, 238

Poetica(Scaliger), 4, 171-75

Poetica(Trissino), 67, 158

Poeticadialogus(Fracastoro), 162

PoeticadiFrancescoPatrici..., 184

PoeticadiJasonDenores, 185

Poetics, sixteenth-century, 155-89

Politics, discussions on, 223-32

Poliziano, 22, 41, 47-49, 50, 57, 87, 166, 226

Pollio(Vergil), 81

Pontano, 58, 66, 72, 170, 179

PontusandtheFairSidoine, 9, 95

Porcari, Stefano, 221

Porcie(Garnier), 139

Praelectio, 41, 47, 50

PreëminenceoftheFrenchlanguage(Étienne), 34

Principe(Macchiavelli), 223

Printers, 9

Printing, effect on literary progress, 5, 9, 30, 231

Priscian, 10

ProjectdulivreentituléDelaprécellencedulangagefrançois (Étienne), 34

Pronuntiatio, 54

Propertius, 87

Prose(Bembo), 28

Prose forms, imitation of, 39-64

Prose narrative, 190-222

Prosopopoeia, 40

Prothalamion(Spenser), 74

Provençal, 28, 36, 66

Proverbia(Alain de Lille), 10

Publishers, 9, 13

Pulci, Luigi, 100-102, 109

Puttenham, 182, 183

Quintilian, 15, 47, 53, 55, 62, 63, 163, 164, 236n, 238

Rabelais, François, 22, 25n, 37, 202-13, 239

Ragionamentidellalinguatoscana(Tomitano), 59

Raphael, 29

Ratiostudiorum, 64

Religion, in Tasso and Spenser, 123, 124

Rerumscoticarumhistoria(Buchanan), 216

Retorica,Della(Patrizzi), 61

Retorica,La(Cavalcanti), 63

Rhetoric, confusion of poetic with, 15;

of Hermogenes, 188; recovery of Cicero’s works on, 44; Renaissance preoccupation with, 41

Rhetoric(Aristotle), 62, 63

Rhetoric(Soarez), 64

Rhetorica(Joannes Caesarius), 55

Rhetorica(George of Trebizond), 53

RhetoricaadHerennium, 10, 45, 63

Rhetorics, 53-64

Rhétoriques, 68

Rhétoriqueurs, 65, 68

Rhythm, English tradition of, 180

Ricci, Bartolomeo, 40, 40n, 50, 57

RichardIII(More), 217-20, 226

RichardIII(Shakspere), 146

RichesoftheVernacular,The(Alunno), 31

RimediversedelMutioIustinopolitano...(Muzio), 161-62

Robinson, Edwin Arlington, 93

Robinson, Ralph, 226

Romance, 91-132;

Arthurian cycle in Malory, 98; Carolingian cycle, 100, 101, 124; Greek, 7, 90, 179, 188; separate romances, 95-98

RomandelaRose, 70

Romantic contrast, 91-95

Ronsard, Pierre de, 10, 21, 23, 34, 35, 65, 67, 71-75, 77, 113, 119, 163, 175, 179, 188, 238

Round Table stories, 98, 108

Rouville, 13

Ruddiman, Thomas, 230n

Ruskin, John, 62

Rustic and pastoral comedy, 146-54

Ruzzante (Angelo Beolco), 150 ff.

Sacred plays, 133-37

Sacrerappresentazioni, 134

Sallust, 18, 58

SamsonAgonistes(Milton), 144

Sannazaro, Jacopo, 83-87, 165, 170, 179

Sansovino, Francesco, 40

Sappho, 87

Satire, of Rabelais, 207

Scaliger, Joseph, 137, 138, 188, 216

Scaliger, Julius Caesar, 4, 23, 171-75, 179

Scève, Maurice, 13

Schemata, 200

Scholars, gentlemen, 187

Scholemaster(Ascham), 38n

Scotorumhistoriae(Boece), 216

SecundaPastorum, 137, 150

Secundus, Joannes, 66, 72

Seneca, 10, 21, 87, 133, 134, 137, 142, 144, 145, 146, 158, 159, 165, 166, 179, 234, 238

Sententiae, 221

Shakspere, 145, 146, 147, 150, 153, 196

Shaksperian sonnet, 68

Shepherd’sCalendar(Spenser), 88-90

Sidney, Sir Philip, 46, 77, 89, 90, 178-80, 181, 188, 189, 202

Sidonius, 10, 188

Silius Italicus, 174, 188

SixLivresdelarépublique,Les, (Bodin), 230

Skelton, 37, 67, 202

Smith, G. Gregory, 180, 182

Soarez, 64

Solerti, Angelo, 87, 176

Sonnet, 66, 68, 77

Sophistic, 21, 40, 53, 55, 188, 200

Sophocles, 20, 21, 61, 142, 144, 165

Spagnolo, Baptista (Mantuan), 82, 88, 89, 180

Speculum(Vincent of Beauvais), 10

Spenser, 9, 13, 14, 24, 37, 73, 74, 75, 77, 88-91, 111, 123, 12732, 152, 180, 181, 183

Speroni, Sperone, 26, 43, 59, 60

Sprague, Arthur C., 183n

Statius, 10, 47, 87, 142, 174, 185, 188

Status, 54

Stephen of Tournay, 42n

Stoer, Jacobus, 228

Story-tellers, street, 100, 101

Story-telling, seeTales

Strowski, F., 233n

Style, literary preoccupation with, 18, 29, 52, 137

Suppositi,I(Ariosto), 147

Surrey, Henry Howard, Earl of, seeHoward, Henry

Tacitus, 41, 50, 213, 214, 223

Tales, 190-202

Tamburlaine(Marlowe), 146

Tasso, 7, 30, 52, 87, 91, 123-27, 148, 150, 153, 176-78, 184, 185, 189, 238

Tatius, seeAchilles Tatius

Tennyson, 93

Terence, 58, 134, 147, 170

Theocritus, 58, 79, 81, 86, 87, 88, 173

Theodulus, 82

Thesaurus, 46

Three styles, 15, 165, 166, 177

Thucydides, 21, 63, 213, 214

Tibullus, 87

Timone(Boiardo), 93

Tobias(Matthieu de Vendôme), 10

Tolomei, Claudio, 40

Tomitano, Bernardino, 59

Tournes, Jean de, 163

Towneley Plays, SecundaPastorum, 137, 150

Tragedy, 133, 134, 137-45

Tragicomedy, 133, 142, 148

Trattatodellaimitatione(Camillo), 50

Trimerone(Patrizzi), 184

Trionfi(Petrarch), 168

Trissino, Giovan Giorgio, 67, 158, 159, 177

Troade,La(Garnier), 141

TroilusandCriseyde(Chaucer), 15, 24, 96, 122

Turnebus, 137

Tuscan, 28, 30

Tusser, 181

UrbiumdictaMaximilianum(Caviceo), 40

Utopia(More), 226

Valla, Lorenzo, 8, 19

Varro, 58

Vauquelin de la Fresnaye, 186, 188, 189

Venatio(Adrian), 24

Vérard, Antoine, 68

Vergil, 18, 26, 30, 53, 56, 58, 63, 65, 71, 72, 79, 80, 82, 84, 86, 87, 88, 96, 98, 110, 114, 122, 123, 155, 156, 157, 160, 162, 163, 165, 166, 170, 173, 174, 177, 179, 181, 236, 238; Aeneid, 102, 104, 114, 121, 126, 127, 165, 185

Vernaculars, 5, 17, 27-38, 68-78

Verse, English discussion of, 180-84

Verse narrative, medieval, 7, 10, 91, 96

Vespasiano, 12

Vida, Marco Girolamo, 155-58, 163, 170, 172

Villon, 10, 68

Vincent of Beauvais, 10

Vinea, Gabriel, 13

Vittorino, 210

Vives, Juan Luis, 54, 210

Vopiscus, 50

Webbe, William, 180, 183

Weston, G. B., 100n

Wiat, Sir Thomas, 13, 67

Wilson, Thomas, 62

Witherspoon, A. M., 144n

Wolff, Samuel Lee, 202n

Wyatt, Sir Thomas, seeWiat, Sir Thomas

Xenophon, 93

York Plays, Nativity, 137

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