Piezo Nanomotion Technology Applied to Optical Microscopy

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PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

PiezoNanomotionTechnologyAppliedtoOptical Microscopy

Withthecontinuousdevelopmentofvarioustechnologies,opticalmicroscopybecomesmore andmoreimportant,andplaysanimportantroleinlifescience,materialscienceandotherfields. Therearemanykindsofopticalmicroscopes,suchasordinaryopticalmicroscope,fluorescence microscope,phasecontrastmicroscope,invertedmicroscope,laserconfocalscanningmicroscope, darkfieldmicroscope,polarizingmicroscopeandsoonWhenusinglightmicroscopes,the accurate,rapidandstablemovementofsamplesisveryimportantforthestudyofsamples.

Invariousopticalmicroscopysystems,withoutthesupportofnanopositioningsystem,the microscopicaccuracyoftencannotreachtherequirementsandthescanningspeedisslow Therefore,nanomotioncontrolsystemsareusedinmanymicroscopesystems.Evenifthereisno microscopeequipmentpre-equippedwithnanomotioncontrolsystem,itcanbebuiltbyitselfto addnanopositioningsystem.

Withmaturetechnologyandexperienceinpiezonanomotionandcontrolsystems,CoreMorrow hasequippedavarietyofpiezonanosamplestages,piezoobjectivescannersandpiezo controllersforvariousopticalmicroscopesystems.

ApplicationofCoreMorrowPiezoObjectiveScannerinOptical Microscopy

InvertedMicroscope

Thepicturebelowshowsaninvertedmicroscope.CoreMorrowXP-721piezoobjectivescanneris integratedbetweentheobjectivelensandtheinterfaceItprovidesafinetuningrangeof100μm forZ-directionfocusing.

ColdAtomMicroscope

Anatomicmicroscopeusesaverysharpprobeaboutthesizeofafewatomsatthetoptoscan thesurfaceoftheobjectunderobservationtocreateanimageColdatommicroscopy(coldatom

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

microscopy)isatechniqueinwhichsamplesareimagedafterbeingmomentarilyfrozenina vacuum

CoreMorrowpiezoobjectivescannerhasacryogenicvacuumversionandcanoperateina cryogenicvacuumenvironment

AutomaticCellImagingSystem

Automaticcellimagingsystemisamulti-dimensionalandhigh-resolutiondigitalmicroscopic imagingandanalysisinstrument,whichcaneasilyrealizetheimagingandbiologicalanalysisof low-densitycellsandtissuesinporousplates,includingcellcounting,unlabeledcellcounting, neuritetracking,etc.Ithasimportantapplicationsinnewdrugdevelopment,cellbiology research,histopathologicalanalysis,environmentalmonitoringandotherfields

Inthissystem,theadaptivecontinuousfocusisachievedbytheP72seriespiezoobjective scannersystem.Thepiezoobjectivescannercanachieveafocusingrangeof100μm,aresolution of25nm,andafastfocusinganimallens,thusachievingautomaticcellimaging

AutomaticMicroscope

Fullyautomaticmicroscopesareidealforindustrialscanning/inspection,metallography,laser cuttingandotherapplications.Theyarealsobasedonopticalsystemswherelightisstruckonto thesurfaceoftheobjecttobeobservedorprocessedforimagingorlaserprocessing (lithography).

TheP76piezoobjectivescannerhasalargeloadcapacityof500g,whichissuitableforfast

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy scanningandfocusingofheavydutyobjectivelenses.
objectssuchasbiologicalcells,biologicalsections,bacteriaandlivingtissuecultureThe integratedofCoreMorrowpiezoobjectivescannerinthebiologicalmicroscopecangreatly
MaterialCompositionAnalysis Materialcompositionanalysisistheanalysisofunknownsubstancesorunknowncomponents, throughtheanalysiswecandeterminethecompositionofthesampleandcomponentcontent TheP76serieshaveintegratedlarge-loadpiezoobjectivesscanner,whichcanbearthelensof heavierobjectsandprovidenano-levelfocusingaccuracy
BiologicalMicroscope Biologicalmicroscopeisapreciseopticalinstrumentusedtoobservetransparentortranslucent
improvethefocusingaccuracytonanometer

ApplicationofPiezoNanoscaleSampleTableinOpticalMicroscopy

StructuredLightTomography3DImagingTechnique

Structuredlight3Dimagingistoobtainthe3Dshapeofthesurfaceofobjectsandscenes throughnon-contact,andreconstructthesurfaceofsamplesInthereconstructionprocess, energyisradiatedtothesurfaceofthemeasuredobject,andthethree-dimensionalshapeis reconstructedbycollectingthereflectedenergy

TheimagingsystemisintegratedwiththeCoreMorrowP11piezonanopositioningstage, providingrapidnanoscalescanningforstructuraltomography.

BiologicalMicroscope

Picturedbelowisabio-microscopewithanintegratedCoreMorrowP79XYZ50Spiezosample stage,providingsamplewithanXYZtriaxial50μmprecisionscanningrange.Andthesamplecan berapidlyfocusedandscannedinmilliseconds

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy
Multi-headObjectiveMicroscopy Intheobservationprocessofsomeapplications,amicroscopicsystemwithmultipleobjectlenses willbeused.Thelow-powerlenswillbeusedfirsttofindtheobjecttobeobserved,andthenthe high-powerlenswillbeusedforhigh-precisionobservationInsomeapplications,inorderto observecellsandtissuestructuresofdifferentsizes,differentmagnificationlensesarealso

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

switched.

Amicroscopesystemwithmultipleobjectlensesandconverterswillincreasetheloadweightof thepiezonanopositioningsystemTheCoreMorrowP12Seriesonetothreedimensionalpiezo scannerwithloadbearingcapacityupto800gorhighercanbeusedformulti-lensfastnanoscale focusingTheswitchingoftheobjectlensdoesnotaffecttheZ-directionfocusingofthepiezo nano-positioningstage.

BiologicalMicroscopicImaging

P78Z200seriespiezoscanningtable,whosecoremovesintheZdirection,isappliedtothe Z-directionfocusingofbiologicalmicroscopicsystem.Tofacilitatesampleintegration,agrooveis integratedinthehollowpartoftheP78Z200sothatthesamplecanbemountedandplacedin thecentralthrough-holeposition.

FluorescenceMicroscopicImaging

Fluorescencemicroscopeisakindofmicroscopeequipmentforproductresearchbyobserving thefluorescenceofobjectsItisanimportantmeansandtoolforcarryingoutmicroscopiclife scienceresearch.Thistechnologycanbeusedtoobservethefinestructureoforganismsand dynamicallytrackthelifeactivityprocessesofdifferentscalessuchastissues,cells,nuclei, proteinsandsmallmoleculesinorganisms,andhasbeenappliedinmanydifferentfields.Suchas biologicalscience,aerospacescienceandtechnology,educationalinstitutions,etc

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Fluorescencemicroscopeusesshortwavelengthlight(excitationlight)toirradiatethesample,so thatthesampleisexcitedbyhighenergy,andproduceslongwavelengthfluorescence(emission light),whichisusedtoobserveanddistinguishthecompositionandpositionoffluorescent substancesinthesampleThroughthefluorescencemicroscopetoseethefluorescenceimage morphologicalfeaturesandfluorescencecolor,brightnessandsoontojudgeandrecordthe image

P12XYZpiezoscanningtableprovidesonetothreedimensionalnanomotion,whichcanadjust thefocusofthesampleandalsoadjustthehorizontalfieldofvision.

SeveralZ-axisandXYZPiezoSamplePlatformsDesignedby CoreMorrow Intheopticalmicroscopesystem,becauseofthedifferentstructure,thenano-motionpositioning platformwillhavedifferentstructureandparameterrequirements,CoreMorrowhasavarietyof piezonano-positioningplatformandcontrollerstandardproducts,andcustomdesignedproducts accordingtouser'sspecificapplicationenvironment Thefollowingaresomepiezosampleplatformforselectionreference P79-D1 Activeaxes:Z

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Travelrange:200μm@150V

Aperture:φ25mm×3

Closed/openloopresolution:55/2nm

Loadcapacity:1kg

P79.Z100S/K

Activeaxes:Z

Travelrange:100μm@150V

Aperture:83×65mm^2

Closed/openloopresolution:3/1nm

Loadcapacity:2kg

P79.Z200S/K

Activeaxes:Z

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Travelrange:187.5μm@150V

Aperture:83×65mm^2

Closed/openloopresolution:5/15nm

Loadcapacity:15kg

P79.Z200K-D1

Activeaxes:Z

Travelrange:200μm@150V

Aperture:86.5×128.5mm^2

Closed/openloopresolution:6/2nm

Loadcapacity:15kg

P79.XYZ50S/K-B1

Activeaxes:XYZ

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Travelrange:50μm@150V

Aperture:84×65mm^2

Closed/openloopresolution:15/05nm

Loadcapacity:05kg

P79.XYZ50S/K-B2

Activeaxes:XYZ

Travelrange:50μm@150V

Aperture:84×65mm^2

Closed/openloopresolution:1.5/0.5nm

Loadcapacity:0.5kg

P78A.Z200S/K

Activeaxes:Z

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Travelrange:200μm@150V

Aperture:φ25mm

Closed/openloopresolution:10/3nm

Loadcapacity:2kg

P78A.Z200S/K

Activeaxes:Z

Travelrange:100μm@150V

Aperture:120×70mm^2

Closed/openloopresolution:3/1nm

Loadcapacity:1kg

P78A.Z200/300S/K

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Activeaxes:Z

Travelrange:1875μmor2625μm@150V

Aperture:64×64mm^2

Closed/openloopresolution:5/15or7/25nm

Loadcapacity:1or0.5kg

P17.XY200S/K

Activeaxes:XY

Travelrange:1875μm@150V

Aperture:60×60mm^2

Closed/openloopresolution:5/1.5nm

Loadcapacity:1kg

P15.XYZ100S/K

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Activeaxes:XYZ

Travelrange:120μm@150V

Aperture:60×60mm^2

Closed/openloopresolution:35/1nm

Loadcapacity:1kg

P15.XYZ300S/K

Activeaxes:XYZ

Travelrange:300μm@150V

Aperture:66×66mm^2

Closed/openloopresolution:8/2.5nm

Loadcapacity:05kg

P15.XY100S/K-C1

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Activeaxes:XY

Travelrange:100μm@150V

Aperture:66×66mm^2

Closed/openloopresolution:35/1nm

Loadcapacity:6kg

P15.XYZ300S/K-C2

Activeaxes:XYZ

Travelrange:310μm@150V

Aperture:66×66mm^2

Closed/openloopresolution:10/5nm

Loadcapacity:5kg

P15.XY100S/K-B1

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Activeaxes:XY

Travelrange:100μm@150V

Aperture:55×65mm^2

Closed/openloopresolution:3/1nm

Loadcapacity:0.5kg

XD781

Activeaxes:Z

Travelrange:100μm@150V

Aperture:191.2×140.4mm^2

Closed/openloopresolution:3/1nm

Loadcapacity:1kg

P73.Z200S/K

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Activeaxes:Z

Travelrange:200μm@150V

Aperture:φ15~22mm

Closed/openloopresolution:55/2nm

Loadcapacity:0.2kg

P73.Z1000S/K

Activeaxes:Z

Travelrange:1000μm@150V

Aperture:φ15~22mm

Closed/openloopresolution:27/8nm

Loadcapacity:02kg

P76.Z200S/K

PiezoNanomotionTechnologyAppliedtoOpticalMicroscopy

Activeaxes:Z

Travelrange:200μm@150V

Aperture:φ27mm

Closed/openloopresolution:55/2nm

Loadcapacity:0.5kg

YouarewelcomedtocontactCoreMorrowformoredetailedtechnicalparametersandsolutions!

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