Program QBP 12_5_2025. pdf

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Quantitative Biology and Physiology, Translational Research in Biomaterials, Synthetic Biology & Biotechnology, Biological Feedback Control

GRADUATE RESEARCH SYMPOSIUM

Prospects for Semantic Mapping and Decoding with Optical Brain Imaging

Friday, December 5, 2025

RKC-101 (Eichenbaum Colloquium Room) 610 Commonwealth Avenue

CILSE - Kilachand Center for Integrated Life Sciences & Engineering

Prospects for Semantic Mapping and Decoding with Optical Brain Imaging

Joe P. Culver, PhD

Director, Biophotonics Research Center

Sherwood Moore Professor of Radiology Director, Imaging Sciences Pathway Co-Director, Imaging Sciences Doctoral Program

Washington University School of Medicine

Joseph P. Culver, PhD, is the Sherwood Moore Professor of Radiology for Mallinckrodt Institute of Radiology (MIR) at Washington University School of Medicine in St. Louis. In 2022, he was named director of the Biophotonics Research Center, which harnesses the power of light to develop methods for understanding, diagnosing and treating human diseases. He also serves as co-director of Washington University’s Imaging Sciences Pathway and its Imaging Sciences PhD program. Culver’s work has been at the leading edge of functional and molecular biological imaging, particularly in leveraging noninvasive optical measurements and advancing diffuse optical tomography (DOT) technology. He received his doctorate degree and completed biomedical optics postdoctoral training from the University of Pennsylvania.

Interdisciplinary Training Programs

Quantitative Biology and Physiology Training Program

The QBP program (QBP) is for PhD students with an interest in studying biological phenomena at all length scales using a combination of computational and experimental techniques. Supported by the National Institute of General Medical Sciences (NIGMS), a large fraction of the BME faculty, as well as faculty from other departments, are included among the advisors for this program. Trainees follow a specialized curriculum and are involved in a number of enriching activities, including journal clubs and retreats.

Translational Research in Biomaterials Training Program

To improve prospects for biomaterials solutions for tissue engineering and drug delivery, the National Institutes of Health (NIH) awarded a five-year training grant to the Biomedical Engineering Department in its nascent Translational Research in Biomaterials program (TRB). Conceived in 2006 in response to student interest, the TRB program seeks not only to train PhD students in scientific aspects of biomaterials, but also to provide them with a solid understanding of clinical trials, commercialization strategies and other concepts needed to effectively transition research ideas from the laboratory to the clinic.

Synthetic Biology & Biotechnology

The goals of the Synthetic Biology and Biotechnology (SB2) Predoctoral Training Program at Boston University are to provide a unique, field-defining, and interdisciplinary training environment in synthetic biology, directly in the heart of Boston, that enables trainees to: 1) predictively engineer complex biological systems through laboratory research and a holistic curriculum, 2) learn how to develop and translate breakthrough biotechnologies that can drive new inventions, products and therapies and 3) develop the professional and operational skills of team science, interdisciplinary thinking, and communication that are so crucial for success across the full array of careers in biotechnology and biomedical science.

Biological Feedback Control

BU’s newest graduate training program, Biological Feedback Control (BFC), is funded by the National Science Foundation. This exciting new program will form an interdisciplinary community of students and faculty that combines the study of the engineering principles of feedback control with investigations on how biological systems self-regulate, adapt, heal, and evolve. This program is open to all PhD students in engineering, natural sciences, physical sciences, health sciences, and data science.

22nd Annual

BME QBP, TRB, SB2, BFC Research Symposium

Friday, December 5, 2025

Student Emcees: Aedan Brown; Michael Wallace

KEYNOTE PRESENTATION

8:30 - 9:00 Registration/Breakfast CILSE Lobby

9:00 - 9:20 Symposium Welcome Remarks CILSE 101

Shannon Stott, Ph.D., BME Chair

Darren Roblyer, Ph.D., BME Faculty

Kate Herrema & Maya Bartels, QBP Co-hosts

9:20-10:20 Student Speakers CILSE 101

Aarohi Mehendale

Dev Raj Mehrotra

James Robson

Aalanna Farrell

10:20-10:50 Coffee Break CILSE Lobby

10:50-11:50 Student Speakers CILSE 101

Maryam Dashtiahangar

Zoe Garman

Audrey Van Heest

Jordan Smiley

12:00-1:00 KEYNOTE PRESENTATION

Joe Culver, PhD

Prospects for Semantic Mapping and Decoding with Optical Brain Imaging

1:00-2:30 Student Poster Session and Lunch Reception CILSE 106B/CILSE Rear Lobby

CILSE 101

Student Speakers

9:20-9:30

Aarohi Mehendale

Spatial Frequency Domain Imaging (SFDI) for assessment of skin involvement in Scleroderma

QBP Training Grant Roblyer Lab

9:35-9:45

Dev Raj Mehrotra

Non-destructive Longitudinal Raman Spectroscopic Monitoring of Osteoarthritis

Treatment Progression

QBP Training Grant Albro Lab

9:50-10:00

James Robson

Deciphering Sequence-to-Function Frameworks of Programmable RNA Sensors

SB2 Training Grant Green Lab

10:05-10:15

Aalanna Farrell

Investigating mechanisms of vascular toxicity by tyrosine kinase inhibitors in cancer treatment

TRB Training Grant Chen Lab

10:55-11:05

Maryam Dashtiahangar

High-throughput assessment of cooperative cofactor recruitment to composite DNA elements

SB2 Training Grant Siggers Lab

11:10-11:20

Zoe Garman

Investigating the role of relaxin-2 in uterine fibroids

TRB Training Grant Grinstaff Lab

11:25-11:35

Audrey Van Heest

Engineering Tumor Microenvironment-Responsive Biosensors for Precision Oncology

SB2 Training Grant Hao Lab

11:40-11:50

Jordan Smiley

Enhancing Vaccine-Induced Immunity with Self-Amplifying RNA

TRB Training Grant Grinstaff Lab

CILSE 106B

James Roberts

AI Agents for Biological Design Tools

QBP Training Grant Densmore Lab

Aedan Brown

Evolutionary simulations of metabolism reveal role of constant selective pressure

QBP Training Grant Cleary Lab

Samuel Zhou

Dopamine loss alters striatal cholinergic interneuron intracellular dynamics and movement encoding QBP Training Grant Han Lab

Emily Davis

FAK as a central mediator of provisional matrix assembly during stromal repair

TRB Training Grant Chen Lab

Sophie Zic

Building a custom system to perform sequential spatially resolved transcriptomic experiments

TRB Training Grant Cleary Lab

Christopher Lu

Implementing Base Editing to Correct a Pathogenic Variant of Wolfram Syndrome for Preventing Neurodegeneration

TRB Training Grant Banskota Lab

Rockwell Tang

Neurogenic low frequency blood flow oscillations and microcirculatory perfusion associated with stroke recovery

QBP Training Grant Boas Lab

Ezra Cho

Modulating Antigen Processing through Nanoporous Cages to Bias Adaptive Immunity.

TRB Training Grant Teplensky Lab

Siyi Zheng

Harnessing DNA-based vaccines to generate lung-resident immunity

SB2 Training Grant Teplensky Lab

Poster Session

Boston

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