ARCS-ai Life Sciences Proposal

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Advanced Research in Computational Sciences & Artificial Intelligence

Project Budget & Outline

Start small, and build towards regional & international prominence

Budget for 2025-26

Total support request for the Life Sciences program

Budget for 2025: $110,000

Budget for 2026: $290,000

An additional $350,000 has already been secured for the AI and Robotics programs.

Key Deliverables for 2025-26

Teaching/Training

Curriculum

❖ Delivering 8 courses to undergraduate and graduate students in Armenia in strategic areas of the life sciences: Clinical Immunology, Histology and Histopathology, Bioinformatics.

20 scholars from abroad teaching classes and engaging in collaborative research.

Training of local teaching assistants.

International

Summer School

Four week-long international summer school on Bioinformatics

❖ 3 visiting lecturers and 13 local scholars engaged.

❖ 100+ attendees from centers of excellence from around the world and Armenia

❖ Interfacing with local industry and academic institutions

Research Component

Group research projects between international participants and local researchers during the Summer school.

Hosting three principal investigators in 2026 to engage them in teaching, scientific discussions, and the development of new collaborations.

Engagement with a group of 31 ASOF scholars from top universities and research centers in the world to seed future collaborations.

Longer Term Goals

As Determined by the Council on an Ongoing Basis

Armenia has the potential to become a regional powerhouse in certain areas of science and technology that can provide for its security and wealth.

Key to achieving this is to make use of the extensive network of professional Armenians at universities and research centers around the world.

Key Directions in the Sciences & Technology for Armenia

and training. Engineering

These directions require relatively modest resources for infrastructure, but a highly educated and skilled workforce that is internationally networked with centers of excellence around the world.

The strategy is to start with local capacity building

ARCS.ai Governance

Governance Model & Operations

ASOF

Appoints

ASOF Council Appoints

ASOF Advisory Groups Advises

❖ Teaching & training programs

❖ Research programs

❖ Grant writing

❖ Seminars & Workshops

❖ Visitor program

❖ Tech transfer office Board

Educational & Research Institutions

Financial Partners and Patrons

Project/Industry Partners

The ARCS.ai Council, 2025-26

Appointed by the ASOF Executive Board

Armen Aghajanyan

FAIR (Meta)

Deep Learning, Large Language Models, NLP

Artur Alaverdyan

Co-Founder, Member of Board, Foundation for Armenian Science and Technology

Applied Physics, Entrepreneurship, High-Tech

Armen Askijian

Chief Technology Officer, Airbus U.S. Space and Defense

Aerospace Engineering, Space and Satellites, Mechanical Engineering

Diane Barber (chair)

Professor, Department of Cell and Tissue Biology, University of California San Francisco

Cell biology

Justin Du Bois

Henry Dreyfus Professor of Chemistry, Professor of Chemical and Systems Biology, by courtesy, Stanford University

Chemical Biology, Chemistry

Naira Hovakimyan

Professor, Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign

Control Theory, Optimization

Adam Kablanian

High-Tech Executive, Entrepreneur, and Investor Founder of Alexandrea Winery

Electrical Engineering, High-Tech

Ann Karagozian

Distinguished Professor, Department of Mechanical and Aerospace

Engineering, University of California, Los Angeles

Combustion, Fluid Mechanics, Propulsion

Council on Sciences & Technology

A Committee of the Armenian Society of Fellows

Sarkis Mazmanian

Luis and Nelly Soux Professor of Microbiology, California Institute of Technology

Microbiology, Neuroscience

Alexandre Persat

Global Health Institute and Institute for Bioengineering, Ecole

Polytechnique Fédérale de Lausanne (EPFL)

Biology, Biophysics, Microbiology

Ardem Patapoutian (Nobel Laureate)

Professor, Department of Neuroscience, The Scripps Research Institute Biology

Neuroscience

Vahe Petrosian

Professor of Physics and Applied Physics Departments, Chair of Astronomy Program, Stanford University

Astrophysics, Cosmology

Dork Sahagian

Professor, Department of Earth and Environmental Sciences, and the Environmental Initiative, Lehigh University

Climate Change, Geophysics, Science and Society, Volcanology

Armen Zakarian

Vice Provost for Research, Professor and Chair, Department of Industrial and Manufacturing Systems Engineering, University of Michigan Dearborn

Data Analytics, Digital Manufacturing, Systems Engineering

Representatives from the Armenian Government (Ex-Of fi cio)

Ministry of ESCS

Ministry of HTI

Parliament of the Republic of Armenia

The ARCS.ai Armenia Board 2025-26

Appointed by the ARCS.ai Council

Haig Alexander Eskandarian

Department of Systems Biology, Harvard Medical School Biology, Medicine, Microbiology

Aram Galstyan

University of Southern California, Amazon Artificial Intelligence, Computer Science

Ivan Aprahamian Professor, Chair of the Chemistry Department, Dartmouth College Organic Chemistry, Adaptive Materials

Oshin Peroomian (Treasurer)

CTO Metacomp Technologies, Inc. and Adjunct lecturer at AUA

Computational Fluid Dynamics, Computational Multi-Physics

Nora Ayanian (chair)

Professor, Brown University

Computer Engineering, Computer Science, Robotics

Karen Eguiazarian (Vice-Chair)

Professor in Signal processing, Tampere University, Finland, and CEO of Noiseless Imaging Ltd

Computational imaging & optics

Vatche Sahakian (Secretary)

Burton Bettingen Professor in Theoretical Physics at Harvey Mudd College

Key Partners

Research

Funding

Institutions

Execution Team 2025-26

Teaching, Research, & Workshop

Instructors from Outside Armenia

Prof. Raffi Aroian, Program in Molecular Medicine, University of Massachusetts Chan Medical School, US.

Dr. Karl Balabanian, INSERM Research Director, Deputy Director of the Saint-Louis Research Institute, Saint-Louis Hospital, France.

Prof. Ronald Balassanian, Anatomic Pathology Residency Director, Pathology Division, University of California San Francisco, US.

Dr. Nelli Bejanyan, Program Leader, Blood and Marrow Transplant and Cellular Immunotherapy, Moffitt Cancer Center, US.

Dr. Haig Alexander Eskandarian

Prof. Franck Galland, Aix-Marseille Université, Centre d’Immunologie de Marseille-Luminy (CIML), INSERM, France

Dr. Sylvain Garciaz, Chef de clinique-Assistant des Hôpitaux, Institut PaoliCalmettes (IPC), CRCM, Aix-Marseille Université, CNRS, INSERM, France

Prof. Sumeet Gujral, Department of Pathology, Tata Memorial Center, Mumbai, India

Prof. Robert Hasserjian, Director, Hematopathology Fellowship Program, Pathology Service, Harvard Medical School, US

Prof. Bana Jabri, Department of Medicine at the University of Chicago, US.

Prof. Philippe Karoyan, Head of Biomolecules laboratory, Sorbonne Université, Ecole normale supérieure, PSL, CNRS, AP-HP, France.

Dr. Aleksandr Lazaryan, Blood and Marrow Transplant and Cellular Immunotherapy, Moffitt Cancer Center, US.

Dr. Anna Martirosyan, Head of Scientific Department of Santé Arménie NGO, France.

Prof. Sarkis Mazmanian, Luis and Nelly Soux Professor of Microbiology, California Institute of Technology, US.

Prof. Arsène Mekinian, President of the French Group « MINHEMON », President of Santé Arménie NGO, Saint-Antoine Hospital, France.

Dr. Haig Minassian, Bayshore Medical Center at Hackensack Meridian Health, Holmdel, US.

Dr. Emilie Narni-Mancinelli, CRHC, INSERM, Centre d’Immunologie de Marseille-Luminy (CIML), France

Dr. Rosalynn Nazarian, Associate Pathologist, Massachusetts General Hospital, Associate Professor of Pathology, Harvard Medical School, US

Dr. Jihane Pakradouni, Director of Clinical Research and Innovation at the Institut Paoli-Calmettes, France.

Prof. Alexandre Persat, Global Health Institute and Institute for Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Switzerland.

Dr. Carole Siret, Expert in Light Sheet Microscopy, Centre d’Immunologie de Marseille-Luminy (CIML), Aix-Marseille Université, France.

Dr. Aurélie Tchoghandjian, Head of the GlioME team, Institute of Neurophysiopathology, CNRS, France.

Local Instructors

Dr. Anna Karapetyan, Head of Department, Head of chair of Human and Animal Physiology, Faculty of Biology, Yerevan State University, Armenia

Dr. Lilit Nersisyan, Director, Lab Leader, Armenian Bioinformatics Institute

Dr. Alvard Poghosyan, Head of the Histopathology Diagnostic Laboratory at Yeolyan hematology and oncology center, Yerevan, Armenia

Project Leads

Dr. Anna Martirosyan Head of Scientific Department of Santé Arménie NGO

Dr. Lilit Nersisyan Director, Lab Leader, Armenian Bioinformatics Institute

Curricular Program

Clinical Immunology

14 weeks including hands-on training for 2 weeks

1. General Immunology

2. Immunopathology

3. Biotherapies

Histology and Histopathology

14 weeks including hands-on training for 2 weeks

1. Overview of the IHC technique

2. Introduction to Digital Pathology

3. Hematopathology

4. Breast and Skin pathology

Master Class

4 days

Students

International Summer School in Genome Bioinformatics

Bioinformatics Algorithms

Functional Genomics

Group projects

1. Machine Learning-Based Identification of Bacterial Biomarkers for Disease Classification

2. Discovery of Telomeric Biomarkers for Cancer Detection in Cell-Free DNA

Hands-on Course on Host-Pathogen Interactions 27 Instructors 9 Courses

1. Scientific Writing

2. Leadership in Science

3. Career Development

3. Genomic Characterization of Population Structure in Caucasian Grape Varieties Using Whole-Genome Sequencing

4. Dissecting Lung Cancer Heterogeneity via Single-Cell Transcriptomic Profiling

Research Operation

Teaching with hands-on training

❖ The Binder Lab, focusing on cancer and plant genomics

❖ The Nersisyan Lab, investigating host-microbiome interactions with a focus on aging and microbiome dynamics

❖ The Bioinformatics Core Facility, providing genomics data analysis and sequencing services in collaboration with the Institute of Molecular Biology, NAS RA

Bioinformatics collaborations

The project plans to host three principal investigators (PIs) in 2026 to engage them in teaching, scientific discussions, and the development of new collaborations. These visits will also serve as an opportunity to apply for international grants and receive mentorship. The PI’s will be selected based on expertise in research in cancer multi-omics, the microbiome, and liquid biopsies.

Each PI will spend up to four weeks in Armenia, working closely with the ABI team, mentoring students, and interacting with the broader life science community. During their visit, the PI’s will also deliver lectures as part of the OMICSS-26 Summer School in Genome Bioinformatics. At the end of their stay, following the school’s bootcamp, we will organize a two-day conference showcasing current research from the visiting PI’s, ABI researchers, and other scientists in the field.

research operations in partnership with YerevaNN meant to interface with other disciplines like the Life Sciences, Robotics, and Biomedical Imaging. This program is coordinated with the recently purchased $7 million Nvidia supercomputer, and the recently launched $500 million Firebird initiative.

The Armenian Society of Fellows

Société Savante Arménienne Bibliothèque Nubar, 11 Sq. Alboni, 75016 Paris, France

The Markarian chain of galaxies

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ARCS-ai Life Sciences Proposal by ASOF Administrator - Issuu