Buy Dutasteride Powder Online Uses, Dosage, Side effects(6)

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Buy Dutasteride Powder Online: Uses, Dosage, Side effects(6)

11.Dutasteride powder vs Finasteride, Which Raw Material Powder Is Better? The importance of dual 5a-reductase inhibition in the treatment of male pattern hair loss. Olsen E. et. al. SUMMARY In the study, 416 men with male pattern hair loss (MPHL) ages 21 to 45 years old, were randomized to receive Dutasteride raw powder 0.05, 0.1, 0.5 or 2.5 mg, finasteride 5 mg, or placebo daily for 24 weeks. The results of the study showed that Dutasteride powder increased hair counts in a dose-dependent fashion and Dutasteride raw powder 2.5 mg was superior to finasteride 5mg at 12 and 24 weeks. Although testosterone is the major circulating androgen, to be maximally active in scalp hair follicles it must first be converted to dihydrotestosterone (DHT) by the enzyme 5?-reductase. The importance of DHT as a causative factor in male pattern hair loss is shown by the absence of this MPHL in men with a congenital deficiency of the type 2 5?-reductase enzyme. A type 1 5?-reductase, which also metabolizes testosterone to DHT, differs in its location and amount in different tissues. In the skin, type 1 5?-reductase is the principal isoenzyme in sebaceous and sweat glands. There is no recognized genetic deficiency of type 1 5?-reductase in humans to assess its role in MPHL. Dutasteride powder (Avodart) inhibits both type 1 and type 2 5?-reductase and is approved at the 0.5-mg dose for treatment of symptomatic benign prostatic hyperplasia (BPH). It is about 3 times as potent as finasteride at inhibiting type 2 5?-reductase and more than 100 times as potent at inhibiting the type 1 5?-reductase enzyme. 1

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