Combination of Gaming and Sensor Glove to Monitor Motor Function in Children Periodic motor function assessment is critical for implementing correct rehabilitation interventions, but access to specialized care is limited for pediatric patients living in rural areas. Our objective is to develop low-cost, accurate system to monitor upper extremity motor function. We have recently developed a computer-based application that uses a pointing task with multiple levels of difficulty to test motor function, and have validated this video game as a measure of dexterity in adult and pediatric subjects. We are currently developing a prototype of a sensor glove that measures angles of movement. We plan to use the game-and-glove combination for regular school- or home-based evaluation and self-evaluation of treatment efficacy that will facilitate the development of appropriate rehabilitation interventions. Paola Pergami Pediatrics 304-293-7331 ppergami@hsc.wvu.edu
Clinical Pharmacology of Anticancer Drugs   
New drug development focusing on design of late preclinical and early human phases. Clinical pharmacology of anticancer drugs. Investigations evaluating mechanisms of inter-individual variability in drug disposition.
William Petros MBRCC/Basic Pharmaceutical Sciences 304-293-0495 wpetros@hsc.wvu.edu
Nanotechnology and Anticancer Therapeutics Research focus is in understanding how cancer cells become resistant to death and how they gain competitive advantages over normal cells. Research also involves molecular mechanisms of nanomaterial-induced carcinogenesis and development of anticancer therapeutics. Yon Rojanasakul Pharmaceutical Sciences 304-293-1476 yrojan@hsc.wvu.edu
21