Global Innovation in Wound Care Summit Series What Do I Need to Know About Skin Substitutes? Moderator Miss Negin Shamsian Consultant Plastic and Reconstructive Surgeon (Locum) London, United Kingdom
requirements. Surgery and secondary healing is good, when a combined approach can occur, but the key question is when to use what. Dr N. Shamsian precedes to ask, ‘What is the most common type of wound you see?’, to which Devine responds that it is mostly chronic wounds; venous
Introduction
ulcers, lower extremity wounds, and sometimes
D
surgery from previous cancer treatment. The use r N. Shamsian is joined by North American
of skin substitution is vital as it can prevent further
expert Dr J. Lantis (Professor and Chief in
arduous surgical management and gives the clinician
Surgery), Associate Professor M. Wagstaff
options for preservation and treatment.
(Head of Plastics and Reconstructive Unit, Australia) and Dr M. Devine from Arizona (Plastics and
“How has microsurgical transfer to skin substitutes
Reconstructive Surgeon).
changed over the last 2 decades?”
Global expert
Due to the variety of options available for skin substitution, there is a lesser need for surgical
Dr Michael N. Desvigne
transfer, but rather more additional scaffolding with
Board-Certified Plastic Surgeon, General Surgeon, Hyperbaric physician, Wound Care Clinician
skin substitutes and the advantage of synergistic
Scottsdale AZ, United States
of experience, or expertise, is within the field of
substitution. Devine explains that his primary area placental-type products.
Supported by
The Use of Aseptically Processed Placental Allograft
Processing the material matters as you can achieve
and Meshed Reticular Acellular Dermal Matrix in
the same sterility as terminally sterilized tissue
Soft Tissue Reconstruction
which preserves tissue structure, matrix proteins and signaling cues. This provides a safe, quality
62
Dr M. Devine hosts the next segment of wound
tissue that is most like native autograft (human skin).
management as a Plastics and Reconstructive
Terminal sterilization alters tissue properties of the
surgeon based in Arizona. Devine notes that there are
native tissue by denaturing the structure and matrix
a lot of options for skin substitutes, and it depends
proteins, with a compromised binding site for cell
on the goal and customized approach of the patients’
attachment and signaling functions.
Wound Masterclass - Vol 2 - December 2023
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