SARMsPharm Therapy Shows Large Muscle Gains

SARMsPharm Therapy Shows Large Muscle Gains The way to big, strong muscles is long and requires hard work in a gym. But researchers may have found a shortcut where the muscles grow by themselves. Scientists have actually succeeded, by way of gene therapy, to improve the lean body mass and the strength of macaque monkeys. The experiment was simple enough, the researchers just injected the gene follistatin (FS344) directly into the monkeys right thigh muscles.

It's been shown that follistatin can block myostatin, a molecule that down-regulates musclegrowth, but strengthens tendons. Eight weeks after the injection the circumference of the monkeys right thigh muscles, had normally risen 15 percent in contrast to the left thigh. A study done on two of the monkeys indicated that musclestrength in the proper leg was increased by respectively 12 and 36 per cent compared to the untreated leg!

The Follistatin is injected by means of a viral vector, that is a Adeno Associated Virus used as a Ligandrol for sale transport for the drug that is injected.

It is just a common method called Gene Therapy, and has been found in humans with other drugs.

The study on the monkeys showed no negative side effects.

This therapy has been developed for use within patients with severe muscle dystrophy and other muscle wasting disorders.

Clinical trials on humans are due to start in 2011 and Nationwide Childrens Hospital in Ohio has recently gained funding for the study. There are numerous studies and clinical trials either underway or planned for treatment of muscle wasting disorders, among a few of the more interesting substances are Follistatin being an antagonist to Myostatin, Ostarine which is a SARM(Selective Androgen Receptor Modulator) and happens to be in Human clinical trials by GTx Inc. and also another SARM beneath the codename BMS-564,929 that is being produced by Bristol-Myers Squibb.

The possibility of these substances to be abused by athletes has prompted the World Anti-Doping Agency to have a ban on SARMs since 2008.

Sofar only the substance called "SARMs S4" (Andarine) has caused it to be to industry, and is being used by a small quantity of pro and amateur bodybuilders, it's anabolic effects are reported to be moderate and it's been reported to own some temporary negative effects, among which decreased night vision could be the more prominent.

The future of drugs developed for muscle wasting diseases are sure to be of interest for athletes and others wanting to gain the additional advantage.

The next 5-10 years will dsicover various substances emerge and some could be good replacements for Anabolic steroids.

These drugs will be available through the black market for pro and amateur athletes alike, with unprecedented anabolic effects and close to no negative side effects.