Antioxidants activity The reduction potential of ascorbate is such that it readily
donates electrons/hydrogen ions to regenerate other antioxidants, such as vitamin E, glutathione, and uric acid, and to reduce numerous reactive oxygen (ROS) and nitrogen species (RNS). Ascorbic acid interact with oxidants in the aqueous phase (blood or intracellular) before they initiate damage in nucleus, cell lipids. Ascorbate = thiols > bilirubin > uric acid > vitamin E