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PHARMACY

Target your pain.

ABOUT TOPICAL GELS Undesirable side effects, such as increased sensitivity caused by nonsteroidal anti-inflammatory drugs (NSAIDs), can be avoided with the use of topical gels. Following are proven examples of such use: • Topical ketamine can reduce the effects of substance P, a neurotransmitter implicated in pain syndromes; • Topical administration of clonidine helps alleviate a condition (sympathetic afferent activation) causing increased heart rate and blood pressure, among other things; • Topical opioids can prevent pain at the site of an injury by binding receptors in the brain, spinal cord and digestive tract. Binding receptors reduces the release of the calcitonin gene- related peptide (CGRP) and substance P from nerves, where the pain mechanism originates; • Topical application of pentoxifylline has effectively provided relief for some neuropathic conditions; • Topical tricyclic antidepressants, such as doxepin and amitriptyline, have been effective in reducing neuropathic pain.

Location Bristol, TN 310 Bluff City Highway

CONTACT (423) 764-4136 (800) 263-8890

With their potential to provide pain relief without adverse side effects, topical NSAIDs are widely used to treat acute musculoskeletal conditions, often caused by strains, sprains or sports/overuse-type injuries. Topical creams also can be effective in treating osteoarthritis. Researchers at the University of Connecticut School of Medicine examined the effect of a topical cream in treating 40 patients diagnosed with osteoarthritis of one or both knees. Treatment consisted of cetylated fatty acids (CFA). After treatment, significant improvements were noted for knee range of motion, ability to walk up and down stairs, walking and sitting down, ability to rise from sitting, and unilateral balance. The professionals at Anderson Compounding Pharmacy have received advanced training and use specialized equipment, FDAcertified chemicals and cosmetically-appealing bases to customize medications that address the individual needs of each patient. We work together with physicians and other healthcare practitioners to solve medication problems.

To learn more about Anderson Compunding, please visit

www.andersoncompunding.com

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