We celebrate the 50th issue of ESE’s membership magazine (page 16). Our President Martin Reincke explores the huge range of educational activities for 2023, and read about the ESE Awards (page 4) and the EYES Observership Programmes on page 6. Boris Mankovsky, President of the Ukrainian Diabetology Association provides an insight on current events in Ukraine (page 12). On page 11, read about ESE’s close collaboration with the European Association for the Study of Obesity, to bring about change in the management of the disease amongst healthcare providers and policymakers. Maria Chiara Zatelli, ESE’s Secretary tells us about her career on page 7. On pages 14 & 15, we gain insights into two topical areas: issues related to transgender endocrinology, and the late effects of cancer therapy, from ESE journals. And sadly, it will soon be time to say ‘Goodbye’ to our Editor Justo Castano, who has contributed so much to this magazine with his passion and experience! Could you be his successor?