20947 - Velico - VeliPod Brochure_AW Final

Production Capacity 1 Operator 1 Shift 7,500 units PA 1 Operator 2 Shifts 15,000 units PA External Dimensions 20ft x 8ft /6.1m x 2.4m Internal Dimensions 18ft x 7ft /5.5m x 2.1m Our COMPACT model is perfect for organizations with established storage and unboxing facilities, looking to seamlessly integrate the module with existing blood center component laboratories.

Production Capacity 1 Operator 1 Shift 7,500 units PA 1 Operator 2 Shifts 15,000 units PA External Dimensions 20ft x 16ft /6.1m x 4.9m Internal Dimensions 18ft x 15ft /5.5m x 4.6m Our MAX model provides double the space with a double anteroom for unboxing, a separate changing area and clean storage vestibule. This is ideal for an organization that requires a full stand alone production facility.

Production Capacity 1 Operator 1 Shift 15,000 units PA 1 Operator 2 Shifts 30,000 units PA External Dimensions 20ft x 24ft /6.1m x 7.3m Internal Dimensions 18ft x 22ft /5.5m x 6.7m Our ULTRA model provides 50% more space.

A large anteroom for unboxing, a separate changing area, a clean storage vestibule, and double the production capacity of our COMPACT or MAX models. This is the perfect solution for an organization that requires a high capacity stand alone production facility.

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Based on a standard shipping container, our veliPod range of Modular Spray Dried Plasma Labs offer potential solutions for rapid spray dried plasma production capability.

There are three standard layouts available, which can be used as designed or customized to meet your specific needs.

Each veliPod requires a separate clean, dry air system, which is also available as a containerized solution (AIRCUBE), to support Spray Dried Plasma production. veliPods can be customized to meet specific requirements, including additional building codes, compliance standards, accessibility needs, and certifications mandated by regional planning authorities, industry regulators, or institutional guidelines.

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Introducing FrontlineODP™ Preventable death from hemorrhage following trauma is a global concern which has been targeted by trauma surgeons, emergency medical providers, mass casualty planners, the military and national governments as a top priority. Velico is proud to be developing the FrontlineODP™ Spray Dried Plasma System in support of this call to action.

FrontlineODP™ is a spray dried plasma unit designed for rapid rehydration, intended to support the management of traumatic hemorrhage in situations where conventional plasma is unavailable or impractical. This includes pre-hospital transfusions, rural and austere healthcare settings, and military applications.

This is our innovative solution…

FrontlineODPTM Spray Dried Plasma System

Liquid Plasma

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VeliDryer

VeliSealer

FrontlineODPTM (On Demand Plasma)

Spray Dried Plasma Ready for rehydration

The FrontlineODP™ Spray Dried Plasma System is being designed for easy integration in blood center component laboratories.

Decentralized production by blood centers will aim to take advantage of blood component manufacturing expertise and product supply chains, from established volunteer blood donor bases to end user distribution including emergency logistics channels.

Watch a video on our production process:

Decentralized production sets the stage for local spray dried plasma self-suffciency and national emergency preparedness including civilian, government and military collaboration for strategic stockpiles and readiness for major mass casualty events.

VeliPod

Engineered for remote locations

Customized to meet specific needs

Supports highcapacity production

FrontlineODPTM System

Decentralized manufacturing

Integrates into blood bank labs

Designed for ease of use and operation

FrontlineODPTM (On Demand Plasma)

Rehydrates in 2.5 minutes

Comparable Factor Activity

Lightweight PVC Bag

Optimized for Extended Shelf Life

Stability Targets Room Temperature

Refrigerated

1 Year

2 Years

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Why is it needed?

30-40 percent of deaths from bleeding are considered preventable. In the United States alone preventable death from bleeding takes over 30,000 lives per year with over 100,000 more estimated throughout the rest of the world †.

A spray dried plasma solution has the potential to transform blood product distribution within the EMT community. Its extended shelf life could enable emergency vehicles to carry plasma for longer periods compared to whole blood or other alternatives, reducing the need for frequent replenishment.

Additionally, since spray dried plasma is designed for ambient storage, it offers a life-saving advantage in situations where emergency vehicles lack proper refrigeration but can maintain controlled ambient temperature conditions. This innovation could significantly enhance access to plasma in pre-hospital and remote emergency settings. †

Cannon JW. Hemorrhagic shock. N Engl J Med. 2018 Jan 25;378(4):370-9

VeliDryer

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Our Model Velico’s model is based on partnerships with regional blood centers which collect, test and manufacture life saving blood components every day. The FrontlineODP™ Spray Dried Plasma System is being designed for straightforward integration into existing blood component manufacturing centers without the need for specialized processing environments (e.g. clean rooms).

FrontlineODPTM Model Military Usage

Velico Medical Inc.

Military Bases/ Local Blood Centers

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Manufactures Systems / Consumables Sells Systems / Consumables to military Bases

Produces FrontlineODPTM Provides to Military Medical / Service Members

FrontlineODPTM (On Demand Plasma) Intended Use FrontlineODPTM has the potential to revolutionize emergency and prehospital care by: Expanding plasma accessibility for ground and air EMS teams Enhancing availability in rural and underserved areas

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Providing battlefield-ready plasma solutions for military use Strengthening mass casualty preparedness with regional stockpiles

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Rehydration

Transfusion

The FrontlineODP™ unit can be easily rehydrated in two and a half minutes with 200ml of sterile water (SWFI), making it practical in prehospital and hospital settings (i.e. rural) where fresh plasma is unavailable.

Uncontrolled hemorrhage is recognized as the leading cause of preventable death among victims of trauma. The early administration of plasma has been demonstrated to be lifesaving for many of these patients †.

Sperry JL, et al. Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock. N Engl J Med. 2018 Jul 26;379(4):315-326 †

Watch a video on our rehydration process:

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Together, we can make a real difference For more information please contact: Richard Meehan, President & CEO

Andre Cap, Chief Scientific Officer

US: +1 (978) 338 4590 EU: +353 (86) 020 9272

US: +1 (210) 410 6882

rmeehan@veli.co

acap@veli.co

US

Europe

100 Cummings Center # 436H, Beverly, MA 01915, United States +1 978 232 8370

5 Clarendon Mews, Lad Lane, Dublin 2, Ireland, D02 EE61 +353 1 2500 055

www.veli.co CAUTION: Investigational device. Limited by Federal (or US) law to investigational use. The FrontlineODP™ System is currently under investigation and has not received FDA approval for any indication. Program Funded by BARDA. Contract number #75A50121C00059