ICON 2013 PROGRAM

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Data • Debate • Re sol ut “i of the Storm” February 24-28, 2013 Westin Kierland • Scottsdale, AZ

PRELIMINARY PROGRAM

Co-Chairmen: Edward B. Diethrich, MD Zvonimir Krajcer, MD

Presented by:

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S U N d ay

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Pre-Event: Conquering Critical Limb Ischemia 7:00am - 5:30PM Program Directors: Venkatesh Ramaiah, MD and Craig Walker, MD

Session I

Conquering Critical Limb Ischemia

Welcome and Introduction The Epidemic of CLI: Where Are We and Where Are We Headed?

Session II

Current Literature, Tools and Techniques of Aortoiliac Revascularization Endovascular Treatment has Largely Replaced Surgery Surgery is Still the Gold Standard Covered Stents are Better Than Bare Metal Stents: What is the Data?

Case Discussion, Tips and Tricks

Session III

Current Literature, Tools and Techniques of CFA and Profunda Revascularization Can We Justify an Endovascular Approach to CFA/Profunda Revascularization?

This is a NO Stent Zone. So Why Are we Stenting Para Profunda Lesions?

Session IV

Current Literature, Tools and Techniques of Femoralpopliteal Revascularization and Beyond

Stenting is Still the Treatment of Choice in the SFA In Spite of Fractures and Restenosis: Data Proves It Which Stent and Why in the SFA and Popliteal Treatment of In-Stent Stenosis Drug Eluding Stents: Is This The New Frontier?

Dissecting and Atherectomy Devices: When, How, Why and Why Not to Use Them Lasers: When, How, Why and Why Not Turbohawk: Solving Some Issues, But Not All Diamondback: Options, Risks and Benefits Jetstream: Calcium, Thrombus, Plaque Case Presentation The Role of Specialty Balloons in SFA/Popliteal Treatment Drug Elusion in the SFA–Lutonix/INPACT. The Status of Studies in the USA and Abroad

Debate

Long Segment SFA Occlusions Are Best Treated Surgically vs Endovascular is Still the First Line Treatment in Long Segment SFA Occlusions

Pre-iCON Training Event:

Hands-On Vena Cava Filter Workshop Proctor Dr. John Jacobs, MD Presented by Cook Medical

February 24, 2013 Register online at: iconmeeting.org Arizona Heart Foundation Translational Research Center

Industry Luncheon Session

Overview of CTO Devices Access Techniques: Femoral, Popliteal, Brachial and Radial Closure Devices

Session V

CLI Strategies: Tools and Techniques of Limb Salvage

The Angiosome Concept Assessing the CLI Foot: ABI, TCOM, Skin Perfusion Pressure Pedal Access, Transcollateral Approach and Pedal Arch Reconstruction

Debate

Surgery Should be the First Line of Treatment for CLI vs Endovascular Should be the First Line of Therapy for CLI Case Presentation Balloon Angioplasty is Better Than Atherectomy and More Cost Effective in BTK Lesions in CLI BTK Stenting in CLI Hybrid Approach to Limb Salvage: Open Vascular Surgery Compliments Endovascular Approach

Session VI

Multidisciplinary Approach to CLI: Role of Medical Therapy, Value of Genetic Testing and Foot and Leg Salvage Preserving a Functional Foot After Limb Salvage Fixing Charcot Foot Medical Therapy: The Role of Statins, Antiplatelets, Anticoagulants and Cilostozole in CLI The Role of Thrombolysis in CLI Genetic Testing: Is There a Rational New Concepts in Wound Care: Stem Cell Therapy

Session VII

Complications and Future Therapies

Complications of Endovascular Revascularization I: How to Manage Perforation and Compartment Syndrome Complications of Endovascular Revascularization II: How to Manage Bleeding, Embolization and Thrombosis How to Manage No Reflow Bioabsorbable Stents Photopac, Laser and US Facilitated Delivery of Paclitaxel Angiogenesis and Gene Therapy Economics of it All

Grand Opening Reception: Introducing the theme of

Data • Debate • Resolution “i of the Storm” 6:30PM - 10:00PM

M o n d ay

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Session I 8:00–9:30AM Abdominal Aortic Aneurysms: EVAR - Present Data and Future Projections Endovascular Aneurysm Repair: is Reintervention in EVAR Predictable? - George Welch, MD Is Delayed Treatment in Young Patients With Small AAA and Aortic Anatomy Suitable for EVAR Still Ethical Today With the Latest Available Endoprosthesis? - Giancarlo Accarino, MD Over One-Third of Patients With Unstable AAA Sacs and/or Endotension After EVAR Have Intermittent or Posture Dependent Endoleaks: Diagnosis, Management and Outcome - James May, MD The Facts About Endoleak - Chris Zarins, MD Surveillance – “One Size Fits All” is no Longer Rational - Alan Karthikesalingam, MD Endovascular Approach to AAA Repair is not Without Serious Limitations - Daniel Clair, MD Paradigm Shift in Ruptured AAA Management; Ten Years’ Experience in a Tertiary Referral Center of Endovascular Repair vs. Open Repair - Sherif Sultan, MD The Future is all About Percutaneous - Zvonimir Krajcer, MD Discussion / Audience Questions Session II 10:00–11:30 New and Evolving EVAR Technology (Non CME Session): Companies developing endograft technology are invited to present new and evolving designs. A company or company-designated physician may make the presentation.

Luncheon Sessions Session III 1:15–2:15PM Edward B. Diethrich Vascular Surgical Society: Lessons and Experiences of Former Trainees Endovascular Therapy in Genetically Triggered Thoracic Aortic Disease - Ourania Preventza MD Bilateral Endovenous Laser Therapy: Safety and Efficacy - Clark A. Davis, MD Early and Mid-Term Results of Endovascular Treatment of Pseudoaneurysms After Remote Surgery for Aortic Coarctation - George Koullias, MD Session IV 2:15–3:45 TASC II: Why the Guidelines are not Being Followed Emphasis on Peripheral Interventions and CLI Imaging for the Angiosome - Allan Reid, MD Hybrid Modalities in the Treatment of Lower Extremity Arterial Disease: at the Edges of TASC II - Terezia Andrasi, MD Challenging Cases and Discussion Session V 4:15–6:00 Complex Peripheral Disease - What are the Best Solutions?

Experience in the use of SUPERA Stent in the Treatment of Femoral and Popliteal Lesions - Alberto Benassi, MD Treatment of In-Stent Stenoses With Covered Stents - Amir Motarjeme, MD Treatment of In-Stent Restenosis Using Laser Debulking and Drug-Eluting Balloons - Jos van den Berg, MD, PhD Extreme Interventions for Limb Salvage in Diabetic Patients - Gustavo Rubio Arguello, MD Best Approach to Giant Popliteal Aneurysms - Jacques Busquet, MD The Role of Covered Stents in Iliac and Femoral Obstructive Disease - Maria Ruffino, MD

in d us t r y L unc h e o n s y mp o siums Reach your target audience in a highly focused forum.

iCON2013 Lunch Symposiums offer a private venue to present your company’s latest technology.

Only three spots remain so reserve your space quickly!

Contact kkent@azheartfoundation.org to reserve today!

Tu e s d a y

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Session VI 8:00–10:00AM Thoracoabdominal, Pararenal, Juxtarenal and Short Neck Aneurysms: CHIMPS vs. Branched and Fenestrated Devices Follow-up Experiments of Former In-Vitro Chimney Studies - Jan Blankensteijn, MD Endovascular Treatment of Complex Aortic Aneurysms (Aortic Arch, Thoracoabdominal, Aortoiliac and Isolated Common Iliac) With the Sandwich Technique: Evaluation of a 78-Patient Single-Center Experience - Armando Lobato, MD Results of the UK Multicentre Study of Fenestrated Endovascular Aneurysm Repair - Srinivasa Vallabhaneni, MD Contemporary Outcomes in Thoracoabdominal Aortic Aneurysm Repair in Patients With Marfan Syndrome Outcomes are Outstanding and MFS Remains Best Treated by Open Repair - Joseph S. Coselli, MD Genetic Testing in Aortic Disease? Does it Matter? Modes of Failure of TEVAR in Connective Tissue Disorder Patients - James H. Black III, MD Changing Incidence of Spinal Cord Ischemia in Modern Day TEVAR - Robert J. Feezor, MD Disruptive Endovascular Technology With Multilayer Flow Modulator Stents as a Therapeutic Option in the Management of Thoracoabdominal Aortic Aneurysms - Sherif Sultan, MD Predicting the Long-Term Outcomes after TEVAR - Alan Karthikesalingam, MD Experience with the Fenestrated Repositionable Anaconda Device in AAA - Peter Bungy, MD

Session VII 10:30–12:15PM Vascular Surgery Spars With Cardiology: Facts on Carotid Stenting. Will Medical Therapy or Personalized Health Care Make These Irrelevant?

The Time to Accept Carotid Artery Stenting is Now - Chris White, MD Accepting Carotid Artery Stenting on a Wide Scale Will Only Increase The Stroke Rate - Anne L. Abbott, MD Neither the Cardiologists nor the Surgeons Have it Straight - Frank Veith, MD A Multi-Disciplined Approach is the Only Answer to the Question - Nick Hopkins, MD The Role of Carotid Artery Stenting in Urgent/Emergent Settings - Carlo Setacci, MD The Impact of Chronic Renal Insufficiency on the Outcome of Carotid Artery Stenting.

Does it Affect Patient Selection? - Ali AbuRahma, MD Stroke Risk Stratification in Patients with Asymptomatic Carotid Stenosis - Andrew Nicolaides, MD Only Centers Performing Both CEA and CAS can Tailor the Proper Technique to Each Patient - Giancarlo Accarino, MD Luncheon Sessions Session VIII 1:30–3:30 International Endovascular Forum: Bringing World Knowledge to the Forefront – We Can Learn From One Another Chairmen: Edward B. Diethrich, MD and Marvin Woodall Moderators: Jacques Busquet, MD and Donald Reid, MD Industry Panel: Anthony Semedo (Medtronic) Clinical Panel: Clifford Buckley, MD and Rodney White, MD Participants will converge from around the world to explore how inter country collaboration can expand the horizon of the endovascular field by examining the strengths and weaknesses shared by all. Members of the ISES team have traveled from continent to continent to create an atmosphere conducive to this type of forum in the backdrop of iCON2013.

Data – Debate and Resolution can create a consensus not previously appreciated and we bring our colleagues closer together regardless of their origins.

Session IX 4:00–4:30 JEVT Historic Supplement: “Behind the Iron Curtain” It is not uncommon in the history of medicine that a significant contribution was not recognized or attributed to its originator. When one appreciates the enormous impact of the Iron Curtain where an entire people became completely isolated from the rest of the world, a later recognition of a profound series of discoveries is understandable.

Such is the case with Professor Nicolas Volodos who for years living in the Ukraine, was faced with a communication barrier. For the first-time ever, the Journal of Endovascular Therapy is proud to present a supplement extolling the momentous contributions of this Ukrainian surgeon. This special issue will be distributed during the session where this historic journey is portrayed.

Contributor: Krassi Ivancev continued on next page

G O L F

C L U B

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T U e s d ay

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iCON2013 is close to shopping, food & entertainment

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Session X 4:30 – 5:30 The Evolution of Endovascular Materials and Methods Chairman: Francesco Serino, MD Time to Change - Francesco Serino, MD Fluid Dynamics I - Alan B. Lumsden, MD Fluid Dynamics II - Grayson H. Wheatley III, MD Combined Cardiac Surgery and Endovascular Repair of Abdominal Aortic Aneurysm -Srinivasa Vallabhaneni, MD Role of Pelvic Varices Sclerotherapy in Treatment of Lower Limbs Venous Insufficiency - Silvia Giuliani, MD Percutaneous Reconstruction of the Aortoiliac Bifurcation is Effective for Revascularization of a Distal Aortic Occlusion - Amit Nanavati, MD Outcome of Stenting in the Subclavian Vein for Upper Extremity Edema - Mohsen Sharifi, MD Endovascular Treatment and Stem Cell Therapy of CCSVI - Ivo Petrov, MD Pharmacogenomics for the Vascular Specialist - Karthikeshwar Kasirajan, MD ISES 20th Anniversary Events

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Session XI 8:00–10:15AM Off-Label Devices: Justified or Dangerous?

Chairman: Rodney A. White, MD An enthusiastic discussion by world physicians and regulatory experts. A lesson for the practice!

Session XII 10:45-12:00PM CCSVI: Spoof or Reality. Keynote Speaker - Paolo Zamboni, MD Moderators: Edward B. Diethrich, MD and Frank Veith, MD The Evidence for CCSVI in Multiple Sclerosis - Paolo Zamboni, MD The Ultrasound Diagnosis of CCSVI and its Incidence in MS - Andrew Nicolaides, MD Venoplasty Treatment in MS – Techniques and the Buffalo Experience - Nick Hopkins, MD The Effectiveness of Venoplasty for CCSVI – Data and Experience - Donald Reid, MD Endovascular Treatment of Venous Stenoses: Blood Gas Analysis During Venoplasty, Safety and Problems with a Randomized Controlled Trial - Ivo Petrov, MD Evidence Against CCSVI in Multiple Sclerosis - Mark Wholey, MD CCSVI and Multiple Sclerosis – Where do we go From Here? - Frank Veith, MD Luncheon Sessions Session XIII 1:30–3:00 TEVAR: Addressing the Challenges and Complications Acute Type B Dissections: They Are all Complicated Dissections and Should Undergo Endovascular Intervention - Frank Arko, MD Aortic Arch Repair Without Hypothermic Cardiac Arrest - Patrice Bergeron, MD Antegrade Deployment of Stent-Grafts to Extend Open Arch Repair into the Proximal Descending Thoracic Aorta—How Long can you go Safely and Without Risking the Development of Paraplegia - Joseph Coselli, MD Retrograde Type A Dissection During TEVAR: Are Devices With Bare Proximal Stents Inherently More Dangerous? - Frank Criado, MD Complicated Thoracic Coarctation: Management - Luigi Inglese, MD Natural History of Type B Dissection: Strategies to Induce Remodeling and Improve Outcomes - Christoph Nienaber, MD Economic Impact on the United States’ Society of the Implantation of Multilayer Flow Modulator for the Treatment of Type II or III Thoracoabdominal Aortic Aneurysm (TAAA) - Claude Vaislic, MD Aneurysms of the Supra-Aortic Vessels: Management and Treatment in the Endovascular Era - Franco Grego, MD Early Brazilian Experience with the Multilayer Flow Modulator to Treat TAAA - Daniel Benitti, MD

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Session XIV 3:30–5:30 It’s All About Veins: Something for Everyone: Patient Selection, Techniques and Devices Histology of Venous Aneurysms, Varicose and Spider Veins - Ronald Bush, MD Current Status of Treatment Options for Venous Ablation: Open Ligation and Stripping of Saphenous Vein - Mohan Adiseshiah, MD Current Status of Treatment Options for Venous Ablation: Venaceal Closure System - Ian Franklin, MD Current Status of Treatment Options for Venous Ablation: Endovenous Laser Ablation - Ronald Bush, MD Current Status of Treatment Options for Venous Ablation: Mechanico-Chemical Ablation - Richard Mueller, MD What Clinical Conditions Require Pelvic Investigation (US, CTV or MRI) - Mark Meissner, MD Complications With Thermal Ablation and how to Avoid Them - Rajagopalan Ravi, MD Percutaneous Endovenous Intervention for DVT - Mohsen Sharifi, MD Acute DVT: When to Intervene - Patricia Thorpe, MD Bridging With Lovenox: Who, When and Why? - James Williams, MD

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Breakfast Session: Exploring the Future of the Interventional Office Practice Chairman: Warren Swee, MD Session XV Beyond the Basics of Critical Limb Ischemia Chairman: Craig Walker Challenging Case Presentations Throughout Internal Pudendal Artery Stenting for Male Erectile Dysfunction - Narendre N. Khanna, MD Rupture of Thoracic Aorta With Delayed Treatment - Luis Bechara-Zamudio, MD Re-Entry Solutions for Treatment of Chronic Total Occlusion - Leigh Eidson, MD IVC Stenting for Symptomatic Compression Syndrome - Taras Kucher, MD Esophageal Rupture as Late Complication after TEVAR - Samer Koussayer, MD TransApical Delivery of a Modified Thoracic Endovascular Stent-Graft as a Bridge to Definitive Therapy for Contained Rupture of a Recurrent Mycotic Ascending Aortic Pseudoaneurysm - Christian Shults, MD Hybrid Aortic Arch Technique for High-Risk Patients - Ernst Weigang, MD “Time is Tissue”: the Role of Urgent Revascularization in Patients with Infected Diabetic Foot - Pasqualino Sirignano, MD Progression of Abdominal Aneurysm After Previous Open Surgery – the use of Branched Stent-Grafts - Piotr Szopinski, MD Closing Remarks

in d us t r y e x h i b i t s / p a vili o ns

Ex h i b i t ors Contact kkent@azheartfoundation.org to reserve today!

Include a scenic trip to Sedona while you are at iCON2013 Sedona Facts: • The year round population of Sedona is approximately 10,000 (census 2010).

• The elevation of Sedona is approximately 4,350 ft (at Town Hall).

• Sedona has almost 19 square miles, 51% of which are owned by private land owners, while the rest belongs to Coconino National Forest!

• The highest point in Sedona is approximately 5,600 ft (Coffee Pot Rock), and the lowest point in Sedona is approximately 4,000 ft (Oak Creek, Back O’ Beyond Rd).

• The average age is 50.

• We have anywhere from 2 to 4 million tourists per year.

Data • Debate • Resolution

Program Directors: Edward B. Diethrich, MD and Zvonimir Krajcer, MD

iCON2013 invited Faculty Anne L. Abbott, MD, PhD, FRACP Ali AbuRahma, MD Giancarlo Accarino, MD Mohan Adiseshiah, MD, FRCS, FRCP Vlad Alexandrescu, MD Frank Arko, MD Enrico Asher, MD Steven R. Bailey, MD Nilesh Balar, MD Luis Bechara-Zamudio, MD, FACS Alberto Benassi, MD, FACC Amira Benjelloun, MD Daniel Bennitti, MD Patrice Bergeron, MD Giancarlo Biamino, MD Giorgio M. Biasi, MD Emma Birks, MD James H. Black III, MD, FACS Jan Blankensteijn, MD, PhD Raoul Bonan, MD Jan Brunkwall, MD, PhD Clifford J. Buckley, MD, FACS Peter Bungy, MD Ronald Bush, MD, FACS Jacques Busquet, MD Jeffrey P. Carpenter, MD Daniel Clair, MD Gioachino Coppi, MD Joseph Coselli, MD Frank Criado, MD, FACS, FSVM Tony Das, MD Raj Dave, MD Thomas Davis, MD Koen Deloose, MD Eric Dippel, MD Guering Eid-Lidt, MD, FSCAI Mark Farber, MD David Fish, MD Thomas J. Fogarty, MD Ian Franklin, MD

Robert G. Frykberg, DPM, MPH Efraín Gaxiola, MD Franco Grego, MD Igor D. Gregoric, MD Vivek Gupta, MD Peter Harris, MD, FRCS Michel Henry, MD Nick Hopkins, MD Brian Hopkinson, MD, FRCS Luigi Inglese, MD James D. Joye, DO, FACC William H. Julien, MD Alan Karthikesalingam, MD Karthikeshwar Kasirajan, MD Narendre N. Khanna, MD Albrecht H. Kramer, MD Vinay Kumar, MD Christopher J. Kwolek, MD Marty Leon, MD Armando de Carvalho Lobato, MD, PhD Hugo Londero, MD Alan B. Lumsden, MD Lieven Maene, MD Martin Malina, MD, PhD Barry Maron, MD Michel Mawad, MD James May MD, MS, FRACS James F. McKinsey, MD, FACS Thomas O. McNamara, MD Manish Mehta, MD Mark Meissner, MD Amir Motarjeme, MD Richard Mueller, MD Jihad Mustapha, MD Subbararo Myla, MD, FACC Arvinda Nanjundappa, MD, FACC, FSCAI, RVT Jacobo Nettel, MD Andrew Nicolaides, MS, FRCS, PhD (Hon) Christoph A. Nienaber, MD, PhD

Julio Palmaz, PhD Mayank Patel, MD Raghu Patlola, MD Ivo Petrov, MD Dieter Raithel, MD, PhD Venkatesh Ramaiah, MD Rajagopalan Ravi, MD, FACS Allan W. Reid, MD, FRCR, FRCP Donald Reid, MD, FRCS Vincent Riambau, MD Julio Rodriguez-Lopez, MD Gustavo Rubio Argüello, MD Maria A. Ruffino, MD Carlos Ruiz, MD Claudio J. Schönholz, MD

Lewis B. Schwartz, MD Francesco Serino, MD Carlo Setacci, MD Mohsen Sharifi, MD, FACC, FSCAI, FSVM Patricia Thorpe, MD Claude Vaislic, MD S. Rao Vallabhaneni, MD, FRCS, EBSQ-Vasc Jos C. van den Berg, MD, PhD Frank J. Veith, MD Nicolay Volodos, MD Arno von Ristow, MD Ron Waksman, MD Craig R. Walker, MD George Welch, MD Grayson H. Wheatley III, MD Christopher J. White, MD, FACC, FAHA, FESC, FSCAI Rodney A. White, MD Mark H. Wholey, MD James B. Williams, MD, FACS, Paolo Zamboni, MD Christopher K. Zarins, MD Thomas Zeller, MD

Register online at: iconmeeting.org