Anes guidebook DRAFT

2016-2017 DEPARTMENT PROFILE

Department of Anesthesiology

Clinical Care Education Research

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Clinical Care Education Research We provide uncompromising quality in clinical care, research and education. We are compassionate in patient care, creative in research and technology, committed to equipping future global leaders and collaborative within the department, with other departments throughout the university and with institutions across the country and around the world.

Throughout this guide, our values - compassion, creativity, commitment and collaboration- emerge as the keystones of our story.

We are

Compassionate:

We are

Creative:

We are

We are

Offering exceptional perioperative care and pain management to a complex population.

Advancing the frontiers of science, healthcare and technology.

Equipping future global leaders with the latest knowledge and skills.

Working across Vanderbilt University Medical Center and beyond to achieve measurably improved outcomes.

Committed:

Collaborative:

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Message from the Chair Thank you for your interest in the

Vanderbilt University Medical Center Department of Anesthesiology. Our growth and success stem from the foundation of Vanderbilt University Medical Center’s five-pillar commitment to excellence, which consists of people, service, quality, growth & finance, and innovation. Our department follows the Vanderbilt credo, driving us to achieve excellence in healthcare, research and education; we treat others as we wish to be treated; and we continuously evaluate and improve our performance. As the role Warren S. Sandberg, MD, PhD of the anesthesiologist evolves into that Chair, Department of Anesthesiology of a perioperative consultant, our diverse Vanderbilt University School of Medicine team of experts remains at the forefront of knowledge and technology in patient care, research and education.

Our values - compassion, creativity, commitment, and collaboration - emerge as the keystones of our structure and systems, as seen throughout this guide. We are compassionate, not just based on our own assessment, but by what we are being told.

Our patients are recovering faster and with greater comfort through implementation of Enhanced Recovery After Surgery (ERAS) protocols, a collaborative effort led by our faculty, our trainees and our surgical colleagues.

We are creative, advancing the frontiers of science, healthcare and technology. Our informatics infrastructure continues to increase patient safety and clinician effectiveness through innovative methods and novel use of both live and archived data.

Investigators brought in more than $8.0 million in total extramural research funding in 2015-16. This includes more than $4.5 million in awarded NIH grants, which placed Vanderbilt Anesthesiology 9th among U.S. academic anesthesiology departments in NIH funding. Within the department, faculty published 241 papers in 2016, up from 197 papers in fiscal year 2015, within peer-reviewed literature.

Twenty-seven members of the department have been elected into the Association of University Anesthesiologists (AUA).

At the 2015 Annual Meeting of the American Society of Anesthesiologists, department members contributed more than 100 entries, including oral presentations, medically challenging cases, poster presentations, problem-based learning discussions, workshops, panel discussions, and refresher courses.

Our dedicated faculty is committed to equipping graduates for a promising future in anesthesiology. We offer training using cutting edge technology along with opportunities to improve systems of care.

We provide a closely guided mentorship program, balancing subspecialty training, clinical experience and a broad range of academics.

Much of our success can be attributed to the collaboration that occurs across Vanderbilt University Medical Center and beyond. Our clinical teams assisted patients in more than 80,000 encounters last year, spanning the entire spectrum of anesthesiology; for every age group, subspecialty and procedure, caring for patients along their journey to wellness. And we are moving beyond Vanderbilt’s traditional walls. The Vanderbilt Health Affiliated Network is the largest of its kind and growing rapidly, and our department is leading telemedicine and remote presence projects to bring our skills and values to more patients.

As you read through the following pages, we invite you to contact us or visit our website at www.vandydreamteam.com to learn more about our progams.

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Department Leadership Vice Chairs

Suanne Daves, MD Vice Chair, Pediatric Anesthesiology

Stephen Doherty, MMHC Department Administrator

Chief, Pediatric Cardiac Anesthesiology

Matthew McEvoy, MD Vice Chair, Educational Affairs

Brian J. Gelfand, MD Associate Vice Chair, Educational Affairs

Mark Rice, MD Associate Vice Chair, Clinical Affairs

Andrew Shaw, MB, FRCA, FFICM, FCCM Executive Vice Chair

Eric Delpire, PhD Chief, Basic Science Research

Katherine Dobie, MD Chief, Ambulatory Anesthesiology

Brent Dunworth Associate Director for Anesthesia Advanced Practice Nursing, Chief CRNA

Division Chiefs

Edward Sherwood, MD, PhD Vice Chair, Research

Matthew Weinger, MD Vice Chair, Faculty Affairs

David H. Chestnut, MD Chief, Obstetric Anesthesiology

Mias Pretorius, MBChB, MSCI, Chief of Cardiothoracic Anesthesiology

Pratik Pandharipande, MD, MSCI, Chief, Anesthesiology Critical Care Medicine

Ann Walia, MBBS Chief, VA Anesthesiology 5

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Previous Department Chairs

Dr. Benjamin H. Robbins 1946-1961

Dr. Charles B. Pittinger 1962-1969

Dr. Bradley E. Smith 1969-1993

Dr. Charles Beattie 1994-2001

Dr. Jeffrey R. Balser 2001-2004

Dr. Michael S. Higgins 2004-2010

History The Vanderbilt Department of Anesthesiology was one of the first independent departments of anesthesiology in the United States, established on December 12, 1945.

After observing that the battlefield-wounded of World War II were more likely to survive if they received immediate, skilled anesthesia care, Vanderbilt physicians advocated that anesthesiology be established as an autonomous department. At that time, few medical schools possessed an academic anesthesiology service of any type.

This tradition of pioneering in our specialty continues today. Our exemplary faculty provide top-quality clinical services for a full spectrum of medical specialties. Vanderbilt Anesthesiology is recognized as an innovator in perioperative management, healthcare information technology, clincial outcomes research, education and international capacity building. We also have high-caliber basic science and clinical research teams pursuing fundamental and translational knowledge to directly improve patient safety and care.

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About Vanderbilt University Medical Center Vanderbilt University Medical Center named among the “100 great hospitals in America” (Becker’s Hospital Review, 2016) Vanderbilt University Medical Center included among the premier specialty care providers in the nation, as well as the No.1 hospital in the Metro Nashville area and the No. 1 hospital in Tennessee (U.S. News & World Report, 2015)

Vanderbilt University Medical Center named one of healthcare’s “Most Wired” by the American Hospital Association in Hospitals and Health Networks magazine (2016) Monroe Carell Jr. Children’s Hospital named as one of the elite children’s hospitals in the nation, with 10 out of a possible 10 specialties nationally ranked (U.S. News & World Report, 2016)

About Nashville Nashville’s history of country music earned the city its fame as Music City, USA, - but this metropolis is about much more than tunes and twang. Visitors and residents enjoy great dining, entertainment, and cultural life.

Travel to and from Nashville is

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convenient and inexpensive, since the Nashville International Airport is a Southwest Airlines hub. With a growing population of more than 650,000 people, Nashville has been nicknamed “Nowville”

by GQ magazine and called the “It City” by The New York Times.

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Clinical Care We are compassionate, offering exceptional perioperative care and pain management to a complex population.

Serving in one of the largest clinical programs in the nation, the Vanderbilt Department of Anesthesiology’s clinicians provide procedural, critical care, pain management, and all perioperative anesthesia services for more than 100,000 adult and pediatric patient encounters annually at more than 100 anesthetizing locations. Of these, more than 8,000 patients are seen annually in the Vanderbilt Interventional Pain Clinic, and approximately 23,000 Vanderbilt adult and pediatric patients receive anesthetic care during a radiologic, gastrointestinal, or other diagnostic or therapeutic procedure.

The department’s faculty, residents, fellows, certified registered nurse anesthetists (CRNAs), and nurse practitioners provide care in our operating rooms, five adult intensive care units, and the pediatric and neonatal intensive care units, and perform approximately 4,000 anesthetics per year in

the labor and delivery suite.

Our trauma service, which includes the orthopedic trauma program, is among the busiest in the nation and ranked as a Level One trauma facility, with more than 1,700 LifeFlight helicopter transports this year.

The Vanderbilt Preoperative Evaluation Center (VPEC) offers preoperative evaluation before patients undergo procedures at Vanderbilt University Medical Center. In 2015 – for the seventh year in a row – the Vanderbilt University Hospital location of VPEC received a Professional Research Consultants, Inc., patient satisfaction award, the coveted 5-Star Award for Overall Quality of Care.

Our One Hundred Oaks location, which opened in 2009, has received the same award for four years in a row.

The center scored in the 90th – 99th percentiles based on 2014 calendar

year results, compared with similar centers nationwide.

Perioperative medicine is built on full engagement in patient care, from diagnosis to operative recovery. It includes a full-time teaching service with 24/7 consultative availability and extensive use of system-wide information technology and mobile applications to support clinical decision-making, capture data, and measure outcomes, such as the quality of recovery after surgery.

Vanderbilt is one of the few medical training centers with a 3-D transesophageal echocardiography (TEE) simulator, used to teach the essential skill of cardiac ultrasound. Highlighted on the following pages are the services provided by the department’s clinical divisions.

W

“ e’ve initiated a surveillance monitoring project allowing clinicians to stabilize their patients early enough so they do not need to be rescued and escalated to the ICU.

”

Dr. Lisa Weavind, division of Critical Care, Professor of Anesthesiology and Surgery 8

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The perioperative consult service A patient-centered initiative

The Vanderbilt Department of Anesthesiology provides perioperative consult service, offering preoperative evaluation and preparation, intraoperative care, acute postoperative care and pain management, as well as ICU care, to critically ill patients. By providing care before, during and after surgery, patients are receiving better, more standardized care.

Intraoperative care The department has established a system of seamless communication from the operating room to the postoperative care unit (PACU) through innovative methods developed internally by the Vanderbilt Anesthesiology and Perioperative Informatics Research (VAPIR) Division. An electronic notification informs providers on items such as glucose levels, length of stay, unplanned ICU admission and increased creatinine levels. Providers can check their compliance against clinical pathways and compare their practices against departmental aggregate data. These include on-time starts and turnover time, clinical process data and patient care methods. The system uses Vanderbilt University Medical Center’s archive of perioperative patient data from over 932,000 anesthetics, combined with institutional data sources, to foster more integrated care teams.

Post care Enhanced Recovery After Surgery (ERAS) care pathways, initiated in the 1990’s in Europe, are evidence-based protocols designed to improve patient pain control and speed patient recovery for adults and children. Vanderbilt has implemented ERAS protocols in six surgical populations,more than any other healthcare facility in the nation. “In the 2015-2016 year, Anesthesiology interacted with approximately 1200 patients, and through the benefits of ERAS, returned a median 413 bed days back to the hospital by reducing length of stay, resulting in more efficient use of hospital resources,” states Dr. Adam King, clinical chief of the Anesthesia Perioperative Consult Service. Hospital stays are most often extended to address pain control, postoperative ileus and postoperative complications. Because of this, ERAS protocols focus largely on pain management through use of nerve blocks and increased use of non-opioid pain medications, as well as preoperative evaluations to better prepare for surgery.

Pain Management Dedicated teams of pain specialists offer consult services to medical and surgical divisions 24 hours a day, 365 days a year. From post-operative guidance and minor

procedure anesthesia, to complex chronic pain management and surgical intervention, our consultants offer specialized and tailored plans for pain management for a wide range of conditions. “Our focus is collaborative and multidisciplinary; we work with our nurse, surgery, medicine, oncology, palliative care, rehabilitation, and pharmacy colleagues to create systems of care with greater reach across the healthcare system, both inpatient and outpatient,” said David A Edwards, M.D., Ph.D., clinical chief of the Chronic Pain Service.

“We’ve had statistically significant reductions in perioperative opioid consumption,” said pediatric anesthesiologist Andrew Franklin, M.D., MBA, director of Pediatric Pain Management Services. “We have reduced post-operative nausea and vomiting from 14 percent down to zero. So, we’ve nearly eliminated these issues as a result of using regional anesthesia techniques and opioid-sparing, multimodal regimens. We were also able to reduce the median length of stay after starting our protocol from 3.3 days to 2.3 days. Because of these improvements, we’re able to get our patients mobile more quickly and get them home sooner.”

Hip surgery patient Shelbey Mitchell, center, with Andrew Franklin, M.D., MBA, and Jenna Sobey, M.D., part of the Pediatric Perioperative Interdisciplinary Surgery Home team that devised new strategies to improve the surgical recovery process. (photo by Susan Urmy)

“The first time I was in the hospital, I couldn’t eat at all. I either felt sick or my leg was hurting too much. With the second surgery, there was not as much pain, and I was more ‘with it’ because I wasn’t on a pain pump. I could actually talk to my friends and family and not feel loopy. And, I wanted food right after I woke up.”

Shelbey Mitchell, patient

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Division of Ambulatory Anesthesiology

The Division of Ambulatory Anesthesiology is led by Katherine Dobie, MD, and consists of 12 faculty members and 30 nurse anesthetists who practice in two on-campus locations and two off-campus locations. The trend in surgical healthcare continues toward significant growth for outpatient surgeries; it is now estimated that more than 70 percent of all surgeries are performed in the outpatient setting. The Division of Ambulatory Anesthesiology is committed to addressing this trend innovately as we explore how to safely care for sicker patients undergoing more complex surgeries across the entire episode of care within the outpatient surgical home. Ambulatory Anesthesiology is

unique compared to other academic departments, with its high volume (estimated ~20,000 cases for FY 2015) and its joint venture with private physicians in the greater Nashville area.

The Vanderbilt Outpatient Surgical Home (VOSH) was created within the division. Patient care within the home begins with a systematic preoperative screening selection and continues with prescription of care pathways and postoperative day one follow-up. Services are provided for Vanderbilt University Medical Center satellite locations that include Cool Springs Surgery Center, Medical Center East, Vanderbilt Bone and Joint Surgery Center, and Vanderbilt Outpatient Surgery. These centers provide for a broad base of cases,

including spine, surgical oncology, pain, GI, orthopedic, pediatric, ENT, urologic, neurosurgical, general surgery, and higher-acuity plastic. The division houses three resident rotations where residents rotate to four centers.

One of these rotations provides the majority of the acute pain and regional procedures for the residency, including management of an outpatient continuous peripheral nerve block (athome catheter) program.

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Division of Anesthesiology Critical Care Medicine

The Division of Anesthesiology Critical Care Medicine (ACCM) is led

by Pratik Pandharipande, MD, MSCI. The division provides critical care services in the burn ICU, cardiovascular ICU, neurological ICU and surgical ICU at Vanderbilt Medical Center, and in the surgical ICU at the VA Medical Center in Nashville. Additionally, division members provide perioperative anesthetic care for patients undergoing major surgery, and some participate in the perioperative consult service.

The division includes 24 anesthesiology-intensivists, along with more than 35 acute care nurse practitioners (ACNPs) and physician assistants (PAs), making it one of the largest anesthesiology critical care medicine divi-

sions in the country. Additionally, there are eight neurointensivists, certified by the United Council for Neurologic Subspecialties. The ACNPs and PAs have faculty appointments in the department, and an ongoing alliance between the ACCM Division and the School of Nursing also supports an ACNP intensivist training program.

The division strives to provide excellent patient care, promote education, and engage in scholarly activity. Faculty and fellows keep abreast of modern technology and the changing spectrum of caring for the critically ill. This includes proficiency in ultrasound, echocardiography, and management of patients with ventricular assist devices or who are on ECMO.

The ACCM Fellowship has recently been approved for 10 ACGME-accredited fellowship positions per year and has received accreditation for five years.

Fellows have a diverse clinical experience through our subspecialty ICUs and an innovative didactic program.

Division faculty frequently participate in regional, national and international educational activities and have taken on leadership roles in national organizations such as SCCM, ASA, SOCCA and the American Delirium Society; in VUH and VUMC administration including the directorship of the BICU, NCU, CVICU and CELA, and in the medical school curriculum redesign, via innovation immersion programs.

Active research programs encompass clinical and translational research that focuses on perioperative risk factors and mechanisms of cognitive impairment, kidney injury, sepsis and its monitoring, education and implementation science, health resource utilization, multisensory training, device development and quality improvement projects, including remote bedside monitoring and use of rapid response teams. Active grants in the division include two RO1s, a K23 training grant, an RO3 grant, and a FAER Research in Education grant, in addition to smaller industry and VICTR grants. Faculty have been involved in more than 20 peer-reviewed manuscripts and textbook chapters in the last academic year.

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Division of Cardiothoracic Anesthesiology

The Division of Cardiothoracic Anesthesiology is led by Dr. Andrew Shaw and includes 14 faculty members and 11 nurse anesthetists. Each month, three residents rotate through the service. The fellowship program, under the leadership of Dr. Mias Pretorius, currently trains three clinical fellows per year and will expand to 5 fellows in 2016.

The division provides perioperative care for approximately 1,500 adult cardiac procedures a year. These include CABG (on- and off-pump), valvular surgery, heart and lung transplantation, adult congenital procedures, hybrid procedures, aortic surgery, and ventricular assist device (VAD) insertions. The VAD program at Vanderbilt

currently places about 100 devices per year for both bridge-to-transplant and destination therapy indications. The transcatheter aortic valve replacement (TAVR) program began in 2011 and has now grown to over 150 cases per year.

Members within the division provide anesthetic care to over 700 general thoracic cases annually. In addition, anesthesia services are also provided for interventional pulmonology, cardiology, and electrophysiology procedures, which together account for approximately 3,500 cases annually. A subset of the division’s faculty rotate through the adult cardiovascular intensive care unit, under the medical direction of division faculty member Tony Hernandez, MD.

Intraoperative transesophageal echocardiography (TEE) is an integral part of our clinical practice and is performed on all adult cardiac patients. Our faculty also provide TEE in the EP suite to rule out thrombosis of the left atrial appendage, to guide trans-septal puncture, and to guide transcatheter valve procedures.

All studies are performed and interpreted by a cardiothoracic anesthesiologist, and cases are digitally archived for future study. The division uses 4 Philips EPIQ and 3 CX50 consoles, and these machines were installed in 2015.

Division faculty conduct research in vascular biology, precision perioperative medicine, acute kidney injury, and the perioperative inflammatory response. Extramural grant support

comes from the Department of Defense, National Institutes of Health and Industry.

The division has a significant education presence. Dr. Shaw serves as scientific program chair for the Society of Cardiovascular Anesthesiologists (SCA) annual meeting. Julian Bick, MD, recently received a $100,000 Research in Education Grant from the Foundation for Anesthesia Education and Research which is used to train CA-1 residents in TEE. Two simulators are available for training in the division’s echocardiography lab and at Vanderbilt’s Center for Experiential Learning and Assessment.

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Division of Multispecialty Adult Anesthesiology

The Division of Multispecialty Adult Anesthesiology is led by Mark Rice, MD. This is the department’s largest division, providing perioperative anesthetic care for more than 12,000 patients annually in 45 operating rooms and procedure suites for a wide variety of surgical services, including general surgery, orthopedics, urology, plastic surgery, ophthalmology, vascular surgery, otolaryngology, hepatobiliary surgery, liver and renal transplantation and oral/maxillofacial surgery.

The division has 48 full- and part-time faculty members, most of whom have significant subspecialty training and expertise. As Vanderbilt is a Level 1 Trauma Center, MSA faculty and staff provide 24-hour coverage for emergency and trauma surgery for the region.

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In July 2014, a Perioperative Consultative Service was created to provide co-management of surgical patients, from decision to operate until after discharge from the hospital. This started with a pilot program involving colorectal surgical patients and quickly grew to include abdominal wall reconstruction, surgical weight loss and hepato-biliary-pancreatic/surgical oncology patients. Plans are underway with other surgical services to extend this coverage to another two services within the next year.

MSA division faculty provide anesthesiology residents a variety of both introductory and advanced clinical experiences and make numerous contributions to the department’s educa-

tional programs for medical students, residents and fellows. Additionally, MSA faculty members teach and supervise residents from other specialties, as well as student registered nurse anesthetists who rotate in the MSA division. Division faculty members pursue a wide range of academic interests, including regional anesthesia, airway management, information technology, perioperative cognitive dysfunction, echocardiography, ultrasound imaging and perioperative medicine.

The division’s members are also highly active in research, with numerous investigator-initiated clinical research projects currently in progress. Work is ongoing in informatics, regional anesthesia, airway management, perioper-

ative medicine and drug protocols in an effort to improve perioperative care and throughput.

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Division of Neuroanesthesiology

Neurosurgery and other neurologic services continue to expand at Vanderbilt University Medical Center, and faculty members specializing in neuroanesthesiology are providing increasingly complex anesthesia and sedation services.

The Vanderbilt Department of Neurological Surgery currently has the highest volume of deep brain stimulator implantations in North America. The Vanderbilt Brain Tumor Center provides comprehensive care for patients with brain tumors, and more than 400 major brain tumor operations are performed annually. Because of increasing case volumes, two new neu-

rointerventional neurosurgeons have recently joined Vanderbilt, operating in our state-of-the-art interventional radiology rooms dedicated solely to neurosurgical procedures. The Joint Commission designated Vanderbilt as an Advanced Certification Comprehensive Stroke Center, where the most complex of stroke patients are treated.

Annual surgical volume is approximately 4,800 neurologic cases per year.

The Division of Neuroanesthesiology engages in research aimed at improving patient outcomes and cost-effectiveness, as well as expanding the clinical knowledge of certain diseases. Paramount to the success of the division

is the collegial working relationship among operating room and intensive care unit team members.

VUMC has seven designated neurosurgical operating rooms, where anesthesia services are provided for operations, including brain tumor, blood vessel malformation, aneurysms, stroke intervention, trauma, complex spinal procedures, functional neurosurgery and chronic pain management. The Division of Neuroanesthesiology also provides specialized anesthesia services for “awake craniotomies,� when patients are intermittently awake to facilitate speech and motor mapping during surgery in order to preserve the most

vital areas of the brain. Additionally, anesthesia is provided by the division in neurointerventional radiology suites and at Monroe Carell Jr. Children’s Hospital at Vanderbilt. Like their surgical colleagues, neuroanesthesiologists face many unique challenges, including the length of procedures (which may last more than 16 hours), unusual patient positioning and unexpected intraoperative events, such as seizures or intracranial hemorrhage. Residents on the neuroanesthesia rotation, as well as the faculty leading the training, discover that the ability to make an immediate impact on an operation is both exciting and gratifying.

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Emery A. Rovenstine Memorial Lecture

Division of Obstetric Anesthesiology

Dr. David Chestnut was

the 2016 ASA Rovenstine

Brenda A. Gentz, M.D., Chair Committee on Annual Meeting Oversight

Lecturer. The lecture is Professionalism is a crucial component to the practice of medicine. The talk by 2016 Rovenstine Lecturer David H. Chestnut, M.D., is intended to annual meeting of the motivate audience members to re-explore some of the American Society of most fundamental questions about their careers and lives.

“I hope this lecture will help attendees remember why Anesthesiologists (ASA). they chose to become a physician,” said Dr. Chestnut.

His talk will focus on affirmation of professionalism Dr. David Chestnut as one of the six core competencies for physicians, and address the limitations of written codes and rules that promote physician professionalism.

Dr. Chestnut will also help to identify personal attributes, commitments, behaviors, interactions, and influences important to the development and maintenance of professionalism in physicians.

Perhaps most important, Rovenstine Lecture attendees will take away new insights into the dynamic nature of professionalism and the critical role it plays in the health care The Division of Obstetric Anesthesi- complement of techniques forcommunity. labor the nation. Approximately 15 of these “Professionalism something that learn once,” annually at ology is led by David Chestnut, MD. analgesia, the division provides con-is not procedures areweperformed said Dr. Chestnut. “Professionalism is both a commitChestnut completed the fifth edition sultation and critical care management VUMC. ment and a skill that we must practice throughout our of Chestnut’s Obstetric Anesthesia: services for high-risk obstetric patients, career. And all of us need somedivision help and encouragement The also collaborates with Principles and Practice in 2014. A com- as well as specialized anesthesia care for VUMC maternal-fetal medicine, gyalong the way.” prehensive reference, this volume is fetal surgery.

David H. Chestnut is currently Professor of necologic oncology and urology physiAnesthesiology and Chief of the Division of Obstetric considered to be the “bible” of obstetric The resumption of in utero repair of fecians in an innovative approach to the Anesthesiology at Vanderbilt University Medical anesthesia. tal myelomeningocele,Center a procedure piin Nashville. care of patients with placenta accreta/ The division provides dedicated, 24- oneered at VUMC in 1997, has a formfor of abnormal, He hasbrought served as percreta, president which of the isSociety hour, in-house obstetric anesthesia care an added dimensionObstetric of specialized invasive placentation that places the Anesthesia and Perinatology, and for three he was ASA’s to theatAmerican College of for approximately 4,500 deliveries at clinical service to the years division.

The re- liaison mother high risk for massive blood Obstetricians and Gynecologists.

He is a diplomate of Vanderbilt University Medical Center sults of a seven-year National Institutes loss and significant morbidity. both the American Board of Anesthesiology (ABA) (VUMC) annually - over half of which of Health-funded trial, Management During the past year, approximately 15 and the American Board of Obstetrics and Gynecology. are considered high risk. The division of Myelomeningocele For Study (MOMS), parturients 12 years (1997-2009) he servedwith as aknown Directorplacenta of accrealso provides anesthesia services for ap- demonstrated a clear benefit forwhich babies the ABA, he also served as president.

In 2009, ta/percreta have undergone a modified proximately 2,500 gynecologic surgical who undergo fetal surgery for treatDr. Chestnut was appointed ABAdelivery Executive through Director a fundal cesarean for Professional a position he held for five years. procedures in a suite of three operating ment of spina bifida. These surgeriesAffairs, re- uterine incision, and the placenta was He served as the ABA representative to the Board of rooms adjacent to the labor and deliv- sumed at VUMC in 2011, and patients Brenda A. Gentz, M.D., is left in situ, with plans to perform hysDirectors American Board of Medical Specialties ery unit. In addition to offering full of Anesthesiology, are referred to VUMC fromof the across Associatethe Professor weeks postpartum. This (ABMS), and for three terectomy years he also six served as a member Banner University Medical Center-Tucson, Tucson, Arizona. of the ABMS Executive Committee.

the premier event at the

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multidisciplinary approach seems to result in decreased maternal blood loss and morbidity, and it is a focus of ongoing assessment.

The division is taking a leadership role in the use of in situ simulation training for obstetric emergencies. Ongoing clinical research projects include: 1) assessment of delayed delivery of the placenta and hysterectomy in patients with placenta accreta/percreta, and 2) assessment of resident and student communication skills in conversations with patients with limited English proficiency, which has led to better communication with patients with limited English proficiency.

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Division of Pain Medicine

Clinicians at VUMC’s Interventional Pain Center utilize a multidisciplinary approach to pain care, offering thorough evaluations, consultations, and referrals in order to employ the most advantageous treatment modalities.

The Interventional Pain Center sees patients with all types of pain, including back, neck, abdominal, pelvic, nerve and joint pain, as well as chronic headache. During the first clinic visit, a patient’s medical his-

tory is thoroughly reviewed, and his or her condition is evaluated by Vanderbilt pain specialists to develop a team-based treatment plan. This team includes specialists from anesthesiology, psychology, psychiatry, neurology, neurosurgery, orthopedics or rehabilitation. Interventional Pain Center physicians also work closely with a patient’s primary care providers to close the loop effectively and foster shared responsibility for patient health.

Monroe Carell Jr. Children’s Hospital at Vanderbilt is the site of a unique pediatric pain clinic, where Vanderbilt providers work with patients, their families, and their physicians to provide the best pain management for the pediatric patient’s specific needs.

The Neonatal Intensive Care Unit at the Children’s Hospital also has its own specialized pain management program, and there is a regional anesthesia program to treat young patients as well.

The Comprehensive Pain Service (CPS) at VUMC also continues to grow, as patients benefit in increasing numbers from epidural catheters, peripheral nerve blocks, and peripheral nerve catheters for pain management for complex shoulder and arm surgery, lower extremity surgeries, and repeated burn debridements.

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Division of Pediatric Anesthesiology

The Division of Pediatric Anesthesiology is led by Suanne Daves, MD. The Division provides perioperative care for more than 13,000 patients annually at the Children’s Hospital, making it the region’s major pediatric referral center.

The Pediatric Pain Service provides an increasing number of inpatient consultations and works closely with the many surgical services at the Children’s Hospital to provide a full spectrum of perioperative pain management strategies.

Education and training of medical students, anesthesia residents, nurses, and associated healthcare personnel is a major faculty commitment. Amanda Lorinc, MD, assistant professor of Anesthesiology, leads the newly-launched Pediatric Liver Transplant Program.

Areas of academic interest for the division’s faculty include safe transfusion practices, multidisciplinary approaches to decreasing surgical-site infections, situational awareness during hand-overs in care, difficult airway management, pediatric pain management, regional anesthesia, extracorporeal membrane oxygenation (ECMO),

and perioperative care of cardiovascular patients.

The division is an active member of Wake Up Safe, a quality improvement initiative of the Society for Pediatric Anesthesia. Wake Up Safe is a Patient Safety Organization (PSO), as defined

by The Patient Safety and Quality Improvement Act of 2005, and its participants are leading children’s hospitals throughout the country. Through voluntary reporting from its member institutions, Wake Up Safe has developed the first-ever national registry of adverse perioperative events in pediatric

patients. Its goal is to help define quality in pediatric anesthesia and develop quality improvement systems in an effort to help improve anesthetic care for children of all ages.

The division is also an active partner with the quality improvement office of the Children’s Hospital and participates in Solutions for Patient Safety, a national network of more than 80 children’s hospitals in 34 states that partners with Child Health Patient Safety Organization (PSO), the nation’s only PSO dedicated to the safety of hospitalized pediatric patients.

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Division of Pediatric Cardiac Anesthesiology The Division of Pediatric Cardiac Anesthesiology, led by Suanne Daves, MD, was formed in 2007 to support the Children’s Hospital. Children with heart defects represent a complex group of patients who often require intensive surgical repairs to thrive or even survive into adulthood. The Pediatric Heart Institute at the Children’s Hospital is a high-volume regional referral center and is ranked 17th in US News and World Report’s list of top hospitals in the care of pediatric patients with congenital heart disease.

Two new areas of focus for the divi-

sion’s quality improvement efforts are decreasing the incidence of early surgical re-intervention in the cardiac surgical patient and identifying effective strategies in the prevention of catheter-related venous thrombosis in the pediatric cardiac population.

Training pediatric anesthesiology fellows in the care of the critically ill child undergoing cardiac surgery or catheterization is a core mission of the division.

Fellows spend two months on the cardiac service, and many elect to spend part of their training in the cardiac critical care unit.

Dr. James Phythyon Endowed Lectureship in Pediatric Anesthesiology Since 2005, the Dr. James Phythyon Endowed Lectureship in Pediatric Anesthesiology has brought renowned experts in the field to Vanderbilt’s campus as visiting professors.

The lectureship was established by the family of Dr. James Phythyon, a founding member of the Pediatric Anesthesiology Division. Dr. Phythyon’s widow, Mrs. Marlin Sanders, and the couple’s daughters, Mary Neal Meador, Elizabeth Donner, and Sarah Miller, are strong supporters of the department. Each year, they attend the lecture and other events in honor of Dr. Phythyon. In 2016, Patrick Guffey, MD, presented a well-received Grand Rounds lecture on “The National Anesthesia Incident Reporting System.”

Patrick Guffey, MD, Warren S. Sandberg, MD, PhD, Sarah Miller, Suanne Daves, MD, Elizabeth Donner, Marlin Sanders, Madolyn Miller, Andrew Shaw, MB, FRCA, FFICM, FCCM 18

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Veterans Affairs Anesthesiology Service

The Veterans Affairs Anesthesiology Service is led by Ann Walia, MBBS. The division provides perioperative patient care services for more than 10,000 procedures annually at the Veterans Administration Medical Center in Nashville and the medical center at the Alvin C. York campus in Murfreesboro, Tennessee. These two facilities make up the core of the Tennessee Valley Healthcare System (TVHS), which also includes 11 community-based health clinics.

Areas of particular clinical interest in the division include airway management and ultrasound-guided regional anesthesia. The group also supports an active PreAnesthesia Evaluation Clinic, with an annual workload of more than 5,000 visits. The service also provides primary coverage for the VA Surgical Intensive Care Unit, acute and

chronic pain management, and emergency airway management.

This year, the Division initiated a Perioperative Care service for selected surgical services, with the goals of decreasing ICU and hospital length of stay, improving patient satisfaction and improving coordination of care. The Chronic Pain Management center is located at the Murfreesboro campus, and the team there provides a comprehensive set of services.

“Even though 80 percent of our surgical patients are classified as ASA3 and 4, our morbidity and mortality rate is lower than the national average,” said Veterans Affairs Anesthesiology Service Chief Ann Walia, MBBS. “We have a great team here, and they work hard to provide excellent care to our veterans.”

The TVHS Anesthesiology Service was one of the first in the nation to implement e-Consults for preoperative anesthesia evaluations. This initiative saves the patient’s travel cost incurred by the VA, and decreases unnecessary testing.

This has increased both patient and provider satisfaction. The TVHS has also been selected as a beta test site for the National Surgical Quality and Workflow Management initiative.

Certified Registered Nurse Anesthetists The Vanderbilt Department of Anesthesiology embraces collaborative practice in its approach to patient care, involving anesthesiologists and residents, certified registered nurse anesthetists (CRNAs), student registered nurse anesthetists (SRNAs) and anesthesia technicians. Serving as Chief CRNA and Associate Director, Anesthesia Advanced Practice Nursing, Brent Dunworth, MSN, MBA, APN, CRNA, leads the CRNA Division.

The more than 140 CRNAs in the division provide anesthesia for all types of surgical procedures, including cardiac, pediatrics, vascular, trauma, neurosurgery, plastics, radiologic and special procedures.

CRNAs administer general, regional and monitored anesthesia care for scheduled and emergency surgical, obstetric, and diagnostic procedures.

CRNAs’ key responsibilities include preoperative patient evaluation, management of the patient through completion of the operative procedure, safe transport of the patient to the recovery area and assurance of the appropriate postoperative care.

Additionally, CRNAs provide instruction and education for student nurse anesthetists (SRNAs). They also support the residency education mission by providing service coverage to allow residents to attend educational activities and participate in elective rotations. Our CRNAs are full partners in department clinical practice initiatives and frequently contribute to the development of quality improvement and efficiency initiatives. Thus, the CRNAs are

essential to many core endeavors.

In terms of personnel, the CRNA division is the largest within the Department of Anesthesiology.

Vanderbilt is the primary clinical affiliate of the Middle Tennessee School of Anesthesia (MTSA) in Madison, Tennessee, which is the second largest nurse anesthesia program in the country. Vanderbilt is also a clinical affiliate for the Union University Nurse Anesthesia program in Jackson, Tennessee. Student nurse anesthetists assist in approximately 7,000 anesthetics per year while on Vanderbilt rotations.

The CRNA division mirrors the VUMC operating room organization. CRNAs who serve in a lead or service specialist position facilitate communication with all members of the patient care team. In addition to SRNA training, the CRNA division has developed strong continuing education unit-eligible educational programs designed specifically for CRNAs. Vanderbilt CRNAs are always positioned on the cutting-edge of new developments in anesthesiology.

VUMC is staffed by 38 anesthesia technicians who contribute to safe, efficient anesthesia care by providing highly skilled assistance to anesthesiologists and nurse anesthetists at both on- and off-campus clinical locations.

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Education We are committed, equipping future global leaders with the latest knowledge and skills.

The Office of Educational Affairs supports and oversees undergraduate medical education, graduate medical education for residents and fellows, and continuing education for faculty and advanced practice nurses. The extensive education and training programs offered by the Department of Anesthesiology prepare medical students, residents, fellows, nurses, and faculty for productive careers as clinicians, academicians, and scientists. We offer ACGME-accredited fellowships in Adult Cardiothoracic Anesthesiology, Anesthesiology Critical Care Medicine, Pain Medicine, Pediatric Anesthesiology, Obstetric Anesthesiology and Clinical Informatics. We also offer fellowships in Regional Anesthesiology and Global Anesthesiology.

Residents and fellows benefit from in-depth training in all subspecialty disciplines of clinical anesthesiology, critical care, and pain medicine. A full

calendar of continuing medical education opportunities for faculty, residents, fellows, nurse anesthetists, and nurse practitioners is in place, including: •Grand Rounds, which features leading experts from around the world; •Mortality, Morbidity & Improvement (MM&I) Conferences, which focus on recent cases with the goal of improving patient care; •ABA BASIC and ADVANCED EXAM Prep Series, which are designed to prepare CA-1s and CA2/3s, respectively, for their high-stakes exams as part of the sequence of board certification; •Mock Oral Board Exams, which are given twice a year to CA1, 2, and 3 residents in order to prepare them for this portion of the ABA APPLIED exam; •Simulation Training Program, which includes Milestone-based assessment in order to give residents training in

rare, high-stakes events, as well as to prepare them for the OSCE portion of the APPLIED Exam; •BH Robbins Scholar Program, which offers one-on-one mentorship and collaboration for aspiring physician-scientists preparing for careers as academic anesthesiologists; •Faculty Development Seminars, which provide targeted training for professional development; •Combined Integrative Health and Pain Medicine Quarterly Rounds, which focus on issues related to the management and treatment of pain.

We offer a wide-range of learning opportunities that parallels our excellent clinical training and development. As a result, the average score of Vanderbilt anesthesiology residents on in-training exams is in the 75-80th percentile when compared to the nation.

“We view everyone as lifelong learners.”

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Office of Educational Affairs Faculty and Staff

Residents The department’s fully accredited residency program is highly sought after by the nation’s top medical students. Proof of this is in the numbers: in the 2015 National Residency Match, the department received more than 800 applications for 18 positions.

Vanderbilt Anesthesiology’s four-year residency program currently enrolls 18 resident physicians per year. Our physician educators are nationally and internationally recognized as leaders in their fields, and the department successfully supports residents interested in academic anesthesiology so they can develop careers focused on advancing knowledge in the specialty. The department typically has 25-30 residents who present original research and overviews

of challenging cases at national meetings every year, a clear indication that the department’s educational programs are creating physician-scholars who are prepared for medical practice, peer-education, and scientific investigation.

The department’s educational program for residents and fellows consists of a combination of comprehensive didactic conferences, mentored clinical training by subspecialists in every domain of anesthesiology, simulation training, and self-study. Simulation training features prominently in the cognitive, procedural, and teamwork aspects of anesthesia education, and Vanderbilt University School of Medicine’s Center for Experiential Learning and Assessment is a nationally renowned, on-campus resource for this training.

The Accreditation Council for Grad-

uate Medical Education (ACGME) core competencies form a framework for the training program, and a major curricular revision is underway that is targeting the new ACGME Milestones system, as well as the recent changes to the ABA Certification process.

The goal of ongoing curriculum development and revision in the Milestones era is to continue to achieve or exceed this level of academic achievement.

Director of Educational Research and Curriculum Development Leslie Fowler, MEd, is overseeing the department’s curriculum improvements. Among other projects, Leslie is working with the School of Medicine’s VStar team to develop a “flipped classroom” model of learning for anesthesiology education.

VStar is the school’s new IT platform for learning management, launched in

2014. The flipped classroom is a learning environment in which course content is accessed by learners outside of the classroom, and classroom time is used for interactive projects and discussion. Once the flipped classroom is complete, anesthesiology residents at every level of training will have access to rotation-specific curriculum and learning modules 24 hours a day. Our faculty are also developing the same concept for nurse anesthetist training in East Africa.

Fellows Building from the department’s strength in subspecialties, seven clinical fellowships, as well as a research fellowship, are offered to individuals seeking advanced, focused training.

The following clinical fellowships are offered at Vanderbilt:

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Advanced Practice Nurses The Department of Anesthesiology has a unique partnership with the Vanderbilt University School of Nursing to offer an Acute Care Nurse Practitioner (ACNP) Intensivist track as part of the ACNP master’s degree program. The program combines the didactic training of the School of Nursing’s ACNP Program with supplemental specialty lectures in critical care medicine. Students perform their clinical rotations in seven of the Vanderbilt and VA ICUs. Students also receive additional exposure to ICU medicine through twice-monthly simulation sessions and weekly clinical case conferences, taught jointly by members of both faculThe Anesthesia Summer Internship Proties. Additional partnership program provides an opportunity for undergrams between the Anesthesiolgraduate and medical students to particiogy Department and the School pate in research projects with our faculty. of Nursing are being planned.

The program receives funding from FAER Vanderbilt University Medical and NIH to support summer student interns and is a part of the NIH Short Term Training Center is one of the largest emProgram for Minority Students (STTP) ployers of nurse practitioners in the country, and the Division of Anesthesiology Critical Care MedAdult Cardiothoracic Anesthesiology* – icine has 35 Acute Care Nurse Prac3 fellows titioners who work in intensive care Clinical Informatics-1-2 fellows* settings.

Anesthesiology-Critical Care Medicine* – 10 fellows Global Anesthesiology** – 1-2 fellows Nurse Anesthetists The continuing education of more (first fellowship awarded in 2016) than 100 Certified Registered Nurse Obstetric Anesthesiology* – 2 fellows Anesthetists in the department is supPain Medicine* – 3 fellows ported with recurring programs, inPediatric Anesthesiology* – 4 fellows cluding Grand Rounds and Mortality, Regional Anesthesiology** – 2 fellows Morbidity & Improvement (MM&I) *ACGME Accredited Conferences. In addition, Vanderbilt **ACGME Accreditation not offered

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is a primary clinical affiliate of the Middle Tennessee School of Anesthesia (MTSA) in Madison, Tennessee, and of the Union University Nurse Anesthesia program in Jackson, Tennessee. Student nurse anesthetists participate in approximately 7,000 anesthetics per year while on Vanderbilt rotations, and their on-campus training is coordinated by the Department of Anesthesiology.

The Center for Experiential Learning and Assessment (CELA) CELA offers medical learners at all levels a simulation education on computerized, life-like mannequins.

Participants get hands-on training in anesthesiology airway management, critical care, perioperative management, and transesophageal echocardiogram procedures.

CELA was endorsed by the American Society of Anesthesiologists (ASA) as one of approximately 40 centers in the nation officially approved to deliver certified educational programs. Anesthesiologists can receive continuing medical education (CME) simulation training at CELA that qualifies for American Board of Anesthesiology Maintenance of Certification in Anesthesiology (MOCA®) credit. To achieve the ASA endorsement, the CELA program met strict criteria, including having strong leadership and the necessary equipment, facilities, and personnel to provide consistent, effective training.

Maintenance of Certification in Anesthesiology (MOCA®)

MOCA® simulation courses are taught at Vanderbilt’s Center for Experiential Learning and Assessment (CELA), where state of the art immersive patient simulation training is offered.

Arna Banerjee, MBBS, assistant dean for Simulation in Medical Education and Administration and associate professor of Anesthesiology, Surgery and Medical Education

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Building Safe Anesthesia Capacity Around the World Vanderbilt’s Department of Anesthesiology is commited to improving perioperative and anesthetic care in medically underserved regions of the world. VanderDr. Mark Newton bilt International Anesthesia (VIA) is developing interactive curricula and training providers who will practice around the world.

ImPACT Africa (Improving Perioperative & Anesthesia Care and Training in Africa) is a sustainable training program that aims to improve perioperative outcomes related to surgical interventions through the ongoing training of skilled anesthesia providers. This program has a particular focus on improving maternal, infant,

and trauma-related morbidity and mortality in the perioperative period.

educate medical staff in anesthesia and pain management services.

As part of the ImPACT program, the department received over $4 million in grant funding from the GE Foundation’s Developing Health Globally program to support research in curriculum development and capacity-building in Kenya and other low-resource regions of the world. Dr. Mark Newton and Dr. Matt McEvoy serve as co-PIs.

Vanderbilt Anesthesia Global Health and Development

Newton directs the Vanderbilt International Anesthesia (VIA) program and divides his time between being a pediatric anesthesiologist at Vanderbilt and serving as chief anesthesiologist for Kijabe Hospital in rural Kenya.

Under his guidance, Vanderbilt anesthesiologists, residents, fellows, and nurse anesthetists in the training program travel to Kenya for training and

The mission of VIA includes training anesthesia providers and others in trauma care.

Trauma is primarily a surgical disease that is taking, on average, 1.24 million lives a year. Ninety one percent of trauma cases occur in the poorest countries and affect ages 15 – 29. Road traffic injuries are the leading cause of trauma fatalities and injuries.

Dr. Kelly McQueen

Dr. Kelly McQueen is director of Vanderbilt Anesthesia Global Health and Development and Vanderbilt Global Anesthesia Fellowship and a globally recognized expert in the field.

McQueen, is leading the effort as principal investigator of two recently applied for grants: one in Ethiopia and the other in Mozambique. Through a collaborative effort with Dr. Susan Eagle and the Vanderbilt Department of Engineering, the development of smart health devices is underway, and are they expected to impact trauma disability and death through early diagnosis of blood loss and critically low blood pressures. In countries like Ethiopia and Mozambique, few basic monitors are available – even basic blood pressure cuffs are often not available when needed most.

Educational Research The department is a national leader in rigorous educational research. Dr. Scott Watkins (APSF), Dr. Chris Cropsey (FAER), and Dr. Mary DiMiceli-Zsigmond (GE Foundation) all have grant-funded educational research investigating the use of decision support tools to improve team-based care delivery in high-stakes perioperative events in pediatric, general adult, and obstetric populations,

respectively.

Dr. Julian Bick (FAER) investigates the effect of near real-time feedback on the rate of competency acquisition in basic TEE. Dr. Bantayehu Sileshi (GE Foundation) focuses on the implementation of a novel perioperative data collection tool in low and middle income countries and the development of anesthesia curricula for nonphysician anesthesia providers.

Scott Watkins, MD and Mary DiMiceli-Zsigmond, MD

Left: Bantayehu Sileshi, MD Center: Julian Bick, MD Right: Chris Cropsey, MD

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Research We are creative, advancing the frontiers of science, healthcare and technology.

The vision of the Research Division, is to improve upon the department’s currently successful program by fostering excellence, collaboration, and the development of young investigators in anesthesiology.

In federal fiscal year 2014, the Vanderbilt University School of Medicine (VUSM) ranked 10th among U.S. medical schools for National Institutes of Health (NIH) funding, and VUSM funding from all sources has more than doubled since 2001.

Investigators brought in more than $8 million in total extramural research funding. This includes more than $4.5 million in awarded NIH grants.

Within the department, faculty published 241 papers within the last 12 months, up from 197 papers

in fiscal year 2015, within peer-reviewed literature.

Anesthesia clincal research centers include Vanderbilt Anesthesiology Clinical Research Advisory Committee (VACRAC) and Vanderbilt Anesthesiology & Perioperative Informatics Research (VAPIR).

VACRAC reviews research protocols with a panel of experienced investigators. This process has improved the design and execution of clinical research projects, resulting in more rapid and effective study origination and completion.

VAPIR, led by Chief of the Informatics Research Division, Dr. Jonathan Wanderer, has strengthened internal communication and plays a vital role in providing superior perioperative care. The Division collaborates

“Quote.”

internally with colorectal surgeons to understand the relationship between interoperative hypothermia and surgical site infections.

The team also creates innovative techniques for efficient communication with clinicians to improve patient care. Through the development of automated email systems and dashboards, VAPIR has strengthened internal communication and plays a vital role in providing near real time feedback to clinicians to help them improve perioperative care.

The Vanderbilt Department of Anesthesiology has a strong, multifaceted approach to research, which can be viewed on the following pages. View more at www.vandydreamteam.com.

Andrew Shaw, MB, FRCA, FFICM, FCCM Executive Vice Chair 25

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Lab Research Advancing Medical Science The annual Anesthesiology Research Symposium

Highlighting the current research of clinical and translational investigators and basic scientists Symposium Awards Charles Bernard Pittinger Prize-Basic Science Research | Brad Grueter, PhD Charles Bernard Pittinger Prize-Clinical Translational Research | Josh Billings, MD, MSCI Charles Bernard Pittinger Prize-Health Services and Informatics Research | Jon Wanderer, MD, MPhil Best Oral Presentation | Loren Smith, MD, PhD Best Poster Presentation | Sujay Kharade, PhD Best Poster Presentation | Brandon Turner Roger England Research Award for Excellence in Support of Basic and Clinical Science | Travis Spain Loren Smith, MD, PhD; Travis Spain; Susan Eagle, MD; Josh Billings, MD, MSCI; Brad Grueter, PhD; Sujay Kharade, PhD; Brandon Turner (PhD candidate)

The major focus of the Basic Science Research Division is the study of the physiology, pharmacology, and cell biology of ion channels, transporters, and receptors.

Multiple projects by investigators are sponsored by the National Institutes of Health. Work within the Research Division and core investigators include: Dr. Frederic T. (Josh) Billings, IV, Assistant Professor of Anesthesiology, is focusing on mechanisms of surgeryinduced organ injury, specifically the impact of perioperative oxidative damage to kidney, brain, and heart, and developing new therapy for perioperative organ injury in humans.

Dr. Stephen Bruehl, Professor of Anesthesiology, has identified pain-

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related alterations in interacting cardiovascular-pain modulatory systems that contribute to enhanced pain responsiveness.

Dr. Kevin Currie, Associate Professor of Anesthesiology & Pharmacology, is currently investigating G proteincoupled receptors (including opioid and prostanoid receptors) and the serotonin transporter (an important target for antidepressants) control catecholamine secretion and the sympathoadrenal stress response.

Dr. Eric Delpire, Professor and Chief of the Basic Science Research Division, utilizes genetically-modified mouse models and a variety of molecular techniques to investigate how neuronal Cl- transporters modulate inhibitory synaptic transmission and how renal

The Bradley Smith Mentorship Award | Susan Eagle, MD

Na+ transporters and associated proteins regulate salt reabsorption and blood pressure. The laboratory utilizes high throughput screening and protein modeling to identify novel compounds/ drugs that target these transporters and regulators.

Dr. Jerod Denton, Associate Professor of Anesthesiology & Pharmacology Division of Research, is doing earlystage drug discovery for a family of potassium channels involved in renal, endocrine, cardiac, and brain function. The goal is to develop sharp pharmacological tools for exploring the integrative physiology and, ultimately, druggability of these channels.

Drs. Brad and Carrie Grueter are researching the neurobiology of addiction and reward-related behaviors.

Dr. Matthias Riess is investigating the mechanisms of cardio- and neuroprotection following cardiac arrest, myocardial infarction and stroke in various translationally relevant cell, isolated organ and animal models.

Dr. Andrew Shaw, Executive Vice Chair, is researching common mechanistic factors leading to organ failure after cardiothoracic surgery.

Dr. Edward Sherwood, Professor and Vice Chair of Research, Dr. Julia Bohannon, Research Assistant Professor and Dr. Antonio Hernandez, Associate Professor, are studying several aspects of sepsis and burn injury and the application of immunotherapy in critically Ill patients.

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Advancing Technology to Improve Patient Care

Jesse Ehrenfeld, MD, MPH and Jonathan Wanderer, MD, MPhil

Brian Rothman, MD

VAPIR and Perioperative Informatics work beyond the walls of the operating room, advancing patient care through innovations in patient safety and quality. By integrating active research, state of the art technologies and clinical applications, VAPIR and Perioperative Informatics are advancing the frontiers of science and healthcare. Both have achieved measurable outcomes of success in patient care, infrastructure and educational programs.

Faculty members engage with students through mentorship and training programs, equipping the next generation of professionals. Vanderbilt Anesthesiology and Perioperative Informatics Research Division (VAPIR) VAPIR, led by Dr. Jonathan Wanderer, director and Dr. Jesse Ehrenfeld, associate director, is responsible for managing the Perioperative Data Warehouse (PDW), which contains full data from more than 880,000 procedures. The division collaborates internally and externally to strengthen its mission to improve patient care here and abroad. Students, residents and fellows can participate in seminars, journal clubs and a structured

summer research training program.

Experts in biomedical informatics and clinical research share their research at monthly seminars as visiting scholars. Among its many achievements, VAPIR has: • Created the informatics backbone that launched the Vanderbilt

Perioperative Surgical Home model of care delivery.

• Developed a suite of real-time data visualization tools, to enable clinicians to effortlessly view quality and performance metrics via automated email systems and online tracking dashboards.

• Enabled substantial reductions in surgical site infections and in institutional supply costs through cross-disciplinary collaborations.

Perioperative Informatics, led by Dr. Brian Rothman, designs, develops, and implements enhancements to Vanderbilt’s Perioperative Informa-

tion Management System (VPIMS).

Using health information technology solutions, the area supports best practice care and workflows to improve patient safety, care quality, efficiency, and communication through accurate and reliable real-time data acquisition and delivery.

Under Rothman’s leadership, Perioperative Informatics has implemented web-based solutions for situational awareness (SAGA), postoperative anesthesia note documentation (PAV), intraoperative decision support, and the case board (eORBoard), which is due for release very soon. Perioperative nursing now uses electronic checklists to support perioperative Enhanced Recovery After Surgery (ERAS) protocols that are reducing lengths of stay. Perioperative Informatic’s new Post Anesthesia Care Unit oriented case board was created in collaboration with bed management to deliver transparent, real time, patient status data for efficient enterprise-wide patient flow.

Other collaborations include Integrated Presence and Bedside Monitoring that are bringing perioperative, real-time monitoring and decision support to the ICUs and to surgical patients on general care floors.

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Shaping Tomorrow’s Leaders through Mentorship

Perioperative Clinical Research Institute

Edward Sherwood, MD, PhD, vice chair of Research and Pratik Pandharipande, MD, MSCI, division chief of Critical Care

The VACRAC (Vanderbilt Anesthesiology Clinical Research Advisory Committee), in partnership with the Perioperative Clinical Research Institute, supports new investigators in developing clinical research projects that will lead to publication and, if possible, extramural funding. The committee oversees the development and conduct of industry-sponsored and investigator-initiated research by developing and managing essential research services and programs.

The committee: • Mentors potential investigators throughout the research development process.

• Creates opportunities for ongoing learning about research methods, proposal writing, IRB applications, data management and analysis, and presentation/publication skills.

• Reviews new research proposals and regularly audits ongoing investigations for effectiveness and compliance with regulatory and safety guidelines.

VACRAC members are Edward Sherwood, MD, PhD (chair); Pratik Pandharipande, MD, MSCI (co-chair); Matt Shotwell, PhD (co-chair); Josh Billings, MD, MSCI; Brian Donahue, MD, PhD; Matthew McEvoy, MD; Damon Michaels;

The Perioperative Clinical Research Institute (PCRI) is led

by Edward Sherwood, MD, PhD, and Damon Michaels.

The division provides a full range of support services, including regulatory management, data management, contracts management, biostatistics, biomedical informatics, and financial oversight. The group also trains new investigators so they achieve their own funded research that leads to major publications. The

end goal is stronger clinical research, with an eye toward publication in leading journals and changing practice.

Clinical research within the department includes both industry-sponsored and investigator-initiated clinical projects and focuses on the advancement of medical practice in the fields of perioperative care, chronic pain, and medical devices. Most of the department’s investigators are practicing physicians who use their clinical expertise to de-

velop research protocols that seek to answer clinically significant questions.

The PCRI oversees more than 114 active clinical trials, with many more studies in development. The team consists of highly trained and broadly experienced research professionals, including five research nurses, one research assistant, one clinical trials associate, one senior clinical trials associate, one senior regulatory specialist, and one administrative assistant.

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Center for Research and Innovation in Systems Safety

VUMC’s Center for Research and Innovation in Systems Safety (CRISS), directed by Matthew B. Weinger, MD, is an institution-wide resource for human factors, usability, and systems engineering and design, located within the Department of Anesthe-

siology. CRISS is an integral part of Vanderbilt’s Institute for Medicine and Public Health (IMPH), led by Robert Dittus, MD, MPH. CRISS consists of anesthesiologists and PhD researchers who conduct

basic and applied research in healthcare informatics, patient safety, and clinical quality; design, assess, and improve care processes, medical technology and electronic health record (EHR) user interfaces; and utilize stateof-the-art simulation facilities to test and analyze medical equipment and procedures.

CRISS has other faculty and collaborators across Health Sciences and in the School of Engineering.

CRISS involvement with VUMC operational initiatives in quality improvement range from participating in the review and analysis of serious clinical

events to re-engineering blood transfusion processes, improving clinician handovers, and enhancing compliance with perioperative timeouts and checklists.

CRISS faculty and staff are integrally involved in user interface design and evaluation for VUMC’s Health IT program. CRISS is helping design several Vanderbilt Perioperative Information Management System (VPIMS) modules. CRISS conducts formal usability testing of VUMC software applications under development and of medical devices being considered for purchase.

Research Faculty and Staff

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Key Clinical Research Studies Bret Alvis, MD: Continuous Supraglottic pH Monitoring in Prolonged Intubated Intensive Care Patients and High Risk Aspiration Intraoperative Patients Curtis Baysinger, MD: Effects of Tadalafil (Cialis), a Long-acting PDE5 Inhibitor, on the Human Fetoplacental Microcirculation: A Study Using the in Vitro, Dual-perfused, Single-isolated Cotyledon, Human Placental Model Claudia Benkwitz, MD, PhD: Validation of the FORE-SIGHT Elite Tissue Oximeter in Pediatric Subjects for Cerebral and Somatic Applications Frederic T. Billings, MD: The Effect of Maintaining Physiologic Oxygenation on Oxidative Stress During Cardiac Surgery The Effect of Short-term Atorvastatin Use on Acute Kidney Injury Following Cardiac Surgery A Phase II Multicenter, Parallel-group, Randomized, Double-blind, Proof-ofConcept, Adaptive Study Investigating the Safety and Efficacy of THR-184 Administered via Intravenous Infusion in Patients at Increased Risk of Developing Cardiac Surgery Associated-Acute Kidney Injury (CSA-AKI) James L. Blair, DO: Does Continuous Perioperative Dexmedetomidine Infusion Reduce Time to Discharge in Patients Undergoing Major Lumbar Fusion? A Double-blind, Placebo-controlled Study Peri-anesthetic Imaging of Cognitive Decline (PAICOD) – A Prospective Pilot Study Clifford Bowens, MD: Comparison of Perineural Catheter Depth for the Continuous Popliteal Nerve Block Using Ultrasound Guidance and Dermabond Jill Boyle, MD: Inhaled Nitrous Oxide for Labor: A Prospective, Randomized, Double-Blind Trial

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Nathan Brummel, MD: ACT-ICU: Activity and Cognitive Therapy in the Intensive Care Unit Christopher Canlas, MD: Perioperative Pulse Oximetry in Obstructive Sleep Apnea Patients in the Ambulatory Setting Elizabeth Card, MSN, APRN, FNP-BC: Prevalence of Delirium in the Post Anesthesia Care Unit A Randomized controlled trail of 2% chlorhexidine gluconate skin preparation cloths for the prevention of post op surgical site infections in spine patients “A Survey Evaluating Burnout, Depression, Alcohol and Substance Use, and Social Support Among ASPAN members” Michael Chi, MD: Reducing Serious Peripheral Intravenous Catheter Infiltrations Intraoperatively with Electronic Reminders Katherine Dobie, MD: Ultrasound-guided Isolation and Blockade of the Upper Trunk for Shoulder Surgery: Time to Replace the Traditional Interscalene Approach?

Susan Eagle, MD: Measurement of the Pressures at Which Intravenous Fluids are Electromechanically Infused Non-invasive device to compare peripheral venous pressure with standard invasive monitoring during resuscitation of hemorrhagic shock Jesse M. Ehrenfeld, MD, MPH: Dynamic Data Visualization of Deidentified Data as a Clinical Support Tool Usability of Novel Patient Data Visualizations Using Department of Defense and Civilian Medical Treatment Facility Data Defining the Impact of Patients with High Utilization of Healthcare Services Propofol, Race, and Ethnicity: Examining current dosing practices and their effects on patient outcomes

Risk Factors for Carotid Artery Puncture During Central Line Placement

Health Literacy and Perioperative Outcomes

Exploring the impact of hypokalemia on surgical and perioperative outcomes

Normothermia and The Risk of Surgical Site Infection

Intraoperative Medications Associated with Clinically Significant Anaphylaxis

Awareness of Risk of Acute Lung Injury

Genomics and Perioperative Medicine Risk Factors for Postoperative Pneumonia Preoperative Laboratory Testing External validation of the Risk Quantification Index Using Natural Language Processing to Identify LGBTI Patients in the VUMC EMR and determine how LGBTI status affects diagnosis, treatment, and health outcomes Does Use of Non-depolarizing Neuromuscular Blocking Agents Predict Postoperative Respiratory Complications

Analysis of Operating Room Video Feed A Retrospective Study Examining Progression of Anesthesia Resident’s Skills United States Critical Illness and Injury Trials Group (USCIITG) Informatics Working Group (IWG) Multicenter Performance Site (MPS) Central Line Placement Under Ultrasound: Is Routine Chest X-ray Warranted?

Effect of A Novel Electronic Blood Ordering System on Patient Outcomes Conscious Sedation Management with Mixed Patient Simulators

Impact of Vigilance / VigiVu on Perioperative Throughput

Preoperative Hyperglycemia in Undiagnosed Diabetics

Impact of Centralized Bed Management on OR Throughout

Role of B Blockers in Stroke after Non-cardiac Surgery: An Observational Study from the Multicenter Perioperative Outcomes Group

Impact of Attending Surgical Case Coverage on Perioperative Outcomes Impact of On Time OR Starts on Workflow Perceptions Incidence of Hypoxemia During Surgery & Anesthesia Central line-associated bloodstream infections after landmark versus ultrasound guided placement Prevalence of Red-Green Colorblind Healthcare Providers: A Pilot Study Evaluation of Mobile Clinical Information System on Surgical Workflow Impact of Diabetes Quality Improvement Protocol

Utility of the Surgical Apgar Score on Postoperative Outcomes in Pediatrics Leslie Fowler, MEd: Ongoing Professional Performance Evaluation (OPPE) Using ACGME Six Core Competencies for Anesthesiology Residents Anesthesiology Residency Program Testing Policy Survey Andrew Franklin, MD:A Phase IV Study to Evaluate the Pharmacokinetics and Safety of Oxycodone Oral Solution in Pediatric and Adolescent Subjects Stephen R. Hays, MD: An evaluation of the efficacy and safety of tapentadol oral solution in the treatment of post-operative

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acute pain requiring opioid treatment in pediatric subjects aged from birth to less than 18 years old.

A Randomized, Placebo Controlled, Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Intravenous (IV) Acetaminophen for the Treatment of Acute Pain in Pediatric Patients Multicenter Study of the Safety, Tolerability, Effectiveness, and Pharmacokinetics of Oxymorphone HCl Extended-Release Tablets in Pediatric Subjects Requiring an Around-the-Clock Opioid for an Extended Period of Time Multisite RCT Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants Open-label, Non-randomized, Multicenter, Ascending Dose by Age, Single- and Multiple-dose Evaluation of the Effectiveness, Safety, and Tolerability of Oral Liquid Oxymorphone HCl Immediate-release Oral Liquid for Acute Postoperative Pain in Pediatric Subjects Pediatric Anesthesia NeuroDevelopment Assessment Study (PANDAS) Patrick Henson, DO: Study Evaluating the Expression of Effectors of Immune Tolerance and Associated Infectious Outcomes in Burn Patients Antonio Hernandez, MD: Comparison of Endotracheal Intubation Over the Aintree via the I-gel and Laryngeal Mask Airway Supreme Douglas Hester, MD: Cost Containment of Anesthetic-related Intra-operative Costs King Vision Video Laryngoscope vs.

Glidescope Video Laryngoscope: A Comparative Study in Ambulatory Surgery Center Patients Michael Higgins, MD: Nasopharyngeal versus Nasal Cannula Oxygen

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Supplementation in Oral Surgery Patients Marc Huntoon, MD: Controlled, Two-arm, Parallel Group, Randomized Withdrawal Study to Assess the Safety and Efficacy of Hydromorphone Hydrochloride Delivered

by Intrathecal Administration Using a Programmable Implantable Pump Phase 3, Open-Label, Single-Arm Study To Assess The Safety Of Hydromorphone Hydrochloride Delivered By Intrathecal Administration Steve Klintworth, RN: A Randomized Controlled Trial of 2% Chlorhexidine Gluconate Skin Preparation Cloths for the Prevention of Post-Operative Surgical Site Infections in Colorectal Patients Avinash Kumar, MD: Risk Factors for New Onset Acute Kidney Injury Following Aneurysmal Subarachnoid Hemorrhage: A Single-center Retrospective Cohort Study.

A study comparing the results of a “question of the day” module with MCCKAP scores Lorri Lee, MD: Moyamoya in Non-Asian North Americans Letha Mathews, MBBS: The Effects of Dexmedetomidine and Remifentanil on Microelectrode Recordings During Deep Brain Stimulation Surgery: A Retrospective Analysis of the Vanderbilt Experience Radiographically Measured Neck Motion During Intubation with MILS by Two Different Video Laryngoscopes Matthew McEvoy, MD: Enhanced Recovery After Surgery in Colorectal Surgery: A Large-Scale Quality I mprovement Project Assessment of Intraoperative Temperature and Postoperative Delirium in the HIPEC Surgical Population Effect of a Cognitive Aid on Adherence to the American Society of Regional Anesthesia Guidelines for Management of Patients on Anticoagulation

Assessing the Reliability of Applicant Commitment Statements and How They Correlate to a Successful Match

Informed Consent Conversations

Teaching CA-1 Anesthesia Residents by “Flipping the Classroom” Improves Knowledge Acquisition and Resident Satisfaction

A Retrospective Review “Take-Back” Surgeries in a Large Academic Center

Kelly McQueen, MD, MPH: Determining the Perioperative Mortality Rate in Low-income Countries

Perioperative Type and Screen: Utilization Patterns and Clinical Decision Support Performance

Impacting the Global Trauma Crisis: Pilot Study in Mozambique

Prediction of Airway Management Difficulty from Patient Photographs

The Global Burden of Pain Evaluation Proposal

Perioperative Management and Neurological Outcomes for Thoracic and Thoracoabdominal Aortic Stent Grafting: A Case Series

Thanh Nguyen, MD: Pediatric Craniofacial Surgery Perioperative Registry (PCSPR) What is the Prevalence of Vitamin D Deficiency Among Children Undergoing Posterior Spinal Fusion?

Brian O’Hara, MD: Procedures and Outcomes of Airway Management

Monitoring and Improving Resident Duty Hours

Prediction models for acute lung injury

Impact of GasChart Notifications on Anesthesia Provider Behavior Vanderbilt Anemia Management Program for Preoperative Intervention, Research and Education: A Feasibility Study

A Survey Assessing the Comfort Level of Residents in Performing Emergency Airway Techniques, Cricothyrotomy, and Thoracoscopy Before and After ATLS Training

Development and Validation of Prediction Models for Hospital Morbidity and Mortality

Edward Sherwood, MD, PhD: Baseline Quantitative Neuromuscular Monitoring in the PACU

Evaluation of Electronic Screening Tools for Preoperative Assessment Perioperative Outcomes Awareness Project

The Impact of Quantitative Neuromuscular Monitoring in the PACU on Residual Blockade and Postoperative Recovery

Quantification of Variability in Anesthesia Residency Training

A Study Evaluating Gene Expression Response to TLR4 Agonists Chad Edward Wagner, MD: Multicenter Retrospective hTEE Review

Evaluation of Electronic Screening Tools for Functional Status Assessment

The Electronic Medical Record Habits of Highly Effective Anesthesia Residents The Use of Electronic Pre-operative Notes

Delirium and pain in the postoperative cardiac surgery patient: a retrospective review

Sheena Weaver, MD: Characterizing Palliative Care Presence in Acute Stroke Patients Admitted to the Neurological & Neurosurgical ICU

Jonathan P. Wanderer, MD, MPhil: Evaluation of ACS NSQIP Surgical Risk Calculator Implementation in Preoperative

Liza Weavind, MB BCh: Does Anemia Contribute to End-organ Dysfunction in ICU Patients?

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Advancing Medical Education through Endowments Special Lectureships & Awards The department hosts special lectureships throughout the year and presents distinct recognitions to department members who have provided exemplary service to both their patients and colleagues.

Jerod Denton, PhD

Josh BIllings, MD, MSCI

Many of these are a direct result of philanthropic support from our alumni, as well as from current department members and other program supporters. Funding is provided by private donors, whose gifts materially improve the academic life of the Vanderbilt Department of Anesthesiology.

The Benjamin Howard Robbins Scholar Program began in 2007 to support the professional development of young clinician-scientists within the department. Building critical research skills under the mentorship of an established scientist helps prepare young investigators to eventually establish a vigorous, independently funded research program. The program is named in honor of the the department’s first chairman, himself a renowned physician-scientist.

The BH Robbins Scholar Program is multidisciplinary, encouraging and supporting mentorships and collaborations that extend far beyond the traditional boundaries of anesthesia.

“This program provides a unique mentored research experience for young scholars that culminates in a two-year multidisciplinary fellowship, with at least one year devoted to research,” said Department Chair Warren Sandberg, MD, PhD.

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“Our Robbins scholars benefit from one-onone mentorship, a wealth of research and educational resources, protected research time, and a stipend during their residency and fellowship.”

Adam Kingeter, MD, Michael Chi, MD, Joseph Schlesinger, MD, Marcos Lopez, MD, Frederic T. (Josh) Billings, MD, MSCI

The BH Robbins Scholar Program is co-directed by Jerod Denton, PhD, and Frederic T. (Josh) Billings, IV, MD, MSCI. Current scholars include: Adam Kingeter, MD, (Scholar 2013-2019), developed a charge dashboard in collaboration with the VUMC Department of Finance that allows for the real-time tracking of expenses on any patient admitted to an intensive care unit. He is mentored by Chief of Staff of Vanderbilt University Hospital C. Lee Parmley, MD, JD, as well as members of the Department of Health Policy.

Marc Lopez, MD, MSCI, (Scholar 20142019), investigating the impact of intraoperative oxidative stress on postoperative endothelial dysfunction in patients randomized to hyperoxia or normoxia during cardiac surgery. Dr. Lopez is mentored by Josh Billings, MD, MSCI. Joseph Schlesinger, MD, (Scholar 2011-2016), examining multisensory perceptual training, specifically improving unisensory pulse oximetry pitch perception and attentional load processing. Dr.

Schlesinger is mentored by Mark Wallace, PhD, Director of the Vanderbilt Brain Institute, and Matthew Weinger, MD. Schlesinger has presented his work at the American Society of Anesthesiologists, the Society for Neuroscience, the American Society of Critical Care Anesthesiologists, and the American Medical Association. His original research articles have been published in Anesthesiology and Anesthesia & Analgesia.

Michael Chi, MD, (Scholar 2015-2019), studying the application of reactive oxygen species (ROS)-responsive microspheres for on demand anti-inflammatory therapy of neuropathic pain. Dr. Chi is mentored by Craig Duvall, PhD, Jerod Denton, PhD, Ronald Wiley, MD, PhD, and Edward Sherwood, MD, PhD. Heidi Smith, MD, MSCI, a BH Robbins Scholar (2011-2016) and assistant professor of Anesthesiology, is the principal investigator of groundbreaking research on pediatric delirium. The initiative monitors children hospitalized in Pediatric Critical Care Units (PCCUs) for delirium. Dr. Smith is mentored by Pratik

Pandharipande, MD, MSCI

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Special Lectureships & Awards cont’d.

Dr. James Phythyon Endowed Lectureship in Pediatric Anesthesiology The lectureship was established by the family of Dr. James Phythyon, a founding member of the Pediatric Anesthesiology Division. Dr. Phythyon’s widow, Mrs. Marlin Sanders, and the couple’s daughters, Mary Neal Meador, Elizabeth Donner, and Sarah Miller, are strong supporters of the department.

The Sandidge Pediatric Pain Management Endowed Fund Retired Vanderbilt anesthesiologist Paula C. Sandidge, MD, created The Sandidge Pediatric Pain Management Endowed Fund at Monroe Carell Jr. Children’s Hospital at Vanderbilt in 2010 to recognize and encourage progress in pain management for children.

The Dila Vuksanaj Memorial Fund for Resident Education Pediatric anesthesiologist Dila Vuksanaj, MD, practiced at Children’s Hospital for 13 years, dedicating herself to her patients and to the hundreds of trainees who looked to her as a role model, mentor, and friend. Following her death in 2009, her family, including her husband Jacques Heibig, MD, founded the Dila Vuksanaj Memorial Fund for Resident Education.

Dr. Bradley E. Smith Endowed Lectureship on Medical Professionalism Former chairman Bradley E. Smith, MD, defined what it means to be a true professional, and in 2009 a lectureship on medical professionalism was established in his name by then Department Chairman Michael Higgins, MD. The goal of the lectureship is to reflect on the characteristics, responsibilities, and rewards of professionalism as applied to the practice of anesthesiology.

Dr. Charles Beattie Endowed Lectureship Established by Dr. Warren Sandberg, the lectureship is intended to bring innovators in anesthesiology from unique backgrounds and compelling world views to Vanderbilt as visiting professors.

We’ve developed tools to assess for delirium on a daily basis.”

“

Dr. Heidi Smith, Pediatric Anesthesiology 33

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Selected Publications, 2015-2016 Peer-reviewed Original and Review Articles Aline F, Wanderer JP, Ehrenfeld JM: Managing the Impact of the ICD-10 Transition on a Data Warehouse. J Med Syst 2016; 40:57 Alvis BD, Hughes CG: Physiology Considerations in Geriatric Patients. Anesthesiol Clin 2015; 33:447-56 Baldi R, Ghosh D, Grueter BA, Patel S: Electrophysiological Measurement of Cannabinoid-Mediated Synaptic Modulation in Acute Mouse Brain Slices. Curr Protoc Neurosci 2016; 75:6 29 1-6 19 Bane CE, Jr., Ivanov I, Matafonov A, Boyd KL, Cheng Q, Sherwood ER, Tucker EI, Smiley ST, McCarty OJ, Gruber A, Gailani D: Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice. PLoS One 2016; 11:e0152968 Banerjee A: Using Simulation for Primary Certification. Int Anesthesiol Clin 2015; 53:42-59 Basher S, Bick J, Maltais S: Back table outflow graft anastomosis technique for HeartWare HVAD implantation. J Cardiovasc Surg (Torino) 2015; 56:945-8 Beazley B, Bulka CM, Landsman IS, Ehrenfeld JM: Demographic Predictors of NPO Violations in Elective Pediatric Surgery. J Perianesth Nurs 2016; 31:36-40 Berry JM: My Postop Visit. Anesthesiology 2016 Mar [Epub] Beyenbach KW, Yu Y, Piermarini PM, Denton J: Targeting renal epithelial channels for the control of insect vectors. Tissue Barriers 2015; 3:e1081861 Billings FTt, Hendricks PA, Schildcrout JS, Shi Y, Petracek MR, Byrne JG, Brown NJ: HighDose Perioperative Atorvastatin and Acute Kidney Injury Following Cardiac Surgery: A Randomized Clinical Trial. JAMA 2016; 315:877-88 Bohannon JK, Luan L, Hernandez A, Afzal A, Guo Y, Patil NK, Fensterheim B, Sherwood ER: Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil

functions after burn injury. J Leukoc Biol 2016; 99:629-40 Booth GS, Pilla MA: Preventing the preventable: How the blood bank laboratory information system fails to protect patients that refuse blood. Transfus Apher Sci 2016 Apr [Epub} Boyer RB, Hocking KM, Booth GS, Berry JM, Spain TW, Michaels DR, Sandberg WS, Pilla MA: An Evaluation of Induced Failure Modes in the Belmont® Rapid Infuser. Anesth Analg 2016; 122:1062-9 Bruehl S, Burns JW, Gupta R, Buvanendran A, Chont M, Orlowska D, Schuster E, France CR: Do Resting Plasma Beta-Endorphin Levels Predict Responses to Opioid Analgesics? Clin J Pain 2016 May [Epub] Bruehl S, Maihofner C, Stanton-Hicks M, Perez RS, Vatine JJ, Brunner F, Birklein F, Schlereth T, Mackey S, Mailis-Gagnon A, Livshitz A, Harden RN: Complex regional pain syndrome: evidence for warm and cold subtypes in a large prospective clinical sample.

Pain 2016; 157:1674-81 Bruehl S: Complex regional pain syndrome.

BMJ 2015; 351:h2730 Bucher BT, Duggan EM, Grubb PH, France DJ, Lally KP, Blakely ML: Does the American College of Surgeons National Surgical Quality Improvement Program pediatric provide actionable quality improvement data for surgical neonates? J Pediatr Surg 2016 Apr [Epub] Buchheit T, Van de Ven T, Hsia HL, McDuffie M, MacLeod DB, White W, Chamessian A, Keefe FJ, Buckenmaier CT, Shaw AD: Pain Phenotypes and Associated Clinical Risk Factors Following Traumatic Amputation: Results from Veterans Integrated Pain Evaluation Research (VIPER). Pain Med 2016; 17:149-61 Burns JW, Gerhart JI, Bruehl S, Post KM, Smith DA, Porter LS, Schuster E, Buvanendran A, Fras AM, Keefe FJ: Anger arousal and behavioral anger regulation in everyday life among people with chronic low back pain: Relationships with spouse responses and negative affect. Health Psychol 2016; 35:29-40 Carayon P, Weinger MB, Brown R, Cartmill RS, Slagle J, Van Roy KS, Walker JM, Wood

KE: How Do Residents Spend Their Time in the Intensive Care Unit? Am J Med Sci 2015; 350:403-8

Delpire E: Research antibodies: do not use them to stain your reputation. Am J Physiol Cell Physiol 2015; 309:C707-8

Chang MP, Lyon CB, Janiszewski D, Aksamit D, Kateh F, Sampson J: Evaluation of a cardiopulmonary resuscitation curriculum in a low resource environment. Int J Med Educ 2015; 6:136-41

Delpire E: STIM and Orai Proteins in Calcium Signaling: an AJP-Cell Physiology series of Themed Reviews. Am J Physiol Cell Physiol 2016; 310:C401

Choi L, Ferrell BA, Vasilevskis EE, Pandharipande PP, Heltsley R, Ely EW, Stein CM, Girard TD: Population Pharmacokinetics of Fentanyl in the Critically Ill. Crit Care Med 2016; 44:64-72 Craig BT, Rellinger EJ, Mettler BA, Watkins S, Donahue BS, Chung DH: Laparoscopic Nissen fundoplication in infants with hypoplastic left heart syndrome. J Pediatr Surg 2016; 51:76-80 Cropsey C, Kennedy J, Han J, Pandharipande P: Cognitive Dysfunction, Delirium, and Stroke in Cardiac Surgery Patients. Semin Cardiothorac Vasc Anesth 2015; 19:309-17 Davidson AJ, Disma N, de Graaff JC, Withington DE, Dorris L, Bell G, Stargatt R, Bellinger DC, Schuster T, Arnup SJ, Hardy P, Hunt RW, Takagi MJ, Giribaldi G, Hartmann PL, Salvo I, Morton NS, von Ungern Sternberg BS, Locatelli BG, Wilton N, Lynn A, Thomas JJ, Polaner D, Bagshaw O, Szmuk P, Absalom AR, Frawley G, Berde C, Ormond GD, Marmor J, McCann ME, GAS consortium: Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial. Lancet 2016; 387:239-50 (Stephen Hays is a G.A.S. consortium member) Davidson AJ, Morton NS, Arnup SJ, de Graaff JC, Disma N, Withington DE, Frawley G, Hunt RW, Hardy P, Khotcholava M, von Ungern Sternberg BS, Wilton N, Tuo P, Salvo I, Ormond G, Stargatt R, Locatelli BG, McCann ME, General Anesthesia compared to Spinal anesthesia (GAS) Consortium: Apnea after Awake Regional and General Anesthesia in Infants: The General Anesthesia Compared to Spinal Anesthesia Study--Comparing Apnea and Neurodevelopmental Outcomes, a Randomized Controlled Trial. Anesthesiology 2015; 123:38-54 (Stephen Hays is a G.A.S. consortium member)

DiMiceli-Zsigmond M, Williams AK, Richardson MG: Expecting the Unexpected: Perspectives on Stillbirth and Late Termination of Pregnancy for Fetal Anomalies. Anesth Analg 2015; 121:457-64 Dobie KH, Tiwari V, Sandberg WS: “What Have We Done for Us Lately?”--Defining Performance and Value at the Individual Clinician Level. Anesthesiol Clin 2015; 33:659-77 Donald C, Ehrenfeld JM: The Opportunity for Medical Systems to Reduce Health Disparities Among Lesbian, Gay, Bisexual, Transgender and Intersex Patients. J Med Syst 2015; 39:178 Downing JW, Baysinger CL: Oxygenating laryngoscopy. Anaesthesia 2016; 71:727-8 Dugas AF, Kirsch TD, Toerper M, Korley F, Yenokyan G, France D, Hager D, Levin S: An Electronic Emergency Triage System to Improve Patient Distribution by Critical Outcomes. J Emerg Med 2016; 50:910-8 Easdown LJ, Moore DE, Jr.: Maintaining Professional Excellence in Contemporary Anesthesia Practice. Int Anesthesiol Clin 2016; 54:170-87 Efird JT, Griffin WF, Davies SW, O’Neal WT, Crane PB, Kindell LC, O’Neal JB, Chitwood WR, Jr., Kypson AP: Seasonal Incidence of Emergent Coronary Artery Bypass Grafting Surgery. Heart Surg Forum 2016; 19:E048-53 Efird JT, Gudimella P, O’Neal WT, Griffin WF, Landrine H, Kindell LC, Davies SW, Sarpong DF, O’Neal JB, Crane P, Nelson MA, Ferguson TB, Chitwood WR, Kypson AP, Anderson EJ: Comparison of Risk of Atrial Fibrillation in Black Versus White Patients After Coronary Artery Bypass Grafting. Am J Cardiol 2016; 117:1095-1100 Enkhbaatar P, Nelson C, Salsbury JR, Carmical JR, Torres KE, Herndon D, Prough DS, Luan L,

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Sherwood ER: Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysaccharide and Monophosphoryl Lipid A. PLoS One 2015; 10:e0144345 France CR, Burns JW, Gupta RK, Buvanendran A, Chont M, Schuster E, Orlowska D, Bruehl S: Expectancy Effects on Conditioned Pain Modulation Are Not Influenced by Naloxone or Morphine. Ann Behav Med 2016; 50:497-505 France DJ, Levin S, Ding R, Hemphill R, Han J, Russ S, Aronsky D, Weinger M: Factors Influencing Time-Dependent Quality Indicators for Patients With Suspected Acute Coronary Syndrome. J Patient Saf 2016 Jan [Epub] Franklin AD, Hughes EM: Fluoroscopically guided tunneled trans-caudal epidural catheter technique for opioid-free neonatal epidural analgesia. J Anesth 2016; 30:493-7 Frawley G, Bell G, Disma N, Withington DE, de Graaff JC, Morton NS, McCann ME, Arnup SJ, Bagshaw O, Wolfler A, Bellinger D, Davidson AJ, General Anesthesia compared to Spinal anesthesia (GAS) Consortium: Predictors of Failure of Awake Regional Anesthesia for Neonatal Hernia Repair: Data from the General Anesthesia Compared to Spinal Anesthesia Study--Comparing Apnea and Neurodevelopmental Outcomes. Anesthesiology 2015; 123:55-65 (Stephen Hays is a G.A.S. consortium member) Galvez JA, Rothman BS, Doyle CA, Morgan S, Simpao AF, Rehman MA: A Narrative Review of Meaningful Use and Anesthesia Information Management Systems. Anesth Analg 2015; 121:693-706 Gamboa JL, Billings FTt, Bojanowski MT, Gilliam LA, Yu C, Roshanravan B, Roberts LJ, 2nd, Himmelfarb J, Ikizler TA, Brown NJ: Mitochondrial dysfunction and oxidative stress in patients with chronic kidney disease. Physiol Rep 2016; 4:e12780 Gamboa JL, Pretorius M, Sprinkel KC, Brown NJ, Ikizler TA: Angiotensin converting enzyme inhibition increases ADMA concentration in patients on maintenance hemodialysis--a randomized cross-over study. BMC Nephrol 2015; 16:167 Greenberg SE, VanHouten JP, Lakomkin N, Ehrenfeld J, Jahangir AA, Boyce RH, Obremksey WT, Sethi MK: Does Admission to Medicine or Orthopaedics Impact a Geriatric Hip Patient’s Hospital Length of Stay? J Orthop

Trauma 2016; 30:95-9 Gruss C, Terekhov MA, Ehrenfeld JM, Kunic RJ, Wanderer JP: Estimating virtual neck circumference for preoperative STOP-BANG assessment: a retrospective cohort study. Can J Anaesth 2016; 63:120-2 Gunnerson KJ, Shaw AD, Chawla LS, Bihorac A, Al-Khafaji A, Kashani K, Lissauer M, Shi J, Walker MG, Kellum JA, Sapphire Topaz i: TIMP2*IGFBP7 biomarker panel accurately predicts acute kidney injury in high-risk surgical patients. J Trauma Acute Care Surg 2016; 80:243-9 Guo Y, Luan L, Rabacal W, Bohannon JK, Fensterheim BA, Hernandez A, Sherwood ER: IL-15 Superagonist-Mediated Immunotoxicity: Role of NK Cells and IFN-gamma. J Immunol 2015; 195:2353-64 Gupta RK, McEvoy MD: Initial Experience of the American Society of Regional Anesthesia and Pain Medicine Coags Regional Smartphone Application: A Novel Report of Global Distribution and Clinical Usage of an Electronic Decision Support Tool to Enhance Guideline Use. Reg Anesth Pain Med 2016; 41:334-8 Hand WR, Stoll WD, McEvoy MD, McSwain JR, Sealy CD, Skoner JM, Hornig JD, Tennant PA, Wolf B, Day TA: Intraoperative goal-directed hemodynamic management in free tissue transfer for head and neck cancer. Head Neck 2016; 38 Suppl 1:E1974-80 Hanks CA, Weinger MB: Know Yourself, Know the System: Developing a Successful Career and Being Promoted as an Academic Anesthesiologist. Int Anesthesiol Clin 2016; 54:155-69 Hanna GM, Fishman I, Edwards DA, Shen S, Kram C, Liu X, Shotwell M, Gilligan C: Development and Patient Satisfaction of a New Telemedicine Service for Pain Management at Massachusetts General Hospital to the Island of Martha’s Vineyard. Pain Med 2016 Apr [Epub] Hayhurst CJ, Durieux ME: Differential Opioid Tolerance and Opioid-induced Hyperalgesia: A Clinical Reality. Anesthesiology 2016; 124:483-8 Held JM, Litt J, Kennedy JD, McGrane S, Gunter OL, Rae L, Kahn SA: Surgeon-Performed Hemodynamic Transesophageal Echocardiography in the Burn Intensive Care Unit. J Burn Care Res 2016; 37:e63-8

Helwani MA, Saied NN: Automated pulse pressure variation display in the operating room and in the intensive care unit. J Clin Anesth 2015 Oct [Epub] Herington JL, Swale DR, Brown N, Shelton EL, Choi H, Williams CH, Hong CC, Paria BC, Denton JS, Reese J: High-Throughput Screening of Myometrial Calcium-Mobilization to Identify Modulators of Uterine Contractility.

PLoS One 2015; 10:e0143243 Hernandez A, Bohannon JK, Luan L, Fensterheim BA, Guo Y, Patil NK, McAdams C, Wang J, Sherwood ER: The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes. J Leukoc Biol 2016 Jun [Epub] Hernando D, Sharma SD, Aliyari Ghasabeh M, Alvis BD, Arora SS, Hamilton G, Pan L, Shaffer JM, Sofue K, Szeverenyi NM, Welch EB, Yuan Q, Bashir MR, Kamel IR, Rice MJ, Sirlin CB, Yokoo T, Reeder SB: Multisite, multivendor validation of the accuracy and reproducibility of proton-density fat-fraction quantification at 1.5T and 3T using a fat-water phantom. Magn Reson Med 2016 Apr [Epub] Hester DL, Ehrenfeld J: Anesthesia and sedation in the gastroenterology suite: leveraging clinical data to support operational workflows.

Techniques in Gastrointestinal Endoscopy 2016; 18:18-21 Hester DL: Lines Written on Viewing “Ether Day, 1846” in the Bullfinch Amphitheater.

Anesthesiology 2016; 124:1408-9 Hocking KM, Baudenbacher FJ, Sileshi B, Boyer RB, Kohorst KL, Brophy CM, Eagle SS: Peripheral Venous Waveform Analysis for Detecting Hemorrhage and Iatrogenic Volume Overload in a Porcine Model. Shock 2016 Apr [Epub] House LM, Calloway NH, Sandberg WS, Ehrenfeld JM: Prolonged patient emergence time among clinical anesthesia resident trainees. J Anaesthesiol Clin Pharmacol 2015

dysfunction during critical illness. Br J Anaesth 2015; 115:794-5 Hughes CG, Pandharipande PP, Thompson JL, Chandrasekhar R, Ware LB, Ely EW, Girard TD: Endothelial Activation and Blood-Brain Barrier Injury as Risk Factors for Delirium in Critically Ill Patients. Crit Care Med 2016 Apr [Epub] Itagaki T, Gubin TA, Sayal P, Jiang Y, Kacmarek RM, Anderson TA: The effectiveness of nasal mask vs face mask ventilation in anesthetized, apneic pediatric subjects over 2 years of age: a randomized controlled trial. Paediatr Anaesth 2016; 26:173-81 Jackson T, Thomas S, Stabile V, Han X, Shotwell M, McQueen KA: Chronic Pain Without Clear Etiology in Low- and Middle-Income Countries: A Narrative Review. Anesth Analg 2016; 122:2028-39 Jann JT, Edmiston EK, Ehrenfeld JM: Important Considerations for Addressing LGBT Health Care Competency. Am J Public Health 2015; 105:e8 Jering MZ, Marolen KN, Shotwell MS, Denton JN, Sandberg WS, Ehrenfeld JM: Combining the ASA Physical Classification System and Continuous Intraoperative Surgical Apgar Score Measurement in Predicting Postoperative Risk. J Med Syst 2015; 39:147 Jiang Y, Kacmarek RM: Efficacy of Superimposed High-frequency Jet Ventilation Applied to Variable Degrees of Tracheal Stenosis: One Step Forward to Optimized Patient Care.

Anesthesiology 2015; 123:747-9 Joffe ME, Grueter BA: Cocaine Experience Enhances Thalamo-Accumbens N-Methyl-D-Aspartate Receptor Function. Biol Psychiatry 2016 May [Epub] Joffe ME, Vitter SR, Grueter BA: GluN1 deletions in D1- and A2A-expressing cell types reveal distinct modes of behavioral regulation.

Neuropharmacology 2016 Mar [Epub]

House LM, Marolen KN, St Jacques PJ, McEvoy MD, Ehrenfeld JM: Surgical Apgar score is associated with myocardial injury after noncardiac surgery. J Clin Anesth 2016; 34:395-402

Johnson KB, Patterson BL, Ho YX, Chen Q, Nian H, Davison CL, Slagle J, Mulvaney SA: The feasibility of text reminders to improve medication adherence in adolescents with asthma. J Am Med Inform Assoc 2016; 23:44955

Hughes CG, Brummel NE, Girard TD, Graves AJ, Ely EW, Pandharipande PP: Change in endothelial vascular reactivity and acute brain

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R: Avoiding Adverse Events Secondary to Opioid-Induced Respiratory Depression: Implications for Nurse Executives and Patient Safety. J Nurs Adm 2016; 46:87-94 Kahle KT, Delpire E: Kinase-KCC2 coupling: Clrheostasis, disease susceptibility, therapeutic target. J Neurophysiol 2016; 115:8-18 Kahle KT, Khanna AR, Alper SL, Adragna NC, Lauf PK, Sun D, Delpire E: K-Cl cotransporters, cell volume homeostasis, and neurological disease. Trends Mol Med 2015; 21:513-23 Kahle KT, Khanna AR, Duan J, Staley KJ, Delpire E, Poduri A: The KCC2 Cotransporter and Human Epilepsy: Getting Excited About Inhibition. Neuroscientist 2016 May [Epub] Kamdar M, Edwards DA, Volney S, Rathmell J: A novel retrocrural approach for celiac plexus block: the single-needle retroaortic technique.

RAPM 2015; 40:610-615 Kharade SV, Flores D, Lindsley CW, Satlin LM, Denton JS: ROMK Inhibitor Actions in the Nephron Probed with Diuretics. Am J Physiol Renal Physiol 2015; 310:F732-F737

Kummerow Broman K, Phillips S, Hayes RM, Ehrenfeld JM, Holzman MD, Sharp K, Kripalani S, Poulose BK: Insurance status influences emergent designation in surgical transfers. J Surg Res 2016; 200:579-85 Ladha K, Vidal Melo MF, McLean DJ, Wanderer JP, Grabitz SD, Kurth T, Eikermann M: Intraoperative protective mechanical ventilation and risk of postoperative respiratory complications: hospital based registry study.

BMJ 2015; 351:h3646 Ladha KS, Wanderer JP, Nanji KC: Age as a predictor of rescue opioid administration immediately after the emergence of general anesthesia. J Clin Anesth 2015; 27:537-42 Latuska RF, Kuhl NO, Garrett CG, Berry JM, Gelbard A: Severe bradycardia associated with suspension laryngoscopy. Laryngoscope 2016; 126:949-50 Le HT, Hangiandreou N, Timmerman R, Rice MJ, Smith WB, Deitte L, Janelle GM: Imaging Artifacts in Echocardiography. Anesth Analg 2016; 122:633-46

Kharade SV, Nichols C, Denton JS: The shifting landscape of KATP channelopathies and the need for ‘sharper’ therapeutics. Future Med Chem 2016; 8:789-802

Lee H, Bach E, Noh J, Delpire E, Kandler K: Hyperpolarization-independent maturation and refinement of GABA/glycinergic connections in the auditory brain stem. J Neurophysiol 2016; 115:1170-82

Kla KM, Lee LA: Perioperative visual loss.

Best Pract Res Clin Anaesthesiol 2016; 30:6977

Lee LA, Mathews L: Anesthesia for Adults with Chronic Spinal Cord Injury. UpToDate 2016; Apr:Topic 104423 (Version 1.0)

Kla, KM, Lee, LA: Minimizing Complications in Major Spine Surgery. Current Anesthesiology Reports. 2016 Jun [Epub]

Levin MA, Wanderer JP, Ehrenfeld JM: Data, Big Data, and Metadata in Anesthesiology.

Anesth Analg 2015; 121:1661-7

Klonoff DC, Draznin B, Drincic A, Dungan K, Gianchandani R, Inzucchi SE, Nichols JH, Rice MJ, Seley JJ: PRIDE Statement on the Need for a Moratorium on the CMS Plan to Cite Hospitals for Performing Point-of-Care Capillary Blood Glucose Monitoring on Critically Ill Patients. J Clin Endocrinol Metab 2015; 100:3607-12

Lovvorn HN, 3rd, Pierce J, Libes J, Li B, Wei Q, Correa H, Gouffon J, Clark PE, Axt JR, Hansen E, Newton M, O’Neill JA, Jr., Kenyan Wilms Tumor C: Genetic and chromosomal alterations in Kenyan Wilms Tumor. Genes Chromosomes Cancer 2015; 54:702-15

Kougias P, Tiwari V, Berger DH: Use of simulation to assess a statistically driven surgical scheduling system. J Surg Res 2016; 201:306-12 Koumangoye R, Delpire E: The Ste20 kinases SPAK and OSR1 travel between cells through exosomes. Am J Physiol Cell Physiol 2016; 311:C43-53

Lyon C, Aksamit D, Janiszewski D, Kateh F, Chang M, Sampson J: Evaluation of Pediatric Mortality and Critical Care Capacity in Tappita, Liberia. Critical Care Medicine 2015; 43:86 Lyon CB, Merchant AI, Schwalbach T, Pinto EF, Jeque EC, McQueen KA: Anesthetic Care in Mozambique. Anesth Analg 2016; 122:16349 Mathews L, Lee LA: Anesthesia for Adults

with Acute Spinal Cord Injury. UpToDate 2016; Jan;Topic 91915 (Version 3.0) Mathieu V, Chantome A, Lefranc F, Cimmino A, Miklos W, Paulitschke V, Mohr T, Maddau L, Kornienko A, Berger W, Vandier C, Evidente A, Delpire E, Kiss R: Sphaeropsidin A shows promising activity against drug-resistant cancer cells by targeting regulatory volume increase. Cell Mol Life Sci 2015; 72:3731-46 McEvoy M, Nicochuk J, Ehrenfeld JM, Sandberg WS: Maintenance of Certification in Anesthesiology Part 4: Improvement in Medical Practice: Is It of Value and Where Do I Begin?

Advances in Anesthesia 2015; 33:157-73 McEvoy MD, DiLorenzo AN, Fowler LC, Schell RM: Faculty Development of Education Researchers in Academic Anesthesiology. Int Anesthesiol Clin 2016; 54:107-30 McEvoy MD, Hand WR, Stiegler MP, DiLorenzo AN, Ehrenfeld JM, Moran KR, Lekowski R, Nunnally ME, Manning EL, Shi Y, Shotwell MS, Gupta RK, Corey JM, Schell RM: A Smartphone-based Decision Support Tool Improves Test Performance Concerning Application of the Guidelines for Managing Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy. Anesthesiology 2016; 124:186-98 McEvoy MD, Wanderer JP, King AB, Geiger TM, Tiwari V, Terekhov M, Ehrenfeld JM, Furman WR, Lee LA, Sandberg WS: A perioperative consult service results in reduction in cost and length of stay for colorectal surgical patients: evidence from a healthcare redesign project. Perioper Med (Lond) 2016; 5:3 McGrane S, Smith HAB, Pandharipande P: Acute brain dysfunction during critical illness.

ICU Management 2015; 15:176-78 Merchant A, Calvo L, Outhay M, Sidat M, Lyon C, McQueen KAK: Basic ICU Capacity in the Province of Zambezia in Mozambique. Critical Care Medicine 2015; 43:83 Merchant A, Hendel S, Shockley R, Schlesinger J, Vansell H, McQueen K: Evaluating Progress in the Global Surgical Crisis: Contrasting Access to Emergency and Essential Surgery and Safe Anesthesia Around the World. World J Surg 2015; 39:2630-5 Miller A, Moon B, Anders S, Walden R, Brown S, Montella D: Integrating computerized clinical decision support systems into clinical work: A meta-synthesis of qualitative research. Int J

Med Inform 2015; 84:1009-18 Monroe TB, Gibson SJ, Bruehl SP, Gore JC, Dietrich MS, Newhouse P, Atalla S, Cowan RL: Contact heat sensitivity and reports of unpleasantness in communicative people with mild to moderate cognitive impairment in Alzheimer’s disease: a cross-sectional study.

BMC Med 2016; 14:74 Monroe TB, Gore JC, Bruehl SP, Benningfield MM, Dietrich MS, Chen LM, Newhouse P, Fillingim R, Chodkowski B, Atalla S, Arrieta J, Damon SM, Blackford JU, Cowan RL: Sex differences in psychophysical and neurophysiological responses to pain in older adults: a cross-sectional study. Biol Sex Differ 2015; 6:25 Monroe TB, Misra S, Habermann RC, Dietrich MS, Bruehl SP, Cowan RL, Newhouse PA, Simmons SF: Specific Physician Orders Improve Pain Detection and Pain Reports in Nursing Home Residents: Preliminary Data. Pain Manag Nurs 2015; 16:770-80 Morandi A, Brummel NE, Pandharipande P: Melatonin and the future of critically ill patients’ outcomes. Minerva Anestesiol 2015; 81:1277-9 Morey TE, Sappenfield JW, Gravenstein N, Rice MJ: Joint Commission and Regulatory Fatigue/Weakness/Overabundance/Distraction: Clinical Context Matters. Anesth Analg 2015; 121:394-6 Murphy M: Ten-Minute Miracle, Pulse, 2015 https://www.pulsevoices.org/index.php/ archive/stories/538-ten-minute-miracle.

Accessed 2016 Jul 30 Myler CS, Gupta RK: Spinal Anesthesia in a Patient With a History of Systemic Capillary Leak Syndrome (Clarkson Disease). Reg Anesth Pain Med 2015; 40:723-5 Nguyen TT, Hill S, Austin TM, Whitney GM, Wellons JC, 3rd, Lam HV: Use of blood-sparing surgical techniques and transfusion algorithms: association with decreased blood administration in children undergoing primary open craniosynostosis repair. J Neurosurg Pediatr 2015:556-63 Norman BC, Jackson JC, Graves JA, Girard TD, Pandharipande PP, Brummel NE, Wang L, Thompson JL, Chandrasekhar R, Ely EW: Employment Outcomes After Critical Illness: An Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychological

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Dysfunction in ICU Survivors Cohort. Crit Care Med 2016 May [Epub]

Considerations from a Pilot Study. J Parkinsons Dis 2015; 5:893-905

Correlate with Increased Reoperations for Complications. Am Surg 2015; 81:1177-81

O’Neal JB, Shaw AD: Goal-directed therapy in the operating room: is there any benefit? Curr Opin Anaesthesiol 2016; 29:80-4

Prielipp RC, Morell RC, Coursin DB, Brull SJ, Barker SJ, Rice MJ, Vender JS, Cohen NH: In Response. Anesth Analg 2015; 121:1680-2

O’Neal JB, Shaw AD: Predicting, preventing, and identifying delirium after cardiac surgery.

Perioper Med (Lond) 2016; 5:7

Qiao S, Olson JM, Paterson M, Yan Y, Zaja I, Liu Y, Riess ML, Kersten JR, Liang M, Warltier DC, Bosnjak ZJ, Ge ZD: MicroRNA-21 Mediates Isoflurane-induced Cardioprotection against Ischemia-Reperfusion Injury via Akt/Nitric Oxide Synthase/Mitochondrial Permeability Transition Pore Pathway. Anesthesiology 2015; 123:786-98

Rothman BS, Shotwell MS, Beebe R, Wanderer JP, Ehrenfeld JM, Patel N, Sandberg WS: Electronically Mediated Time-out Initiative to Reduce the Incidence of Wrong Surgery: An Interventional Observational Study. Anesthesiology 2016 Jun [Epub]

Orena EF, King AB, Hughes CG: The role of anesthesia in the prevention of postoperative delirium: a systematic review. Minerva Anestesiol 2016; 82:669-83 Oto J, Su Z, Duggan M, Wang J, King DR, Kacmarek RM, Jiang Y: Efficacy of coaxial ventilation with a novel endotracheal catheter equipped with a functional cuff: A swine model study. Eur J Anaesthesiol 2016; 33:250-6 Pallmann P, Pretorius M, Ritz C: Simultaneous comparisons of treatments at multiple time points: Combined marginal models versus joint modeling. Stat Methods Med Res 2015 Sep [Epub] Parker R, Rice MJ: Benefits of antioxidant supplementation in multi-trauma patients.

Romanian Journal of Anesthesia and Intensive Care 2015; 22:77-8 Patel MB, Jackson JC, Morandi A, Girard TD, Hughes CG, Thompson JL, Kiehl AL, Elstad MR, Wasserstein ML, Goodman RB, Beckham JC, Chandrasekhar R, Dittus RS, Ely EW, Pandharipande PP: Incidence and Risk Factors for Intensive Care Unit-related Post-traumatic Stress Disorder in Veterans and Civilians. Am J Respir Crit Care Med 2016; 193:1373-81 Patil NK, Luan L, Bohannon JK, Guo Y, Hernandez A, Fensterheim B, Sherwood ER: IL-15 Superagonist Expands mCD8+ T, NK and NKT Cells after Burn Injury but Fails to Improve Outcome during Burn Wound Infection.

PLoS One 2016; 11:e0148452 Phillips ML, Willis BC, Broman AJ, Lam HV, Nguyen TT, Austin TM: Bimodal analgesia vs fentanyl in pediatric patients undergoing bilateral myringotomy and tympanostomy tube placement: a propensity matched cohort study. J Clin Anesth 2016; 32:162-8 Price CC, Levy SA, Tanner J, Garvan C, Ward J, Akbar F, Bowers D, Rice M, Okun M: Orthopedic Surgery and Post-Operative Cognitive Decline in Idiopathic Parkinson’s Disease:

Raghunathan K, Bonavia A, Nathanson BH, Beadles CA, Shaw AD, Brookhart MA, Miller TE, Lindenauer PK: Association between Initial Fluid Choice and Subsequent In-hospital Mortality during the Resuscitation of Adults with Septic Shock. Anesthesiology 2015; 123:1385-93 Rathmell JP, Strichartz G, Wanderer J: Neosaxitoxin versus Traditional Local Anesthetics: Mechanism of Action and Sites of Notable Effect. Anesthesiology 2015; 123(4):A23 Rathmell JP, Wanderer JP: Unraveling the Neurobiology of Consciousness: Anesthesia, Loss of Behavioral Response to Stimuli, and Functional Connectivity in the Brain. Anesthesiology 2016; 124(4):A21 Reynolds WS, Dmochowski R, Wein A, Bruehl S: Does central sensitization help explain idiopathic overactive bladder? Nat Rev Urol 2016 Rice MJ, Coursin DB: Glucose Meters: Here Today, Gone Tomorrow? Crit Care Med 2016; 44:e97-100 Rice MJ, Morey TE, Sappenfield JW, Gravenstein N: In Response. Anesth Analg 2016; 122:581 Rice SD, Rice MJ, Wedig G: Is Our US Health Care System Actually a Market-Based Economy? Anesth Analg 2015; 121:1114-5 Richardson MG, Domaradzki KA, McWeeney DT: Implementing an Obstetric Emergency Team Response System: Overcoming Barriers and Sustaining Response Dose. Jt Comm J Qual Patient Saf 2015; 41:514-21 Rooks HJ, Anthony JR, Sexton KW, Marshall AP, Guillamondegui OD, Ehrenfeld JM, Shack RB, Thayer WP: Transfers for Hand Surgery

Saddawi-Konefka D, Hung SL, Kacmarek RM, Jiang Y: Optimizing Mask Ventilation: Literature Review and Development of a Conceptual Framework. Respir Care 2015; 60:1834-40 Sappenfield JW, Rice MJ, Gravenstein N, Morey TE: Still Waiting for Evidence That Current Noninvasive Hemoglobinometry Adds Value.

Anesth Analg 2016 Jun [Epub] Sathiyakumar V, Shi H, Thakore RV, Lee YM, Joyce D, Ehrenfeld J, Obremskey WT, Sethi MK: Isolated sacral injuries: Postoperative length of stay, complications, and readmission. World J Orthop 2015; 6:629-35 Semler MW, Rice TW, Ehrenfeld JM: Leveraging Clinical Informatics in the Conduct of Clinical Trials. J Med Syst 2015; 39:112 Semler MW, Rice TW, Shaw AD, Siew ED, Self WH, Kumar AB, Byrne DW, Ehrenfeld JM, Wanderer JP: Identification of Major Adverse Kidney Events Within the Electronic Health Record. J Med Syst 2016; 40:167 Shaw AD, Schermer CR, Lobo DN, Munson SH, Khangulov V, Hayashida DK, Kellum JA: Impact of intravenous fluid composition on outcomes in patients with systemic inflammatory response syndrome. Crit Care 2015; 19:334 Siew ED, Basu RK, Wunsch H, Shaw AD, Goldstein SL, Ronco C, Kellum JA, Bagshaw SM, 15th ADQI Consensus Group: Optimizing administrative datasets to examine acute kidney injury in the era of big data: workgroup statement from the 15(th) ADQI Consensus Conference. Can J Kidney Health Dis 2016; 3:12 Sileshi B, O’Hara BK, Davis ME, Haglund NA, Meng X, Deegan R, Stulak JM, Kushwaha SS, Shaw A, Maltais S: Outcomes of Patients Implanted Using a Left Thoracotomy Technique for A Miniaturized Centrifugal Continuous-Flow Pump. ASAIO J 2016 Jun [Epub] Simmons SF, Schnelle JF, Sathe NA, Slagle

JM, Stevenson DG, Carlo ME, McPheeters ML: Defining Safety in the Nursing Home Setting: Implications for Future Research. J Am Med Dir Assoc 2016; 17:473-81 Slagle JM, Anders S, Porterfield E, Arnold A, Calderwood C, Weinger MB: Significant Physiological Disturbances Associated With Non-Routine Event Containing and Routine Anesthesia Cases. J Patient Saf 2015; 11:198203 Smith HA, Gangopadhyay M, Goben CM, Jacobowski NL, Chestnut MH, Savage S, Rutherford MT, Denton D, Thompson JL, Chandrasekhar R, Acton M, Newman J, Noori HP, Terrell MK, Williams SR, Griffith K, Cooper TJ, Ely EW, Fuchs DC, Pandharipande PP: The Preschool Confusion Assessment Method for the ICU: Valid and Reliable Delirium Monitoring for Critically Ill Infants and Children. Crit Care Med 2016; 44:592-600 Smith JL, Rice MJ: Why Have So Many Intravascular Glucose Monitoring Devices Failed? J Diabetes Sci Technol 2015; 9:782-91 Stark RJ, Choi H, Koch SR, Fensterheim BA, Lamb FS, Sherwood ER: Endothelial cell tolerance to lipopolysaccharide challenge is induced by monophosphoryl lipid A. Clin Sci (Lond) 2016; 130:451-61 Starnes JR, McEvoy MD, Ehrenfeld JM, Sandberg WS, Wanderer JP: Automated Case Cancellation Review System Improves Systems-Based Practice. J Med Syst 2015; 39:134 Stewart MK, Romain CV, Banerjee A, Li W, Murphy AJ, Sexton KW, Webb LE, Terhune KP: Peer resident assessment in surgical education: is it equivalent to expert attending assessment? Journal of the American College of Surgeons 2015; 221:e74-e75 Sun LS, Li G, Miller TL, Salorio C, Byrne MW, Bellinger DC, Ing C, Park R, Radcliffe J, Hays SR, DiMaggio CJ, Cooper TJ, Rauh V, Maxwell LG, Youn A, McGowan FX: Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood. JAMA 2016; 315:2312-20 Swale DR, Kurata H, Kharade SV, Sheehan J, Raphemot R, Voigtritter KR, Figueroa EE, Meiler J, Blobaum AL, Lindsley CW, Hopkins CR, Denton JS: ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels. ACS Chem Neurosci 2016; 7:1013-23 37

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Tabing AK, Ehrenfeld JM, Wanderer JP: Limiting the accessibility of cost-prohibitive drugs reduces overall anesthetic drug costs: a retrospective before and after analysis. Can J Anaesth 2015; 62:1045-54 Taibo CL, Moon TD, Joaquim OA, Machado CR, Merchant A, McQueen K, Sidat M, Folgosa E: Analysis of trauma admission data at an urban hospital in Maputo, Mozambique. Int J Emerg Med 2016; 9:6 Talbot TR, Carr D, Parmley CL, Martin BJ, Gray B, Ambrose A, Starmer J: Sustained Reduction of Ventilator-Associated Pneumonia Rates Using Real-Time Course Correction With a Ventilator Bundle Compliance Dashboard.

Infect Control Hosp Epidemiol 2015; 36:1261-7 Terekhov MA, Ehrenfeld JM, Wanderer JP: Preoperative Surgical Risk Predictions Are Not Meaningfully Improved by Including the Surgical Apgar Score: An Analysis of the Risk Quantification Index and Present-On-Admission Risk Models. Anesthesiology 2015; 123:1059-66 Thakore RV, Greenberg SE, Shi H, Foxx AM, Francois EL, Prablek MA, Nwosu SK, Archer KR, Ehrenfeld JM, Obremskey WT, Sethi MK: Surgical site infection in orthopedic trauma: A case-control study evaluating risk factors and cost. J Clin Orthop Trauma 2015; 6:220-6 Thomas S, Meadows J, McQueen KA: Access to Cesarean Section Will Reduce Maternal Mortality in Low-Income Countries: A Mathematical Model. World J Surg 2016; 40:1537-41 Uner A, Goncalves GH, Li W, Porceban M, Caron N, Schonke M, Delpire E, Sakimura K, Bjorbaek C: The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis. Mol Metab 2015; 4:678-91 Vasilevskis EE, Pandharipande PP, Graves AJ, Shintani A, Tsuruta R, Ely EW, Girard TD: Validity of a Modified Sequential Organ Failure Assessment Score Using the Richmond Agitation-Sedation Scale. Crit Care Med 2016; 44:138-46 Vasilopoulos T, Morey TE, Dhatariya K, Rice MJ: Limitations of Significance Testing in Clinical Research: A Review of Multiple Comparison Corrections and Effect Size Calculations with Correlated Measures. Anesth Analg 2016; 122:825-30

Vincent JL, Shehabi Y, Walsh TS, Pandharipande PP, Ball JA, Spronk P, Longrois D, Strom T, Conti G, Funk GC, Badenes R, Mantz J, Spies C, Takala J: Comfort and patient-centred care without excessive sedation: the eCASH concept. Intensive Care Med 2016; 42:962-71 Walters JL, Jackson T, Byrne D, McQueen K: Postsurgical pain in low- and middle-income countries. Br J Anaesth 2016; 116:153-5 Wanderer JP, Gruss CL, Ehrenfeld JM: Using Visual Analytics to Determine the Utilization of Preoperative Anesthesia Assessments. Appl Clin Inform 2015; 6:629-37 Wanderer JP, McQueen K, Rathmell JP: Anesthesiologists Without Borders: Working for Better Surgical Outcomes in Resource Limited Settings. Anesthesiology 2016; 124(3):A21 Wanderer JP, Nathan N: Pre- and Postoperative Troponin Elevation: Effects on Postoperative Mortality. Anesth Analg 2016; 123:1 Wanderer JP, Rathmell JP: A Brief History of the Perioperative Surgical Home. Anesthesiology 2015; 123(1):A23 Wanderer JP, Rathmell JP: A Changing Anesthesiology Workforce: East and West, Males and Females, Then and Now. Anesthesiology 2015; 123(5):A23 Wanderer JP, Rathmell JP: Accelerated Recovery: From a Fortnight to Four Nights.

Anesthesiology 2015; 123(6):A23 Wanderer JP, Rathmell JP: ADVERSE Drug Events: Incidence & risk reduction across the care continuum. Anesthesiology 2016; 124(1):A23 Wanderer JP, Rathmell JP: Anesthesiologists & Ultrasonography: A Historical Window.

Anesthesiology 2015; 123(3):A23 Wanderer JP, Rathmell JP: Assessing the Quality of Anesthesia Quality Metrics. Anesthesiology 2016; 124(6):A21

124(5):A21 Wanderer JP, Rathmell JP: Randomized Controlled Trials vs. Administrative Database Studies. Anesthesiology 2015; 123(2):A23 Whitney GM, Woods MC, France DJ, Austin TM, Deegan RJ, Paroskie A, Booth GS, Young PP, Dmochowski RR, Sandberg WS, Pilla MA: Reducing intraoperative red blood cell unit wastage in a large academic medical center.

Transfusion 2015; 55:2752-8 Wills TA, Baucum AJ, 2nd, Holleran KM, Chen Y, Pasek JG, Delpire E, Tabb DL, Colbran RJ, Winder DG: Chronic intermittent alcohol disrupts the GluN2B-associated proteome and specifically regulates group I mGlu receptor-dependent long-term depression. Addict Biol 2015 Nov [Epub] Wu A, Brovman EY, Whang EE, Ehrenfeld JM, Urman RD: The Impact of Overestimations of Surgical Control Times Across Multiple Specialties on Medical Systems. J Med Syst 2016; 40:95 Wynn JL, Wilson CS, Hawiger J, Scumpia PO, Marshall AF, Liu JH, Zharkikh I, Wong HR, Lahni P, Benjamin JT, Plosa EJ, Weitkamp JH, Sherwood ER, Moldawer LL, Ungaro R, Baker HV, Lopez MC, McElroy SJ, Colliou N, Mohamadzadeh M, Moore DJ: Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18. Proc Natl Acad Sci USA 2016; 113:E2627-35 Yeung CK, Billings FTt, Claessens AJ, Roshanravan B, Linke L, Sundell MB, Ahmad S, Shao B, Shen DD, Ikizler TA, Himmelfarb J: Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress. BMC Nephrol 2015; 16:183 Zhu L, McDavid S, Currie KP: “Slow�

Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA). PLoS One 2015; 10:e0134117 Book Chapters

Wanderer JP, Rathmell JP: Perioperative and Acute Care Transfusion Strategies: One size may not fit all. Anesthesiology 2016; 125(1):A21

Adams J, Wolfe JW, Ehrenfeld JM: Pharmacology of adjunct agents. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016

Wanderer JP, Rathmell JP: Postoperative Acute Kidney Injury: Risk Factors and Possible Interventions. Anesthesiology 2016;

Adams J, Wolfe JW, Ehrenfeld JM: Pharmacology of inhalational agents. In: Ehrenfeld JM,

Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Adams J, Wolfe JW, Ehrenfeld JM: Pharmacology of intravenous agents. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Adams J, Wolfe JW, Ehrenfeld JM: Pharmacology of local anesthetics. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Adams J, Wolfe JW, Ehrenfeld JM: Pharmacology principles. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition.

New York, New York: Springer; 2016 Atkins JH, Ehrenfeld JM: Ambulatory surgery and out of OR procedures. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Atkins JH, Ehrenfeld JM: Physiology and anesthesia for neurologic, ENT and ophthalmologic surgery. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition.

New York, New York: Springer; 2016 Badr R, Ehrenfeld JM: Physiology and anesthesia for general and bariatric. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Barnett S, Pratt S, Ehrenfeld JM: Professionalism, safety, and teamwork. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Baysinger CL, Staat B: Uteroplacental anatomy, blood flow, respiratory gas excahnge, drug transfer, and teratogenicity. In: Baysinger C, Bucklin B, Gambling D, eds. A Practical Approach to Obstetric Anesthesia, 2nd edition. Philadelphia, Pennsylvania: Wolters Kluwer; 2016, pp 19-33 Bose R, Ehrenfeld JM: Physiology and anesthesia for elderly patients. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd

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edition. New York, New York: Springer; 2016 Dittrich K: Headaches. In: Huntoon M, ed.

A Review of Pain Medicine for Board Exams.

New York, New York: Oxford University Press; 2016 Edwards DA, Boezaart AP: The applied anatomy of the abdominal and pelvic sympathetic ganglia. In: Boezaart AP, ed. The Anatomical Foundations of Regional Anesthesia and Acute Pain Medicine. Potomac, Maryland: Bentham Science Publishers; 2016 Edwards DA, Le-Wendling L, Kent M, Tighe P: The acute pain team. In: Stuart-Smith K, ed.

Perioperative Medicine - Current Controversies. New York, New York: Springer; 2016 Ehrenfeld JM: Ethical and legal issues in anesthesia. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Ehrenfeld JM: Physiology & anesthesia for urologic surgery. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition.

New York, New York: Springer; 2016 Hays SR, Deshpande JK: Neurotoxicity of anesthesia on developing brain. In: Baheti DK, Dhayagude SH, Deshpande JK, Menon R, eds. World Clinics Anesthesia, Critical Care, & Pain Pediatric Anesthesia-II. New Delhi, India: Jaypee; 2015, pp 117-42 Hernandez, A., Sherwood, ER: Anesthesiology principles, pain management, and conscious sedation. In: Townsend CM, Beauchamp RD, Evers MB, Mattox KL, eds. Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice, 20th edition. Philadelphia, Pennsylvania: Elsevier; 2016 Kingeter A, McEvoy MD: Electrolytes and acid-base analysis. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition.

New York, New York: Springer; 2016 Kingeter A, McEvoy MD: Fluids and transfusion therapy. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition.

New York, New York: Springer; 2016 Lai D, Ehrenfeld JM: History of anesthesia and introduction to the specialty. In: Ehrenfeld

JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 McLean BC, Plunkett A, Ehrenfeld JM: Anesthetic techniques: General, sedation, MAC. In: Ehrenfeld JM, Urman RD, Segal, S, eds.

Anesthesia Student Survival Guide: A CaseBased Approach, 2nd edition. New York, New York: Springer; 2016 McLean BC, Plunkett A, Ehrenfeld JM: Anesthetic techniques: Regional. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Nava RD, Bhalla T, Ehrenfeld JM: Postoperative care unit and common postoperative problems. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Newton, MW: Anaesthesia for emergency pediatric general surgery. In: Homer R, Walker I, Bell G, eds. Update in Anaesthesia: Paediatric Anaesthesia and Critical Care (Special Edition). United Kingdom: World Federation of Societies of Anaesthesiologists; 2015, Vol 30, No 1, pp 178-86. ISBN: 1353-4882 Newton, MW: Major elective surgery in children, and surgery in remote and rural locations. In: Homer R, Walker I, Bell G, eds.

Update in Anaesthesia: Paediatric Anaesthesia and Critical Care (Special Edition). United Kingdom: World Federation of Societies of Anaesthesiologists; 2015, Vol 30, No 1, pp 13340. ISBN: 1353-4882 Ori A, Ehrenfeld JM: Quality assurance, patient and provider safety. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Richardson MG, DiMiceli-Zsigmond M: Fetal assessment. In: Baysinger C, Bucklin B, Gambling D, eds. A Practical Approach to Obstetric Anesthesia, 2nd edition. Philadelphia, Pennsylvania: Wolters Kluwer; 2016 Romanelli T: Pediatric surgery. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016

Shah PR, Wagner C, Shaw A: Echocardiography and ultrasound in the intensive care unit. In: Evans AS, Kerr GE, Chung I, Varghese R, eds. Modern Concepts and Practices in Cardiothoracic Critical Care. Hershey, Pennsylvania: IGI Global; 2015, pp 890-907. ISBN: 9781466686038 Urman RD, Ehrenfeld JM: Malignant hyperthermia. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Walters JL, McEvoy MD: Peripheral, arterial, and central lines and gastric tube placement.

In: Ehrenfeld JM, Urman RD, Segal, S, eds.

Anesthesia Student Survival Guide: A CaseBased Approach, 2nd edition. New York, New York: Springer; 2016 Westman A, McEvoy MD: Intraoperative problems. In: Ehrenfeld JM, Urman RD, Segal, S, eds. Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016 Whitney,Gina, Suanne Daves, Brian Donahue: Multiorgan effects of congenital cardiac surgery. In: Andropoulos DB, Stayer SA, Mossad EB, Miller-Hance WC, eds. Anesthesia for Congenital Heart Disease, 3rd edition.

Hoboken, New Jersey: John Wiley & Sons, Inc.; 2015 Young JL, Lockhart EM, Baysinger CL: Management of the opioid dependent parturient.

In: Baysinger C, Bucklin B, Gambling D, eds.

A Practical Approach to Obstetric Anesthesia, 2nd edition. Philadelphia, Pennsylvania: Wolters Kluwer; 2016, pp 655-67 Books and Guides Baysinger C, Bucklin B, Gambling D, eds: A Practical Approach to Obstetric Anesthesia, 2nd edition. Philadelphia, Pennsylvania: Wolters Kluwer; 2016 Eckstrand KL, Ehrenfeld JM, eds: Lesbian, Gay, Bisexual, and Transgender Healthcare: A Clinical Guide to Preventive, Primary, and Specialist Care. New York, New York: Springer; 2016 Ehrenfeld JM, Urman RD, Segal S, eds: Anesthesia Student Survival Guide: A Case-Based Approach, 2nd edition. New York, New York: Springer; 2016

Frederickson TW, Gordon DB, De Pinto M, Kral LA, Furnish T, Gupta RK, Austin PN, eds: Reducing Adverse Drug Events Related to Opioids Implementation Guide. Philadelphia, Pennsylvania: Society of Hospital Medicine; 2015 Wiklund ME, Kendler J, Hochberg L, Weinger M B: Technical Basis for User Interface Design of Health IT (NIST GCR 15-996). Washington, DC: National Institute of Standards and Technology, US Department of Commerce; September, 2015 Case Reports Alvis BD, Sobey CM: Oral Baclofen Withdrawal Resulting in Progressive Weakness and Sedation Requiring Intensive Care Admission. The Neurohospitalist 2016; Mar:1941874416637404 Bennett JM, Deegan R, Maltais S, Pretorius M: Failed Percutaneous Transcatheter Tricuspid Valve-in-Valve Replacement Caused

by Retained Valve Holder. Anesth Analg 2016; 122:34-6 Bick JS, Kennedy J, Siegrist K, Mudrick J, Hernandez A, Bennett J, Wagner CE: Malignant Hyperthermia During Double-Lung Transplantation. J Cardiothorac Vasc Anesth 2016; 30:443-5 Cropsey CL, McEvoy MD: Local Anesthetic Systemic Toxicity in a Nonoperative Location.

Simul Healthc 2015; 10:326-8 Epstein RH, St Jacques PJ, Wanderer JP, Bombulie MR, Agarwalla N: Prophylactic Antibiotic Management of Surgical Patients Noted as “Allergic” to Penicillin at Two Academic Hospitals. A A Case Rep 2016; 6:263-7 Franklin AD, Menser CC, Naftel RP: Fluoroscopically Guided Epidural Blood Patch Effective for Treatment of a Postsurgical Pseudomeningocele in a Pediatric Patient.

Reg Anesth Pain Med 2016; 41:542-3 Jelly CA, Jiang Y, Hoeft M, Liang Y: Transesophageal Echocardiography Assisting in the Diagnosis of Intraabdominal Hemorrhage During Cardiac Arrest. A A Case Rep 2016; 6:201-3 Lorinc A: Case 2015-1: ‘My Aircraft’ – ‘Your Aircraft’ – A Look at a Standardized Communication Case: A Case Report from the Anesthesia Incident Reporting System. ASA Newsletter 39

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2016; Jan Mahanna E, Edwards DA, Tarante N, Rahman M, Petersen JW, Bihorac A: Variant Neurogenic Stunned Myocardium in a Young Female After Subarachnoid Hemorrhage. A A Case Rep 2016; 6:10-13 Mehr SR, Neeley RC, Wiley M, Kumar AB: Profound Autonomic Instability Complicated

by Multiple Episodes of Cardiac Asystole and Refractory Bradycardia in a Patient with Anti-NMDA Encephalitis. Case Rep Neurol Med 2016; 2016:7967526 Sobey JH, Franklin A: Ultrasound-Guided Tibial Nerve Block for Definitive Treatment of Tarsal Tunnel Syndrome in a Pediatric Patient.

Reg Anesth Pain Med 2016; 41:415-6 Townley KR, Lane J, Packer R, Gupta RK: Unintentional Infusion of Phenylephrine into the Epidural Space. A A Case Rep 2016; 6:124-6 Editorials/Commentaries/Book Reviews Bansal V, Shastri U, Gupta R, Canlas C: Continuous Perineural Catheters for Postoperative Pain From an Ambulatory Surgery Center. Reg Anesth Pain Med 2016; 41:543 Baysinger CL: Editorial comment on Ranganathan et al. Chronic headache and backache are long-term sequelae of unintentional dural puncture in the obstetric population, J Clin Anesth 2015; 27:201-6. Obstetric Anesthesia Digest 2016; 36:4-5 Baysinger CL: Editorial comment on Reinikainen et al. Continuous wound infiltration with ropivacaine for analgesia after caesarean section: a randomized, placebo controlled trial, Acta Anaestheseiol Scand 2014; 58:973-79.

Obstetric Anesthesia Digest 2015; 35:167-8 Baysinger CL: Editorial comment on Weigand et al. Buprenorphine and naloxone compared with methadone treatment in pregnancy, Obstet Gynecol 2015; 125:363-8. Obstetric Anesthesia Digest 2015; 35:192-3 Benkwitz C, Watkins SC, Donahue BS: Assessing the Risks of Noncardiac Surgery for Children With Congenital Heart Disease. J Am Coll Cardiol 2016; 67:802-3 Chi MH, Rice MJ: Propofol: To shake or not to shake. Romanian Journal of Anesthesia and Intensive Care 2016; 1:5-6

Edwards DA: Fentanyl: widely used, deadly when abused. The Conversation, June 16, 2016 http://theconversation.com/fentanyl-widelyused-deadly-when-abused-60511 Accessed July 30, 2016

RC, Neder M, Plohal A, Sims NM, Sparnon E, Trbovich P, Weinger MB: A Roundtable Discussion: Working Toward Safer, Easier-to-Use Infusion Systems. Biomed Instrum Technol 2015; Suppl:6-12

Edwards DA: Opioid epidemic affects all Tennesseans. The Tennessean, April 24, 2016 http://www.tennessean.com/story/opinion/ contributors/2016/04/24/opioid-epidemic-affects-all-tennesseans/83197228/ Accessed July 30, 2016

McEvoy MD, Lien CA: Education in Anesthesiology: Is It Time to Expand the Focus? A A Case Rep 2016; 6:380-2

Ehrenfeld JM, Spickard WA, 3rd, Cutrer WB: Medical Student Contributions In The Workplace: Can We Put a Value on Priceless? J Med Syst 2016; 40:128

McQueen K: Oxygen: The Missing Element in Low-Income Countries. World J Surg 2016; 40:249-50

Ehrenfeld JM: The Storm Abroad: Anesthesiology During Wartime: Giving Blood on the Battlefield. Anesthesiology News 2015 Oct; 41(10) Ely EW, Pandharipande PP: The Evolving Approach to Brain Dysfunction in Critically Ill Patients. JAMA 2016; 315:1455-6 Harvey S: Dealing with Deception: A Perspective on Malingering. Anesthesiology News 2016; May Hester D: Master Techniques in Upper and Lower Airway Management. Anesth Analg 2016; 122:914 Isono S, Sandberg WS, Jiang Y: Do You Believe What You See or What You Hear? Ultrasound versus Stethoscope for Perioperative Clinicians. Anesthesiology 2016; 124:989-91 Jiang Y, Shaw AD: Albumin Supplementation as a Therapeutic Strategy in Cardiac Surgery: Useful Tool or Expensive Hobby? Anesthesiology 2016; 124:983-5 Kellum JA, Shaw AD: Assessing Toxicity of Intravenous Crystalloids in Critically Ill Patients.

JAMA 2015; 314:1695-7 Kilkelly SR, McEvoy MD: Review of Barash’s Clinical Anesthesia Fundamentals. Anesth Analg 2016; 122:1715-16 King AB, McEvoy MD, Fowler LC, Wanderer JP, Geiger TM, Furman WR, Sandberg WS: Disruptive Education: Training the Future Generation of Perioperative Physicians. Anesthesiology 2016; 125:266-8 Logan MK, Benjamin BE, Blake N, Chapman

McEvoy MD: The Add-on. Anesthesiology 2016; 125:412-3

McQueen K: Realities of Anesthesia Care in Resource-limited Settings. Anesthesiology 2016; 124:521-2 Nguyen TT, Donahue BS: Sex matching and red cell safety. J Thorac Cardiovasc Surg 2016; 152:233-4 Sandberg WS: Searching for Meaningful Topics of Improvement in Anesthesiology.

Anesthesiology 2016; 124:261-3 Sandberg WS, Talbot TR: Injection Rhymes with Infection? Anesthesiology 2016; 124:7524 Schetz M, Shaw AD, Vincent JL: Is the literature inconclusive about the harm of HES? We are not sure. Intensive Care Med 2016 Mar [Epub] Schlesinger J: Pulse Oximetry: Perception, Pitch, Psychoacoustics, and Pedagogy. Anesth Analg 2016; 122:1253-5 Schlesinger JJ: Making Opioids Safer at the End-of-Life. The Doctor Weighs In, July 30, 2015 http://thedoctorweighsin.com/makingopioids-safer-at-the-end-of-life/ Accessed July 30, 2016 Sherwood ER: What’s New in Shock? October 2015. Shock 2015; 44:291-3 Sobey CM, King AB, McEvoy MD: Postoperative Ketamine: Time for a Paradigm Shift. Reg Anesth Pain Med 2016; 41:424-6 Wanderer JP, Poler SM, Rothman BS: Show Me the Data! A Perioperative Data Warehouse of Epic Proportions. Anesth Analg 2016; 122:1742-3

Letters Camann WR, Baysinger CL, Collins MR, Vallejo MC, Anderson J, Wood CL, Hawkins JL, Carvalho B, Rollins MD, Bishop J, Brumley J: How to say “Yes” to nitrous oxide for Labor. Society for Obstetric Anesthesia and Perinatology Summer Newsletter 2015; 45:22-24 Davis RE, Hansen EN, Newton MW: FaithBased Organizations and Academic Global Surgery’s Moral Imperative. JAMA Surg 2016; 151:296 Kappen TH, Wanderer JP, Ehrenfeld JM, Weinger MB: Is Intraoperative Hypotension Truly a Too Simple Problem for Useful Decision Support? Anesth Analg 2016 Jun [Epub] Kla KM, Coursin DB, Rice MJ: Limitations of the Pupillary Reflex: Do the Eyes Have It? Anesthesiology 2015; 123:1480-1 Kynes JM, Watkins SC: A ‘Wake up’ call for our specialty-time to examine the impact of production pressure on patient safety. Paediatr Anaesth 2016; 26:667-8 Lam H, Nguyen TT, Austin TM: Routine epidurography for epidural placement in anesthetized pediatric patients. Paediatr Anaesth 2016; 26:326-7 Lubrano M, Wanderer JP, Ehrenfeld JM: Long-Term Opioid Therapy for Chronic Pain.

Ann Intern Med 2015; 163:147 McQueen KA: The Case for Oxygen in Global Surgical Care. World J Surg 2016; 40:1786 Riess ML, Aufderheide TP, Yannopoulos D: Therapeutic Hypothermia in Children. N Engl J Med 2015; 373:979-80 Saied N, Helwani MA, Pandharipande PP: Intraoperative protective ventilation: too early to redefine management parameters? BMJ 2015; 351:h5126 Schlesinger JJ: In Response. Anesth Analg 2015; 121:836 Tabing AK, Ehrenfeld JM, Wanderer JP: In reply: Observational study of prolonged times to tracheal extubation. Can J Anaesth 2016; 63:117-8 Tabing AK, Ehrenfeld JM, Wanderer JP: In reply: Sevoflurane or desflurane: Which one is more expensive? Limiting the accessibility of

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cost-prohibitive drugs: The story is incomplete. Can J Anaesth 2016; 63:361 Terekhov MA, Ehrenfeld JM, Wanderer JP: In Reply. Anesthesiology 2016; 124:1196-7 Newsletter Articles Brock JE: How SCOR Data Helps Tennessee Ambulatory Surgery Center Prove It’s Worth.

SAMBA Link 2016; Apr:12-12 McQueen K, Stabile M: Global Patient Safety.

ASA Monitor 2016; May Rice, MJ, Coursin DB: Measuring Glucose with Point-of-Care Meters: Be Careful! APSF Newsletter 2015; Oct Shah PR, Hernandez, A: Critical Care Ultrasound: Lessons Learned in Implementation.

Anesthesiology Newsletter 2015; 79:16-18 Sobey JH, Newton M, Romanelli T, Hummel, J: Worlds Apart: How Vanderbilt Children’s Hospital Pediatric Anesthesia Fellowship Fosters Leadership Skills in Global Health.

Society for Pediatric Anesthesia Newsletter, SPACIES, 2016; Summer (Volume 29, Number 2) http://www2.pedsanesthesia.org/newsletters/2016summer/spacies.html Accessed July 30, 2016 Poems Harvey ST: Alms. Ann Intern Med 2016; 164:341 Harvey ST: Reconnecting. JAMA 2016; 315:1171 Hester D: Roentgen’s Garden. JAMA 2015; 314:87 Hester D: Two Requests on Good Friday in the Preoperative Assessment Clinic. Journal of Medical Humanities 2016; 37:115

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Recognizing our faculty and staff New Clinical/Leadership Roles Brian Allen, MD, named the Director of the Regional Anesthesia and Acute Pain Medicine Fellowship Dr. Rob Deegan named Professor of Clinical Anesthesiology David Edwards, MD, PhD, named Clinical Service Chief of Inpatient Chronic Pain Service.

Raj Gupta, MD named Associate Professor of Anesthesiology Travis Hamilton, DO, appointed as Section Head of Regional Anesthesiology Services and Acute Pain Services Jenna Helmer-Sobey, MD, named Associate Fellowship Program Director

Achievements Carrie Menser, MD, named medical director for the Monroe Carell Jr Children’s Hospital at Vanderbilt (MCJCH) Post-Anesthesia Care Unit (PACU) Mark Newton, MD, named Professor of Anesthesiology Mias Pretorius, MBChB, MSCI, Associate Professor of Anesthesiology and Medicine, named Division Chief of Cardiothoracic Anesthesiology Mark Rice, MD named Associate Vice Chair for Clinical Affairs Paul St. Jacques, MD named Professor of Anesthesiology and Biomedical Informatics

Matthew McEvoy, MD, is now a member of the Vanderbilt Academy for Excellence in Teaching and joins members Warren Sandberg, MD, PhD, Scott Watkins, MD, Amy Robertson, MD, Jesse Ehrenfeld, MD, MPH, Michael Richardson, MD, Jane Easdown, MD, and Michael Pilla, MD. Also: Vanderbilt Academy for Excellence in Teaching members: Matthew • Selected as a member of McEvoy, MD, Jane Easdown, MD, Jesse Ehrenfeld, MD, MPH, Scott the FAER (Foundation for Anesthesia Education and Re- Watkins, MD, Amy Robertson, MD, Michael Richardson, MD, Warren search) Academy of Education S. Sandberg, MD, PhD Not pictured: Michael Pilla, MD Mentors in Anesthesiology.

Matthew McEvoy, MD, is one ley’s Cardiac Anesthesia textbook, along with of only 15 academy members and the first Dr. Glenn Gravlee and Dr. Karsten Bartels from the department. from UC Denver. Also:

Andrew Shaw, MB, FRCA, FFICM, FCCM named Executive Vice Chair.

Mark Rice, MD, named to the ABA MOCA Minute Committee as editor.

Doug Hester, MD named Associate Professor of Anesthesiology

Ban Sileshi, MD, named Associate Fellowship Director for the Cardiothoracic Anesthesia fellowship

Jill Kilkelly, MD named Associate Professor of Clinical Anesthesiology

Jason Slagle, PhD named Research Associate Professor of Anesthesiology

Adam King, MD, will begin a newly-created role as Clinical Chief of the Anesthesia Perioperative Consult Service

Chris Sobey, MD, named the Director of the Pain Fellowship program

Warren Sandberg, MD, PhD, served as a member of the Scientific Affairs Reference Committee at the 2015 ASA House of Delegates meeting which took place during the 2015 Annual ASA Meeting in San Diego, California. Also: • Named President-Elect of Tennessee Society of Anesthesiologists for 2016.

•Textbook Editorship Warren Sandberg, MD, PhD Anesthesiology, 3/e, 2016 Written and edited by an internationally renowned author team Defines today’s anesthesia practice for residents and practitioners alike Focuses on the most relevant topics in anesthesiology, perioperative medicine, critical care medicine, and pain medicine.

Antonio Hernandez, MD, named CVICU Medical Director

Buffy Lupear, CRNA, named Senior Quality and Patient Advisor within the Department

Liza Weavind, MD, MBBCh, FCCM, named Associate Division Chief of Anesthesiology Critical Care Medicine

Stuart McGrane, MB, ChB, named Associate Fellowship Program Director

Jonathan Wanderer, MD, MPhil, named Medical Director of the VAPIR Division

Kelly McQueen, MD, MPH, named Professor of Anesthesiology and Surgery

Liza Weavind, MD, MBBCh, FCCM named Professor of Anesthesiology and Surgery

Andrew Shaw, MB, FRCA, FFICM, FCCM has been invited to edit the 6th edition of Hens-

• Elected for membership into the FAER (Foundation for Anesthesia Education and Research) Academy of Research Mentors in Anesthesiology.

• Named as recipient of the 2015 Vicenza Award for his contributions to the field of international critical care nephrology.

• Scientific Program Committee Chair for the Society of Cardiovascular Anesthesiologists’ 2016 annual meeting.

Edward Sherwood, MD, PhD, has been selected to join the AUA Scientific Advisory Board for 2016 . The SAB is responsible for planning the scientific program of the AUA Annual Meeting. Also; •Invited to serve on the Promotions & Tenure Committee.

Clinical Arna Banerjee, MBBS, received the R. Michael Rodriguez Award for Excellence in Teaching at this year’s Faculty Award Ceremony.Also:

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• Named to the ASA’s Ad-Hoc Screen-Based Simulation Committee.

Curtis Baysinger, MD, is co-editor of the second edition of A Practical Approach to Obstetric Anesthesia, which will be published in the summer of 2016. Also: • TSA District 2 Director James Berry, MD, & Douglas Hester were recently appointed to the editorial board of “Mind-to-Mind” – the poetry section of the journal Anesthesiology.

Josh Billings, MD, MSCI, has been appointed to the scientific program committee for the Society of Cardiovascular Anesthesiology’s annual meeting.

David Chestnut, MD, is the 2016 ASA Rovenstine Lecturer. Also: • Textbook Editorship David H. Chestnut, MD Chestnut’s Obstetric Anesthesia: Principles and Practice, 5/e Published April 2014 “A comprehensive reference with updated evidence-based information, thoroughly referenced and cited, written by the leaders in the field of obstetric anesthesia” Jennifer E. Hofer, MD Univ. of Chicago Pritzker Sch. of Medicine

Christopher Cropsey, MD’s application titled, “Effects of an Electronic Decision Support Tool on Team Performance During In-situ Simulation of Perioperative Cardiac Arrest” has been approved for funding by FAER. Susan Eagle, MD, received a $270,000 grant from Baxter Medical for an investigator initiated trial “Peripheral intravenous device for detecting intravascular volume overload in dialysis patients.” Dr. Eagle is co-inventor of the IV device and is principal investigator of the trial. Also: • Co-founded startup company, Volumetrix, which has been recommended for Phase I STTR funding by the National Science Foundation for project: “Wireless point-of-care sensor for continuous fluid status monitoring of patients with congestive heart failure.” Volumetrix seeks to fulfill critical unmet needs in medicine by developing novel non-invasive devices and algorithms for intravascular volume status determination.

•Startup company, InvisionHeart LLC, received FDA clearance for their mobile wireless 12-lead ECG system. InvisionHeart has received awards from Google Entrepreneurs, NEXT award for best healthcare startup in Nashville, and the 2015 Southeastern Medical Device Association(SEMDA) for best emerging company. InvisionHeart was also one of 10 startups nationwide chosen to participate in the inaugural event that provides the opportunity to learn from experts and gain exposure to Silicon Valley investors.

Jesse Ehrenfeld, MD, MPH, has been named to the advisory committee of the Substitutable Medical Applications & Reusable Technology (SMART) Platforms project, AMA announced. The SMART project, created at Boston Children’s Hospital and Harvard Medical School, aims to provide doctors better EHR systems by developing “a flexible information infrastructure that allows for free, open development of plug and play applications (apps) to increase interoperability among health care technologies,” according to a news release. Also: • Editor-in-Chief, Journal of Medical Systems •Invited to serve as chair of the Administra-

tive Affairs Reference Committee at the 2015 House of Delegates meeting during the 2015 Annual ASA Meeting.

• Joined the Rewards, Recognition, and Retention Committee as a physician representative. This committee is being formed to reconfigure/replace the Elevate Steering Committee, which mainly met to adjudicate the Credo and Five Pillar Leader awards that were given out quarterly.

•Invited to serve on the ASA Committee on Anesthesia Care Team for the 2016 Governance year (October 2015-October 2016).

•Joined the OHSE as Director of Education Research, the National Health IT Safety Collaborative, and our hospital’s Hover Board Committee.

•Serving on this year’s VUSM Faculty Teaching and Clinical Service Awards Selection Committee.

•Co-chaired a panel on medical-school education reform at the Association of Health Care Journalists’ national conference in Cleveland, Ohio on April 9, 2016. He also addressed the conference of health journalists as a member of the American Medical Association’s Board of Trustees.

• Named director of education research for the Office of Health Sciences Education.

tions for interventional pain procedures (as opposed to the acute pain regional anesthesia blocks the previous app was directed towards). iOS - https://itunes.apple.com/us/ app/asra-coags-pain/id1033651708?mt=8 Android - https://play.google.com/store/apps/ details?id=com.asra.asracoagspain&hl=en

Rajnish Gupta, MD, has been offered to be part of the conference leadership for ASRA (American Society of Regional Anesthesia and Pain Medicine).

Duties will include: 2016 - Co-Workshop Chair for the 2016 ASRA Spring Meeting 2017 - Refresher Course Chair for the 2017 ASRA Spring Meeting 2018 - Workshop Chair for the 2018 ASRA World Congress on Regional Anesthesia and Pain Medicine 2019 - Chair of 2019 ASRA Spring Meeting

Jason Lane, MD, was elected to the board of directors at the Association of Anesthesia Clinical Directors’ annual meeting. Also, • Appointed chair of the Society of Non-Operating Room Interventionalists and Anesthesiologists (SONORIA) Collaboration committee. This committee is charged with the task of acting as a liaison to other societies and specialties (Radiology, Cardiology, Gastroen-

Doug Hester, MD was one of four “poets who heal” who read from their works April 19 at the Williamson County Public Library.

“Alternative Medicine: Poets Who Heal” was presented as part of the Vanderbilt University Lectures in the Library series.

Tracy Jackson, MD, presented “The Hardest Pill to Swallow” on chronic pain and opioid addiction at TEDx Nashville.

Shannon Kilkelly, DO, has been appointed to the Tennessee Board of Osteopathic Medical Examiners.

Avinash Kumar, MD, has been elected to the Neurosciences Section Council. Also: • Was confirmed on the PACT committee (Program Accreditation, Physician Certification & Fellowship Training (PACT) Committee for a four year term.

Rajnish Gupta, MD & Matthew McEvoy, MD published the iOS and Android versions of a new app developed in collaboration with ASRA, called ASRA Coags Pain. This app is based on the 2015 Guidelines published by ASRA on the use of Anticoagulant medica43

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terology).

Kelly McQueen, MD, MPH, was the recipient of and alumni award from The University of Vermont College of Medicine - the 2016 Service to Medicine & Community Award. Also, • ASA Alternate Delegate for TSA. Jason O’Neal, MD’s project titled “Neuroinflammation and postoperative delirium in cardiac surgery” approved for funding by VICTR, pending IRB approval. The project was was also approved for an Innovation Grant through the department.

Pratik Pandharipande, MD, MSCI, has been selected as a member of the FAER (Foundation for Anesthesia Education and Research) Academy of Research Mentors in Anesthesiology and joins academy members Warren Sandberg, MD, PhD, and Edward Sherwood, MD, PhD, within our department. Also, • Received a 2016 Presidential Citation from the Society of Critical Care Medicine.

• Received an invitation from Dr. Balser to participate in the School of Medicine Academic Leadership Program, which is produced by the Office of Faculty Affairs.

Brian Rothman, MD, selected to serve as Chair of ASA’s Committee on Electronic Media and Information Technology (October 2015) and President-Elect for the Society for Technology in Anesthesia.Also, • Invited to serve on the American Society of Anesthesiologists 2016 Ad Hoc Committee on Data Governance.

• Invited to participate in an ASA workgroup that will formulate a plan to help prepare members for the implementation of MACRA (the “Medicare Access and CHIP Reauthorization Act”), including the Merit-based Incentive Payment System (MIPS). This workgroup is tasked with determining appropriate criteria for EHR meaningful use for anesthesia care to propose them to the Centers for Medicare & Medicaid Services (CMS) for inclusion in the MIPS. • Chair of (HIMSS) Healthcare Information and Management Systems Society’s Connect-

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ed Health Committee.

• Serving on the ad hoc committee on Payment Reform. The Steering Committee will collect and assemble information from ASA members and task oriented workgroups to develop and answer specific questions about anesthesiology’s current state and necessary future direction relevant to the four components of MIPS and the development of APMs (Alternative payment models).

Jonathan Wanderer, MD, MPhil, has been selected to serve as an examiner for the American Board of Anesthesiology’s (ABA) Part 2 Examination. Also, • Invited to serve on the Anesthesia Quality Institute Data Use Committee. Committee and responsible for: Advising on the appropriate handling of research data requests on an ongoing basis (i.e., making a recommendation to the AQI Board on how research requests should be handled) Participating with the DUC in review of incoming data use requests Mentoring investigators in using NACOR (National Anesthesia Clinical Outcomes Registry) data • Invited by the American Board of Anesthesiology, Inc. (ABA) and American Society of Anesthesiologists (ASA) to serve on the newly created ABA/ASA Perioperative GME Workgroup to examine and review potential changes to the anesthesiology residency continuum of education to meet the present and future needs of our patients and health care systems.

• Associate editor for the Cover Editor and Illustrations section of Anesthesia & Analgesia.

• Co-PI on a National Science Foundation grant recently awarded to Biomedical Informatics. The project is entitled “TWC: Small: Analysis and Tools for Auditing Insider Accesses.”

• Co-investigator on Dr. Thomas Lasko’s R01 grant that was recently approved; “Identification, Extraction and Display of Clinical Data Patterns with Application to Anesthesia Workflows.”

Lisa Weavind, MD, MBBCh, FCCM, has been

elected to VU School of Medicine Faculty Senate. Also, • Led two remote bedside monitoring programs - Integrated Presence and Bedside Monitoring. Both offer real-time clinical information, early recognition and preemptive intervention to mitigate complications and improve patient outcomes.

CRNAs Middle Tennessee School of Anesthesia (MTSA) awarded Brad Koss, MS, CRNA Ikey DeVasher Distinguished Alumni Service Award and John Shields, DNP, CRNA - Clinical Excellence Award.

Education Residency class of 2020 Match: -7 of the 18 have dual degrees -57 Peer-reviewed abstract presentations and 45 peer-reviewed manuscript publications Leslie Fowler, MEd named to the AAPAE Council (Association of Anesthesiology Program Administrators & Educators). Also, • Application selected for the VUSOM Faculty Fellowship to Advance Medical Education.

This fellowship will provide two selected faculty members (or teams) with $25,000 per year for two years to develop and implement new programs, take existing programs to the next level, or scale up programs that have already been piloted successfully.

• Invited to participate as an alternate portfolio coach in the academic year 2015-16

by Vanderbilt’s Office of Health Sciences Education.

Elisabeth Hughes, MD and Leslie Fowler, MEd, received the Stephen Abrahamson’s Outstanding Innovation Award for their abstract “A Novel Approach to Randomization of ACGME Milestones into Daily Anesthesia Resident Evaluations” at the Innovations in Medical 7Education Conference held in February.

Michael Pilla, MD, appointed Vice Chair for the Problem-Based Learning Discussions ASA Committee for the 2017 governance year.

Also, • Invited to join the SOM Clinical Practice Appointments and Promotions Committee.

Amy Robertson, MD, appointed as Chair Designee of the Medical Student Education Committee for the Society of Education in Anesthesia.Also, • Proposal “Using Interactive Video to Teach Clinical Procedures” will be funded by the Vanderbilt Institute of Digital Learning.

Loren Smith, MD, PhD, received AUA’s Margaret Wood Resident Research Award and SOCCA’s Young Investigator Award for her abstract “A Novel Association Between High Density Lipoprotein Levels and the Risk of Acute Kidney Injury After Cardiac Surgery.”

Pediatrics Stephen Hays, MD, appointed to the Part 2 Test Writing Committee of the American Board of Anesthesiologists.

Amanda Lorinc, MD, elected as a Young Turk in the Society for Pediatric Anesthesia (SPA).

Camilla Lyon, MD, spent the month of November in Kenya in both Kijabe (Central Kenya) and Kisumu (Western Kenya) under imPACT Africa with Mark Newton, MD, and Matthew McEvoy, MD. The program is expanding from Kijabe to Kisumu with a nurse anesthesia school and simulation lab. During the month, Dr. Lyon provided junior and senior Kenyan nurse anesthesia students clinical training and discusssed school logistics with local leaders.

Mark Newton, MD, appointed to World Federation of Societies of Anaesthesiolgists (WFSA) for a one-year term as a member of the ASA Committee on Representation. Also, • Selected to receive the Nicholas M. Greene, MD Award for Outstanding Humanitarian Contribution by the ASA’s Committee on Global Humanitarian Outreach

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Heidi Smith, MD, MSCI, was invited to serve in the role of co-chair of the new Early Career Physician Council. Also, • Elected to Associate Membership in the Association of University Anesthesiologists (AUA).

• A BH Robbins Scholar (2011-2016) and assistant professor of Anesthesiology, is the principal investigator of groundbreaking research on pediatric delirium. The initiative monitors children hospitalized in Pediatric Critical Care Units (PCCUs) for delirium. Dr. Smith is mentored by Pratik Pandharipande, MD, MSCI .

Scott Watkins, MD, was elected Vice Chair for the anesthesia section of the Society for Simulation in Health Care.

Research Shilo Anders, PhD’s grant, “Dissemination Activities for Patient-Centered Non-Routine Events,” will be funded by the Patient Centered Outcome Research Institute (PCORI).

Julia Bohannon, PhD, has been endorsed by the VUMC Faculty Research Scholars program and offered a place in the program.

Stephen Bruehl, PhD, served on a panel led

by Michael Anastasi, Executive Editor of the Tennessean, discussing “The Culture of Pain Treatment/Pain Medication” at the inaugural Tennessee Pain, Opioids, Problems and Solutions Forum.

Kevin Currie, PhD, is serving a 5-year term on the editorial board of the Journal of Biological Chemistry (JBC).

Eric Delpire, PhD, invited to serve as a member of the Kidney Molecular Biology and Genitourinary Organ Development Study Section, Center for Scientific Review, for the term beginning July 1, 2015 and ending June 30, 2019. Members are selected on the basis of their demonstrated competence and achievement in their scientific discipline.

Study sections review grant applications submitted to the NIH, make recommendations on these applications to the appropriate NIH national advisory council or board, and survey the status of research in their fields of science. Also, • Grant entitled “Molecular and Functional characterization of the first known human mutation of the SLC12A2 gene” will be funded by the NIH. Jerod Denton, PhD, invited to join the Editorial Advisory Board for the American Journal of Physiology – Cell Physiology. Also, • Awarded with a contract from a Japanese pharmaceutical company, Ono pharmaceuticals. Goal is to develop pretherapeutic (and potentially therapeutic) compounds for a family of potassium channels implicated in diabetes, pain, and other diseases.

Daniel France, PhD, MPH awarded the “The Impact of NonRoutine Events on Neonatal Safety in the Perioperative Environment”

grant (Dan France, Matt Weinger, Jason Slagle, and Amanda Lorinc) Carrie Grueter, PhD’s Pilot & Feasibility grant proposal entitled “DGAT1 as a central regulator of diet-induced obesity” awarded for one year by Vanderbilt Diabetes Center.

PRESS COVERAGE

Naeem Patil, MBBS, PhD, selected to the ASPET (American Society for Pharmacology and Experimental Therapeutics) 2015 Washington Fellows Program. Dr. Patil will participate in advocating for increased support of the National Institutes of Health and other science agencies.

Chestnut to deliver Rovenstine Lecture

Vikram Tiwari, PhD, elected as “President Elect” of the Health Applications Society (HAS) within the Institute for Operations Research and the Management Sciences (INFORMS) for 2016. The position will automatically move up to “President” for 2017. HAS has 900 members worldwide. INFORMS has over 8,000 members worldwide. Dr. Tiwari will be running the HAS cluster in the next annual INFORMS conference, which will be held in Nashville November 13-16, 2016. Also, • Program chair of the Institute for Operations Research and the Management Sciences (INFORMS) 2015 healthcare conference, collaborated with leadership within Vanderbilt University Medical Center and Vanderbilt Owen Graduate School of Management. The conference had participants from 16 countries and 450 abstracts/posters/panels.

Twinkling Artifact Associated with Guidewire Placement

New colorectal surgery protocol reduces length of hospital stay by 25 percent Grant helps expand training outreach program in Kenya Dunworth named associate director of Advanced Practice, Anesthesia Undone in the ICU Owen and School of Medicine leaders co-chair international conference on analytics in health care July 29-31 ERAS Pathways Ideal for Improving Outcomes After Colorectal Surgery ERAS Pathways Within PSH Framework Ideal For Improving Colorectal Surgery Patient Outcomes ASA¹s Global Humanitarian Outreach Puts Emphasis on Epidemic of Surgical Data Reporting Through AIMS Automated Reporting Systems Can Improve Care Dr. Jesse Ehrenfeld: Proud to Serve Staff Breaks Help Improve Outcomes

American Board of Anesthesiology Part II Examiners

Association of University Anesthesiologists Members

James Berry, MD David Chestnut, MD Stephen Hays, MD Antonio Hernandez, MD Shannon Kilkelly, DO Edward Sherwood, MD, PhD Jonathan Wanderer, MD Matthew Weinger, MD

Jeffrey Balser, MD, PhD Arna Banerjee, MBBS Curtis Baysinger, MD Frederic T. (Josh) Billings, MD Stephen Bruehl, PhD David Chestnut, MD Brian Donahue, MD, PhD John Downing, MB, ChB Susan Eagle, MD

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New apps increase efficiency and safety for anesthesiologists

Jesse Ehrenfeld, MD, MPH Michael Higgins, MD, MPH Christopher Hughes, MD Yandong Jiang, MD, PhD Avinash Kumar, MD Lorri Lee, MD Matthew McEvoy, MD Kelly McQueen, MD, MPH Pratik Pandharipande, MBBS, MSCI

cont’d.

Mark Rice, MD Matthias Riess, MD, PhD Warren Sandberg, MD, PhD Andrew Shaw, MB, FRCA, FFICM, FCCM Edward Sherwood, MD, PhD Heidi Smith, MD, MSCI, FAAP Paul St. Jacques, MD Liza Weavind, MB, BCh, FCCM Matthew Weinger, MD

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PRESS COVERAGE cont’d.

Anesthesiologist Improves African Health Care VU-invented wireless ECG system receives FDA approval Preoperative Surgical Risk Predictions Are Not Meaningfully Improved by Including the Surgical Apgar Score: An Analysis of the Risk Quantification Index and Present-On-Admission Risk Models Taking better care of transgender patients Assessing Toxicity of Intravenous Crystalloids in Critically Ill Patients A Multimodal Intervention Improves Postanesthesia Care Unit Handovers AMA presses CMS for meaningful use hardship exemption GE Foundation Commits $25 Million to Global Safe Surgery Initiative

research awards Academy for Excellence in Teaching Pretorius named to key Anesthesiology post Faculty awards honor clinical, teaching, research excellence Vanderbilt Anesthesia broadens global efforts VUMC speakers shine at TEDx Nashville symposium Report highlights global need for surgical services Improving Care With the ASRA Coags Regional App Parents urged to use drug lockboxes to keep teens away from narcotics Opioid epidemic affects all Tennesseans Vanderbilt Medical Center initiative saves lives in Kenya Malignant hyperthermia: rare but potentially serious problem for surgical patients

Disruptive Education: Training the Future Generation of Perioperative Physicians Vanderbilt Anesthesiology Promotes Leadership and Diversity to Residents Capital needs grow for TN startups ADVERSE Drug Events: Incidence & risk reduction across the care continuum Shaw lauded for research mentorship Vanderbilt, Ono Pharmaceutical sign drug discovery agreement The upside of EHRs: 3 physicians’ perspectives on what they get right

responders to learn tourniquet use Hasty selected to participate in academic medicine program for women

Worlds Apart: How Vanderbilt Children’s Hospital Pediatric Anesthesia Fellowship Fosters Leadership Skills in Global Health

Vanderbilt tries to ease transgender challenges in health system

MorningLine: Opioid Addiction

Disruptive Education: Training the Future Generation of Perioperative Physicians

VUMC researchers seek to crack the code of neonatal sepsis America’s Growing Opioid Epidemic and Alternative Treatments for Pain (Additional coverage on 96.3 Jack FM and 106.7 FM)

Commanders have a lot to learn fast on transgender issue Changes in care improve recovery for surgery patients

Pain doctor and patient say long-term opioids cause pain, urge alternatives

As Non-OR Procedures Soar, New Guidelines Are Needed

Fentanyl: Widely Used, Deadly When Misused

Advanced Airway Training Needed for Anesthesiologists

AMA calls for ban on powdered alcohol

Schools of Nursing, Medicine create new LGBT health course

AMA Urges Physician Education on Use of Once-A-Day HIV Prevention

Anesthesiology resident (Loren Smith, MD, PhD) lands

In wake of Orlando shooting, AMA encourages first

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Office of the Chair 1211 21st Avenue South, 722 MAB Nashville, TN 37212 615-936-1595 www.vandydreamteam.com

Department of Anesthesiology Compassionate | Creative | Committed | Collaborative ANES GUIDEBOOK 16 landscape.indd 48

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