School of Chemistry Annual Report 2013
Never Stand Still
Faculty of Science
School of Chemistry
contents
of 03 head school report
67 Students
67 School of Chemistry Undergraduate Student Prizes
05 Mission Statement:
70 Postgraduate Student Awards and Prizes
06 Organisational Chart
71 SOCS Presidents Report
07 School of Chemistry Committees
75 Staff
08 Academic Responsibilities
11
academic staff
75
School 78 Invited Lectures & Conference Presentations – Emeritus & Visiting Fellows 79 Publications & Patents
39
86 Grants and Research Fellowships
RESEARCH
90 Industry and Community Interaction
39 Overview
93 Undergraduate and Postgraduate Enrolments
40 Research Highlights 44 School Postgraduate Seminars
98 Conference Presentations – Students
47 School Seminars – Invited Speakers
51
TEACHING AND LEARNING
101 Conference Posters
105
School Visiting Committee
51 Overview 52 First Year Chemsitry 53 Honours Program 54 Postgraduate Programs and Courses 55 Postgraduate Research 56 Outreach Activities 57 Asia Pacific Institute of Nuclear Science (APINS) Short Courses 59 Degrees Awarded 60 UNSW open day – September 62 Postgraduate Research Completions 63 Summer Scholarships 64 Practicum Students 65 Programs and Activities
107 Obituaries 111
Retirements
head of schoolreport sectionone head of school report academic staff research teaching and learning students school school visiting committee retirements obituaries
head of school report sectionone
01 The year of 2013 has been one of significant change and growth in staff and capabilities in the School of Chemistry. We were very fortunate to recruit three new professors during 2013. Professors Scott Kable and Tim Schmidt from Sydney University bring valuable research strength to the School and will add significant strength to the areas of molecular spectroscopy, molecular photophysics and renewable energy, and also in the general area of physical chemistry. Professor Martina Stenzel’s outstanding research record and expertise in polymers for biomedical applications, mainly drug delivery, will strengthen the School in both research and teaching, bringing an area of chemistry that is important in so many applications of chemistry, and has long been missing in the School. We have also been very fortunate in 2013 to appoint Dr Jonathan Beves, from Nanjing University and Dr Willam Alexander Donald who came from the University of Melbourne. At the same time as welcoming new staff, we have said farewell to two longstanding members of staff, Professor Brynn Hibbert, Professor of Analytical Chemistry and Dr Nick Roberts, Director of First year studies. The School once again had a very successful year with academics and PhD students winning a number of awards, locally and internationally. Scientia Professor Justin Gooding was recognized for his outstanding research contributions yet again with the New South Wales Science and Engineering Award for Emerging Research, and by being a finalist in the Eureka prizes for Interdisciplinary Science. Justin was also listed in the “Analytical Scientist” magazine as being one of the top 100 most influential analytical scientists worldwide in 2013. Dr. Jason Harper was awarded the Arc Postgraduate Council award for Excellence in Postgraduate Supervision, a tremendous acknowledgement of his contributions. Dr. Neeraj Sharma was awarded the NSW Tall Poppy award and the RACI Nyholm Lectureship, which enabled him to tour Australia giving inspiring lectures to young potential scientists, and Dr. Alex Donald was a finalist in the NSW Fresh Science awards. The School was very successful with grant funding, of particular note was Scientia Professor Justin Gooding and Associate Professor Pall Thordarson’s success in the award of their part of a new Centre of Excellence. With 9 poster prizes at local and international conferences as far flung as Turkey and Scotland, the PhD students have also done really well. Of special note was the award of the RACI Cornforth medal to David Hvasanov for the best PhD thesis in Australia in 2012. With a record additional 30 new PhD students in 2013, the School was really struggling with space for our research programs, and the University is working on providing additional space, with extra labs for our new recruits planned for 2014. As well as increases in postgraduate student numbers, we had an unprecedented number of enrolments into first year Chemistry, with 1070 students enrolled in the Higher and Lower Chemistry courses combined. To compare with previous numbers, there were 537
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students in Higher Chem S1, and in 2006 there were 200. Enrolments in the higher year courses are also very strong. Stephen Yannoulatis has been appointed as the new Manager, Student Services, which will be a big boost to the school’s student support. A significant event in the school was the audit of the school by Workcover in June, with a successful outcome. This was a part of an overall audit of UNSW, where Facilities Management and Chemistry were selected as the two specific sites for audit. Associate Professor Pall Thordarson and Dr. Toby Jackson put in a very significant effort to ensure we were ready for the audit, and the School thanks them for this. In addition, Associate Professor Pall Thordarson and Dr. Toby Jackson have made a significant University wide contribution by leading the way on campus with the introduction of a new chemical inventory system, SciQuest that will be the new University system for management of Hazardous Materials and Dangerous goods. As part of continuing to build a better interface to the world, the School launched a new web site, with thanks to Dr. Jon Beves and Dr. Ron Haines amongst others. The School maintained it’s strong community engagement by continuing to build strong links with the Science Teachers’ Association of NSW (STANSW) and with PhD students continuing the successful “Chemistry in the Bush” program. The school hosted high school students from a number of schools across Sydney as part of its School Visit program, and also hosted Year 10 work experience students Marking a special anniversary, August 2nd, 2013 was the 100th Anniversary of the UNSW Chemical Society, which we celebrated with a special event in the Scientia building, with guest lectures by alumni and eminent visiting scientists. A number of members of Professor H.G. Smith’s family joined the celebrations, celebrating the continuing contributions of our long standing Society. We had another very exciting year in 2013, with many successes and enthusiastic commitment from all members of the School. I would like to thank all of the staff and students who have contributed to the continued success of the school in 2013. Professor Barbara Messerle
head of school report / 05
Mission Statement:
The School of Chemistry aspires to continue as a leading chemistry school in the region. We aim to develop cutting edge knowledge to solve key challenges in the world today. Our research is focused in three research clusters Nanoscience, Medicinal Chemistry, and Energy and Catalysis. These research areas provide a base from which we take our research from the fundamentals of chemistry through to practical applications. We aim to excel in the education of our future scientific leaders and community members. We will continue to expand our interactions with institutions across the world, and build strong ties with our community, in particular industry and schools.
Goals: In order to remain a leading School in the region in both research and teaching, the School aims to grow to a size of 30 academic staff over the next five years. The growth will be targeted to maintain a balance of the three research clusters To increase our research funding and broaden the funding base of the research groups we will target international funding schemes and industry support.
A key goal is to achieve high quality publications in leading international journals with continued growth in terms of volume of output in publications with of higher impact. Postgraduate research students form the core of our research strength and we need to continue to grow the quality and number of our higher degree students, with particular focus on attracting the best UNSW students and high quality international students into postgraduate studies. As a School we constantly seek to improve our already high quality of teaching. We will achieve this by ensuring that the latest research developments in chemistry are included in our curricula and that our teaching materials both challenge our undergraduate students and nurture their love of chemistry. By engaging the students we aim to promote their life long learning of chemistry. To lead debate, we plan to expand our influence in the broader community. Our community engagement program will continue to target high schools across NSW and we will develop a new approach to our marketing strategy for students. We will grow the level of interactions with our alumni and focus on the inclusion of our alumni in the life of the School today.
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Organisational Chart
Head of School Deputy Head of School
Director of Research
Post Graduate Coordinator
Director of Teaching
School Manager
Deputy Director of Teaching
Technical & Building Manager
Office Administrator
Academic Staff Honours Coordinator
Post Graduate Administrator
Technical Staff
Stores
Postdocs 1st Year Coordinator
Student Services Manager
Undergraduate Teaching Coordinators
Undergraduate Administrator
Post Graduate Coursework Coordinator
Outreach Coordinator
Marketing
head of school report / 07
School of Chemistry Committees – 2013
School Research Committee
School Executive Committee
Teaching Committee
Prof. Barbara Messerle (Chair)
Dr Gavin Edwards (Chair)
Scientia Professor Justin Gooding A/Prof. John Stride A/Prof. Pall Thordarson Dr Gavin Edwards School Advisory Committee
Postgraduate Committee A/Prof. Jonathan Morris (Chair) Outreach Committee Dr Luke Hunter (Chair)
Prof. Barbara Messerle (Chair)
Health & Safety Committee
Prof. Naresh Kumar
A/Prof. Pall Thordarson (Chair, Jan - Jun)
A/Prof. John Stride A/Prof. Jonathan Morris A/Prof. Shelli McAlpine
A/Prof. Marcus Cole (Chair, Jul – Dec)
A/Prof. Pall Thordarson
Search Committee
Dr Gavin Edwards
Prof. Barbara Messerle (Chair)
Dr Toby Jackson Mr Rick Chan Mr Sveto Videnovic Research Committee A/Prof. John Stride (Chair) Prof. Barbara Messerle Scientia Professor Justin Gooding Prof. Naresh Kumar A/Prof. Steve Colbran A/Prof. Jonathan Morris Dr Graham Ball
Building & Space A/Prof. John Stride (Chair)
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Academic Responsibilities
Responsibility
Staff Member
Head of School
Professor Barbara Messerle
Deputy Head of School
Scientia Professor Justin Gooding
Director of Research
A/Prof. John Stride
Director of Teaching
Dr Gavin Edwards
Deputy Director of Teaching & Talented Students Program
Dr Jason Harper
Postgraduate Coordinator
A/Prof. Jonathan Morris
Honors Coordinator
A/Prof. Marcus Cole (Jan – Jun) A/Prof Shelli McAlpine (Jul – Dec)
Higher Year Coordinator (2-3rd year)
A/Prof. Pall Thordarson
Higher Year Laboratory Coordinator
A/Prof. Steve Colbran
1st Year Coordinator
Dr Nick Roberts (Jan – Jul) Dr Luke Hunter (Aug – Dec)
1st Year Laboratory Coordinator
Dr Ron Haines
Postgraduate Coursework Coordinator
Dr Graham Ball
Degree Program Coordinators
A/Prof. Jonathan Morris – Medicinal Chemistry A/Prof. Marcus Cole- Nanotechnology
Seminar Coordinator
Dr Neeraj Sharma
Outreach
Dr Luke Hunter
OHS
A/Prof. Pall Thordarson
IT
Dr Ron Haines
Academic staff: Back row: Dr Luke Hunter Dr Jason Harper, A/Prof. John Stride, A/Prof. Pall Thordarson, Dr Gavin Edwards, Dr Jon Beves, Dr Chuan Zhao, Dr Leigh Aldous Front row: A/Prof. Jonathan Morris, Professor Barbara Messerle (Head of School), Professor Naresh Kumar, Dr Ron Haines, Emeritus Professor Brynn Hibbert A/Prof. Shelli McAlpine, Anna Choy
head of school report / 09
academic staff sectiontwo head of school report academic staff research teaching and learning students school school visiting committee retirements obituaries
academic staff sectiontwo
02 Dr Leigh Aldous B.Sc (Hon), Leeds, CAST Ph.D. Queen’s University Belfast
Born in 1982, Dr Aldous completed his undergraduate degree at Leeds (2004) and postgraduate work at Queen’s University, Belfast (2007). He became a Postdoctoral Fellow at Queen’s University, Belfast (2007-2009), and then at The University of Oxford (2009 - 2011). Dr Aldous was appointed as a Lecturer at UNSW in 2011.
Current Research Activities Biomass and Ionic Liquids: Dissolution and conversion of biomass into sustainable chemical source
Electroanalysis, with emphasis on nanomaterials and biomass
Energy, especially thermoelectrochemical devices.
Selected Publications “Electrochemistry of chloride in ambient room temperature ionic liquids: Formation of oxychloride species” M. M. Hossain; E. Hosseini Bab Anari; L. Aldous, Electrochemistry Communications 2013, 34, 331-334.
“Ionic Liquids for Lignin Processing: Dissolution, Isolation, and Conversion” M. M. Hossain; L. Aldous, Australian Journal of Chemistry 2012, 65, 1465-1477.
“Clean, efficient electrolysis of formic acid via formation of eutectic, ionic mixtures with ammonium formate” L. Aldous; R. G. Compton, Energy & Environmental Science 2010, 3(10), 1587-1592.
“Towards Mixed Fuels: The Electrochemistry of Hydrazine in the Presence of Methanol and Formic Acid” L. Aldous; R. G. Compton, ChemPhysChem 2011, 12(7), 1280-1287.
“The electrochemistry of quinizarin revealed through its mediated reduction of oxygen” Batchelor-McAuley, C.; Dimov, I. B.; L. Aldous; R. G. Compton, Proceedings of the National Academy of Sciences of the United States of America 2011, 108(50), 19891-19895.
Professional Activities International Society of Electrochemistry (member).
Electrochemistry Society (member).
Royal Society of Chemistry (member).
Royal Australian Chemical Institute (member).
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Dr Graham Edwin Ball B.Sc., Ph.D. Sheffield
Born in 1965, Dr Ball completed his Undergraduate and Postgraduate work at the University of Sheffield gaining his B.Sc. (1986) and Ph.D. (1990). He became a Postdoctoral Fellow at the University of British Columbia (1990-91), and then at the University of California, Berkeley (1991-1994). Dr Ball was appointed UNSW NMR Facility Manager and Adjunct Lecturer in 1995 and Senior Lecturer in 2005.
Current Research Activities Chemical and biological applications of NMR spectroscopy
Characterisation of reactive intermediates, specifically in organometallics
Computational chemistry Investigations of drug-DNA interactions
Structure elucidation Selected Publications Young, R.D.; Lawes, D.J.; Hill, A.F.; Ball, G.E. “Observation of a tungsten alkane σ-complex showing selective binding of methyl groups using FTIR and NMR spectroscopies” J. Am. Chem. Soc., 2012, 134, 8294– 8297.
Young, R.D.; Hill, A.F.; Hillier, W.; Ball, G.E. “Transition MetalAlkane σ-Complexes with Oxygen Donor Co-ligands” J. Am. Chem. Soc., 2011, 133, 13806-13809.
Ball, G.E.; Brookes, C.M.; Cowan, A.J.; Darwish, T.A; George, M.W.;. Kawanami, H.K.; Portius, P.; Rourke, J.P. “A delicate balance of complexation vs. activation of alkanes: NMR and TRIR studies of the interaction of alkanes with [Re(Cp)(CO)(PF3)].” Proc. Natl. Acad. Sci. USA., 2007, 104, 6927.
Ball, G.E.; Darwish, T.A; Geftakis, S.; George, M.W.; Lawes, D.J.; Portius, P.; Rourke, J.P. “Characterization of an Organometallic Xenon Complex using NMR and IR Spectroscopy.” Proc. Natl. Acad. Sci. USA., 2005, 102, 1853.
Geftakis, S.; Ball, G.E. “Direct Observation of a Transition Metal Alkane Complex, CpRe(CO)2(cyclopentane), Using NMR Spectroscopy,” J. Am. Chem. Soc., 1998, 120, 9953.
Professional Activities RACI Inorganic Division, NSW Representative.
Invited Lectures, Conference and Media Presentations Oral presentation, ANZMAG2013, Brisbane, October 2013
Oral presentation, 23rd Reactive Organometallics Symposium, Canberra, June 2013
academic staff / 13
Dr Jonathon Beves B.Sc. (Hons), USyd, Ph. D Basel
Dr Beves completed his BSc (Hons I) at the University of Sydney; PhD at the University of Basel (Switzerland, 2005-2008). He was a Swiss National Science Foundation Fellow at the University of Edinburgh (UK, 2009-2012), and a Research Associate Professor at Nanjing University (2012). Dr Beves was appointed as Lecturer at UNSW in 2013.
Current Research Activities
Professional Activities
Supramolecular Chemistry
Member of Royal Australian
Coordination Chemistry Molecular recognition Selected Publications J. E. Beves, V. Blanco, B. A. Blight, R. Carrillo, D. M. D’Souza; D. Howgego, D. A. Leigh, A. M. Z. Slawin, M. Symes, “Towards Metal Complexes that can Directionally Walk Along Tracks: Controlled Stepping of a Molecular Biped with a Palladium(II) Foot”, J. Am. Chem. Soc., 2014, DOI: 10.1021/ja4123973.
J. Yang, J. K. Clegg, Q. Jiang, X. Lui, H. Yan, W. Zhong, J. E. Beves, “Multipyridine decorated Fe(II) and Ru(II) complexes by Pd(0)-catalysed cross couplings: new building blocks for metallosupramolecular assemblies”, Dalton Trans. 2013, 42, 1562515636.
J. E. Beves, C. J. Campbell, D. A. Leigh, R. G. Pritchard, “Tetrameric Cyclic Double Helicates as a Scaffold for a Molecular Solomon Link”, Angew. Chem. Int. Ed., 2013, 52, 6464-6467.
J.-F. Ayme, J. E. Beves, D. A. Leigh, R. T. McBurney, D. Schultz, “A molecular pentafoil knot”, Nature Chem., 2012, 4, 15.
J. E. Beves, B. A. Blight, D. A. Leigh, R. T. McBurney, “Strategies and tactics for the metal-template synthesis of catenanes, rotaxanes, knots and links,” Angew. Chem. Int. Ed., 2011, 50, 9260-9327
Chemical Institute, Royal Society of Chemistry, Swiss Chemical Society
Referee for Chemical Science, Chemical Reviews, CrystEngComm, Crystal Growth & Design, Physical Chemistry Chemical Physics, Polyhedron, RSC Advances, Tetrahedron Letters.
Website content coordinator for School of Chemistry
Member, Hazardous Goods and Dangerous Materials Business Action Group.
Invited Lectures, Conference and Media Presentations
Departmental Seminar, University of Queensland, Metal template routes to molecular knots, links and cages 19 August 2013.
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Professor David St Clair Black M.Sc. Syd., Ph.D. Camb., AMusA, CChem, FRACI
Born in 1938, Professor Black completed his postgraduate work at the University of Sydney (MSc, 1960) and then at the University of Cambridge (PhD, 1963). He was a Post Doctoral Research Associate at Columbia University (1963 – 1964). He was appointed as Lecturer at Monash University (1965), promoted to Senior Lecturer (1971) and Reader in Organic Chemistry (1975). He was appointed Professor of Organic Chemistry at UNSW in 1983.
Current Research Activities Synthetic organic chemistry including methods of synthesis, heterocyclic chemistry (especially indole chemistry), photochemistry.
Organic aspects of coordination chemistry including ligand design and synthesis, macrocycles, organometallic chemistry.
Polymer chemistry - new polyamides, polyesters and modified peptides. Self-assembly studies involving hydrogen bonding.
Development of mild and efficient new metal complex catalysts related to Green Chemistry.
Natural products chemistry constituents of Endiandra and Beilschmiedia species, indole alkaloids.
Selected Publications Black, D. St.C., Editor, Science of Synthesis, Volume 15, Hetarenes and related ring systems: sixmembered hetarenes with one nitrogen or phosphorus atom, pub. Thieme Verlag, Stuttgart, 1320 pp (2004).
Wahyuningsih, T. D., Kumar, N. and Black, D. StC., Synthesis of indolo[2,3-c]quinolines from 3-arylindole-2-ketoximes, Tetrahedron, 63, 6713-6719 (2007).
Cheah, W. C., Black, D. StC., Goh, W. K. and Kumar, N., Synthesis of antibacterial peptidomimetics derived from N-acylisatins, Tetrahedron Letters, 49, 2965-2968 (2008).
Chen, R., Bhadbhade, M., Kumar, N and Black, D. StC., Synthesis of cyclic tetraindolyls via oxidative coupling reactions, Tetrahedron Letters, 53, 33373341 (2012).
Somphol, K., Chen, R., Bhadbhade, M., Kumar, N. and Black, D. StC., A new strategy for calixindole formation: synthesis of a calix[3]indole with 2,2; 7,2; 7,7-methylene linkages and a new calix[4]indole with 2,2; 7,2; 7,7; 2,7-methylene linkages, Synlett, 24-28 (2013).
Professional Activities Secretary General, IUPAC (20042011)
Secretary General, ICSU (20112014)
External Examiner, University of Malaya, Kuala Lumpur, Malaysia
Member of National Committee for Chemistry
Member of NMI Reference Materials Review Committee, National Measurement Institute, Australian Government Analytical Laboratory.
Invited Lectures, Conference and Media Presentations
The Role of the International Council for Science in Science Policy Advice, Symposium on Science and Policy Advice, Danish Academy, Copenhagen, 5 September 2013.
academic staff / 15
Associate Professor Stephen Boyd Colbran B.Sc, Ph.D Otago
Associate Professor Colbran gained his Ph.D from the University of Otago, New Zealand, in 1984. He then undertook post-doctoral research with Professor the Lord Jack Lewis, FRS, and Professor Brian Johnson, FRS, at the University Chemical Laboratories, University of Cambridge, England, 1984–1987. Steve was appointed to the academic staff of UNSW in 1987, and he spent 1994 on leave from UNSW as a Visiting Scientist in the Department of Chemistry, Massachusetts Institute of Technology, USA.
Current Research Activities Transition metal chemistry with an emphasis on:
Biological catalysis: using computational and synthetic models to understand multielectron redox processes in biology.
Biomimetic catalysis for a sustainable future: using biomimcry to prepare sophisticated catalysts for multielectron reduction/oxidation processes.
Electrochemistry and spectroelectrochemistry applied to transition metal systems.
Selected Publications McSkimming, A.; Bhadbhade, M. M.; Ball, G. E.; Colbran S. B., Rhodium complexes of a chelating ligand with imidazol2-ylidene and pyridin-2-ylidene donors: the effect of C-metalation of nicotinamide groups on uptake of hydride ion, Inorganic Chemistry, 2012, 51, 2191–2203.
McSkimming, A.; Bhadbhade, M. M.; Colbran S. B., Hydride ioncarrier ability in Rh(I) complexes of a nicotinamide-functionalised N-heterocyclic carbene ligand, Dalton Transactions, 2010, 39, 10581–10584.
Rawling, T.; Austin, C.; Buchholz, F.; Colbran S .B.; McDonagh A. M., Ruthenium phthalocyaninebipyridyl dyads as sensitizers for dye-sensitized solar cells: Dye coverage versus molecular efficiency, Inorganic Chemistry, 2009, 48, 3215–3227.
Moberg, V.; Mottaqlib, A. M.; Sauer, D.; Poplavskaya, Y.; Craig, D. C.; Deeming, A. J.; Colbran, S. B.; Nordlander, E., Chiral and achiral phosphine derivatives of alkylidyne tricobalt carbonyl clusters as catalysts for (asymmetric) inter- and intra-molecular Pauson-Khand reactions, Dalton Transactions, 2008, 2442–2453.
Lonnon, D. G. Lee, S.-T.; Colbran S. B., Valence tautomerism and coordinative lability in copper(II)– imidazolyl–semiquinonate anion models for the CuB centre in cytochrome c oxidase, Journal of the American Chemical Society, 2007, 129, 5800-5801.
Professional Activities Coordinator of Upper-level Laboratory Teaching for the School of Chemistry, UNSW
Member of the Society of Biological Inorganic Chemistry (SBIC), the American Chemical Society (ACS) and the Royal Australian Chemistry Institute (ACS)
ARC assessor for ARC Grant applications
Referee for the journals: Journal of the American Chemical Society; Chemistry–A European Journal; Journal of Physical Chemistry B, Inorganic Chemistry; Organometallics; Dalton Transactions; European Journal of Inorganic Chemistry; Inorganica Chimica Acta; Chemical Reviews.
Editorial Board Member for the International Journal of Inorganic Chemistry (IJIC) and for the Journal of Chemical Sciences (JChem).
Invited Lectures, Conference and Media Presentations Colbran group research results were highlighted in the UNSW Press Release http://newsroom. unsw.edu.au/news/science/ catalyst-teacup-new-approachchemical-reduction (Google finds ~59,000 webpages citing this press release) and in the June 2013 issue of Chemistry in Australia (published by the RACI) on page 7.
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Associate Professor Marcus Lawford Cole B.Sc (Hons) Ph.D Cardiff
BSc (Hons I) (Medal) 1998, PhD 2001, Cardiff University. Royal Society and ARC Postoctoral Fellow, Monash University 2002-3. Risdon-Grimwade Lecturer, University of Melbourne 2003. Lecturer and senior lecturer, University of Adelaide 2004-7. NSW Young Tall Poppy Science Award 2009. RACI Organometallic Chemistry Award in 2010.
Current Research Activities Low oxidation state and hydrido complexes of the p- and f-block elements. Catalytic applications of N-heterocyclic carbenes. Probe design for the investigation of ligand stereoelectronics.
Dunn, MD; Cole, ML; Harper, JB: Effects of an ionic liquid solvent on the synthesis of gamma-butyrolactones by conjugate addition using NHC organocatalysts, RSC Advances, 2012, 2, 1016010162.
Use of social media in large class teaching.
Gyton, MR; Cole, ML; Harper, JB: Ionic liquid effects on Mizoroki-Heck reactions: more than just carbene formation, Chem. Commun., 2011, 47, 9200-9202.
Selected Publications
Professional Activities
Cole, ML; Deacon, GB; Junk, PC; Konstas, K; Wang, J, Bittig, H; Werner, D: Synthesis, Structures and Reactivity of Lanthanoid(II) Formamidinates of Varying Steric Bulk, Chem. Eur J., 2013, 19, 1410-1420.
Secretary, Inorganic Division of the Royal Australian Chemical Institute.
Sterically hindered ligand design.
Cole, ML; Hibbert, DB; Kehoe, EJ: Students’ Perceptions of Using Twitter To Interact with the Instructor during Lectures for a Large-Enrollment Chemistry Course, J. Chem. Ed., 2013, 90, 671-672. Cole, ML; Deacon, GB; Junk, PC; Wang, J: Bulky Formamidinate-Supported Lanthanoid Halides and Alkyls, Including a Rare Terminal La− Me Species, Organometallics, 2013, 32, 1370-1378.
Fellow of Royal Australian Chemical Institute.
academic staff / 17
Dr William Alex Donald B.Sc Seattle, Ph.D UCLA Berkley
Born in 1983, Dr. Donald gained a B.Sc. from Seattle University in 2005, and his PhD from the University of California, Berkeley in 2010. He was awarded the IUPAC Prize for Young Chemists in 2011 and became the University of Melbourne Centenary Research Fellow from 2011-2012. In 2013 the Australian Research Council awarded him a Discovery Early Career Researcher Award, and he also joined UNSW as a lecturer.
Current Research Activities Obtaining a molecular level understanding of complex reaction mechanisms using mass spectrometry, laser spectroscopy, and electronic structure calculations. Directly probing reaction intermediates that are involved in many chemical processes, such as in energy production, organic synthesis, and heterogeneous and biological catalysis.
Developing methods to control the ionization and fragmentation of molecules to improve the analytical performance of many types of mass spectrometry analyses. This is being achieved by surface modification and by improving our fundamental understanding of electrospray ionization..
Selected Publications M.G. Leeming, J.M. White, R.A. J. O’Hair, W.A. Donald,* Mobile proton triggered radical fragmentation of nitroarginine containing peptides, Journal of the American Society for Mass Spectrometry (2014) DOI: 10.1007/s13361-013-0794-7.
W.A. Donald, C.J. McKenzie, R.A. J. O’Hair, C–H Bond Activation of Methanol and Ethanol by a High-Spin FeIVO Biomimetic Complex, Angewandte Chemie International Edition (2011) 50, 8379.
W. A. Donald, R. D. Leib, M. Demireva, E. R. Williams, Ions in Size-Selected Aqueous Nanodrops: Sequential Water Molecule Binding Energies and Effects of Water on Ion Fluorescence, Journal of the American Chemical Society (2011) 133, 18940.
W. A. Donald, R. D. Leib, M. Demireva, B. Negru, D. M. Neumark, E. R. Williams, “Weighing” Photon Energies with Mass Spectrometry: Effects of Water on Ion Fluorescence, Journal of the American Chemical Society (2010) 132, 6904.
W. A. Donald, M. Demireva, R. D. Leib, M. J. Aiken, E. R. Williams, Electron Hydration and Ion– Electron Pairs in Water Clusters Containing Trivalent Metal Ions, Journal of the American Chemical Society (2010) 132, 4633
Professional Activities Chartered member, Royal Australian Chemical Society
Member, Australian and New Zealand Society for Mass Spectrometry
Member, American Chemical Society
Member, American Society for Mass Spectrometry
Invited Lectures, Conference and Media Presentations Keynote presentation: Electrochemistry and photochemistry in mass spectrometry, Inorganic Chemistry Divisional Conference (IC’13), Brisbane, December 8-12, 2013
Invited seminar: Breaking the maximum charge state limit for protein ions formed in electrospray ionization, School of Chemistry, University of Wollongong, September, 2013
Invited presentation: Tracking the downstream metabolites of drugs and pesticides in vivo by twin ion metabolite extraction mass spectrometry, Recycling rocks: Understanding sustainability in a dynamic earth, Melbourne, July 15-16, 2013
Awards NSW Fresh Science Finalist, 2013
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Dr Gavin Leslie Edwards B.Sc, Ph. D Monash
Born in 1960, Dr Edwards completed his PhD studies at Monash University with Dr (now Professor) Glen Deacon and Professor David St Clair Black. He then undertook postdoctoral research at Imperial College, London, with Dr (now Professor) Willie Motherwell from 19871989. Dr Edwards was appointed as a Lecturer at UNSW in 1990 and Senior Lecturer in 1999. He is currently the Director of Teaching in the School of Chemistry. In 2011 he also took on the role of Associate Dean (Undergraduate Programs) in the Faculty of Science.
Current Research Activities
Professional Activities
Synthesis of novel DNA binding
Director of Teaching- School of
agents: new bisintercalating threading molecules, and organometallic drugs
Sulfones, sulfoxides and sulfoximines in organic synthesis
Cyclometallated complexes as new catalysts
Selected Publications Beeren, S.R., Dabb, S.L., Edwards, G., Smith, M.K., Willis, A.C., and Messerle, B.A., Improving Intramolecular Hydroamination Rh(I) and Ir(I) Catalysts Through Targeted Ligand Modification, New J. Chem., 2010, 34 1200-1208.
Edwards, G.L., Sinclair, D.J. “Sequential cyclosulfonylation and alkylation as a versatile strategy for dihydropyran synthesis.” Synthesis, 2005, 3613-3619.
Edwards, G.L., Black, D,St.C., Deacon, G.B., Wakelin, L.P.G. “In vitro and in vivo studies of neutral cyclometallated complexes against murine leukaemias.” Can. J. Chem. 2005, 83, 980-989.
Edwards, G.L., Black, D,St.C., Deacon, G.B., Wakelin, L.P.G. “Effect of charge and surface area on the cytotoxicity of cationic metallointercalation reagents.” Can. J. Chem. 2005, 83, 969-979.
Chemistry
Member: School of Chemistry Executive Committee
Member: Faculty of Science Education Committee
Member: Faculty of Science Standing Committee
Member: Faculty of Science International Committee
Member: School of Chemistry Executive
Member: School Visiting Committee
Member: Faculty of Engineering Education Committee
Member: UNSW Enrolment and Admissions Management Committee
Member: UNSW Early Intervention and Retention Reference Group
Member: UNSW Student Safety and Wellbeing Committee
Member: Governance Group of the Academic IT Business Domain
Member: Pre-University and Alternative Education Committee
Member: Advisory Board of Organic Preparations and Procedures International
academic staff / 19
Professor Leslie D. Field Ph.D., D.Sc. USyd
Ph.D. 1979 University of Sydney; D.Sc. 1991 University of Sydney; Postdoctoral Fellow, University of Southern California, Los Angeles, California, USA 1979-1981; Research Fellow, Oxford University, UK, 1981-1982; 1982-2005 Lecturer/Senior Lecturer/Reader/Professor University of Sydney; Professor of Organic Chemistry at the University of Sydney 1990 to 2005 and Head of the School of Chemistry from 1997 to 2001; Associate Dean for Research in the Faculty of Science, Chair of the University Research Committee, Deputy Chair of the Academic Board and Acting Pro-Vice-Chancellor (Research) at the University of Sydney. Vice-President & Deputy Vice-Chancellor (Research) at UNSW from April 2005.
Current Research Activities Organometallic chemistry of coordinated dinitrogen - nitrogen fixation.
C-H Bond activation and functionalisation
Organometallic chemistry of carbon dioxide
Applications of NMR spectroscopy in organic & organometallic chemistry
Transition metal catalysis in organic synthesis
Transition metal acetylides, organometallic polymers and new materials
Metallocene chemistry Selected Publications Bott, G.; Field, L. D.; Sternhell, S., Steric Effects - a Study of a Rationally Designed System. J. Am. Chem. Soc. 1980, 102 (17), 5618-5626.
Baker, M. V.; Field, L. D., Reaction of sp2 C-H Bonds in Unactivated Alkenes with Bis(Diphosphine) Complexes of Iron. J. Am. Chem. Soc. 1986, 108 (23), 7433-7434.
Baker, M. V.; Field, L. D., Reaction of Ethylene with a Coordinatively Unsaturated Iron Complex, Fe(depe)2 - sp2 C-H Bond Activation without Prior
Formation of a p-Complex. J. Am. Chem. Soc. 1986, 108 (23), 7436-7438.
Field, L. D.; Turnbull, A. J.; Turner, P., Acetylide-bridged organometallic oligomers via the photochemical metathesis of methyl-iron(II) complexes. J. Am. Chem. Soc. 2002, 124 (14), 3692‑3702.
Field, L. D.; Li, H. L.; Dalgarno, S. J.; Turner, P., The first side-on bound metal complex of diazene, HN=NH. Chem. Commun. 2008, (14), 1680-1682.
Professional Activities Fellow of the Australian Academy of Science
Fellow of the Royal Australian Chemical Institute
Member of the American Chemical Society
Member of the International Society for Magnetic Resonance
Journal Reviewer: Organometallics, Inorganic Chemistry, Dalton Transactions, Journal of the American Chemical Society, Nature Chemistry, Journal of Organometallic Chemistry, Chemical Communications
Australian Research Council: Ozreader
Director and Chairman NewSouth Innovations Pty Ltd
Director Australian Technology Park Innovations Pty Ltd
Director Victor Chang Cardiac Research Institute
Director Uniseed UITT Pty Ltd Director Uniseed Management Pty Ltd
Director Spatial Information Systems Ltd (SISL)
Alternate Director of the Environmental Biotechnology CRC
National ICT Australia Ltd (NICTA) UNSW Member Representative
Board Member ARC Centre for Functional Nanomaterials Advisory Board
Member of the National Drug & Alcohol Research Centre (NDARC) Board of Management
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Scientia Professor John Justin Gooding B.Sc. (Hons) Melb., D.Phil. (Oxon), CChem, MRACI
Graduate of Oxford University (D. Phil., 1994). Postdoctoral Fellow, University of Cambridge, (1994-1996). Vice-Chancellor’s Postdoctoral Research Fellow, UNSW (1997-1998). Lecturer, Flinders University of South Australia (1998). Appointed Lecturer at UNSW (1999), Senior Lecturer (2002), Associate Professor (2006), Professor (2006), Scientia Professor (2011). NSW Young Tall Poppy Science Prize (2004), Alexander von Humboldt Fellowship (2005), University of Canterbury Erskine Fellow (2007), Royal Australian Chemical Institute (RACI) Analytical Chemistry Division Lloyd Smythe Medal (2007), Vice-Chancellors Teaching Award for Post-graduate Supervision (2008), Eureka Prize for Scientific Research (2009), ARC Australian Professorial Fellow (2010-2014), RACI H.G. Smith Medal (2011), RACI Electrochemistry Division R.H. Stokes Medal (2012), Royal Society of Chemistry Australasian Lecturer (2012), NSW Science and Engineering Award in Emerging Research (2013). Co-Director of the Australian Centre for NanoMedicine.
Current Research Activities Immunosensors for detection of protein analytes (with a US based biosensing company)
Porous silicon photonic crystals for biological imaging and disease diagnosis (with Dr Peter Reece, Physics UNSW and Dr. Katharina Gaus, Medicine UNSW).
Modified surfaces for controlling surface interactions with cells for biomaterials applications (with Dr. Katharina Gaus, Medicine UNSW).
Nanoparticle based biosensors labelling and detection in for medical diagnostics (with Professor Rose Amal, Chemical Engineering, UNSW).
Silicon quantum dots for biolabelling (with the Australian Centre for NanoMedicine).
Detection of microRNA (with Prof. Maria Kavallaris, Australian Centre for NanoMedicine).
The three dimensional printing of cells (with Australian Centre for NanoMedicine).
The immobilisation of homogeneous catalyst on surfaces (led by Professor Barbara Messerle, Chemistry UNSW).
Selected Publications Gooding JJ, Wibowo R, Liu J, Yang W, Losic D, Orbons S, Mearns FJ, Shapter JG, Hibbert DB, Protein Electrochemistry using Aligned Carbon Nanotube Arrays, J. Am. Chem. Soc. 125, 9006-9007 (2003).
K.A. Kilian, L.M.H. Lai, A. Magenau, S. Cartland, T. Böcking, N. Di Girolamo, M. Gal, K. Gaus, J.J. Gooding, Smart Tissue Culture: In Situ Monitoring of Cellular Secretion With Nanostructured Photonic Crystals NanoLett. 9 2021-2025 (2009).
D.J. Williamson, D.M. Owen, J. Rossy, M. Wehrmann, A. Magenau, J.J. Gooding, K. Gaus, Pre-existing LAT clusters do not participate in early T cell signaling events, Nature Immunology 12 655-662 (2011).
P.K. Eggers, N. Darwish, M.N. Paddon-Row, J.J. Gooding, Surface-Bound Molecular Rulers
for Probing the Electrical Double Layer, J. Am. Chem. Soc. 134 7539-7544 (2012).
L.M.H. Lai, I.Y. Goon, K. Chuah, M. Lim, F. Braet, R. Amal, J.J. Gooding, Biochemiresistor Sensor– A New Type of Biosensor Employing Magnetic Assembly of Gold Coated Magnetic Nanoparticles, Angew. Chem. Int. Ed. 51 6456-6459 (2012).
Professional Activities Co-Director of the Australian Centre for NanoMedicine
Fellow of the RACI and PastChair of the Electrochemistry Division of the RACI
Vice President of The International Society of Electrochemistry
Handling editor for Journal of Chemical and Biological Interfaces. Member of the editorial board of the journals Electrochemistry Communications, Electroanalysis, Sensors, Nanobiotechnology, Sensors and Actuators B, Sensor Letters, Journal of
academic staff / 21
Nanoeducation, Analyst, Chemical Sciences, Biosensors
Member of the University Professorial Promotions Committee, School Advisory Committee, Post-Graduate Research Student Committee, Analytical Centre Solid State Advisory Group and Australian National Fabrication Facility UNSW node access committee.
Referee for the journals Nature Materials, Nature Nanotechnology, Journal of the American Chemical Society, Analytical Chemistry, Langmuir, Journal of Physical Chemistry B., Electroanalysis, Electrochemistry Communications, Talanta, IEEE Transactions on Biomedical Engineering, Sensors, Australian Journal of Chemistry, Analytical and Bioanalytical Chemistry, Biosensors Bioelectronics, Nucleic Acids Research, The Analyst, Chemical Communications, Journal of Immunological Methods, Journal of Material Science.
Referee for grant applications for the Refereed Grants for ARC, City University Research Grant Program, Hong Kong, A*star Singapore, NSERC, Canada.
Consultant for AgaMatrix Inc. and Inventia Pty Ltd
Invited Lectures, Conference and Media Presentations Nanomaterial Based Biosensors for Diagnostics and Personalised Medicine School of Medical Sciences, UNSW, Sydney 23 October 2013
Nanoparticle Based Biosensors for Diagnostics and Personalised Medicine
Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao, China, 17th October 2013
Nanoparticle Based Biosensors for Diagnostics and Personalised Medicine School of Chemistry, Chemical and Environmental Engineering, Laboratory of Fiber Materials and Modern Textile, the Growing Base for State Key Laboratory, Qingdao University, Qingdao, China, 16th October 2013
Nanotechnology and biosensors: From detecting small molecules to monitoring the activity of whole cells Institute of Glycomics, Griffith University, Gold Coast Campus, Australia, 3rd May 2013
Nanotechnology and biosensors: From detecting small molecules to monitoring the activity of whole cells, Eskitis Institute, Griffith University, Nathan Campus, Australia, 2nd May 2013
Making Silicon Water Friendly for Biosensing, Cell Biology and Molecular Electronic Applications, Institute for Analytical and Bioanalytical Chemistry, Ulm University, Germany, 15th March 2013
Biosensors: The Benefits of Nanotechnology, School of Chemistry, University of Geneva, Switzerland 7th March 2013
Cell Chips: Nanostructured Materials That Can Report On The Release Of Matrix Metalloproteases From Just A Few Cells, 12th International Conference on Frontiers of Polymers and Advanced Materials, Auckland, New Zealand, 8-14 Dec 2013. Keynote speaker
Designing and Characterising Bioaffinity Surfaces for Sensing, 40th International Symposium on High Performance Liquid Phase Separations and Related Techniques 2013, Hobart, 18-21 November 2013, Plenary lecture
From home use diagnostics to targeted drug delivery, AusBiotech 2013, Brisbane, 30 Oct-1 Nov 2013.
Nanoparticle Based Biosensors for Diagnostics and Personalised Medicine, Taishan Academic Forum on Life-Organic Analysis and Nano-Chemistry (TAFLOAN), Qufu, China 18-20 October 2013. Keynote speaker
Nanostructured Materials that can Report on the Release of Matrix Metalloproteases From Just a Few Cells, COmBio2013, Perth Australia 29 Sept-3 Oct 2013.
Surface-Bound Peptides for Biosensing and Cell Biology, 10th Australian Peptide Conference, Penang, Malaysia, 8-13 September 2013
Making Silicon Water Friendly for Biosensing and Biolabelling Applications, 87th ACS Colloid and Surface Science Symposium, Riverside, California 23-26 June 2013.
Electrodes that resist protein fouling when used in biological fluids: Applications for biosensing, cell biology and implantable
electrodes, XIX Brazilian Symposium of Electrochemistry and Electroanalytical Chemistry, Campos do Jordão, Sao Paulo, Brazil, 1-5 April 2013. Plenary lecture
Electrodes that resist protein fouling when used in biological fluids: Applications for biosensing, cell biology and implantable electrodes, Bioelectrochemistry 2013, 12th Topical Meeting of the International Society of Electrochemistry, Bochum, Germany, 17-21 March 2013. Plenary lecture.
Awards 2013 New South Wales Science and Engineering Award for Emerging Research.
Finalist: 2013 Eureka Prize for Interdisciplinary Science.
Listed in The Analytical Scientist magazine as one of the top 100 most influential analytical scientists worldwide in 2013.
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Dr Ronald Stanley Haines B.Sc. (Hons 1, University Medal), Ph.D. UNSW
B.Sc. in Pure and Applied Chemistry and Ph.D. at UNSW. Postdoctoral Research Associate with Prof. B.J. Orr, UNSW, 1982-1983; Senior Tutor, School of Chemistry, UNSW 1983-1989; Principal Tutor, School of Chemistry, UNSW 1989-1992; Lecturer in Physical Chemistry, UNSW 1992-present. First Year Laboratory Coordinator, 2008 - present.
Current Research Activities Chemical education and the impact of mobile devices and web development technologies on content delivery. Chemical kinetics, in particular the influence on reaction mechanisms of ionic liquids as solvents. Selected Publications Bogaard M.P., Haines R., Raman Intensities and Cartesian Polarizability Derivatives, Mol. Phys, 41(6), 1980, 1281-1289 Duval A.B., King D.A., Haines R., Isenor N.R., Orr B.J., Coherent Raman Spectroscopy of Glyoxal Vapour, Journal of Raman Spectroscopy, 17(2), 1986, 177-182 Haines R, Teaching Computer Concepts to Undergraduate Chemists, J. Chem. Educ., 1998, 75, 785-787 Haines R.S., Woo, D.T., Hudson, B.T., Mori, J.C., Ngan, E.S.M., Pak, W-Y Interdisciplinary Educational Collaborations: Chemistry and Computer Science, J. Chem. Educ., 2007, 84, 967-970
Haines, R.S., Wu, A.H.F., Lamb, R., Hua Zhang, Coffey, J., Huddle, T., Lafountaine, J.S., Lim, Zhi-Jun, White, E.A. and Tuong, N.T., SelfCleaning Surfaces: A Senior Undergraduate Research Project, J. Chem. Educ. 2009, 365-367 Professional Activities First Year Chemistry Laboratory Coordinator School of Chemistry IT Coordinator. Member, School of Chemistry Teaching Committee Member, Faculty of Science IT Committee. Chair Honours Thesis Reading Panel D
academic staff / 23
Dr Jason Brian Harper B.Sc. Adel., B.Sc. (Hons), Ph.D. ANU
Born 1974. Undergraduate work carried out at the University of Adelaide (B.Sc. 1995) and in The Faculties, Australian National University (B.Sc. (Hons) 1996). Shell Australia Postgraduate Scholar, Research School of Chemistry, Australian National University (Ph.D. 2000). C.J. Martin Postdoctoral Fellow, University Chemical Laboratory, Cambridge (2000-2002). Associate Lecturer, The Open University in East Anglia (2001). Appointed to the School of Chemistry, UNSW as Lecturer in 2002 and Senior Lecturer in 2007. SSP at Boston College (2009).
Current Research Activities Application of physical organic chemistry to understanding organic processes, including:
The development of an understanding of ionic liquids as novel reaction media, and their application.
The examination of the chemical and physical properties N-heterocyclic carbenes, particularly those based on ionic liquid cations (in collaboration with Assoc. Prof. Marcus Cole, School of Chemistry, UNSW)
The investigation of novel NMR spectroscopic methods for monitoring reaction kinetics (in collaboration with Dr James Hook, UNSW Analytical Centre).
Selected Publications Yau, H. M.; Keaveney, S. T.; Butler, B. J.; Tanner, E. E. L.; Guerry, Max S.; George, S. R. D.; Dunn, M. H.; Croft, A. K.; Harper, J. B.: “Towards solvent-controlled reactivity in ionic liquids” Pure Appl. Chem. 2013, 85, 1979-1990.
Tanner, E. E. L.; Yau, H. M.; Hawker, R. R.; Croft, A. K.; Harper, J. B.: “Does the cation really matter? The effect of modifying an ionic liquid cation on an SN2 process”, Org. Biomol. Chem. 2013, 11, 6170-6175.
Yau, H. M.; Croft, A. K.; Harper, J. B.: “One-Pot Hammett Plots: A General Method for the Rapid Aquisition of Relative Rate Data”, Chemical Communications 2012, 48, 8937-8939.
Yau, H. M.; Croft, A. K.; Harper, J. B.: “Investigating the origin of entropy-derived rate accelerations in ionic liquids”, Faraday Discussions 2012, 154, 365-371.
Gyton, M. R.; Cole, M. L.; Harper, J. B.: “Ionic liquid effects on Mizoroki-Heck reactions: More than just carbene complex formation”, Chemical Communications 2011, 47, 92009202.
Professional Activities Director, Faculty of Science Talented Students Programme
Deputy Director of Teaching, School of Chemistry
Co-Chair and Bid Developer, Local Organising Committee, 23rd IUPAC Conference on Physical Organic Chemistry (Sydney 2016)
Organising Committee, 2014 Australasian Symposium on Ionic Liquids / Asia-Pacific Symposium on Ionic Liquids
Treasurer, Southern Highlands Conference on Heterocyclic Chemistry
Member, Australian Chemistry Discipline Network
Member, Royal Australian Chemical Institute
Member, American Chemical Society (ACS)
Invited Lectures, Conference and Media Presentations Reaction outcomes in ionic liquids: How much do the components of the solvent matter? Invited Lecture, 6th Heron Island Conference on Reactive Intermediates and Unusual Molecules, Heron Island, QLD, Australia, 7th – 12th July 2013.
Getting the reaction outcomes you want in ionic liquids: Towards solvent-controlled reactivity. Invited Lecture, 6th International Conference on Green and Sustainable Chemistry, Nottingham, UK, 4th – 7th August 2013.
Invited lectures at: University of Nottingham University of Sydney Australian National University University of Melbourne CSIRO Molecular Science Monash University University of Western Sydney. Awards: Arc Postgraduate Council Award for Excellence in Postgraduate Supervision.
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Dr Luke Hunter B. Ad.Sc (Hon), Ph.D, USyd
Born in 1979, Dr Hunter completed his Undergraduate and Postgraduate work at The University of Sydney gaining his B. Ad.Sc (1999) and Ph. D (2004). He went on to Postdoctoral positions at The University of Melbourne (2005), The University of St Andrews (2005 – 2008), The University of NSW (2008 – 2009) and The University of Sydney (2009 – 2011). He was appointed Senior Lecturer at UNSW in 2011.
Current research Activities
RGD peptides for treatment of cancer
Yamamoto, I.; Jordan, M. J. T.; Gavande, N.; Doddareddy, M. R.; Chebib, M.; Hunter, L. “The enantiomers of syn-2,3difluoro-4-aminobutyric acid elicit opposite responses at the GABAC receptor,” Chemical Communications 2012, 48, 829.
Selected Publications
Professional Activities
Hunter, L.; Kirsch, P.; Slawin, A. M. Z.; O’Hagan, D., “Synthesis and structure of stereoisomeric multivicinal hexafluoroalkanes,” Angewandte Chemie International Edition 2009, 48, 5457.
MRACI CCHEM
Natural product total synthesis Fluorinated amino acids Cyclic peptides GABA receptor ligands
Cheerlavancha, R.; Lawer, A.; Cagnes, M.; Bhadbhade, M.; Hunter, L., “Sequential Deoxyfluorination Approach for the Synthesis of Protected a,β,γ-Trifluoro-δ-amino Acids,” Organic Letters 2013, 15, 5562. Hunter, L.; Chung, J. H., “Total synthesis of unguisin A,” Journal of Organic Chemistry 2011, 76, 5502. Hunter, L.; Jolliffe, K. A.; Jordan, M. J. T.; Jensen, P.; Macquart, R. B., “Synthesis and conformational analysis of α,β-difluoro-γ-amino acid derivatives,” Chemistry: A European Journal 2011, 17, 2340.
Treasurer, RACI NSW Branch Member, American Chemical Society Invited Lectures, Conference and Media Presentations Backbone-fluorinated amino acids: synthesis and applications, SynthCon2 Conference (Yarra Valley) Backbone-fluorinated amino acids: synthesis and applications, European Symposium on Fluorine Chemistry (Paris)
academic staff / 25
Professor Naresh Kumar M.Sc. Punj. Ph.D. W’gong., CChem, MRACI
A/Prof Naresh Kumar completed his PhD in organic chemistry at Wollongong University in 1983, and after working as a Research Scientist at the School of Chemistry, University of NSW was appointed a Lecturer in 2003. He moved through the ranks to become a full Professor in chemistry in 2013.
Current Research Activities Design and synthesis of quorumsensing inhibitors
Development of synthetic methodologies for the preparation of biologically important natural products and their analogues
Ho K K K, Chen R, Willcox MDP, Rice SA, Cole N, Iskander G, Kumar N, Quorum sensing inhibitory activities of surface immobilized antibacterial dihydropyrrolones via click chemistry, Biomaterials, 2014, 35, 2336-2345..
Novel antimicrobial biomaterials
Professional Activities
Heterocyclic chemistry
Internal
Calixarene chemistry
Academic in charge: B Med
Selected Publications Cheah WC, Wood K, Black DStC, and Kumar N, Facile ring-opening of N-acylisatins for the development of novel peptidomimetics. Tetrahedron 2011, 67, 7603-7610.
Devakaram R, Black DStC, Andrews KT, Fisher GM, Davis RA, Kumar N, Synthesis and antimalarial evaluation of novel benzopyrano[4,3-b]benzopyran derivatives. Bioorganic & Medicinal Chemistry, 2011,19, 5199-5206.
Kutty SK, Barraud N, Pham A, Iskander G, Rice SA, Black DStC, Kumar N, Design, Synthesis, and Evaluation of FimbrolideNitric Oxide Donor Hybrids as Antimicrobial Agents, Journal of Medicinal Chemistry, 2013, 56, 9517-9529.
Eugene MH, Pasqueir E, Iskander G, Black DStC, and Kumar N, Synthesis of novel isoflavenepropranolol hybrids as anti-tumor agents, Bioorganic &. Medicinal Chemistry, 2013, 21,1652-1660.
Chem program
Academic in charge: School of Chemistry Outreach program
Member: School of Chemistry Research Management Committee
Member: School of Chemistry Postgraduate Committee
Member: School of Chemistry Search Committee
Member: School of Chemistry Visiting Committee
External Member, Royal Australian Chemical Institute (RACI)
Member, American Chemical Society
Chair, RACI (NSW) Natural Products Chemistry Group 2013
Assessor for ARC Discovery and Linkage Projects
Assessor for ARC Future Fellowship applications
Reviewer for NHMRC Project Grant applications
Research project evaluation for King Fahd University of Petroleum and Minerals, Saudi Arabia
Reviewer for Academic Research Fund applications, Nanyang Technological University, Singapore
MSc and PhD thesis examiner for national and international universities
Referee for Tetrahedron Letters, Tetrahedron, Current Medicinal Chemistry, Synlett, Synthesis, Australian Journal of Chemistry, Bioorganic and Medicinal Chemistry, Journal of Organic Chemistry, Chirality, Journal of Medicinal Chemistry, Biofouling, and Acta Biomaterialia, RSC Advances.
Invited Lectures, Conference and Media Presentations Synthesis of novel biologically active scaffolds based on flavones and isoflavones, Oral presentation at the RACI 2013 Biomolecular Division Conference, Leura, 14-17 July 2013.
Synthesis of novel peptide mimics derived from N-acylisatins, Oral presentation at the Asian Chemical Congress, Singapore, 19-23 August 2013.
Bio-inspired development of antimicrobial compounds and coatings, Invited lecture at the School of Chemistry, University of Queensland, 11 November 2013.
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academic staff / 27
Associate Professor Shelli Renee McAlpine Ph. D. UCLA
Born in 1969, A/Prof. McAlpine was awarded her PhD from The University of California, Los Angeles, in 1997. She then spent three years as a Postdoctoral Researcher at Harvard University before being appointed as an Assistant Professor at San Diego State University in 2000. Shelli was promoted to Associate Professor in 2006 and Professor in 2010. In 2011 Shelli joined UNSW as an Associate Professor.
Current research Activities Development of new antibiotics Investigating Hsp90 inhibitors as potential chemotherapeutics
Synthesis and Mechanistic evaluation of natural products
Creating delivery methods for our biologically active molecules
Selected Publications A structure-activity relationship study on multi-heterocyclic molecules: two linked thiazoles are required for cytotoxic activity Seong Jong Kim, Chun Chieh Lin, Chung-Mao Pan, Dimple P. Rananaware, Deborah M. Ramsey, and Shelli R. McAlpine* Med. Chem. Comm. V4 , p406410, 2013
Mechanism of action for a novel macrocycle: a small molecule inhibitor of the ribosome machinery Worawan Tantisantisom, Deborah M. Ramsey, and Shelli R. McAlpine*Organic Letters V15, p4638-4641, 2013
Effectively delivering a drug using star polymers: Improving solubility of a unique hsp90 inhibitor Seong Jong Kim, Deborah M. Ramsey, Cyrille Boyer, Thomas Davis, and Shelli R. McAlpine* ACS Med. Chem. Lett V4, p915-920, 2013
Total synthesis and biological activity of the natural product Urukthapelstatin A Chun Chieh Lin, Worawan Tantisantisom, and Shelli R. McAlpine* Organic Letters V15, p3574-3577, 2013
Heat shock proteins 27, 40, and 70 as combinational therapeutic targets Jeanette R. McConnell and Shelli R. McAlpine* Bioorg. & Med. Chem. Lett. V23, p19231928, 2013
Professional Activities American Chemical Society: International committee member for Board Current
American Chemical Society: Member Executive comm. (Med Chem Division) Section Editor for Oncology for Annual Reports in Medicinal Chemistry
Advisory board member for “Current Topics in Medicinal Chemistry”
Editorial Board: Frontiers in chemical biology, Review Editor
RACI Biomolecular International Liason
RACI Congress- Committee Organizer
GRC Med Chem: organized session for GRS (graduate research students)
RACI Organic Symposium: organized a US speaker and funding
RACI Biomolecular Committee Organizer
Invited Lectures, Conference and Media Presentations Macrocyclic peptides: the perfect tools to explore protein function, Monash Institute of Pharmaceutical Sciences (MIPS) May, 2013
Macrocyclic molecules:diverse structures that range from heat shock protein inhibitors to ribosomal protein inhibitors, Walter and Eliza Hall Institute of Medical Research (WEHI), May 2013
Modulating Hsp90 using new tools: macrocycles that control Hsp90’s c-terminus, St Judes Cancer Center, Tennessee, April 2013
Macrocyclic compounds: the perfect tools to explore protein function, Vanderbuilt University (Chemistry and Pharmacology), April 2013
Macrocyclic peptides: the perfect tools to explore protein function, CSIRO (Melbourne), February 2013
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Professor Barbara Anne Messerle Ph. D. Syd
Ph.D. University of Sydney 1987. Postdoctoral Fellow ETH Zürich, Switzerland 1987-1989, Gritton Research Fellow, University of Sydney 1990-1991; ARC Queen Elizabeth II Fellow 1992-1997, and ARC Senior Research Fellow 1997-1998, at the University of Sydney. Appointed to UNSW as ARC Senior Research Fellow 1999-2002, Senior Lecturer 20022003, Associate Professor 2004-2007 and Professor 2008. Head of School 2007 - current.
Current Research Activities Enhancing the economic viability and the energy efficiency of chemical transformations is of fundamental importance in the chemicals industry. Organometallic catalysts are an increasingly important means of providing new and more efficient routes for chemical processes. Our research projects involve the design and synthesis of metal catalysts for:
the formation of C-X bonds in heterocycles (X=N,O,S)
the synthesis of amines via the hydrosilation and hydrogenation of imines.
Our projects also involve developing
surface supported catalysts for optimal recycling
novel bimetallic catalysts for enhancing catalyst efficiency
new approaches to catalysed multiple step reactions for the synthesis of amines and spiroketals
novel approaches to the immobilization of transition metal catalysts on surfaces
new methods using parallel synthesis for developing catalysts for multistep processes
Selected Publications Andrey A. Tregubov, Khuong Q. Vuong, Erwann Luais, J. Justin Gooding, and Barbara
A. Messerle* Rh(I) Complexes Bearing N,N and N,P Ligands Anchored on Glassy Carbon Electrodes: towards Recyclable Hydroamination Catalysts, Journal of the American Chemical Society, 2013, 135 (44), 16429–16437
Sandra W. S. Choy, Michael J. Page, Mohan Bhadbhade and Barbara A. Messerle*, Cooperative Catalysis: Large Rate Enhancements with Bimetallic Rhodium Complexes, Organometallics, 2013, 2013, 32 (17), 4726–4729.
Joanne Hui Hui Ho, Sandra Choy, Stuart Macgregor, Barbara A. Messerle “Cooperativity in Bimetallic Dihydroalkoxylation Catalysts built on Aromatic Scaffolds: Significant Rate Enhancements with a Rigid Anthracene Scaffold”, Organometallics, 2011, 30(21), 5978–5984.
Torstein Fjermestad, Joanne H. H. Ho, Stuart A. Macgregor, Barbara A. Messerle, and Deniz Tuna, Computational Study of the Mechanism of Cyclic Acetal Formation via the Iridium(I)-Catalyzed Double Hydroalkoxylation of 4-Pentyn-1ol with Methanol Organometallics, 2011, 30(3), 618-626. ERA ranking A*
Michael J. Page, Jörg Wagler, and Barbara A. Messerle “Pyrazolyl-N-Heterocyclic
Carbene Complexes of Rhodium as Hydrogenation Catalysts: The influence of Ligand Steric Bulk on Catalyst Activity”, Dalton Trans, 2009, 7029-7038
Professional Activities Head of School Chair of National NMR Steering committee (ANZMAGnet) for developing a National NMR Facility
Chair, University Committee on Management of Hazardous Materials and Dangerous Goods
Member, Selection committee for HOS, School of Materials Science and Engineering
Member, Judging Committee, UNSW Science Faculty Photo Competition
Patron, AdminNet, UNSW Mentor for the Academic Women in Leadership, Early Career Researcher UNSW programs
Reviewer, International Granting Agencies: ASTAR, Singapore, American Chemical Society Petroleum research fund, USA
Member, Asia Pacific NMR 2013 Scientific committee
Member, National Committee for the International Conference on Organometallic Chemistry (ICOMC), Melbourne in 2016
Journal Reviewer 2013: Angewandte Chemie, Dalton, Chemical Communications,
academic staff / 29
Organometallics, Inorganic Chemistry, Dalton, American Chemical Society Catalysis, Australian Journal of Chemistry
Invited Lectures, Conference and Media Presentations Multimetallic Catalysis for Efficient Heterocycle Synthesis: From Homogeneous to Supported Catalysts, RACI Inorganic Chemistry Divisional Conference (IC’13), Brisbane 8th-12th December 2013 (SL6D) oral presentation.
Multimetallic Catalysis: From Homogeneous to Heterogeneous Catalysts 5th Asia-Pacific NMR Symposium (APNMR5)/9th biennial meeting of the Australian & New Zealand Society for Magnetic Resonance (ANZMAG) Brisbane, Australia 27th-30th of October, 2013, Plenary lecture
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Associate Professor Jonathan Charles Morris B.Sc UWA, Ph.D ANU
A/Prof Morris obtained his B.Sc. (Hons) degree from the University of Western Australia. He completed his Ph.D. degree at the Australian National University in 1994. After a postdoctoral appointment at the University of Texas at Austin (1994-1996), he joined the faculty at the University of Canterbury, New Zealand. In 2004, he moved to the University of Adelaide. In late 2009, he was appointed as Associate Professor of Medicinal Chemistry at UNSW.
Current Research Activities Total synthesis of biologically active natural products
Design of inhibitors of kinases that regulate alternative splicing [with Prof D. Bates (Nottingham) and Prof S. Knapp (Oxford)]
Applications of the Diels-Alder reaction to the synthesis of biologically active molecules
Design of phosphatase activators (with Dr Anthony Don, Lowy Cancer Centre and Dr Nikki Verrills, University of Newcastle)
Medicinal chemistry (projects with Prof Peter White, BABS and the Centre of Vascular Research).
Selected Publications Anderson, R. J.; Hill, J. B.; Morris, J. C., Concise Total Syntheses of Variolin B and Deoxyvariolin B, J. Org. Chem., 2005, 70, 6204.
Bungard, C.J.; Morris, J.C., Total Synthesis of the 7,3’-Linked Naphthylisoquinoline Alkaloid Ancistrocladidine, J. Org. Chem., 2006, 71, 7354.
Collison, A.; Hatchwell, L.; Verrills, N.; Wark, P.A.B; de Siqueira, A.P.; Tooze, M.; Carpenter, H.; Don, A.S.; Morris, J.C.; Zimmermann, N.; Bartlett, N.W.; Rothenberg, M.E.; Johnston, S.L.; Foster, P.S.; Mattes, J. ‘The E3 ubiquitin ligase
midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity’, Nature Medicine, 2013, 19, 232.
Bettayeb, K.; Tirado, O. M.; Marionneau-Lambot, S.; Ferandin, Y.; Lozach, O.; Morris, J.C.; Mateo-Lozano, S.; Drückes, P.; Schächtele, C.; Kubbutat, M.; Liger, F.; Marquet, B.; Joseph, B.; Echalier, A.; Endicott, J.; Notario, V.; Meijer, L., Meriolins, a new class of cell deathinducing, cyclin-dependent kinase inhibitors with enhanced selectivity for CDK9, Cancer Research, 2007, 67, 8325-8334
Echalier, A.; Bettayeb, K.; Ferandin, Y.; Lozach, O.; Clement, M.; Valette, A.; Liger, F.; Marquet, B.; Morris, J.C.; Endicott, J.; Joseph, B.; Meijer, L., Synthesis, protein kinase inhibitory activity and cytotoxicity of 3-(pyrimidin4-yl)-7-azaindoles (meriolins). CDK2/cyclin A/meriolin and CDK2/cyclin A/variolin B crystal structures, J. Med. Chem. 2008, 51, 737.
Professional Activities Postgraduate Coordinator, School of Chemistry.
Member, School Advisory Committee, School of Chemistry, UNSW
Member, Research Committee, School of Chemistry, UNSW
Member, Faculty of Science Higher Degree Committee
Chair, RACI NSW Branch Organic Division One Day Symposium.
Member, Appointment Committee for the School of Psychology, UNSW.
Member, Royal Australian Chemical Institute and American Chemical Society.
Referee for ACS, RSC, Wiley and Elsevier Journals
Invited Lectures, Conference and Media Presentations “Taking the Lead From Nature: Using Organic Synthesis to Investigate Biological Problems”, The Australian National University, Canberra, 31 October
“Taking the Lead From Nature: Using Organic Synthesis to Investigate Biological Problems”, Monash University, Melbourne, 11 November
“Taking the Lead From Nature: Using Organic Synthesis to Investigate Biological Problems”, University of Queensland, Brisbane, 18 November
academic staff / 31
Dr Nicholas Kenneth Roberts B.Sc.(Hons) Ph.D. University of Western Australia
Born in 1952 Dr Roberts gained his BSc (Hons), 1973 and PhD, 1979, with Dr S. Bruce Wild, University of Western Australia. Post-doctoral research followed with Prof. Bryce Bosnich at Lash-Miller Laboratories, University of Toronto, Canada, between 1979 and 1981. Research Fellow, Australian National University with Professor Martin A. Bennett 1981 to 84. Appointed as a lecturer in the School of Chemistry, UNSW in 1984 and senior lecturer in 2005. Dr. Roberts is the current coordinator of first year classes. Dr Roberts retired from UNSW in July 2013
Current Research Activities Synthesis and Reactions of Volatile Zinc Carbamates for Chemical Vapour Deposition.
Synthesis and Reactions of Volatile Aluminium Carbamates for Chemical Vapour Deposition.
Selected Publications Petrella AJ, Deng H, Roberts NK, and Lamb RN, Single-source chemical vapor deposition growth of ZnO thin films using Zn4O(CO2NEt2)6, Chemistry of Materials 14 (10): 4339-4342 Oct 2002.
Heterobimetallic calix[4]arene complexes: Interconversion of dimeric (Ca, Sr or Ba)/TiIV complexes with a monomeric K/TiIV complex. Petrella, Antonella J.; Roberts, Nicholas K.; Raston, Colin L.; Craig, Donald C.; Thornton-Pett, Mark; Lamb, Robert N. European Journal of Inorganic Chemistry (2003), (23), 4153-4158.
A heterobimetallic K2Ti2 complex incorporating two calix[5]arenes: A diverse array of metal-ligand interplay. Petrella, Antonella J.; Roberts, Nicholas K.; Craig, Donald C.; Raston, Colin L.; Lamb, Robert N., Chemical Communications (2003), (14), 1728-1729.
Dialkylcarbamato magnesium cluster complexes: precursors to the single-source chemical vapour deposition of high quality MgO thin films. Hill MR, Jones AW, Russell JJ, Roberts NK, Lamb RN, Journal of Materials Chemistry, 14 (21): 31983202, 2004
Towards new precursors for ZnO thin films by single source CVD: the X-ray structures and precursor properties of zinc ketoacidoximates. Hill, MR; Jones, AW; Russell, JJ; Roberts, NK; Lamb, RN, Inorganica Chimica Acta (2005) 358(1): 201206.
Professional Activities Director of First Year Chemistry (January – July)
Member: Teaching Committee Member of the Royal Australian Chemical Society
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Dr Neeraj Sharma B.Sc. Ph.D, University Sydney
Dr Sharma completed his Undergraduate (2006) and Postgraduate (2010) work at the University of Sydney. He then became a postdoctoral researcher at the Bragg Institute, Australian Nuclear Science and Technology Organisation (ANSTO). Dr. Sharma was appointed as a Lecturer at UNSW in conjunction with an Australian Institute of Nuclear Science and Engineering (AINSE) Research Fellowship.
Current Research Activities Structural investigations of new materials using synchrotron X-ray and neutron scattering
In situ studies of materials functioning in real-life devices
Development of new ionic conductors
Selected Publications N. Sharma, D. Yu, Y. Zhu, Y. Wu, V. K. Peterson, Non-equilibrium structural evolution of the lithium rich Li1+yMn2O4 cathode within a battery, Chemistry of Materials, 25, 754–760 (2013)
W. Brant, S. Schmid, Q. Gu, G. Du, N. Sharma, A simple electrochemical cell for in-situ fundamental structural analysis using synchrotron X-ray powder diffraction, Journal of Power Sources, 244, 109-114 (2013)
N. Sharma, V. K. Peterson, Current dependency of lattice fluctuations and phase evolution of electrodes in lithium-ion batteries investigated by in situ neutron diffraction, Electrochimica Acta, 101, 79-85 (2013)
P. Serras, V. Palomares, J. Alonso, N. Sharma, J. M. Lopez del Amo, P. Kubiak, M. L. Fdez-Gubieda, T. Rojo, The electrochemical Na extraction/insertion of Na3V2O2x(PO4)2F3-2x, Chemistry of Materials, 25, 4917-4925 (2013)
C. D. Ling, S. A. Schmid, P. E. R. Blanchard, V. Petricek, G. J. McIntyre, N. Sharma, A. Maljuk, A. A. Yaremchenko, V. V. Kharton, M. J. Gutmann, R. L. Withers, A (3 + 3)-Dimensional “Hypercubic” Oxide-Ionic Conductor: Type II Bi2O3−Nb2O5, Journal of the American Chemical Society, 135, 6477-6484 (2013)
Professional Activities Seminar Coordinator, Chair of the UNSW Chemical Society
Secretary/Treasurer Materials Division, RACI
Member of the International Society of Electrochemistry, Royal Australian Chemical Institute, Society of Crystallographers in Australian and New Zealand, Australian X-Ray Analytical Association
Invited lectures, conference & media presentations “What neutron diffraction can tell us about lithium-ion battery materials?” 2nd International Symposium on Neutron Scattering, India, January 2013.
“Using time-resolved structural analysis to direct improvements in lithium-ion battery technology” 10th PACRIM, San Diego, USA, June 2013.
“How materials chemistry can solve our energy needs?” NSW Branch Meeting of Materials Australia, August 2013
Awards RACI Nyholm Lectureship NSW Tall Poppy Award
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Associate Professor John Arron Stride B.Sc. (Hons), Ph.D., University of E. Anglia, UK.
Dr. Stride obtained his B.Sc.(Hons.) in Chemistry in 1991 and a Ph.D. in 1996 from the University of East Anglia, UK. He then held Post-Doctoral Fellowships at the Hahn-Meitner Insitute, Germany, (1995-1998) and at the Laboratoire Léon Brillouin, France, (1998-2000) before taking on the role of instrument scientist in the Time-of-Flight Group at the Institute Laue-Langevin, France, (2000-2005). He moved to UNSW in 2005. In 2013 he was awarded a Vice-Chancellor’s Award for Excellence in Postgraduate Research Supervision.
Current Research Activities Molecular and low dimensional magnetism
Molecular dynamics and solid state structures
Inorganic functional materials Neutron scattering Nano-structured materials & graphene
Selected Publications A flexible copper based microporous metal-organic framework displaying selective adsorption of hydrogen over nitrogen. M.A. Nadeem, A.W. Thornton, M.R. Hill and J.A. Stride, Dalton Trans., 2011, 40, 3398.
Gram-scale production of graphene based on solvothermal synthesis and sonication. M. Choucair, P. Thordarson and J.A. Stride, Nat. Nanotechnol., 2009, 4, 30.
The central atom size effect on the structure of Group XIV tetratolyls. M.C.C. Ng, D.J. Craig, J.B. Harper, L. van-Eijck and J.A. Stride, Chemistry, Eur. J., 2009, 15, 6569.
Structure and dynamics of a discotic liquid crystalline charge transfer complex. O. Kruglova, E. Mendes, Z. Yildirim, M. Wübbenhorst, F.M. Mulder,
J.A. Stride, S.J. Picken and G.J. Kearley, ChemPhysChem., 2007, 8, 1338.
Symmetry and Topology Determine the MoV-CN-MnII Exchange Interactions in High Spin Molecules, E. Ruiz, G. Rajaraman, S. Alvarez, B. Gillon, J. Stride, R. Clérac, J. Larionova and S. Decurtins, Angew. Chem., Int. Ed, 2005, 44, 2711.
Professional Activities Director of Research, School Executive Committee, School Advisory Committee, School Research Committee, Postgraduate Committee, Search Committee, Building & Space Committee – all of the School of Chemistry, UNSW.
Faculty of Science Research Committee.
Instrument Advisory Team for Emu, ANSTO.
Invited lectures, conference & media presentations Solvothermal reactions for novel chemical syntheses: From graphene to MOFs, ISHA 2013, The University of Texas, Austin, USA, January 2013.
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Associate Professor Pall Thordarson B.Sc. (Iceland), Ph.D. USyd, CChem, MRACI
A/Prof. Pall Thordarson obtained his BSc. in Chemistry from the University of Iceland in 1996 and a PhD in Organic Chemistry from The University of Sydney, Australia in 2001. After a Marie Curie Post-doc in the Netherlands he returned to the University of Sydney as a research fellow in 2003. He was appointed at UNSW in 2007 and he is now an ARC Future Fellow and Associate Professor in the School of Chemistry at UNSW He received the Australian NSW Young Tall Poppy Science Award in 2008, the International SPP/JPP Young Investigator Award for 2010 and the 2012 Le Fèvre Memorial Prize from the Australian Academy of Science for outstanding basic research in Chemistry by a Scientist under the age of 40.
Current Research Activities Light-activation in bioelectronics. Self-assembled gels for biomedical applications and electroactive displays.
Biophysical chemistry and the supramolecular chemistry of proteins.
Non-linear interactions in supramolecular chemistry
Selected Publications David Hvasanov, Joshua R. Peterson and Pall Thordarson, Self-assembled light-driven photosynthetic-respiratory electron transport chain hybrid proton pump. Chemical Science, 2013, 4, 3833-3838 (back cover article).
David Hvasanov, Alexander F. Mason, Daniel C. Goldstein, Mohan Bhadbhade and Pall Thordarson, Optimising the synthesis, polymer membrane encapsulation and photoreduction performance of Ru(II)- and Ir(III)-bis(terpyridine) cytochrome c bioconjugates. Organic & Biomolecular Chemistry, 2013, 11, 4602-4612 (inside cover article).
Pall Thordarson, Determining Association Constants from Titration Experiments in Supramolecular Chemistry, Chemical Society Reviews, 2011, 40, 1305-1323.
David Hvasanov, Jörg Wiedenmann, Filip Braet and Pall Thordarson, Induced Polymersome Formation from a Diblock PS-b-PAA Polymer via Encapsulation of Positively Charged Proteins and Peptides, Chemical Communications, 2011, 47, 6314-6316.
Katie W. K. Tong, Sabrina Dehn, James E. A. Webb, Kio Nakamura, Filip Braet and Pall Thordarson, Pyromellitamide Gelators: Exponential Rate of Aggregation, Hierarchical Assembly and their Viscoelastic Response to Anions, Langmuir, 2009, 25, 8586-8592.
Professional Activities Editorial board member – Commissioning Editor, the Australian Journal of Chemistry.
Chair, Scientific Advisory Board Member, Biomedical Imaging Facility, Mark Wainwright Analytical Centre, UNSW.
Business Leader, School of Chemistry, Hazardous Materials and Dangerous Goods (HMDG) project, UNSW.
Member, Safety Committee, the School of Chemistry, UNSW.
Membership of the Royal Australian Chemical Institute, The American Chemical Society, The Royal Society of New South Wales, The Icelandic Chemical Society, Society of Porphyrins and Phthalocyanines (SPP), The Australian Microscopy and Microanalysis Society and the Marie Curie Fellowship Association.
Invited Lectures, Conference and Media Presentations “The formation of a light driven proton pump in a polymersome”, 6th International Conference on Advanced Materials and Nanotechnology (AMN-6), The University of Auckland, Auckland, New Zealand, 11-15th Feb 2013, Invited Lecture
“Self-assembled Gels: From Understanding their Formation to Applications in Drug Delivery”, 5th International Nanomedicine Conference 2013, Sydney, 1-3th July 2012, Invited Lecture.
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“A functional nanoreactor based on a Ru(II)bisterpyridine-cytochrome c bioconjugate blight driven proton pump”, Royal Australian Chemical Institute (RACI) Biomolecular Conference , Leura, NSW, Australia, 14-17th July 2013, Invited Lecture.
“A Light Driven Nanoreactor”, The 24th Southern Highlands Heterocyclic Chemistry Conference, Bowral, NSW, Australia, 25-27th August 2013, Poster Presentation.
“Determination of equilibrium constants in complex equilibria”, Third International Conference on Cucurbiturils (ICCB-3), UNSW Canberra, ACT, Australia, 18-20 November, 2013, Invited Lecture.
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Dr Chuan Zhao B.Sc. Ph.D NWU
Dr Zhao received his PhD in 2002 with an excellence award from Northwest University. He then completed 4 years of postdoctoral research at the University of Oldenburg, Germany. In 2006, he moved to Monash University as a senior research fellow. He joined UNSW in Oct 2010, and is currently a Senior Lecturer. He also holds an ARC Australian Research Fellowship.
Current Research Activities Ionic liquid electrochemistry and applications for energy.
Electrocatalysts for clean energy. Scanning electrochemical microscopy
Sensors and bionics. Selected Publications Chuan Zhao, Alan M. Bond, Xunyu Lu, Determination of water in room temperature ionic liquids by cathodic stripping voltammetry at a gold electrode, Anal. Chem. 2012, 84 (6), 2784–2791
Chuan Zhao, Douglas R. MacFarlane and Alan M. Bond, Modified thermodynamics in ionic liquids for controlled electrocrystallization of nanocubes, nanowires and crystalline thin films of silvertetacyanoquinodimethane. J. Am. Chem. Soc. 2009, 131, 16195–16205
Chuan Zhao, Alan M. Bond, Photoinduced oxidation of water to oxygen in ionic liquids BMIMBF4 as a counter reaction for fabrication of exceptionally long semiconducting polymeric AgTCNQ nanowires. J. Am. Chem. Soc. 2009, 131, 4279-4287
C. Zhao, I. Witte and G. Wittstock, Switching on cell adhesion with microelectrodes. Angew. Chem. Int. Ed., 2006, 45, 5469-5471..
C. Zhao and G. Wittstock, An SECM detection scheme with improved sensitivity and lateral resolution: detection of galactosidase activity with signal amplification by glucose dehydrogenase. Angew. Chem. Int. Ed., 2004, 43, 4170-4172.
Professional Activities Chairman of 4th Asia-Pacific Conference on Ionic Liquids and Green Processes and 6th Australasian Symposium on Ionic Liquids (APCIL-4/ASIL-6)
Secretary of Electrochemistry Division RACI
Organizing committee member for 18th Australian Electrochemistry Conference (18AEC)
Member Chartered Chemist of Royal Australian Chemistry Institute (RACI).
Member of American Chemical Society (ACS).
Member of International Electrochemistry Society
Invited Lectures, Conference and Media Presentations “Electrochemical sensing using ionic liquids: unusual properties and implications”, Dasan Conference on Bio-and Ecosensing Technology, Jeju, Korea, Nov 2013 Keynote
“Electrochemical aspects of water in ionic liquids”, 14th International Symposium on Electroanalytical Chemistry, Changchun, China, Aug. 2013
Tuning the electrolyte for enhanced water splitting. Sixth International Conference on Advanced Materials and Nanotechnology (AMN-6), Auckland, New Zealand, 11- 15 Feb. 2013
“Robust and Versatile “Wallless” Microreactors Achieved by Microcontact Printing of Ionic Liquids”, 19th Australian/ New Zealand Electrochemistry Symposium, Melbourne, Nov 2013
Awards: Australian Research Fellow, Australian Research Council
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research sectionthree head of school report academic staff research teaching and learning students school school visiting committee retirements obituaries
RESEARCH sectionthree
Associate Professor John Stride
Overview 2013
icinal Chem ed M
ry ist Organic Synthesis Chemical Biology Heterocycles Drug Design Natural Products
Core Activities
Cat al Carbon Capture Catalysed Organic Transformations Electrocatalysis Hydrogen Generation and Storage Multimetallic Assemblies
y
Scientia Professor Justin Gooding was awarded a NSW Science and Engineering Award for Emerging Research for his work into bio-sensors, and also made it onto the Analytical Scientist Annual Power List of most significant analytical chemists.
Nanomedicine Biosensors Supramolecular Chemistry Surface Chemistry Self-assembly
nd Ene is a rg ys
It is therefore perhaps no surprise that the research of several of our staff and students were recognised with a number of national and international awards and accolades;
cular Devic ole
es
2013 saw the School of Chemistry at UNSW continue to make significant advances in research related matters; increased funding revenue, more researchers and a sustained high number of research publications reflect well upon the School, promising an even brighter future.
M
Director of Research
Analytical Chemistry NMR & EPR X-ray Diffraction Neutron and Synchrotron Science Combinatorial Methods
Dr. Neeraj Sharma was awarded a NSW Tall Poppy Award in recognition of his research into battery devices and work into public discourse of science.
in Melbourne and Raju Cheerlavancha won the best poster prize at the RACI NSW Natural Products Meeting – well done to everyone.
Associate Professor John Stride picked up a UNSW Vice-Chancellor’s Award for Postgraduate Supervision.
Those ever important research metrics continued to make gains in 2013. Dr. Luke Hunter and Professors Naresh Kumar and David Black all received ARC Discovery Project awards, with UNSW Goldstar awards for ARC and NHMRC near misses going to Dr. Graham Ball, Professors Naresh Kumar & David Black and Dr. Alex Donald. Associate Professor Jonathan Morris was awarded a Faculty of Science Silverstar for the near-near miss. Research publications again hovered around 150 in 2013, an increase of 50% in the rate of publications per year over a period of only 4 years.
And finally but by no means least, our Building Manager, Dr. Toby Jackson was awarded a UNSW Faculty of Science Award for Safety, in recognition of his excellent work in maintaining the physical infrastructure of the School and ensuring a safe work place for all of us. Not to be outdone, one of our postdocs, Dr. Stuart Lowe won the Mark Wainwright Analytical Centre Early Career Researcher Oral Presentation prize at the 4th International Conference on NanoMedicine here in Sydney. Our research students also shone in 2013, with several of them picking up notable awards; Dr. David Hvasanov was awarded the 2013 Cornforth Medal for the best PhD thesis in Chemistry submitted to an Australian university in the previous year – making it the third such award to a student of the School in the last 6 years! Hamish Toop picked up the best student oral presentation at the RACI Biomolecular Division National Conference held in Leura in July 2013, whilst Robert Healey won a best poster prize at the 2013 European Cyclodextrin Conference held in Turkey, Lachlan Carter won a poster prize at the 19th Australia and new Zealand Electrochemistry Symposium
2013 was my fourth year as Research Director and at the end of the 2013, the time will come for me to pass over the reins to Associate Professor Pall Thordarson; it has been a great pleasure to serve the School as Research Director and to be a part of the remarkable achievements of the School. It is reassuring to see the School in a stronger position now than at any time that I have been at UNSW and I am sure that Palli will provide very safe hands to further strengthen the standing of the School. Without more ado, I’ll sign off here – but not without a big thank you to all of the students and staff - academic, technical and administrative - who make the School what it is.
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Research Highlights
Dr William Alexander Donald Fundamental and Applied Mass Spectrometry, Analytical Chemistry, Biophysical Chemistry Our lab is developing and applying instrumental and computational methodologies in mass spectrometry, electrospray ionization, ambient ionization, tandem mass spectrometry, and chemical separations to problems in chemistry and biology. Our current research objectives are focused on: (i) significantly improving the identification and characterization of proteins by mass spectrometry with ultrahigh sensitivity and selectivity; (ii) significantly improving the rapid and direct analysis of highly complex mixtures, such as the contents of cells, by the use of novel ionization probes and mass spectrometry without sample preparation and/or chromatography; and (iii) understanding the fundamentals of metal mediated transformations of strong organic bonds (e.g., O2 and C-H bond activation) of relevance to biological and chemical catalysis by use of gaseous ion-molecule reactions, theory, and ion spectroscopy. We use a range of state-of-the-art mass spectrometers and other instrumentation in our experiments.
Whole-protein mass spectrometry A major scientific goal is to develop the capacity to comprehensively identify and quantitate all proteins in complex mixtures, such as the contents of cells, to rapidly facilitate biological and therapeutic discoveries (i.e., proteomics). Because of the complexity, wide dynamic range, and impressive molecular diversity of biological systems, this is an immense challenge. To fully sequence an unknown protein, most current methods require the protein to be completely isolated from its biological matrix in high yield, which is time-consuming and can take weeks to months. We are working on developing and improving methods in mass spectrometry to characterize and sequence proteins faster using less sample.
Supercharging proteins in electrospray ionization for significantly improving tandem mass spectrometry measurements. We’ve developed methods to pack significantly more charge onto proteins than any other known method. This makes these protein ions significantly more amenable to sequencing and detection by many different types of tandem mass spectrometry measurements. Image is from Anal. Chem. 2014, 86, 4455-62.
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A significant barrier to improving our ability to sequence proteins by mass spectrometry is that protein ions, [Protein+zH]z+, are normally formed in relatively low charge states (low z values), which do not readily fragment unlike those in higher charge states (high z values). This is a problem because the masses of the fragments are used to determine the sequence of the protein’s amino acids (i.e., the order and identity of the protein’s amino acids that are encoded by the protein’s gene). Moreover, the sensitivity and limit of detection of many ion detectors and mass analysers significantly improve with increasing charge. Recently, we more than doubled the number of additional positive charges that can be packed onto a given protein ion by use of a new class of UNSW “supercharging” reagents (i.e., small molecules that are added to electrospray ionization solutions to form protein ions in the highest known charge states). This is significant because it enables an 8,600 Da protein to be sequenced in an experiment that takes <2 min and consumes <10-12 grams of the protein. This was also surprising because by use of these additives, we significantly surpassed the theoretical limit that was thought to prevent the addition of more charge to protein ions. We are now (i) determining the factors that limits the formation of protein ions in such high charge states so that performance can be improved further and (ii) extending our protein sequencing approach to significantly higher molecular masses that are more commonly found in biological systems (i.e., beyond 50 kDa).
Novel ionization methods Imagine a breathalyser test that can detect cancer and other diseases. The ultimate goal would be a personalised and highly accurate warning system for diagnosing disease in the earliest possible stages to maximise the possibility of recovery. This will require (i) high sensitivity, (ii) reliable detection, (iii) selective detection, and (iv) the rapid and nearly simultaneous detection of many different analytes that are indicative of disease. We are developing a compact ionisation method that can be used to directly ionise analytes from highly complex chemical mixtures by use of custom fabricated ion emitters for rapid chemical detection by mass spectrometry without sample preparation. This is important because it can be used to eliminate chromatographic equipment (e.g., compressed gases, liquid pumps, etc.), which will significantly improve the performance mass spectrometers by (i) reducing size and power requirements, (ii) increasing sensitivity and tolerance for complex mixtures, and (iii) decreasing analysis time. We ultimately aim to incorporate this ionization method into portable, hand-held mass spectrometers to enable complex chemical mixtures to be more readily analysed for personal use in the field, home, office, etc.
Portable mass spectrometer for personal chemical analysis. Improved field-deployable and compact ionisation methods are urgently required to enable complex mixtures to be directly analysed (e.g., for early detection of cancer and other diseases). Image is from J. Am. Soc. Mass Spectrom. 2008, 19, 1442-48.
Capturing and characterizing fleeting intermediates of catalytic reaction cycles For many chemical reactions, there are limited options for directly identifying and characterising short-lived intermediates in catalytic cycles because these reactive species are (i) formed in mixtures, (ii) low in abundance, and (iii) rapidly degrade owing to reactions with solvent, counter ions, and/or solvent impurities. With only limited options for directly characterising/identifying intermediates, rationally improving catalytic reactions can be highly challenging. We are developing novel approaches that combine rapid mixing technology, “ultra-soft” electrospray ionisation, and mass spectrometry to capture reactive intermediates by transferring them intact from solution into the gas phase where they can be isolated from all other species, solvent, counter ions, and solvent impurities. Once they are safely in the gas phase, reactive intermediates can be identified and carefully characterised in a highly-controlled, inert environment using several methodologies (ion spectroscopy, ionmolecule reactions, accurate mass measurements, as well as theory). We are currently demonstrating these methods by examining iron-oxo catalysts that are capable of selectively functionalising inert C-H bonds under mild conditions in useful yields. This strategy should prove useful for directly characterising the elusive intermediates of many different catalytic reaction cycles.
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Dr Jon Beves
Nanoscience Cluster Our research focuses on controlling ‘weak’ intermolecular interactions – the field of supramolecular chemistry – to form functional molecular devices, machines and materials. Metal complexes are of primary interest acting as both templates for the construction of nanoscale molecular assembles and as functional molecules featuring rich redox, photophysical and catalytic properties. Bridging disciplines from organic synthesis and coordination chemistry to solid state characterization, photophysical studies and spectroscopy, our projects are inherently multidisciplinary.
Supramolecular chemistry Supramolecular chemistry is all about the chemistry between molecules. Intermolecular interactions are generally weak such as hydrogen bonding, aromatic stacking, hydrophobic interactions and metal ionligand coordination – but it is just these types of interactions which Nature uses to control all of biology. Inspired by Nature’s talents, we are interested in the design and use of ‘weak’ interactions to form synthetic functional assemblies of molecules which can act as nanoscale machines or other useful functional molecular devices.
Coordination chemistry Coordination chemistry involves the bonding of metal ions with (normally organic) ligands to form metal ‘complexes’. These molecules have fascinating properties ranging from bright and beautiful colours to acting as efficient and robust catalysts. We study the fundamental properties of transition metal complexes and build their functionality into nanoscale structures where their rich chemistry can be combined with controlled mechanical motion or other switchable functions. One current goal is the development of luminescent molecular ‘cages’, which can act as molecular photoreactors to catalyse selective reactions within their cavities.
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Switchable molecular systems Most synthetic molecular devices operate as static (where no changes to structure or function are possible) or dynamic molecules (where the distribution of ‘states’ is determined only by their relative thermodynamic energies). However, relatively few operate in non-equilibrium conditions, which is how all of Nature drives systems energically uphill in order to perform work. We aim to use switchable synthetic systems, such as photoswitchable organic molecules, to drive systems into non-equilibrium conditions which can be coupled with the precise control of molecular processes.
Metal ions as ‘templates’: The topologies of molecules and materials, that is the relative way they are entangled or interwoven, can have a huge impact on their properties and functions. We aim to use metal ions to template the formation of highly specific molecular topologies, with an eye to controlling functional properties. Many metal ions adopt highly regular coordination geometries, such as tetrahedral, square planar or octahedral. This ‘geometric information’ can be exploited to arrange ligands in space in a very well-defined manner to template the formation of the some of the largest and most structurally complicated molecular architectures known, with applications from energy storage to molecular sensing.
Selected publications 1. J. E. Beves, V. Blanco, B. A. Blight, R. Carrillo, D. M. D’Souza; D. Howgego, D. A. Leigh, A. M. Z. Slawin, M. Symes, J. Am. Chem. Soc., 2014, 136, 2094–2100. 2. J. Yang, J. K. Clegg, Q. Jiang, X. Lui, H. Yan, W. Zhong, J. E. Beves, Dalton Trans. 2013, 42, 15625-15636. 3. J. E. Beves, C. J. Campbell, D. A. Leigh, R. Robin G. Pritchard, Angew. Chem. Int. Ed., 2013, 52, 6464-6467. 4. J.-F. Ayme, J. E. Beves, D. A. Leigh, R. T. McBurney, D. Schultz, J. Am. Chem. Soc., 2012, 134, 9488-9497 5. J.-F. Ayme, J. E. Beves, D. A. Leigh, R. T. McBurney, D. Schultz, Nature Chem., 2012, 4, 15. 6. J. E. Beves, B. A. Blight, D. A. Leigh, R. T. McBurney, Angew. Chem. Int. Ed., 2011, 50, 9260-9327.
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School Postgraduate Seminars 2013
The Postgraduate Seminar Programme continued to thrive and remained an integral part of the School monitoring and mentoring system. The School has enjoyed seminar presentations from postgraduate research students finishing the induction phase, mid-candidature and completing stages of their programme. They are held Tuesday lunchtimes and are well attended by all members of the School. The range
of topics covered in the seminars was impressive and of a very high standard. A panel of academic staff assessed each presentation and individual feedback was given to each student.
April Bradley Butler
The effect of ionic liquids on reactions at phosphorus centres
Ran Xu
Photochemistry of Organic Reactive Intermediates Monitored with NMR Spectroscopy
Murat Bingul
Synthesis of novel heterocyclic compounds that enhance the anti-cancer effects of SAHA
Ethan Howe
Bio-Inspired Supramolecular Host-Guest Architecture: Cooperativity and Allostery
Moinul Choudhury
Development of Light-Addressable Electrode Arrays
Xin Chen
Stimuli-Responsive Functionalized Mesoporous Silica Nanoparticles for Drug Release in Response to Multiple Biological Stimuli
Aravind Ramachandran
Modified electrodes to probe extracellular electron transfers in bacteria
Worawan Tantisantisom
Synthesis of Sanguinamide B derivatives: Structure-Activity Relationship and mechanism of action
Marcin Mielczarek
Design, synthesis and antibacterial activity of novel indole compounds that inhibit RNA polymerase-transcription initiation factor interaction
Amirul Islam
Novel Antibacterial Agents: Screening, Synthesis and Mechanism of Action
Alex Weremfo
Effectiveness of Electrochemically Roughened Platinum Microelectrodes for Neural Stimulation
Christopher Gardner
Synthesis and Characterization of Retinoid Enhancers for Anti-Cancer Therapies
Yao Wang
Hsp90/Hsp70 dual inhibition study in cancer treatment and discovery of novel Hsp70 inhibitors
Maryam Parviz
Dual sensing of cells attachment and spreading using electrochemical impedance and optical fluorescence microscopy
Yong Lu
Developing nanofabricated surfaces for cell biology and cell based biosensors
Ying Yang
Light Controlled Electrochemistry on Silicon Electrodes: Application to the Capture and Release of Single Cells
Cheng Jiang
Protein resistant electrodes for biosensing
Safura Taufik
Development of an Electrochemical Biosensor based on Gold Nanoparticles for the Detection of Biomarkers
May
RESEARCH / 45
June Jeanette McConnell
Synthesis and mechanistic evaluation of hsp90 inhibitors as anticancer agents
Mengchen Ge
Ionic Liquids-Based Gas Sensor
Andrew Robinson
Therapeutic peptides and peptide hydrogels for medical application
Genevieve Duche
Protein sweeteners as adjuvants in dental epoxy resin
Chao Shen
Metal-directed supramolecular cage
Ying Zhu
Micropatterned Porous Silicon Photonic Crystal Towards Single Cell Activity Monitoring
Michelle Dunn
Measuring the acidity of heterocyclic carbon acids: correlations with organocatalytic activity of the corresponding carbenes
Seong Kim
Exploring bioactive Macrocycles as anticancer drug leads
Roya Tavallaie
Detection of serum circulating MicroRNAs as cancer markers
Hendra Wahyudi
Development of Macrocyclic Peptides into Lead structures
Rain Lu
Highly efficient Co based composite catalysts for electrochemical oxygen evolution
Mark Gatus
Homo and Heterobimetallic Complexes for Tandem One-Pot Reactions
Ekaterina Nam
Surface-bound Light-activated Redox Enzyme Cascades
Stephen Parker
Towards Single-Cell Isolation Using Electrochemically-Switchable Surfaces
Abbas Barfidokht
Electrochemical Biosensor for Glycosylated Hemoglobin (HbA1c)
Lachlan Carter
Nanoparticle-mediated electrochemical gating: application to electroanalysis
Kyloon Chuah
Towards single molecule detection using nanoparticle-based nanopore biosensor
Veronica Tecchio
The Development of Pyrrolopyrimidines as Kinase Inhibitors
Nripendra Biswas
Novel small molecules for the modulation of bacterial signalling pathways
Raju Cheerlavancha
Synthesis of α,β,γ-trifluoro-δ-amino acids
Sandra Choy
Understanding Cooperative Catalysis with Bimetallic Rhodium(I) complexes
Xun Lu
Super-resolution Fluorescence Microscopy for Surface Characterization
Mokarrom Hossain
Biomass processing in ionic liquids
Iqbal Ahmed
Ring Expansion as a General Method for Improving Peptide Cyclisation
Asim Khan
Oxygen reduction in ionic liquids for fuel cells and Li-air batteries
Diep Nguyen
Design, synthesis and biological evaluation of novel isoflavonoid derivatives
Daniel Twycross
Group 10 Metal complexes: Cross coupling catalysts and heavier carbene analogues
Sinead Keaveney
Understanding and predicting organic reaction outcomes in ionic liquids
Devi Liana
Fully Integrated Paper-based Sensor
Bryan Suryanto
Metal-free Nanocarbon Electrocatalysts for Oxidation of Alcohols
Alex Mason
Developing tools for Synthetic Cell Research
Yen Chin Koay
Synthesis of macrocyclic compounds as anticancer therapeutics
Robert Healey
Supramolecular Chemistry of Natural Sweeteners
Kam Kenneth Hong
Synthesis of Novel Biologically Active Scaffolds Based on Flavonoids and Isoflavonoids
July
August
September
October
46 / annual report
November Renecia Lowe
Optimisation of molecules with biomedical potential using selective fluorination chemistry
Chin Min Wong
Hybrid Rh and Ir Catalysts Supported on Carbon Scaffolds
Christian Gunawan
Scanning Electrochemical Microscopy of Switchable Redox Enzyme Cascades
Toby Mills
Analysis of micro-organism derived compounds for drug discovery
Parisa Sowti Khiabani
Using photocatalysts in wearable sensors for sun exposure
Ashwin Nair
Transition Metal Catalysts containing N-Heterocyclic Carbene Pincer Ligands
Alistair Laos
Understanding Quantum Phenomena in Photosynthesis: Moving Toward Synthetic Mimics
Chang Long Xiao
Highly Efficient Mesoporous Multimetallic Catalysts For Electrochemical Oxygen Evolution
Kai Buys
Stabilisation of heavy group 14 metallohydrides
Hao Jiang
Synthesis of Macrocyclic Systmes linking indoles with related Heterocycles
Md Musfizur Hassan
Controlled Drug delivery from Self-assembly Gel
Yuvixza Lizarme Salas
Towards a treatment for stroke: Synthesis of analogues of dictyoquinazol A
Swahnnya De Almeida
Development of a Circulating MiRNA Biosensor for the Detection and Monitoring of Lung Cancer
December
The Harper Research Group
RESEARCH / 47
School Seminars 2013 – Invited Speakers
January Dr Stuart Thickett
UNSW CAMD
Polymer Thin Films, Nanoparticles and Self-Assembled Templates for Designer Applications
Prof. Norbert De Kimpe
Ghent University, Belgium
Syntheses of carbocyclic and heterocyclic beta-amino acid derivatives
Prof. Mauro Riccò
Università di Parma, Italy
Muons probe hydrogen interaction with carbon nanostructures
Dr Luke O Dell
Deakin University
Investigating Structure and Dynamics in Materials Using NMR: New Methods and Applications at Deakin University
Prof. Richard Andersen
University of California, Berkely
Hydrogenation of Pyridine to Piperidine by a Metallocene Lanthanide Hydride: A Mechanism and a Surprise
February
March
The Hydrolytic Kinetic Resolution Reaction Prof. Eric Jacobsen
Harvard University 2013 Andrews Lecturer
Chiral H-Bond Donor Catalysts Part 1: Probing NonCovalent Interactions Chiral H-Bond Donor Catalysts Part 2: Anion-Binding Catalysis
A/Prof. Suzanne Blum
University of California, Irvine
Microscopy for Synthetic Chemists and Dual-Metal Catalysis with Gold
Prof. Stuart Macgregor
Heriot-Watt University
Adventures in C–H and C–F Bond Activation and Functionalisation
Prof. Sebastien Perrier
Sydney University
Using Molecular Engineering to build Nanostructured Materials
Dr. Andrew Lawrence
Australian National University
Biomimetic Total Synthesis of Natural Products
Prof. Richard Keene
James Cook University / UNSW (ADFA)
Polypyridyl ruthenium(II) complexes as cytotoxic lipophilic cations: new paradigms for old molecules?
A/Prof. Michael Oelgemöller
James Cook University
From the Solar Production of Chemicals to Microflow photochemical Synthesis
A/Prof. Craig Williams
University of Queensland
Natural Product Total Synthesis And What We Learned In-between
Dr. Anthony O’Mullane
RMIT
The use of electrochemical approaches for the fabrication and characterisation of nanomaterials
Dr. Jamie Simpson
Monash University
The big and the small of it: lipid prodrugs and fragmentbased lead design
Prof. Jonathan Baell
Monash University
From antiparasitic to anticancer agents with screening, design or the literature as starting points
Dr. Jonathan George
The University of Adelaide
Biomimetic Natural Product Synthesis
April
May
June
48 / annual report
July Prof. Stefan Bräse
Karlsruhe Institute for Technology (KIT) Germany
Small molecular entities for chemical biology
Prof. Stephen Hashmi
University of Heidelberg
Highly Active Gold Catalysts
Prof. Addy Pross
Sydney University & Ben-Guiron University
How Chemistry becomes Biology? Uncovering the Chemical Roots of Darwinism
Prof. David O Hagan
The University of St Andrews, Scotland
Fluorine in rings and things
Prof. Mercedes Alvarez
Institute for Research in Biomedicine (IRB) in Barcelona
Lamellarins, from the sea to drug delivery
Prof. Ted Molinski
University of California, Davis
Heterocycles from the ‘Wine Dark Sea’ - Adventures Among Marine Natural Products
Dr Matthew J Cook
Queen’s University, Northern Ireland
New Allylic Rearrangements: From the Sigmatropic to the π-Allylic
Prof. Dirk Trauner
Ludwig-Maximilians-Universität München, Germany
The Chemistry and Photopharmacology of Red Colorants
Dr. Elizabeth New
Sydney University
Chemical approaches to studying oxidative stress and metal ions in biology
Dr. Tash Polyzos
CSIRO
Multistep Transformations in Flow Chemistry: Towards the Rapid Assembly of Complex Targets
Dr. Su Chen
Nanjing University of Technology, China
How to make materials smart
Prof. Pak-Hing Leung
Nanyang Technological University, Singapore
Palladacycle Catalyzed Asymmetric P-H Addition Reactions
Dr. Joanne Blanchfield
University of Queensland
Carbohydrate globules: hexaphenylbenzene-cored ‘snowflake’ dendrimers for presentation of Poly-Nacetylglucosamine (PNAG) polysaccharides
Dr. Sam Banister
Sydney University
Polycyclic Cage Molecules: From Drug Design to “Designer Drugs”
Prof. Andy Phillips
Yale University – Presenting the Howard Lecture
New Directions in Chemistry to Impact Novel Therapeutics
A/Prof. Richard J. Payne
University of Sydney
Synthesis of Therapeutic Glycopeptides and Glycoproteins via Novel Chemical Ligation Strategies
Prof. Tim Clark
Friedrich-AlexanderUniversität ErlangenNürnberg
Simulating “soft” electronics
Prof. Kurt Gothelf
Aarhus University – Presenting the Cavill Lecture
DNA-Programmed Assembly of Molecules and Materials
Dr. Rohan Davis
Griffith University
The Use of Australian Biota in Drug Discovery
Dr. Jack Clegg
University of Queensland
Self-assembly of metallo-supramolecular cages, barrels and cubes: subtle changes produce significant consequences
Dr. John Gehman
University of Melbourne
Intramolecular Hydrogen Bonds in Cardiolipin
Dr. Jonathan Burton
University of Oxford
Adventures in Natural Products Chemistry: Methodology, Synthesis, Structure Determination
Prof. Gerhard Wagner
Harvard
A structural approach to inhibit protein interactions in translation for targeting human cancer
Dr. Alex Bissember
University of Tasmania
Novel Transition Metal-Catalyzed Reactions: Development and Synthetic Applications
August
September
October
November
December
RESEARCH / 49
teachingand learning sectionfour head of school report academic staff research teaching and learning students school school visiting committee retirements obituaries
TEACHING AND LEARNING sectionfour
04 Overview 2013
The year 2013 saw a number of changes in the School with new staff members joining our throng – welcome to Drs Jon Beves, Alex Donald and Neeraj Sharma (Neeraj actually joined the School in late 2012) – and a sad farewell to our first year coordinator Dr Nick Roberts announcing his retirement from the School effective mid-year (more on Nick elsewhere in the Report). This year was in many ways one of consolidation where many of the changes to syllabi were given the opportunity to bed down and take effect. Many of the matters commented upon in 2012 were also features in 2013 – the demand for Chemistry across a range of Science degrees remained very strong. One notable feature is that the Higher Chemistry courses are proving extremely popular and students appreciate the more challenging material presented in them. Another important milestone saw the first cohort of Bachelor of Medicinal Chemistry students complete their Honours year. The Med Chem students along with the Science and the Nanotechnology Honours students saw our School hit the magic mark of 30 Honours students. After last year’s success where Associate Professor Richard Tilley from the Victoria University of Wellington (New Zealand) joined us briefly as the inaugural Howard Fellow, we were pleased to welcome Professor Dirk Trauner from the Ludwig Maximilian University of Munich, Germany. Professor Trauner is a world expert in the fields of complex organic synthesis, chemical genetics and chemical biology. The School was extremely fortunate to hear Professor Trauner deliver a well received and challenging series of undergraduate lectures on synthetic design to our semester 2 “Topics in Contemporary Chemistry” class. Finally, while he taught his final classes in semester 2 2012, Professor Brynn Hibbert formally announced his retirement early in the New Year. As Director of Teaching I would like to express my thanks to Brynn, who has made outstanding contributions to teaching in the School ever since joining our ranks in 1987; he has championed the School’s Chemical Analysis and Laboratory Management postgraduate coursework programs for several years, and he has been the School’s flag bearer for Analytical Chemistry (as its Professor). But above all he has been an enthusiastic and charismatic teacher at all levels. There is something about a jolly Englishman with a bushy beard the School will find very hard to replace. A long and happy retirement, my old chum! Dr Gavin L. Edwards Director of Teaching
52 / annual report
First Year Chemsitry
Enrolments in First Year Chemistry remained high in 2013 Session 1:
Session 2:
Session 3:
CHEM1001
82
CHEM1011
345
CHEM1011
510
CHEM1021
326
CHEM1031
531
CHEM1041
272
CHEM1051
24
CHEM1061
22
CHEM1151
25
CHEM1829
135
CHEM1831
99
CHEM1021
The administration of first year chemistry underwent some major changes in 2013. Following the retirement of the former First Year Director, Dr Nick Roberts, his academic and administrative duties were split between two new roles. Dr Luke Hunter is the new First Year Academic Coordinator, and his responsibilities include academic matters such as syllabus development, pedagogical strategies, and setting of exams. Mr Steve Yannoulatos is the new Student Support Manager, and his responsibilities include managing student enrolments, fielding dayto-day student enquiries, and supporting the online learning management system. Dr Ron Haines retains his position as First Year Laboratory Director, and Ms Anna Choy continues in her role as Head Tutor. As well as the personnel changes described above, there have been changes in teaching methods. The University has transitioned its online learning management system from Blackboard to Moodle, and this has allowed the School of Chemistry to make innovations that offer richer and more personalised feedback to students. For example, the weekly computer assignments that students previously
74
completed in the Gibson Computer Laboratory are now available in an updated format on Moodle, with personalised feedback offered for correct and incorrect responses. In another example, the Q+A forum within each course’s Moodle page is an intensively-used resource in which students seek advice from lecturers (and, more often than not, from their peers too). Another change this year has been a new automated system for collecting statistics on exam results, and feeding these results back to the teaching staff. This allows staff to recognise, for the first time in recent years, which topics are being grasped successfully by students, and which need more emphasis in lectures. This gives us another tool to continuously enhance the quality of our first year learning and teaching. Several further innovations are in the pipeline. We are gradually incorporating aspects of a “flipped classroom” model; we are assembling a central resource of lecture demonstration materials; and we are working towards a new mode of skills-based assessment in laboratory classes. Updates on these exciting developments will be communicated in a subsequent report.
TEACHING AND LEARNING / 53
Honours Program
The term ‘Honours Program’ in the School of Chemistry covers several UNSW undergraduate Programs. Our Honours cohort includes students enrolled in the (i) Bachelor of Science majoring in Chemistry, (ii) the Bachelor of Advanced Science majoring in Chemistry, (iii) the Bachelor of Science in Medicinal Chemistry, and (iv) the Bachelor of Science in Nanotechnology. Students from several other degree programs, such as the Bachelor of Environmental Science majoring in Chemistry, are also enrolled in the Bachelor of Science majoring in Chemistry program. In the first two ‘chemistry’ focused degrees, students undertake their entire fourth year in the School of Chemistry. This comprises a research project in collaboration with a member of the academic staff and contemporary chemistry courses delivered by formal lectures. In the ‘medicinal chemistry’ focused degree, students follow the above but also have a greater
2013 MedChem Honours Cohort
interaction with academic staff in the Pharmacology section of the School of Medical Sciences, including collaborative projects. The BSc Nanotechnology students undertake a research project that represents just over 80% of their final year. This is carried out in the School of Chemistry, the School of Physics and/or the School of Materials Science and Engineering, and is supplemented by a number of undergraduate courses taught by these three Schools. In 2013, seventeen (17) students completed Honours through the Bachelor of Science and Advanced Science BSc Programs, fifteen (15) completed Honours through the Bachelor of Medicinal Chemistry, with a further two beginning Honours in July 2013. Four (4) students completed their Bachelor of Science in Nanotechnology with research projects in the School of Chemistry.
54 / annual report
Postgraduate Programs and Courses
Chemical Analysis and Laboratory Management Two major changes impacted the implementation of the Chemical Analysis and Laboratory Management (CALM) program in 2013. Firstly, due to the retirement of Professor Brynn Hibbert, who for several years was the academic leader of the CALM program, new staff were required to take over teaching responsibilities. In 2013, CHEM7115 was delivered by Dr Danmar Gloria, who did an excellent job. It was decided that CHEM7111, a specialised key component of the program (formerly taught by Professor Hibbert), would not be offered in 2013 but would be re-established in 2014 when a suitable replacement is established on campus and available to teach CHEM7111. Secondly, due to a university wide review of postgraduate coursework offerings and entry level standards, a major review of the available programs was undertaken. The main outcomes of this review were as follows: The CHEMAS8708 CALM Masters program was changed so that students commencing the program from 2014 onwards will require an Honours degree or equivalent (Graduate certificate, BSc plus two years relevant experience) to enter the program. This is significantly more demanding than in previous years and may reduce the number of eligible applicants in the future. Students will need to complete either CHEM7122 Analytical Project or a new course to be introduced in 2014, CHEM7124 Real World Analytical Chemistry, in order to fullfil the capstone course requirement of coursework masters programs in the future.
CHEMAS7429 CALM Graduate Certificate program, a replacement for the existing CHEM7428 Graduate Certificate program was introduced in 2013. Students enrolling in the new 7429 program will not be allowed to transfer to the Masters Program with associated transfer of credit. They will need to graduate from the 7429 program first in order to obtain the graduate certificate to make them eligible to enter the 8708 Masters program. The CHEMAS5648 Graduate Diploma was removed as a stand alone program. Students entering the Masters program may still exit early with a graduate diploma.
TEACHING AND LEARNING / 55
Postgraduate Research
Postgraduate research (HDR) student enrolments continue to grow in 2013, with 24 new HDR students enrolled over both the sessions. In 2013, the School had 88 PhD, 8 MSc and 3 MPhil students actively enrolled. Concurrent with this healthy growth, we have seen a significant increase in completions of HDR degrees, with 16 HDR students submitting their theses in 2013. A further 15 PhDs and 2 MSc students graduated in 2013. Importantly, our first ever MPhil student completed and graduated in 2013. The quality of our students and their research was recognised with a number of externally awarded prizes, with the most significant being the award of the RACI’s Cornforth medal to Dr David Hvasanov. The Cornforth Medal is awarded to the candidate who is judged to have completed the most outstanding PhD thesis in a branch of chemistry, chemical science or chemical technology under the auspices of an Australian University. UNSW has now won this award three times in the last 5 years.
56 / annual report
Outreach Activities
The School of Chemistry outreach program was established in 2007 to foster stronger links with high schools and to stimulate an interest in science and technology in high school students.
The School has organised a variety of programs and events in the past year to meet these goals.
School visits The School of Chemistry has once again been very active in hosting visits from various high schools near and far in the past year. The schools hosted this year included Waverley College, Sydney Grammar School and Mount Sinai College, in addition to regular attendees. The School of Chemistry has put together a comprehensive set of hands-on chemistry experiments for Year 10 and Year 12 students. The students took an active part in experiments, which involved fatty acid analysis of an oil sample, preparation of biodiesel, determination of sulfate in fertilizer, and calcium in milk, and a demonstration on magic bottle, luminol reaction, elephant toothpaste and atomic absorption and infrared spectroscopy. The students thoroughly enjoyed the visit and the feedback from the high schools has been extremely positive. In particular the students enjoyed working in real Chemistry laboratories and undertaking advanced experiments that exposed them to new equipment and modern chemical techniques.
Presentation at the Science Teachers’ Association of NSW (STANSW) Chemistry Conference The School has continued to maintain strong links with the Science Teachers’ Association of NSW (STANSW) giving a presentation on the HSC topic “Atmospheric Chemistry – Ozone and CFCs” at the STANSW Chemistry Teachers Conference on 06 May 2013. The presentation included background theory, teaching ideas such as analogies, demonstrations and experiments and links to some relevant web resources. The teachers really appreciated the opportunity to
gain a deeper understanding of the topic areas and links to new resources. The feedback from the teachers from the event was extremely positive with quotes like “Can you please email me the electronic copy of the wonderful presentation you did for the chemistry conference on ozone” Alpana Kumar, Head Teacher Science, Thomas Reddall High School.
Participation in the outreach programs organised by the Faculty of Science Science Parent/Student night The School actively participated in this highly successful event organised by the Faculty and answered a number of queries from year 11 and year 12 students keen to do science at the university level.
Nura Gili Winter Schools Program A number of indigenous high school students took part in the Science stream of this program, taking a tour of the chemistry building and undertaking some chemistry experiments. The students thoroughly enjoyed the day and found it highly educating.
Science High School Information Day The objectives of the UNSW Science Info Day is to entice potential students to UNSW by showcasing the range of different Science experiences available through lectures and hands-on activities in laboratories. The School oranised hand-on chemistry activities for the visiting students and presented a short talk on options for studying chemistry at UNSW.
UNSW Open Day 2013 The School actively participated in the UNSW Open Day 2013, with academics stationed at the Scientia Advisory Centre to answer questions regarding the chemistry programs. Two
TEACHING AND LEARNING / 57
Asia Pacific Institute of Nuclear Science (APINS) Short Courses The APINS short course continued successfully in July and November this year. The â&#x20AC;&#x2DC;Radiation Safety for X-Ray Equipment Personnelâ&#x20AC;&#x2122; course aims to equip participants who are seeking a license for the installation and servicing of X-ray equipment with the knowledge necessary to recognise potential hazards and to minimise exposure to external ionising radiation. This course is an accredited training course across Australia. The course presenters in 2013 were, Mr. Colin Hockings, Mr. Paul Cardew and Mr. Robert Armstrong.
58 / annual report
Students from Waverley College during an Outreach visit.
presentations on “Chemistry – A Diverse and Expanding Science” were delivered, and seminars on “Medicinal Chemistry” and “Nanotechnology” attracted significant interest. Academics and an army of postgraduate students ambushed passing high school students at the chemistry marquee, which hosted a variety of new and old favourite demonstrations which had our visitors captivated. Overall the event was a resounding success and there was a lot of interest in Chemistry, Medicinal Chemistry and Nanotechnology.
Medicinal Chemistry and Nanotechnology Information Evening The School of Chemistry hosted an information evening featuring Medicinal Chemistry and Nanotechnology. Year 10, 11 and 12 students and their parents were invited to learn about career opportunities in chemistry and had a chance to speak with current students and academic staff.
Hosting work experience students This year the School of Chemistry hosted 5 work experience students who worked under the supervision of postgraduate mentors, experiencing first-hand the joys and thrills of research. The feedback from the students was really positive. Many thanks for being so warm and friendly to Rhys during his work experience....he came home everyday very excited and happy!! He loves the buzz of uni life and more importantly found all the varieties of studies fascinating. Regards Linda Cumines
TEACHING AND LEARNING / 59
Degrees Awarded 2013 Graduate Dr. Marina Timerbulatova with her supervisor Professor Barbara Messerle Graduate Dr. Dominic Francis (left) with Dr Jason Harper
Master of Science and Technology Master of Science by Research Degrees in Chemical Analysis and Awarded in 2013 (Program MSc2910 & MPhil 2475) Laboratory Management (MSc Tech, Program 8708) Eiman Mohmmadali Alahmadi
Brent Harrison
Rasha Ali Alasmari
Chih Hsien Hsiao
Mashael Tayih Alharbi
Huiping Huang
Turki Hamid Alhiji
Zhouyue Lv
Hajar Hmoud Alhwaiti
Amin Matin
Eman Abdullah Aljohani
Susan Nguyen
Mohammad Amin Habl Almatin
Tian Luo.
Jameel Ali Alqahtani
Mancen Zhao
Candidate
Research Area
Supervisor
William Rouesnel 2910
Silver nanocubes for surface nanostructure assembly
Scientia Prof. Justin Gooding
Worawan Tantisantisom 2910
Synthesis of Sanguinamide B derivatives and their mechanism of action
A/Prof. Shelli McAlpine
Joana Da Rocha 2475
The development of pyrrolopyrimidine libraries
A/Prof. Jonathan Morris
Raed Dakhel Alsobhi
Doctor of Philosophy (Ph. D, Program 1870) Candidate
Research Area
Supervisor
Eleanor Jane Eiffe
The synthesis of novel, biologically active isoflavone analogues
Prof. Naresh Kumar
Dominic Vincent Francis
Towards functional fluorous surfactants
A/Prof. Roger Wayne Read
Jiabin Gao
Crystal engineering of bicyclo[3.3.0]octane derivatives
Emeritus Prof. Roger Bishop
Ryan James Gilbert-Wlson
The use of sterically bulky phosphine ligands in iron and ruthenium dinitrogen chemistry
Prof. Leslie David Field
Kitty Ka Kit Ho
The development of novel antimicrobial coatings based on dihydropyrrolones
Prof Naresh Kumar
David Hvasanov
Light-harvesting bioconjugates as chloroplast mimics
A/Prof. Pall Thordarson
Scott Anthony Jamieson
Structural evolution in self-assembled gels
A/Prof. Pall Thordarson
Wei Jiang
Metrology and comprehensive characterisation of functionalised gold nanoparticles in different media
Scientia Prof. Justin Gooding
Adeline Yolanda Lukmantara
Synthesis and structure-activity relationships studies of novel thiosemicarbazone derivatives as potential anti-cancer agents
Prof. Naresh Kumar
Giulia Mancano
Iridium and rhodium pyrazolyl and carbene based catalysts for X-C bond formation
Prof. Barbara Ann Messerle
Pauline Michaels
Development of a stable sensing interface for an electrochemical impedance label-free DNA hybridisation biosensor
Prof. Brynn Hibbert
Ellaine Joan Munton
Improved calibration and measurement uncertainty estimation for stable carbon isotope ratio measurements for the detection of steroid abuse
Scientia Prof. Justin Gooding
Thi Oanh Nguyen
Iron, rhodium and iridium catalysts with N,N- and P,N- donor ligands for amine and alcohol synthesis
Prof. Barbara Ann Messerle
Venty Suryanti
Self-assembly and anion recognition studies of N-glyoxylamides
Prof. Naresh Kumar
Marina Timerbulatova
Bimetallic complexes as catalysts for tandem reactions
Prof. Barbara Ann Messerle
60 / annual report
UNSW open day â&#x20AC;&#x201C; September 2013
TEACHING AND LEARNING / 61
62 / annual report
Postgraduate Research Completions These students have had their thesis examined and will graduate in 2014 Master of Science by Research (Program MSc 2910 & MPhil Program 2475) Candidate
Research Area
Supervisor
Yeng Ying Lee
Developing Ruthenium-Based Complexes as Redox Labels for Electrochemical Biosensors
Prof. Barbara Messerle
William Rouesnel
Silver nanocubes for surface nanostructure assembly
Scientia Prof. Justin Gooding
Doctor of Philosophy (Ph. D, Program 1870) Candidate
Research Area
Supervisor
Murat Bingul
Synthesis of novel heterocyclic compounds that enhance the anticancer effects of SAHA
Prof. David Black & Prof. Naresh Kumar
Xin Chen
Making inorganic oxides stimuli responsive via surface modification
Scientia Prof. Justin Gooding
Moinul Choudhury
Development of Light-Addressable Electrode Arrays
Scientia Prof. Justin Gooding
Samantha Furfari
The Synthesis and Applications of 4,5-Brominated N-Heterocyclic Carbenes and Kinetically Stabilised Group 13 Hydrides
A/Prof. Marcus Cole
Bakul Gupta
Porous Silicon Photonic Crystals Towards Monitoring Protease Activity In Vivo
Scientia Prof Justin Gooding
Camille Holt
Pathways to neutral and cationic alkane sigma complexes
Dr Graham Ball
Rima Raffoul Khoury
Multi-way models of multi-way interactions between copper (II) ions and tri-peptides containing glutamic acid, glycine and histidine
Scientia Prof. Justin Gooding
Alexander McSkimming
Metal Complexes with ligand-tethered organo-hydride donor groups â&#x20AC;&#x201D; new prospects for efficient multi-electron reduction
A/Prof. Stephen Colbran
Justin Nash
Developing synthetic approaches towards Embellistatin and natural product inspired libraries
A/Prof. Jonathan Morris
Andrey Tregubov
Rh complexes bearing N,N and N,P ligands immobilized on carbon support - recyclable catalysts
Prof. Barbara Messerle
Warren Truong
Interactions of Self-Assembled Gels with Living Systems
A/Prof. Pall Thordarson
TEACHING AND LEARNING / 63
Summer Scholarships
Supervisor Jeffrey Black
Faculty of Science
Dr. Leigh Aldous
Jacqueline Liu
Faculty of Science
A/Prof. Jonathan Morris
Albert Woffenden
Faculty of Science
Prof. Barbara Messerle
Sharon Yu
Faculty of Science
Dr. Jason Harper
Virginia Gigi Cheng
School of Chemistry
A/Prof. Marcus Cole
Vera Diachenko
School of Chemistry
A/Prof. Steve Colbran
Thomas Frith
School of Chemistry
A/Prof. Marcus Cole
Rebecca Hawker
School of Chemistry
Dr. Jason Harper
Tom Hawtrey
School of Chemistry
A/Prof. Jonathan Morris
Hui Qi Kweh
School of Chemistry
A/Prof. Jonathan Morris
Yun Cheuk Leung
School of Chemistry
Prof. Naresh Kumar
Matthew Mudge
School of Chemistry
A/Prof. John Stride
Catherine Onie
School of Chemistry
A/Prof. Steve Colbran
Catherine Onie
School of Chemistry
A/Prof. Steve Colbran
Wuan Xin
School of Chemistry
Dr. Leigh Aldous
Ming Zeng
School of Chemistry
Prof. Naresh Kumar
Keiran Rowell
School of Chemistry
Dr. Graham Ball
64 / annual report
Practicum Students
Home Institution
Supervisor
Jiajia Yang
Nanjing University
Dr Jonathon Beves
Lin Zhu
Nanjing University
Dr Jonathon Beves
Ahibur Rahaman
Lund University, Sweden
A/Prof. Steve Colbran
Chun Chieh Lin
San Diego State University
A/Prof. Shelli McAlpine
Charlotte Serre
Ecole Nationale Superieure des Ingenieurs en Arts Cimiques Et Technologiques, France
Dr Neeraj Sharma
Zaki Krag Nielsen
University of Copenhagen, Denmark
A/Prof Pall Thordarson
Sui Tung Clara Fong
UNSW
Dr Chuan Zhao
Yehezkiel Henson
UNSW
Dr Chuan Zhao
TEACHING AND LEARNING / 65
Programs and Activities
UNSW Chemical Society
The Cavill Lecture, 24th October 2013
The UNSW Chemical Society assists in the organisation of the School Seminar Series, a weekly program of talks from distinguished academics around Australia and the world. In addition the society organises a number of prestigious, endowed lectureships each year, and in 2013 it played host to two outstanding international researchers:
Professor Kurt Gothelf from Aarhus University, Denmark
The Andrews Lectures Professor Eric Jacobsen, Sheldon Emery Professor of Chemistry, Department of Chemistry and Chemical Biology, Harvard University, USA
19th March 2013, Rupert Myers Lecture theatre The hydrolytic Kinetic Resolution Reaction
20th March 2013, Rupert Myers Lecture Theatre Chiral H-Bond Donor Catalysts Part 1: Probing NonCovalent Interactions
21st March 2013, Rupert Myers Lecture Theatre Chiral H-Bond Donor Catalysts Part 2: Anion-Binding Catalysis
â&#x20AC;&#x153;DNA-Programmed Assembly of Molecules and Materialsâ&#x20AC;?
students sectionfive head of school report academic staff research teaching and learning students school school visiting committee retirements obituaries
Students sectionfive
05 School of Chemistry Undergraduate Student Prizes 2013
Honours Prize Winners The Angyal Prize Best performance in Honours Chemistry
The RACI Analytical Chemistry Group Prize Best performance in Level 3 Analytical Chemistry Tom Jordan Hawtrey
Vera Diachenko
The CETEC Prize Best performance in Honours Thesis Vera Diachenko and Nicholas Konstandaras
Third Year Prize Winners The Du Pont Prize Best performance in BSc 3 Year Degree in Chemistry Overall â&#x20AC;&#x153;TOPâ&#x20AC;? of Chemistry
The Inglis Hudson and Jeffery Bequests Best performance in Level 3 Organic Chemistry Tom Jordan Hawtrey
The University of New South Wales Chemical Society Dwyer Prize Best performance in Level 3 Inorganic Chemistry Max Shai Guerry
Tom Jordan Hawtrey
The Bosworth Prize
The Cowper Prize
and Medal for best performance in Level 3 Physical Chemistry
and School Medal for best performance in Level 3 Chemistry Tom Jordan Hawtrey
The Cavill Prize Best performance in Level 3 Medicinal Chemistry Tom Jordan Hawtrey
John Chien Tsai Su Alexandra Daryl Ariawan and Keiran Rowell
The University of New South Wales Chemical Society Parke-Pope Prize Meritorious performance in Level 3 Chemistry Courses Max Shai Guerry Sharon Sze Wing Yu and Alexandra Daryl Ariawan
68 / annual report
Second Year Prize Winners The School of Chemistry Prize and School Medal for best performance in Level 2 Chemistry Paige Marie Erenora Hawkins
The University of New South Wales Chemical Society George Wright Prize Meritorious performance in Level 2 Chemistry Courses Stephen Michael Butler and Ena Thea Luis
First Year Prize Winners The June Griffith Memorial Prize and School Medal for best performance in Level 1 Chemistry
Betty Huang and Tim Eddy
Postgraduate Prizes, Scholarships and Fellowships Don Craig Memorial Prize For excellence in research using X-ray crystallography Matthew Robert Gyton
Paddon-Row Scholarship For the highest ranked commencing local PhD student Vera Diachenko
Black Scholarship For the highest ranked commencing international PhD student Leila Zarei
Vincent Lok Hang Chiu
Teaching Fellowship Holders The University of New South Wales Chemical Society Prize Meritorious performance in Level 1 Chemistry Courses James Bernard Scott
Year 10 Prize Winner The School of Chemistry Prize For Excellence and Enthusiasm in Chemistry for Year 10 students Maggie Tong â&#x20AC;&#x201C; Sydney Girls High School
Undergraduate Scholarships and Awards Howard Awards Callum Savage and Surabhi Naik
UNSW Faculty of Science Summer Vacation Research Scholarships Paige Hawkins Ena Thea Luis Laura Jeffress Christina Gonzalez
UNSW Chemistry Video Competition
Jeffrey Black Mokarrom Hossain Jet Cheng Sinead Keaveney Sandra Choy Kelvin Lee Kyloon Chuah Alex Mason Andrew Danos Andrew Robinson Chris Gardner Chin Min Wong Mark Gatus
Students / 69
70 / annual report
Postgraduate Student Awards and Prizes
3rd European Conference on Cyclodextrins (Antalya, Turkey) Robert Healey (Supervisor: A/Prof. Pall Thordarson), poster prize, “Cyclodextrin Interactions with G-Protein Coupled Receptor Agonist Peptide Mimic”
Australian Institute of Nuclear Science and Engineering (AINSE) Stephen Parker (Supervisor, Scientia Professor Justin Gooding), Post Graduate Research Award (2011 – 2013)
19th Australian and New Zealand Electrochemistry Symposium Lachlan Carter (Supervisor: Scientia Professor Justin Gooding), Winner – Poster Presentation: “Utilising Nanoparticle-Mediated Electrochemical Gating to Prepare a Novel Sensing Platform”.
Robert Healey receiving the award for his poster prize.
Hamish Toop (Supervisor A/Prof. Jonathan Morris), “Total Synthesis of Dioncophylline E and Other Related Naphthylisoquinoline Alkaloids”, Poster Presentation Prize
RACI – 2013 Cornforth Medal David Hvasanov (Supervisor A/Prof Pall Thordarson) - For the best PhD Thesis on Chemical Research by a RACI member in the preceding 12 months in Australia.
School of Chemistry – Research Poster Prizes The three School Poster Prizes were awarded to:
Catalysis & Energy: Mark Wainwright Centre ECR 4th International Conference on NanoMedicine Roya Tavallaie (Supervisor: Scientia Professor Justin Gooding) Winner – Poster Presentation: “An E-DNA Based Electrochemical Biosensor for Detection of MicroRNA miR-21”.
RACI Biomolecular Division Conference ‘in the Bush’
Bradley Butler (Supervisor, Dr Jason Harper) “The effect of ionic liquids on reactions at phosphorus’
Medicinal Chemistry: Christopher Gardner (Supervisor, Prof. Naresh Kumar) ‘Identification and characterization of novel small molecules which enhance the retinoid anti-cancer signals’
Nanoscience:
Hamish Toop
Fatemeh Mir Najafi Zadeh
(Supervisor A/Prof. Jonathan Morris) Oral Presentation Prize - Examining AAL(S) as a New Lead for the Treatment of Leukaemia.
(Supervisor, A/Prof John Stride) The Investigation of Cytotoxicity of Highly Luminescent Water Soluble Quantum Dots in Colon Cancer Cells’
RACI Natural Products Symposium
47th Universities of Scotland Inorganic Chemistry Conference
Raju Cheerlavancha (Supervisor: Dr Luke Hunter) “Synthesis of α,β,γtrifluoro-δ-amino acids,” - Equal 1st prize for poster presentation.
Sandra Choy (Supervisor Professor Barbara Messerle) Winner – Poster Presentation “Flat Rh(I) complexes for catalysed hydroalkoxylation and hydroamination reactions”
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SOCS 2013 Presidents Report
The Students of Chemistry Society has had a busy year through the end of 2012 and into 2013. There have been a number of exciting SOCS events and we continue to play a role in a number of faculty events.
The executive were elected (see below) and the planning for the year ahead commenced quickly. President:
Andrew Robinson
Treasurer:
Tim Fang
Secretary:
William Hart
Social Coordinator:
Stephen Parker
Publicity Officer:
Sandra Choy
Merchandise:
Rebecca Hawker
Arc Representative:
Chris Gardner
Med. Chem. Rep:
Marwa Rahimi
Nano. Rep:
Jeffery Black
One of the first acts was to prepare a social calendar of events for 2013, which was displayed around the School to maximise participation of postgrads as well as undergrad students. SOCS helped with a number of School events at the end of 2012 by providing the muscle and man power to prepare food for both the Howard and Andrews Lecture series. Added to that, SOCS hosted a BBQ for the honours cohort of 2012 to celebrate the fact they all submitted their thesis – on time. We also contributed to the set up of School Poster Day.
Setting-up seems to be a SOCS speciality as we were there again to help with the School end-of-year celebration and arranged free sporting activities for all students and staff during the afternoon (it was a huge success and will hopefully be repeated). Our first real event in 2013 was the organisation of a stall in O-week where we lined up goodie bags, information on SOCS and the School of Chemistry, as well as demonstrating experiments daily that were a huge hit with the incoming students. We also held a guessing competition involving candy in scientific glassware, which was very popular and excited a lot of undergraduates. SOCS next organised a BBQ where we provided free snags and drinks for students of chemistry – again a huge success with record attendance for a chemistry BBQ and a lot of happy faces. The annual SOCS trivia night followed this and was, as usual, a fantastic and fun filled evening with a lot of competition amongst students for the title of chemistry trivia champions! Special thanks go to Jason Harper and Stephen George for their questions and presenting skills. Prizes were awarded for the winning (and 2nd last) teams, and I’m pretty sure there’s still a robotic remote controlled tarantula roaming the halls of the School of chemistry.
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Movie night was the next planned event. It was a bit of a flop, but at least four people got a free showing of Pirates of the Caribbean in G05. The 11th annual SOCS Chem Ball was arguably the most successful to date with a full house in attendance! The theme this year was carnival, with people dressing up in a spectacular fashion for the night. SOCS organised a three-course meal as well as a series of carnival games with the winning tables awarded prizes. The night was a great chance for academics and students of all ages to mingle and the location at Novotel Darling Harbour was stunning, complete with fireworks! We attempted to hold a SOCS poker night but low turnouts lead to a significant loss. It was still a fun night for those few who turned up! With prizes awarded for the winners (and losers). And directly after our Annual General Meeting in which this report will be read we will be holding the International Food night! This is always a fun event and will give the new executive a chance to take the reins of the society. Thanks to all of the students who played a part in SOCS over the course of 2013. Your input and enthusiasm has helped make SOCS the successful society it is today and we couldnâ&#x20AC;&#x2122;t do what we do without you! Also thanks to the School of Chemistry for its continued support, as well as Arc for both financial and general assistance with so many of our events. I wish the society and the new executive the best, and I hope they have as much fun as we had over the next year! Andrew (Robbo) Robinson SOCS President 2013
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school sectionsix head of school report academic staff research teaching and learning students school school visiting committee retirements obituaries
School sectionsix
06 Staff Administration Head of School Professor Barbara Ann Messerle, BSc PhD Syd.
Deputy Head of School Scientia Professor John Justin Gooding, BSc Melb., DPhil Oxon
Director of Research
Dr Luke Hunter, BSc( Adv)(Hons), PhD USYD (Jul è
Marcus Lawford Cole, BSc (Hons) PhD Cardiff
Laboratory Coordinator
Shelli Renee McAlpine, BSc Ill, PhD UCLA
Associate Professor Stephen Boyd Colbran, BSc PhD Otago IT Coordinator Dr Ronald Stanley Haines, BSc PhD UNSW
Seminar Coordinator
Jonathan Morris, BSc UWA, PhD ANU John Arron Stride, BSc (Hons.) PhD E.Anglia Pall Thordarson, BSc Iceland, PhD Syd
Associate Professor John Arron Stride, BSc (Hons.) PhD E.Anglia
Dr Neeraj Sharma,
Director of Teaching
Outreach Coordinator
Graham Edwin Ball, BSc PhD Sheffield, MRACI
Dr Gavin Leslie Edwards, BSc PhD Monash, CChem, MRACI
Dr Luke Hunter, BSc(Adv)(Hons), PhD USYD
Gavin Leslie Edwards, BSc PhD Monash, CChem, MRACI
Deputy Director of Teaching & Talented Students Program
Administrative Officer
Jason Brian Harper, BSc Adelaide, BSc ANU PhD ANU
Dr Jason Brian Harper, BSc Adelaide, BSc ANU PhD ANU
Post Graduate Research Coordinator Associate Professor Jonathan Morris, BSc UWA, PhD ANU
Graduate Studies Coordinator Dr Graham Edwin Ball, BSc PhD Sheffield, MRACI
Higher Year (2nd – 4th year) Coordinator
Rick Sai Kin Chan, BBus Curtin
Office Administrator
Senior Lecturers
Nicholas Kenneth Roberts, BSc PhD W.Aust., CChem, MRACI
Jodee Anning, BA UNSW
Chuan Zhao, BSc Shaanxi, MSc PhD Northwest UT
Teaching Staff
Lecturers
Professors
Leigh Aldous, BSc (Hon) Leeds, PhD Queen’s
David St Clair Black, MSc Syd., PhD Camb., AMusA, CChem, FRACI John Justin Gooding, BSc Melb., DPhil Oxon Naresh Kumar, MSc Punj., PhD W’gong., CChem, MRACI
Associate Professor Pall Thordarson, BSc Iceland, PhD Syd
Barbara Ann Messerle, BSc PhD Syd.
First Year Coordinator
Associate Professors
Dr Nicholas Kenneth Roberts, BSc PhD W.Aust., CChem, MRACI (Jan – Jul)
Stephen Boyd Colbran, BSc PhD Otago
Jonathan Beves William Alexander Donald, BSc Seattle, PhD UCA Berkley Ronald Stanley Haines, BSc PhD UNSW Luke Hunter, BSc (Adv)(Hons), PhD USYD Neeraj Sharma, BSc (Hons) PhD USYD
Associate Lecturer Anna Choy, BSc (Hons), UNSW
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Casual 1st Year Teaching Staff Dr Kakali Chowdhury, PhD, Uni New Dehli, India Joan P. Ross, BSc Syd.
Research Staff Professor Leslie D. Field (Deputy Vice Chancellor – Research)
Postdoctoral Researchers / Research Associates Manohari Abeysinghe, BSc, PhD Wales Mahiuddin Alamgir, B.Pharm (Hons), M.Pharm Jahangirnagar, PhD UNSW Simone Ciampi, BSc Modena, PhD UNSW Renxun Chen, BSc (Hons), PhD UNSW Milena Czyz, PhD UNSW Nadim Darwish, BSc Lebanese, PhD UNSW Lida Ezzedinaloo, MSc Shahid Chamran University, Iran Dominic Frances, BSc PhD, UNSW
Samantha Furfari, BSc (Hons) PhD, UNSW
Janjira Panchompoo, BSc Thailand, DPhil, Oxford, UK
Xiang-Guo Hu, PhD, Institute of Chemistry, Chinese Academy of Sciences
Joshua Peterson, BSc Wash, PhD USyd
Kitty Ho, BSc (Hons), PhD, UNSW David Hvasanov, PhD, UNSW George Iskander, BSc MSc PhD Khartoum, FRSC, MRSC, RACI Samuel Kutty, BSc (Hons), PhD, UNSW
Deborah Ramsey, BSc Alabama, PhD Wake Forest Sumi Shrestha, MSc Tribhuvan University, Nepal Alexander Soeriyadi, PhD UNSW Gordon Sutton, BSc, PhD ANU
Hsiu Lin Li, BSc (Hons), PhD Monash
Khuong Vuong, BSc, USyd, BSc (Hons 1, University Medal), PhD, UNSW
Xuechao Liu, BSc Normal, PhD Najing University
David Barney Walker, MSc & PhD Edinburgh University, UK
Stuart Lowe, PhD Imperial College, London
James E.A. Webb, PhD, USYD
Alison Magill, BSc (Hons), PhD UTas
Kasey Wood, BSc, PhD, UNSW Hon Man Yau, BSc, PhD, UNSW
Adam Martin, PhD, UWA
Fangtong Zhang, MSc UNSW, PhD USyd
Thomas Martin, MChem, PhD, Bath University, UK
Visiting Fellows
Alex McSkimming, BSc (Hons) UNSW Boon Ng, BSc, PhD, UTAS Michael Page, BSc (Hons 1), PhD, UNSW
Emeritus Scientia Professor Michael Nicholas Paddon Row, BSc Lond, PhD ANU, CChem, FRSC, FRACI
Postdoctoral research staff: Back row: Janjira Panchompoo, Michael Page, Stuart Lowe, David Barney Walker, James E.A. Webb, Adam Martin, Joshua Peterson Front row: Boon Ng, Xiang-Guo Hu, Renxun Chen, Samuel Kutty, Kitty Ho, Hsiu Lin Li, Samantha Furfari
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Emeritus Professors Roger Bishop, BSc St And., PhD Camb., CChem, FRSC, FRACI David Brynn Hibbert, BSc PhD Lond., CChem, MRSC, FRACI
Dr Ashok Nanjundan, Institute for Nanoscience and Cryogenics – Grenoble, France Prof. David O’Hagan, The University of St Andrews, UK
Conjoint Professors
Prof. Scott Rychnovsky, University of California, Irvine
Grainne Mary Moran, BSc PhD NUI, CChem, MRACI
Prof. Dirk Trauner, University of Munich
Professorial Visiting Fellows Alan Norman Buckley, BSc Syd., PhD Monash, MRACI Margaret M. Harding
Professional and Technical Staff Administrative Support Anne Ayres
Michael James, BSc Syd, PhD Cambridge, MRACI
Kenneth Gerard McGuffin, BA Syd
Ronald Postle PhD Leeds
Computer Officer
Visiting Fellows
Ray Arnhold
Dr Nicholas Armstrong, B.App.Sc (Hons 1st), PhD UTS
Laboratory Manager
Dr Joseph John Brophy, BSc, PhD DSc UNSW, DipEd Monash, CChem, FRACI
Honorary Associate Professors A/Prof. Roger Read, BSc PhD Syd., DIC Lond., CChem, FRACI A/Prof. Gary David Willett, BSc PhD LaT, CChem, MRACI
Adjunct Senior Lectuer Dr. Alex Falber, Algae Enterprises Ltd, Victoria, Australia
International Visiting Fellows Prof. Richard A. Andersen, University of California, Berkeley A/Prof. Suzanne Blum, University of California, Irvine A/Prof. Rohan Davis, Eskitis Institute Griffith University Dr Sam Gerwitz, Bristol Meyers Squibb Ms Xiaopei Hou, Precision Medical Device Department, Shanghai Medical Instrument College (SMIC), China Prof. Eric Jacobsen, Harvard University Dr Damia Mawad, Imperial College – London, UK
Dr Toby Jackson
Technical Officers Linh Cuba-Chiem, BSc (Hons), PhD UniSA Peta Di Bella, BSc (Hons) UQ Hitendra Gopal Berta Litvak, BSc UTS, MEdAdmin UNSW Michael McMahon Dr Nancy Scoleri, BSc (Hon), PhD Adel. Svetislav Videnovic, BChemEng, Sarajevo
School Store Ian Aldred Rama Anning
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Invited Lectures & Conference Presentations – Emeritus & Visiting Fellows
Emeritus Professor Roger Bishop Invited Lecture, 7th International Conference on Materials for Advanced Technologies (ICMAT 2013), Unusual solvent cooperation that is essential for clathrate inclusion compound formation, Singapore, 30 June – 5 July 2013. 21st International Conference on the Chemistry of the Organic Solid State (ICCOSS XXI), Unusual solvent cooperation in clathrate inclusion compound formation, Oxford, UK, 4-9 August 2013.
Emeritus Professor D. Brynn Hibbert Report of Division V (Analytical Division), IUPAC General Assembly, Istanbul, August 2013. How to win Grants, RACI Consultants Group, Sydney, December 2013.
Professorial Visiting Fellow, Ron Postle Invited lecture. ‘Tristimulus Dimensions of Knitted Fabric Tactile Properties: A Soft Matter Case Study’. Asia Textile Conference ATC12, Federation Asian Professional Textile Associations, FAPTA, Shanghai, October 2013. Invited presentation, The Fiber Society (USA) meeting, Geelong, May 2013. Invited Professor, lecture courses and examinations, University of Haute Alsace, ENSISA, Mulhouse, France, Jan 2013 and Dec 2013: Mechanics and Modelling of Soft Materials, Ecole Doctorale, Ecole Nationale Superieure des Ingenieurs Sud Alsace; PhD qualifying entrance, Masters degree; Undergraduate degree courses for Mechanical Engineering and Textile Engineering students.
Awards: Prize for Outstanding Contribution to FAPTA, Federation Asian Professional Textile Associations, presented at the Asia Textile Conference, Shanghai, October 2013.
Honorary Associate Professor Roger Wayne Read A/Prof Roger Read is the current President of the Royal Australian Chemical Institute NSW Branch. 17th European Symposium on Fluorine Chemistry, Paris, France, 21 – 25 July 2013. Oral presentation: Versatility in the Functional Properties of Fluorous Triazoles and Tetrazoles, D. V. Francis, J. B. Harper, A. I. Mohammed, R. W. Read, presented by R. W. Read. The Scott E. Denmark Symposium. ‘A Celebration of Science by the Denmark Group’, University of Illinois at Urbana-Champaign, Urbana IL, USA, 3 August 2013. Invited lecture: Exploiting Fluorous Heterocycles : Tales/ Tails of Fluorousness, by R. W. Read. Mini-Symposium on Fluorine Chemistry, UNSW, 15 August 2013. Invited lecture: Versatility in the Functional Properties of Fluorous Triazoles and Tetrazoles, by D. V. Francis, J. B. Harper, A. I. Mohammed, R. W. Read, presented by R. W. Read. Southern Highlands Conference on Heterocyclic Chemistry, Bowral NSW, 25 – 27 August 2013. Poster presentation: Cooperativity of Fluorous Triazoles Demonstrated Through their Acid Titration, by D. V. Francis, J. B. Harper, R. W. Read, presented by R. W. Read. Humboldt Colloquium. Looking to the Future – International Research in a Changing World, Sydney, 17 – 19 October 2013. Invited lecture: Applications of Fluorine Chemistry: Fluorous Tales, by R. W. Read. CSIRO Materials Science & Engineering Seminar, Clayton VIC, 21 October 2013. Invited lecture: Probing Function in Small Molecule Fluorous Heterocycles, by R. W. Read. Australian Science Media Centre (AusSMC), Adelaide SA, 24 October 2013. Six items of Australian media coverage of an evacuation caused by a chemical hazard at the University of Technology Sydney on 24 October 2013, in which I was quoted.
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Publications & Patents
Dr Leigh Aldous ‘Electrochemistry of chloride in ambient room temperature ionic liquids: Formation of oxychloride species’ M. M. Hossain, E. Hosseini Bab Anari and L. Aldous, Electrochemistry Communications 2013, 34, 331-334. ‘Oxygen Reduction Reaction in Room Temperature Protic Ionic Liquids’ A. Khan , X. Lu , L. Aldous and C. Zhao, Journal of Physical Chemistry C 2013, 117, 18334-18342 Patent: ‘Method for Shelling Nuts’ W. X. Teh, M. M. Hossain, L. Aldous, Aust. Pat. App. No. 2013904811.
Dr Graham E. Ball Patel, A. R.; Ball, G; Hunter, L.; Liu, F. “Conformational regulation of substituted azepanes through selective monofluorination” Org. Biomol. Chem., 2013, 11, 37813785. Chan, B.; Ball, G.E. “A Benchmark Ab Initio and DFT Study of the Structure and Binding of Methane in the σ–alkane complex CpRe(CO)2(CH4)” J. Chem. Theory Comput. 2013, 9, 2199-2208.
Emeritus Professor Roger Bishop Suryanti V, Bhadbhade M, Bishop R, Black DS, Kumar N, Chirality of the molecular assembly determined by intra-/inter- N-H...O hydrogen bonding in doubly substituted N-octanoylglyoxylic amides, Tetrahedron, 69, 84468455 (2013).
Gao J, Bhadbhade MM, Bishop R, Polymorphic crystals formed by an achiral diol under ambient conditions, Crystal Growth & Design, 12, 5746-5756, in Virtual Special Issue # 9 In honour of Prof. Gautam R. Desiraju, Volume vi, Issue 9, October 4, 2013.
Professor David St Clair Black Somphol, K., Chen, R., Bhadbhade, M., Kumar, N. and Black, D. StC., A new strategy for calixindole formation: synthesis of a calix[3]indole with 2,2; 7,2; 7,7-methylene linkages and a new calix[4]indole with 2,2; 7,2; 7,7; 2,7-methylene linkages, Synlett, 24-28 (2013). Kandemir, H., Wood, K., Kumar, N. and Black, D. StC., Synthesis of 5-(7’-indolyl)oxazoles and 2,5-di(7’-indolyl)oxazoles, Tetrahedron, 69, 2193-2198 (2013). Brimble, M. A., Black, D. StC., Hartshorn, R., Rauter, A. P., Sha, C-K. and Sydnes, L. K., Rules for abbreviation of protecting groups, Pure Appl. Chem., 85, 307-313 (2013). Yee, E. M. H., Pasquier, E., Iskander, G., Black, D. StC. and Kumar, N., Synthesis of novel isoflavene-propranolol hybrids as anti-tumor agents, Bioorganic and Medicinal Chemistry, 21, 16521660 (2013). Suryanti, V., Bhadbhade, M., Bishop, R., Black, D. StC., Kumar, N., Chirality of the molecular assembly determined by intra-/inter- N-H···O hydrogen bonding in doubly substituted N-octanoylglyoxylic amides, Tetrahedron, 69, 8317-8534 (2013).
Chen, R., Somphol, K., Bhadbhade, M., Kumar, N. and Black, D. StC., Synthesis of semi-calix[4]indoles containing combinations of direct links and methylene linkages, Synlett, 14971500 (2013). Nisar, B., Raza, A. R., Black, D. StC., Kumar, N., Tahir, M. N., Stereoselective synthesis of (3R)-3-alkyl-4,1-benzoxazepine2,5-diones, Chirality, 25, 865-870 (2013). Kutty, S. K., Barraud, N., Pham, A., Iskander, G., Rice, S. A., Black, D. StC. and Kumar, N., Design, synthesis and evaluation of fimbrolide-nitric oxide donor hybrids as antimicrobial agents, J. Med. Chem., 56, 9517-9529 (2013).
Dr Joseph J. Brophy Brophy, J.J., Craven, L.A. and Doran, J.C., Melaleucas: Their botany, essential oils and utilization. ACIAR publication No. 156, 415pp ACIAR, Canberra (2013). Lum, B.J., Hibbert, D.B., Brophy, J.J., Identification of substituted cathinones (b-keto phenethylamines) by heptafluorobutyric anhydride (HFBA) chemical derivatization and gas chromatography mass spectrometry. SWAFS Journal, 34 7-30 (2013). Ford, A.J., Craven, L.A. and Brophy, J.J. A new species of Melaleuca (Myrtaceae) from northeastern Queensland. Telopea, 15, 185-189 (2013).
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Professorial Visiting Fellow, Alan Buckley Skinner, W.M., Qian, G., Buckley, A.N. Electronic environments in Ni3Pb2S2 (shandite) and its initial oxidation. J. Solid State Chem., 206 (2013) 32-37. Buckley, A.N., Parker, G.K. Adsorption of n-octanohydroxamate collector on iron oxides. Int. J. Mineral Proc., 121 (2013) 70-89.
Associate Professor Stephen Boyd Colbran McSkimming, A; Colbran S. B., The coordination chemistry of organo-hydride donors: new prospects for efficient multielectron reduction, Chemical Society Reviews, 2013, 42, 5439–5488. McSkimming, A.; Bhadbhade, M. M.; Colbran S. B., Hydride ioncarrier ability in Rh(I) complexes of a nicotinamide-functionalised N-heterocyclic carbene ligand, Angewandte Chemie International Edition, 2013, 52(12), 3411–3418 (front cover). Gilbert-Wilson, R.; Field, L. D.; Colbran, S. B.; Bhadbhade, M. M. Low oxidation state iron(0), iron(I), and ruthenium(0) dinitrogen complexes with a very bulky neutral phosphine ligand, Inorganic Chemistry, 2013, 52, 3043–3053. Tan, T.; Gimbert-Suriñach, C; Bhadbhade, M. M.; Colbran S. B., Flexible dinucleating N,N,Ntridentate ligands based on a xanthene scaffold, Inorganica Chimica Acta, 2013, 399, 55–61. Shrestha, S.; Bhadbhade, M. M.; Gimbert-Surinach, C; Colbran S. B., A dimer of bis(N-heterocyclic carbene)rhodium(I) centres spanned by a dibenzo-18crown-6 bridge from synchrotron radiation, Acta Crystallographica E, 2013, 69(1), m47–48..
Associate Professor Marcus Lawford Cole Cole, ML; Deacon, GB; Junk, PC; Konstas, K; Wang, J, Bittig, H; Werner, D: Synthesis, Structures
and Reactivity of Lanthanoid(II) Formamidinates of Varying Steric Bulk, Chem. Eur J., 2013, 19, 1410-1420. Cole, ML; Hibbert, DB; Kehoe, EJ: Students’ Perceptions of Using Twitter To Interact with the Instructor during Lectures for a Large-Enrolment Chemistry Course, J. Chem. Ed., 2013, 90, 671-672. Cole, ML; Deacon, GB; Junk, PC; Wang, J: Bulky FormamidinateSupported Lanthanoid Halides and Alkyls, Including a Rare Terminal La−Me Species, Organometallics, 2013, 32, 13701378. Bruce, MI; Cole, ML; Costuas, K; Ellis, BG; Kramarczuk, KA; Lapint, C; Nicholson, BK; Perkins, GJ; Skelton, BW; White, AH: Z. Anorg. Allg. Chem., 2013, 639, 22162223. McConnell, JR; Rananaware, DP; Ramsey, DM; Buys, KN; Cole, ML; McAlpine, SR: A potential rhodium cancer therapy: Studies of a cytotoxic organorhodium(I) complex that binds DNA, Bioorg. Med. Chem. Lett., 2013, 23, 25272531.
Dr William Alex Donald W. A. Donald,*G. N. Khairallah, R. A. J. O’Hair, The Effective Temperature of Ions Stored in a Linear Quadrupole Ion Trap Mass Spectrometer, Journal of the American Society for Mass Spectrometry (2013) 24, 811. T. G. Flick,. W. A. Donald, E. R. Williams, Electron Capture Dissociation of Trivalent Metal Ion-Peptide Complexes, Journal of the American Society for Mass Spectrometry (2013) 24, 193. W. A. Donald, E. R. Williams, Measuring Absolute Single Half-cell Reduction Potentials with Mass Spectrometry, in Electroanalytical Chemistry Series, Vol. 25; edited by Zoski, C. G. and Bard, A. J. 2014, p 1-32. M. G. Leeming, J. M. White, R. A. J. O’Hair, W. A. Donald,* Mobile proton triggered radical fragmentation of nitroarginine containing peptides, Journal
of the American Society for Mass Spectrometry (2014) DOI: 10.1007/s13361-013-0794-7
Professor Leslie D. Field Leslie D. Field, Peter M. Jurd, Alison M. Magill, Mohan M. Bhadbhade, Reactions of CO2 and CS2 with [RuH(h2-PCH2Me2) (PMe3)3], Organometallics, 2013, 32(2), 636-642. Leslie D. Field, Hsiu L. Li, Scott J. Dalgarno, Ruaraidh D. McIntosh, Base-Induced Dehydrogenation of Ruthenium Hydrazine Complexes, Inorg. Chem., 2013, 52(3), 1570-1583. Ryan Gilbert-Wilson, Leslie D. Field, Stephen B. Colbran, Mohan M. Bhadbhade, Low Oxidation State Iron(0), Iron(I), and Ru(0) Dinitrogen Complexes with a Very Bulky Neutral Phosphine Ligand, Inorg. Chem., 2013, 52(6), 30433053.
Scientia Professor J. Justin Gooding A. Tregubov, K. Vuong, Khuong, E. Luais, J.J. Gooding, B.A. Messerle, Rh(I) Complexes Bearing N,N and N,P Ligands Anchored on Glassy Carbon Electrodes: towards Recyclable Hydroamination Catalysts, J. Am. Chem. Soc. 135 16429−16437 (2013). A. Barfidokht, S. Ciampi, E. Luais, N. Darwish, J.J. Gooding, The Influence of Organic Film Morphology on the Efficient Electron Transfer at Passivated Polymer Modified Electrodes to which Nanoparticles are Attached, ChemPhysChem 14 2190-2197 (2013). C. Fairman, J.Z. Ginges, S.B. Lowe, J.J. Gooding, Protein Resistance of Surfaces Modified with Oligo(Ethylene Glycol) Aryl Diazonium Derivatives, ChemPhysChem 14 2183-2189 (2013). Y. Zhu, B. Gupta, B. Guan, S. Ciampi, P.J. Reece, J.J. Gooding, A Photolithographic Strategy for Patterning Preformed, Chemically Modified, Porous Silicon Photonic Crystal using Click Chemistry,
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ACS Appl. Mater. Interfaces 5 6514-6521 (2013). K. Guo, S. Freguia, P.G. Dennis, X. Chen, B.C. Donose, J. Keller, J. Gooding, K. Rabaey, The effects of surface charge and hydrophobicity on anodic biofilm formation, community composition and current generation in bioelectrochemical systems, Env. Sci. Tech. 47 7563-7570 (2013). B.S. Flavel, M. Jasieniak, L. Velleman, S. Ciampi, E. Luais, H.J. Griesser, J.G. Shapter, J.J. Gooding, Grafting of poly(ethylene glycol) on click chemistry modified Si(100) surfaces, Langmuir 29 8355-8362 (2013).
229. D.D. Liana, B. Raguse, L. Wieczorek, G.R. Baxter, K. Chuah, J.J. Gooding, E. Chow, Sintered Gold Nanoparticles as an Electrode Material for PaperBased Electrochemical Sensors, RSC Adv. 3 8683-8691 (2013). S.H. Ngalim, A. Magenau, Y. Zhu, Z. Fairjones, J.J. Gooding, T. Böcking, K. Gaus, Creating Adhesive and Soluble Gradients for Imaging Cell Migration with Fluorescence Microscopy. J. Vis. Exp. 74 e50310 (2013). doi:10.3791/50310
J.R. Peterson, Y. Lu, E. Luais, N.A. Lee, J.J. Gooding, A sandwich ELISA assay for Bisphenol A using small molecule BPAfunctionalized gold nanoparticles, Aust. J. Chem. 66 613-618 (2013). Cover image
A. Gui, H. Yau, D. Thomas, M. Chockalingam, J.B. Harper, J.J. Gooding, Using Supramolecular Binding Motifs to Provide Precise Control Over the Ratio and Distribution of Species in Multiple Component Films Grafted on Surfaces: Demonstration using Electro-chemical Assembly from Aryl Diazonium Salts, Langmuir, 29 4772-4781 (2013).
A.L. Gui, E. Luais, J.R. Peterson, J.J. Gooding, Zwitterionic Low Impedance Anti-Fouling Coating on Electrodes Functionalized using Aryl Diazonium Salts, ACS Appl. Mater. Interfaces 5 48274835 (2013).
G.Z. Liu, S. Iyengar, J.J. Gooding, An Amperometric Immunosensor based on Gold NanoparticleDiazonium Salt Modified Sensing Interface for Detection of HbA1c in Human Blood, Electroanalysis 25 881-887 (2013).
U.E. Wawrzyniak, P. Ciosek, M. Zaborowski, G. Liu, J.J. Gooding, Gly-Gly-His Immobilized On Monolayer Modified Back-Side Contact Miniaturized Sensors for Complexation of Copper Ions, Electroanalysis 25 1461-1467 (2013).
S.M. Khor, P. Thordarson, J.J. Gooding, The Impact of AntibodyEpitope Affinity Strength on the Sensitivity and Specificity of Electrochemical Immunosensors for Detecting Small Molecules, Anal. Bioanal. Chem. 405 38893898 (2013).
B. Gupta, Y. Zhu, B. Guan, P.J. Reece, J.J. Gooding, Porous Silicon as an ideal optofluidics material for biosensing: Emphasis on microfabrication and monitoring cells in vivo and in vitro, Analyst, 138 3593-3615 (2013).
A. Barfidokht, S. Ciampi, E. Luais, N. Darwish, J.J. Gooding, DistanceDependent Electron Transfer at Passivated Electrodes Decorated by Gold Nanoparticles, Anal. Chem. 85 1073-1080 (2013).
S. Ciampi, M. James, M.H. Choudhury, N. Darwish, J.J. Gooding, The Detailed Characterization of Electrochemically Switchable Molecular Assemblies on Silicon Electrodes, Phys. Chem. Chem. Phys. 15 9879-9890 (2013).
Patent: 3. J.J. Gooding, G. Liu, Electrochemical Sensor, Australian International Patent Application, 2006901394; Filing Date: 17/03/2006, PCT/ AU2007/000337. (2007), European patent appl. EP07718585.8 (EP2005161) Licensed. US patent 12/293272 Granted 26/9/11, Australian granted 2007229320 26/4/13
Dr Jason Brian Harper Tanner, E. E. L.; Hawker, R. R.; Yau, H. M.; Croft, A. K.; Harper, J. B.: “Probing the importance of ionic liquid structure: A general ionic liquid effect on an SNAr process”, Org. Biomol. Chem. 2013, 11, 7516-7521. Yau, H. M.; Keaveney, S. T.; Butler, B. J.; Tanner, E. E. L.; Guerry, Max S.; George, S. R. D.; Dunn, M. H.; Croft, A. K.; Harper, J. B.: “Towards solvent-controlled reactivity in ionic liquids” Pure Appl. Chem. 2013, 85, 1979-1990. Tanner, E. E. L.; Yau, H. M.; Hawker, R. R.; Croft, A. K.; Harper, J. B.: “Does the cation really matter? The effect of modifying an ionic liquid cation on an SN2 process”, Org. Biomol. Chem. 2013, 11, 6170-6175. Keaveney, S. T.; Harper, J. B.: “Towards reaction control using an ionic liquid: Biasing outcomes of reactions of benzyl halides”, RSC Advances 2013, 3, 15698-15704. Gui, A.; Yau, H. M.; Thomas, D.; Chockalingam, M.; Harper, J. B.; Gooding, J. J.: “Using Supramolecular Binding Motifs to Provide Precise Control Over the Ratio and Distribution of Species in Multiple Component Films Grafted on Surfaces: Demonstration using Electrochemical Assembly from Aryl Diazonium Salts” Langmuir 2013, 29, 4772-4781..
Emeritus Professor D. Brynn Hibbert Rima Raffoul Khoury, Gordon J. Sutton, D. Brynn Hibbert, Diako Ebrahimi, Measurement and modeling of acid dissociation constants of tri-peptides containing Glu, Gly, and His using potentiometry and generalized multiplicative analysis of variance Dalton Trans., 2013, 42 (8), 2940 – 2947. A. S.-K. Tsang, K. Ingram, J. Keiser, B. Hibbert and M. H. Todd, Enhancing the Usefulness of Cross Dehydrogenative Coupling Reactions with a Removable Protecting Group, Org. Biomol. Chem. 2013
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Gregory E. O’Donnell and D. Brynn Hibbert, A study of the conditions of measurement required to evaluate bias in analytical results illustrated by the use of data from a multi-round, blind-duplicated, proficiency test, Analyst, 2013, 138 (13), 3673 – 3678.
Hu, X.-G.; Hunter, L., “Stereoselectively fluorinated nitrogen heterocycles: a brief survey,” Beilstein Journal of Organic Chemistry 2013, 9, 2696.
Benny J. Lum, D. Brynn Hibbert and Joseph Brophy, Identification of Substituted Cathinones (b-keto phenethylamines) by Heptafluorobutyric Anhydride (HFBA) Chemical Derivatization and Gas Chromatography Mass Spectrometry, SWAFS Journal, 2013, 34, 7 – 30.
Lukmantara, A. Y., Kalinowski, D. S., Kumar, N., Richardson, D. R., (2013) Synthesis and biological evaluation of substituted 2-benzoylpyridine thiosemicarbazones: Novel structure-activity relationships underpinning their antiproliferative and chelation efficacy. Bioorganic & Medicinal Chemistry Letters. 23:967-974.
H. Salouros, G. J. Sutton, J. Howes, D. B. Hibbert and M. Collins, Measurement of Stable Isotope Ratios in Methylamphetamine: A Link to Its Precursor Source, Anal. Chem. 85 (19), (2013) 9400-9408. DOI: 10.1021/ac402316d Not peer reviewed D Brynn Hibbert, Evaluation of Measurement Data: The Role of Measurement Uncertainty in Conformity Assessment, Chemistry International, Vol. 35 (2), March-April 2013. W Tyler Estler and D Brynn Hibbert, JCGM 106:2012 - A new guidance document on measurement uncertainty and conformity assessment, OIML Bulletin, Volume LIV (2) 14 – 16, April 2013. D Brynn Hibbert: Sergio Caroli and Gyula Záray: Analytical techniques for clinical chemistry: methods and applications, Book Review, ACQUAL 2013.
Dr Luke Hunter Patel, A.; Ball, G.; Hunter, L.; Liu, F., “Conformational regulation in substituted azepanes through selective monofluorination,” Organic and Biomolecular Chemistry 2013, 11, 3781. Cheerlavancha, R.; Lawer, A.; Cagnes, M.; Bhadbhade, M.; Hunter, L., “Sequential Deoxyfluorination Approach for the Synthesis of Protected a,β,γTrifluoro-δ-amino Acids,” Organic Letters 2013, 15, 5562.
Associate Professor Naresh Kumar
Dutta, D., Cole, N., Kumar, N., Willcox, M. D. P., (2013) Broad spectrum antimicrobial activity of melimine covalently bound to contact lenses. Investigative Ophthalmology & Visual Science 54(1), 175-182. Somphol, K., Chen, R., Bhadbhade, M., Kumar, N., and Black, D. StC. (2013) A new strategy for calixarene formation: Synthesis of calix[3]indole with 2,2; 7,2; 7,7-methylene linkages and a new calix[4]indole 2,2; 7,2; 7,7; 2,7-methylene linkages. Synlett 24:24-28. Kandemir, H., Wood, K., Kumar, N., and Black, D. StC. (2013) Synthesis of 5-(7′-indolyl)oxazoles and 2,5-di-(7′-indolyl)oxazoles. Tetrahedron 69:2193-2198. Theerthankar, D., Kutty, S., Kumar, N., and Manefield, M, (2013) Pyocyanin facilitates extracellular DNA binding to Pseudomonas aeruginosa influencing cell surface properties and aggregation, PLoS ONE 8(3), e58299. Eugene, M. H., Pasqueir, E., Iskander, G., Black, D. StC., and Kumar, N., (2013) Synthesis of novel isoflavene-propranolol hybrids as anti-tumor agents, Bioorganic &. Medicinal Chemistry. 21(7), 1652-1660. Kutty, S. K., Barraud, N., Pham, A., Iskander, G., Rice, S. A., Black, D., StC.; Kumar, N. (2013) Design, Synthesis, and Evaluation
of Fimbrolide-Nitric Oxide Donor Hybrids as Antimicrobial Agents, Journal of Medicinal Chemistry, 56(23), 9517-9529. Nisar, B., Raza, A. R., Black, D. StC., Kumar, N., Tahir, M. N. (2013) Stereoselective Synthesis of (3R)3-Alkyl-4,1-Benzoxazepine-2,5Diones, Chirality 25(12), 865-870. Chen, R., Somphol, K., Bhadbhade, M., Kumar, N., Black, D. StC. (2013) Synthesis of semi-calix[4]indoles containing combinations of direct links and methylene linkages, Synlett (2013), 24(12), 1497-1500. Lukmantara, A. Y., Kalinowski, D. S., Kumar, N., Richardson, D. R. (2013) Structureactivity studies of 4-phenylsubstituted 2’-benzoylpyridine thiosemicarbazones with potent and selective anti-tumour activity Organic & Biomolecular Chemistry, 11(37), 6414-6425. Suryanti, V., Bhadbhade, M., Bishop, R., Black, D. StC., Kumar, N. (2013) Chirality of the molecular assembly determined by intra-/inter-N-H···O hydrogen bonding in doubly substituted Noctanoylglyoxylic amides, Tetrahedron 69(39), 8446-8455. Ma, C., Yang, X., Kandemir, H., Mielczarek, M., Johnston, E. B., Griffith, R., Kumar, N., Lewis, Peter J. (2013) Inhibitors of bacterial transcription initiation complex formation, ACS Chemical Biology, 8(9), 1972-1980. Sinha, S., Mishra, P., Amin, H., Rah, B., Nayak, D., Goswami, A., Kumar, N., Vishwakarma, R., Ghosal, S. (2013) A new cytotoxic quinolone alkaloid and a pentacyclic steroidal glycoside from the stem bark of Crataeva nurvala: Study of anti-proliferative and apoptosis inducing property, European Journal of Medicinal Chemistry (2013), 60, 490-496. Patents: Kumar, N., Kutty, S.; Barraud, N., Rice, S. Dual action nitric oxide donors and their use as antimicrobial agents. PCT International Application (2013), PCT/AU2013/00/292.
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Willcox, M.D.P.; Kumar, N.; Cole, N. Antimicrobial peptides modified for mammalian cell recognition and/or adhesion. PCT International Application (2013), PCT/AU2013/001176..
Associate Professor Shelli Renee McAlpine
Shelli R. McAlpine*, Organic Letters V15, p3574-3577, 2013 Mechanism of action for a novel macrocycle: a small molecule inhibitor of the ribosome machinery, Worawan Tantisantisom, Deborah M. Ramsey, and Shelli R. McAlpine*, Organic Letters V15, p46384641, 2013
Dual inhibition approaches: modulating hsp70 and hsp90 simultaneously, Yao Wang, Jeanette McConnell, and S. R. McAlpine* in press (Book Chapter accepted by Springer Books: Heat shock protein inhibitors: success stories)
Effectively delivering a drug using star polymers: Improving solubility of a unique hsp90 inhibitor, Seong Jong Kim, Deborah M. Ramsey, Cyrille Boyer, Thomas Davis, and Shelli R. McAlpine*, ACS Med. Chem. Lett V4, p915-920, 2013
Hsp90 inhibitors: modulating the N-versus the C-terminal domain, Jeanette McConnell, Yao Wang and S. R. McAlpine* in press (Book Chapter accepted by Springer Books: Heat shock protein inhibitors: success stories)
Novel Marine Natural Products that target the gram-positive Cell Wall Deborah M. Ramsey,* Amirul Islam, Rohan A. Davis, Cynthia B. Whitchurch, Lynne Turnbull and Shelli R. McAlpine, Bioorg. & Med. Chem Lett. V23, p48624866, 2013
Synthesis and cytotoxicity of sanguinamide B analogs: identification of an active macrocyclic conformation, Hendra Wahyudi, Worawan Tantisantisom, and Shelli R. McAlpine*, In press Tetrahedron Lett. Jan 2nd, 2014
A potential Rhodium Cancer Therapy: studies of a cytotoxic organorhodium (I) complex that binds DNA, Jeanette R. McConnell, Dimple P. Rananaware, Deborah M. Ramsey, Kai N. Buys, Marcus L. Cole and Shelli R. McAlpine*, Bioorg. & Med. Chem Lett. V23, p2527-2531 2013
Recent Advances in Macrocyclic Hsp90 Inhibitors, Deborah Ramsey, R.R. A Kitson, J. I Levin, C. J Moody*, and S. R. McAlpine*, Book Chapter accepted by RSC Books: Macrocycles in Drug Discovery A Heat shock protein 90 inhibitor that modulates the immunophilins and regulates hormone receptors without inducing a heat shock response, Jeanette R. McConnell, Leslie D. Alexander, and Shelli R. McAlpine*, Bioorg. & Med. Chem Lett. V24, p661-666, 2014 Utilizing a Dimerization strategy to inhibit the dimer protein Hsp90: Synthesis and biological activity of a sansalvamide A dimer, Hendra Wahyudi, Yao Wang, and Shelli R. McAlpine*, Org. Biomol. Chem. V12, p765-773 2014 Total synthesis and biological activity of the natural product Urukthapelstatin A, Chun Chieh Lin, Worawan Tantisantisom, and
Heat shock proteins 27, 40, and 70 as combinational therapeutic targets, Jeanette R. McConnell and Shelli R. McAlpine*, Bioorg. & Med. Chem. Lett. V23, p19231928, 2013 An efficient synthetic route for synthesizing macrocycles that contain heterocycles: Solid Phase versus Solution Phase Synthesis, Seong Jong Kim and Shelli R. McAlpine*, Molecules V18 p11111121 2013 A structure-activity relationship study on multi-heterocyclic molecules: two linked thiazoles are required for cytotoxic activity, Seong Jong Kim, Chun Chieh Lin, Chung-Mao Pan, Dimple P. Rananaware, Deborah M. Ramsey, and Shelli R. McAlpine*, Med. Chem. Comm. V4 , p406410, 2013
Halting Metastasis through CXCR4 inhibition, Deborah M. Ramsey* and Shelli R. McAlpine*, Bioorg.& Med. Chem. Lett. V23, p20-25, 2013. Patents: A novel small molecule that blocks the ribosomal inhibitor, (UNSW), disclosure filed 2013 Using both hsp70 and Hsp90 inhibitors to target resistant cancers, (UNSW), disclosure filed 2013 Hsp90 inhibitor attached to a nanoparticle, (UNSW), S. J. Kim, D. Ramsey, C. Boyer, T. Davis S. R. McAlpine, Patent Application: Application number 2013902460
Professor Barbara Anne Messerle Andrey A. Tregubov, Khuong Q. Vuong, Erwann Luais, J. Justin Gooding, and Barbara A. Messerle* Rh(I) Complexes Bearing N,N and N,P Ligands Anchored on Glassy Carbon Electrodes: towards Recyclable Hydroamination Catalysts, Journal of the American Chemical Society, 2013, 135 (44), 16429– 16437 Sandra W. S. Choy, Michael J. Page, Mohan Bhadbhade and Barbara A. Messerle*, Cooperative Catalysis: Large Rate Enhancements with Bimetallic Rhodium Complexes, Organometallics, 2013, 2013, 32 (17), 4726–4729. Khuong Q. Vuong, Marina Timerbulatova, Matthew B. Peterson, Mohan Bhadbhade and Barbara A. Messerle*, Cationic Rh and Ir complexes containing bidentate Imidazolylidene-1,2,3triazole donor Ligands: Synthesis and preliminary Catalytic Studies, Dalton, 2013, 42, 14298-14308 Marina Timerbulatova, Mark Gatus, Khuong Vuong, Mohan Bhadbhade, Andrés G. Algarra, Stuart A. Macgregor* and Barbara A. Messerle*, Bimetallic Complexes for Enhancing Catalyst Efficiency – Probing the Relationship between Activity
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and Intermetallic Distance, Organometallics, 2013, Organometallics, 2013, 32 (18), 5071–5081. Bradley Y.-W. Man, Astrid Knuhtsen, Michael J. Page and Barbara A. Messerle*, Directing the Regioselectivity of Rhodium(I) Catalysed Cyclisation of 2-Alkynyl Benzoic Acids, Polyhedron, 2013, 61, 248–252.
Associate Professor Jonathan Charles Morris Southam, D. C.; Shand, B.; Buntine, M. A.; Kable, S. H.; Read, J. R.; Morris, J. C “The timing of an experiment in the laboratory program is crucial for the student laboratory experience: acylation of ferrocene as a case study”, Chem. Educ. Res. Pract. 2013, 14, 476. Morris, J. C. “Marine Natural Products: Synthetic Aspects”, Nat. Prod. Rep. 2013, 30, 783. , Collison, A.; Hatchwell, L.; Verrills, N.; Wark, P.A.B; de Siqueira, A.P.; Tooze, M.; Carpenter, H.; Don, A.S.; Morris, J.C.; Zimmermann, N.; Bartlett, N.W.; Rothenberg, M.E.; Johnston, S.L.; Foster, P.S.; Mattes, J. ‘The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirusinduced asthma by inhibiting protein phosphatase 2A activity’, Nature Medicine, 2013, 19, 232.
Professorial Visiting Fellow, Ron Postle Wai-yin Wong, Jimmy Kwok – Cheong Lam, Chi-wai Kan and Ron Postle. ‘Influence of Knitted Fabric Construction on the Ultraviolet Protection Factor of Greige and Bleached Cotton Fabrics’. Textile Research Journal, 83, No. 7, May 2013, pp 683-699. M.Tsukada, M.M.R. Khan, T.Miura, R.Postle and A.Sakaguchi. Mechanical Performance of Wool Fabrics Grafted with Methacrylamide and 2-Hydroxyethyl Methacrylate by the Kawabata Evaluation System for Fabrics. Textile Research J, 83 (12) July 2013
pp 28-35. online publication, 11 January 2013, www. textileresearchjournal.com, DOI: 10.1177/0040517512458338. H.M. Wang, T.J. Mahar and R.Postle. Multivariate Analysis of Tactile Sensory Data for Fine Lightweight Knitted Fabrics. Research J of Textile & Apparel, August 2013, 17, No.3, pp 1-12. T.J. Mahar, H.M. Wang and R.Postle. A Review of Fabric Tactile Properties and their Subjective Assessment for Next-to-Skin Knitted Fabrics. J Textile Inst, 2013, 104, No. 6, pp 572 – 589; 15 Mar 2013, http:// www.tandfonline.com, DOI: 10.1080/00405000.2013.774947. H.M. Wang, T.J. Mahar and R.Postle. Instrumental Evaluation of Orthogonal Tactile Sensory Dimensions for Fine Lightweight Knitted Fabrics. J Textile Inst, 2013, vol 104, No. 6, pp 590-599; 15 Mar 2013, www.tandfonline. com, DOI:10.1080/00405000.201 3.773626. R. Postle. ‘Tristimulus Dimensions of Knitted Fabric Tactile Properties: A Soft Matter Case Study’. Asia Textile Conference ATC12 Proceedings, Shanghai, October 2013.
Dr Neeraj Sharma P. Serras, V. Palomares, J. Alonso, N. Sharma, J. M. Lopez del Amo, P. Kubiak, M. L. Fdez-Gubieda, T. Rojo, The electrochemical Na extraction/insertion of Na3V2O2x(PO4)2F3-2x, Chemistry of Materials, 25, 4917-4925 (2013) R. J. Gummow, N. Sharma, R. Feng, G. Han, Y. He, High Performance Composite Lithium-Rich Nickel Manganese Oxide Cathodes for LithiumIon Batteries, Journal of the Electrochemical Society, 160, A1556-A1862 (2013) C. D. Ling, S. A. Schmid, P. E. R. Blanchard, V. Petricek, G. J. McIntyre, N. Sharma, A. Maljuk, A. A. Yaremchenko, V. V. Kharton, M. J. Gutmann, R. L. Withers, A (3 + 3)-Dimensional “Hypercubic” Oxide-Ionic Conductor: Type
II Bi2O3−Nb2O5, Journal of the American Chemical Society, 135, 6477-6484 (2013) W. Brant, S. Schmid, Q. Gu, G. Du, N. Sharma, A simple electrochemical cell for in-situ fundamental structural analysis using synchrotron X-ray powder diffraction, Journal of Power Sources, 244, 109-114 (2013) C.-W. Hu, N. Sharma, C.-Y. Chiang, H.-C. Su, V. K. Peterson, H.-W. Hsieh, Y.-F. Lin, W.-C. Chou, B.-Y. Shew, C.-H. Lee, Real-time investigation of the structural evolution of electrodes in a commercial lithium-ion battery containing a V-added LiFePO4 cathode using in-situ neutron powder diffraction, Journal of Power Sources, 244, 158-163 (2013) N. Sharma, D. Yu, Y. Zhu, Y. Wu, V. K. Peterson, Non-equilibrium structural evolution of the lithium rich Li1+yMn2O4 cathode within a battery, Chemistry of Materials, 25, 754–760 (2013) R. P. Rao, N. Sharma, V. K. Peterson, S. Adams, Formation and conductivity studies of lithium argyrodite solid electrolytes using in-situ neutron diffraction, Solid State Ionics, 230, 72-76 (2013) T. Tao, D. Zhou,H. Zhang, S. Liu, R. Amal,Y. Chen,N. Sharma, A. M. Glushenkov, Expanding the applications of the ilmenite mineral to the preparation of nanostructures: TiO2 nanorods and their photocatalytic properties in the degradation of oxalic acid, Chemistry, A European Journal, 19, 1091-1096 (2013) Y. Wang, N. Sharma, D. Su, D. Bishop, H. Ahn, G. Wang, High capacity spherical Li[Li0.24Mn0.55Co0.14Ni0.07]O2 positive electrode material for lithium ion batteries, Solid State Ionics, 233, 12-19, (2013) N. Sharma, V. K. Peterson, Overcharging a lithium-ion battery: Changes in graphite determined by in situ neutron diffraction, Journal of Power Sources, 244, 695-701 (2013)
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N. Sharma, V. K. Peterson, Current dependency of lattice fluctuations and phase evolution of electrodes in lithium-ion batteries investigated by in situ neutron diffraction, Electrochimica Acta, 101, 79-85 (2013).
Associate Professor John Arron Stride Switchable Magnetism: Neutron Diffraction Studies of The Desolvated Coordination Polymer Co3(OH)2(C4O4)2.; R.A. Mole, J.A. Stride, M.A. Nadeem, J.A. Stride, V. Peterson and P.T. Wood, Inorg. Chem., 2013, 52, 13462-13468. One-pot synthesis of CdS nanoparticles exhibiting quantum size effect prepared within a solgel derived ureasilicate matrix; L.F. Gonçalves, C.R. Silva, F.K. Kanodarwala, J.A. Stride, M.R. Pereira, M.J Gomes, Opt. Mat., 2013, 36, 186-190. Simple metal-catalystfree production of carbon nanostructures; T.K. Ellis, C. Paras, M.R. Hill and J.A. Stride, Aus. J. Chem., 2013, 66, 14351439. Synthesis and characterization of organic-inorganic hybrid materials prepared by solgel and containing ZnxCd1-xS nanoparticles prepared by a colloidal method; L.F.F.F. Gonçalves, F.K. Kanodarwala, J.A. Stride, C.J.R. Silva, M.R. Pereira, M.J.M. Gomes, J. Luminesc., 2013, 144, 203-211.
Associate Professor Pall Thordarson David Hvasanov, Joshua R. Peterson and Pall Thordarson, Self-assembled light-driven photosynthetic-respiratory electron transport chain hybrid proton pump. Chemical Science, 2013, 4, 3833-3838 (back cover article). David Hvasanov, Alexander F. Mason, Daniel C. Goldstein, Mohan Bhadbhade and Pall Thordarson, Optimising the synthesis, polymer membrane
encapsulation and photoreduction performance of Ru(II)- and Ir(III)-bis(terpyridine) cytochrome c bioconjugates. Organic & Biomolecular Chemistry, 2013, 11, 4602-4612 (inside cover article). Daniel C. Goldstein, Joshua R. Yuen Yap Cheng, Raphael G. C. Clady, Timothy W. Schmidt and Pall Thordarson, Synthesis and Luminescence Properties of Iridium(III) Azide and TriazoleBisterpyridine Complexes. Molecules, 2013, 18, 8959-8975. Nageshwar R.Yepuri, Scott A. Jamieson, Tamin A. Darwish, Aditya Rawal, James M. Hook, Pall Thordarson, Peter J.Holden, Michael James, Synthesis of per-deuterated alkyl amines for the preparation of deuterated organic pyromellitamide gelators. Tetrahedron Letters, 2013, 54, 2538-2541. Ya-Na Wu, Ping-Ching Wu, LiXing Yang, Kyle R. Ratinac, Pall Thordarson, Kristina A. Jahn, Dong-Hwang Chen, Dar-Bin Shieh and Filip Braet, The anticancer properties of iron core-gold shell nanoparticles in colorectal cancer cells. International Journal of Nanomedicine, 2013, 8, 33213331. Sook Mei Khor, Pall Thordarson and J. Justin Gooding, The Impact of Antibody-Epitope Affinity Strength on the Sensitivity of Electrochemical Immunosensors for Detecting Small Molecules, Analytical and Bioanalytical Chemistry, 2013, 405, 3889-3898.
Dr Chuan Zhao Xunyu Lu, Yun Hau Ng and Chuan Zhao*, Gold nanoparticles embedded within mesoporous cobalt oxide enhance electrochemical oxygen evolution, ChemSusChem, accepted, published online 10/12/13 Changlong Xiao, Alexander Weremfo and Chuan Zhao*, Electrochemical determination of water in organic solvents using a gold electrode, Electroanalysis, accepted
Zhan-Gang Han, Xiao-Qing Chang, Kai-Ning Gong, JinShuang Yan, Chuan Zhao and Xue-Liang Zhai, An unusual metallic-oxygen cluster consisting of a {AlMo12O40(MoO2)}, Inorg. Chem., 2014, 53, 670−672 Chuan Zhao*, Changlong Xiao, Hubert M. Chan and Xunyu Lu, Decorating semiconductor silver-tetracyanoquinodimethane nanowires with silver nanoparticles from ionic liquids, Aus. J. Chem., in press Sikun Cheng, Yanhua Dong, Yayan Wu, Junfeng Song and Chuan Zhao*, A sensitive catalytic wave formed by electrochemical reduction of morin in the presence of an oxidant KIO3, Aus. J. Chem., In press Xunyu Lu and Chuan Zhao*, One-pot, all electrochemical intercalation, exfoliation and in situ nitrogen doping of graphite in nitrate-based protic ionic liquids,
Phys. Chem. Chem. Phys., 2013, 15 (46), 20005 – 20009 Bryan Suryanto, Xunyu Lu and Chuan Zhao*, Layer-bylayer assembly of transparent amorphous Co3O4 nanoparticles/ graphene composite electrodes for sustained oxygen evolution reaction, J. Mater. Chem. A, 2013, 1, 12726-12731 Cover Front Article Xunyu Lu and Chuan Zhao*, Highly efficient and robust oxygen evolution catalysts achieved by anchoring nanocrystalline cobalt oxides onto mildly oxidized multiwall carbon nanotubes, J. Mater. Chem. A, 2013, 1(39), 12053-12059 Asim Khan, Xunyu Lu, Leigh Aldous and Chuan Zhao*, Oxygen reduction reaction in room temperature protic ionic liquids, J. Phys. Chem. C, 2013, 117 (36), 18334-18342. Patents Chuan Zhao, Xunyu Lu, “Carbon catalyst materials”, Australian Patent AU2013904656, filed on 2 Dec 2013 Chuan Zhao, Xunyu Lu, “Stable and more efficient carbon electrodes”, International Patent Application PCT/AU2013/001148
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Grants and Research Fellowships
AUSTRALIAN RESESARCH COUNCIL Discovery Projects (new & continuing funding) Investigator(s)
$
Project
Prof. JJ Gooding
180,000
Making Silicon Even More Useful: Functionalising Silicon to Produce Stable Electronic Devices in Aqueous Environments
Prof. D.B. Hibbert
100,000
Maximum entropy methods for Bayesian analysis in chemistry
Prof. JJ Gooding, PJ Reece (Physics)
180,000
Smart surfaces for monitoring cellular activity in real time: from multiple to single cells
Prof. A.F. Hill, Prof. B.A. Messerle
100,000
Boron and silicon based pincer ligands for environmentally responsible catalysis
Dr C. Zhao
130,000
A/Prof M.L. Cole A/Prof. P Thordarson, Dr C. Zhao Prof D. Young, Prof. D.B Hibbert, A/Prof Zhao,
Tuning the electrolytes for high efficiency star splitting of water
60,000
Thallium Hydride Complexes – Synthesis, stabilisation and synthetic Utility
100,000
Photochemical and Electrochemical Control of Redox Enzyme Cascades
95,000
Heat-resisting iron-nickel base alloys in challenging new applications – oxygen permeabilities and resistance to internal oxidation (New)
120,000
Getting the reaction outcomes you want: Towards solvent-controlled reactivity using ionic liquids. (New)
110,000
A new metallo-protein inspired methodology for energy efficient chemical reduction. (New)
Prof. B.A. Messerle, Prof. S.B. Duckett
130,000
Turning homogeneous catalysts into heterogeneous catalysts: Robust linking of organometallic complexes onto inert carbon supports (New)
A/Prof P. Thordarson
110,000
How are self-assembled gels formed? From trial-and-error to rational molecular design (New)
Dr J. B. Harper, Dr L. T. Scott A/Prof. SB Colbran, Prof. LD Field, E Nordlander, Dr GE Ball
Linkage Program (new & continuing funding) Investigator(s)
$
Project
Prof. J.J. Gooding & S Iyengar (AgaMatrix Inc)
62,500
New strategies for characterising and monitoring protein-surface interactions: application to a biosensor for diabetic’s blood glucose regime effectiveness
Prof. N. Kumar, M. Willcox, N. Cole
95,000
Antimicrobial contact lens cases
M. Willcox, Prof. N. Kumar, N. Cole, N. James
80,000
Novel antimicrobial surface coatings for biomedical applications
Prof J.J. Gooding, Prof T.P. Davis, Prof M. Kavallaris
87,500
The development of tuneable materials to allow the threedimensional printing of cells
A/Prof. P. Thordarson, Dr J.M. Hodgkiss, Dr A. Falber
51,000
Controlling light-harvesting with complex perylene arrays (New)
Dr C. Zhao, et al
26,700
Chip-Scale Implantable Bionics for Next Generation Therapeutic Neural Prostheses arrays (New)
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Industrial Transformation Training Centre (new & continuing funding) Investigator(s) Prof. J.J. Gooding & 19 others
$ 700,000
Project Training Centre for Advanced Technologies in Food Manufacture
Discovery Early Career Researcher Award (new & continuing funding) Investigator(s)
$
Project
Dr W.A. Donald
125,000
Strike while the iron is hot – Structure and reactivity of Fe-oxo complexes that mimic C-H bond activating enzymes (New)
Dr R. Linser
125,000
Membrane protein function in its native lipid environment characterised by solid state nuclear magnetic resonance (New)
Dr L. Hunter
125,000
Flurinated amino acids: building blocks for the synthesis of shapecontrolled bioactive peptides (New)
Dr L. Aldous
108,000
‘Lignin in Ionic Liquids: Electrochemical approaches towards Delignification and Depolymerisation (New)
Future Fellowship (new & continuing funding) Investigator(s)
$
Project
A/Prof. Thordarson, P.
205,714
Moving Supramolecular Assembly of Functional Systems into Water (New)
Prof. T.W. Schmidt
108,872
Nanostructured upconvertors for advanced solar energy harvesting (New)
NATIONAL HEALTH & MEDICAL RESEARCH COUNCIL Investigator(s)
$
Project
Prof. J.J. Gooding, A/Prof. N. Di Girolamo, Prof. D. Wakefield
139,925
A nanomedicine strategy for detecting and modulating protease activity in vivo
A/Prof S.R. McAlpine
147,998
Developing novel molecules that target hormone receptors as an alternative cancer therapy (New)
UNSW australia GRANTS Faculty Research Grants Investigator(s)
$
Project
Dr Leigh Aldous
10,000
Exploiting the Unique Surface-Structure of Ionic Liquids: Monitoring the Volatilisation of Volatile Organics from Non-Volatile Ionic Liquids
Dr Graham Ball
10,000
Metal-alkane complexes: are they stable enough to be isolated?
A/Prof. Jonathan Morris
24,000
Target- and Diversity-Oriented Approaches to the Development of Biologically Active Scaffolds
A/Prof John Stride
18,200
MOFs – A New Area for Medicine?
A/Prof. Stephen Colbran
8,000
Towards a practical synthesis of formic acid from atmospheric carbon dioxide
88 / annual report
Major Research Equipment and Infrastructure Scheme Investigator(s)
$
Project
A/Prof P.Thordarson, Dr J. Harper, Dr W.A. Donald et al
$395,000
Maldi Tof/Tof for Biological and Chemical Analysis
A/Prof S. McAlpine, Prof. N. Kumar, A/Prof P.Thordarson, et al
$90,000
Twin-preparative HPLC system
Prof. N. Kumar, Dr L. Hunter, A/Prof P.Thordarson, et al
$60,000
Circular Dichroism Spectrometer
Early Career Researcher Investigator(s)
$
Dr Jonathon Beves
15,000
Using Light to Control pH
15,000
Energy solutions: Investigating sodium-ion battery technology for large-scale energy storage
Dr Neeraj Sharma
Project
Goldstar Investigator(s)
$
Project
Kumar N
$40,000
Antimicrobial biomaterials to reduce implant related bacterial infections
AUSTRALIAN GRANTS Investigator(s)
$ 10,000,000
Prof Ron Postle, et al
(2007 â&#x20AC;&#x201C; 2014)
Project
Source
CRC for Sheep Industry Innovation
Australian Wool Testing Authority, CSIRO & The University of California
Developing improved materials for energy generation and storage
Australian Institute of Nuclear Science and Engineering
Dr N. Sharma
$95,999
Prof N. Kumar; Prof. M. Willcox; Dr N.Cole
$30,000
Prof. J.J. Gooding
20,417
Towards single cell isolations
Australian Institute of Nuclear Science and Engineering
Prof. T.W. Schmidt
9,000
Deuteration for advanced optical materials
Australian Institute of Nuclear Science and Engineering
A/Prof. P. Thordarson
25,000
The supramolecular chemistry of natural sweeteners
Neptune Bio-Innovations
A/Prof. P. Thordarson
5,000
Peptide self assembly systems for delivery applications
CSIRO
Honorary A/Prof R.W. Read
$15,000
Characterisation of Triodia resin extracts for construction industry applications
NSW Government TechVoucher Scheme
A/Prof P. Thordarson, Dr A. Falber
45,376
Development of Fluorescent media to enhance nutritional algae growth
Researcher in Business (RiB)
A/Prof. J. Stride, et al
116,865
Solving the Energy Waste Roadblock
Science and Industry Endowment Fund (SIEF)
Antimicrobial contact lens cases
Intellectual Ventures
INTERNATIONAL GRANTS Investigator(s)
$
Project
Source
AJ Phillips, A/Prof JC Morris, CJ Stephenson
USD$174,500
Robust New Chemistries for Heterocycles
National Institutes of Health
A/Prof S.R. McAlpine
USD$70,906
Conformational based Design and development of antitumor agents
National Institutes of Health
School / 89
90 / annual report
Industry and Community Interaction
Listed below are the companies, government authorities, societies and educational institutions that academic staff interacted with in 2013. Dr Leigh Aldous
Professor Leslie D. Field
PhD examiner for the following institution:
Australian Research Council: Ozreader
Victoria University of Wellington, New Zealand.
Journal reviewer for:
Collaboration with the following companies:
Organometallics
SunRice Australia
Inorganic Chemistry
Micro Milling Pty Ltd
Dalton Transactions
Macadamias Direct.
Journal of the American Chemical Society
Dr Graham Ball Consultant for a legal case brought by the ACCC.
Emeritus Professor Roger Bishop
Nature Chemistry Journal of Organometallic Chemistry Chemical Communications.
Scientia Professor Justin Gooding
Specialised Assessor for the ARC Discovery Projects Scheme.
Consultant for the following companies:
Member of Editorial Advisory Board of Journal of Inclusion Phenomena and Macrocyclic Chemistry.
Inventia Pty Ltd
Member of the International Advisory Committee, International Conference on the Chemistry of the Organic Solid State (ICCOSS).
AgaMatrix Inc.
Dr Jason Brian Harper PhD examiner for the following institution: Monash University
Assessor for the National Research Foundation of South Africa (South Africa – Argentina Research Cooperation Programme in Science and Technology).
University of Sydney.
Examiner of MSc thesis for the University of Cape Town, South Africa.
Professor D. Brynn Hibbert
Assessor for the Science Foundation Ireland: Review of Research Professorship Programme Grant application for 5 million Euro, 2013-2018. External Reviewer: Quality Assurance Review of the Centre for Supramolecular Chemistry Research, University of Cape Town, South Africa
University of Melbourne
Legal Opinion: Legal Aid NSW King & Mallesons Norton Rose Elie Rahme & Associates Bannisters Lawyers
Professorial Visiting Fellow Alan Buckley
One Group Legal
Consultant for the following companies:
Harness Racing NSW
Australian Metallurgical Services Pty Ltd.
Armstrong Legal
Orica Mining Chemicals.
David Cohen Lawyers
Associate Professor Stephen Boyd Colbran PhD examiner for the following institution: ààThe University of Melbourne.
Fonterra Inc. Legal Aid Victoria Potts Lawyers KM Legal Fitzroy Legal
School / 91
Analytical Chemistry consulting:
Professorial Visiting Fellow, Ron Postle
Network Nutrition
PhD examiner for the following institutions:
Troy laboratories Apex laboratories
Ecole Nationale Supériere des Ingeneurs, Sud Alsace, University of Haute Alsace, Mulhouse, France.
Queensland racing
Consultancies / Collaborations:
Other: NSW Department of Environment and Climate Change E-Nose Pty. Ltd. Australian Forensic Drug Laboratory Australian Racing Forensic Laboratory National Measurement Institute NATA Standards Australia Bureau International des Poids et Mesures (BIPM), Sevres, France IUPAC (Vice-President, Division V)
Dr Luke Hunter PhD examiner for the following institution: The University of Adelaide.
Professor Naresh Kumar PhD examiner for the following institution: Australian National University Nanyang Technological University Singapore Sydney University The University of Auckland The University of Newcastle The University of Queensland. Collaborations: Intellectual Ventures Centre for Marine Bio-Innovation
AWTA, Australian Wool Testing Authority, Melbourne. Wool fibre measurement and tactile sensory perception Australian Wool Innovation, AWI and University of California, Davis, USA. Development and calibration of PhabrOmeter instrument for quality control of textile chemical finishing in industry. Research and development for supersoft light-weight textile materials in collaboration with chemical and fibre industries, Textile Machinery Society of Japan, Osaka Development of knitted fabric structures for ultraviolet protection in collaboration with fibre, chemical, textile and apparel manufacturing industries in China and Hong Kong Industry Research and Development, LMPT, Mechanics and Physics Laboratories, CNRS and Louis Pasteur University, University of Strasbourg, France. Medical textile applications: Vascular Graft and Heart Valve Prostheses N. Schlumberger, Guebwiller, Alsace, France on recycling textile and composite materials University of Nancy and Ecole des Mines, Paris. Computer imaging of three-dimensional textile materials and objective specification of large complex deformations. International Scientific Committees: AUTEX (Association European University Textile Departments) annual conference, Bursa, Turkey and Examiner, Simulation and Modeling Section International Textile, Clothing and Design Conference, ITC&DC, University of Zagreb, Dubrovnik (Croatia)
Cochlear Ltd.
International Scientific and Program Committee, International Conference of Applied Research on Textile, CIRAT, Tunisia
Associate Professor Shelli McAlpine
Other:
Lowy Cancer Research Centre
PhD examiner for the following institutions: Westmead Hospital. The University of Sydney
Editorial Boards: Textile Research Journal, USA; International Journal of Clothing Science and Technology, IJCST, UK; Research Journal of Textile and Apparel, Hong Kong.
PhD examiner for the following institutions:
Referee scientific papers for publication in international macromolecular, fibre, polymer, textile, apparel, applied mechanics and composite materials research journals.
Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, India.
Review Government research grant applications for Australia, New Zealand, Hong Kong and France.
Associate Professor Jonathan Morris
Director, Genetic Eye Foundation, Department of Ophthalmology, Prince of Wales Hospital, Sydney.
Professor Barbara Ann Messerle
PhD examiner for the following institutions: University of Auckland. University of Witwatersrand
Life member and former Chairman of Directors, Radio for the Print Handicapped Cooperative NSW Limited (2RPH). Member and former President, Retina Australia.
92 / annual report
Honorary Visiting Associate Professor Roger Read Consultant: Echidna Energy. Referee for the following journals:
Collaborations: Australian Nuclear Science and Technology Organisation Australian Synchrotron Intellectual Ventures.
Australian Journal of Chemistry
Grant Review:
Bioorganic and Medicinal Chemistry Letters
King Fahd University of Petroleum and Minerals
Journal of Organic Chemistry
Australian Nuclear Science and Technology Organisation
Journal of Physical Organic Chemistry Natural Product Reports Molecular Diversity
Australian Synchrotron Australian Research Council.
RSC Advances.
Associate Professor Pall Thordarson
Dr Neeraj Sharma
Consultant & contract research:
PhD examiner for the following institutions: University of Auckland Deakin University.
Associate Professor John Arron Stride PhD examiner for the following institutions: Quaid-i-Azam University.
Algae Enterprise Flurosol Industries Neptune Bio-innovations Sustainability Ventures Grant Review Foundation for Polish Science.
Dr Chuan Zhao Collaboration & Consultantcy: Cochlear Ltd. Zenogen Pty Ltd, Sydney
School / 93
Undergraduate and Postgraduate Enrolments
Enrolment statistics 2013 2007
2008
2009
2010
2011
2012
2013
1575
1495
1521
1844
1966
1966
2445
Second Year
257
256
231
219
336
352
340
Third Year
159
164
182
137
102
187
215
83
84
75
63
80
99
128
741
824
878
898
954
1024
1233
Second Year
74
103
98
94
275
367
330
Third Year
62
40
54
13
75
67
60
*31
*22
25
18
15
*29
*35
11
16
20
30
36
26
26
4
5
12
3
3
2
3
6
2
4
3
4
1
0
ENROLMENTS in CORE CHEMISTRY COURSES First Year
Level III CHEM electives ENROLMENTS in SERVICE COURSES First Year
Honours
Total POSTGRADUATE COURSEWORK STUDENTSe Master of Science and Technology (Program 8708) Graduate Diploma (Program 5648) Graduate Certificate (Program 7428) POSTGRADUATE RESEARCH STUDENTS MSc (Research) Program 2910 PhD Program 1870 * BSc (Nanotechnology) students are included in the totals
2
4
4
4
6
8
11
45
55
69
86
88
78
88
94 / annual report
Honours Enrolments The following Honours students were enrolled during all or part of the 2013 reporting period. Student
Supervisor
James Kieran Balshaw
A/Prof. Pall Thordarson
Jeffrey James Black
Dr Leigh Aldous
Hubert Chan
Dr Chuan Zhao
Christopher Barnett
A/Prof. Marcus Cole
Vera Diachenko
Professor Barbara Messerle
Therese Hadjia
Dr Leigh Aldous
William Hart
Dr Jason Harper
Edward Jiang
Dr William Alex Donald
Nicholas Konstandaras
Dr Jason Harper
Benjamin Boon Yuen Lau
Dr Leigh Aldous
Aggie Lawer
Dr Luke Hunter
Bernadete Cencia Lay
Dr Leigh Aldous
Anthony Richard Leverett
A/Prof. Marcus Cole
Ban Lieu
Professor Naresh Kumar
Tanya Tan
Professor Les Field
Siyao Wang
A/Prof. John Stride
Jonathan Wojciechowski
A/Prof. Pall Thordarson
Chin Ken Wong
A/Prof. Pall Thordarson
Daryl Qi Jin Yap
Dr Luke Hunter
Yuqi Zhang
A/Prof. Shelli McAlpine
Medicinal Chemistry Honours Students: Madhuka Abeysekera
A/Prof. John Stride
Catherine Au
Dr Luke Hunter
Yilin Chen
Professor Naresh Kumar
Rebecca Jayanthakumar
A/Prof. John Stride
Yun Cheuk Leung
Professor Naresh Kumar
Jacqueline Liu
A/Prof. Jonathan Morris
Michelle Nguyen
Professor Naresh Kumar & Dr Angela Finch
Vincent Tan
Scientia Professor Justin Gooding
Elysha Taylor
A/Prof. Jonathan Morris
Ann Teo
Dr Alex William Donald
Oscar Thach
Professor Naresh Kumar
Johny Trinh
Dr Luke Hunter
Matthew Wakeham
Dr Angela Finch
Chenyang Wan
Dr Chuan Zhao
Stephen Wearmouth
A/Prof. Jonathan Morris
Yuqi Zhang
A/Prof. Shelli McAlpine
School / 95
Postgraduate Coursework Enrolments The following postgraduate coursework students were enrolled during all or part of the reporting period for 2013
Graduate Diploma in Chemical Analysis and Laboratory Management (Program 5648) Fiona Cotter
Eiman Alahmadi Thi Nguyet Thu Nguyen Jameel Ali Alqahtani Erin Lin Qiao
Monica Hibberd
Abdullah Awadh Althomali
Tania Jocelyn Tan
Chao Shen
Master of Science and Technology in Chemical Analysis and Laboratory Management (Program 8708 MScTech)
Pankaj Kumar Barai Hsin-Yu Shih Yi Chen Johan Van Den Bosch
Rasha Ali Alasmari
Bruce Gosk
Rozza Kaabi
Yuan Wei
Turki Hamid Alhiji
Robert Hartley
Pei-Chen Kuo
Cheng Long Xiao
Hajar Hmoud Alhwaiti
Chih Hsien Hsiao
Tian Luo
Mancen Zhao
Mohammad Habl Almatin
Xinshang Ji
Zhouyue Lv
Postgraduate Research Enrolments The following postgraduate research students were enrolled during all or part of the reporting period for 2013
Master of Science by Research (Program MSc2910 & MPhil 2475) Candidate
Research Area
Supervisor
Lachlan Carter
Nanoparticle-mediated electrochemical gating: application to electroanalysis
Scientia Prof. Justin Gooding
Genevieve Duche
Supramolecular chemistry & nanomaterials
A/Prof. Pall Thordarson
Mengchen Ge
Ionic Liquids-Based Gas Sensor
Dr Chuan Zhao
Hao Jiang
Synthesis of indole-containing macrocycles
Prof. David Black, Prof. Naresh Kumar
Adrian Pietkiewicz
Synthesizing macrocyclic peptides from the sanguinamide b class
A/Prof Shelli McAlpine
Yuvixza Lizarme Salas
Medicinal Chemistry: towards a treatment for stroke
Dr Luke Hunter
Chao Shen
Supramolecular chemistry
Dr Jonathon Beves
Worawan Tantisantisom
Synthesis of Sanguinamide B derivatives Synthesis of Sanguinamide B derivatives: Structure-Activity Relationship and mechanism of action
A/Prof. Shelli McAlpine
Jonatan Wangsahardja
Flourinated amino acids
Dr Luke Hunter
Chang Long Xiao
Electrochemical energy conversion & storage
Dr Chuan Zhao
Ran Xu
Photochemistry of Organic Reactive Intermediates Monitored with NMR Spectroscopy
Dr Graham Ball
96 / annual report
Doctor of Philosophy, Chemistry (Program 1870) Candidate
Research Area
Supervisor
Moshiul Alam
Isolation of Mo from Uranium/Aluminium target plates at ANSTO
A/Prof. Marcus Cole
Iqbal Ahmed
Conformational Fine-Tuning of Cyclic Peptides
Dr Luke Hunter
Majid Asnavandi
Nanomaterial for electrochemical sensors and energy
Dr Chuan Zhao
Abbas Barfidokht
Electrochemical sensors
Scientia Prof. Justin Gooding
Murat Bingal
Synthesis of novel anti-cancer agents
Prof. David Black & Prof. Naresh Kumar
Nripendra Biswas
Novel Small Molecules for the Modulation of Bacterial Signaling Pathways
Prof. Naresh Kumar
Bradley Butler
Ionic Liquids
Dr Jason Harper
Kai Buys
Stabilisation of heavy group 14 metallohydrides
A/Prof. Marcus Cole
Raju Cheerlavancha
Synthesis of alpha, beta, gamma-trifluoro- delta-amino acids
Dr Luke Hunter
Xin Chen
Nanoparticles for sensing
Scientia Prof. Justin Gooding
Xiaoyu (Jet) Cheng
Silicon luminescent nanoparticles
Scientia Prof. Justin Gooding
Sandra Choy
Understanding Cooperative Catalysis with Bimetallic Rhodium(I) Complexes
Prof. Barbara Messerle
Moinul Haque Choudhury
Nanoparticle modified electrodes
Scientia Prof. Justin Gooding
Kyloon Chuah
Nanoparticle â&#x20AC;&#x201C; nanopore sensors
Scientia Prof. Justin Gooding
Joana Da Rocha
Design of kinase inhibitors
A/Prof. Jonathan Morris
Swahnnyia De Almeida
Development of a Circulating MicroRNA Biosensor for the Detection and Monitoring of Lung Cancer
Scientia Prof. Justin Gooding
Michelle Dunn
Carbenes in Ionic liquids
A/Prof. Marcus Cole & Dr Jason Harper
Dominic Francis
Fluorous Chemistry
Dr Jason Harper, A/Prof. Roger Read
Samantha Furfari
Applications of N-heterocyclic carbenes in inorganic chemistry
A/Prof. Marcus Cole
Christopher Gardner
Innovative utilisation of carbocation reactivity for the synthesis of biologically active flavones and isoflavones
Prof. Naresh Kumar
Mark Gatus
Design of Multimetallic Complexes for C-X Bond Formation
Prof. Barbara Messerle
Stephen George
Ionic liquids
Dr Jason Harper
Joshua Ginges
Immuno-biosensors
Scientia Prof. Justin Gooding
Christian Gunawan
NanomaterialS for electrochemical sensors and energy
Dr Chuan Zhao
Bakul Gupta
Nanoparticle self-assembly
Scientia Prof. Justin Gooding
Mathew Gyton
Ring Expanded NHCs for Asymmetric Catalysis
A/Prof. Marcus Cole
Fei Han
Nanomedicine
Scientia Prof. Justin Gooding
Md Musfizur Hassan
Self assembly & drug delivery
A/Prof. Pall Thordarson
Robert Healey
The Supramolecular Chemistry of Natural Sweeteners
A/Prof. Pall Thordarson
Kam Hong
Synthesis of Novel Biologically Active Scaffolds Based on Flavonoids and Isoflavonoids
Prof. Naresh Kumar
Mokarrom Hossain
Lignin Processing in Ionic Liquid: Electrochemical approaches towards Dissolution and Depolymerisation
Dr Leigh Aldous
Ethan Howe
Supramolecular chemistry and self-assemble
A/Prof. Pall Thordarson
Amirul Islam
Antibacterial research developments
A/Prof. Shelli McAlpine
Scott Jamieson
Self-assembled materials, supramolecular chemistry, application of gels in biomedicine and microscopy in chemistry
A/Prof. Pall Thordarson
Cheng Jiang
Protein resistant electrodes for biosensing
Scientia Prof. Justin Gooding
Sinead Keaveney
Ionic liquids to control reaction outcomes
Dr Jason Harper
Asim Khan
Oxygen reduction reaction in ionic liquids
Dr Chuan Zhao
Parisa Sowti Khiabani
Photonic crystal biosensors
Scientia Prof. Justin Gooding
Rima Khoury
Multi-way models of multi-way interactions between metal ions and oligopeptides
Prof. Brynn Hibbert
Seong Kim
Synthesis of macrocyclic peptides
A/Prof. Shelli McAlpine
Yen Koay
Organic synthesis & methodology
A/Prof. Shelli McAlpine
Alistair Laos
Understanding Quantum Phenomena in Photosynthesis: Moving Toward Synthetic Mimics
A/Prof. Pall Thordarson
School / 97
Thanh Le
Systems of novel peptidomimetics
Prof. Naresh Kumar
Yeng Lee
Organometallic complexes for electrochemical bio-sensors
Prof. Barbara Messerle
Devi Liana
Paper sensors
Scientia Prof. Justin Gooding
Kang Liu
Nanoparticle sensors
Scientia Prof. Justin Gooding
Renecia Lowe
Optimising molecules with biomedical potential using selective fluorination chemistry
Dr Luke Hunter
Xunyu (Rain) Lu
Nanomechanic and nanoparticle based sensors
Dr Chuan Zhao
Yong Lu
Developing nanofabricated surfaces for cell biology and cell based biosensors
Scientia Prof. Justin Gooding
Xun (Luke) Lu
Super-resolution Fluorescence microscopy for Surface Characterisation
Scientia Prof. Justin Gooding
Jeanette Mcconnell
Synthesis and mechanistic evaluation of hsp90 inhibitors as anticancer agents
A/Prof. Shelli McAlpine
Alasdair Mckay
Hybrid complexes and photochemical studies by NMR
A/Prof. Marcus Cole
Alexander Mcskimming
Inorganic chemistry
A/Prof. Stephen Colbran
Alexander Mason
Development of Tools for Synthetic Cell Research
A/Prof. Pall Thordarson
Marcin Mielczarek
New heterocyclic compounds related to flavones
Prof. David Black
Toby Mills
Analysis of micro-organism derived compounds for drug discovery
Dr Alex Donald
Elizabeth Murago
Analytical chemistry of oils
Scienta Prof Justin Gooding
Ashwin Gopalan Nair
Transition Metal Catalysts containing N-Heterocyclic Carbene Pincer ligands
Prof. Barbara Messerle
Ekaterina Nam
Surface-bound Light-activated Redox Enzyme Cascades
A/Prof. Pall Thordarson
Justin Nash
Synthetic Approaches to Rulepidanol and Embellistatin
A/Prof. Jonathan Morris
Thi Diep Nguyen
Exploitation of bacterial transcription initiation as a target for new antimicrobials
Prof. Naresh Kumar
Maryam Pariz
Dual sensing of cells attachment and spreading using electrochemical impedance and optical fluorescence microscopy
Scientia Prof. Justin Gooding
Stephen Parker
Switchable surfaces for cell biology
Scientia Prof. Justin Gooding
Aravind Ramachandran
Electroanalytical chemistry
Scientia Prof. Justin Gooding
Andrew Robinson
Therapeutic peptides and peptide hydrogels for medical application
A/Prof. Pall Thordarson
Sumi Shrestha
Bioinspired reduction catalysis
A/Prof. Steve Colbran
Bryan Suryanto
The development of metal-free carbon nanostructures based electrocatalysts for electrochemical energy conversion
Dr Chuan Zhao
Safura Taufik
Development of an Electrochemical Biosensor based on Gold Nanoparticles for the Detection of Biomarkers
Scientia Prof. Justin Gooding
Aditi Taunk
Synthesis of novel heterocyclic pyslems
Prof. Naresh Kumar
Roya Tavallaie
Towards the biomedical applications of gold coated magnetic nanoparticles: Detection of serum circulating MicroRNAs as cancer markers
Scientia Prof. Justin Gooding
Veronica Tecchio
The Development of Pyrrolopyrimidines as Kinase Inhibitors
A/Prof. Jonathan Morris
Hamish Toop
Development of Synthetic Protocols for Application in the Syntheses of Biologically Interesting Molecules
A/Prof. Jonathan Morris
Andrey Tregubov
Rh (I) complexes anchored on carbon supports - recyclable catalysts
Prof. Barbara Messerle
Warren Truong
Interactions of Self-Assembling Gels with Living Systems
A/Prof. Pall Thordarson
Daniel Twycross
Bulky n-heterocyclic carbenes and their utility in catalysis
A/Prof. Marcus Cole
Hendra Wahyudi
Development of Macrocyclic peptides into Lead structures
A/Prof. Shelli McAlpine
Yao Wang
Hsp90/Hsp70 dual inhibition study in cancer treatment and discovery of novel Hsp70 inhibitors
A/Prof. Shelli McAlpine
Alexander Weremfo
Effectiveness of Roughened Platinum Microelectrodes in Neural Stimulation
Dr Chuan Zhao
Chin Min Wong
Organometallics and Catalysis
Prof. Barbara Messerle Messerle
Ying Yang
Light Controlled Electrochemistry on Silicon Electrodes: Application to the Capture and Release of Single Cells
Scientia Prof. Justin Gooding
Vineeth Yasaparundi
Molecular approaches to third generation photovoltaics
Prof. Tim Schmidt
Fatemeh Mirnajafi Zadeh
Investigations into quantum dots
A/Prof. John Stride
98 / annual report
Conference Presentations 2013 – Students
7th Australian Organometallics Discussion Group Meeting (OZOM7), Victoria University, Wellington New Zealand, 13-16 January 2013. Hsiu Lin Li Iron and Ruthenium Phenyl- and Methyl-substituted Hydrazine, Hydrazide and Diazene Complexes. Matthew Gyton Studies of the Metal Organoamide Chemistry of a Sterically Demanding 1,3-Triazenide
Australian and New Zealand Society for Mass Spectrometry, Melbourne, February. M. Leeming Mobile proton triggered radical fragmentation of nitroarginine containing peptides. K.K. Hoi Dissecting the insect detoxification machinery with twin ion metabolite extraction (TIME) mass spectrometry.
12th Topical Meeting of the International Society of Electrochemistry, Bochum, Germany, 17-21 March 2013. E. Murago, R. Amal, J. Gooding, D.B. Hibbert. Au@Fe3O4 Nano-Electrodes: Their Electroanalytical Performance as ‘Dispersible Electrodes’ and their use as Sensors, Bioelectrochemistry 2013
23rd Reactive Organometallics Symposium (ROMS23), Australian National University, Canberra, 21st June 2013 Chin Min Wong, Khuong Q. Vuong, Andrey A. Tregubov and Barbara A. Messerle. Towards the Synthesis of Efficient and Recyclable Catalysts
4th International Conference on NanoMedicine, Sydney 1-3 July 2013. S.B. Lowe, J.A.G. Dick, J.E. Ghadiali, V. Tan, A.H. Soeriyadi, B.E. Cohen, M.M. Stevens, J.J. Gooding. Oral Prize winner Nanoparticle-Peptide Conjugates as Multiplexing Enzyme-Responsive Systems for Evaluation of Enzyme Activity and Drug Delivery B. Gupta, P.J. Reece, K. Gaus, J.J. Gooding. Porous Silicon microsensors for sensing protease activity in vivo Y. Zhu, A.H. Soeriyadi, P.J. Reece, K. Gaus, J.J. Gooding. Micropatterned Porous Silicon Photonic Crystal Towards Single Cell Activity Monitoring A.H. Soeriyadi, X. Chen, B. Gupta, J.J. Gooding. Enzymatic responsive porous material-polymer construct for biomedical application
RACI Biomolecular Division Conference “In the Bush”, Leura NSW, 14-17 July Hamish Toop. Examining AAL(S) as a New Lead for the Treatment of Leukaemia
24th International Congress on Heterocyclic Chemistry, Shanghai, 8-13 September 2013. Murat Bingül Synthesis of novel heterocyclic compounds that enhance the anti-cancer activity of SAHA
School / 99
International Symposium on Surface and Interface of Biomaterials, Rome, 24-28 September 2013. Leong A, Cole N, Willcox M, Kumar N. An antimicrobial and biocompatible peptide surface coating
Interact 2013: Profiling and stimulating interdisciplinary research, Melbourne, October M. Leeming Small needles, big haystacks, and a smart comb: Integrating network theory and mass spectrometry to improve pharmaceutical development.
24th Reactive Organometallics Symposium, Sydney, 8th November 2013. Ran Xu NMR studies of (HEB)W(CO)2(methylcyclopentane) complexes Vera Diachenko, Barbara. A. Messerle. Bimetallic Rh(I) Complexes as Catalysts for the Dihydroalkoxylation, Hydrocarboxylation and Hydrosilylation of Alkynes Andrey A. Tregubov, Rasmus J. Linser, Khuong Q. Vuong, Aditiya Rawal, John Gehman and Barbara A. Messerle. Solid-state NMR structure determination and distance measurements in Ir(I) complexes with phosphinepyrazolyl ligand Hsiu Lin Li Nitrogen Fixation on Iron Phosphine Complexes
ISE Satellite Student Regional Symposium on Electrochemistry, Melbourne, November 2013. Xunyu Lu, Chuan Zhao. High Performance Co-Based Composite Catalysts for Sustained Electrochemical Oxygen Evolution Asim Khan, Xunyu Lu, Leigh Aldous, Chuan Zhao. The oxygen reduction reaction in room temperature protic ionic liquids
19th Australian/New Zealand Electrochemistry Symposium (19ANZES), Melbourne, 25-26 November 2013. M.H. Choudhury, S. Ciampi, X. Lu, C. Zhao, J.J. Gooding. Cysteine-Modified Sintered Gold Electrodes on Paper as a Low Cost Electrochemical Sensor D. Liana, B. Raguse, L. Wieczorek, G.R. Baxter, K. Chuah, J.J. Gooding, E. Chow. Cysteine-Modified Sintered Gold Electrodes on Paper as a Low Cost Electrochemical Sensor R. Tavallaie, N.A. Darwish, D.B. Hibbert, J.J. Gooding. An Electrochemical Biosensor for Selective Detection of MicroRNA Janjira Panchompoo. Carbon Black Nanoparticles: Surface Modification, Characterisation and Potential Applications
12th International Conference on Frontiers of Polymers and Advanced Materials, Auckland, New Zealand, 8-14 Dec 2013. A. Soeriyadi, B. Gupta, P.J. Reece, J.J. Gooding.
Medicinal Chemistry Symposium, UNSW Australia, November 2013. Kutty S, Barraud N, Pham A, Black D, Kumar N. Synthesis of nitric oxide donors based on fimbrolides as antimicrobials Ahmed, M. I. Ring expansion as a general method for improving peptide cyclisation
Clicking” Polymer onto Porous Silicon Photonic Crystal Structure: Towards Single Cells Biosensor
100 / annual report
34th Annual One Day Symposium, Royal Australian Chemical Institute New South Wales Organic Group, Australian National University, ACT, Australia, 4th December 2013. Michelle H. Dunn, Nicholas Konstandaras, Marcus L. Cole and Jason B. Harper. “Structure effects on the acidity of heterocyclic carbon acids: Towards correlations with catalytic efficiency” Hamish Toop. Total Synthesis of Dioncophylline E and Other Related Naphthylisoquinoline Alkaloids
RACI Inorganic Chemistry Divisional Conference (IC’13), Brisbane 8th-12th December 2013. Michael J. Page, Giulia Mancano and Barbara A. Messerle. Dynamic Coordination of NCN Pincer Ligands to Rh(I) and Ir(I) and the Consequence for Catalysis. Chin Min Wong,1 Andrey A. Tregubov,1 Khuong Q. Vuong1 and Barbara A. Messerle1. Towards the Synthesis of Efficient and Recyclable Catalysts
School / 101
Conference Posters 2013
7th Australasian Organometallics Discussion Meeting (OZOM 7), Wellington, New Zealand January 13-16, 2013 Michael J. Page, Barbara A. Messerle. Bimetallic Carboxamide Complexes: Apparent Cooperativity from an Uncooperative Catalyst. M. R. D. Gatus, B. A. Messerle, K. Q. Vuong. Homo and Heterobimetallic Complexes for Tandem One-Pot Reactions. Alison M. Magill, Peter M. Jurd, Leslie D. Field. Activation of CO2 and CS2 by Cyclometallated Complexes of Ru(II) and Fe(II) Martin, TA; Furfari, SK; McKay, AI; Cole, ML. Heavyweight Hydrides. Buys, KN; Gyton, MR; Dunn, MH; Harper, JB; Cole, ML. An Ionic Liquid Derived Carbene. Cole, ML; Twycross, D; Martin, TA; Konstandaras, N; McKay, AI. Flexible N-Heterocyclic Carbenes: Superior Ligands for Suzuki Cross Coupling.
3 International Conference on Multifunctional, Hybrid and Nanomaterials, 3-7th March 2013, Sorrento, Italy rd
Ethan N. W. Howe, Roger Bishop, Pall Thordarson. Synthetic molecular receptors towards mimicry of allosteric enzymes and haem proteins
Ekaterina Nam, Daniel C. Goldstein, Pall Thordarson. Surface-bound Light-activated Redox Enzyme Cascades
Lowy Cancer Symposium, UNSW Australia, 15-17 May 2013 Kumar N, Yee E, Pasquier E.
Synthesis of novel isoflavenepropranolol hybrids as antitumor agents. Hamish Toop. Examining AAL(S) as a New Lead for the Treatment of Leukaemia
43rd National Organic Symposium, Seattle USA, 23 – 27 June Hamish Toop. Total Synthesis of Dioncophylline E and Other Related Naphthylisoquinoline Alkaloids
20th EuCheMS Conference on Organometallic Chemistry St Andrews, UK, 30th June – 4th July 2013 M. R. D. Gatus1, K. Q. Vuong1, and B. A. Messerle1.
A. Tregubov, K. Q. Vuong, E. Luais, J. J. Gooding and B. A. Messerle. Rh(I) complexes of N,N and N,P ligands covalently bound to carbon surfaces: Recyclable Hydroamination Catalysts.
4th International Conference on NanoMedicine, Sydney 1-3 July 2013 R. Tavallaie, N.A. Darwish, D.B. Hibbert, J.J. Gooding. An E-DNA Based Electrochemical Biosensor for Detection of MicroRNA miR-21. Poster Prize Winner
The Southern Highlands Conference on Heterocyclic Chemistry, Bowral, 25-27 August 2013 Murat B, Cheung B, Black D, Kumar N. Synthesis of novel heterocyclic compounds that enhance the anti-cancer activity of SAHA Thanh L, Black D, Kumar N A concise synthesis of 1,4-benzodiazepin-2-ones from N- aminoacylisatins
Reactivity of Rh(I) Bimetallic Complexes & The Synthesis of Heterobimetallic Complexes Containing Au(I)/Rh(I) & Rh(I)/Ir(I)
RACI Natural Products Chemistry Group Annual OneDay Symposium 2013, UNSW Australia, September 2013
S. W. S. Choy and B. A. Messerle.
Kutty S, Barraud N, Pham A, Black D, Kumar N.
Flat Rh(I) complexes for catalysed hydroalkoxylation and hydroamination reactions. G. Mancano, M. J. Page, B. A. Messerle. Variable NCN Ligand Coordination in Rh(I) and Ir(I) Catalysts.
Synthesis of nitric oxide donors based on fimbrolides as antimicrobials. Ho K, Willcox M, Kumar N Immobilization of antibacterial dihydropyrrol-2-ones for the prevention of bacterial infections
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Biswas N, Kutty S, Barraud N, Black D, Kumar N Indole-based novel small molecules for the modulation of bacterial signalling pathways Murat B, Cheung B, Marshall G, Black D, Kumar N Identification of novel heterocyclic molecules that enhance the anticancer effects of HDAC inhibitors
3rd European Conference on Cyclodextrin (ECC-2013), Antalya, Turkey, 2-4th October 2013 Robert Healey, Shiva Prasad, Vijava Rajendram, Pall Thordarson. Cyclodextrin Interactions with G-Protein Coupled Receptor Peptide Mimic
Alexander Weremfo, Paul Carter, D. Brynn Hibbert, Chuan Zhao In vitro Characterization of Electrochemically Roughened Platinum Microelectrode for Neural Stimulation Christian Gunawan, Pall Thordarson, Chuan Zhao Scanning electrochemical microscopy of switchable redox enzyme cascades
3rd International Conference on Cucurbiturils (ICCB-3), UNSW Canberra, ACT, Australia, 18-20 November, 2013 Zaki Krag Nielsen, Michael Pittelkow, Pall Thordarson. Dynamic combinatorial & bioconjugate chemistry – towards protein stoppered rotaxanes
Hamish Toop. Total Synthesis of Dioncophylline E and Other Related Naphthylisoquinoline Alkaloids Poster Prize Winner
RACI NSW natural Products Symposium, Sydney, 4th October 2013 Cheerlavancha, R. Synthesis of α,β,γ-trifluoro-δamino acids.
ISE Satellite Student Regional Symposium on Electrochemistry, Melbourne, November 2013. Changlong Xiao, Alexander Weremfo, Alan Bond, Chuan Zhao, Electrochemical determination of water in non-aqueous media Bryan Suryanto, Xunyu Lu, Chuan Zhao Layer-by-layer Assembly of Transparent Graphene-based Electrodes for Water Splitting Mengchen Ge, Christian Gunawan, Chuan Zhao The electrochemical stability of alkanethiolate self-assembled monolayers in ionic liquids
Chen Y, Iskander G, Kutty, S, Kumar N, Pasquier, E Synthesis of isoflavene Mannich bases as anticancer agents Biswas N, Kutty S, Barraud N, Black D, Kumar N Indole-based novel small molecules for the modulation of bacterial signalling pathways Trinh, J.; Au, C.; Hu, X.-G. Modifying Peptide Conformation: Effects on Synthetic Efficiency and Biological Activity Salas, Y. L. Towards a treatment for stroke: Synthesis of analogues of dictyoquinazol A Lowe, R. Fluorinated GHB analogues: GABA receptor studies and improving therapeutic drugs
37th Annual Conference of the Australian Society for Biophysics (ABS 2013), RMIT campus, Melbourne, VIC, Australia, 24-27th November 2013
Cheerlavancha, R.
Robert Healey, Shiva Prasad, Vijava Rajendram, Pall Thordarson.
19th Australian/New Zealand Electrochemistry Symposium (19ANZES), Melbourne, 25-26 November 2013
Interactions of G-protein Coupled Receptor Agonist Mimic with Cyclodextrins Alistair Laos, Pall Thordarson, Paul Curmi. Biomimetic Light Harvester; An Adduct of a Quantum Coherent Protein – Phycocerthrin 545 Ekaterina Nam, Pall Thordarson. Light-activated Redox Enzyme Cascade Alex Mason, David Hvasanov, Pall Thordarson. Development of a LightControlled Polymersome Nanoreactor
Medicinal Chemistry Symposium, UNSW Australia, 25th November 2013 Thach O, Kumar N. Novel inhibitors of bacterial transcription initiation complex formation.
Synthesis of α,β,γ-trifluoro-δamino acids (Equal 1st prize winner)
Y. Yang, S. Ciampi, M. Choudhury, J.J. Gooding. Electrochemical Characteristics of Anthraquinone-containing Selfassemble Monolayers on Silicon Electrode. L. Carter, J.J. Gooding Utilising Nanoparticle-Mediated Electrochemical Gating to Prepare a Novel Sensing Platform A. Barfidokht, S. Ciampi, E. Luais, N. Darwish, J.J. Gooding Distance-Dependant Electron Transfer at Passivated Electrodes Decorated by Gold Nanoparticles C. Jiang, X. Chen, N. Darwish, S. Parker, A. Soeriyadi, J.J. Gooding Mixtures of Functionalized Aromatic Groups Generated From Diazonium Chemistry on Indium Tin Oxide Electrode Surfaces
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The Messerle Research Group
S. Taufik, J.J. Gooding Formation of a Stable Sensing Interface based on Aryl Diazonium Salt and Gold Nanoparticle Modified on Gold Electrode
ISE Satellite Student Regional Symposium on Electrochemistry, Melbourne, Australia, 25th November 2013 Md. Mokarrom Hossain. Electrochemistry of Chloride in Ambient Room Temperature Ionic Liquids: Formation of Oxychloride Species.
34th Annual One Day Symposium, Royal Australian Chemical Institute New South Wales Organic Group, Australian National University, ACT, Australia, 4th December 2013 Christopher D. Barnett, Marcus L. Cole and Jason B. Harper Investigating the stereoelectronic properties of normal and abnormal NHCs and the effect on organocatalysis
Eden E. L. Tanner, Hon Man Yau, Rebecca R. Hawker, Anna K. Croft and Jason B. Harper Does the cation really matter? The effect of modifying an ionic liquid cation on an SN2 process Nicholas Konstandaras, Marcus L. Cole and Jason B. Harper Correlating the structure and properties of thiazolium salts with the catalytic efficacy of the corresponding carbenes Sinead T. Keaveney, Ronald S. Haines and Jason B. Harper Understanding and prediction organic reaction outcomes in ionic liquids Lowe, R. Fluorinated GHB analogues: GABA receptor studies and improving therapeutic drugs. Ahmed, M. I. Ring expansion as a general method for improving peptide cyclisation Cheerlavancha, R. Synthesis of α,β,γ-trifluoro-δamino acids
Trinh, J.; Au, C.; Hu, X.-G. Modifying Peptide Conformation: Effects on Synthetic Efficiency and Biological Activity
RACI Inorganic Chemistry Divisional Conference (IC’13), Brisbane 8th-12th December 2013 Mark R. D. Gatus1, Khuong Q. Vuong1 and Barbara A. Messerle1 Reactivity of Rh(I) Bimetallic Complexes & The Synthesis of Heterobimetallic Complexes Containing Au(I)/Rh(I) & Rh(I)/Ir(I),. Ashwin Gopalan Nair, Dr Michael J Page, Ru Complexes of NHC based Pincer complexes in catalysis Cole, ML; Gyton, MR: Chelating Sterically Demanding Amide Complexes of Rare Earths
schoolvisiting committee sectionseven head of school report academic staff research teaching and learning students school school visiting committee retirements obituaries
School Visiting Committee 2013 sectionseven
07 The Committee has representatives from our key stakeholder organisations – industry, government, schools and government research institutes. The terms of reference for the committee are as follows: To appraise the School programs in light of the needs of the School stakeholders (industry, government, schools and research institutions). To provide advice about the direction that the School should take to best enhance future interactions with our stakeholders. To provide advice about the changing needs of industry, research and government organisations to best prepare the School’s graduates for future opportunities.
To receive and discuss the School of Chemistry’s Annual Report. To aid the development of the School in any other way possible. The committee meeting with the School was very successful. This was the final meeting for this committee as their three-year tenure came to an end. The School will be inviting a new committee to take part in School activities in 2014.
External Representatives from Industry, Government and Education Dr Attila Tottszer (Chair)
Business & Development Manager, Advanced Analytical Laboratories
Dr Christopher Armstrong
Associate Director, Science, CRC Liaison Officer, Ministry for Science and Medical Research
Dr Greg Simpson
Acting Director, CSIRO Niche manufacturing Flagship
Dr Herma Buttner
Senior Advisor, Research Management and Science Policy – ANSTO
Mr Roger Leigh
Senior Project Manager, Cochlear
Mr Gary Molloy
Science Teacher, St Aloysius College
Mr Jeff Stanger
Head Science Teacher, St George Girls High School
Ex Officio Members Professor Barbara Messerle
Head, School of Chemistry
Scientia Professor Justin Gooding
Deputy Head, School of Chemistry
A/Prof. John Stride
Director of Research, School of Chemistry
Dr Gavin Edwards
Director of Teaching, School of Chemistry
retirements sectioneight head of school report academic staff research teaching and learning students school school visiting committee retirements obituaries
Retirements sectioneight
Chemistry, the Royal Australian Chemical Institute and the Royal Society of New South Wales as well as receiving RACI Analytical Medal in 1999 and the 2007 RACI Ollé Prize for his book Quality Assurance in the Analytical Chemistry Laboratory (OUP, New York, 2007). Brynn’s contributions to the School and Chemistry go far beyond his research. He is still a member of the Chemical Analysis Advisory Committee of the National Association of Testing Authorities (NATA), 2000 – 2013 and of the Reference Materials Advisory Committee of
Professor D. Brynn Hibbert In mid 2012 Professor Brynn Hibbert announced his retirement in February 2013. It was a sad day for the School when Brynn closed his office door for the last time as a paid employee of UNSW. Certainly Brynn’s normally jovial demeanour however did not seem affected. Brynn had been a member of the School since 1987 when he joined the School as Professor of Analytical Chemistry at the tender age of 36. At UNSW he served as Head of School between 1993 and 1996. He started his academic career in London with a PhD from the University of London followed by a research assistant position at London City University. Lectureship positions at Bedford College, London University and then the merged Royal Holloway and Bedford New College followed before coming to UNSW. During his years at UNSW he made outstanding research contributions in a number of fields including electrochemistry, sensors, fractal chemistry, chemometrics and metrology, surface chemistry and artificial intelligence in chemistry. The results of these endeavours were many PhD graduates and around 200 research papers. Some of these papers are the most highly cited papers in the history of the School of Chemistry. His contribution to chemistry has been well recognised by a number of external bodies with the award of fellowships from the Royal Society of
NATA, 2000 - 2013. As of 2014 he will be President of the Analytical Chemistry Division of the International Union of Pure and Applied Chemistry (IUPAC), 2014 – 2015, and he is the Vice-President of the Royal Society of New South Wales, 2011 – present. He has also actively mentored a number of junior academics in the School of Chemistry, a role that has made a major contribution to their success. Brynn has always been a very passionate and innovative teacher. Part of this innovation has included actively incorporating new technologies to our teaching programs including winning funding to establish electronic notebook technology at UNSW and employing Twitter in teaching (the subject of one of his more recent papers). It is because the School wanted to recognise his teaching contributions as well as his research and administrative contributions that Brynn will be awarded the 2014 Mellor Medal and Lecture. Fortunately Brynn has remained active in the School since retiring. He is still heavily involved in his court based consultancy work, which brings a bevy of entertaining tales, he is guiding his remaining PhD students to completion and is always available to provide advice on research questions and other matters. Long may this continue!
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Dr Nicholas Kenneth Roberts On January 18 2013 Nick Roberts surprised all in the School with an e-mail announcing that Saturday 20 July would mark a new beginning for him as a man of leisure: 19 July 2013 would be Nick’s last day as a staff member in the School of Chemistry. Nick’s academic path was a neat contrast to his early farm days: he started at the University of Western Australia (PhD with Bruce Wild), detoured to Toronto (with Bryce Bosnich) and then the ANU (with Martin Bennett) before signing on as a lecturer in inorganic chemistry in the School of Chemistry at UNSW in 1984. Nick’s research interests centred around organometallic complexes and phosphine ligands, with a dalliance applying his extensive knowledge of inorganic chemistry to surface science in collaboration with Robert Lamb in later years. Nick’s major passion was teaching and passing on his wealth of knowledge, experience and enthusiasm to the next generation. His contributions extended far beyond the lecture rooms and undergraduate laboratories to outreach events such as the RACI titration competitions, and Nick’s reputation as a Chief Magician in the Open Day Chemistry Magic Shows at is the stuff of legend.
From 2004 until his retirement Nick was the Coordinator of First Year Studies in the School of Chemistry, and he oversaw several major changes including the transition from the old Heffron labs to the Chemistry labs in our new building (in more recent years assisted here by Dr Ron Haines). One of the hallmarks of Nick’s tenure in this challenging position was his commitment to individual pastoral care whenever students needed help. It wasn’t uncommon to find queues of students outside Nick’s door, waiting for help!
In writing his 18 January e-mail Nick said “when the time comes to depart, I think the main regret will be missing the great people in Chemistry….” To Nick we say: that works both ways!
On behalf of the School of Chemistry: our heartfelt thanks for many years of outstanding work, and may you both have a long, happy and relaxing retirement!
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obituaries sectionnine head of school report academic staff research teaching and learning students school school visiting committee retirements obituaries
Obituaries sectionnine
09 It was with great sadness that we farewelled our former friend and colleague Juan Araya in 2013.
Juan Araya: 21st December 1943 â&#x20AC;&#x201C; 1st February 2013 Juan commenced employment with the School of Chemistry on the 5th July 1974 as a Grade 1 Technical Officer (Organic) and progressed to the position of Senior Technical Officer. After the restructure of the School Juan was appointed as Manager â&#x20AC;&#x201C; Technical Support Services in 2002. Juan accepted voluntary redundancy in 2005 and enjoyed his retirement with his family whilst also helping his community.
Produced by the School of Chemistry, UNSW Australia UNSW SydNey NSW 2052 AUStrAliA T +61 2 9385 4683 F + 61 2 9662 1697 E chemistry@unsw.edu.au W www.chem.unsw.edu.au rePort editor Jodee Anning, School of Chemistry UNSW PhotogrAPhy lmd, gasbag Studios, Svetislav Videnovik, Steve Preece and School of Chemistry deSigN melinda Jenner, P3 design Studio PriNtiNg Fuji Xerox Copyright Š 2014 UNSW School of Chemistry All information produced in the School of Chemistry Annual Report, was correct at time of printing. UNSW reserves the right to change and update any details contained within this book. CriCoS ProVider Code 00098g