GRASP Newsletter: Vol 4.2

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GRASP

Volume 4 | Issue 2 October 2020

Issue 1 | May 2017

A communication with government on UP’s collaboration with government, government entities, foreign missions and international, inter-governmental organisations

UP contributes to the fight against The

COVID-19 pandemic has affected every corner of the world – be it through infections or associated regulations. In the fight against both the disease and its societal consequences, the University of Pretoria (UP) has taken up the banner to support the country and the continent through this troubling time. Not only are research efforts being undertaken by faculties across the University, but practical efforts to support government on all levels are also visible. UP has far-reaching expertise in a range of areas, and this pandemic has strengthened its collaborative efforts, not only through interdisciplinary research, but also across borders, universities and other organisations. According to the Dean of the University’s Faculty of Health Sciences, Prof Tiaan de Jager, if these collaborative efforts are sustained post-COVID-19, research will be pushed to a new level. Clinical trials and testing UP actively participates in global efforts to eradicate the threat of COVID-19. Its Faculty of Health Sciences forms part of a multi-centre clinical trial study for Africa by the World Health Organisation (WHO), in which various antiviral compounds are investigated. The objective is to provide reliable estimates of the effects of antiviral treatments and chloroquine or hydroxychloroquine on in-hospital mortality. The Faculty has also partnered with the South African Medical Research Council in a study on various rapid testing methods. In addition to these large-scale projects, the Division of Infectious Diseases in the University’s Department of Internal Medicine is leading a study in collaboration with Leicester University (England) to investigate testing for COVID-19 by wearing a face mask for 30 minutes. A COVID-19 mask was developed for this, and other respiratory pathogens can also be identified.

Support for local government As an anchor institution, UP cannot merely contribute to the fight against COVID-19 on a theoretical level. The University is therefore working on projects to support local government, particularly health departments, at grassroots level. UP’s Department of Medical Virology has established a fully functional and accredited testing facility with the National Health Laboratory Services. It provides polymerase chain reaction (PCR) testing and services at the Tshwane District Hospital and Steve Biko Academic Hospital, as well as other healthcare centres in Tshwane, Limpopo and Mpumalanga. Systems protocols have also been put in place in collaboration with the Gauteng Department of Health to screen, manage and treat COVID-19 patients, particularly at the Tshwane District Hospital, Steve Biko Academic Hospital and Kalafong Hospital. Protocols include incubation, clinical care and severity scores, as well as psychosocial support for healthcare workers and patients. In the realm of community health, the University has established the UP Tshwane COVID-19 Care Helpline, which is serviced by doctors and registrars from UP and focuses on people living in the Tshwane district. The Helpline provides guidance to referral testing centres, information on COVID-19 and guidance on self-care. The University has also deployed senior medical students to Tshwane District Hospital and Steve Biko Academic Hospital to support doctors with various COVID-19-related projects, such as the establishment of an online platform for COVID-19-related research publications. In addition, the Faculty of Health Sciences is developing educational material on preventative measures.

UP is undertaking projects at grassroots level to support the fight against COVID-19. In disruptive situations such as this, the exploitation of technology that is currently available is paramount to effective response efforts. In this regard, researchers from the University’s Department of Statistics are engaged in a collaborative project in which multiple evidence-based COVID-19 research projects are coordinated. These include a heat map retrieval of the spread of COVID-19 in South Africa since lockdown using spatial analysis, a probabilistic COVID-19 screening model, modelling the 14-day infection rate of COVID-19, using a synergetic web-based dashboard to track COVID-19 demographic information, and providing an exploratory view of the association between observed weather patterns and COVID-19 infection rates. UP has also developed an application for Steve Biko cluster healthcare workers to track COVID-19-related symptoms daily, and to refer patients for testing if required. In the fight against the pandemic, one of the most pressing concerns is the provision of personal protective equipment (PPE) for health workers. In this regard, the University’s Faculty of Health Sciences was involved in the 3D-printing of 10 000 face shields for the Gauteng Department of Health. Continued on page 2

UP research for COVID-19 edition

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GRASP Newsletter: Vol 4.2 by University of Pretoria - Issuu