University of Mississippi, School of Pharmacy, Graduate Programs for Pharmaceutical Sciences

G R A D U AT E O P P O RT U N I T I E S

Pharmaceutical Sciences

THE UNIVERSITY OF MISSISSIPPI SCHOOL OF PHARMACY PHARMACEUTICAL SCIENCES 1

Why? Have you ever wondered

• How medicines are developed and/or discovered?

• How plants and microbes provide leads in the drug discovery process?

• How medicines are synthesized or manufactured in the pharmaceutical companies?

• How the value of medicines or pharmacy services is determined?

• How to make compounds used in the drug discovery process?

• How to improve the delivery of medicines and pharmacy services in a health care system?

• How safety and efficacy of medicines are tested?

• How adverse impacts in the environment impact human health?

• How dose, dosage form and dosing frequency for medicines are determined?

Do you wish you could • Develop new therapies or improve currently available options?

• Improve and analyze treatment outcomes?

• Come up with new medicines?

• Price medicines?

If you answered “Yes” to any of the above, you should consider a career in pharmaceutical sciences as a pharmaceutical scientist.

Why? Why? INNOVATION & ENTREPRENEURSHIP

63% of new drugs approved by the FDA in 2018 were initially developed by smaller biopharma companies. – HBM Partners 2 UM SCHOOL OF PHARMACY

A pharmaceutical scientist possesses a graduate degree — Master of Science in pharmaceutical sciences or the Doctor of Philosophy degree, which is the terminal degree (highest degree awarded by the university) — unlike a pharmacist, who goes through the professional pharmacy program to receive a Doctor of Pharmacy (Pharm.D.) degree.

The pharmaceutical scientist plays a part in one or more aspects of the development of new medicines and therapies, whereas a pharmacist works on intervention strategies and methods, working with existing medicines.

The pharmaceutical sciences is a confluence of multiple disciplines such as chemistry, biology, molecular biology, toxicology, mathematics, engineering, computation, operations management, marketing, finance and regulatory.

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Introduction Introduction

The University of Mississippi School of Pharmacy offers heofUniversity Mississippi School the Master Science in of Pharmaceutical Sciences of Pharmacy offers the Master of and Doctor of Philosophy in Pharmaceutical Pharmaceutical Sciences.Science Three ofinthe school’s four Sciences and Doctor of Philosophy in Pharmaceutical academic departments (BioMolecular Sciences, Sciences. Three of the school’s four Pharmaceutics and Drug Delivery, and Pharmacy academic departments (BioMolecular Administration) offer these degree programs.Emphases Sciences, Pharmaceutics and Drug include environmental toxicology, Delivery, and Pharmacy Administration) medicinal chemistry, pharmacognosy, offer these degree pharmaceutics, programs.Emphases pharmacology, pharmacy administration include environmental toxicology, medicinal and industrialchemistry, pharmacy. pharmaceutics,

pharmacognosy, pharmacology, pharmacy administration and industrial pharmacy.

All of these programs offer opportunities to study with nationally and internationally recognized research scientists. The programs prepare students for professional pharmacy positions, teaching and research positions in academia, or administrative and research positions in the pharmaceutical, chemical, agrochemical, food and health care industries and government agencies. Our diverse graduate community includes outstanding faculty and students from around the globe, and their cutting-edge research and scholarship reflect tremendous vitality, impact and significance.

Intro Learn more at https://pharmacy.olemiss.edu/ graduateprograms/

PHARMACEUTICAL SCIENCES 3

Job

Career Expectations

Career Compensation

70,619 -150,369

$

Salary Range for an Assistant Professor for Calendar-Year Appointment – American Association of Colleges

of Pharmacy (AACP) 2019-20 Profile of Pharmacy Faculty

106,900

$

Average Base Starting Salary for Pharmaceutical Scientists in the Private Industry – American Association of Pharmaceutical Scientists 2019 Salary Survey

125,000-150,000

$

Median Base Salary for Professionals working in Health Economics and Outcomes Research (HEOR) and Market Access fields – 2017 HEOR & Market Access Global Salary Survey, HealthEconomics.com

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Areas of Employment • • • • • • • • •

Academia Biotechnology Consulting Government/Regulatory agencies such as the Food and Drug Administration Health care organizations Health insurance companies National laboratories such as the National Institutes of Health Pharmaceutical industry Science writing & communication

In what fields do M.S. or Ph.D. graduates work?

• • • • • • • • • • • • •

Analysis and pharmaceutical quality Biotechnology Clinical pharmacology and translational research Drug design and discovery Formulation design, development, and manufacturing Health economics and outcomes research (HEOR) Pharmacoengineering Pharmacoepidemiology Pharmacokinetics, pharmacogenetics, pharmacodynamics and drug metabolism Physical pharmacy and biopharmaceutics Regulatory sciences Social and behavioral pharmacy Toxicology

The University of Mississippi & School of Pharmacy The UniversityINof1848 Mississippi Timeline FOUNDED FOUNDED IN 1848 RANKED IN THE

Mississippi’s Flagship University

TOP 100

R1 CARNEGIE

OF PUBLIC UNIVERSITIES ACROSS THE NATION

by

U.S. News & World Report

UNIVERSITY

NAMED A

FALL 2019-20 FALL 2019-20 19,000 PLUS BEST VALUE UNIVERSITY ENROLLMENT SCHOOL

19K+

Most Beautiful Campus

by U.S. News

by the Princeton Review

& World Report

UNIVERSITY ENROLLMENT

2019-2020 68 Full-time FACULTY

68 42 118 17 2019-20

FOUNDED IN 1908

Mississippi’s oldest pharmacy school and the sole school in the state with a MS/PhD program in Pharmaceutical Sciences

GRADUATE DEGREES

132 Research Grant Proposals Research Grant Submitted for FYProposals Submitted 2019 for FY 2019

132

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RESEARCH CENTERS

AWA RDED 2018-19

Fall 2019-2020 118 graduate Full-time students ENROLLED graduate FACULTY students from more than ENROLLED 17from countries more than countries FALL 2019-20

School of Pharmacy

213 School of Pharmacy PUBLICATIONS of Pharmacy for FY 2019 OurSchool researchers PUBLICATIONS for FY 2019 authored or co-authored 213 Our researchers authored or co-authored 213 peer-reviewed manuscripts

213

peer-reviewed manuscripts

20 Full Professors 21 Associate Professors 25 Assistant Professors 2 Instructors

20 TOP Total Extramural Research Funding Awards for FY 2019 – AACP Total Extramural

20 TOP

Research Funding Awards for FY 2019 – AACP

RANKED IN 17 U.S. PATENT APPLICATIONS Filed BEST GLOBAL UNIVERSITIES

by School of Pharmacy Researchers FOR PHARMACOLOGY U.S. PATENT FY2020 School of Pharmacy & TOXICOLOGY APPLICATIONS – U.S. News & World Report 2019 Filed by School of Pharmacy Researchers

17

FY2020 School of Pharmacy

PHARMACEUTICAL SCIENCES 5

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Fields FieldofofStudy Study

M.S.

Ph.D.

ENVIRONMENTAL TOXICOLOGY Environmental Toxicology includes research and educational activities that seek to identify and resolve problems nvironmental research activities thatresearch seek to related to environmentalToxicology and humanincludes health issues.

Thisand workeducational includes basic and applied identify and resolve problems related to environmental and human health approaches to empower individuals, resource managers, regulators, and communities withissues. the This work includes basic and applied research approaches to empower individuals, knowledge to improve human and environmental health. Research interests of the faculty include quantifying resource managers, regulators, and communities with the knowledge to improve human and environmental contaminants and assessing their impact on environmental and human health.

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environmental health. Research interests of the faculty include quantifying environmental contaminants and assessing their impact on environmental and human health.

Research Areas • Air pollution toxicology • Developmental toxicology and multigenerational fish studies • Ecotoxicological evaluation of chemical mixtures • Effects of pharmaceuticals in the environment • Endocrine disruptors in fish and invertebrates • Environmental monitoring and toxicity bioassays • Impacts of climate change on environmental and community health • Individual- and community-level responses to natural and anthropogenic stressors in the marine environment

External Research Funding • Environmental Protection Agency

• National Science Foundation

• National Aeronautics & Space Administration

• Sea Grant

• National Institutes of Health • National Oceanic and Atmospheric Administration

• U.S. Army Engineer Research and Development Center • U.S. Department of Agriculture • Water Resources Research Institute

FIND OUT MORE: For prerequisites and curriculum, visit https://pharmacy.olemiss.edu/etrp Department of BioMolecular Sciences 662-915-7330 • bmschair@olemiss.edu

PHARMACEUTICAL SCIENCES 7

Field of Study

M.S.

INDUSTRIAL PHARMACY The M.S. in pharmaceutical sciences with an emphasis in industrial pharmacy is a non-thesis track program hetoM.S. in pharmaceutical with an emphasis in pharmacy industrialtopharmacy is a designed provide fundamental andsciences applied knowledge of industrial prepare B.S.-level non-thesis track program designed to provide fundamental and applied knowledge of chemical engineers and scientists (pharmacy, biology and chemistry) for a career in the pharmaceutical industrial pharmacy to prepare B.S.-level chemical engineers and scientists (pharmacy, industry. Students will select a specialty track in their second year of either regulatory sciences biology and chemistry) for a career in the pharmaceutical industry. Students will select a or product development and manufacturing.

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specialty track in their second year of either regulatory sciences or product development and manufacturing.

FIND OUT MORE: For prerequisites and curriculum, visit https://pharmacy.olemiss.edu/pharmaceutics/graduate-programs Department of Pharmaceutics & Drug Delivery 662-915-7341

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PHARMACEUTICAL SCIENCES 9

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Field of Study

M.S.

Ph.D.

MEDICINAL CHEMISTRY

Medicinal Chemistry is an interdisciplinary field, involving not just chemistry but aspects of biological and pharmace Chemistry an interdisciplinary field,identification involving not just chemistry but sciences. Itedicinal is concerned with theisinvention, discovery, design, and preparation aspects of biological and pharmaceutical sciences.

It is concerned with invention, of biologically active compounds, the study of their metabolism, the interpretation of their the mode discovery, design, identification and preparation of biologically active compounds, the of action at the molecular level, and the understanding structure- activity relationships.

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study of their metabolism, the interpretation of their mode of action at the molecular level, and the understanding structure- activity relationships.

Research Areas • Antimicrobial and anti-cancer chemotherapy • CNS-active agents • Cardiovascular drugs • Computer modeling and simulation • Drugs affecting the endocrine system • Fluorine chemistry • New synthetic methods discovery • Toxicological aspects of drug or drug-like molecules in biological systems

External Research Funding • American Association of Colleges of Pharmacy • American Foundation for Pharmaceutical Education • National Institutes of Health

FIND OUT MORE: For prerequisites and curriculum, visit https://pharmacy.olemiss.edu/medchem Department of BioMolecular Sciences 662-915-7330 • bmschair@olemiss.edu

PHARMACEUTICAL SCIENCES 11

Field of Study

M.S.

Ph.D.

PHARMACEUTICS Pharmaceutics is the art and science of delivering the right amount of therapeutic agents to harmaceutics is the art and science of delivering the right amount of therapeutic agents the right places at the right times. Faculty conducts research to identify problems related to the right places at the right times. Faculty conducts research to identify problems to drugrelated delivery (e.g.,delivery biological barriers, physical andphysical chemical of molecules) to drug (e.g., biological barriers, andcharacteristics chemical characteristics of molecules) and developstosolutions to overcome and develops solutions overcome them. them.

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Research Areas • Cancer biology • Cancer immunotherapy • Co-delivery of chemo drug and siRNA for the treatment of lung cancer • Delivery of immunomodulatory agents for inflammatory disorders • Drug delivery design strategies for ocular delivery • Electrically mediated transdermal and trans-ungula drug delivery, electroporation and transcutaneous sampling (ETS) of drugs • Enhancement of delivery via transporter targeted prodrugs (oral, ocular and transmucosal) • Hot-melt extrusion processing and 3D printing of pharmaceutical products • Intranasal delivery for targeting to brain • Light, redox sensitive prodrug

• Nano-structured systems in transdermal drug delivery • Nanodelivery/tissue-specific delivery • Novel drug delivery systems, including “trans” systems • pH, ionic strength sensitive peptide-based hydrogel • Pharmacokinetics/pharmacodynamics • Polymeric drug delivery design and stabilization of drug delivery systems • Redox, thermal, pH sensitive polymers • Stimuli responsive drug delivery platforms and NCEs • Study of dermatokinetics of drugs • Targeted inhalation delivery of drugs and siRNA using bio-engineered polymeric or lipidic nanoparticles for asthma • Tumor metabolism

External Research Funding • American Foundation for Pharmaceutical Education

• Ligand Pharmaceuticals Inc.

• Ashland Specialty Ingredients G.P.

• National Institutes of Health

• BASF Corp.

• National Science Foundation

• FiteBac SkinCare LLC

• Nemus Bioscience

• KHG fiteBac Technology LLC

• U.S. Food and Drug Administration

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• Marine Polymer Technologies

FIND OUT MORE: For prerequisites and curriculum, visit https://pharmacy.olemiss.edu/pharmaceutics/graduate-programs Department of Pharmaceutics & Drug Delivery 662-915-7341

PHARMACEUTICAL SCIENCES 13

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Field of Study

M.S.

Ph.D.

PHARMACOGNOSY Pharmacognosy is the study of bioactive natural products found in plants, microbes and is the of bioactive natural found in animals,harmacognosy from which nearly halfstudy of all therapeutic agents are products derived. While addressing plants, microbes and animals, from which nearly half of all therapeutic challenges such as the impact of natural products on humans and the environment, agents are derived. While addressing challenges such as the impact faculty and students conduct research leading to new methods for analyzing of natural products on humans and the environment, faculty and students drugs, toxins and herbal preparations; new therapeutic agents, pest controls and conduct research leading to new methods for analyzing drugs, toxins and herbal medicines; and increased understanding of the pharmacology, ecology herbal preparations; new therapeutic agents, pest controls and herbaland biochemistry ofmedicines; molecules produced by nature. and increased understanding of the pharmacology, ecology and

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biochemistry of molecules produced by nature.

Research Areas • Bacterial natural products in the environment

• New antimicrobial and anti-cancer drugs

• CNS-active agents

• Polyphenols from fruits

• Molecular probes for studying drugreceptor interactions

• Semisynthetic modifications of natural products and ecological relations of marine organisms

External Research Funding • American Association of Colleges of Pharmacy • Mississippi Department of Environmental Quality

• National Institutes of Health • National Oceanic & Atmospheric Administration • U.S. Department of Treasury

FIND OUT MORE: For prerequisites and curriculum, visit https://pharmacy.olemiss.edu/bms/divisions/pharmacognosy Department of BioMolecular Sciences 662-915-7330 • bmschair@olemiss.edu

PHARMACEUTICAL SCIENCES 15

Field of Study

M.S.

Ph.D.

PHARMACOLOGY Pharmacology is the study of how chemical agents, including potential therapeutic drugs, act on biological harmacology is the faculty study of how chemical agents, including potential cellular, therapeutic systems.

Our pharmacology and students explore the changes in molecular, drugs, act on biological systems.

Our pharmacology faculty and students and behavioral signaling in response to drugs or other chemical constituents and allows explore for the changes in molecular, cellular, and behavioral signaling in response to drugs the characterization of beneficial effects or adverse consequences (toxicity).

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or other chemical constituents and allows for the characterization of beneficial effects or adverse consequences (toxicity).

Research Areas • Cancer

• Diabetes

• Hypertension

• Cardiovascular and Renal function

• Glycobiology

• Neuroscience

• HIV

• Obesity

External Research Funding • GenNext Technologies Inc.

• U.S. Department of Defense

• National Institutes of Health

• U.S. Geological Survey

• National Science Foundation

FIND OUT MORE:

For andcurriculum, curriculum, Forprerequisites prerequisites and visitvisit https://pharmacy.olemiss.edu/bms/divisions/pharmacology Department https://pharmacy.olemiss.edu/bms/divisions/pharmacology ofDepartment BioMolecular Sciences 662-915-7330 bmschair@olemiss.edu of BioMolecular Sciences 662-915-7330 • bmschair@olemiss.edu

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PHARMACEUTICAL SCIENCES 17

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Field of Study

M.S.

Ph.D.

PHARMACY ADMINISTRATION Pharmacy administration includes pharmaceutical marketing and management, socio-behavioral harmacy administration includes pharmaceutical marketing and management, sciences, and health outcomes research. socio-behavioral sciences, and health outcomes research.

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Research ResearchAreas Areas • Consumer behavior and decision-making

• Pharmaceutical policy

• Drug consumption behavior

• Pharmacy benefit management

• Drug pricing

• Pharmacoeconomics

• Ethics

• Pharmacoepidemiology

• Evaluation of pharmacy interventions

• Pharmacy education

• Health economics and outcomes research

• Pharmacy management

• Health care service delivery

• Pharmaceutical marketing

• Health care technology

• Pharmacist job satisfaction, turnover and quality of work-life

• Health-related quality of life • Medication adherence and persistence

External Research Funding • American Association of Colleges of Pharmacy

• Pharmacy Quality Alliance Inc.

• American Foundation for Pharmaceutical Education

• University of Mississippi Medical Center

• Medical Marketing Economics LLC

• St. Jude Children’s Research Hospital • Wal-Mart Foundation

• National Institutes of Health • Patient-Centered Outcomes Research Institute (PCORI)

FIND OUT MORE: For prerequisites and curriculum, visit https://pharmacy.olemiss.edu/phad Department of Pharmacy Administration 662-915-7262

PHARMACEUTICAL SCIENCES 19

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Apply Apply Today

ADMISSION PROCESS Submit:

• Completed online application with application fee: https://apply.olemiss.edu/graduate • Official transcripts from all four-year and graduate institutions attended • Standardized test scores GRE for Pharmaceutics & Drug Delivery GRE or GMAT for Pharmacy Administration • TOEFL scores for international students • Letters of recommendation • Department requirements such as statement of purpose, resume and interview — check with the individual department for requirements

FINANCIAL ASSISTANCE Opportunities for teaching assistantships, research assistantships and fellowships are available.

Check with the department for availability.

The University of Mississippi does not unlawfully discriminate on the basis of race, color, gender, sex, sexual orientation, gender identity or expression, religion, national origin, age, disability, veteran status or genetic information.

PHARMACEUTICAL SCIENCES 21

Why Ole Miss?

Why Why Ole Miss?

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The University of Mississippi is recognized as a major research institution and is a part of the R-1: Doctoral Universities (Highest Research Activity by the Carnegie Classification of Institutions of Higher Education) group.

Comprehensive in scope yet relatively small in size, the School of Pharmacy’s pharmaceutical sciences programs provide excellent opportunities for advanced studies in a supportive and nurturing environment.

Our graduate students have opportunities to conduct research under the guidance of scientists within our Research Institute of Pharmaceutical Sciences, which comprises four major nationally and internationally renowned entities: • National Center for Natural Products Research • Center for Pharmaceutical Marketing and Management • Pii Center for Pharmaceutical Technology • Center for Clinical and Translational Science

The University of Mississippi School of Pharmacy PO Box 1848 University, MS 38677-1848 Phone: 662-915-7265 Fax: 662-915-5704 PHARMACEUTICAL SCIENCES 23

Listed Best 100 Small Towns in America” and “Best Listedinin“The “The Best 100 Small Towns in America” Small College Town”

by USA Today. and “Best Small College Town”

by USA Today.

Why Oxford?

Why Why Oxford?

The University of Mississippi’s main campus is located in the picturesque city of Oxford, combining the charm and University Mississippi’s main is Touted locatedas inthe the“Cultural picturesque of Oxford, safety of ahe small town withofthe sophistication of a campus larger city.

Meccacity of the South,” creativity combining the charm and safety of a small town with the sophistication of a larger city. abounds in Oxford as musicians, artists and writers alike find inspiration in Oxford’s rich history, small-town Touted as the “Cultural Mecca of the South,” creativity abounds in Oxford as musicians, charm and creative community. Located 75 miles southeast of Memphis, Tennessee, Oxford is easily accessible artists and writers alike find inspiration in Oxford’s rich history, small-town charm and creative from Interstate 55 and is less than a six-hour drive from Atlanta, New Orleans and Nashville.

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community. Located 75 miles southeast of Memphis, Tennessee, Oxford is easily accessible from Interstate 55 and is less than a six-hour drive from Atlanta, New Orleans and Nashville.

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