Medical Fund Newsletter - Spring 2016

Newsletter Spring 2016

1960s Swim Team Returns to Glasgow See Page 3

A Bright Future for Biomedicine in Glasgow See Pages 4 & 5

Medical Fund

UofG Professor Leads Cancer Breakthrough See Page 2

Welcome

UofG Leads Cancer Breakthrough Researchers at the University of Glasgow have made a breakthrough reclassification of Pancreatic Cancer, offering new opportunities to treat the disease. The study was co-led by Professor Andrew Biankin (below), the Regius Chair of Surgery and Director of the Wolfson Wohl Cancer Research Centre and a team at the University’s Institute of Cancer Sciences.

Welcome to our Spring edition of the Medical Fund Newsletter.

The University of Glasgow continues to be at the forefront of clinical research, and you will see that in February we announced a major breakthrough in Pancreatic Cancer research. It is hoped that this world-changing research, jointly led by Professor Andrew Biankin, will lead to more effective and targeted treatments for this devastating type of cancer.

The University is also proud of its international links and world-renowned teaching, and in 2016 we launched the first joint degree programme in Nursing at the Singapore Institute of Technology.

We also highlight again in this issue the Queen Elizabeth University Hospital Teaching & Learning Centre, the brand new University of Glasgow facility that was built in collaboration with NHS Greater Glasgow & Clyde and a variety of industry partners. We would be delighted to welcome you for a behind-the-scenes visit to the building on 22nd June.

In this edition, you will also read about our dedicated supporters. Charlene McEwan has been a supporter of the Brain Tumour Research Fund since she was diagnosed with a brain tumour at the age of 30, and has raised a staggering £60,000 for the Fund. We are delighted to be welcoming the 1960s GU Swim Team back to Glasgow in June for a sponsored swim in aid of the Institute of Health & Wellbeing.

You can read more about this and find out how to support them, on Page 3.

My thanks to everyone who chosen to support the Medical Fund. I hope you enjoy this edition of the Newsletter.

Professor Sir Michael Bond Chair, The Medical Fund 2

Researchers have identified four key subtypes of Pancreatic Cancer which is projected to be the second-leading cause of cancer death in Western societies, within a decade. While all the pancreatic cancers looked similar, there were four classes of genetic error that led to tumour formation: ADEX, Pancreatic Progenitor, Immunogenic and Squamous.

There are a number of key characteristics in each subtype which provide a clue to key vulnerabilities. It means that scientists can target these vulnerabilities. For example, they can modulate the tumour micro environment to allow the host immune system to destroy the cancer.

One of the key findings of the report was the identification of the Immunogenic subtype, which the study found could potentially prove to be responsive to types of immunotherapeutic treatments.

Professor Biankin said: ‘The novel immunogenic subtype of pancreatic

cancer is characterised by specific mechanisms that can potentially be targeted using immune modulators, and testing in clinical trials is encouraged.

This discovery allows us to move forward in finding more effective treatments for improving the outcome for patients’.

Leanne Reynolds, Head of Research for Pancreatic Cancer UK has shown her support for our work, saying: ‘The findings of this research are incredibly exciting for anyone affected by pancreatic cancer, as they should mean that in the future the right patients can be given the right treatment at the right time. This is crucial for people with pancreatic cancer, because the disease is difficult to diagnose, is often diagnosed terribly late, and just four per cent of people live for five years or more after diagnosis.

‘If we can predict more accurately which treatment would be most effective for each patient, we can ensure patients have the best chance of living for as long as possible, as well as possible. We are proud to support Andrew Biankin and his team as they aim to transform the future for people with this disease.’

To support this world-changing research Contact: Catherine McGrory T: +44 (0)141 330 8007 E: catherine.mcgrory@glasgow.ac.uk

1960s Swim Team Returns to Glasgow

On Saturday 4 June we are delighted to be welcoming back to Glasgow the 1960s GU Swim Team.

This team, who are now based all over the world, were a close-knit group that studied a wide range of academic disciplines. Having kept in touch over the years, they have had numerous reunions in Glasgow, and this year are looking forward to getting together to take part in a sponsored swim at the University.

So far 18 swimmers, all now around the age of 70, have agreed to take part, and will be swimming one mile each to raise money for the Institute of Health & Wellbeing (IHW).

Philip Leckie, who graduated in 1969, told us ‘The swimmers enjoyed University sport all those years ago, and greatly benefitted from it. Now we want to “give something back” to our alma mater’.

Research taking place in the IHW is wide ranging and interdisciplinary, including studies into mental health, obesity, smoking, and community health. It is recognised that the IHW continues to make an important contribution towards improving public health and wellbeing in Scotland and further afield.

All funds raised by the 1960s GU Swim Team will go towards the groundbreaking priority projects within the Institute.

To show your support for our septuagenarian swimmers W: www.justgiving.com/ guswimteam1960s

For further information or to find out about taking part Contact: Philip Leckie or Kay Robertson via E: josie.walbaum@glasgow.ac.uk

Tommy Burns Leukaemia Research Dinner

Join us on Saturday 21 May for a new leukaemia research fundraising dinner, named in honour of the former Celtic player, Tommy Burns (above), who died of the illness in 2008. The event will be held in the elegant dining room of Glasgow University Union, and will consist of a four course dinner, entertainment and an auction.

Dr Vignir Helgason of the The Tommy Burns Lab at the Wolfson Wohl Cancer Research Centre is organising the dinner. The lab was named after the ‘Text for Tommy’ campaign that raised over £110,000.

Tickets are £50 each or £400 for a table for ten. All proceeds from the evening will be directed towards the Paul O’Gorman Leukaemia Research Centre in Glasgow.

Further information and tickets W: www.glasgow.ac.uk/pogdinner T: +44 (0)141 330 5092

Remembering Sam Galbraith A new book, ‘Remembering Sam: The Life and Times of Sam Galbraith’ recounts the remarkable achievements of Glasgow’s outstanding medical graduate of 1971.

Sam became a neurosurgeon at the Institute of Neurological Sciences but his wish to make a difference on a wider scale then drew him to politics, and at 42 he became a Labour Member of Parliament.

Although he had been a skilled mountaineer, he had pulmonary fibrosis and within two years had to undergo a lung transplant.

Nevertheless, he went on to hold ministerial posts in Westminster and Holyrood. His achievements included highlighting the relation between deprivation and ill-health and the initiation of the separate, distinctive pattern of the NHS in Scotland.

Sam was made an Honorary Doctor of the University in 2002 and died in 2014.

The book includes memories from family, friends and colleagues, and provides insight into Sam’s character and personality, how he contributed so much and why he inspired

such widespread respect and deep affection.

It will be published in late April and a launch event will be held on Tuesday 7 June. Places at this event are limited and will be allocated on a first come first served basis.

To purchase a copy of the book: www.rememberingsam.co.uk

To attend the launch event Contact: Laura Morton T: +44 (0)141 330 3878 E: laura.morton@glasgow.ac.uk 3

A Bright Future for Biomedicine in Glasgow Over 100 supporters of medical research and teaching at the University of Glasgow joined Professors Anna Dominiczak, Matthew Walters and Keith Muir and the DAO team at the Queen Elizabeth Teaching & Learning Centre in November 2015 for a behind-the-scenes look at the brand new purpose-built University of Glasgow facilities at QEUH. Guests were informed that the University has partnered with the NHS Greater Glasgow & Clyde (GG&C) and industry partners to lead the development of innovative diagnostic and precision medicine and to deliver research-led training of tomorrow’s doctors.

Guests were also given a tour of some of the new facilities which include: • A clinical research facility which ensures that the Queen Elizabeth University Hospital is at the forefront of clinical trials of new medicines.

• The Teaching & Learning Building was purpose-built for the training of undergraduate and postgraduate medical, nursing and other biomedical students alongside NHS staff. This building also includes a dedicated innovation floor which accommodates Stratified Medicine Scotland Innovation Centre, a University of Glasgow-led, Scotland wide, collaboration with industry which is developing precision medicine – advances diagnostic and precise treatments for individuals across a wide range of chronic diseases.

• The Imaging Centre of Excellence (ICE) building is currently under construction and when complete will include a 7 Tesla MRI scanner which will be first of its kind on a clinical site in the UK. It will also house world leading clinical academic expertise in stroke, cardiovascular disease and brain imaging.

Ultimately, the impact of the University of Glasgow partnerships with NHS GG&C will extend to all UK citizens through the research led training of tomorrow’s doctors and the development of innovative diagnostics and medicines.

Professor Dominiczak said ‘What makes this new hospital so exciting is the “triple helix” partnership between the NHS, University and industry. We have a world-leading University working with a forward-thinking health board and access to some of the brightest and best industry partners on earth’.

The University’s facilities at the QEUH were made possible by a range of funding including government, European and philanthropic funds.

Below Left Part of the tour at the Queen Elizabeth Teaching & Learning Centre.

The new hospital is the result of a ‘triple helix’ partnership between a world-leading University, a forward-thinking health board and some of the brightest and best industry partners on earth.

Book your place on the next tour of University facilities at QEUH Contact: Laura Morton T: +44 (0)141 330 3878 E: laura.morton@glasgow.ac.uk 4

Behind-the-Scenes at the Queen Elizabeth University Hospital Left Professor Anna Dominiczak addresses guests at the QEUH. Above & Below Guests were given an insight into the University facilities at the new hospital.

Top Dr David and Mrs Carole Walton from The Walton Foundation are pictured above during a recent visit to view the Walton Foundation Teaching Suite.

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Raising Funds for Brain Tumour Research

New UofG-SIT Joint Nursing Degree

The University of Glasgow and the Singapore Institute of Technology (SIT) are launching a new joint degree programme in Nursing.

The Bachelor of Science with Honours in Nursing is SIT’s first joint degree in partnership with the University of Glasgow. It is also one of the seven new degree programmes to be launched by SIT in 2016.

The President of SIT, Professor Tan Thiam Soon, and the Principal & ViceChancellor of the University of Glasgow, Professor Anton Muscatelli, took part in a formal signing ceremony earlier this year at the Principal’s Lodgings.

The University and SIT have been working in partnership since 2011 and the University of Glasgow Singapore (UGS) was the University’s first subsidiary outside Scotland in its 560-year history.

Post Doctoral Research Associate, Dr Shafiq Ahmed, with Charlene on her visit to the lab.

We were delighted to welcome Charlene McEwan to the Wolfson Wohl Cancer Research Centre in December to present her cheque of £7,500 to Professor Anthony Chalmers. This was a result of Charlene’s most recent fundraising night in Wishaw which took place in November.

Charlene has now raised over £60,000 for brain tumour research at the University of Glasgow and is determined to raise more. Charlene, who visited the centre with her husband said ‘Tosh and I were in absolute awe to see first-hand the work Professor Chalmers and his amazing team are doing’.

Charlene was diagnosed with a brain tumour at the age of 30. Since then, she has been busy running numerous events to raise funds for brain tumour research in Professor Chalmers’ laboratory.

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Donations help the brain tumour research team to do exploratory studies in the laboratory that pave the way for larger projects and help to get large grants from funding bodies like Cancer Research UK and the Medical Research Council. They make a real difference to the ability of scientists to compete with other research groups around the UK to secure funding and develop research that will have a make a positive difference for patients with brain tumours.

Charlene has raised over £60,000 for brain tumour research at the University.

New Nursing Professorship Professor Bridget Johnston has been appointed the Florence Nightingale Foundation Chair in Clinical Nursing Practice Research. Professor Johnston has an international reputation and experience of leading multiprofessional research teams focusing on palliative and supportive care.

The new Professorship is a welcome partnership between the University, the NHS Greater Glasgow & Clyde and the Florence Nightingale Foundation, their first such post in Scotland.

Professor Anna Dominiczak said ‘Our colleagues in Nursing & Health Care are delighted about Professor Johnston’s appointment, which represents an opportunity to grow research capacity and strengthen outputs that translate research directly into clinical care, support innovation and enhance the patient experience’.

Thanks to All Our Donors Thanks to all those who made gifts to the Medical Fund from 1 October 2015 to 31 March 2016.

Arthritis • Platinum • The Estate of Ann Maria Wetton • Bronze • Kirsty Craig • Noted • Jane R Hamilton Brain Tumour Research Fund • Major • Bare For All Brain Tumours • Gold • From David, Nicola, Christy, family and friends in memory of Gail Docherty 23/09/66 -12/11/15 • In loving memory of Aidan O’Neill^ • Silver • In memory of Gail Docherty • Elizabeth M Tait • Bronze • One anonymous donor^ • Noted • Two anonymous donors • Kate Guest • Alison Sharp Critical Care • Noted • One anonymous donor • Julia M Cullen Dentistry • Silver • One anonymous donor • Dr David D Reaka • Bronze • In loving memory of Alfred and Frances Luffingham • William McBurney • Noted • John Robinson Grant • Robert M Thomson Diabetes • Silver • Dr James C Smith^ Diseases of the Nervous System • Major • The Estate of Dr William Campbell Love • Gold • In memory of Dr Margaret J Fingland^ • Noted • Patrick Kane • Emma J Sloan General Medical Fund • Major • Dr Andrew S Barr and the late Margaret J Stirling B.D.S • The Estate of Dr Gething Morgan Lewis • Dr Charles and Marilyn Wright • Gold • In memory of Neil Burgess^ • Silver • Dr John Baillie and Dr Alison H Baillie†^ • Bjørn L Hoel

• Chloe L Kippen • Alexander Miller • Anne M Walters • Bronze • Two anonymous donors • Susan Chalmers • In memory of Frank, Fred & Fred, who taught me that knowledge isnt always academic.

• Lynn G Gibson^ • In loving memory of Gaye Hendry from Osman and Gillian^ • Elizabeth A Johnston^ • In memory of my late wife, Catherine Elizabeth Jugdutt (née Graham) • Mary McDonald • Ruth Rae • Dr Robert C Robb^ • Dr Steven Wishart • Noted • Iain Kane • Finlay Kerr • Fraser MacLeod • Kenneth Wallace Geriatric Research • Major • The DWT Cargill Fund Guillain Barre Syndrome (GBS) Research • Silver • In celebration of Allan Reid & Ronald Stalker’s joint 40th birthdays Heart Disease: Heart Attack & Stroke • Platinum • Dr Douglas & Dr Eleanor Briggs^ • Silver • One anonymous donor^ • Martin & Norah McLachlan • Dr Kenneth L McGeoch^ • Bronze • Charles F Norris • Marslaidh Catherine Scott • Noted • Alistair Finlay • In fond remembrance of Helen Rowan Gray & Elsie May Adams • David Millar Immune & Inflammatory Diseases • Silver • Sheila M Craik • Dr Andrew J Manchip Medical Education Fund • Platinum • The Estate of Dr A J Hale (Hamish) • Silver • Dr Chua Tju Siang • Bronze • In memory of my beloved and dearly missed father Dr Ali Mahawish • Noted • Glasgow University Delta Club 1970 Mental Health • Silver • Dr Alastair C Glen^ • Dr Andrew J Manchip^

• Bronze • In memory of Dr Margaret J Fingland • Noted • One anonymous donor • Hilary Easton • Kate Guest Myotonic Dystrophy Research • Major • Myotonic Dystrophy Support Group Paediatrics & Maternal Health • Silver • One anonymous donor Beatson Pebble Appeal • Major • The James & Patricia Hamilton Charitable Trust • Platinum • Dr Douglas & Dr Eleanor Briggs^ • R N Goacher^ • Port William & District Bridge Club^ • Sheriff Marie T Smart • Bette Stone • Gold • One anonymous donor • The Phoenix Car Company^ • Dr Catherine A Richards^ • Ian Rutherford^ • Paul Stonelake & Jemarie Ignacio†^ • Silver • Two anonymous donors • With thanks to Dr Alhasso and his team • Dr James D Campbell • David J Ferguson^ • Drs Ian & Margaret Fingland • James Frame • In memory of Isabel Ross Ghaleb (nee Graham)^ • Dora Mann • In memory of Douglas McCulloch • Inez Murray • For Pat^ • Paul Russell • Colin Steele • Alexander Stewart^ • Bronze • Three anonymous donors • John M Allison^ • Helen Blythe • Brothers from Another Udder • Elizabeth Calder^ • Donald Campbell • Alison Lannigan & Juliette Murray • Alastair J MacDonald • William McDougall^ • Fiona M McGlynn^ • Ann Mitchell • James R B Robertson^ • Anne Sharky • Eileen H R Wilkie^ • Noted • Five anonymous donors • Margaret and Robert Baird^ • Agnes McRae Robertson Blair • In memory of Susan R Cameron, Ardrishaig 10/04/1947-28/05/2015 • Anne Fuller

• Patricia Gillespie • Dr Eileen Margaret Henderson • In memory of Alan & Jeanette Hotchkiss • In memory of Doris Hutson (nee Kemp) (1926-2014), Glasgow graduate 1949 • In memory of my son Ian • Ian & Ann Lee • Carol A MacBeth • Agnes C F McIlwraith • Malcolm Nimmo Paul O’Gorman Leukaemia Research Centre • Major • Tessa Laurie Holyoake FRSE • Team McGuigan • The Laura McKee Leukaemia Trust • Mackenzie Family^ • Alexander McKenzie • Jim & Rena Smith^ • Platinum • Dr Douglas & Dr Eleanor Briggs^ • Gold • Penny Haydock • Chris Wallace • Silver • A Cocozza • Alison Fitzsimons, Colin Gregor, Lindsay McSkimming, Christine Nelson, Kimberley Nelson • Forth Breast Cancer Care Group • Glasgow University Rugby Football Club • My sister-in-law Anne Paxton - a fighter • Denise Seix • Annie M Sloan^ • Bronze • Anne & Jim Malloch^ • In loving memory of Anne Robertson^ • Stornoway Golf Club • Donald Stott • Noted • One anonymous donor • Envirocentre Ltd • Shannon Gilchrist • Niamh Mannion • David & Catriona MacLennan • Ms J.P.L. McColl • Iain Riddell • Anilah Sadiq • Doreen Elizabeth Scott • Mansi Shah • In memory of Jessie Skinner loving mother, grandmother & great grandmother • David Thomson • Bill Wright Think Pink Scotland • Noted • Kate Guest • Trinity High School Class 3H Administration & IT 2015 ^Denotes gift upgraded † Denotes American Alumni of Glasgow University gift

Make a Gift to the Medical Fund Find out how you can support future generations of doctors, and contribute to the vital work of our researchers at www.glasgow.ac.uk/givingtoglasgow

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