Differentiators in Cardiovascular Care

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Differentiators IN CARDIOVASCULAR

CARE

2023 FY 2022 DATA*

FRANKEL CVC U.S. NEWS & WORLD REPORT RATINGS

U.S. News and World Report annually judges hospitals for its Best Hospitals list by rating high-quality patient care, commitment to patient safety, clinical resources, familycenteredness and other measures.

For 2022–23, Michigan Medicine has been ranked number 26 in the nation for Cardiology and Heart Surgery. The Frankel Cardiovascular Center’s scores include “High Performing” ratings in six conditions/ procedures: Heart Failure, Abdominal Aortic Aneurysm Repair, Aortic Valve Repair or Replacement, Heart Bypass Surgery, Transcatheter Aortic Valve Replacement (TAVR), and Heart Attack.

University of Michigan’s hospitals were ranked among the nation’s very best hospitals at No. 17, including being No. 1 in the state and the only Michigan hospital named to the nation’s Honor Roll of hospitals.

Thanks to the teamwork, innovation and excellence of our employees, this is the 30th consecutive year that U-M Health has been nationally recognized for strong across-the-board performance.

2,089 ADULT OPEN SURGICAL VOLUME

80,953 CLINIC VISITS

2 ,511 ARRHYTHMIA CASES

4,962 CARDIAC CATHETERIZATION CASES

6, 277 INPATIENT DISCHARGES

96.6% FRANKEL CVC CLINICS OVERALL RATING OF CARE

UNIVERSITY OF MICHIGAN HEALTH NAMED A 2022 LEAPFROG TOP TEACHING HOSPITAL

The Leapfrog Group has named University of Michigan Health one of its 2022 Top Teaching Hospitals. Each year, the organization recognizes hospitals that have achieved “true excellence” and honor them with being named one of their top hospitals. In order to achieve this distinction, hospitals must meet the nation’s toughest standards for safety and quality.

From the Frankel CVC Leadership .......................................................... 1 Arrhythmia Management 2 Aortic Disease .......................................................................................... 4 Heart Failure Continuum of Care 6 Cardiac Valve Disease ............................................................................. 8 Complex Coronary Disease 10 Cardiovascular Imaging 12 Pulmonary Vascular Disease 14 Preventive Cardiology 15 Key Service Areas of Excellence 17 Procedural Volumes 25 Research ................................................................................................. 26 Education 28 Your Resources ...................................................................................... 30 Locations 32
Contents
BY2022 THE NUMBERS
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*Frankel CVC Fiscal Year 2022: July 1, 2021 through June 30, 2022

FROM THE Frankel CVC Leadership

Dear Colleagues,

We are proud to present the 2022 Samuel and Jean Frankel Cardiovascular Center Differentiators report. As always, our goal is to provide you with important medical information that is easily accessible for you and beneficial for your patients. This report highlights our advancements and innovations in the treatment of cardiovascular disease and underscores our unique strengths.

Teamwork first

Our Frankel CVC specialists are committed to the highest standards of care, working hand in hand as a multidisciplinary team. Each team member brings a range of experience and knowledge to ensure comprehensive, individualized care and optimum outcomes for each and every patient.

Personalized treatment

Using cutting-edge scientific evidence and our clinical expertise, we are able to offer patients more personalized treatment choices than ever before. Our specialized programs are designed to tailor treatment for cardiovascular conditions ranging from the simplest to the most complex.

Patient-centered care

At the heart of the Frankel CVC lies the belief that providing the ideal care experience stems from a partnership between patients, their families, physicians, and staff. Our treatment plans take into consideration the patient and family’s experience, values, needs and preferences, giving them a voice in the management and delivery of their care.

Setting the standards

Our involvement in developing the guidelines for many cardiovascular conditions, including stroke, hypertension and aortic disease, enables us to effectively diagnose and treat the full spectrum of cardiovascular issues with the latest therapies.

Research and discovery

Our commitment to research keeps us at the forefront of scientific discovery and ensures patients have access to a full range of important clinical research studies available at the Frankel CVC.

Building for tomorrow

Looking toward 2025, the D. Dan and Betty Kahn Health Care Pavilion at University of Michigan Health represents a crucial investment in advancing health care to patients throughout the state and beyond. The 12-story hospital will house 264 private rooms capable of converting to intensive care; a state-of-theart neurosciences center; and high-level, specialty care services for cardiovascular and thoracic patients.

The Frankel CVC continues to uphold our important position in shaping the future of cardiovascular care. Through our partnership with you, our referring physicians, we will continue to provide the most advanced, personalized care to patients throughout Michigan and beyond. As always, we look forward to your feedback.

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Arrhythmia Management

The Comprehensive Arrhythmia Program is a highvolume tertiary referral center for the management of the most complex cardiac arrhythmias complemented by a robust clinical research program. Partnering with Frankel CVC’s state-of-the-art imaging program, our faculty use comprehensive MRI, CT and/or PET imaging to inform treatment planning and guide procedures.

For over 30 years, U-M has been an international leader in complex arrhythmia ablation. Through groundbreaking clinical trials, our experts have helped perfect the tools used in ablation and shaped the standard of arrhythmia care. We have expertise in high-risk epicardial ablation to treat ventricular tachycardia and stereotactic ablation for patients for whom catheter ablation is not indicated.

Our team partners with neurology to provide a multidisciplinary evaluation and treatment plan for patients with non-valvular atrial fibrillation who would benefit from left atrial appendage occlusion devices. Our robust program features experts in catheter-based percutaneous and video-assisted thorascopic surgical left atrial appendage occlusion or exclusion, ideal for patients who are at risk for heavy bleeding and/or frequent falls.

The Frankel CVC leads the state in performing laser lead extractions, a high-risk, complex procedure to remove broken, malfunctioning, or infected pacemakers or defibrillator wires. Our high volume leads to significantly better patient outcomes.

U-M Health was the third hospital in the world and the first in Michigan to implant the most recent version of the world’s smallest leadless pacemaker. Our experts are driving the next generation of pacemakers — an even smaller device is currently in clinical trials.

READ ABOUT a constant state of afib: michmed.org/ DymMe

2 n FRANKEL CARDIOVASCULAR CENTER UMCVC.ORG

Recent advances in high density electroanatomic mapping catheters and software allowed for successful identification, and subsequent ablation, of a focal atrial tachycardia on the posterior left atrial wall near the left pulmonary veins.

SETTING THE STANDARD FOR TREATING ARRHYTHMIAS FOR THE LAST 30 YEARS

#1 IN MICHIGAN FOR LASER LEAD EXTRACTIONS

>1,000 CATHETER ABLATIONS PER YEAR

M-LINE: 800-962-3555

>400 CARDIAC DEVICE IMPLANTS PER YEAR

#1 IMPLANTER OF LEADLESS PACEMAKERS IN MICHIGAN

DIFFERENTIATORS IN CARDIOVASCULAR CARE n 3

Aortic Disease

The Comprehensive Aortic Disease Program, established more than 25 years ago, is one of the largest practices in North America, with specialists providing unparalleled expertise in advanced open and endovascular procedures to treat aortic disease. Our multidisciplinary team includes experts from cardiac surgery, vascular surgery, interventional radiology and diagnostic radiology. Collaboration among specialists and shared decisionmaking between patients and surgeons on timing and approach for aortic surgery are key to our excellent patient outcomes.

MI-AORTA, a recent initiative launched with generous donor support, aids the growth of our highly regarded aortic disease clinical practice, training and research program into a world-renowned enterprise. Within our aortitis center to treat inflammatory and autoimmune conditions of the aorta, we launched a new noninvasive

diagnostic program using novel large vessel ultrasound techniques to identify giant cell arteritis, sparing the need for surgical biopsy; our vascular lab is one of only a few labs in the U.S. offering these studies. MI-AORTA facilitates collaboration within U-M Health, creates value for patients, and allows us to continue to pioneer advanced therapies for aortic disease.

From medical management to minimally invasive endovascular and open surgical procedures, our specialists treat the full spectrum of aortic disease. Frankel CVC surgeons are among the world’s leading experts in bicuspid aortic valve disease and aortic root disease. Our unique hybrid endovascular/surgical approach, developed here to treat complicated and chronic aortic dissection yields better patient outcomes and allows us to deliver mortality rates among the lowest in the country

HIGH PERFORMANCE RECOGNITION FOR ABDOMINAL AORTIC ANEURYSM REPAIR

1,200 AORTIC AND AORTIC VALVE PROCEDURES EACH YEAR

HIGH VOLUME OF INNOVATIVE TREATMENTS TRANSLATES TO EXCELLENT OUTCOMES

TYPE A AORTIC DISSECTION OPERATIVE MORTALITY SIGNIFICANTLY LOWER THAN NATIONAL BENCHMARK 10.1% vs. 14.8%

EVAR AND ABDOMINAL AORTIC ANEURYSM MORTALITY OUTCOMES ARE SIGNIFICANTLY BETTER THAN PUBLISHED GUIDELINES

7 MINIMALLY INVASIVE AORTIC-RELATED TRIALS

4 n FRANKEL CARDIOVASCULAR CENTER UMCVC.ORG
3D CT rendering of the thoracic aorta following aortic stent graft intervention in a patient with aortic dissection

Our vascular surgeons use novel methods to extend the treatment of complex aortic aneurysms through 3D printing, physician-modified endografts, and ongoing enrollment in clinical trials of thoracoabdominal aneurysm stent grafts. Faculty are experts at salvaging failing endografts through management of endoleaks and extension of endografts through the aortic branches. Our aortic specialists were the first in the U.S. to implant the newly FDA-approved GORE TAG single side branch thoracic stent endograft.

We offer genetic screening and counseling to help patients and their families understand their risk for aortic disease and collaborate with international research consortiums focused on identifying and understanding genetic mutations that affect aortic disease.

Our world-renowned researchers, funded by the NIH and other entities, are advancing the science of aortic disease evolution and progression, resulting in critical breakthroughs in understanding the pathophysiology that may lead to treatments without the need for surgery. Participation in clinical trials — including seven current minimally invasive aortic-related trials — gives patients access to leading-edge care which would not otherwise be an option.

For information about our many active clinical trials, visit UMHealthResearch.org.

DIFFERENTIATORS IN CARDIOVASCULAR CARE n 5
M-LINE: 800-962-3555

Heart Failure CONTINUUM OF CARE

The multidisciplinary Heart Failure Program provides expert medical management, advanced surgical care and comprehensive rehabilitation for adult and pediatric patients at all stages of heart failure. We are a world leader in mechanical circulatory support and heart transplantation.

The Center for Circulatory Support houses our internationally recognized ventricular assist device (VAD) program. As one of the few programs worldwide that participates in nearly every VAD-related investigational and FDA-approved clinical trial, our patients have access to next-generation devices and technologies that extend post-implant survival and improve outcomes. A world leader in VAD research and development, the Frankel CVC is a regional and national referral center for adult and pediatric patients with end-stage heart failure or cardiogenic shock. To continue to advance the care of critically ill patients with heart failure, we have partnered with the International Consortium of Circulatory Assist Clinicians to create VAD-C,™ a certification program for clinicians that elevates the quality of care received by VAD patients.

The University of Michigan is the birthplace of extracorporeal membrane oxygenation (ECMO). Our Extracorporeal Life Support Organization (ELSO) Gold Certified Center of Excellence ECMO program provides ECMO across the entire lifespan. We care for approximately 150 ECMO patients annually in five ICUs across U-M Health; 50% of these patients are housed in the Frankel CVC. A team of ECMO-certified critical care nurses and respiratory therapists provide 24/7 in-house ECMO coverage, emergently responds to ECMO needs anywhere on our main hospital campus, and partners with Survival Flight to cannulate and transport critically ill patients to U-M Health from outside facilities.

The internationally-recognized U-M Health Adult Heart Transplant Program is implementing initiatives to expand the volume of heart transplants and reduce transplant waitlist time. With recent advancements in

READ HOW her heart stopped more than 25 times. ECMO saved her life: michmed.org/GyzZg

oral antiviral therapy we have initiated a new protocol that allows select patients to accept hearts from donors with active hepatitis C infection and be treated postoperatively to fully eradicate any potential transmission of the virus. Our recent acquisition of the TransMedics® Organ Care system, which preserves donor hearts longer, allows utilization of donor hearts from distances that were previously prohibitive. We are also the first center in Michigan to create an infrastructure for donation following circulatory death (DCD), which allows a heart to be transplanted from a donor who has been declared dead using circulatory criteria but does not meet formal brain death criteria.

Our renowned specialists provide advanced treatment for cardiac sarcoidosis, transthyretin amyloidosis, and hypertrophic obstructive cardiomyopathy. These rare, difficult-to-diagnose conditions require unique expertise and imaging studies. Early referral and diagnosis allows us to offer treatment options not available at lessspecialized centers and optimizes patient outcomes. Our robust clinical trials program provides early access to options such as tafamidis, the only FDA-approved medication to treat transthyretin amyloid cardiomyopathy. The Frankel CVC was the first enrolling site globally and the only site in Michigan for the ATTR-ACT clinical trial of this groundbreaking therapy.

The Frankel CVC offers personalized treatment plans for patients with heart failure with preserved ejection fraction, or HFpEF. We are the only site in Michigan participating in the RESPONDER and BALANCE-HF clinical trials which offer breakthrough device-based care options for this challenging patient population.

A unique U-M Health inpatient heart failure service at Chelsea Hospital, in partnership with Trinity Health gives patients access to Frankel CVC heart failure specialists, closer to home. The program provides intensive education and support to patients and family members during their stay and after discharge.

For information about our many active clinical trials, visit UMHealthResearch.org

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AWARDED DISEASE-SPECIFIC CARE CERTIFICATION FOR VENTRICULAR ASSIST DEVICES BY THE JOINT COMMISSION IN 2008 AND CONSISTENTLY RECERTIFIED SINCE

1,360 U-M VAD TICKER

1,360 VADs IMPLANTED AND COUNTING SINCE 1996

HIGH PERFORMANCE RECOGNITION FOR HEART FAILURE

5 YEAR VAD SURVIVAL NEARING 60% WITH HEARTMATE 3 VAD

990 HEART TRANSPLANTS SINCE 1994

DIFFERENTIATORS IN CARDIOVASCULAR CARE n 7
M-LINE: 800-962-3555

CARDIAC Valve Disease

Our multidisciplinary team is a national leader in cardiac valve disease. Our extensive minimally invasive and transcutaneous heart valve programs were built upon our decades-long reputation for excellence in surgical valve procedures. We offer patients the latest open surgical and percutaneous options for all valve conditions and specialize in the management of cardiac valves over a lifetime.

The University of Michigan has long been at the forefront of aortic valve surgery. Today, the Frankel CVC offers patients a variety of minimally invasive treatment options, including cutting-edge transcatheter valve repair and replacement techniques. We consistently earn national recognition as “High Performing” in aortic valve repair or replacement and transcatheter aortic valve replacement (TAVR) by U.S. News & World Report in its annual quality and safety rankings.

We are an internationally recognized leader in aortic valve repair for patients with aortic insufficiency or aortic root aneurysm. Our team developed a novel aortic annular enlargement technique for patients needing aortic valve replacement. Approximately half of our surgical aortic valve replacement cases benefit from annular enlargement, allowing us to use larger prosthetic valves to achieve improved patient outcomes.

The Frankel CVC offers the most comprehensive tricuspid valve treatment program in the state founded on excellent outcomes with a breadth of minimally invasive and conventional surgical options. Additionally, we are one of the few centers nationally to participate in a broad spectrum of percutaneous repair and replacement clinical trials. This includes valve replacement, edge to edge repair, and annuloplasty devices for the treatment of tricuspid valve disease, enabling us to provide appropriate patients access to next-generation technologies.

HIGH PERFORMANCE RECOGNITION FOR TAVR EXPERT

HIGH PERFORMANCE RECOGNITION FOR AORTIC VALVE SURGERY

As one of the largest and longest-standing mitral valve centers in the country, and the largest in Michigan, the Frankel CVC is nationally recognized for expertise in mitral valve repair and treatment. U-M Health was among the first five medical centers in the U.S. to receive a Mitral Valve Repair Reference Center Award based on our high volume of mitral valve procedures, superior clinical and patient outcomes, and the highest mitral repair

For information about our many active clinical trials, visit UMHealthResearch.org.

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RN Clinical Care Coordinators Clinical Research Team Quality & Safety Specialists 5 Interventional Cardiologists Cardiac Anesthesiologists Advanced Heart Failure Specialists Advanced Practice Providers 5 Aortic Surgeons IMAGING SPECIALISTS: Echocardiologists Radiologists Nuclear Medicine Imaging Specialists 3 Mitral Surgeons
INTEGRATED HEART TEAM APPROACH FOR THE MANAGEMENT OF VALVE DISEASE

rates. Surgical procedures are commonly performed via minimally invasive techniques without sternotomy. With numerous approved and clinical trial percutaneous repair and replacement devices available to treat all aspects of mitral valve disease, we offer patients an extensive range of treatment options

Through our robust clinical trials program, patients who are not candidates for commercially approved transcatheter and/or surgical therapies have access to a wide variety of alternative treatment options not available at other sites in Michigan. The Frankel CVC is currently participating in 18 valve trials.

U-M Health is pioneering the use of ShortCut™ technology to split bioprosthetic aortic valve leaflets for patients who are at risk for TAVR-induced coronary artery obstruction following a valve-in-valve procedure. We are among the first five programs in the U.S. to use this technology to treat patients with failing aortic valves and difficult aortic anatomies.

2,388

RECOGNIZED

FOR BEST PRACTICES IN MITRAL VALVE REPAIR

U-M TAVR TICKER

2,388 AORTIC VALVES REPLACED AND COUNTING

CURRENTLY PARTICIPATING IN 18 VALVE

CLINICAL TRIALS

TAVR: 5 MITRAL: 8 TRICUSPID: 5

DIFFERENTIATORS IN CARDIOVASCULAR CARE n 9
M-LINE: 800-962-3555

Coronary Disease

Complex coronary disease specialists at the Frankel CVC have expertise in advanced treatments, ranging from open surgical and percutaneous revascularization to specialized medical management. We care for a large volume of high-risk and complex patients who have limited treatment options.

A dedicated heart team of cardiac surgeons, interventional cardiologists, and critical care specialists collaborate in multidisciplinary conferences to develop individualized, evidence-based treatment plans to optimize outcomes for patients with multi-vessel disease.

A high percentage of our percutaneous coronary intervention (PCI) patients have one or more highly complex coronary lesion features, including left main coronary artery location, in-stent restenosis, and significant calcification.

As one of the few teams in the state with expertise in the catheter-based treatment of chronic total occlusions (CTO), we offer advanced, clinically proven, minimally invasive solutions to improve quality of life for patients with chronic angina or cardiac dysfunction.

For patients with in-stent restenosis or stent failure, our interventional cardiologists offer optimization techniques including coronary brachytherapy. By directing radiation inside the affected vessel our team can remediate the stent and prevent recurrent stent failure. The Frankel CVC is one of only four coronary brachytherapy programs in Michigan, backed by the expertise of practitioners who are at the forefront of medical innovation.

Older patients with coronary disease are more likely to have significant calcification not amenable to conventional angioplasty balloons and stent placement. We offer minimally invasive treatment options that remove obstructive calcium to obtain optimal outcomes, including atherectomy and intravascular lithotripsy

Our surgical complex coronary intervention team has exceptional expertise in multi-arterial grafting and performs bilateral internal mammary artery grafting procedures 2.5 times more often than the national average. We also perform a high volume of complex redo coronary artery bypass graft (CABG) surgeries in patients with failed prior bypass.

Despite our high-risk patient population with complex disease and comorbidities, patients undergoing bypass surgery at the Frankel CVC:

• Require significantly fewer blood product transfusions

• Are liberated from the ventilator within the first six hours post-surgery more often

• Are less likely to suffer a stroke or death postoperatively

We have been rated a 3-star program — the highest category of quality — by the Society of Thoracic Surgeons. The Frankel CVC consistently earns national recognition as “High Performing” in heart bypass surgery by U.S. News & World Report in its annual quality and safety rankings.

For information about our many active clinical trials, visit UMHealthResearch.org.

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COMPLEX

A patient with a high-risk stenosis involving the distal left main and left anterior descending arteries.

HIGH PERFORMANCE RECOGNITION FOR HEART BYPASS SURGERY

BILATERAL INTERNAL MAMMARY ARTERY GRAFTING PROCEDURES ARE PERFORMED

Complete revascularization after percutaneous coronary intervention of the left main and left anterior descending arteries. The procedure was completed with the aid of a mechanical support device to provide temporary cardiac support in the setting of a complex intervention.

2.5x MORE OFTEN

THAN THE NATIONAL AVERAGE: 19% vs. 7.6%

STS BENCHMARK JAN–JUN 2022

PATIENTS ARE LIBERATED FROM A VENTILATOR WITHIN THE FIRST 6 HOURS

POST-SURGERY

A patient with a complex left anterior descending stenosis resulting in severe ischemic heart disease.

MORE OFTEN THAN THE NATIONAL AVERAGE: 72% vs. 61%

STS BENCHMARK JAN–JUN 2022

TOP SUCCESS AND SAFETY RATES IN COMPLEX AND CTO INTERVENTIONS

Complete restoration of coronary blood flow after percutaneous revascularization.

THREE-STAR RATING FOR ISOLATED CABG

M-LINE:
DIFFERENTIATORS IN CARDIOVASCULAR CARE n 11
800-962-3555

CARDIOVASCULAR Imaging

State-of-the-art imaging services are at the heart of the Frankel CVC’s heart and vascular programs and research enterprise. Imaging specialists with specialized training and the highest level of credentialing use advanced techniques to provide unparalleled levels of detail, including imaging of the most complex cardiac diseases. Strong interdisciplinary collaboration with specialists throughout the Cardiovascular Center and U-M Health ensures effective diagnosis, analysis and treatment for patients.

Cardiovascular images can be transferred electronically to promote provider to provider and patient to provider communication with Frankel CVC clinical cardiologists.

NUCLEAR CARDIOLOGY AND PET IMAGING CENTER

• The center is equipped with the latest SPECT/CT and PET/CT imaging systems that enable the most precise measurement of blood flow to heart muscle. Frankel CVC specialists employ novel approaches to detect and quantify blood flow abnormalities due to coronary artery disease as well as inflammation in the heart muscle due to cardiac sarcoidosis, myocarditis and cardiac infection.

• A new fully digital PET/CT imaging system offers double the resolution with 50% lower radiation exposure than prior technologies. The digital PET/CT is also faster than traditional SPECT/CT, reducing stress testing time from three hours to approximately 30 minutes.

• With a decade of PET experience, the Frankel CVC is the largest PET program in Michigan.

Right: 3D echocardiography modeling

ECHOCARDIOGRAPHY

• U-M Health’s Echocardiography Laboratory is a nationally recognized leader in cardiac imaging

• Our team of highly trained, board-certified interpreting cardiologists, cardiac sonographers, exercise physiologists, and nurses provides the highest quality specialized care to more than 40,000 patients annually

• The state-of-the-art imaging center offers the most advanced echo imaging modalities available Services include transthoracic, transesophageal, stress (exercise and pharmacologic) echocardiography, 3D echocardiography, and strain analysis.

• Expert 3D echocardiography is the preferred imaging modality for measuring heart pumping function in complex cardiac cases.

CARDIAC AND VASCULAR CT

• Next-generation CT scanners image with lower radiation doses and can capture the entire heart in a single heartbeat. Advanced computer processing helps reduce artifact and improve image quality.

• Advanced image processing specialists in our 3D imaging lab are dedicated to sophisticated postprocessing of CT and MRI datasets to gain accurate dimensions and create 3D printed models of vascular anatomy. These models can inform planning of aortic and structural heart interventions and aid in patient education.

• We also offer advanced imaging techniques like dual energy CT for patients with chronic thromboembolic pulmonary hypertension.

12 n FRANKEL CARDIOVASCULAR CENTER UMCVC.ORG
Left: FDG-PET reveals focal intense FDG uptake involving the mechanical aortic valve replacement, suggestive of active inflammation and prosthetic valve infection.

FROM FY20 TO FY22

50% LOWER

ACCREDITATION COMMISSION

• Frankel CVC researchers recently developed a technique using machine learning and high-resolution CT scanning to calculate 3D changes in the aortic wall that may help clinicians identify aortic aneurysms earlier when they are more easily treatable.

CARDIAC MR

• Frankel CVC’s magnetic resonance scanners are equipped with the latest technology to skillfully demonstrate cardiovascular anatomy; accurately measure cardiac function, shunt quantification and stress perfusion; assess valvular pathologies; and identify areas of cardiac scarring — all critical steps in planning advanced cardiac interventions. We also perform MR imaging in patients with pacemakers and ICDs, regardless of whether the device is MRI conditional.

DIAGNOSTIC VASCULAR ULTRASOUND (DVU)

• Our DVU certified sonographers perform a full spectrum of approximately 30,000 arterial, venous, cerebrovascular, and abdominal studies annually, including air plethysmography, transcranial doppler monitoring, transcutaneous oxygen measurement, specialized pelvic venous studies, specialized temporal artery duplex for diagnosis of giant cell arteritis, arterial perforator mapping prior to fibular flap surgery, and pediatric studies.

• Accredited by the Intersocietal Accreditation Commission since 1993.

Heart model created from CT dataset in a 73-year-old female with sinus venosus defect and anomalous pulmonary venous drainage. This innovative technique enabled interdisciplinary collaboration and preprocedural planning.

DIFFERENTIATORS IN CARDIOVASCULAR CARE n 13
M-LINE: 800-962-3555
SINCE 1993
ACCREDITED BY THE INTERSOCIETAL
RADIATION EXPOSURES NEW PET-CT SCANNER 3D ECHO VOLUME
NEARLY TRIPLED
0 10,000 20,000 30,000 40,000 50,000 CT DVU Echocardiography Cardiac MR Cardiac PET Cardiac SPECT 2020 2021 2022 PROCEDURE VOLUMES

Pulmonary Vascular Disease

Our Comprehensive Pulmonary Vascular Disease Program offers coordinated, multidisciplinary expertise by a team of specialists in cardiology, pulmonary hypertension, vascular medicine, anticoagulation management, hematology, emergency medicine, hospital medicine, interventional cardiology, interventional radiology, and cardiothoracic surgery. Patients have access to highquality, progressive care across the entire spectrum of disease, including acute and chronic pulmonary embolism (PE), pulmonary hypertension, specifically chronic thromboembolic pulmonary hypertension (CTEPH), and pulmonary veno-occlusive disease.

Patients with a prior history of pulmonary embolism who present with shortness of breath, fatigue, or right heart failure should undergo a ventilation perfusion scan (VQ) and echocardiogram to evaluate for chronic PE or CTEPH. If positive, patients should be seen at a center of excellence with specific expertise in pulmonary endarterectomy and balloon pulmonary angioplasty (BPA)

We staff a dedicated, multidisciplinary, 24-hour oncall pulmonary vascular disease service available to referring physicians internal and external to U-M Health. This service is a gateway to our pulmonary embolism

response team (PERT) as well as our inpatient and outpatient specialized care teams, providing seamless coordination of medical, interventional, and open surgical management.

The Frankel CVC is a regional referral center for CTEPH, and the only center in Michigan to offer both pulmonary endarterectomy and BPA. To deliver optimally integrated care across health systems, we host monthly virtual care coordination conferences with our statewide referring physician community. Patients who are not eligible for the complex, open-heart endarterectomy procedure are treated with minimally invasive BPA. Our highly trained specialists perform over 30 pulmonary endarterectomies annually and routinely perform pulmonary angiogram and BPA.

The Michigan Pulmonary Angiography and Angioplasty course (Mi-PACE) is offered live quarterly by U-M Health. In addition to didactics, participants are invited to directly observe expert pulmonary angiography and angioplasty. Past participants have successfully launched new chronic pulmonary embolism and CTEPH treatment programs at comprehensive academic medical centers nationwide.

>200 PULMONARY ENDARTERECTOMIES EXPONENTIAL PULMONARY INTERVENTIONAL GROWTH:

>400 COMPLETED PROCEDURES PULMONARY ANGIOGRAPHY AND BPA

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FIRST TO BE ACCREDITED AS A CENTER OF COMPREHENSIVE CARE BY THE PULMONARY HYPERTENSION ASSOCIATION

Preventive Cardiology

The Cardiovascular Disease Prevention and Rehabilitation Program offers comprehensive preventive care and cardiac rehabilitation from a multidisciplinary team including cardiologists, lipidologists, cardiac geneticists, hypertension and vascular specialists, endocrinologists, nurse practitioners, nutritionists, social workers, and exercise physiologists who share a vision for maximizing cardiovascular health for patients. Our physicians are nationally recognized experts in cardiovascular disease prevention.

Preventive cardiology specialists focus on primary and secondary preventive measures, including early detection of cardiovascular disease, risk stratification and individualized, evidence-based treatment strategies to prevent first and recurrent coronary and other vascular diseases, including heart attacks, strokes, and heart failure.

Our lipid management service includes boardcertified lipidologists who specialize in lipid and lipoprotein metabolism and associated disorders and treatment. They are regional experts in diagnosing and treating genetic lipid disorders such as familial hypercholesterolemia, high triglycerides, and abnormally high or low HDL and LDL cholesterol. Qualifying patients have access to the latest breakthrough therapies, such as the twice-yearly, LDL-lowering “cholesterol vaccine” inclisiran which has none of the muscular-related side effects common with statin therapy.

For severe lipid disorders, we are one of only a few centers in the country and the only one in Michigan to offer lipid apheresis, an FDA-approved treatment to lower LDL cholesterol. For patients with extremely high

cholesterol levels (LDL cholesterol greater than 400mg/ dl), we offer a novel intravenous medication given monthly. In a holistic approach unique to the Frankel CVC, all referred patients see a nutritionist prior to the first visit with a lipid specialist to begin dietary modifications.

Our Comprehensive Hypertension Center, designated as such by the American Society of Hypertension, is expert at diagnosing and controlling both common and rare forms of hypertension, including resistant and refractory hypertension. The team includes hypertension experts in cardiology, endocrinology, vascular medicine, interventional radiology, and vascular and endocrine surgery.

A multidisciplinary team of cardiometabolic specialists helps patients manage and reverse components of metabolic syndrome, including pre-diabetes, hypertension, central obesity, elevated triglycerides, low HDL cholesterol, and fatty liver disease. Through lifestyle changes implemented in our structured home and centerbased MetFit program, patients are able to reduce their risk of cardiovascular disease, prevent or delay onset of diabetes and chronic liver disease, and reduce the consequences of obesity.

Our nationally recognized cardiac rehabilitation program provides center-based and hybrid center- and home-based medically monitored exercise under the supervision of board-certified exercise physiologists. Following comprehensive evaluation and testing, patients are given an individualized exercise prescription and are supported by a robust lifestyle modification educational program from Frankel CVC experts in nutrition, psychological distress, and fitness.

PATIENTS BECOME A SUPPORT GROUP IMPROVING OUTCOMES

M-LINE: 800-962-3555 DIFFERENTIATORS IN CARDIOVASCULAR CARE n 15
ONE OF FEW PREVENTIVE CARDIOLOGY PROGRAMS WITH GROUP ORIENTATION LED BY EXERCISE PHYSIOLOGISTS
16 n FRANKEL CARDIOVASCULAR CENTER UMCVC.ORG

Areas of Excellence

Frankel CVC specialists in all areas of cardiovascular care work collaboratively across U-M Health and the greater medical community to provide the most advanced treatment options for patients. Here are a few more of the many innovative services we offer. For every one of our programs, our goal is to interact closely with referring physicians as we provide specialty treatment options and services for your patients, with a seamless transition back to your care.

ADULT CONGENITAL HEART DISEASE

The Adult Congenital Heart Disease (ACHD) Program is accredited as a Comprehensive Care Center by the Adult Congenital Heart Association — the first program in Michigan to earn this distinction. Accreditation recognizes the program as a leader in the field and a provider of the highest quality care for ACHD patients.

Our dedicated team includes three adult congenital cardiologists, with over 30 years of combined clinical expertise, coupled with specially trained advanced practice providers and nurse clinicians. The ACHD team partners with specialists in congenital heart imaging, electrophysiology, minimally invasive catheterization, and cardiothoracic congenital surgery to ensure seamless, wrap-around care. We are highly experienced in transcatheter pulmonary valve replacement, and able to offer multiple options for the treatment of severe pulmonary valve regurgitation. Our program also works closely with the U-M Health cardio-obstetrics program to care for pregnant women with congenital heart disease.

Our program is one of few across the country to offer an ACGME-accredited University of Michigan Adult Congenital Heart Disease Fellowship to train the next generation of board-certified ACHD specialists. The twoyear fellowship program is a collaboration between the Frankel CVC and the C.S. Mott Children’s Hospital.

FRANKEL CVC ACHD PROGRAM COVERS THE STATE OF MICHIGAN

WITH LOCATIONS IN ANN ARBOR, KALAMAZOO, LANSING, MARQUETTE, PETOSKEY, TRAVERSE CITY, AND GRAND RAPIDS

M-LINE: 800-962-3555 DIFFERENTIATORS IN CARDIOVASCULAR CARE n 17 KEY SERVICE

CARDIAC ANESTHESIA

At the Frankel CVC, cardiac anesthesiologists provide care in procedural areas and the intensive care unit. Our fellowship-trained cardiac anesthesiologists with board certification in perioperative echocardiography are a vital part of the team for all interventional and surgical procedures. With the highest degree of training and expertise in critical care anesthesiology, the team of intensivists provides 24-hour in-house coverage in the cardiovascular surgical ICU.

Cardiac anesthesiologists provide care for complex cardiac, vascular, and thoracic surgical cases as well as structural heart procedures. The team collaborates with the echocardiography lab, providing anesthesia and imaging care for patients undergoing transesophageal echocardiograms, and the cardio-obstetrics clinic, leading anesthesia planning for delivery.

Members of the Frankel CVC anesthesiology program lead statewide quality improvement efforts as members of the Multi-center Perioperative Outcomes Group (MPOG) and its peer-review subgroup ASPIRE, a BCBS of Michigan Collaborative Quality Initiative.

CARDIO-OBSTETRICS

The Cardio-Obstetrics Program is a leading referral center, caring for high-risk patients throughout Michigan. The program combines the expertise of cardiologists, maternal-fetal medicine specialists, and anesthesiologists to provide wrap-around care to achieve optimal birth outcomes.

The team specializes in the full spectrum of cardiovascular conditions and partners with patients and referring providers to create personalized plans for care during pregnancy, labor, and birth, and during the postpartum period. With a Level III NICU, expertise in adult congenital heart disease, and a combined clinical space for both obstetrics and cardiology appointments, the Frankel CVC delivers top-tier care for the entire spectrum of heart disease to mothers and babies. We offer pre-conception and contraception counseling for patients who want to understand the risks associated with pregnancy, as well as a remote, virtual blood pressure monitoring program for patients with hypertensive disorders of pregnancy before and after birth.

We also treat mothers who develop heart disease during pregnancy, including peripartum cardiomyopathy and preeclampsia.

18 n FRANKEL CARDIOVASCULAR CENTER UMCVC.ORG

CARDIO-ONCOLOGY

The Frankel CVC’s Cardio-Oncology Clinic is one of only a few in Michigan, and was one of the first in the country to provide comprehensive, coordinated care for cancer patients and cancer survivors. Our team of cardiologists and oncologists work together to optimize patients’ pre-existing heart disease and minimize risk from cancer therapy. We have expertise in the full spectrum of heart and vascular complications related to cancer treatment, including cardiac amyloidosis, carcinoid heart disease, cardiac tumors, and all forms of cardiotoxicity arising from cancer therapeutics. Our goal is to improve the quality of life for cancer patients and eliminate barriers to effective treatment as we support them from diagnosis through survivorship and monitor for late effects.

Our clinic is specially recognized for our pre-bone marrow transplant cardiovascular evaluation, ensuring the safety of patients about to undergo therapy. We also have rare expertise in the management of immune-checkpoint inhibitor myocarditis and nationally are one of a limited number of sites participating in the ATRIUM trial.

Our specialists are at the forefront of translational and clinical research and are studying the most effective ways to prevent and predict cardiotoxicity.

Cancer patients suspected of having symptoms related to cardiac issues or those with abnormal cardiac imaging should be seen by an experienced subspecialty team for evaluation.

GENETIC COUNSELING AND TESTING

The Genetic Counseling and Testing Program is the only program in the state with a dedicated cardiovascular genetics team offering genetic counseling and testing for individuals diagnosed with inherited cardiovascular conditions and their families. Our counselors are available to see adult patients at the Frankel CVC and pediatric patients at the C. S. Mott Children’s Hospital. The program works hand-in-hand with a multidisciplinary team of specialists in cardiomyopathy, arrhythmia, aortic disease, heart failure, early-onset coronary artery disease, pulmonary arterial hypertension and other vascular/ arterial diseases.

As leaders in clinical research, we are working to translate our findings into useful clinical information for patients and their families. Our board-certified genetic counselors are available to assist clinicians and to prepare individuals with familial cardiovascular disease for genetic testing, including how testing might impact the patient and family.

Any individual with a family of heart disease — in particular, early-onset heart disease — is encouraged to meet with a genetic counselor experienced in inherited cardiovascular conditions.

M-LINE: 800-962-3555 DIFFERENTIATORS IN CARDIOVASCULAR CARE n 19

INHERITED CARDIOMYOPATHIES

The Inherited Cardiomyopathies Program specializes in the treatment of all inherited heart muscle conditions. As the only site in Michigan participating in all currently ongoing clinical trials for both obstructive and non-obstructive hypertrophic cardiomyopathy (the most common form of cardiomyopathy), our specialists have been at the forefront of practice-changing advances for managing the disease and developing new drugs that delay its progression

Our multidisciplinary team includes cardiologists, electrophysiologists, and advanced heart failure specialists (both adult and pediatric), genetic counselors,

cardiac surgeons, cardiac imaging specialists, exercise physiologists, nutritionists, nurses and advanced practice providers. This approach allows seamless transition of care from pediatric to adult stages and efficient, patientcentered communication.

Our specialists encourage timely referral to a center of excellence to identify and monitor inherited heart conditions in early stages to optimize outcomes.

RECOGNIZED AS A CENTER OF EXCELLENCE SINCE 2007

CARDIOVASCULAR NURSING

The Frankel CVC nursing team is dedicated to delivering compassionate care, evidencebased practice, and clinical expertise based on the unique needs of every patient served.

U-M Health nurses have achieved Magnet designation for two consecutive cycles, a prestigious distinction that recognizes health care organizations for quality patient care and outcomes, nursing excellence, and innovation in professional nursing practice. Several of our nursing units have earned the Beacon Award for Excellence, recognizing caregivers whose systematic approach to evidence-based care optimizes patient outcomes. Many Frankel CVC nurses have been honored with the Daisy Award which recognizes extraordinary nurses who exemplify excellence through compassionate and persistent patient advocacy and consistent adherence to the highest clinical and ethical standards of the nursing profession.

With the launch of the new RN Answer Line call center, patients have access to expedited care and are triaged by a nurse for immediate symptom management. Virtual platforms such as MPOTA (MiChart Patient Outreach Texting Application) and Conversa, a mobile appbased virtual care and triage platform, keep patients connected to our nurses electronically.

Frankel CVC advanced practice nurses practice at the top of their license, both independently and paired with cardiologists through the General Cardiology Advanced Practice Initiative, a program with has increased patient satisfaction, strengthened APP/physician relationships, and improved efficiency in patient care.

MAGNET AWARD OF EXCELLENCE FOR TWO CONSECUTIVE CYCLES SINCE 2007

RECOGNITION FOR

EXCELLENCE

IN EVIDENCE-BASED CARE THAT BENEFITS PATIENTS

RECOGNITION FOR EXCELLENCE IN COMPASSIONATE PATIENT ADVOCACY AND PROFESSIONAL STANDARDS

20 n FRANKEL CARDIOVASCULAR CENTER UMCVC.ORG

PERIPHERAL ARTERY DISEASE

The Peripheral Artery Disease Program is a multidisciplinary team of specialists in interventional cardiology, interventional radiology, cardiovascular medicine and vascular surgery. From mild to the most complex cases, our patientdriven program focuses on improving each individual’s quality of life with the most appropriate treatment plan, developed with a long-term, holistic perspective

Several specialists of our team have participated in the writing group for the national PAD guidelines and participate in the American Heart Association PVD Council and PAD Summit. Specialists take an evidencebased approach to patient care, with recommendations for medical therapy before surgical procedures, when appropriate. Approximately 90% of patients are on guideline-directed medication therapy (aspirin, direct oral anticoagulants, and statins), offered smoking cessation assistance and medications and participation in

a supervised exercise program. Patients can be referred to our local supervised exercise program or given assistance to establish care with external programs.

We seek to follow guideline-based strategies for revascularization using the newest available devices, such as transradial catheters and devices, atherectomy, drug-eluting balloons, and drug-eluting or covered stents. When necessary, patients are treated with a hybrid revascularization approach involving both open surgical and percutaneous revascularization. The PAD program also collaborates with the U-M Health podiatry and wound clinic teams.

Patients have a strong voice in quality of life research at the Frankel CVC. Patient advisors are actively involved in all clinical trials to ensure they are patient-centered. They are also engaged in the Vascular Quality Initiative “My PAD Pilot Study,” a forum for patients to report their experience and a resource for our team to assess outcomes.

MULTIDISCIPLINARY TEAM OF PROVIDERS

REVIEWS CHALLENGING CASES FOR BEST TREATMENT RECOMMENDATIONS

96.1% PATIENT SATISFACTION

SAME DAY DISCHARGE TO HOME FOR ENDOVASCULAR PROCEDURES

QUALITY IN PATIENT CARE

The Frankel CVC is committed to achieving superior, highly reliable patient care. Frankel CVC clinicians have led the Blue Cross Blue Shield Cardiovascular Consortium (BMC2) Percutaneous Coronary Intervention quality improvement initiative since its inception in 1997, making it the longest running value partnership in Michigan

Our clinicians are also integral leaders for all other BCBS cardiovascular collaborative quality initiatives, including:

• BMC2 Vascular Surgery

• Michigan Anticoagulation Quality Improvement Initiative (MAQI2)

• Michigan Society of Thoracic and Cardiovascular Surgeons (MSTCVS) Quality Collaborative

• Michigan Structural Heart Consortium (MISHC)

These CQIs are informed by their associated regional and national registries and create an environment where data transparency facilitates the development of statewide best practices in safety, appropriateness and clinical care quality.

M-LINE: 800-962-3555

DIFFERENTIATORS IN CARDIOVASCULAR CARE n 21

STROKE

The U-M Health Comprehensive Stroke Center provides timely, evidencebased and effective acute stroke management 24/7 as well as secondary stroke prevention and recovery. The multidisciplinary team includes specially trained experts in emergency medicine, neurology, neurosurgery, neuro-interventional radiology, neurocritical care, vascular surgery, cardiology, anesthesiology, internal medicine, and physical medicine and rehabilitation.

The Comprehensive Stroke Center has been a Joint Commission Certified Comprehensive Stroke Center since 2014, and its physicians are active in the development of national guidelines for the treatment of stroke. Frankel CVC faculty lead research across race, ethnic, social and gender health disparities in stroke care, and clinical trials that seek to optimize acute stroke intervention and secondary stroke prevention. U-M Health serves as a Regional Coordinating Center for NIH StrokeNet — a nationwide hospital network conducting leading stroke clinical trials.

The center has earned Comprehensive Stroke Center certification by the American Heart Association and American Stroke Association in collaboration with the Joint Commission and is consistently recognized for High Performance for Stroke by U.S. News & World Report in its annual rankings.

FY22

TRANSITIONS OF CARE

Because a patient’s health is most vulnerable in the short term following discharge, Frankel CVC has a number of follow-up options or Bridge Clinics to help patients stay healthy and reduce their risk of readmission

• Within 14 days post-discharge, patients are seen by an advanced practice provider in one of our Bridge Clinics for a thorough medical assessment. This ensures patients are on the correct medications, have access to the necessary cardiovascular resources, fully understand their role in their own care, and have a follow-up appointment scheduled with their cardiologist.

• General cardiology – Patients on medical management receive a call from a LPN three days post-discharge to reconcile medications and ensure follow-up appointments have been scheduled.

• Heart failure patients receive blood pressure cuffs and scales that enable them to check vital signs, weights and fill out a daily symptom survey on a tablet enabled with cell service. Results are reviewed by an RN seven days a week. Post-acute care physicians and advanced practice providers triage patient concerns, manage acute problems, and coordinate with the patient’s cardiologist or primary care provider for 30 days after hospital discharge.

Our data has shown that patients who participate in Bridge Clinics are less at risk for readmission to the hospital or Emergency Department visits over six months than those who do not participate.

BRIDGE CLINIC PATIENTS OFTEN EXPERIENCE

READMISSION RATES

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LOWER
54 THROMBECTOMY PROCEDURES PERFORMED

VENOUS HEALTH

The Venous Health Program is a multidisciplinary, high-volume clinic that offers expert care for the entire spectrum of venous disease provided by vascular surgeons, interventional radiologists, and vascular medicine specialists.

Our highly trained experts treat patients with conditions ranging from superficial to the most complex venous disease. We offer personalized therapies comprising lifestyle changes, compression, medications, and massage in addition to interventional therapies. With over 30 years of experience, the Frankel CVC is a national tertiary referral site for patients requiring recanalization, reconstruction, or stenting of central vein occlusions

and other complex procedures. Our collaborative multidisciplinary team also provides comprehensive management of pelvic venous disease

Frankel CVC’s diagnostic vascular laboratory provides state-of-the-art noninvasive venous diagnostic studies including DVT scans, venous reflux scans with perforators for patients with venous ulcerations, pelvic ultrasound for patients with pelvic venous disease, venography, and cross-sectional CT and MR imaging.

We strive to provide patient-centered access to our multidisciplinary expertise closer to home through virtual visits, educational programs for our referring physicians, and services available at locations throughout the region.

DIFFERENTIATORS IN CARDIOVASCULAR CARE n 23
M-LINE: 800-962-3555
24 n FRANKEL CARDIOVASCULAR CENTER UMCVC.ORG

Procedural Volumes

M-LINE: 800-962-3555 DIFFERENTIATORS IN CARDIOVASCULAR CARE n 25
PROCEDURE CATEGORY DEFINITION FY2020 FY2021 FY2022 Percutaneous Coronary Intervention Percutaneous Coronary Intervention (PCI) 524 820 751 Transcatheter Valve Disease Total transcatheter valve procedures 335 340 319 Surgical Cardiac Disease (Coronary & Valve) Isolated Aortic Valve Replacement 117 121 149 Isolated Mitral Valve Replacement 98 92 80 Isolated Mitral Valve Repair 162 173 166 Isolated CABG 196 194 220 Isolated AVR + CABG 34 41 47 Isolated MV Replacement + CABG 9 7 12 Isolated MV Repair + CABG 21 19 24 Aortic Disease Vascular Surgery: Open Abdominal Aortic Aneurysm (OAAA) 44 60 42 Vascular Surgery: Abdominal Endovascular Aneurysm Repair (EVAR) 64 72 53 Vascular Surgery: Complex Endovascular 10 18 14 Cardiac Surgery: Thoracic Aortic Aneurysm (TAA) 301 284 306 Cardiac Surgery: Descending/Thoracoabdominal 36 53 37 Cardiac Surgery: Thoracic Endovascular Aneurysm Repair (TEVAR) 76 64 58 Arrhythmia Management Cardiovascular Implantable Electronic Device (CIED) Procedures (PPM, ICD, ILR) 999 1,079 1,148 Ablations 1,109 1,184 1,243 Transcatheter Left Atrial Appendage Occlusion (LAAO) 19 26 59 Surgical Left Atrial Appendage Exclusion 209 220 214 Heart Transplant Heart Transplants 24 49 34 Heart + Kidney Transplants 2 2 3 Heart Failure Right Heart Catheterization (RHC) 670 890 876 Endomyocardial Biopsy 363 356 287 VAD Implants 43 30 31 Re-implants 12 8 3 Venous Health All venous procedures 231 229 226 Stroke Stroke Cases 548 572 531 Vascular Surgery: Carotid Endarterectomy (CEA) Procedures 74 72 54 Vascular Surgery & Neurology: Carotid Artery Stent (CAS) and Transcarotid Artery Revascularization (TCAR) 19 44 35 Chronic Thromboembolic Pulmonary Hypertension (CTEPH) Cardiac Surgery: Pulmonary Endarterectomy 23 26 21 Interventional Cardiology: Balloon Pulmonary Angioplasty (BPA) 22 13 78 Interventional Cardiology: Pulmonary Angiography (PA-Gram) 75 68 97

Research

The Frankel Cardiovascular Center has a vast research enterprise reliant on sound strategy to maximize efficiencies, quality and research opportunities. The commitment to excellence through teamwork, innovation, caring, inclusion and integrity is the basis for success for the Frankel CVC Research Programs. Our goal is to generate new knowledge and make significant advances in cardiovascular research to lead the fight against cardiovascular disease.

Our commitment to basic science, translational and clinical research keeps us at the forefront of scientific discovery, demonstrates our leadership in the fight against cardiovascular disease and ensures patients have access to the expansive range of clinical research studies that are currently enrolling at the Frankel CVC.

There are currently 478 active research studies across 41 diverse divisions, departments, schools, and institutions at the University of Michigan.

RESEARCHERS AND CLINICIANS

The Frankel Cardiovascular Center recruits and retains promising scientists and clinicians who are not only successful in their fields, but who represent the Center’s mission, vision and values. Visit our digital timeline (med.umich.edu/cvc/timeline/) to view the contributions of U-M cardiovascular researchers over the past 100+ years.

FACULTY MEMBERS 359

JOINT APPOINTMENTS 85

DIVISIONS, DEPARTMENTS, SCHOOLS, INSTITUTES 35

26 n FRANKEL CARDIOVASCULAR CENTER UMCVC.ORG

COLLABORATIVE PROGRAMS WITH LASER-FOCUSED RESEARCH GOALS

• M-BoCA* – work in understanding cardiovascular aging

• M-BRISC** – examining biological sex differences and their impact on cardiovascular health

• MI-AORTA – conducting aortic disease research in parallel with the clinical and educational aspects of this program

• MI-REACH – collaborative program in cardiovascular imaging

*Michigan Biology of Cardiovascular Aging Program

**Michigan Biological Research Initiative on Sex Differences in Cardiovascular Disease

RESEARCH EDUCATION OPPORTUNITIES TO DISCUSS AND INSPIRE NEW DISCOVERIES

• Frontiers in Cardiovascular Science –Basic Science content-focused seminar

• Cardiovascular and Cardiovascular Medicine Grand Rounds – Clinical science content-focused seminars

• C3RG* – Research staff education content-focused seminar

• SURF** – Basic science lab experience

• MI-AORTA – Invited Speaker Series and Case Discussions

*Cardiovascular Center Clinical Research Group

**Summer Undergraduate Research Fellowship

***Multidisciplinary Aortic Program

DEDICATED RESOURCES TO FACILITATE RESEARCH SUCCESS

• CHIP*

• FCVC Cores**

• Regeneration Core Lab

• Shared cutting-edge research equipment inventory available to all CVC faculty

• Internal funding opportunities to launch discovery (nearly $10M invested since 2013)

*Cardiovascular Health Improvement Project

**Frankel Cardiovascular Center Core Laboratories

FOR MORE INFORMATION

TECHNOLOGY TRANSFER LEADERS

Licensing agreements for CVC Members – 2007–2021

Please call 1-888-286-4420, email CVCVolunteer@med. umich.edu or visit UMHealthResearch.org for answers to your questions and additional information about our research programs.

Patients and their families can sign up to be matched with research studies for specific health conditions through UMHealthResearch.org, the greater University’s research community website.

M-LINE: 800-962-3555

DIFFERENTIATORS IN CARDIOVASCULAR CARE n 27
FILINGS 99 in FY22 621 ACTIVE 34 in FY22
LICENSED 4 in FY22 63
328
BROAD OFFERING OF CLINICAL TRIAL OPPORTUNITIES Clinical Trials Open to Enrollment Pulmonary Hypertension Arrhythmia Aortic Heart Failure and Cardiomyopathy Other Vascular 3% Structural Heart 8% 10% 14% 14% 18% 33%

One of the main pillars of the Frankel CVC mission is education. Expanding our understanding of cardiovascular disease across the lifespan is a collaborative effort among clinicians, scientists, patients and their families. Our focus on the exploration of improved treatments, disease mechanisms, genetics and myriad other factors impacting patient care supports our educational partnerships with our referring physicians to improve outcomes for all.

CARDIAC SURGERY SIMPLIFIED VIDEO SERIES

View our playlist of videos on YouTube highlighting short segments of cardiac surgical procedures and complex cases. Visit michmed.org/kQGrr

GRAND ROUNDS & WEBINARS

Our Grand Rounds program features a series of talks presented by Frankel CVC faculty, guest faculty and medical students on the topics of Cardiovascular Medicine, Cardiac Surgery and Vascular Surgery. For more information or to register to view live Grand Rounds, email Erika Laszlo at physicianliaisons@med. umich.edu. To view our playlists of webinars, grand rounds and other cardiovascular-related videos, visit umcvc.org/physician-resources.

HEALTH LAB BLOG

Blogs posted at MichiganHealthLab.org are geared toward medical professionals, researchers and thought leaders and feature informative articles about cuttingedge research, medical breakthroughs and related patient profiles.

ONGOING COMMUNICATION

Don’t miss our latest news. Sign up for our newsletter on clinical updates, research and more from the Frankel CVC. Subscribe today at umcvc.org/cardio-news.

CONTINUING EDUCATION

Throughout the year, the U-M Frankel CVC offers physicians, mid-level and advanced practice providers a variety of continuing medical education courses and seminars taught by our faculty. For information on upcoming courses, visit med.umich.edu/ intmed/cme/calendar.htm.

Education
28 n FRANKEL CARDIOVASCULAR CENTER UMCVC.ORG

PATIENT AND FAMILY EDUCATION

The Frankel CVC’s Mardigian Wellness Resource Center provides information about cardiovascular health in patient-friendly language. Our goal is to help patients and families understand their health conditions, make informed decisions and become active members of their health care team. Visit umcvc.org/ mardigianwellness-resource-center

FRANKEL CVC CARDIOVASCULAR CARE GUIDES

Our Cardiovascular Care Guides site is for patients, families, and the general public. The site includes cardiovascular patient education videos, websites and handouts created or approved by our Frankel CVC clinicians. Visit careguides.med.umich.edu

COMMUNITY HEALTH OUTREACH

The Frankel CVC is committed to providing education and services to improve the health and well-being of our surrounding community. The goal of the program is to increase the quality, diversity, availability, and effectiveness of community-based education to prevent cardiovascular disease, improve health, and enhance the quality of life for all. In the past year, events from clothing drives to AED awareness demonstrations were a collaborative effort engaging various groups, organizations, and FCVC faculty/staff, all of whom have made a commitment to stewardship within our community. For more information call 734-232-4120

DIFFERENTIATORS IN CARDIOVASCULAR CARE n 29
M-LINE: 800-962-3555

Your Resources

3 WAYS TO REFER TO THE FRANKEL

CARDIOVASCULAR CENTER

CALL

M-LINE, 800-962-3555

• Admissions/Transfers

• Appointments

• Physician Consultations

• Patient Information FAX

Consult Request Form to 734-232-4480

eREFERRAL uofmhealth.org/provider/ emr-access

Three options:

1. Direct Messaging (non-EPIC EMR to U-M Health)

2. EPIC Care Everywhere to Michigan Medicine

3. Provider Portal

ELECTRONIC IMAGE TRANSFER PROCESS uofmhealth.org/uploadimages

PHYSICIAN LIAISON PROGRAM

Communication with our referring physicians is essential to coordinating patient care. To this end, our Physician Liaison Program offers personalized service to community-based physicians throughout the region.

Erika Laszlo, our Frankel CVC Outreach Manager, provides information about new cardiovascular services, treatment options and clinical trials; assesses your needs and determines how we can best meet them; and shares outreach opportunities from our clinical faculty.

For additional information, call M-LINE at 800-962-3555 or email physicianliaisons@med.umich.edu

M-LINE: 800-962-3555

M-LINE is a 24-hour, toll-free number for our referring physicians and staff seeking access to clinical services and faculty at U-M Health. The M-LINE staff works closely with personnel across U-M Health to provide efficient and personalized service.

To make a referral or speak with one of our specialists, contact M-LINE: 800-962-3555. For additional referral information, visit the U-M Health Provider website: med.umich.edu/umhs/health-providers

30 n FRANKEL CARDIOVASCULAR
UMCVC.ORG
CENTER

DIRECT MESSAGING

EHR-to-EHR Communication

Direct messaging is a secure, standardized way that health care organizations can exchange patient health information and referrals directly between electronic health record (EHR) systems. This functionality allows practices to connect with U-M Health without having to use fax machines or mail services.

Direct messaging can be used to securely send:

• Outpatient referrals

• Physician-to-physician messages

• Continuity of Care documents

• Automatic discharge notices

• Summary of Care documents

• Other patient records and results

For more information, visit uofmhealth.org/provider/ direct-messaging or call M-LINE at 800-962-3555

PROVIDER PORTAL

The Provider Portal is a secure, webbased application that enables referring physicians and their staff to access patient medical information, including:

• Appointment notifications

• Admission notifications

• Emergency Department notes

• Laboratory and radiological test results

• Physician/clinic letters

• OR notes

• Progress notes

• Medication lists

• Problem list

• Allergies

Visit uofmhealth.org/providerportal to download a User and Site Agreement form or call M-LINE at 800-962-3555

SECURE IMAGE TRANSFERS

Secure, electronic patient image transfers can be made from any facility to U-M Health. A one-time upload feature allows hospitals and sites not currently connected to U-M Health to transfer images via LifeIMAGE, a third-party HIPAAcompliant image exchange network. Any site connected to the Internet can send DICOM images to U-M Health. Visit uofmhealth.org/outsideimages for more information.

M-LINE: 800-962-3555

PATIENT ADVOCACY Patient and Family Centered Care (PFCC)

At the heart of the U-M Cardiovascular Center is the belief that providing the ideal care experience stems from a partnership between patients, their families, physicians and staff. CVC has created a Patient and Family Centered Care program as a forum for patients and families to share their personal experiences and partner with the CVC faculty and staff to improve care.

U-M has also established numerous Patient and Family Advisory Councils (PFACs) throughout hospital departments, which are an integral part of our PFCC initiative.

For more information, call 734-232-4617, email cvc-pfcc-program@med.umich.edu or visit umcvc.org/ patient-and-family-centered-care-program

Diversity, Equity and Inclusion (DEI)

DEI is a priority at the Frankel CVC. The FCVC Diversity, Equity, Inclusion and Well-being Steering Committee is a group that aims to educate and lead the FCVC staff, faculty, students, and patients/families on issues concerning diversity, equity, inclusion, and well-being. The Steering Committee was established to design and implement innovative and practical ways to engage and emphasize inclusivity across the FCVC.

Through participation, FCVC staff, faculty, and students not only work to create an inclusive work environment, but also strive to create an inclusive space for our patients/families, and educate the FCVC community about health inequities that directly affect patient health outcomes and their quality of life.

For more information about our program and our commitment to DEI, please visit fcvcdei@med. umich.edu.

DIFFERENTIATORS IN CARDIOVASCULAR CARE n 31

CARDIOVASCULAR NETWORK OF

CVNetworkWMI.org

The Cardiovascular Network of West Michigan is a joint operating agreement that leverages the clinical expertise of three existing heart programs in the region — cardiovascular and open-heart surgery programs at Trinity Health Muskegon and University of Michigan Health-West, the cardiovascular program at Trinity Health Grand Rapids — and the nationally ranked expertise of University of Michigan Health’s Frankel Cardiovascular Center in Ann Arbor.

A WYOMING

University of Michigan Health-West Heart & Vascular, Cardiovascular and Cardiothoracic Surgery

2122 Health Drive SW, Suite 133 Wyoming, MI 49519 616-252-5950

B MUSKEGON

Trinity Health Medical Group Cardiothoracic Surgery

1560 E. Sherman Boulevard, Suite 309 Muskegon, Michigan 49444 231-672-8643

Trinity Health Medical Group Cardiology

1212 E. Sherman Boulevard Muskegon, MI 49444 231-672-3500

C GRAND RAPIDS

Trinity Health Medical Group Cardiovascular 1000 E. Paris SE, Suite 200 Grand Rapids, MI 49546 616-685-3450

Trinity Health Medical Group Cardiovascular 310 Lafayette Avenue SE, Suite 301 Grand Rapids, MI 49503

616-685-7850

A C B 32 n FRANKEL CARDIOVASCULAR CENTER UMCVC.ORG Locations 1 Frankel Cardiovascular Center 1500 E. Medical Center Drive Ann Arbor, MI 48109 2 Domino’s Farms 4000 Ave Maria Drive Lobby A, Suite 1300 Ann Arbor, MI 48106 3 Briarwood Health Associates 325 Briarwood Circle, Building 5 Ann Arbor, MI 48108
Brighton Center for Specialty Care 7500 Challis Road Brighton, MI
Brighton Health Center 8001 Challis Road Brighton, MI
6 Ypsilanti Health Center 200 Arnet St. Ypsilanti, MI 48198 7 Chelsea Health Center 14700 E. Old US 12 Chelsea, MI 48118 8 Chelsea Hospital 775 S. Main Street Chelsea, MI 48118 9 East Ann Arbor Surgery and Medical Procedures Center 4270 Plymouth Road Ann Arbor, MI 48109 10 Northville Health Center 39901 Traditions Drive Northville, MI 48168
West Ann Arbor Health Center 380 Parkland Plaza Ann Arbor, MI 48103
MidMichigan Health Advanced Heart Failure Clinic 4011 Orchard Drive, Suite 1002 Midland, MI
4
48116 5
48116
11
12
48640
WEST MICHIGAN

The Regents of the University of Michigan

Jordan B. Acker

Michael J. Behm

Mark J. Bernstein

Paul W. Brown

Sarah Hubbard

Denise Ilitch

Ron Weiser

Katherine E. White

Santa J. Ono (ex officio)

University of Michigan Health Executive Officers

Marschall S. Runge, M.D., Ph.D.

Executive Vice President for Medical Affairs, Dean

Steven L. Kunkel, Ph.D.

Executive Vice Dean for Research

David C. Miller, M.D., M.P.H.

Executive Vice Dean for Clinical Affairs

Debra F. Weinstein, M.D.

Executive Vice Dean for Academic Affairs

Nondiscrimination Policy Statement

The University of Michigan, as an equal opportunity/ affirmative action employer, complies with all applicable federal and state laws regarding nondiscrimination and affirmative action. The University of Michigan is committed to a policy of equal opportunity for all persons and does not discriminate on the basis of race, color, national origin, age, marital status, sex, sexual orientation, gender identity, gender expression, disability, religion, height, weight, or veteran status in employment, educational programs and activities, and admissions. Inquiries or complaints may be addressed to the Senior Director for Institutional Equity, and Title IX/Section 504/ADA Coordinator, Office for Institutional Equity, 2072 Administrative Services Building, Ann Arbor, Michigan 481091432, 734-763-0235, TTY 734-647-1388, institutional.equity@umich.edu. For other University of Michigan information call 734-764-1817.

© 2023 Regents of the University of Michigan

Frankel Cardiovascular Center

University of Michigan Health

1500 E. Medical Center Drive

Ann Arbor, MI 48109

1 M-LINE: 800-962-3555 DIFFERENTIATORS IN CARDIOVASCULAR CARE 11 10 9 8 6 5 4 3 2 1 CHEL SE A BRIGHTON I-96 M 36 M14 M 12 / Michigan Ave. US 24 / Te le grap h Rd I-94 I-94 I-94 I-75 I-75 M8 M 23 M 23 I27 5 I27 5/ I96 M23B M 52 I-96 I-96 I-696 M 5 M 5 M 102 M10 I-696 I75 M 39 M1 NORTHVILLE YPSIL ANT I DE TROI T ANN ARBOR WEST ANN ARBOR 7 12
umcvc.org 1500 E. Medical Center Drive Ann Arbor, MI 48109
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