Department of Biological Sciences Newsletter // Fall 2020

Page 12

UA ALUM CONTRIBUTING TO COVID-19 TESTING DEVELOPMENT

You may or may not have had a test for

Dr. Carol Duffy, who recently retired

– the NBA. While the target audience of

COVID-19, but if so, it most likely was a

from the department, shared “Annie is one of

SalivaDirectTM is the general population and

test via a nasal swab. The Grubaugh Lab at

the most intelligent, mature, and motivated

not necessarily athletes (with labs currently

Yale University has developed a test that can

students I’ve had the pleasure of working with.

being designated across the country to use

bypass that uncomfortable nasal swab, testing

She is one of those special students I know will

the protocol), Grubaugh found opportunity

for the novel coronavirus via saliva – and UA

go far and I will always remember fondly.”

in working with the NBA to accommodate

alum Annie Watkins is part of that lab group’s

While nasal swabs have been prone to

their need for frequent testing, as this project

efforts. During her undergraduate research

shortages over the last few months, the

had the potential to lead to developing a test

at UA, Annie initially joined the Department

SalivaDirect test developed by Grubaugh and

that could benefit the greater population.

of Biological Sciences intending to study

the Yale team, which received Emergency

Annie’s main role in this project has been

Alzheimer’s, but ended up finding her way

Use Authorization (EUA) from the FDA in

to do much of the asymptomatic validation

to study the connection between Herpes

August, does not require any swab or specific

work through the partnership with the NBA.

Simplex Virus (HSV-1) and Alzheimer’s,

type of collection device, as the sample can

“Between another tech and myself we’ve

which led to an interest in virology and

be collected in any sterile container. “The

tested nearly 3800 saliva samples from NBA

applied, translational research.

ultimate goal of this work is to make testing

players, staff, and vendors since the end of

more accessible and affordable which is, and

June.” A preprint awaiting peer-reviewed

will continue to be, so important.”

publication is now available highlighting

“I almost definitely would not be in the program I currently am without my time at UA, and a good bit of that is due to the

According to the FDA, “Yale intends

the testing platform.Annie is currently a

research and faculty relationships I had in

to provide the SalivaDirect protocol to

2nd-year MPH student in Epidemiology

undergrad. I worked in Carol Duffy’s lab on a

interested laboratories as an ‘open source’

of Microbial Diseases with a concentration

few different HSV-1 projects – that work and

protocol. Because this test does not rely on

in Public Health Modeling at YSPH. Her

the time that I spent with Dr. Duffy and Dr. Yu

any proprietary equipment from Yale and can

current experience in graduate school may be

Wang really helped shape me as a scientist. I

use a variety of commercially available testing

different than what she anticipated a year ago

can’t speak highly enough of them as mentors.

components, it can be assembled and used in

“…but I’ve been so glad to be a part of it and

I also very much enjoyed Dr. Olson’s micro

high-complexity labs throughout the country.”

to work with this team to do what we can to

and pathogenic micro classes that further confirmed my interests in infectious diseases.”

12

This testing method was developed thanks to some funding from an unusual source

make a difference in these crazy times.” ■


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