THE
VOLUME LXXX, ISSUE 49
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tuftsdaily.com
Tuesday, December 1, 2020
Tufts partners with local restaurants, Uber Eats for Thanksgiving meals by Peri Barest Staff Writer
Tufts partnered with local restaurants and Uber Eats to provide students with free meals over Thanksgiving break. The meal program aimed to support local businesses while ensuring that students would not have to worry about accessing or paying for food. “We wanted to be sure food security was not a concern over this holiday,” Camille Lizarríbar, dean of student affairs, wrote in an email to the Daily. “We wanted students to be able to take a break from what has been a very different and often stressful semester and to enjoy the holiday without concerns about cost.” The week prior, students who were planning to stay on campus during the break filled out a survey about their meal preferences and preferred pickup location. see THANKSGIVING, page 2
ANN MARIE BURKE / THE TUFTS DAILY
The entrance to the Gantcher Center is pictured on Aug. 28.
Medical school, Cummings school professors research viral proteins, COVID-19 infection by Sarah Sandlow News Editor
Marta Gaglia, assistant professor of molecular biology and microbiology in the Graduate School of Biomedical Sciences (GSBS) at the Tufts University School of Medicine, and Jonathan Runstadler, professor and interim chair of the Department of
Infectious Disease and Global Health at Tufts’ Cummings School of Veterinary Medicine, are collaborating to determine how certain viral proteins influence the way a cell is able to sense a viral infection. Gaglia explained that her lab researches how viruses interact with their host and what happens when a virus enters a cell. She
studies how viruses try to change the cell in ways that would benefit the viruses’ replication. Her lab is working to translate the same ideas to the COVID-19 virus. “That’s something that the virus is going to want to do to delay the onset of the immune response so that the virus can keep replicating for a longer time, and that may have a lot of
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The Cummings School is pictured.
implications for the course of the disease in people,” Gaglia said. Gaglia added that with her collaborator at the Cummings School, they are planning on making viruses that lack specific proteins to observe changes in cell behavior following infection. “Our prediction is that the virus is going to replicate less well missing those proteins because the cell is going to be able to respond more quickly to the infection,” Gaglia said. Runstadler, Gaglia’s collaborator in the project, discussed how Gaglia’s understanding of the way in which viral proteins interact with the immune system relates to his experience in working with viruses that have zoonotic potential, or the threat of movement between species. “Part of this project that I’m really interested in is to see if we can learn a bit about mutations in those viral proteins that [Gaglia] is really interested in, how changes in those proteins impact the infectiousness of the [SARS-CoV-2] virus, particularly for humans but also for other animal species,” Runstadler said. Gaglia explained that the lab plans to differentiate cell cultures
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to make cells that resemble epithelial lung tissue. Runstadler added that his interest in understanding the movement of viruses between different hosts, as well as the difference in animal response versus human response, can be applied to developing better COVID-19 treatments and preventing viral spillover. Studying viral factors involved in pathogenesis will help recognize ways that could treat or prevent the viral infection. “Understanding this in the particular context of [SARSCoV-2] will help us understand the same kind of interactions with the other viruses as well,” Runstadler said. “We’ll be more prepared in some ways to both study other viruses or to deal with and know where to direct our research efforts if there’s another pandemic.” Gaglia explained some of the criteria her lab uses when deciding on the protein candidates for study, including how strongly they block the cell’s response to the virus, as well as how much is already known about the protein. see PROTEINS, page 2 NEWS
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