Pleural Mesothelioma
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Pleural Mesothelioma (ICD‐O C38.4) Rules for Classification The classification applies only to malignant mesothelioma of the pleura. There should be histological confirmation of the disease. Changes in this edition from the seventh edition are based upon recommendations from the International Association for the Study of Lung Cancer (IASLC) Staging Project. The following are the procedures for assessing T, N, and M categories: T categories Physical examination, imaging, endoscopy, and/or surgical exploration N categories Physical examination, imaging, endoscopy, and/or surgical exploration M categories Physical examination, imaging, and/or surgical exploration
Regional Lymph Nodes The regional lymph nodes are the intrathoracic, internal mammary, scalene, and supraclavicular nodes.
TNM Clinical Classification T – Primary Tumour
T1 Tumour involves ipsilateral parietal or visceral pleura only, with or without involvement of visceral, mediastinal or diaphragmatic pleura. T2 Tumour involves the ipsilateral pleura (parietal or visceral pleura), with at least one of the following: ▪▪ invasion of diaphragmatic muscle ▪▪ invasion of lung parenchyma T3 Tumour involves ipsilateral pleura (parietal or visceral pleura), with at least one of the following: ▪▪ invasion of endothoracic fascia ▪▪ invasion into mediastinal fat ▪▪ solitary focus of tumour invading soft tissues of the chest wall ▪▪ non‐transmural involvement of the pericardium
Lung, Pleural, Thymic
TX Primary tumour cannot be assessed T0 No evidence of primary tumour