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The Gut-Brain Connection to Anxiety, Depression and Chronic Pain By Dr. Greg Fors, DC Board-certified Neurologist Have you ever had a “gut-wrenching experience”? Told someone that you could no longer “stomach the situation”. Have you ever felt “butterflies in your stomach” when you’re anxious? We have intuitively recognized our gut-brain connection. For years now science has recognized the role that the brain plays in creating gastrointestinal disorders such as stress-induced gastric ulcers or chronic diarrhea. However, what is now coming clear is that the communication goes both ways, our G.I. tract talks to our brain! In Neurologist Dr. Perlmutter, MD best-selling book “Brain Maker” he explores the astonishing new research on the gut-brain connection and reveals how the health of your brain is dictated by the health of your gut. How can this be? Vagus Nerve: The Gut-Brain Highway It turns out that our brain and central nervous system and the enteric or G.I. nervous system were created from the same tissue during fetal development. These two nervous systems are intimately connected via the vagus nerve or 10th cranial nerve that runs from our brainstem down into our gastrointestinal tract. Messages to control our digestive system are sent from our brain through the vagus nerve to our digestive organs. But what’s coming clear is that messages are now being sent back from our digestive tract through the vagus nerve to our brain. Even more surprising is that the vagus nerve is the route our gut and gut bacteria use to transmit information to our brain. Yes, the health of your G.I. tract and the bacteria in your gut are talking to your brain, and they are sending good messages and bad messages. Some of the bacteria in your gut can release neurotransmitters just like your brain releases, such as serotonin, dopamine and GABA. Therefore, the gut bacteria can speak to your brain in its own language via this vagus nerve. Research has now shown that your gut bacteria can directly impact your mental health through these gut-released neurotransmitters leading to issues with anxiety and depression. The Role of Good Bugs and Bad Bugs Pathogenic or bad bugs in your gut can cause the immune system in your G.I. tract to release, locally and throughout your body, inflammatory cytokine messengers that ramp up inflammation in your body and brain. Gut pathogens can even trigger a systemic stress response (just as if your boss was yelling at you or a tiger chasing you). Also, certain unfavorable bacteria can release substances in the gut that will make you more sensitive to pain. This directly impacts those suffering with chronic pain and fibromyalgia. Having the right type of commensal bacteria in high enough numbers, such as various species of Bifidobacterium and a Lactobacillus, can keep these bad bugs at bay. Even more interesting is that these beneficial bacteria can interact with your immune system in ways that turn off your inflammation and your chronic stress response, thereby reducing your pain and anxiety. Therefore, it’s vital to have “the right stuff” in your gut microbiota. A study recently conducted at UCLA found that women who consumed beneficial probiotics exhibited improved mood and cognition function on MRI, in both the resting state and in performing emotional recognition tasks. An imbalance or overgrowth of gut bacteria, known as dysbiosis in the colon and SIBO in the small intestine, are many times overlooked in a conventional approach to chronic health disorders. This gastrointestinal dysbiosis or SIBO is best understood as “an overabundance of non-acute noninfectious GI microorganisms, adversely affecting the human host”. If you have chronic pain, anxiety or depression and dysbiosis or SIBO has not been found, it may be that no one has been looking for it! I have personally seen it time and time again with patients who tell me that they never felt depressed or anxious until they started experiencing problems with their gut or developed chronic pain or fibromyalgia sometime after the onset of G.I. health issues. How Do You Know If It’s Playing A Role? Within Functional Medicine there are many laboratory tests that can be utilized to check out the health of your gut and see if it’s affecting your brain health. For example, a Comprehensive Digestive Stool Analysis that maps out your “Good And Bad Bugs” (your gut microbiome) through DNA analysis. It also measures Calprotectin that checks inflammation levels in your intestines and Zonulin levels for “leaky gut” along with multiple other measurements of gut health. I also utilize a breath test that is the gold standard test for the presence of SIBO. Do you have chronic pain, anxiety, depression? There may be a gut-brain connection that has been overlooked. Tired of chasing symptoms, of taking drugs with all their side effects of not getting to the underlying causes of your health problems? If you answered yes, it is vital that you attend one of my FREE upcoming seminars on “The Gut-Brain Connection to Anxiety, Depression and Chronic Pain”. Join me, Dr. Greg Fors, on Monday, November 18th or Wednesday, November 20th at the Pain and Brain Healing Center in Blaine, MN. I will discuss how you can reinvent your life, naturally. For directions and to reserve your space, seating is limited, call my clinic at 763-862-7100, you can also schedule a free consultation with me. Dr. Greg Fors, D.C. is a Board-certified Chiropractic Neurologist (DIBCN). As the clinic director of the Pain and Brain Healing Center in Blaine Minnesota he specializes in a functional medicine approach to fibromyalgia, fatigue, food allergies, hypothyroidism, depression, anxiety and insomnia. If you have any questions or comments regarding this article you can contact Dr. Fors at 763-862-7100 He is a sought-after international lecturer for various post graduate departments and state associations. Dr. Fors is the author of the highly acclaimed book, “Why We Hurt” available through booksellers everywhere.

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