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S U N D AY, J A N U A RY 2 2 , 2 0 1 2

Sleep Bet ter in 2012

We catch some zzz’s with Dr. Oz © PARADE Publications 2011. All rights reserved.

Personality Walter Scott,s

WALTER SCOTT ASKS …

Jessica Alba

The latest venture from the 30-year-old actress and mother of two is the eco-friendly, Web-based baby products firm the Honest Company (honest.com).

P Shorty Rossi

Q: Shorty Rossi from

Animal Planet’s Pit Boss spent some time in prison.

How did he survive such a tough environment as a little person? —A. N., West Hollywood, Calif.

A: “It was like a neigh-

borhood reunion,” says Rossi, 42, who opens up about his rough childhood and days as a gang member (he served more than 10 years for attempted murder) in his memoir, Four Feet Tall & Rising, out now. “If I was a kid from Beverly Hills, I would have had issues, but I grew up with half the people in there.” Read more from him (including what he thinks of Michael Vick!) at Parade.com/rossi.

Where did the idea for the Honest Company come from?

I did research when I was pregnant with my first daughter and was horrified by the chemicals in products, even those meant for babies. I would have to go to 50 different places just to get my house and my kid clean. I thought moms needed one place that curated safe items that are affordable and stylish.

Email your questions to Walter Scott at Parade.com /contact

Has motherhood changed the way you view your career? Work takes a

backseat. Before, I’d have two weeks off around Christmas, but I never really did birthdays, or I’d be working in a country that didn’t celebrate certain holidays. Now it’s about family and capturing those moments. When I do work, it’s fun and I take some risks.

ended his run on SVU last year after 12 seasons, returns to TV this summer as a regular on the HBO series True Blood.

He’ll play what executive producer Alan Ball has called “an ancient, powerful vampire who holds the fate [of the show’s two leading men] in his hands.” As for big-screen projects, Meloni plays a general in the Superman reboot Man of Steel, due summer 2013.

Are you still feeling pressure to be a sex symbol?

That’s how I was marketed; I never put much effort into it. I don’t really care. I never did.

Does being 30 feel different? Oh yeah, I am way more secure than I was in my 20s.

P Silverstone, left, and Tyler

Is Donald Trump’s hair real?

—Linda Simon, Las Vegas

Yes, according to the tycoon himself.

“It may not be pretty, but it is mine,” Trump, 65, has said. In a recent attempt to prove naysayers wrong, he let Barbara Walters tug his coif on TV. And how does he maintain his awesome mane? He told Rolling Stone that he washes with Head & Shoulders, air-drys, then combs.

Q: Are Alicia Silverstone and Liv Tyler half-sisters?

Letters to Walter Scott can be sent to P.O. Box 5001, Grand Central Station, New York, N.Y. 10163-5001

—Betty Luster, Edmond, Okla.

A: Though both Silver-

stone, 35, and Tyler, 34, have half-siblings, they are not related to each other. They did, however,

appear as best friends in the risqué music video for 1993’s “Crazy” by Aerosmith, the band fronted by Liv’s father, Steven Tyler.

★ PRESENTS ★

P Chris Meloni

“I failed so many times, I have a

Q: What are Chris Meloni’s plans now that he’s left Law & Order: Special Victims Unit?

—Mary Kessler, Corning, N.Y.

A: The actor, 50, who

GEORGE CLOONEY | ROBERT DOWNEY JR.

<

<

Who Said It?

Alba with her younger daughter, Haven, in October

much better understanding of this journey. It’s how you handle the down part [that counts].”

See the answer at wonderwall.com/whosaidit

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PARADE

2 • January 22, 2012

© PARADE Publications 2011. All rights reserved.

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© PARADE Publications 2011. All rights reserved.

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4 • January 22, 2012

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Š PARADE Publications 2011. All rights reserved.

Sunday with ... all doingg our own thing. Jimmy’s never called me personne ally, only his producers. al He might be a little harder to turn down.

Dustin Diamond (Screech) wrote an unflattering tell-all in 2009.

Dare I ask if you’ve read it?

Last summer, Justin Bieber was on a red carpet wearing a T-shirt with your picture on it. Did you get a deluge of nasty messages

from jealous Beliebers?

Not that I could see on my Twitter page or Facebook. Believe me, girls, he’s way too young for me, so don’t worry! [laughs] I’ve never met him, but I do understand to a degree what his life is like right now, as a recognizable teen star.

What was it like being in Woody Allen’s Hollywood Ending?

Tiffani Thiessen The actress opens up about Justin, Woody, and that Saved by the Bell reunion

PARADE How is having a hit series different this time around?

I’m in more of a supporting role, which is nice right now, as a mom.

And being older, I appreciate it more. I don’t think you understand what a job really is when you’re a teenager.

You used to be billed as TiffaniAmber Thiessen. Why did you drop Amber from your name?

My agent at the time thought it would help distinguish me from [my teen roles]. It’s funny—in elementary school, I went by Amber. I never liked Tiffani.

Jimmy Fallon’s tried to reunite the Saved by the Bell cast for a couple of years. Will it ever happen?

It’s not something I want or need to do, and a few of us feel the same way. We’re

You can ask, but the answer’s no. [laughs] My time is very precious these days, and that’s not how I want to spend it.

The star shares her recipe for kale chips at Parade.com/thiessen

Definitely a top 10 awesome moment of my life. He’s very quiet but knows exactly what he wants.

And he’s kind of nervous with girls. At least he was with me.

Is there anything you are particularly bad at?

“THERE WAS A SIDE OF ME GROWING UP THAT WAS VERY TOMBOY— SKATEBOARDS AND BIKES.”

I can’t whistle. My husband makes fun of me for that.

How do you spend your Sundays?

It’s my favorite day— productive but also kind of lazy. We’re up at 6 or 6:30 because our little one’s an early riser. We go to the park, then to the farmers’ market to get fruits and vegetables. Harper’s favorite is pears, and I’m a kale lover.

Has motherhood changed you?

I’ve let a lot of my type A personality go. When you have a kid, the messiness doesn’t matter anymore.

What would you say if Harper wanted to act in a few years?

In a few years? “No.” [laughs] The business is ever-changing, and I don’t think it’s easy for any kid. Thank God I [survived]. Not every story is that way.

PHOTOS, FROM TOP: HENRY S. DZIEKAN III/GETTY IMAGES; NIGEL PARRY/USA NETWORK; ISTOCKPHOTO. ILLUSTRATION, OPPOSITE: GRAFILU

S

he was a teen dream thanks to Saved by the Bell and Beverly Hills, 90210. Now, at 37, Tiffani Thiessen—mom to 19-month-old Harper, her daughter with actor-artist husband Brady Smith—considers her past a reason to look forward.

“It’ll be interesting when Harper wants to see those shows—and laugh,” she says. It was Thiessen’s idea to make her character on her current series, White Collar (USA, Tuesdays, 10 p.m. ET), an event planner. “I’ve always said that if the acting thing were ever to stop,” she tells Shawna Malcom, “that’s probably what I’d do for a living.”

6 • January 22, 2012

© PARADE Publications 2011. All rights reserved.

Ask Marilyn

By Marilyn vos Savant

When a reader wrote about randomly selecting 100 out of 400 employees each quarter for drug testing, he asked about the chances of an individual being chosen over the course of a year. You answered a different question: “If an individual has not been selected over the first three quarters, what are the chances that he or she will be chosen in the fourth quarter?” The answer to the latter question is indeed 25 percent, as you wrote, but the answer to the former is about 68 percent.

—George Land, Tyler, Tex.

January 22, 2012 • 7

TONIGHT’S DINNER, WRAPPED UP IN MINUTES. Easy Chicken & Cheese Enchiladas Prep: 15 min. Bake: 40 min. Makes: 6 servings

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1. Heat oven to 350°F. Stir soup, sour cream, picante sauce and chili powder in medium bowl.

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Top with tomato and onion. © 2011 CSC Brands LP

You’re right, and I apologize for the mistake. My neurons must have been napping.

The reasoning works this way: Of the 400 names, 25 percent (100) are selected in the first quarter. Assume “perfect” randomization for the purpose of calculation: Of the 300 that weren’t chosen, 25 percent (75) would be selected in the second quarter. Of the 225 still-unchosen names, 25 percent (about 56) would be selected in the third. And of the 169 remaining unchosen names, 25 percent (about 42) would be selected in the fourth.

So a total of 273 different people (100 + 75 + 56 + 42 = 273) will have been selected— about 68 percent of all the employees. (Many names will have been chosen more than once, so 400 tests are still administered.) Yet the chance of any individual’s name being chosen in the next random selection (or in any future selection) never rises above 25 percent.

®

It’s amazing what soup can do. © PARADE Publications 2011. All rights reserved.

A NEW BEDTIME STORY ONCE UPON A TIME, YOU COULD SLEEP LIKE A BABY. NOW YOU’D BE LUCKY TO GET A FULL EIGHT HOURS OF PEACEFUL, UNINTERRUPTED SLUMBER. HERE’S HOW TO REST EASY AGAIN. COVER AND OPENING PHOTOGRAPH BY ALESSANDRA PETLIN OPENING ILLUSTRATION

BY DANIEL PELAVIN

A

s a father of four, a surgeon, and a talk show host, I know all about sleepless nights. More than 25 years ago, when I was a surgical resident, I conditioned myself to get by on just two or three hours of sleep a night.

I can recall walking down an empty hospital

corridor after a long shift and seeing the sun rising silently over the city. I often had trouble drifting off when I got home—and continued to have insomnia even after my residency ended.

I wasn’t alone. Nearly half of all Americans have occasional insomnia, whether because of stress, hormonal changes, or poor bedtime habits; about 15 percent are plagued by chronic sleeplessness.

HAIR, ANNE SOMPANGA; MAKEUP, LINDA MELO; STYLING, JESPER GUDDBERGSEN; PAJAMAS, HANRO (COVER AND INSIDE)

BY DR. MEHMET OZ

8 • January 22, 2012

© PARADE Publications 2011. All rights reserved.

YOU SNOOZE, YOU WIN!

PHOTO CREDITS WILL GO HERE AS SHOWN

Tune in to The Dr. Oz Show this week for more sleep tips, and go to doctoroz.com to register for Dr. Oz’s Transformation Nation: Million Dollar You and pledge to make an earlier bedtime a priority.

Visit us at PARADE.COM

Month 00, 2011 • 00

© PARADE Publications 2011. All rights reserved.

And that’s a problem. Waking up exhausted doesn’t just take a toll on your mood and your performance at work; inadequate sleep can lead to serious health problems—including obesity, cancer, and heart disease— and shortened life expectancy. While you’re sleeping, your body rejuvenates the connections between brain cells, renews its immune function, improves the response to insulin, and secretes growth hormone, which is essential for healthy skin and muscles. People who sleep fewer than six hours a night have a 50 percent higher risk of viral infections and an elevated risk of heart disease and stroke. A new study even suggests that a lack of sleep heightens your risk of Alzheimer’s.

That said, insomnia isn’t something to lose sleep over; plenty of simple strategies can help you get the rest you need. I’ve put together this four-week plan to ensure you sleep better and longer, starting tonight.

WEEK

1

ASSESS YOUR BEDROOM

Dim the lights. Insomnia feeds off the

minor details of modern life, like the soft blue glow from a TV, a computer, a cell phone, a PDA, or even the digital clock on your nightstand. That blue light suppresses the secretion of melatonin, a sleep-promoting hormone. Crack open a book rather than watching reruns just before bed, and cover up blue displays you can’t shut off. Place an orange lightbulb (available at Home Depot or other home improvement stores) in your bedside lamp; its glow lets you read or relax without actively inhibiting melatonin.

Go mattress shopping. As anyone who’s ever been up coughing, wheezing, or blowing his nose can attest, asthma and allergies can significantly affect the quality of your sleep. And one very common cause of both conditions could be living in your mattress. Dust mites are microscopic arachnids that feed on human skin and are a major trigger for asthma and allergies. These bugs like to make their home in beds because of the steady

SLEEP BY THE NUMBERS

95 PERCENT

OF AMERICANS AGES 13 TO 64 SAY THEY USE AN ELECTRONIC DEVICE WITHIN AN HOUR OF BEDTIME AT LEAST A FEW NIGHTS A WEEK

THIS IS YOUR BODY ON INSOMNIA Sleeplessness can have wide-reaching effects on the body. Here’s what happens to …

YOUR BRAIN A new study shows that sleep is necessary to rejuvenate the connections between brain cells; these connections become increasingly erratic the longer you’re awake. According to researchers, the most easily disrupted connections were those essential for memory, executive functioning, and attention.

YOUR MUSCLES The body produces growth hormone during sleep, a function necessary for building and maintaining healthy muscle tissue. So over time, insomnia can zap strength.

YOUR IMMUNE SYSTEM Sleep deprivation

lessens white blood cell activity, which ups the risk of getting sick. In turn, a healthy immune system promotes deep sleep, so long bouts of insomnia can create a vicious cycle.

YOUR BLOOD SUGAR

Insomnia interferes with the body’s ability to metabolize glucose, leading to early signs of diabetes. One study showed that regularly snoozing less than six hours a night makes you 4.5 times more likely to develop prediabetes.

YOUR MOOD Sleepless nights don’t just make you irritable; new research shows that people who suffer from chronic insomnia are five times more likely to become depressed and 20 times more likely to develop panic disorder.

SLEEP BY THE NUMBERS

37 PERCENT

OF AMERICAN ADULTS SAY THEY NEED AT LEAST EIGHT HOURS OF SLEEP TO FUNCTION AT THEIR BEST supply of food; the older the mattress, the more likely that mites have taken up residence. If yours is more than five to seven years old, it may be time for an upgrade. (If your mattress is newer than that, consider buying a mite-resistant casing instead.)

Chill out. Keeping your body cool slows down all of the metabolic processes, including the mental whirring that prevents you from drifting off. The worse your insomnia, the colder your bedroom should be. Start at 68 degrees Fahrenheit and crank it down to 65 degrees (or even as low as 60 degrees) if you still can’t get any rest.

CREATE A BETTER BEDTIME ROUTINE Don’t go to bed hungry. You may think you’re doing your waistline a favor by skipping dinner or not eating after 6 p.m. when your bedtime is midnight, but a growling, empty stomach makes it harder to fall asleep, and that can derail your diet. Researchers at the University of Chicago withheld sleep from study participants and found the lack of shuteye altered appetite-regulating hormones. The subjects reported feeling hungrier, with strong cravings for calorie-dense, carb-rich foods, such as sweets, salty snacks like potato chips, and starchy foods like pasta.

Put a cap on your nightcap. Surveys show that up to 19 percent of people use alcohol to help nod off at night. But after the initial tranquilizing buzz wears off, alcohol often results in more fitful sleep. As your body withdraws from the drug, you may experience symptoms such as waking up in the middle of the night or the inability to reach a deep sleep. A better pre-bed beverage: chamomile tea, which research shows may have a calming effect.

Slip on some socks. Feet often feel colder than the rest of the body because they have the poorest circulation.

A study published in the American Journal of Physiology in 2000 suggests that wearing socks to bed keeps the blood vessels in your feet dilated, drawing blood away from your core and cooling you off, which initiates sleep.

WEEK

2

10 • January 22, 2012

© PARADE Publications 2011. All rights reserved.

WEEK

3

INSOMNIA-PROOF YOUR LIFESTYLE Don’t just lie there. If you suffer through hours

counting sheep, you may soon come to associate your bed with the stress of insomnia. In fact, studies show that spending less time between the sheets—a technique known as sleep restriction—may promote more restful snoozing and, with time, help make your bed a welcome sight at the end of a long day. Calculate the number of hours you actually spend asleep, and then limit your time in bed to no more than that amount. Start with a routine that gets you up at the same time every morning—even if it’s quite early, and even on the weekends.

Once you’re falling asleep more easily at night, you can slowly push your wake-up time forward.

Time your workouts right. Combined with a regular bedtime routine, exercising four times a week may increase your overall sleep time by 1.25 hours each night, according to a recent study published in the journal Sleep Medicine. Why is working out so effective? Exercising significantly increases your core temperature; as your body returns to its baseline a few

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SLEEP BY THE NUMBERS

6 HOURS, 30 MINUTES

AVERAGE AMOUNT OF TIME AMERICAN ADULTS REPORT SLEEPING EACH NIGHT DURING THE WORKWEEK

hours later, your temperature measurably drops, making it easier to drift off. The best time to work out: late afternoon or early evening (at least two hours before bedtime), so your body temperature begins falling just as you’re getting ready for bed.

Break your smartphone addiction. Constantly checking email or scanning your favorite websites stimulates the brain, preventing you from winding down at night. Some research suggests that simply exposing yourself to wireless signals may interfere with sleep. In a major joint study, researchers in Sweden and at Wayne State University in Michigan found that people subjected to a substantial amount of these signals right before bed reported headaches, more difficulty falling asleep, and less restful slumber. The solution: Keep your cell phone out of reach at night, and try to spend less time on it during the day.

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TAKE CONTROL OF SLEEPROBBING HEALTH CONDITIONS Put your shower massager to good use. A warm bath and a massage can help anyone nod off more easily, but they can be particularly helpful if leg cramps keep you awake. Evidence shows that heat and leg massage can improve the symptoms of restless legs syndrome, a disorder that affects up to 10 percent of the population and is characterized by cramping and an unpleasant urge to move your legs, especially WEEK

4

January 22, 2012 • 11

© PARADE Publications 2011. All rights reserved.

SundayDinner A Dish to Sing About Nick Jonas, back on Broadway in How to Succeed in Business Without Really Trying, loves this hearty reminder of home

“MY MOM MAKES ME A PAN OF THIS WHENEVER SHE FEELS I NEED SOME HOME COOKING.”

Cook’s Tips

P You can make this dish in advance and reheat it, covered, in a 325°F oven until hot.

at night. If symptoms persist, ask your doctor whether you could benefit from taking magnesium, which has been shown to relieve leg cramps, or a prescription medication.

Lose weight. Those extra pounds, particularly around the neck, put you at greater risk for obstructive sleep apnea (OSA), a condition in which the soft palate at continued on page 14

STILL CAN’T SLEEP? Natural and over-the-counter sleep remedies can be surprisingly effective, but like prescription drugs, they carry risks, including dependency.

Consult your doctor before taking any sleep medications.

To find out what’s next for the Jonas Brothers, go to Parade.com/jonas

Chile Cheese Egg Casserole 1 stick (½ cup) butter 10 eggs 2 egg whites ½ cup flour 1 tsp baking powder 2 (8-oz) cans diced green chiles 1 quart (4 cups) cottage cheese ½ cup mascarpone 1 lb shredded Monterey Jack Salt and pepper, to taste

1. Preheat oven to 400°F. 2. Place butter in a 9-by-13-inch baking pan. Place pan in oven until butter is melted. Pour half the butter into a small bowl and set aside.

3. Beat eggs and egg whites lightly in a large bowl.

Stir in flour, baking powder, chiles, all cheeses, salt, and

P Spice things up with a dab of green chile enchilada sauce or your favorite salsa.

pepper. Mix well.

4. Pour egg mixture into baking pan.

Pour reserved butter evenly over the top.

5. Bake for 15 minutes. Reduce heat to 350°F and bake 35 to 40 minutes or until casserole is set.

SERVES: 12 | PER SERVING: 440 calories, 9g carbs,

27g protein, 34g fat, 240mg cholesterol, 730mg sodium, 0g fiber

PA tossed green en salad is a greatt accompaniment nt for this casserole. ole.

Diphenhydramine (for example, Benadryl and Sominex) and doxylamine (for example, Unisom) are common OTC antihistamines that are also marketed as sleep aids. Scientists believe that these drugs cause sedation by blocking the brain’s histamine activity, which is normally involved in arousal and alertness.

Melatonin is a sleep-promoting hormone that’s naturally produced by the body at night.

Available as a supplement, it can help you fall asleep if taken two to three hours before bedtime. Keep in mind that the commonly listed dosage (five milligrams) is more than what most people require; instead, start with one milligram and work up to 2.5 milligrams if necessary.

Research suggests that valerian root may have a sedative-like effect, helping you drift off more quickly and prolonging total sleep time.

Try preparing it in a tea and drinking a cup before bed.

PHOTOS, CLOCKWISE FROM TOP RIGHT: KAT TEUTSCH, FOOD STYLING BY VICTORIA ESCALLE, PROP STYLING BY MEGAN HEDGPETH; ISTOCKPHOTO (3); NOEL VASQUEZ/GETTY IMAGES FOR EXTRA. NUTRITION ANALYSIS/CONSULTING BY JEANINE SHERRY M.S., R.D.

I’ve been living on my own for about a year, and I’m not the most talented chef—I can make a great sandwich, but it’s my brother Joe who’s amazing in the kitchen. So my mom, Denise, makes me this casserole, my favorite meal growing up, whenever she feels I need some home cooking.

I first watched her make this when I was 5, and was apprehensive since I’d never liked cottage cheese—I think it was the texture thing. But as soon as I tried it, the love affair started, and it quickly became breakfast, lunch, and dinner for me. The eggs and cheese are perfectly matched; it’s like an omelette, only thicker.

I have type 1 diabetes, which is managed by insulin delivery, but I still try to go with low-carb options like this. I get really excited when my mom brings it over.

Dr. Oz | from page 11

12 • January 22, 2012

© PARADE Publications 2011. All rights reserved.

Cartoon

The #1 ingredient in soup is broth.

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See your dentist. Snorers may also benefit from a mouth guard—a small plastic device worn during sleep to help prevent the soft palate from collapsing. Even if you don’t have OSA, controlling snoring is important; a recent study showed that snoring more than doubles your risk of developing metabolic syndrome, one of the major predictors of future cardiovascular disease. Interrupted sleep, often a result of loud snoring, increases this risk even further.

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© PARADE Publications 2011. All rights reserved.

Medication Guide JANUVIAÂŽ (jah-NEW-vee-ah) (sitagliptin) Tablets Read this Medication Guide carefully before you start taking JANUVIA and each time you get a reďŹ ll. There may be new information. This information does not take the place of talking with your doctor about your medical condition or your treatment. If you have any questions about JANUVIA, ask your doctor or pharmacist.

What is the most important information I should know about JANUVIA? Serious side effects can happen in people taking JANUVIA, including inďŹ&#x201A;ammation of the pancreas (pancreatitis) which may be severe and lead to death.

Certain medical problems make you more likely to get pancreatitis.

Before you start taking JANUVIA: Tell your doctor if you have ever had E 7(5*9,(;0;0: E :;65,: 05 @6<9 .(33)3(++,9 .(33:;65,: E ( /0:;69@ 6- (3*6/630:4 E /0./ )366+ ;90.3@*,90+, 3,=,3: E 20+5,@ 796)3,4: Stop taking JANUVIA and call your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis.

What is JANUVIA? E JANUVIA is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

E $% 0: 56; -69 7,673, >0;/ ;@7, +0(),;,: E JANUVIA is not for people with diabetic ketoacidosis (increased ketones in your blood or urine).

E If you have had pancreatitis (inďŹ&#x201A;ammation of the pancreas) in the past, it is not known if you have a higher chance of getting pancreatitis while you take JANUVIA. E ; 0: 56; 256>5 0- $% 0: :(-, (5+ ,--,*;0=, >/,5 <:,+ 05 */03+9,5 <5+,9 @,(9: 6- (., Who should not take JANUVIA? Do not take JANUVIA if: E you are allergic to any of the ingredients in JANUVIA. See the end of this Medication Guide for a complete list of ingredients in JANUVIA. Symptoms of a serious allergic reaction to JANUVIA may include: E 9(:/ E 9(0:,+ 9,+ 7(;*/,: 65 @6<9 :205 /0=,: E swelling of the face, lips, tongue, and throat that may cause difďŹ culty in breathing or swallowing What should I tell my doctor before taking JANUVIA? Before you take JANUVIA, tell your doctor if you: E /(=, 69 /(=, /(+ 05C(44(;065 6- @6<9 7(5*9,(: 7(5*9,(;0;0: E /(=, 20+5,@ 796)3,4: E /(=, (5@ 6;/,9 4,+0*(3 *65+0;065: E are pregnant or plan to become pregnant. It is not known if JANUVIA will harm your unborn baby. If you are pregnant, talk with your doctor about the best way to control your blood sugar while you are pregnant.

Pregnancy Registry: If you take JANUVIA at any time during your pregnancy, talk with your doctor about how you can join the JANUVIA pregnancy registry. The purpose of this registry is to collect information about the health of you and your )()@ '6< *(5 ,59633 05 ;/0: 9,.0:;9@ )@ *(3305.

E (9, )9,(:; -,,+05. 69 73(5 ;6 )9,(:; -,,+ ; 0: 56; 256>5 0- $% >033 7(:: 05;6 @6<9 )9,(:; 4032 #(32 >0;/ @6<9 doctor about the best way to feed your baby if you are taking JANUVIA. Tell your doctor about all the medicines you take, 05*3<+05. 79,:*907;065 (5+ 565 79,:*907;065 4,+0*05,: =0;(405: and herbal supplements.

Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist when you get a new medicine.

How should I take JANUVIA? E #(2, $% ;04, ,(*/ +(@ ,?(*;3@ (: @6<9 +6*;69 ;,33: @6< E '6< *(5 ;(2, $% >0;/ 69 >0;/6<; -66+ E Your doctor may do blood tests from time to time to see how well your kidneys are working. Your doctor may change your dose of JANUVIA based on the results of your blood tests.

E Your doctor may tell you to take JANUVIA along with other diabetes medicines. Low blood sugar can happen more often when JANUVIA is taken with certain other diabetes medicines. See â&#x20AC;&#x153;What are the possible side effects of JANUVIA?â&#x20AC;?.

E If you miss a dose, take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of JANUVIA at the same time.

E If you take too much JANUVIA, call your doctor or local Poison Control Center right away.

E When your body is under some types of stress, such as fever, trauma (such as a car accident), infection or surgery, the amount of diabetes medicine that you need may change. Tell your doctor right away if you have any of these conditions and follow your doctorâ&#x20AC;&#x2122;s instructions.

E Check your blood sugar as your doctor tells you to.

E Stay on your prescribed diet and exercise program while taking JANUVIA.

E Talk to your doctor about how to prevent, recognize and manage low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), and problems you have because of your diabetes.

E Your doctor will check your diabetes with regular blood tests, including your blood sugar levels and your /,46.36)05

What are the possible side effects of JANUVIA? Serious side effects have happened in people taking JANUVIA. E See â&#x20AC;&#x153;What is the most important information I should know about JANUVIA?â&#x20AC;?.

E Low blood sugar (hypoglycemia). If you take JANUVIA with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you use JANUVIA. Signs and symptoms of low blood sugar may include: E headache E irritability E drowsiness E hunger E weakness E fast heart beat E dizziness E sweating E confusion E feeling jittery E Serious allergic reactions. If you have any symptoms of a serious allergic reaction, stop taking JANUVIA and call your doctor right away. See â&#x20AC;&#x153;Who should not take JANUVIA?â&#x20AC;?. Your doctor may give you a medicine for your allergic reaction and prescribe a different medicine for your diabetes.

E Kidney problems, sometimes requiring dialysis The most common side effects of JANUVIA include: E upper respiratory infection E stuffy or runny nose and sore throat E headache JANUVIA may have other side effects, including: E stomach upset and diarrhea E swelling of the hands or legs, when JANUVIA is used with rosiglitazone (AvandiaÂŽ). Rosiglitazone is another type of diabetes medicine.

These are not all the possible side effects of JANUVIA. For more information, ask your doctor or pharmacist.

Tell your doctor if you have any side effect that bothers you, is unusual or does not go away.

(33 @6<9 +6*;69 -69 4,+0*(3 (+=0*, ()6<; :0+, ,--,*;: '6< 4(@ 9,769; :0+, ,--,*;: ;6 (;

How should I store JANUVIA? ";69, $% (; F ;6 F F ;6 F Keep JANUVIA and all medicines out of the reach of children.

General information about the use of JANUVIA Medicines are sometimes prescribed for purposes that are not listed in Medication Guides. Do not use JANUVIA for a condition for which it was not prescribed. Do not give JANUVIA to other people, even if they have the same symptoms you have. It may harm them.

This Medication Guide summarizes the most important information about JANUVIA. If you would like to know more information, talk with your doctor. You can ask your doctor or pharmacist for additional information about JANUVIA that is written for health professionals. For more information, go to www.JANUVIA.com 69 *(33

What are the ingredients in JANUVIA? Active ingredient: sitagliptin.

Inactive ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, and sodium stearyl fumarate. The tablet ďŹ lm coating contains the following inactive ingredients: polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, red iron oxide, and yellow iron oxide.

What is type 2 diabetes?

Type 2 diabetes is a condition in which your body does not make enough insulin, and the insulin that your body produces does not work as well as it should. Your body can also make too much sugar. When this happens, sugar (glucose) builds up in the blood. This can lead to serious medical problems.

High blood sugar can be lowered by diet and exercise, and by certain medicines when necessary.

JANUVIAÂŽ is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. AvandiaÂŽ is a registered trademark of GlaxoSmithKline.

67@90./; H ,9*2 "/(97 6/4, 697 ( :<):0+0(9@ 6- Merck & Co., Inc. All rights reserved !,=0:,+ 7903

Manufactured by: Merck Sharp & Dohme (Italia) S.p.A. %0( 4030(

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This Medication Guide has been approved by the U.S. Food and Drug Administration.

DIAB-1017402-0003 12/11

Terms and Conditions s 4HIS VOUCHER IS VALID FOR FREE DAY TRIAL SUPPLY OF *!.56)! s ,IMIT VOUCHER PER PATIENT FOR THE DURATION OF THE PROGRAM s 6ALID FOR TIME USE ONLY &REE TRIAL OFFER IS VALID ONLY FOR UP TO TABLETS OF *!.56)! .O PURCHASE IS NECESSARY 2ElLLS ARE NOT REQUIRED s 4HIS VOUCHER IS NOT TRANSFERABLE .O SUBSTITUTIONS ARE PERMITTED #ANNOT BE COMBINED WITH ANY OTHER FREE TRIAL COUPON DISCOUNT PRESCRIPTION SAVINGS CARD OR OTHER OFFER s This voucher is not insurance. s 9OU MUST BE YEARS OR OLDER TO REDEEM THIS VOUCHER 0ATIENT PHARMACIST AND PRESCRIBER AGREE NOT TO SEEK REIMBURSEMENT FOR ALL OR ANY PART OF THE BENElT RECEIVED BY THE PATIENT THROUGH THIS OFFER 4HE FREE TRIAL SUPPLY OF *!.56)! CANNOT BE USED TOWARD ANY OUT OF POCKET COSTS UNDER ANY PLAN SUCH AS TRUE OUT OF POCKET EXPENSE ;4R//0= s 4HIS VOUCHER CAN BE USED ONLY BY ELIGIBLE 53 RESIDENTS AT ANY PARTICIPATING ELIGIBLE RETAIL PHARMACY IN THE 5NITED 3TATES 0RODUCT MUST ORIGINATE IN THE 5NITED 3TATES s 4HIS VOUCHER IS THE PROPERTY OF -ERCK AND MUST BE TURNED IN ON REQUEST s -ERCK RESERVES THE RIGHT TO RESCIND REVOKE OR AMEND THIS OFFER AT ANY TIME WITHOUT NOTICE s It is illegal to sell, purchase, trade, or counterfeit this voucher. Void if reproduced. Void where prohibited by law, taxed, or restricted. s Please read the accompanying Medication Guide and discuss it with your doctor. Also available is the physician Prescribing Information. s Expiration Date: 06/30/2012 Š PARADE Publications 2011. All rights reserved.

Š PARADE Publications 2011. All rights reserved.