DN Forum: Milk allergy - evaporating the myths, condensing the facts - January 2024

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DAIRY NUTRITION FORUM

FORUM PUBLICATION FOR INDUSTRY & HEALTH PROFESSIONALS

Milk allergy - evaporating the myths, Dairy and Sleep condensing the facts from folklore to science Volume 16, Issue 1 | January 2024 Volume 13, Issue 2 | August 2021

Editorial Editorial

Traditionally, the management of food

Summary Points •

Food allergy involves an adverse

Summary immunologicalPoints response against

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a specific food protein, which is normally is this that specific Sleep is a harmless. modifiableItfactor immune response that makesto supports health, contributing food physiological allergy distinct from other both and psychological food hypersensitivities, such functions. Insufficient sleep isas a intolerances. Food allergy is broadly largely unrecognised public health classified as 1) IgE-mediated, 2) nonproblem globally. The circadianorsystem IgE mediated (cell-mediated) 3) responds to many signals including mixed IgE-and cell-mediated. the light-dark cycle, food intake, Accurate diagnosis is key. The drugs gold temperature, physical activity, standard for the diagnosis of a food and stress. allergy is a double blinded placebo controlled oral food challenge, Dietary components can act on but as this is resource heavy, an accurate neurotransmitters which influence clinical history with complimentary sleep, and likewise, sleep deprivation blood tests is the most common can influence metabolic hormones and approach. appetite. This relationship between CMPA rarely occurs in infants that food and the internal circadian clock are exclusively While it is is referred to as breastfed. chrononutrition. still one of the most common food Current indicates dairy allergiesresearch under the age of 3that years has positive effects Cow’s it only affects abouton 1%sleep. of children milk protein is rich tryptophan, under the age of 2in years and up to 90% ofiscases are resolved byserotonin 3-5 which a precursor for both years.

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For young children, unnecessary avoidance of common food allergens may be counterproductive and it is now advisedThese that the maternalplay and melatonin. hormones diet should notinbe restricted during important roles the regulation of pregnancy or breastfeeding, sleep. Small amounts of melatonin as aoccur strategy for preventing the also naturally in cow’s milk. development of food allergy. Fermented milk has been shown to The amount of cow’s milk protein significantly sleep efficiency. excreted in improve breastmilk is so small that Lactic acid bacteria present in any more than 99% of infants with fermented gammaCMPA aredairy likelyproduce to tolerate breastmilk aminobutyric acid, a neurotransmitter from a dairy-consuming mother. which associated with sleep. Calcium Thus,isthere is a shift from moving these mothers to a dairywith free poor diet and inadequacy is associated continued breastfeeding is advised. sleep and therefore, the calcium The management in non-breastfed component of dairy may be another babies involves changing the infant factor which influences sleep. to extensively hydrolysed or amino acid-based formulas, with controlled The overall composition of milk also reintroduction. makes it a nutritious bed-time drink. ItThe provides casein-rich milk ladder plays protein, a pivotalwhich role is encouraged as a pre-sleep intervention in safely reintroducing dairy foods strategy to increase muscle protein to achieve tolerance and resolution. synthesis overnight fordemonstrates both athletes Novel Irish research thatolder the management of IgEand people. mediated CMPA can be safely achieved in GP primary care, using the milk ladder.

allergy adopted a blanket approach Warm milk avoidance before going is a of absolute of to thebed food tradition that has been passed down allergen. However, over the last throughnew generations a practice decade, researchas has deepened to facilitate a restful night’s sleep. our understanding of the complex As with other bedtime routines, immune activity involved, and this has it may be the ritual itself that helps led to novel approaches to optimise to induce the anticipation of sleep. the management of food allergy. Also, drinking milk before falling asleep could be associated with In this edition, explore memories the latest soothing, earlywe childhood scientific research in this area and that evoke calmness. However, it is examine how exposure to potential also believed that naturally occurring components in milk support allergens at the rightcan time, and inthe process sleep. can facilitate an the rightof quantity, adaptive immune response. In this edition of DN Forum, we introduce the science of sleep andpage explore on how On 4 ofthe thisresearch publication, we food interacts with sleep and the feature our updated ‘Common Dairy circadian system. We will focus Myths’ booklet. We hope you enjoy specifically on the scientific this edition and look forward to any evidence which examines the feedback orand comments you wish to role of milk dairy products. share: nutrition@ndc.ie We hope you enjoy this edition of DN Forum and look forward to any feedback or comments you wish to share: nutrition@ndc.ie

Dr Marianne Dr. MarianneWalsh Walsh Nutrition Manager The National Dairy Council (NDC) Council (NDC)


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