Global peripheral blood mononuclear cells market size, share & market forecast 2025

2015 – 2025 GLOBAL PERIPHERAL BLOOD MONONUCLEAR CELLS MARKET FORECAST & OPPORTUNITIES

www.techsciresearch.com MARKET INTELLIGENCE . CONSULTING

Scope of Report Product of Interest (POI): Peripheral Blood Mononuclear Cells

Global peripheral blood mononuclear cells (PBMC) market is expected to grow at a substantial rate in the forecast period. Peripheral blood mononuclear cells (PBMC) also called human mononuclear cells from peripheral blood (HMNC-PB), are extensively used in clinical and research applications.

PBMC are of two types: Lymphocytes and monocytes. Peripheral blood mononuclear cells find their applications in immunology, hematological malignancies, etc.

Market Segmentation

APPLICATION •

Immunology

•

Infectious disease

•

Hematology

•

Others

TECHNIQUE •

Density gradient centrifugation process

•

Leukapheresis

SOURCE

PRODUCT •

Cryopreserved or Frozen PBMC

•

•

•

Humans

•

Animals

REGION

Cultured or Fresh

•

Asia-Pacific

PBMC

•

Europe

Peripheral Blood

•

North America

Mononuclear Cell

•

South America

Isolation &

•

Middle East &

Viability Kits

Year Range Review Period

2015 – 2018 Base Year

2019 Estimated Year

2020 Forecast Period

2021 – 2025

Africa (MEA)

2

Table of Contents S. No.

Contents

1.

Product Overview

2.

Research Methodology

3.

Executive Summary

4.

Voice of Customer

5.

Global Peripheral Blood Mononuclear Cells Market Outlook 5.1.

Market Size & Forecast 5.1.1.

5.2.

5.3.

6.

Page No.

By Value

Market Share & Forecast 5.2.1.

By Product (Cryopreserved or Frozen PBMC, Cultured or Fresh PBMC, Peripheral Blood Mononuclear Cell Isolation & Viability Kits)

5.2.2.

By Application (Immunology, Infectious disease, Hematology and others)

5.2.3.

By Technique (Density gradient centrifugation process, Leukapheresis)

5.2.4.

By Source (Human, Animals)

5.2.5.

By Company (2019)

5.2.6.

By Region

Market Attractiveness Index

Asia-Pacific Peripheral Blood Mononuclear Cells Market Outlook

6.1.

Market Size & Forecast

3

Table of Contents S. No.

Contents 6.1.1.

6.2.

6.3.

Page No.

By Value

Market Share & Forecast 6.2.1.

By Product

6.2.2.

By Application

6.2.3.

By Technique

6.2.4.

By Source

6.2.5.

By Country

Asia-Pacific: Source Analysis 6.3.1.

China Peripheral Blood Mononuclear Cells Market Outlook 6.3.1.1.

Market Size & Forecast 6.3.1.1.1.

6.3.1.2.

6.3.2.

By Value

Market Share & Forecast 6.3.1.2.1.

By Product

6.3.1.2.2.

By Application

6.3.1.2.3.

By Technique

6.3.1.2.4.

By Source

India Peripheral Blood Mononuclear Cells Market Outlook

4

Table of Contents S. No.

Contents 6.3.2.1.

Market Size & Forecast 6.3.2.1.1.

6.3.2.2.

6.3.3.

By Value

Market Share & Forecast 6.3.2.2.1.

By Product

6.3.2.2.2.

By Application

6.3.2.2.3.

By Technique

6.3.2.2.4.

By Source

Japan Peripheral Blood Mononuclear Cells Market Outlook 6.3.3.1.

Market Size & Forecast 6.3.3.1.1.

6.3.3.2.

6.3.4.

Page No.

By Value

Market Share & Forecast 6.3.3.2.1.

By Product

6.3.3.2.2.

By Application

6.3.3.2.3.

By Technique

6.3.3.2.4.

By Source

Singapore Peripheral Blood Mononuclear Cells Market Outlook 6.3.4.1.

Market Size & Forecast

5

Table of Contents S. No.

Contents 6.3.4.1.1.

6.3.4.2.

6.3.5.

By Value

Market Share & Forecast 6.3.4.2.1.

By Product

6.3.4.2.2.

By Application

6.3.4.2.3.

By Technique

6.3.4.2.4.

By Source

Australia Peripheral Blood Mononuclear Cells Market Outlook

6.3.5.1.

Market Size & Forecast

6.3.5.1.1.

6.3.5.2.

7.

Page No.

By Value

Market Share & Forecast 6.3.5.2.1.

By Product

6.3.5.2.2.

By Application

6.3.5.2.3.

By Technique

6.3.5.2.4.

By Source

Europe Peripheral Blood Mononuclear Cells Market Outlook 7.1.

Market Size & Forecast 7.1.1

By Value

6

Table of Contents S. No.

Contents 7.2.

7.3.

Page No.

Market Share & Forecast

7.2.1.

By Product

7.2.2.

By Application

7.2.3.

By Technique

7.2.4.

By Source

7.2.5.

By Country

Europe: Source Analysis

7.3.1.

France Peripheral Blood Mononuclear Cells Market Outlook

7.3.1.1.

Market Size & Forecast

7.3.1.1.1.

7.3.1.2.

7.3.2.

By Value

Market Share & Forecast 7.3.1.2.1.

By Product

7.3.1.2.2.

By Application

7.3.1.2.3.

By Technique

7.3.1.2.4.

By Source

Germany Peripheral Blood Mononuclear Cells Market Outlook

7

Table of Contents S. No.

Contents 7.3.2.1.

Market Size & Forecast 7.3.2.1.1.

7.3.2.2.

7.3.3.

By Value

Market Share & Forecast 7.3.2.2.1.

By Product

7.3.2.2.2.

By Application

7.3.2.2.3.

By Technique

7.3.2.2.4.

By Source

United Kingdom Peripheral Blood Mononuclear Cells Market Outlook 7.3.3.1.

Market Size & Forecast

7.3.3.1.1.

7.3.3.2.

7.3.4.

Page No.

By Value

Market Share & Forecast

7.3.3.2.1.

By Product

7.3.3.2.2.

By Application

7.3.3.2.3.

By Technique

7.3.3.2.4.

By Source

Italy Peripheral Blood Mononuclear Cells Market Outlook

8

Table of Contents S. No.

Contents 7.3.4.1.

Market Size & Forecast

7.3.4.1.1.

7.3.4.2.

8.

Page No.

By Value

Market Share & Forecast 7.3.4.2.1.

By Product

7.3.4.2.2.

By Application

7.3.4.2.3.

By Technique

7.3.4.2.4.

By Source

North America Peripheral Blood Mononuclear Cells Market Outlook 8.1.

Market Size & Forecast 8.1.1.

8.2.

8.3.

By Value

Market Share & Forecast 8.2.1.

By Product

8.2.2.

By Application

8.2.3.

By Technique

8.2.4.

By Source

8.2.5.

By Country

North America: Source Analysis 8.3.1.

United States Peripheral Blood Mononuclear Cells Market Outlook 8.3.1.1.

Market Size & Forecast

9

Table of Contents S. No.

Contents 8.3.1.1.1.

8.3.1.2.

8.3.2.

By Value

Market Share & Forecast 8.3.1.2.1.

By Product

8.3.1.2.2.

By Application

8.3.1.2.3.

By Technique

8.3.1.2.4.

By Source

Mexico Peripheral Blood Mononuclear Cells Market Outlook 8.3.2.1.

Market Size & Forecast

8.3.2.1.1.

8.3.2.2.

8.3.3.

Page No.

By Value

Market Share & Forecast 8.3.2.2.1.

By Product

8.3.2.2.2.

By Application

8.3.2.2.3.

By Technique

8.3.2.2.4.

By Source

Canada Peripheral Blood Mononuclear Cells Market Outlook 8.3.3.1.

Market Size & Forecast

8.3.3.1.1.

8.3.3.2.

By Value

Market Share & Forecast

10

Table of Contents S. No.

9.

Contents 8.3.3.2.1.

By Product

8.3.3.2.2.

By Application

8.3.3.2.3.

By Technique

8.3.3.2.4.

By Source

Page No.

South America Peripheral Blood Mononuclear Cells Market Outlook 9.1.

Market Size & Forecast 9.1.1.

9.2.

9.3.

By Value

Market Share & Forecast 9.2.1.

By Product

9.2.2.

By Application

9.2.3.

By Technique

9.2.4.

By Source

9.2.5.

By Country

South America: Source Analysis 9.3.1.

Brazil Peripheral Blood Mononuclear Cells Market Outlook 9.3.1.1.

Market Size & Forecast 9.3.1.1.1

9.3.1.2.

By Value

Market Share & Forecast 9.3.1.2.1.

By Product

11

Table of Contents S. No.

Contents

9.3.2.

9.3.1.2.2.

By Application

9.3.1.2.3.

By Technique

9.3.1.2.4.

By Source

Argentina Peripheral Blood Mononuclear Cells Market Outlook 9.3.2.1.

Market Size & Forecast 9.3.2.1.1

9.3.2.2.

9.3.3.

Page No.

By Value

Market Share & Forecast 9.3.2.2.1.

By Product

9.3.2.2.2.

By Application

9.3.2.2.3.

By Technique

9.3.2.2.4.

By Source

Colombia Peripheral Blood Mononuclear Cells Market Outlook 9.3.3.1.

Market Size & Forecast 9.3.3.1.1

9.3.3.2.

By Value

Market Share & Forecast 9.3.3.2.1.

By Product

9.3.2.2.2.

By Application

9.3.2.2.3.

By Technique

9.3.2.2.4.

By Source

12

Table of Contents S. No. 10.

Contents

Page No.

Middle East & Africa Peripheral Blood Mononuclear Cells Market Outlook 10.1.

Market Size & Forecast

10.1.1.

10.2.

10.3.

By Value

Market Share & Forecast 10.2.1.

By Product

10.2.2.

By Application

10.2.3.

By Technique

10.2.4.

By Source

10.2.5.

By Country

MEA: Source Analysis 10.3.1.

South Africa Peripheral Blood Mononuclear Cells Market Outlook 10.3.1.1.

Market Size & Forecast

10.3.1.1.1.

10.3.1.2.

10.3.2.

By Value

Market Share & Forecast 10.3.1.2.1.

By Product

10.3.1.2.2.

By Application

10.3.1.2.3.

By Technique

10.3.1.2.4.

By Source

Saudi Arabia Peripheral Blood Mononuclear Cells Market Outlook 10.3.2.1.

Market Size & Forecast

13

Table of Contents S. No.

Contents 10.3.2.1.1.

10.3.2.2.

10.3.3.

By Value

Market Share & Forecast 10.3.2.2.1.

By Product

10.3.2.2.2.

By Application

10.3.2.2.3.

By Technique

10.3.3.2.4.

By Source

UAE Peripheral Blood Mononuclear Cells Market Outlook 10.3.3.1.

Market Size & Forecast 10.3.3.1.1.

10.3.3.2.

11.

Page No.

By Value

Market Share & Forecast

10.3.3.2.1.

By Product

10.3.3.2.2.

By Application

10.3.3.2.3.

By Technique

10.3.3.2.4.

By Source

Market Dynamics 11.1.

Drivers

11.2.

Challenges

12.

Market Trends and Developments

13.

Clinical Trials

14

Table of Contents S. No. 14.

Contents

Page No.

Competitive Landscape 14.1.

Competition Outlook

14.2.

Company Profiles (Top 10 Global Player)

15.

Strategic Recommendations

16.

About Us & Disclaimer

15

RESEARCH METHODOLOGY

Research Methodology

Market Profiling

In-depth secondary research was conducted to determine top players in the global peripheral blood mononuclear cells market, overall market size and segmental market size.

Formulating Questionnaire

In order to conduct industry experts’ interviews, TechSci formulated a detailed discussion guide.

Developing List of Respondents

Data Collection

Data Validation

Data obtained as a result of primary and secondary research was validated through rigorous triangulation.

TechSci conducted interviews with industry experts and industry players for data collection and verification.

List of industry players and industry specialists was developed.

Primary Research

Data Collection

Data Filter & Analysis

Research & Intelligence

Actionable Insights

Desk Research

✓ Identifying Key Opinion Leaders

Business Solution

✓ Questionnaire Design

✓ ✓

LinkedIn TechSci Internal Database

✓ ✓ ✓ ✓ ✓

Company Websites Company Annual Reports White Paper Study Financial Reports Investor Presentations Regulatory Body Associations, etc.

Company Analysis

✓ Recent Developments

✓ Market Participants

✓ Market Changing Aspects/Dynamics

✓ Key Strengths

✓ Conclusion

Secondary Research ✓ ✓

The data was scrutinized using MS-Excel, statistical tools and internal proprietary database to obtain qualitative and quantitative insights about the global peripheral blood mononuclear cells market.

✓ Government Policies

✓ In-depth Interviews

Primary Research

Data Analysis

Paid Sources

✓ ✓

Factiva Hoovers

17

Research Methodology Baseline Methodology

Our dedicated team of industry experts has monitored and analyzed various aspects of the global peripheral blood mononuclear cells market. The team has analyzed the outlook of various segments of this market, while considering the major influencing factors such as increasing benefits of peripheral blood mononuclear cells. The study includes market forecasting, which would enable our clients to take better decisions while planning their strategy to achieve sustainability in the global peripheral blood mononuclear cells market.

Methodology Followed for Calculation of Market Size:

• Market Size by Value: Market size, in terms of value, for the year 2019 was calculated based on information collected through exhaustive secondary research and primary surveys, with various key opinion leaders/stakeholders, such as peripheral blood mononuclear cells companies, channel partners, market influencers & end users, industry experts, and other industry participants.

• The team interviewed more than 15 – 20 peripheral blood mononuclear cells companies, 100 – 120 end users, and 15 – 20 industry experts and other value chain stakeholders in the global peripheral blood mononuclear cells market to obtain the overall market size from 2015 to 2019, which was validated by the Delphi technique. Taking standard deviation into consideration, the market size was averaged out, to arrive at the market size data during 2015-2019.

18

Research Methodology • Respondents were asked about the current and future market growth rates, market shares by product, by application, by technique, by source, by company and by region. Removing the outlier responses, the geometric mean of growth estimates and provider wise revenue shares generated

across various segments were considered, to arrive at the final revenue shares. Revenue shares generated across various segments were further triangulated from other stakeholders.

Methodology Followed for Calculation of Market Shares: Market by product, by application, by technique, by source, by company and by region were calculated based on the responses received through

primary surveys with industry experts, in which the respondents were asked about the market shares or revenue generated from various segments of peripheral blood mononuclear cells markets. The final shares were calculated by taking the geometric mean of the responses gathered from key opinion leaders after eliminating the outliers.

Methodology Followed for Forecasting: • TechSci Research performed periodical checks on data collected through the surveys with logic checks and analyzed the survey results in SPSS/Tableau Software.

• Data triangulation techniques were applied to fill the gaps and to present a more meaningful picture of the market. To forecast global peripheral blood mononuclear cells market, TechSci Research used various forecast techniques such as: ✓

Moving Average

✓

Time Series Analysis

✓

Regression Analysis

✓

Econometric and Judgmental Analysis

19

Research Methodology TechSci Research used its own forecast tool, which is based on the growth of various allied industries in respective regions. TechSci Research also used the impact analysis during short, medium and long term period to estimate the demand and to reach accurate market numbers. It should be noted that the figures compiled are only for the organized market including market share data. The currency used in the report is the United States Dollar (USD),

with the market size indicated in USD million.

Partial List of Companies Interviewed ▪

Astarte Biologics, Inc.

▪

ATZLabs

▪

BioIVT

▪

BioLegend, Inc.

▪

BioVision

▪

Bio-Rad

▪

Cell Applications, Inc

▪

Celgene

▪

Creative Bioarray

▪

Dapcel, Inc

▪

HemaCare

▪

iXCells Biotechnologies

▪

Miltenyi Biotec

▪

Merck

▪

Novo Nordisk

▪

Precision Medicine

▪

Qiagen NV

▪

STEMCELL Technologies Inc.

▪

Thermo Fisher Scientific

▪

ZenBio, Inc

Key Secondary Sources ▪ World Bank ▪ TechSci Research Proprietary Database & Knowledge Repository ▪ Company Annual Reports ▪ Industry Magazines ▪ Industry Reports ▪ News Dailies ▪ Credible Paid Databases

20

INDUSTRY BRIEF According to TechSci Research report, “Global Peripheral Blood Mononuclear Cells Market By Product (Cryopreserved or Frozen PBMC, Cultured or Fresh PBMC, Peripheral Blood Mononuclear Cell Isolation & Viability Kits), By Application (Immunology, Infectious Disease, Hematology and Others), By Technique (Density Gradient Centrifugation Process, Leukapheresis), By Source (Human, Animals), By Region, Forecast & Opportunities, 2025”, the global market of peripheral blood mononuclear cells is projected to grow at a steady rate during the forecast period. PBMC are also called Human Mononuclear Cells from Peripheral Blood (HMNCPB) and are made up of lymphocytes & monocytes, and in humans, major composition of PBMC consist of lymphocytes, followed by monocytes and dendritic cells. PBMC is crucial to carry out the studies related to biology and pathology and are also quite useful in clinical applications and research. Scientists are researchers are trying to expound the various characteristics that a cell can possess. Additionally, PMBCs help to find these characteristics which are important for research areas such as immunology, transplant immunology, vaccine development, hematological malignancies, among others. However, developing nations tend to lack research practices due to less research institutes which can eventually lead to less usage of PBMCs, thusly restraining the market growth.

The global peripheral blood mononuclear cells market is segmented into product, application, technique, source, company and region. Based on product, the market is segmented into cryopreserved or frozen PBMC, cultured or fresh PBMC and peripheral blood mononuclear cell isolation & viability kits. Cryopreserved PBMC segment is expected to dominate the market during the forecast period as frozen PBMC find their applications in clinical trials. Moreover, PBMCs can be used for long durations of time if they are stored in a proper way and at lower temperatures. They can even substitute fresh PBMCs in few applications and thus, making it feasible for the scientists and researchers to carry out various tests in one laboratory avoiding inter-laboratory problems.

Based on regional analysis, as of 2019, North America holds the largest market share of peripheral blood mononuclear cells and is anticipated to hold its position during the forecast tenure. This is due to the presence of pre-existing PBMC based research organizations and lab service providers in the region.

Some of the major players in global peripheral blood mononuclear cells market include Astarte Biologics, Inc., ATZLabs, BioIVT, BioLegend, Inc., BioVision, Bio-Rad, Cell Applications, Inc., Celgene, Creative Bioarray, Dapcel, Inc, HemaCare, iXCells Biotechnologies, etc. In order to expand their market share, the companies adopt various strategies mainly collaborations to attract more customers. For instance, Miltenyi Biotec, a European PBMC based company launched a new MACSprep PBMC Isolation Kit in June 14, 2017. The kit is used for processing and diagnosis of small blood samples as it prepares extremely pure PBMCs via the blood in a very short span of time without using the procedure of centrifugation.

“Global peripheral blood mononuclear cells market is anticipated to witness a steady growth over the course of next five years. The increase in number of diseases and rise in number of PBMC based research organizations are some of the major factors driving the market across the globe. Additionally, increasing incidents of autoimmune and metabolic diseases are positively influencing the growth of the market as PBMC is used in such studies related to such diseases.,” said Mr. Karan Chechi, Research Director with TechSci Research, a research based global management consulting firm.

21

SAMPLE DATA - SNAPSHOT Global Peripheral Blood Mononuclear Cells Market Size, By Value (USD Million), 2015-2025F

5.00

2015

8.00

7.00

6.00

CAGR By Value

XX%

9.00

10.00

2019

2020E

11.00

12.00

13.00

14.00

CAGR By Value

2025F

YY%

By Value (USD Million)

15.00

North America Peripheral Blood Mononuclear Cells Market Share, By Product, By Value, 2015–2025F Cryopreserved or Frozen PBMC 2025F

2024F 2023F 2022F 2021F 2020E 2019 2018 2017 2016 2015

Cultured or Fresh PBMC

33% 33% 33% 33% 33% 33% 33% 33% 33% 33% 33%

Peripheral Blood Mononuclear Cell Isolation & Viability Kits

33% 33% 33% 33% 33% 33% 33% 33% 33% 33% 33%

34% 34% 34% 34% 34% 34% 34% 34% 34% 34% 34%

United States Peripheral Blood Mononuclear Cells Market Share, By Source, By Value, 2015–2025F Humans 2025F 2024F 2023F 2022F 2021F 2020E 2019 2018 2017 2016 2015

50% 50% 50% 50% 50% 50% 50% 50% 50% 50% 50%

Animals

50% 50% 50% 50% 50% 50% 50% 50% 50% 50% 50%

22

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About Us & Disclaimer

TechSci Research is a global market research and consulting company with offices in the US, UK and India. TechSci Research provides market research reports in number of areas to organizations. The company uses innovative business models that focus on improving productivity, while ensuring creation of high-quality reports. The proprietary forecasting models use various analyses of both industry-specific and macroeconomic variables on a state-by-state basis to produce a unique ‘bottom-up’ model of a country, regional and

global industry prospects. Combined with the detailed analysis of company activity and industry trends, the result is a uniquely rich evaluation of the opportunities available in the market.

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Disclaimer The contents of this report are based on information generally available to the public from sources believed to be reliable. No representation is made that it is timely, accurate or complete. TechSci Research has taken due care and caution in compilation of data as this has been obtained from various sources including which it considers reliable and firsthand.

However, TechSci Research does not guarantee the accuracy, adequacy or completeness of any information and it is not responsible for any errors or omissions or for the results obtained from the use of such information and especially states that it has no financial liability whatsoever to the subscribers / users of this report. The information herein, together with all estimates and forecasts, can change without notice. All the figures provided in this document are indicative of relative market size and are strictly for client’s internal consumption. Usage of the same for purpose other than internal will require prior approval of TechSci Research.