Stem Cell Transplantation in India

STEM CELL TRANSPLANTATION IN INDIA

BY STEM CELL CURE PVT. LTD. Best Stem Cell Development company

A method of replacement immature blood-forming cells in the bone marrow that are destroyed by medication, radiation, or disease. Stem cells square measure injected into the patient and build healthy blood cells. A stem cell transplant is also autologous (using a patient’s own stem cells that were saved before treatment), allogeneic (using stem cells given by somebody who isn't a regular twin), or syngeneic (using stem cells given by a regular twin).

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THE STEM CELL TRANSPLANT PROCESS All kids undergoing a stem transplant area unit given high-dose chemotherapy to create space in their bone marrow for the new stem cells suppress their system to forestall graft rejection and destroy cancer cells in their body. when this conditioning regime, they're given some days’ rest before their transplant.

Like a transfusion, stem cells square measure given to a child through a blood vessel tube. kids square measure awake through this painless method. It typically takes 2 to 6 weeks for the engraftment to “take” and for the stem cells to multiply and build new blood cells.

Minor aspect effects, like fever, chills, and shortness of breath, will accompany the infusion of latest stem cells. a lot of important complications, together with graft rejection and graft-versus-host illness (a condition within which the donor’s immune cells attack the patient’s body), will occur following the transplant. Learn a lot of regarding what to expect throughout a somatic cell transplant.

TRANSPLANTATION AND RECOVERY: Physicians sometimes transplant the harvested stem cells into the patient’s blood within the same method that they might administer a blood transfusion.

Over the subsequent days and weeks, the transplanted stem cells migrate to the marrow house within the bones, wherever they bit by bit begin to provide new blood cells.

Between 2 and 3 weeks once the transplant, physicians sometimes begin to notice freshly shaped blood cells within the patient’s blood. As time passes, a productive transplant graft can manufacture red blood cells, white blood cells, and platelets.

During the days directly when transplantation, patients want a good deal of medical support. you will receive transfusions of irradiated blood merchandise, like platelets and red blood cells, similarly as antibiotics to stop and treat microorganism, viral, and fungus infections, that area unit possible to occur within the initial 3 months when transplantation. Patients also are prone to complications of the therapy with or while not therapy, which can need extra treatments.

Most patients stay at the hospital for many weeks when the transplant. throughout this point, preventive measures square measure taken to safeguard against infection. All those who enter the room are needed to wear protecting gloves and masks and to scrub their hands with antiseptic soap. Sometimes people coming into the area have to be compelled to cowl their clothing with clean, disposable gowns. Fresh fruit, flowers, plants, or cut flowers square measure prohibited from the patient’s room, as these will carry disease-causing molds and bacteria.

MANAGEMENT OF COMPLICATIONS

Our researchers are devoting important efforts to raising the supportive care of patients undergoing autologous stem cell transplantation. Patients who have received high doses of therapy or irradiation could develop acute or chronic complications — as well as infections, bleeding, and anemia — till blood cell production returns to normal. Liver and respiratory organ issues may develop when a transplant.

One potential complication is mucositis, a condition during which the cells that line the mouth and internal organ tract area unit destroyed by the high-dose chemotherapy with or while radiation therapy. Symptoms include mouth pain and ulcers, abdominal pain, diarrhea, and infection.

Our researchers have additionally pioneered the utilization of the body serum markers IL-6 and IL-12, which might be measured in patients who develop fever when stem cell transplantation to see whether or not the fever is caused by the transplant method or is due to an infection.

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