Salvona Hair Care Technology

Innovative Technology for Consumer Products

Salvona offers a wide array of encapsulated actives for hair care.

These technologies are for anti-aging and cosmetics applications.

Hair Care Technology A GUIDE TO PRO DUCT DEVELO PM ENT

TECHNOLOGIES TO KEEP THE HAIR NATURAL, HEALTHY, BEAUTIFUL, AND GROWING Learn more about how these technologies can help you. Contact us for custom encapsulation at www.salvona.com

Proudly invented & manufactured in the United States of America.

Salvona and HydroSal are registered trademarks of Salvona LLC.

Tel 1-(844) SALVONA | sales@salvona.com | www.salvona.com 2521 Kuser Road, Hamilton NJ 08691, USA v101717

hydrophilic surface.

SalSphere™ Natural Hair Growth Promoter TECHNOLOGY REVIEW

833 S

Contains Natural Identical Technology

Timed and Targeted Release of Natural Apple Extract for Hair Growth TECHNOL OG Y W HAT I T DO ES C O N TA I N S Contains Natural Technology

SalSphere® Healthy Scalp, 8397

• Keeps the scalp healthy without flaky skin/dandruff • Relieves itchy scalp • Suitable for sensitive skin • Suggested for scale eczema and

SCALP

dandruff

0.1 - 0.3 microns (Figure 1). The core of the sphereC andinfused tea tree extract suitable with Procyanidin B2 and the shell is made o to treat dandruff on the scalp hydrophilic surface.1: Structure of SalSphere™ Natura Figure • Blend of antiseptic • Encapsulation of beta

hydroxy acid (salicylic acid)

Promoter with its shell and a core containing p

botanicals with anti-fungal properties

A • An encapsulated natural botanical • Alcohol-free complex of HydroSalTM to provide long-lasting protection natural plant is extracts with Natural Natural blend SalSphere™ Hair Growth Promoter (NHGP) from bacteria and fungi proven antiseptic and antiAntiseptic, a targeted system that promotes hair growth fungal properties: tea tree oil, 8419 delivery • The technology extends the retention by 10 times and thickness through natural ingredients.

• Broad spectrum effectiveness

v.0722 P

olive leaf extract, clove oil,

Shell

Procyanidin B

Core

peppermint oil, eucalyptus, thymol, grape fruit seed

Figure 1: Structure of SalSphere™ Natural Hair Grow

Procyanidin oligomers from apples have been clinically Promoter with its shell and a core containing procyanidin B shown to re-grow hair. In one study, hair thickness A B hair growth and • Natural apple extract increased by 80%.• Promotes In thenatural same study, hair growth SalSphere thickness containing Procyanidin B2, Natural Hair activity increased by• Targeted 300% compared to control and which is clinically proven to Growth delivery, deposits actives promote growth Promoter, hair follicles 160% compared to directly FDAintoapproved minoxidil, withhairno SalSphere™ Natural Hair Growth Promoter (NHGP) is 8337 • Botanical polyphenols • Alcohol-free, natural remedy for men 1 Procyanidin side effects (Figure 3).

B2 also reduces & women a targeted delivery system that promotes hair growth • Turns a water soluble extract into inßammation via anti-oxidative and protease inhibition and thickness through natural ingredients. a lipid base sphere that is able to 2 abilities , providing healthy scalp for hair deposita and slowly release • Stabilizes polyphenols; encapsulation rejuvenation.

Procyanidin oligomers from apples haveoxidation been that reduces andclinically color A B change shown to re-grow hair. In one study, hair thickness However, there are issues associated with using thisB Figure 2: Illustration of before (A) and after increased by 80%.

In the same study, hairnewgrowth • Technology to stimulate hair • Natural blend of caffeine to SalSphere with a product containing procyanidin B2. Th ingredient.

Procyanidin which growth B2 is water-soluble, hair follicles and Hair activity increased by 300% compared to control and awaken taken from a study conducted by scientists a retain hair • Time-release,into long-lasting limits itsStimulator, ability to penetrate the stimulation hair follicles, and it 8428 160% compared to FDA approved minoxidil, no • Caffeine inhibits 5-alphaof Tokyo.3 to revitalize and retain morewith hair is highly unstable, creating a challenge for formulators the enzyme • Exhibit results side effects (Figure 3).1 Procyanidin B2in weeks also reduces reductase, associated with hair loss ingredients, safe for sensitive Mechanism of Action and compromising • Natural efÞcacy.

SalSphereª NHGP is inßammation via anti-oxidative and protease inhibition skin designed to preserve the potency of apple extract • Time release of caffeine extends abilities 2 , providing a healthy scalp for the hair Procyanidin B2 enhances the proliferativ benefits ingredients while targeting its delivery to hair follicles A B rejuvenation. hair epithelial cells compared to minoxidil on the scalp. The purpose of SalSphere™ is to These cells, including stem cells and oute increase the efÞcacy of the functional ingredient.

However, there are issues associated with using This this brochure Figure represents a few examples 2: only Illustration of before (A) and after (B) treatme cells, activate the reversion of the teloge of Salvona technologies for hair care. with a product containing procyanidin B2.

This picture w ingredient. Procyanidin B2 is water-soluble, which anagen (growth) phase by promoting from athe study conducted How the Technology Helps Youtaken us for custom encapsulation atby scientists at the Univers limits its ability to penetrate into the hair follicles,Please and itcontact 3 of Tokyo. hair follicles from near the epidermis in sales@salvona.com or callof1-(844) SAL-VONA is highly unstable, creating a challenge for formulators SalSphere™ is a proprietary technology comprised of dermal layers. This phenomenon results i Mechanism of Action and compromising efÞcacy. SalSphereª NHGP is sub-micron spheres with a diameter of approximately of both hair diameter and density. 4 designed toProudly preserve the potency of apple extract invented & manufactured in the United States of America.

Salvona and HydroSal are registered trademarks of Salvona LLC. Procyanidin B2 enhances the proliferative capacity ingredients while targeting its delivery to hair follicles Contact team with your questions information.

2521 Kuser Road, Hamilt hairmore epithelial cells compared to minoxidil and contro on the scalp.

Theour purpose of SalSphere™ is or to to get extract

HEALTHY HAIR

®

®

Hair Care Technology

TECHNOLO G Y

C O N TA I N S

• Longer-lasting fragrance release, stabilized fragrance prevents discoloration, triggered release with natural perspiration

• Fragrance

DRY TREATMENTS

MultiSal® Fragrance, 2402

W HAT I T DO ES

• Thermal stability, suitable for incorporating into hot processes • Transforms liquid into fine powder that blends into the skin

MultiSal® Sebum Control, 8123

• Polymeric super absorber of sebum • Reduces excess sebum secretion • Extends styling durability over time, reduces shine

• Super sebum absorbing polymers • Zinc PCA

• Volumizing hair

SalSphere® Color Guard, 8384

• Reduces the frequency of hair dying and • Multi-faceted protection associated cost and reduce the exposure using botanicals and SPF to chemicals ingredients • Long-lasting hair color retention preventing chemical stripping and sun (UV) fading

• Broccoli seed extract • Cranberry extract • Octyl methoxy cinnamate

• Compatible with shampoo, conditioner, and spray • Replenish shine and healthy-looking hair • Long-lasting frizz control, especially in humid environments

• Time release, waterresistant silicone phenyl trimethicone (PTM)

• Doesn’t weigh hair down, provides more management, smoother hair • Maintains sleek, straight, and healthylooking hair

SalSphere® Hair Rejuvenator, 8391

HydroSalTM Heat Protection, 8381

A

• Anti-aging for hair: restores and maintains healthy hair, provides extra shine, moisture, and softness

• Potent and special botanical extracts

• Time release botanical essential oils rich in linoleic acid and proanthocyanidin provides regeneration properties to the hair & scalp

• Coconut extract

• For daily use, especially after coloring or styling

• Olive oil

• Protects hair from severe heat damage while delivering fragrance

• Film-forming polymers

• Fragrance burst alerts user of excess heat

• Argan oil

• Heat activated conditioning agents are released upon use of electrical styling equipment

• Anti-aging for hair: thicker & smoother with vibrant natural shine, silkiness, and greater manageability

B

• Broccoli seed extract • Grape seed extract • Safflower extract, known to reduce hair loss

• Thermal protection agents • Castor oil • Vitamin B-5 • Sunflower seed oil

• Pro keratin; vital to hair • Time release, longer-lasting benefits

• Envelope hair with layer of keratin to enhance thickness, natural shine & styling • Suitable for daily use, wash off & leave on

Tel 1-(844) SALVONA | sales@salvona.com | www.salvona.com 2521 Kuser Road, Hamilton NJ 08691, USA v101717

SENSORY

HydroSalTM SalSilk, 8392

B

COSMETICS

SalSphere® Style Protector, 8388

A

Hair Care Technology

FORMULATION EXAMPLES

Indicates Salvona Technology

HAIR SPRAY

SERUM

containing HS SalSilk

containing SS Hair Rejuvenator

Ingredients

(W/W %)

Ingredients

(W/W %)

Water 93.55

Water 77.60

HydroSalTM SalSilk

5.00

Propanediol 5.00

Phenoxyethanol 0.75 Ethylhexylglycerin

SalSphere® Hair Rejuvenator 4.00

Glycerin 0.50

Hydroxypropyl Phosphate 2.00 Lauryl Glucoside Crosspolymer

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Polyhydroxy Stearic Acid

0.20

1.00

Phenoxyethanol 1.00 Ethylhexylglycerin Acrylates/C10-30 Alkyl Acrylate Crosspolymer

0.25

Disodium EDTA

0.10

HydroSalTM FreshCool

0.05

GEL

DRY SHAMPOO

containing HS Heat Protection

containing MS Sebum Control

Ingredients

(W/W %)

Ingredients

(W/W %)

Water 93.20

Talc 75.95

HydroSalTM Heat Protection

Tapioca Starch, Polymethylsilsesquioxane

5.00

Phenoxyethanol 1.00 Ethylhexylglycerin

20.00

MultiSal® Fresh Ocean Scent 2.00

Carbomer 0.50

MultiSal® Sebum Control

Arginine 0.10

Silica 0.05

Disodium EDTA

0.10

Polyhydroxy Stearic Acid

0.10

2.00

ENDLESS POSSIBILITIES WITH SALVONA’S TECHNOLOGIES Please contact us for custom encapsulation at sales@salvona.com or call 1-(844) SAL-VONA

Proudly invented & manufactured in the United States of America.

Salvona and HydroSal are registered trademarks of Salvona LLC.

Tel 1-(844) SALVONA | sales@salvona.com | www.salvona.com 2521 Kuser Road, Hamilton NJ 08691, USA v101717