http://www.rosco.dk/pdf/IFU-Neo-S-nl-091105-071107-091105

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Rosco Diagnostica Zone diameter in mm NEO-SENSITABS * Potency Cefpodoxime 30 µg (ESBL screening) n g Haemophilus spp. S. pneumoniae (non-meningeal) b N. gonorrhoeae Cefquinome (Vet)** 30 µg h Ceftazidime 30 µg (ESBL screening) g Haemophilus spp. N. gonorrhoeae S. maltophilia, B. cepacia Acinetobacter spp. Ceftazidime+Clavulanate 30+10 µg Ceftiofur (Vet) 30 µg Ceftizoxime h 30 µg S. pneumoniae (3rd gen. cephalosporins) j Ceftriaxone h 30 µg (ESBL screening) g Haemophilus spp. S. pneumoniae (use ceftizoxime) j S. pneumoniae (non-meningeal) b Beta-haemolytic Streptococcus spp. Streptococcus spp. (viridans) d N. gonorrhoeae Cefuroxime (parenteral) h o 60 µg Haemophilus spp. j N. gonorrhoeae Cefuroxime (peroral) h o 60 µg S. pneumoniae (non-meningeal) b Cephalexin** h 30 µg Cephalothin h i 66 µg Haemophilus spp. Cephradine** h 60 µg DBV0005I

Code CFPOX

CFQUI CEZDI

CZ+CL CFTIO CEZOX

S ≥ 25 ≥ 28 ≥ 32 ≥ 32 ≥23 ≥ 20 ≥ 28 ≥ 32 ≥ 22 ≥ 20

I R 24-21 ≤ 20 < 20 31-27 ≤ 26 22-20 ≤ 19 19-17 ≤ 16 < 24 21-17 ≤ 16 19-17 ≤ 16 (detection of ESBL) 22-20 ≥ 23 ≤ 19 22-20 ≥ 23 ≤ 19 ≥ 30 ≤ 25

ATCC 25922 29-35

Quality Control S. P. E. H. S. aureus aeruginosa faecalis influenzae pneumoniae ATCC ATCC ATCC ATCC ATCC 25923 27853 29212 49247 49619 -

29-35 27-33

26-34 18-23

24-31 22-30

-

29-36

-

≥8 ≥ 32 -

23-29 -

24-32 -

-

-

-

28-34

29-35

21-28

17-24

-

32-39

33-40

24-30

29-36

-

-

20-26

32-38

24-30

29-36

-

-

20-26

32-38

16-21 21-27

32-40

-

18-23

20-25

-

20-26

-

-

-

-

-

Break- points MIC µg/ml S ≤2 ≤2 ≤ 0.5 ≤ 0.5 ≤2 ≤8 ≤2 ≤ 0.5 ≤8 ≤8

R ≥8 >8 ≥2 ≥8 ≥ 32 >2 ≥ 32 ≥ 32

≤2 ≤8 ≤ 0.5

E. coli

(CTAX etc.)

CETRX

CEFUR

CEFUR CFLEX CLOTN CFRAD

≥ 20 ≥ 28

19-17 -

≤ 16 < 24 -

≤8 ≤2

≥ 32*** >2 -

≥ 28 ≥ 26 ≥ 28 ≥ 32 ≥ 23 ≥ 28 ≥ 32 ≥ 25 ≥ 30 ≥ 20 ≥ 23 ≥ 28 ≥ 23

27-24 27-24 22-20 27-24 31-27 24-21 29-27 19-17 22-20 22-20

≤ 23 ≤ 23 ≤ 19 ≤ 23 ≤ 26 ≤ 20 ≤ 26 ≤ 16 ≤ 19 ≤ 23 ≤ 19

≤1 ≤ 0.5 ≤1 ≤ 0.25 ≤8 ≤4 ≤1 ≤4 ≤1 ≤8 ≤8 ≤8 ≤8

≥4 ≥4 ≥ 32 ≥ 16 ≥4 ≥ 32 ≥4 ≥ 32 ≥ 32 (amp R) ≥ 32

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