Tuesday Abstracts respectively. Patients should be counselled about these risks before embarking on pregnancy and when pregnant should book high-risk obstetric and urology cover. Delivery should be by elective Caesarean Section with a urologist present in theatre. 1110 – 1120 Maternal Health and Pregnancy Outcomes Among Women of Refugee Background in Australia Gibson-Helm M1*, Teede H1,2, Cheng I-H3,4, Block A5, Knight M6, East C6,7,8, Wallace E6,7,9, Boyle J1 1 Monash Applied Research Stream, School of Public Health and Preventive Medicine, Monash University, Clayton, Victoria 2 Diabetes and Vascular Medicine Unit, Monash Health, Clayton, Victoria 3 Southern Academic Primary Care Research Unit, (Monash University, South Eastern Melbourne Medicare Local, South Eastern Health Providers Association, Monash Health), Dandenong, Victoria 4 South Eastern Melbourne Medicare Local, Dandenong, Victoria 5 Refugee Health Service, Monash Health, Clayton, Victoria 6 Monash Women’s Services, Monash Health, Clayton, Victoria 7 The Ritchie Centre, Monash Institute of Medical Research, Clayton, Victoria 8 School of Nursing and Midwifery, Monash University, Clayton, Victoria 9 Department of Obstetrics and Gynaecology, Monash University, Clayton, Victoria Background: Migration is associated with increased risks of adverse pregnancy outcomes. However, it is unclear whether the risks differ between migrants of refugee and non-refugee background. Objective: To describe maternal health, pregnancy care attendance, and pregnancy outcomes among women of refugee background compared to nonrefugee migrant women. Method: Retrospective, observational study of migrant women born in nonhumanitarian and humanitarian source countries (HSC) having a singleton birth at a large metropolitan maternity service in Australia 2002-2011 (n=14870 and n=3603 respectively). Results: Compared to non-HSC migrant women, the following were more common in HSC migrant women: maternal age <20years (0.9 vs 3.7% p<0.001), multiparity (52.2 vs 74.7% p<0.001), BMI ≥25 (38.3% vs 50.1% p<0.001), anaemia (3.5% vs 6.4% p<0.001), tuberculosis (0.2% vs 0.4% p=0.007) and syphilis (0% vs 0.6% p<0.001). Maternal HSC birth was independently associated with poor/no pregnancy care attendance (OR=2.5 95% CI:1.7-3.6), late booking visit (OR=1.3 95% CI:1.1-1.5) and post-term birth (OR=2.5 95% CI:1.9-3.5). Stillbirth (0.6% vs 1.1% p=0.004, OR=1.4 95% CI:0.8-2.4) and birth before arrival (BBA) (0.6% vs 1.4% p<0.001, OR=1.3 95% CI:0.8-2.1) were more common in HSC-born women but not independently associated with maternal HSC birth. However, some risk 52 factors for stillbirth (overweight, age <20 years) and BBA (age <20 years, multiparity) were more common in HSC-born women. Conclusion: These findings suggest a need for targeted strategies to support engagement in pregnancy care among women of refugee background. This would be expected to improve general health and reduce the rate of key poor pregnancy outcomes more common in women of refugee background than in non-refugee migrant women. 1130 – 1140 1120 – 1130 Introduction: Current means of assessing women presenting with suspected preeclampsia using BP and proteinuria are of limited use in predicting ned for imminent delivery. Objectives/ Method/ Design: We undertook a prospective multicentre study to determine diagnostic accuracy of PlGF <5th centile (Triage assay) and other candidate biomarkers in women presenting with suspected pre-eclampsia at 20- 35 weeks’ gestation, in determining need for delivery for pre-eclampsia within 14 days. We calculated ROC curves for predictive potential and undertook principal factor analysis to determine additional predictive ability for biomarker combinations. Results: In 287 women enrolled prior to 35 weeks, ROC area (0.88, SE 0.03) for PlGF <5th centile for pre-eclampsia requiring delivery within 14 days was greater than all other commonly utilised tests (systolic and diastolic BP, urate, ALT), either singly (range 0.58 to 0.68), or in combination (0.69) (p<0.001 for all comparisons), and was greater than that of all other biomarkers; addition of two other biomarker panels (either procalcitonin, nephrin and BNP; or cystatin and PAPP-A) increased ROC area to 0.90 but these biomarkers had limited predictive ability on their own. Conclusion: In women presenting prior to 35 weeks’ gestation with suspected pre-eclampsia, low PlGF has a greater ROC area than other commonly utilised tests. Additional biomarkers add only a small increment to the predictive value of a single PlGF measurement. Only Time Will Tell: The Effect of Extending Dinoprostone Pessary Placement From 12 to 24 Hours on the Need for Transcervical Balloon Catheters Lusink V1*, Usher L1, Day T2 1 The Maitland Hospital, Department of Obstetrics and Gynaecology, Maitland, New South Wales 2 John Hunter Hospital, Maternity and Gynaecology, Newcastle, New South Wales Objective: To examine if a protocol change in February 2013 from 12 to 24 hour dinoprostone pessary placement for cervical ripening reduces the requirement for additional ripening with a transcervical balloon catheter. Methods: Consecutive women undergoing cervical ripening with a dinoprostone pessary were identified from the Obstetrix database before and after a protocol change from 12 to 24 hour placement. With an 80% power and alpha of 0.05, 72 women per group are required to find a reduction in balloon use from 35% to 15%. Data were collected on demographics, transcervical balloon catheter use, syntocinon use, and mode of delivery. Results: We analysed 79 women in the 24 hour and 91 women in the 12 hour group, with an average gestational age at induction of 40 weeks in both groups. There was no significant difference in transcervical balloon use (21% vs 21%; RR, 0.98; CI, 0.55-1.73), syntocinon use (54% vs 61%; RR, 0.88; CI, 0.68-1.15), or vaginal birth (78% vs 70%; RR, 1.12; CI, 0.90-1.31). Conclusions: We have not detected a reduced need for further cervical ripening with a balloon catheter after extending the duration of dinoprostone pessary use from 12 to 24 hours. There is a trend in the 24 hour group towards lower syntocinon use and higher vaginal birth rates. We will continue to collect data with a target of at least 150 women per group to enable detection of a 15% absolute difference in the outcomes of balloon use and vaginal birth. PLGF in Combination with Other Commonly Utilised Tests and Other Biomarkers Predicting Need for Delivery within 14 Days From PreEclampsia in Women Presenting Prior to 35 Weeks Gestation Shennan A1*, Griffin M1, Redman C2, Seed P1, Duckworth S1, Chappell L1 1 Kings College London, United Kingdom 2 Oxford University, United Kingdom 1140 – 1150 The Value of MRI in the Investigation of Pudendal Nerve Entrapment Chow JSW1*, Sachinwalla T1,2, Jarvis SK1, Vancaillie TG1 1 Women’s Health & Research Institute of Australia (WHRIA), Sydney, New South Wales 2 Connect Medical Imaging, Sydney, New South Wales Objective: MRI of the sacral spine and pudendal nerves has been part of the investigations for perineal and pelvic pain at our unit since 2008. This retrospective study examines the correlation of MRI findings of suspected pudendal nerve compression with outcomes of pudendal nerve blocks. Statement of Findings: MRI studies were evaluated for dimensions of the

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