Apoptosis induction by nitric oxide, colchicine and NMDA during mouse post-implantation development
Figure 3. Level of apoptotic cells in 8-day old mouse embryo exposed in utero to 400mM SNP. Magnification: A- 100X, B- 400X
Table 2. Percentage of inviability induced in utero by different concentrations of sodium nitroprusiate (SNP).
Table 3. Induced inviability in 8 and 10 - day old embryos exposed in utero to colchicine.
Table 4. NMDA-induced inviability in 8 and 10 - day embryos exposed in utero.
old embryos inviability was 20.45% and 36.20% for 0.5µg/g and 1µg/g, respectively (Table 4). TUNEL assay showed that 8-day old embryos treated with 0.51 µg/g and 1 µg/g colchicine were
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induced to trigger apoptosis. The embryos treated with higher concentration of colchicine (1 µg/g) showed more extensive positive cells suggesting a higher degree of apoptosis induction (Fig. 4).