Celgene corporation product pipeline review 2015

Global Market Reports and Insight Analytics

Celgene Corporation - Product Pipeline Review - 2015

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Global Market Reports and Insight Analytics

Table of Contents Table of Contents Table of Contents 2 List of Tables 8 List of Figures 8 Celgene Corporation Snapshot 9 Celgene Corporation Overview 9 Key Information 9 Key Facts 9 Celgene Corporation - Research and Development Overview 10 Key Therapeutic Areas 10 Celgene Corporation - Pipeline Review 17 Pipeline Products by Stage of Development 17 Pipeline Products - Monotherapy 18 Pipeline Products - Partnered Products 19 Partnered Products/Combination Treatment Modalities 20 Pipeline Products - Out-Licensed Products 22 Out-Licensed Products/Combination Treatment Modalities 23 Celgene Corporation - Pipeline Products Glance 24 Celgene Corporation - Late Stage Pipeline Products 24 Pre-Registration Products/Combination Treatment Modalities 24 Phase III Products/Combination Treatment Modalities 25 Celgene Corporation - Clinical Stage Pipeline Products 26 Phase II Products/Combination Treatment Modalities 26 Phase I Products/Combination Treatment Modalities 27 Celgene Corporation - Early Stage Pipeline Products 28 Preclinical Products/Combination Treatment Modalities 28 Discovery Products/Combination Treatment Modalities 29 Contact: sales@reportsexpress.com Website: www.reportsexpress.com

Global Market Reports and Insight Analytics Celgene Corporation - Drug Profiles 30 apremilast 30 Product Description 30 Mechanism of Action 30 R&D Progress 30 lenalidomide 33 Product Description 33 Mechanism of Action 33 R&D Progress 33 paclitaxel albumin bound 37 Product Description 37 Mechanism of Action 37 R&D Progress 37 amrubicin hydrochloride 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 azacitidine 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 pomalidomide 45 Product Description 45 Mechanism of Action 45 R&D Progress 45 romidepsin 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 CC-11050 51 Contact: sales@reportsexpress.com Website: www.reportsexpress.com

Global Market Reports and Insight Analytics Product Description 51 Mechanism of Action 51 R&D Progress 51 CC-220 52 Product Description 52 Mechanism of Action 52 R&D Progress 52 cenplacel-L 54 Product Description 54 Mechanism of Action 54 R&D Progress 54 GI-6301 56 Product Description 56 Mechanism of Action 56 R&D Progress 56 mongersen 57 Product Description 57 Mechanism of Action 57 R&D Progress 57 PDA-002 58 Product Description 58 Mechanism of Action 58 R&D Progress 58 spebrutinib besylate 59 Product Description 59 Mechanism of Action 59 R&D Progress 59 AG-221 61 Product Description 61 Mechanism of Action 61 Contact: sales@reportsexpress.com Website: www.reportsexpress.com

Global Market Reports and Insight Analytics R&D Progress 61 CC-223 64 Product Description 64 Mechanism of Action 64 R&D Progress 64 ARRY-382 65 Product Description 65 Mechanism of Action 65 R&D Progress 65 CC-115 66 Product Description 66 Mechanism of Action 66 R&D Progress 66 CC-122 67 Product Description 67 Mechanism of Action 67 R&D Progress 67 CC-90001 69 Product Description 69 Mechanism of Action 69 R&D Progress 69 CC-90002 70 Product Description 70 Mechanism of Action 70 R&D Progress 70 CC-90003 71 Product Description 71 Mechanism of Action 71 R&D Progress 71 CTP-730 72 Contact: sales@reportsexpress.com Website: www.reportsexpress.com

Global Market Reports and Insight Analytics Product Description 72 Mechanism of Action 72 R&D Progress 72 EPZ-5676 73 Product Description 73 Mechanism of Action 73 R&D Progress 73 Stem Cell Therapy for Hematological Malignancies and Non-Malignant Disorders 75 Product Description 75 Mechanism of Action 75 R&D Progress 75 ABI-013 76 Product Description 76 Mechanism of Action 76 R&D Progress 76 Antibody for Oncology 77 Product Description 77 Mechanism of Action 77 R&D Progress 77 AVL-181 78 Product Description 78 Mechanism of Action 78 R&D Progress 78 AVL-192 79 Product Description 79 Mechanism of Action 79 R&D Progress 79 CC-0730671 80 Product Description 80 Mechanism of Action 80 Contact: sales@reportsexpress.com Website: www.reportsexpress.com

Global Market Reports and Insight Analytics R&D Progress 80 CC-2142 81 Product Description 81 Mechanism of Action 81 R&D Progress 81 CC-509 82 Product Description 82 Mechanism of Action 82 R&D Progress 82 CC-539 83 Product Description 83 Mechanism of Action 83 R&D Progress 83 CNX-1351 84 Product Description 84 Mechanism of Action 84 R&D Progress 84 IMiDxl 85 Product Description 85 Mechanism of Action 85 R&D Progress 85 Small Molecules for Cancer and Inflammation 86 Product Description 86 Mechanism of Action 86 R&D Progress 86 Small Molecules for Undisclosed Indication 87 Product Description 87 Mechanism of Action 87 R&D Progress 87 Antibody for Undisclosed Indication 88 Contact: sales@reportsexpress.com Website: www.reportsexpress.com

Global Market Reports and Insight Analytics Product Description 88 Mechanism of Action 88 R&D Progress 88 CC-0739623 89 Product Description 89 Mechanism of Action 89 R&D Progress 89 CC-2141 90 Product Description 90 Mechanism of Action 90 R&D Progress 90 CSC-1 91 Product Description 91 Mechanism of Action 91 R&D Progress 91 Drug to Inhibit Kinase for Inflammation 92 Product Description 92 Mechanism of Action 92 R&D Progress 92 Drugs for Hematology and Oncology 93 Product Description 93 Mechanism of Action 93 R&D Progress 93 EPIpros-1 94 Product Description 94 Mechanism of Action 94 R&D Progress 94 EPIpros-2 95 Product Description 95 Mechanism of Action 95 Contact: sales@reportsexpress.com Website: www.reportsexpress.com

Global Market Reports and Insight Analytics R&D Progress 95 Monoclonal Antibody Conjugate to Inhibit Protein S100-A9 for MDS 96 Product Description 96 Mechanism of Action 96 R&D Progress 96 Small Molecule to Inhibit Brutons Tyrosine Kinase for Inflammation 97 Product Description 97 Mechanism of Action 97 R&D Progress 97 Small Molecules for Inflammation 98 Product Description 98 Mechanism of Action 98 R&D Progress 98 Small Molecules for Inflammation and Cancer 99 Product Description 99 Mechanism of Action 99 R&D Progress 99 Small Molecules for Malaria 100 Product Description 100 Mechanism of Action 100 R&D Progress 100 Celgene Corporation - Pipeline Analysis 101 Celgene Corporation - Pipeline Products by Target 101 Celgene Corporation - Pipeline Products by Route of Administration 103 Celgene Corporation - Pipeline Products by Molecule Type 104 Celgene Corporation - Pipeline Products by Mechanism of Action 105 Celgene Corporation - Recent Pipeline Updates 107 Celgene Corporation - Dormant Projects 140 Celgene Corporation - Discontinued Pipeline Products 142 Discontinued Pipeline Product Profiles 142 Contact: sales@reportsexpress.com Website: www.reportsexpress.com

Global Market Reports and Insight Analytics CC-1088 142 satraplatin 142 Celgene Corporation - Company Statement 143 Celgene Corporation - Locations And Subsidiaries 145 Head Office 145 Other Locations & Subsidiaries 145 Appendix 151 Methodology 151 Coverage 151 Secondary Research 151 Primary Research 151 Expert Panel Validation 151 Contact Us 151 Disclaimer 152

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List of Tables List of Tables Celgene Corporation, Key Information 9 Celgene Corporation, Key Facts 9 Celgene Corporation - Pipeline by Indication, 2015 11 Celgene Corporation - Pipeline by Stage of Development, 2015 17 Celgene Corporation - Monotherapy Products in Pipeline, 2015 18 Celgene Corporation - Partnered Products in Pipeline, 2015 19 Celgene Corporation - Partnered Products/ Combination Treatment Modalities, 2015 20 Contact: sales@reportsexpress.com Website: www.reportsexpress.com

Global Market Reports and Insight Analytics Celgene Corporation - Out-Licensed Products in Pipeline, 2015 22 Celgene Corporation - Out-Licensed Products/ Combination Treatment Modalities, 2015 23 Celgene Corporation - Pre-Registration, 2015 24 Celgene Corporation - Phase III, 2015 25 Celgene Corporation - Phase II, 2015 26 Celgene Corporation - Phase I, 2015 27 Celgene Corporation - Preclinical, 2015 28 Celgene Corporation - Discovery, 2015 29 Celgene Corporation - Pipeline by Target, 2015 101 Celgene Corporation - Pipeline by Route of Administration, 2015 103 Celgene Corporation - Pipeline by Molecule Type, 2015 104 Celgene Corporation - Pipeline Products by Mechanism of Action, 2015 106 Celgene Corporation - Recent Pipeline Updates, 2015 107 Celgene Corporation - Dormant Developmental Projects,2015 140 Celgene Corporation - Discontinued Pipeline Products, 2015 142 Celgene Corporation, Other Locations 145 Celgene Corporation, Subsidiaries 145

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List of Figures List of Figures Celgene Corporation - Pipeline by Top 10 Indication, 2015 11 Celgene Corporation - Pipeline by Stage of Development, 2015 17 Celgene Corporation - Monotherapy Products in Pipeline, 2015 18 Celgene Corporation - Partnered Products in Pipeli

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