This publication articulates and explores the artistic research project, DETOX / Clean it up!, conducted by Rejmyre Art Lab’s Center for Peripheral Studies, an artist-run organization dedicated to long-term, place-based research in the glass factory town of Rejmyre, Sweden. Detox / Clean it up! is an artist-led research that accompanies an environmental remediation project underway in Rejmyre, aimed at addressing the heavy concentrations of pollutants from a 200-year history of industrial glass production. The project enlisted a dozen artists over a two-year period to create works as an official part of the government's pre-study of the contaminated site. The publication explores the conceptual structures and methods deployed in this long-term, site-responsive art engagement from the perspective of the participating artists, Daniel Peltz, as the research leader of the project, and curator, researcher and writer Taru Elfving.