LUMAFLEX
AN EXCLUSIVE INTERVIEW WITH INNOVATOR, CEO & FOUNDER OF LUMAFLEX
DR. DAVID BARZILAI
ON THE COVER FOUNDER AND CEO, BARZILAI LONGEVITY CONSULTING
EDITOR'S TOP PICKS TRENDS, TIPS & INSPIRATION
IRYNA KREMIN REDEFINING BEAUTY, WELLNESS, AND LONGEVITY
EDITOR’S LETTER
Personal Message from Our Editor-in-Chief
We Highlight Remarkable Individuals Making a Positive Impact in Our Community
Get to Know The Talented Individuals Behind The Scenes
An exclusive interview with Founder and CEO, Barzilai Longevity Consulting Dr. David Barzilai
An Exclusive Interview with The Founder of INNOCOS Iryna Kremin
Your Go-To Source for Fashion Trends, Tips, and Style Inspiration
An exclusive interview with Founder and CEO, 1r Agency Shelly Socol TRENDING
Stem Cell Mentoring with Dr. Nathan Newman
Welcome to this special edition of Red Hot Monde Magazine, dedicated to the INNOCOS Longevity Summit in Miami—an event that brings together the brightest minds in beauty, wellness, and longevity for three days of transformative learning, networking, and innovation. At the heart of this issue is a woman who truly embodies the spirit of longevity, reinvention, and beauty from the inside out—Iryna Kremin, the visionary founder of INNOCOS. As she celebrates her 60th birthday, she defies every conventional notion of aging, looking not only fabulous but exuding the kind of energy and confidence that comes from a deep understanding of wellness, selfcare, and purpose-driven leadership. This issue is packed with insightful interviews, expert perspectives, and behind-the-scenes access to the INNOCOS Miami experience. We explore the latest advancements in longevity, the secrets behind aging gracefully, and the innovations shaping the future of beauty and health. From groundbreaking skincare technologies to holistic wellness practices, this summit is a testament to how we can redefine beauty at every stage of life. Iryna’s journey is one of passion and perseverance. She has built a global platform that connects thought leaders and disruptors in the industry, creating a space where science meets beauty and longevity. Her ability to stay ahead of trends while maintaining an effortless, radiant presence is nothing short of inspiring. So, what’s her secret? You’ll have to dive into this issue to find out! Join us as we celebrate the power of longevity, the future of beauty, and the extraordinary women who are leading the way. Whether you’re attending the summit or following along through these pages, this issue is your front-row seat to the conversations shaping the future of wellness. Here’s to beauty without limits and a future where we redefine aging on our own terms.
IRYNA VOSKERICIAN Publisher & Editor-in-Chief
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An inaugural faculty member and Trustee at the Geneva College of Longevity Science, Dr. Barzilai leverages his PhD in Health Services Research to drive precision medicine innovations. He integrates the latest scientific breakthroughs with personalized strategies to extend healthspan and advance the science of aging. A Diplomate of the American Board of Lifestyle Medicine, he applies a comprehensive data-driven approach encompassing nutrition, physical activity, sleep, stress management, and emerging therapeutics.
Through Barzilai Longevity Consulting (agingdoc.com), he collaborates with clients to design tailored longevity plans, translating complex research into actionable strategies. Known as @agingdoc1 on X (formerly Twitter), he engages a global audience of academics, scientists, and health leaders, sharing insights and fostering discussions on aging and longevity medicine.
Dr. David Barzilai, MD, PhD, MBA, MS, DipABLM, FAAD, is a globally recognized longevity medicine physician, and consultant specializing in evidence-based healthspan optimization best practices. As the founder and CEO of Barzilai Longevity Consulting (Healthspan Coaching LLC), he helps individuals and organizations implement cutting-edge longevity science to enhance well-being, performance, and vitality.
Barzilai Consulting is your indispensable scientific partner for premium evidence-based healthy aging practices.
Beyond public engagement, Dr. Barzilai advises individuals, corporations, and healthcare organizations on longevity-focused strategies, workforce well-being, and executive health optimization. As a sought-after speaker, he delivers keynotes at major scientific and clinical conferences worldwide. His expertise, thought leadership, and commitment to evidence-based innovation continue to shape the future of longevity medicine.
Q: You have an impressive multidisciplinary background—MD, PhD, DipABLM, and more. What inspired your deep dive into longevity science, and how did your career evolve to focus on healthspan optimization?
A: The inspiration for diving into longevity science emerged from my early life experience with severe asthma. Spending countless nights in hospital wards, tethered to machines and unable to participate in the activities of my peers, gave me an early and profound understanding of health’s fragility—and the necessity of a proactive
approach to lifelong well-being. This realization shaped my approach to medicine, leading me to pursue an MD/ PhD at Case Western Reserve. My doctoral research in Health Services Research provided a strong foundation in scientific inquiry and evidence-based problem-solving. These skills now underpin my work in precision medicine, where I develop personalized frameworks for optimizing health. Understanding that true longevity is driven not just by genetics or medical advances but by the daily choices we make, I became a Diplomate of the American Board of Lifestyle Medicine, ensuring that evidence-based lifestyle strate-
gies remain central to my approach. Now, as a longevity physician and consultant, I bring together these diverse threads—scientific rigor, clinical expertise, and advanced insight into lifestyle medicine—to offer clients a truly personalized protocol for elevating their healthspan. Over the years, my work evolved to integrate the highest standards of modern medicine, from precision diagnostics and proactive surveillance to cutting-edge preventative strategies, ensuring optimal health at every level. At the same time, my deep engagement with aging science led me to track and translate emerging breakthroughs into actionable interventions for my clients. What began as a personal drive to overcome health limitations has developed into a lifelong pursuit of extending not just lifespan, but healthspan—helping individuals sustain peak vitality, resilience, and an uncompromising quality of life for decades to come.
Q: Many people conflate lifespan with healthspan. How do you define the distinction, and why is healthspan optimization more critical than ever?
A: Lifespan is simply the number of years you live, whereas healthspan is the number of years you remain vibrant, functional, and free from serious disease or disability. Imagine two individuals who both live to 90. One spends the last decades battling chronic illness, while the other remains physically active and mentally sharp almost until the end. Both achieved the same lifespan, but their healthspans could not be more different.Healthspan optimization isn’t just about preventing disease—it’s about ensuring that a longer life is one worth living. Advances in geroscience, precision medicine, and longevity therapeutics allow us to delay age-related decline, compress morbidity, and ensure extended longevity remains a period of thriving, not just surviving. By integrating lifestyle medicine with cutting-edge diagnostics and proactive interventions, we no longer have to choose between lifespan and healthspan—we can achieve both.
Q: As a pioneer in longevity medicine, what are the most exciting scientific breakthroughs on the horizon that could significantly extend our healthspan?
A: The field of longevity science is advancing at an unprecedented pace, with dozens of promising breakthroughs that
could redefine how we approach aging and healthspan extension. While there are many exciting developments, here are just a few that stand out:
Epigenetic reprogramming is one of the most exciting frontiers in longevity science. Research shows that specific Yamanaka factors—Oct4, Sox2, and Klf4—can reverse aspects of cellular aging while preserving cell identity. In one study, this approach restored vision in aged mice by rejuvenating damaged retinal cells, suggesting a potential breakthrough in treating age-related degeneration. While this is still in early stages for human application, if safely translated, it has the potential to revolutionize regenerative medicine, offering new therapeutic avenues for neurodegeneration, muscle loss, and organ deterioration.
Another area already being explored in clinical settings is stem cell therapy for tissue regeneration. Stem cell exhaustion is a fundamental hallmark of aging, and replenishing or rejuvenating stem cell populations holds promise for restoring function in aging tissues. Mesenchymal and hematopoietic stem cell infusions, in particular, are being studied for their ability to reduce inflammation, enhance immune resilience, and promote tissue repair. Clinical trials have shown encouraging results in improving frailty, neurodegeneration, and cardiovascular health, but widespread clinical adoption will require continued refinement, standardization, and longterm outcome data to guide their optimal use. Additionally, AI-driven precision medicine is revolutionizing the way we approach longevity interventions. AI-powered models are now capable of analyzing vast multi-omics datasets—integrating genomics, transcriptomics, proteomics, and real-time functional biomarkers—to assess biological aging and predict individual disease risks with far greater accuracy than traditional models. These insights are allowing for the development of truly personalized health strategies, where interventions are tailored not by arbitrary chronological age but by an individual's specific aging trajectory at the cellular and systemic level.
Beyond these examples, a growing pipeline of gerotherapeutics—pharmacological interventions targeting the biology of aging—is being evaluated for its translational potential. From mTOR inhibitors to mitochondrial therapy, senolytics, and autophagy modulators, these therapies are at different stages of clinical validation, but they represent a critical shift from simply managing age-related diseases to directly addressing the mechanisms that drive aging itself.
Already have a longevity provider? We offer essential, objective scientific support to elevate your health practices. We provide highly tailored, personalized health services, designed to seamlessly complement your existing longevity team.
Q: Precision medicine and AI are revolutionizing healthcare. How do these technologies intersect with your work in longevity, and what role will they play in the future of aging?
A: Precision medicine and AI allow us to move from broad guidelines to hyper-personalized strategies. Instead of standard “eat healthier, exercise more” advice, we integrate multi-omic data—genomics, proteomics, metabolomics— plus real-time metrics like CGM data or heart rate variability from wearables. AI algorithms then sift through these datasets to pinpoint early indicators of metabolic imbalance or subtle shifts in inflammation.
This matters because aging is not a one-sizefits-all process. Some individuals might be more prone to neurodegenerative pathways, while others have higher cardiovascular risks. The future, as I see it, is a dynamic interplay between predictive analytics and continuous assessment, adjusting interventions—be they dietary tweaks, supplement regimens, or advanced therapeutics—in real time. AI-driven models will increasingly guide us on when to intensify certain treatments or pull back, ultimately offering a more fluid and proactive approach to aging.
Q: Lifestyle medicine is a key pillar of your approach. What are the most impactful yet underrated lifestyle interventions people should adopt for longevity?
A: When we think about longevity, diet, exercise, and sleep take center stage. But some of the most powerful factors influencing how we age are often overlooked.
Strength training is a critical but often neglected factor. While aerobic exercise is widely emphasized, studies confirm that muscle strength is an independent predictor of longevity. Aging-related muscle loss accelerates metabolic dysfunction, frailty, and osteoporosis, yet just two weekly strength sessions can enhance insulin sensitivity, mitochondrial function, and neuromuscular coordination—dramatically lowering disease risk and preserving mobility.
Then there’s the hidden risk of prolonged sitting. Many assume regular exercise offsets sedentary time, but extended sitting—even for those who work out—disrupts glucose metabolism, endothelial function, and promotes chronic inflammation. Simply standing, stretching, or walking for a couple of minutes every 30 to 60 minutes can counteract these effects and meaningfully reduce long-term risk.
Social connection is rarely considered a med-
INTERVIEW DR. DAVID BARZILAI
ical intervention, yet strong relationships are as crucial to longevity as quitting smoking. Research shows that people with meaningful social ties have significantly lower mortality risk, while chronic loneliness drives inflammation, cardiovascular disease, and cognitive decline. Despite this, social health remains an afterthought in most longevity discussions. Making time for deep, consistent engagement— whether through community, friendships, or purpose-driven relationships—is one of the most underrated longevity strategies. Ultimately, longevity isn’t just about the obvious health pillars—it’s about the small, overlooked habits that compound over time. Prioritizing strength training, breaking up sedentary time, and maintaining social connection may seem simple, but they are among the most powerful and science-backed ways to extend both lifespan and healthspan.
Q: How do you balance evidence-based interventions with emerging longevity therapeutics, and what should people be cautious about when navigating this rapidly evolving field?
A: Balancing evidence-based interventions with emerging longevity therapeutics requires a nuanced, individualized approach. Many promising agents—such as rapamycin and SGLT2 inhibitors—show strong mechanistic rationale and encouraging preclinical or early clinical data. However, the reality is that many of these therapies remain experimental, and while they may offer potential benefits, they also come with uncertainties, including unknown long-term effects and individual variability in response.
Aging itself carries inherent risks, and for some individuals, taking on a measured level of uncertainty may be a reasonable choice, particularly when weighed against the downsides of aging-related decline. However, these choices should never be made lightly. The key is a highly personalized, data-driven, and well-informed approach—one that aligns with an individual’s goals, risk tolerance, and priorities while maintaining transparency about both potential benefits and unknowns.
My guiding principle is to apply strong mechanistic rationale, layered with emerging human data, before considering any therapy. I encourage clients to critically assess interventions by asking:
Is there a compelling scientific basis? Understanding the mechanisms behind a therapy helps determine its plausibility. What does early human data suggest? Preclinical findings don’t always translate to humans, so assessing safety and initial efficacy in clinical studies is essential.
How will my response be measured? Without tracking biomarkers or clinical endpoints, it’s impossible to assess whether an intervention is working as intended. It’s also crucial to recognize that no cutting-edge intervention can replace the foundational pillars of longevity—nutrition, exercise, sleep, and emotional well-being. While it’s reasonable for some to explore emerging therapies, it should be done with clear-eyed awareness of both potential benefits and limitations. A longevity strategy should be objective, transparent, and tailored to the individual, ensuring that every decision is both informed and intentional.
Q: Many people associate aging with inevitable decline. How does your precision medicine approach to healthspan optimization challenge that notion?
A: Aging is often perceived as an unavoidable deterioration, but modern longevity science is rewriting this narrative. We now understand aging as a dynamic, modifiable process shaped by key biological mechanisms.
The Hallmarks of Aging, first identified in 2013 and expanded in 2023, provide a framework for understanding why we age—from genomic instability and mitochondrial dysfunction to chronic inflammation and cellular senescence. Crucially, research shows these pathways can be actively modulated, slowing or even partially reversing aspects of aging.
Rather than managing decline, my approach focuses on actively optimizing longevity—putting individuals in control of their biological trajectory. Precision longevity medicine combines early detection, targeted interventions, and continuous monitoring to create proactive, highly individualized strategies.
For example, individuals with an APOE4 genetic predisposition to Alzheimer’s face a higher risk of cognitive decline, but risk is not destiny. By optimizing ApoB levels, maintaining metabolic flexibility through structured exercise and sleep protocols,
and incorporating tailored dietary interventions such as the MIND diet or other neuroprotective diets personalized to the individual, we can significantly modify their risk profile. Specialized workout protocols designed to enhance neuroplasticity and cardiovascular efficiency—such as zone 2 training and high-intensity interval training (HIIT)—further support long-term cognitive resilience. Surveillance of key biomarkers ensures we adapt interventions in real time, staying ahead of potential risks. Emerging strategies, including cognitive training and metabolic therapies, may offer additional neuroprotection. For other clients, heart disease or cancer may be the primary areas of concern, requiring a similarly personalized approach to risk mitigation and early intervention.
Biomarker monitoring, early detection, and prevention is central to this approach. Tracking metabolic markers like fasting glucose, fasting insulin, and postprandial glucose excursions allows for precise, data-driven adjustments. Continuous glucose monitors (CGMs) provide real-time feedback, helping individuals refine nutrition and activity based on their unique glycemic responses. A 2015 Weizmann Institute study demonstrated that glycemic reactions to identical foods vary significantly between individuals, reinforcing the value of a personalized approach.
The power of precision medicine lies in its adaptability. Interventions can be as simple as routine bloodwork monitoring or as advanced as integrating wearables, real-time biometrics, and AI-driven analytics. By tailoring strategies to each individual’s goals and values, we turn longevity optimization into a practical, sustainable, and deeply personalized pursuit.
Q: You emphasize a data-driven approach to aging. What are the key biomarkers or diagnostic tools that provide the most valuable insights into a person’s longevity potential?
A: A data-driven approach to aging allows us to move beyond guesswork and personalize interventions based on measurable insights. The key is finding the right balance—some people prefer a few essential markers, while others want deep, continuous tracking. It all depends on individual goals, bioindividuality, and how far someone wants to go.
Metabolic health is foundational, and early signs of dysfunction often show up in
markers like fasting insulin, HOMA-IR, and postprandial glucose levels—well before fasting glucose or A1C. Advanced lipid panels, including ApoB and lipoprotein(a), provide a clearer picture of cardiovascular risk than standard cholesterol tests, helping to fine-tune prevention strategies.
Inflammation is another key driver of aging, and markers like high-sensitivity CRP, IL-6, and TNF-α offer insights into chronic low-grade inflammation that can accelerate disease. Immune cell profiling can further reveal hidden imbalances tied to “inflammaging,” helping to guide targeted interventions.
Functional assessments are some of the strongest predictors of longevity. VO₂ max correlates with overall health and resilience, grip strength reflects vitality, and gait speed can predict long-term mobility and morbidity risk. A simple DEXA scan reveals body composition, including visceral fat, which plays a major role in metabolic and cardiovascular health.
Emerging tools like epigenetic clocks estimate biological age based on DNA methylation patterns. While they are still
being validated and should not be used as stand-alone diagnostics, they may serve as helpful adjuncts when considered alongside traditional and functional markers of health.
Wearables and real-time monitoring have made longevity tracking more accessible than ever. CGMs help personalize nutrition by showing real-time glucose responses, while HRV tracking provides insight into stress, recovery, and nervous system balance. These tools create a continuous feedback loop, allowing for small adjustments that can make a big impact over time.
Of course, these are just a few examples, and the right approach depends on the individual. Not everyone needs to track everything, and longevity optimization should never feel overwhelming. The key is using data to guide smarter, more effective choices—whatever that looks like for each person.
Q: Sleep, stress, and metabolic health are often overlooked in longevity discussions. How do these factors influence aging, and what strategies do you recommend for op-
A: Sleep is a cornerstone of longevity, yet inadequate or poor-quality rest disrupts essential processes like growth hormone release, immune function, and metabolic regulation. Over time, chronic sleep debt compounds the risk of obesity, diabetes, and cognitive decline. Simple but powerful tools—such as sleep trackers, consistent bedtime routines, and stress-reduction techniques like guided breathing—can be transformative, helping to support deep, restorative sleep and optimize long-term health.
Stress is another silent driver of accelerated aging. Chronic psychological stress fuels cortisol spikes and inflammatory cytokine production, creating a biochemical environment that erodes resilience and increases disease burden. This isn’t just about feeling overwhelmed—prolonged stress actively reshapes the body’s aging trajectory. That’s why I emphasize strategies like mindfulness, HRV biofeedback, or therapy to build emotional resilience. These are not optional wellness trends; they are fundamental to maintaining both healthspan and lifespan.
INTERVIEW DR. DAVID BARZILAI
Metabolic health is perhaps the most underestimated determinant of aging. Insulin resistance, elevated fasting glucose, and chronic inflammation quietly fasttrack biological decline, damaging blood vessels and accelerating organ deterioration. Addressing these early warning signs is critical. I often implement a multi-pronged approach—refining dietary strategies like time-restricted feeding, prescribing targeted exercise protocols to enhance insulin sensitivity, and, in specific cases, incorporating pharmacological support such as SGLT2 inhibitors or metformin when risk markers emerge.
These “silent accelerators” of aging—sleep dysfunction, chronic stress, and metabolic dysregulation—are among the most powerful levers for longevity. Addressing them with precision can yield benefits as profound as any cutting-edge therapy on the horizon.
Q: There is growing interest in longevity-focused executive health programs. How do high-performance individuals, such as CEOs and entrepreneurs, approach aging differently, and what unique challenges do they face?
A: My experience with high-performance individuals—CEOs, entrepreneurs, and top executives is they are driven to push limits, they demand peak cognitive function, and expect immediate, tangible results. But this relentless drive often comes at a cost. Chronic stress, erratic schedules, and constant overcommitment create a silent but powerful drag on their biology, accelerating aging in ways they may not immediately recognize.
That’s where precision-driven longevity strategies come in. I design executive health programs that fit seamlessly into demanding lives, leveraging efficiency and data-driven feedback to optimize results. Strength training or high-intensity interval workouts are structured into short, high-impact sessions that maximize benefits in minimal time. Continuous glucose monitors and HRV trackers provide real-time insights, allowing busy professionals to fine-tune their habits with the same precision they apply to their business strategies. Accountability and feedback loops ensure that progress is both measurable and motivating.
For high performers, longevity isn’t just about adding years—it’s about sustaining peak mental clarity, resilience, and energy for the long game. The best leaders optimize not only their companies but also their own biology, treating health as the ultimate investment in long-term success.
Barzilai Longevity Consulting, led by CEO Dr. David Barzilai, offers personalized one-on-one consultations focused on optimizing health and longevity. Through direct, ongoing engagement, the consultancy tailors science-backed strategies to each individual’s unique needs. For more information, visit agingdoc.com
Q: Through agingdoc.com and your social media presence, you actively engage a global audience on longevity science. What are the biggest misconceptions people have about aging, and how do you address them?
A: One of the biggest misconceptions about aging is that it’s primarily dictated by genetics— an unchangeable script written in our DNA. In reality, only about 5-20% of longevity has been demonstrated to be genetic; the vast majority is shaped by our environment and how our genes interact with it through epigenetics. This means that the way we eat, move, sleep, and manage stress profoundly impacts our long-term health and resilience. Scientific research has shown that these factors influence gene expression, regulate inflammation, and enhance cellular repair, helping to slow the processes that drive age-related decline. By making the right interventions, we can dramatically shift the trajectory of how we age—maintaining strength, cognitive clarity, and vitality for far longer than previously thought possible.
Another common myth is the idea that longevity is either entirely lifestyle-driven or dependent solely on cutting-edge medical interventions, when in reality, both are essential—but must be individualized. While optimizing foundational habits like diet, exercise, sleep, and stress management remains the most powerful way to extend healthspan, there is a critical role for targeted supplementation and pharmaceutical strategies. However, these interventions must be carefully tailored based on an individual’s biomarkers, metabolic profile, and personal risk factors. There is no universal formula for longevity; what works for one person may be ineffective—or even counterproductive—for another. Science-driven longevity is about precision, not guesswork, leveraging the right tools at the right time based on a person's unique biology and goals.
Finally, many assume that if they “feel fine,” they have no underlying risks. But conditions like insulin resistance, chronic inflammation, and early vascular dysfunction often develop silently, long before symptoms arise. This is where biomarker tracking becomes invaluable—allowing for early detection and precise, personalized interventions. The goal isn’t just to prevent disease but to optimize healthspan—the years of life lived in peak physical and cognitive function. By integrating cutting-edge science with a proactive, highly personalized approach, we can move beyond simply extending lifespan and instead maximize the quality, performance, and vibrancy of those years.
Q: You are a faculty member and Trustee at the Geneva College of Longevity Science. How do you see the academic landscape evolving to integrate longevity science into mainstream medicine?
A: For too long, longevity science was seen as theoretical—fascinating but not actionable. That is rapidly changing. The growing recognition that aging itself is the strongest risk factor for nearly every chronic disease has triggered a shift in medicine. Leading institutions are beginning to integrate geroscience into medical education, moving beyond the outdated, disease-by-disease approach toward a systems-level understanding of aging biology.
In the next decade, medical training will evolve to include longevity-focused coursework, equipping physicians to intervene earlier using biomarkers, epigenetic analysis, and metabolic assessments as routine clinical tools. Residency programs will incorporate precision longevity medicine, training doctors to enhance healthspan, not just delay disease.
True progress in longevity medicine requires breaking down silos between physicians, aging biologists, biotech innovators, and public health leaders. Advancing the field demands not just scientific discovery but strict validation—ensuring new therapies and diagnostics meet the highest clinical standards. Public trust is easily undermined by exaggerated anti-aging claims, making transparency and data-driven communication critical. Longevity science must be built on proven, peer-reviewed research, not hype.
Q: What is the single most important investment one can make for maximum healthspan and longevity?
A: The greatest investment in longevity isn’t a single intervention—it’s a strategic, evidence-based approach tailored to your unique biology. While optimizing lifestyle fundamentals is essential, true longevity mastery goes beyond conventional health advice, integrating cutting-edge diagnostics and precision interventions to sustain peak health and performance for as long as possible.
Muscle mass, cardiovascular capacity, and metabolic flexibility are among the strongest predictors of long-term vitality. Strength training and targeted aerobic exercise aren’t just about fitness—they preserve mobility, cognitive sharpness, and overall resilience. Nutrition must be personalized, structured to stabilize glucose, regulate inflammation, and optimize metabolic health. High-quality sleep is just as critical, supporting memory consolidation, immune function, and physical recovery. Proactive stress
management isn’t a luxury—it’s a necessity for slowing biological aging and maintaining longterm well-being.
What sets true longevity optimization apart is precision. Advanced biomarker tracking, early screening, and real-time metabolic assessments allow for highly targeted interventions that evolve with you. This isn’t about guesswork—it’s about leveraging the most advanced tools available to refine and personalize your health strategy over time.
Longevity is a lifelong practice. Set clear goals, track key metrics, and refine your approach based on real data. Stay proactive, stay informed, and invest in the latest science. Thriving isn’t about perfection—it’s about making the smartest, most effective choices for a life of strength, vitality, and purpose.
Q: Looking ahead, what is your ultimate vision for longevity medicine, and how do you hope your work will contribute to reshaping human health and aging?
A: I aspire to a future where “aging” is treated as a dynamic, modifiable process—a future in which it’s routine for people to enjoy high-level physical and cognitive function well past traditional retirement ages. No one would wait for a heart attack or diabetes diagnosis to pivot their lifestyle; they’d be continuously monitoring and adjusting decades beforehand.
At Barzilai Longevity Consulting, our longterm mission is to bridge the gap between leading-edge science and day-to-day health practices—making personalized, data-driven longevity strategies accessible. On a broader scale, I hope my work and educational roles help reframe the conversation around aging from an inevitable decline to a period of rich possibility. If we manage to compress morbidity and extend the years of vitality for millions, then we’ve truly reshaped human health and aging for the better.
THESE RESPONSES SHOWCASE DR. BARZILAI’S DISTINCTIVE BLEND OF PERSONAL INSIGHT, CUTTING-EDGE CLINICAL EXPERTISE, AND A VISIONARY APPROACH TO LONGEVITY MEDICINE. TAILORED FOR AN AUDIENCE SEEKING THE HIGHEST STANDARD OF EVIDENCE-BASED, PERSONALIZED STRATEGIES TO EXTEND HEALTHSPAN, HIS PERSPECTIVE IS BOTH INSIGHTFUL AND FORWARD-THINKING. EXPLORE HIS PROFESSIONAL BACKGROUND HERE: HTTPS://WWW.LINKEDIN.COM/IN/ AGINGDOC & EXPLORE BARZILAI LONGEVITY CONSULTING (HEALTHSPAN COACHING LLC): AGINGDOC.COM
LONGEVITY ISN’T ABOUT A SINGLE MAGIC BULLET—IT’S A STRATEGIC, PERSONALIZED APPROACH THAT INTEGRATES LIFESTYLE, DIAGNOSTICS, AND PRECISION MEDICINE TO SUSTAIN PEAK HEALTH AND PERFORMANCE.
INNOCOS has become a premier platform for innovation in beauty, wellness, and longevity. What inspired you to create this global summit, and how has the mission evolved over the years?
We launched INNOCOS 15 years ago because we saw a gap. The beauty industry was moving fast—innovation cycles were rapid, consumer preferences were shifting constantly, and there wasn’t a place for top-level leaders to come together, share their successes and failures, and truly learn from one another. We wanted to create a space where people could connect beyond the surface, in an intimate setting that fostered real conversations. What started as a European event quickly gained momentum. We expanded into the US, UAE, and Asia, and over the years, our focus has evolved. We’ve gone from beauty to wellness, and now to longevity— which we believe is the future of beauty. Longevity isn’t a passing trend; it’s about redefining beauty as healthspan, vitality, and aging well.
The upcoming INNOCOS Longevity Miami Summit & Awards brings together thought leaders
in beauty and longevity. What makes this year’s event particularly groundbreaking?
This is the first event of its kind bringing together beauty brands, retailers, longevity clinics, wellness centers, and health institutes under one roof. We’re creating a space where beauty and health intersect—because that’s where the future is. We want to break down silos, foster collaborations, and spark innovations. We’re not just facilitating conversations; we’re helping build the future of this industry. We also have the Wellness & Longevity CHOICE Awards, which celebrate brands leading the charge in this space—bringing together science, beauty, and wellness in ways we haven’t seen before.
You’ve attended industry conferences worldwide. What distinguishes INNOCOS from other events in the beauty and wellness space?
THE BEAUTY INDUSTRY IS MOVING BEYOND AESTHETICS—UNDERSTANDING EPIGENETICS, INFLAMMATION, AND CELLULAR REPAIR IS BECOMING ESSENTIAL.
Iryna Kremin
Honestly, INNOCOS feels like home. I’ve been to so many conferences where you network non-stop, and by the end of the day, you feel drained. At INNOCOS, it’s different. You walk in, and you’re part of a community. There’s this relaxed, almost family-like
atmosphere. We bring in world-class speakers, but we also prioritize connection. We build in time for networking, fun activities, and even games. We don’t take ourselves too seriously, and that’s what makes the magic happen—it’s where the best ideas and partnerships are born. We understand that the best deals and collaborations happen when people feel comfortable and inspired.
You recently turned 60 and have mentioned that 60s are the new 40s. You look fantastic! How has your personal perspective on aging influenced your approach to beauty and wellness?
It actually started when I turned 50. I remember feeling uneasy about that number. Aging made me think of frailty, slowing down, losing style—and I didn’t like that image. But then I thought, I can’t control the number, but I can control how I look and feel. That was my turning point. I started diving into longevity science, reading books, listening to podcasts, and experimenting with my own lifestyle. Now, I don’t care about my chronological age—it’s my biological age that matters. My last test showed I’m 12 years younger biologically, and I feel it every day. Longevity is not just about living longer; it’s about feeling amazing while you do it. Strength training, aerobic exercise, quality sleep, and stress management are non-negotiables for me. It’s all about energy, vitality, and mindset.
Iryna Kremin is a passionate connector and innovator in the beauty and wellness industry, celebrated for her vibrant personality and her belief in the power of heartfelt, human connections.
As the founder of INNOCOS, Iryna has established a highly curated network of leaders in health, beauty, and wellness, dedicated to helping executives connect, advance their careers, and expand their knowledge. INNOCOS offers both online and, above all, face-to-face platforms that facilitate the sharing of educational and disruptive content while creating unforgettable experiences.
Over the past decade, Iryna has created unique events that blend innovation, wellness, and meaningful networking. INNOCOS has journeyed through the creative capitals and resorts of Europe, the USA, the Middle East, and Asia, uniting industry leaders who share a passion for beauty, wellness, and longevity.
With your studies at the Geneva College of Longevity Science, how do you see longevity science reshaping the beauty industry?
’ve been obsessed with longevity for the past 6-8 years, reading everything I could find and attending biohacking events. But there’s so much conflicting information. Even scientists disagree on certain things, like biological age markers. That’s why I joined Geneva College of Longevity Science. I needed a system to fill in the gaps and understand the science deeply. It’s been eye-opening. I’m learning biology on a whole new level. This knowledge is helping me not only personally but also professionally—it elevates our Wellness & Longevity CHOICE Awards and the conversations we facilitate at INNOCOS. The beauty industry is moving toward longevity. It’s not just about appearance anymore; it’s about cellular health and performance. Understanding epigenetics, inflammation, and cellular repair is becoming essential.
What do you think are the biggest myths about aging, and how can the beauty and wellness industries shift the narrative?
The biggest myth is that aging equals decline. That’s outdated. Aging can mean thriving. The beauty industry is already shifting from covering up imperfections to promoting skin health, self-care, and mental wellness. Gen Z and Gen Alpha are driving this, demanding transparency and authenticity. We need to keep evolving that message: Beauty is health. Longevity is beauty. Aging is not something to fear; it’s something to optimize.
The intersection of longevity, wellness, and beauty is rapidly evolving. What scientific breakthroughs or trends do you believe will define the industry in the next decade?
The future is science-driven and personalized. Biotechnology is transforming skincare—we’re seeing synthetic peptides, exosomes, and miniproteins that work on a cellular level. Adaptogens, neurocosmetics, and microbiome-friendly products are addressing the mind-skin connection. Skincare is no longer just topical; it’s internal, emotional, and biological. We are also seeing makeup and fragrances incorporating functional benefits—like calming scents that reduce stress.
If you could give one longevity and beauty tip that you swear by, what would it be?
Exercise. Strength training and aerobic exercise. It impacts everything—digestion, sleep, mood, and cellular health. Move your body every day.
What is a personal wellness ritual you cannot live without?
Meditation. I thought I couldn’t do it for years. Then I read Emily Fletcher’s book “Stress Less, Accomplish More.” Now I meditate 15-20 minutes, twice a day. It keeps me focused and calm. It helps me to live every day intentionally and not reactively. When I skip it, I feel off-balance.
Finally, what does beauty mean to you at this stage in your life and career?
Beauty is harmony. It’s inner and outer balance. From a young age, I saw beauty as the opposite of war. If we focused more on beauty—in art, people, and nature—we’d have less conflict. Beauty is a positive force that brings peace and joy.
Embrace the perfect blend of comfort and style with a velvet midi dress that feels as soft as it looks. Tall boots make a bold statement, while colorful stud earrings and a bracelet provide a playful, personal touch. The leather bag keeps the look grounded and sophisticated, making this Valentine's Day style chic and effortlessly cool.
Let love shine through in a beautiful slit gown that shows off your elegance and charm. Pair it with soft sandals that complement the gown's flow, and add a stunning statement necklace and earrings for a touch of sparkle. A sequined shoulder bag provides the perfect contrast, and a heart-shaped bangle completes your look with romantic flair.
Embrace Valentine's Day in a chic white midi dress, paired with bold red slingback pumps for a pop of passion. Add a touch of timeless class with delicate pearls, and finish the look with a matching red shoulder bag for that perfect, coordinated Valentine's Day vibe. Simple, elegant, and irresistibly stylish.
Turn heads in a fiery red crepe gown, effortlessly paired with crisp white leather pumps that balance out the boldness. Statement earrings add just the right amount of drama, while layers of delicate bracelets create a chic, stacked effect. A minimalist clutch bag in a complementary tone keeps the focus on the gown, allowing you to own the night in style and grace.
Q: Your journey into red light therapy started from personal adversity. How did that experience shape your mission with Lumaflex?
A: My journey into red light therapy (RLT) wasn’t about business—it was about survival. As a competitive athlete, I spent years pushing my body to its limits in rugby, CrossFit, and boxing. That came at a cost—shoulder injuries, a knee injury from Olympic lifting, and chronic pain. Like many athletes, I became dependent on painkillers just to keep going.
The biggest wake-up call came when I was diagnosed with a brain tumor caused by repeated head trauma in boxing. It was a terrifying realization—everything I had built could be gone in an instant. I was forced to completely rethink my approach to recovery, healing, and performance. That’s when my wife introduced me to red light therapy. At first, I was skeptical, but the results were undeniable. My pain decreased, my recovery time improved, and my overall health transformed. It was like discovering a missing piece of the puzzle.
That moment changed everything for me. I knew I had to bring this technology to athletes, fitness professionals, first responders, and everyday people who are suffering from pain and injuries. That’s what led me to create Lumaflex, a portable, flexible, and waterproof red light therapy device that makes natural healing accessible to all.
ABOUT US
Lumaflex is the leading provider of advanced red light therapy devices engineered to supercharge the body, boost sports performance, and accelerate recovery. With a mission to make red light therapy a daily wellness habit, Lumaflex serves as your on-the-go wellness companion.
Q: Boxing and competitive sports demand resilience. How did your mindset as an athlete influence your approach to entrepreneurship?
A: Training and competing as an amateur boxer shaped everything about how I approach business and entrepreneurship.
Boxing isn’t just about throwing punches—it’s about strategy, resilience, and adapting under pressure. You take hits, you get knocked down, but you always get back up.
I have immense respect for professional fighters like Tyson Fury and Zhang Zhilei. They are warriors, coming from humble beginnings, grinding their way to the top. That struggle, that relentless drive to succeed, is something I deeply relate to and emulate in my own career.
That’s why I started White Collar Fight Night (WCFN)—an event that gives business professionals the chance to step into the ring, face their fears, and push themselves beyond their limits. Just like in boxing, the lessons of persistence, discipline, and resilience directly apply to business, leadership, and life.
The same mentality applies to growing Lumaflex—I face challenges head-on, adapt, and keep moving forward.
Q: Overcoming a brain tumor is life-changing. How did that experience redefine your outlook on health, wellness, and innovation?
A: When you’re an athlete, you feel invincible— until you’re not. My brain tumor diagnosis was a wake-up call that reminded me how fragile life is.
I realized that many injuries, chronic pain, and health setbacks are preventable—if you have the right tools and knowledge. But too many people rely on pharmaceuticals, surgeries, and outdated treatments instead of exploring natural, science-backed solutions.
That’s when I committed myself to innovation— to not only healing myself but creating a product that could help others. Lumaflex was born out of that mission—to provide a non-invasive, effective, and easy-to-use recovery tool that fits into anyone’s lifestyle.
I learned that adversity can either break you or push you to innovate—I chose the latter.
Q: Lumaflex is the world’s first FDA-cleared, portable, and waterproof RLT device. What was the biggest challenge in bringing this innovation to market?
A: Education.
The biggest challenge wasn’t just developing the technology—it was getting people to understand it. RLT is still newto most people, and the science behind it isn’t widely known outside biohacking and medical communities.
Most people still think red light therapy is just a gimmick, when in reality, it has decades of clinical research supporting its effectiveness for pain management, recovery, and even skin rejuvenation.
That’s why I launched the Lumaflex Academy and the Foundations Course—to package the science into a structured, easy-to-understand format that coaches, trainers, and therapists can use immediately.
By educating people first, we make sure that Lumaflex isn’t just another gadget—it’s a trusted, science-backed recovery tool.
Q: Red light therapy is gaining mainstream recognition, but there are still skeptics. What would you say to someone hesitant to try RLT?
A: Try it.
I was skeptical at first too. The science can sound complex, but at the end of the day, it’s not about words—it’s about results.
Millions of Americans rely on pain medication or consider surgery for issues that could be solved naturally. RLT is a proven, non-invasive alternative, but most people haven’t had the chance to experience it.
I always say: Give it two weeks of consistent use and see for yourself. That’s how I got hooked, and that’s how countless customers and athletes get hooked too.
Q: What sets Lumaflex apart from other red light therapy devices on the market today?
A: Lumaflex is built for real-world use.
Most RLT devices require you to sit still for 2030 minutes, making them inconvenient and hard to use consistently.
• Fully Flexible & Portable to joints, muscles, and even the face
• Direct Skin Contact – Maximizes treatment effectiveness
• Waterproof & Durable –Designed for military, first responders, and extreme envi ronments
• All-in-One Solution – Works for relief, performance, skin rejuvenation, and hair growth
THE BIGGEST CHALLENGE WASN’T CREATING THE TECHNOLOGY—IT WAS EDUCATING PEOPLE ON THE POWER OF RED LIGHT THERAPY.
John Graham Harper is a visionary entrepreneur, former competitive athlete, and the Founder & CEO of Lumaflex, a company revolutionizing red light therapy (RLT) for pain management, recovery, and performance. His journey into RLT began after suffering multiple sports injuries, including a brain tumor caused by head trauma from boxing. Introduced to red light therapy by his wife, he experienced firsthand its transformative benefits, leading him to create Lumaflex—the world’s first FDA-cleared, portable, flexible, and waterproof red light therapy device. Under John’s leadership, Lumaflex has become a global leader in RLT innovation, working with elite athletes, military programs, first responders, and wellness professionals. The company has been recognized with eight prestigious industry awards, including Time Magazine’s Best Invention of 2023, LifeSpan Certification, and Fast Company’s Innovation by Design Award. Lumaflex is also FDA-cleared for skin rejuvenation and hair growth, making it a multi-purpose solution for both beauty and pain relief.
Beyond products, John is committed to education and awareness, launching the Lumaflex Academy to equip trainers, therapists, and practitioners with the knowledge to integrate RLT into their protocols. In 2025, Lumaflex will expand its mission through the MAHA Alliance, further promoting natural healing solutions.
With a vision to change the world through light therapy, John continues to push the boundaries of health, wellness, and recovery technology, making RLT accessible and effective for all.
www.lumaflex.com
We aren’t just making another RLT device—we are creating a system that fits into people’s lives, ensuring consistent use for maximum results.
Q: The wellness industry is booming. Where do you see red light therapy fitting into the future of health and recovery?
A: I believe that in 3 years, every home will have 3 RLT devices.
Right now, beauty brands are driving awareness, and as more people experience it for skin rejuvenation, they’ll start using it for pain, longevity, and overall health.
RLT will soon become as common as drinking water, taking vitamins, or going to the gym. The key isn’t just awareness—it’s about which product integrates seamlessly into people’s lives. That’s where Lumaflex shines.
Q: In 2025, you are launching the MAHA Alliance. Can you share more about its mission and impact?
A: The MAHA Alliance is about making America healthy again.
Meeting RFK Jr. and his team was inspiring, and we are proud to be part of this movement. The healthcare system is broken, and people need better, more natural solutions for recovery and pain management.
Lumaflex will play a major role in bringing RLT to the forefront of this wellness revolution.
Q: If you had to sum up Lumaflex’s mis sion in one sentence, what would it be?
A: "To heal the world of pain with light."
We’re not just sell ing a product— we’re leading a movement toward natural, effective recovery solutions that put people back in control of their health.
This is bigger than busi ness—it’s a revolution.
Our mission is simple - to help everyone on Earth move better, live better and be better.
Whether you’re an elite athlete or an individual who is simply looking for solutions to combat the impact of daily life, our suite of innovative products are here to help you unlock the best version of yourself. So you can always be at the top of your game, no matter what that game might be.
1r Agency is a leading force in the digital realm, collaborating with a diverse range of start-ups and established brands in the Fashion, Beauty, Skincare, CPG, Home & Retail Development and Health & Wellness sectors to bolster their direct-to-consumer (DTC) presence. 1r creates unique experiences that blend best-in-class e-commerce features and functionality with beautiful, tactile designs to tell rich brand stories. The agency's main pillars are creative, digital, and marketing, with service offerings spanning content strategy, creative direction, website design, website development and Integrations, business analysis and solutions, UX and strategy, paid social, paid search, email/SMS marketing, SEO.
What inspired you to launch one of the first e-commerce agencies? What gap did you see in the market that 1r could fill?
In 2006, when I was the Creative Direc-
tor of Accessories at Theory, I developed a keen interest in eCommerce and its impact on the future of retail. At that time, only a few established fashion brands like Tory Burch, Ralph Lauren, and DVF were venturing into eCommerce, while many small to medium-sized brands were hesitant to take the leap. Major names like Jimmy Choo and Burberry were starting to launch DTC, but others, like Theory, Rag & Bone, and Marc Jacobs, were still not online. Overall Fashion brands were slower to adopt eCommerce compared to other industries. They remained heavily reliant on traditional retail stores and expensive print advertising, often due to concerns over maintaining brand prestige and the tactile, exclusive shopping experience associated with in-person retail.
While big agencies like Razorfish catered to larger brands, there was a clear gap for agencies that understood fashion and could support small and mid-sized brands. 15 years ago, when we started the agency, it was the beginning of the eCommerce era. Fashion brands needed to shift their mindset—from viewing eCommerce as an “unwanted guest” in their ecosystem to recognizing it as crucial for establishing a brand presence and engaging with customers.
From day one, 1r aimed to elevate online brand experiences, showing brands that DTC could be a creative extension of their identity, a powerful marketing tool, and a strong revenue driver. The brands that thrived early on recognized the importance of owning their customer relationships and moving away from reliance on department stores. My firsthand experience on the business side of fashion gave me a deep understanding of the symbiotic relationship between fashion, design, and business.
Our approach wasn't just about design and tech; we were business consultants, helping clients integrate eCommerce into their broader operations. It was about creating self-sufficient ecosystems and navigating the financial and logistical challenges of going online.
From the start, we were lucky to partner
with some incredible brands like Mara Hoffman, James Perse, and Sam Edelman, who embraced this new era and flourished.
Your Agency Has Worked With Some Iconic Brands And Celebrities. Can You Share Some Notable Clients And How Your Approach Differs When Working With High-Profile Clients?
The stakes are high for celebrity clients, but they’re equally high for any business we work with. Our goal is always to provide white-glove service, regardless of the client. Our approach doesn’t change based on the celebrity status of a client; we consistently strive to create a unique brand experience and deliver the highest level of service.
There are certainly nuances when working with celebrities. Their high profile often requires a more flexible and adaptive approach to project management and timelines. The main difference is the need for infinite flexibility in delivering solutions. Time constraints and the demands on celebrity clients mean that we must seize opportunities to connect with them whenever they arise, even if it’s outside of our normal process.
Being prepared for any in-person interaction is crucial. We need to think ahead about the decisions that need to be made and present options without restricting choices until the last possible moment. Celebrity teams are usually juggling multiple projects, initiatives, and social activities, so it’s essential to bring all our teams—business, product development, social, design, and operations—to the table to help launch the project.
Celebrity-led launches often attract high traffic due to their exposure, so it’s critical to coordinate with PR teams and all third parties to ensure everyone is in sync. Perhaps celebrities come to 1r Agency because they trust us. Over the years, we’ve had the privilege of working with iconic brands and celebrities like WYN Beauty by Serena Williams, Joopiter by Pharrell Williams, and Westman Atelier with Gucci Westman, a makeup artist to top Hollywood stars.
Since starting 1r in 2010, I've witnessed the online retail industry evolve at an incredible pace. One of the most significant shifts has been the lowered barriers to entry for brands looking to establish an online presence. Today, it’s easier than ever to get a brand online, with minimal investment required to produce and operate an eCommerce store. This shift allows brands to focus more on product development, R&D, PR, and marketing.
However, with opportunity comes increased competition. The multitude of channels available for selling and marketing continues to expand rapidly, making it crucial for brands to differentiate themselves. The key questions now are: How do you stand out? How do you stay authentic? What is your unique value proposition? Brands must be clear on which channels work best for them and which convert most effectively. The pro-
cess of getting consumers to complete a purchase has become more complex, and it’s crucial for brands to approach this as a learning journey. Adopting an agile mindset, leveraging data, and constantly refining your voice are essential strategies.
When we first started, established brands often viewed eCommerce as a necessary but secondary channel—something to layer on top of their existing business processes. Many saw e-commerce as a catchall solution for their business problems, whether it was inventory issues or pricing challenges. But over time, eCommerce and digital channels have become the backbone of a brand’s business.
'Staying ahead of the curve when it comes to technology is essential, but it shouldn’t come at the expense of a brand’s health and growth. While we strive to be innovative and at the forefront of online experiences, we don’t push our clients to be early adopters just for the sake of it. We focus on future-proofing our clients and ensuring they benefit from the latest advancements without becoming guinea pigs for untested technologies.
1R WAS A GREAT PARTNER FOR US TO REDESIGN AND REPLATFORM OUR SITE. THERE WERE A LOT OF COMPLEXITIES MOVING FROM A CUSTOM PLATFORM AND CUSTOMIZABLE PRODUCT WITH SUBSCRIPTIONS. 1R STRIKES A GOOD BALANCE IN DELIVERING BOTH CREATIVE AND TECHNICAL SOLUTIONS TO MAKE OUR PROJECT SUCCESSFUL.
Ross Miller
In the early days, meetings with brands often involved their CEO, buyer, or head of retail alongside someone from the technology department. Now, the digital team or CMO plays a central role in defining the business strategy. This shift underscores how integral eCommerce has become to a brand's overall success.
Our role is to stay ahead of the latest trends and technologies, but it’s not a one-size-fits-all approach. We leverage our community of clients to understand what works best for specific brands and verticals. Our job is to inform our clients about what’s available, while also ensuring they remain true to their brand identity.
Our strategy involves holistic optimization across all aspects of eCommerce, including social media, email marketing, SEO, logistics, and user experience. We prioritize seamless integration and the effective use of the platforms we work with, ensuring our clients maximize their capabilities.
Innovation is often internal for us, focusing on building and integrating services that extend our clients’ budgets and timelines. For example, when we first started building on Shopify Plus, there wasn’t a recognized enterprise-level approach to source control, CI/CD, or deploying Shopify Plus solutions. We developed an enterprise approach to ensure our clients could scale without barriers, pushing the boundaries of automation and optimization.
Ultimately, our focus is on creating a frictionless experience between digital and in-store interactions. Anything that mimics a high-touch, personalized experience is paramount to the consumer journey. Personalization must feel natural, and not overly intrusive. It’s important to find the balance between personalization and privacy.
Acquisition and retention succeeds when a brand knows who they are at their core and delivers on that promise consistently. These are fast-changing times, and technology is advancing at lightning speed, but creating cultural capital through a brand’s story and values remains essential. This means meeting consumers where they are, both online and offline, and delivering a human connection that aligns with their expectations.
While the term “omni-channel” is often used, I prefer to say that it’s about meeting your consumer where they are, providing a seamless and engaging experience across all touch points.
Can you walk us through your creative process when taking on a new project? How do you ensure that the development of materials and ideas are both on-brand and on-target?
Our creative process is rooted in deeply understanding our client’s vertical and business, with the goal of elevating their brand aesthetic while staying true to their unique identity. We start with a comprehensive discovery period where we bring together cross-functional teams— creative, technical, business, product, and solutions—to research the brand, competitors, and market opportunities. Our approach is holistic, informed by data and stats to ensure we design with the end-user in mind.
rience in designing for the web or the specific platform being used. This can lead to disconnects between design and development, longer timelines, and inefficiencies. At 1r, our creative teams work closely with technical teams to ensure a streamlined approach that aligns with our clients’ KPIs and platform capabilities. During our discovery phase, we produce two creative outputs— one conservative and the other more boundary-pushing. This helps ensure alignment with the client’s visual direction before diving into detailed designs. We focus on understanding the brand’s history, vision, and future trajectory to create an experience that is not just for launch day but for long-term growth.
1r’s DNA is very brand-centric. I think everything we do starts from that creative lens. This is evident even from the proposal phase, where we tailor our approach to each prospect. Our QA process is rigorous, ensuring no creative drop-off between the initial deep dive and the final launch. We take a highly curated approach, considering a brand’s future roadmap and ensuring seamless integration with all other channels.
1R HAS CREATED AN EXCEPTIONALLY IMPACTFUL AND MODERN DIGITAL EXPERIENCE FOR DIBS BEAUTY. THEIR EXPERTISE IN DESIGN, E-COMMERCE STRATEGY, AND WEB DEVELOPMENT, COUPLED WITH THEIR HANDS-ON COLLABORATION WITH OUR TEAM, HAS LED TO TREMENDOUS GROWTH AND OPPORTUNITIES FOR OUR BRAND.
Mindy Luong
What role do sales, merchandising, brand extension, marketing, and public relations play in your approach to guiding clients?
integrated as part of the broader business ecosystem.
We need to have knowledge across all touch points—brand story, customers, wholesale, retail, etc.—to advise appropriately. eCommerce is not just a consumer-facing project; it’s also a business-facing one. We approach it with the same weight and attention as we do the front-end, consumer-facing elements.
We see ourselves as conductors in the eCommerce ecosystem, ensuring that all partners, players, and stakeholders are aligned. Brands that embrace a comprehensive, integrated strategy across all channels are the most successful. Isolating any channel will not work. At 1r, we believe creativity powers commerce, and our success lies in understanding what our clients need and how to get them there.
What are the top Services Major Brands and Celebrities Seek from Your Agency?
At the end of the day, clients come and stay with us for all sorts of reasons. Our relationships with them ebb and flow as their business needs change. There’s no one-size-fits-all approach because every brand requires a different strategy.
We started out primarily as a web design and development agency, but we quickly saw the need to expand our services to cover the entire spectrum of digital eCommerce. When content became a central focus in the industry, we added a deeper creative offering to support content strategy across all digital channels. We noticed that many brands weren't optimizing the content they were creating, or using it in a way that truly worked for them, and we wanted to change that.
A common mistake brands make is working with designers who lack expe-
As an agency, we take a 360-degree view of our clients’ businesses, encompassing all aspects of marketing, sales, and public relations. Every element is crucial for success, and each aspect feeds off the other. Our job is to navigate the best way to allocate our clients' budgets and resources, ensuring that eCommerce is
For years, we had been dreaming of bringing digital marketing into the fold, to be more involved in the growth of our clients' businesses. About three years ago, we launched our growth services, which include paid media, organic social, and email/SMS marketing. The goal was to maximize the impact of our clients’ budgets and drive measurable business results.
PHOTOGRAPHER
YESI @YESI.
MODEL SHELLY SOCOL
@SHELLY SOCOL
AGENCY 1R AGENCY
@1R.AGENCY
FASHION STYLIST
ANTHONY BERMUDEZ
@IAMANTHONYBERMUDEZ
HAIR AND MAKEUP ARTIST
MONICA GAVIRIA
@MONICA GAVIRIA
@MIAMIBRIDALANDBEAUTY
VIDEOGRAPER DAVID ARAUJO
@DAVIDARAUJO.TV
@LAFILMINC
CREATIVE DIRECTOR
IRYNA VOSKERICIAN
@IRYNAVOSKERICIAN
ARTIST ANTONIA KUO WARDROBE
PHOTOGRAPHER
YESI @YESI.
MODEL SHELLY SOCOL
@SHELLY SOCOL
AGENCY 1R AGENCY
@1R.AGENCY
FASHION STYLIST
ANTHONY BERMUDEZ
@IAMANTHONYBERMUDEZ
HAIR AND MAKEUP ARTIST
MONICA GAVIRIA
@MONICA GAVIRIA
@MIAMIBRIDALANDBEAUTY
VIDEOGRAPER DAVID ARAUJO
@DAVIDARAUJO.TV
@LAFILMINC
CREATIVE DIRECTOR
IRYNA VOSKERICIAN
@IRYNAVOSKERICIAN
ARTIST ANTONIA KUO
Introducing growth services was a significant move for us, helping us transition from being just a digital partner to becoming a true business partner. Our philosophy is straightforward: "if they grow, we grow." This shift has allowed us to form deeper, more meaningful partnerships with our clients.
We understand you have a passion for art. How does this passion influence your work in the fashion and e-commerce industry?
Art, design, creativity, style, and fashion are the core of who I am. I studied fine arts in Israel at Bezalel Academy of Art and Design and later at Cooper Union in NYC. I’ve always had a deep passion for creating and collecting art, and this passion is one of the pillars of 1r Agency. It’s the foundation upon which the agency was built, and it helps attract fellow creatives and art and design enthusiasts.
creative vision and approach to brand development?
My mother, Sharon Socol, an art photographer and collector who sits on the board of photography for The Whitney ignited my passion for art early. I’ve been an avid collector of emerging artists over the years, starting in my early 20s after attending Bezalel Academy of Art and Design in Jerusalem where I studied fine arts with a focus on performance art, drawing, sculpture, and photography.
CHOOSING 1R FOR DESIGN AND THE BUILDING OF OUR SITE WAS A REALLY GREAT DECISION THAT COULDN'T HAVE WORKED OUT MUCH BETTER. THEY DELIVERED A BEAUTIFUL AND MODERN SITE WITH FUNCTIONALITY THAT WILL REALLY HELP US TAKE OUR BRAND TO THE NEXT LEVEL IN THE YEARS TO COME.
Adam Ellicott
My work at the agency seamlessly blends my passion for art, love for design and brands, and enthusiasm for pushing the boundaries of storytelling, whether through visual art or digital platforms. At its core, it's about conveying emotion and creating a lasting impact on the viewer. My work in the digital space has inspired the pieces I've collected over the years.
We leverage our strong client relationships to share experiences when possible, always being mindful of what can and cannot be shared. Our clients’ trust is paramount.
Luckily for us, we have a lot of really great relationships with our clients. We do our best to leverage those who are more willing to allow us to share our experiences. For example,
“1R was a great partner for us to redesign and re-platform our site. There were a lot of complexities moving from a custom platform and customizable product with subscriptions.
1R strikes a good balance in delivering both creative and technical solutions to make our project successful.” Ross Miller, SVP of Digital for Function of Beauty
“Through the years, 1r Agency has been our digital backbone, crafting and maintaining our website. The client services team's dedication is unparalleled—a true partnership of trust and success. I couldn't imagine our journey without them.” Katelyn Lorry, Associate Director, Digital Engagement, Seaport
My affinity for beautiful things and innate respect for how they are created drive everything we do at 1r. I am constantly thinking about how our brand is perceived externally. I believe that when our prospects or existing clients see how seriously we take our brand’s appearance, it promotes trust in how we approach our work. They know we care as much about our own brand as we do about theirs. I am always evolving, reiterating, and driving how we, as a brand, present ourselves at every touchpoint, never staying stagnant. I am the primary motivator of this, and I feel our team and our clients recognize and appreciate it.
Are there any particular art movements or artists that inspire your
My collection includes pieces from artists like The Starn Brothers, Sara Cwynar, Antonia Kuo, Ben Tong, Rafaël Rozendaal, Elliot & Erick Jimenez, & Louise Bourgeois, just to name a few. Recently I collaborated with Maria Vogel, an Art Advisor, hosting a dinner party during Frieze NYC, for young artists and collectors at our family's SOHO loft.
As a media resource for outlets like Bloomberg and Business of Fashion, how do you balance providing insights to the media while maintaining confidentiality for your clients?
When interviewed by outlets like BOF, Vogue, Bloomberg, and Glossy, I’m often asked to weigh in on new trends, brand launches, and the overall state of DTC.
“1R has created an exceptionally impactful and modern digital experience for DIBS Beauty. Their expertise in design, e-commerce strategy, and web development, coupled with their hands-on collaboration with our team, has led to tremendous growth and opportunities for our brand.” Mindy Luong, Vice President of Digital for DIBS Beauty
What’s most powerful is my ability to share insights from our vast experience across diverse clients, brands, and verticals. When speaking to the press, I synthesize learnings from all our clients, providing valuable insights without focusing on individual brands. I emphasize overarching trends while integrating unique interpretations, helping brands remain competitive while staying true to their identity and goals.
What are some key messages or trends you emphasize when speaking to the press about the future of e-commerce and fashion?
While it’s crucial to stay competitive and up-todate with the latest industry trends, I always stress the importance of brands aligning their key messages and digital investments with their core identity. Brands need to look within to ensure they’re staying true to who they are today and where they see themselves going in the next year, 5 years, or even 10 years.
I encourage brands to plan not just for the immediate future but to think longterm. This includes considering how their digital strategies and brand messages will evolve over time. It’s about being adaptable and forward-thinking while staying grounded in the brand’s core values.
As a subject matter expert, I’ve had the opportunity to provide insights on significant market movements. For example, I’ve commented on Coty’s investment in SKKN by Kim Kardashian, discussed
strategies for balancing growth and retention, and advised emerging beauty brands on how to avoid pitfalls during rapid expansion.
These are the messages I focus on when speaking to the press, reflecting my approach to understanding and navigating the complex, fast-paced world of eCommerce and fashion.
Looking ahead, what do you believe are the next major trends or innovations that will shape the future of e-commerce and online retail?
The future of eCommerce lies in interconnectedness, rapid production, and the adoption of SaaS-based platforms. AI, particularly generative AI, will significantly impact search and marketing. In fashion, I anticipate a shift towards more authenticity, the end of fast fashion, and a focus on personalized brands with strong
customer relationships. Sustainability is also critical, with an emphasis on understanding the entire product lifecycle.
We haven’t scratched the surface of AI’s potential. Tools that generate bulk meta and alt tags or optimize email campaigns are just the beginning. AI will factor into various tools, from email service providers like Klaviyo to platforms like Shopify, helping brands create workflows and content more efficiently. Additionally, sustainable returns will evolve, with brands increasingly reselling lightly used products instead of sending them back to warehouses. Personalization, virtual technology, and data are crucial. Brands must tailor content and products to individual consumers based on browsing history and preferences. Understanding consumer engagement is essential, and brands must contin-
uously iterate to meet consumers where they are.
How is 1R preparing to adapt to these upcoming changes and continue to provide value to your clients?
We prepare our team to embrace AI, driving efficiency and guiding clients on its use. eCommerce requires a collaborative approach, involving multiple disciplines and teams. At 1r, we are adapting, learning, and embracing AI as a tool for productivity and innovation. We want to be early adopters, not just for personal or professional gain, but to help our clients and brands stay ahead of the curve.
Our team is dedicated to learning as much as possible to maintain our position as an authority in e-commerce and technology. That’s the value we bring to our clients—staying informed, being flexible, and guiding them through the ever-changing digital landscape.
What advice would you give to aspiring entrepreneurs looking to start their own agency or enter the e-commerce space?
The agency space is highly competitive, so having a clearly defined value proposition and a strong differentiator is crucial. Ask yourself, “Is there room for more agencies?” If you’re entering this market, you need to offer something specialized and personalized. Your value proposition must be well-defined, and you should be creating something that doesn’t exist yet.
Starting an agency requires a roadmap, strategy, and operational guardrails. It’s essential to approach your business from multiple angles and be flexible enough to evolve. Every year, we at 1r set our strategic plan with a focus on what’s next. Even if we’re doing something well, we’re always looking for ways to improve. Sometimes it’s about making small, considered changes, but the key is to always be willing to evolve.
How important is it to have a multidisciplinary approach, combining
elements of creative design, marketing, and technology, in today’s e-commerce landscape?
Creative design, marketing, and technology are deeply interconnected in today’s eCommerce landscape. While it’s essential for brands to tailor their messages and content for each digital platform— whether it’s a website, social media, or email—the overarching themes, tone of voice, and messaging must remain consistent across all channels. Building a strong relationship with the consumer is key.
To be truly successful, you can't lean too heavily on one aspect over the others. For instance, creating a visually stunning experience is important, but if users struggle to find the shopping cart or complete the checkout process, you’re not meeting their needs with best practices.
eCommerce touches on many facets— technology, content, product, storytelling, marketing, and customer service. At 1r, we recognize the importance of a multidisciplinary approach, ensuring we engage with all the relevant teams and practices involved in an eCommerce business. Our approach is entirely collaborative, reflecting the interconnected nature of the industry.
What has been the most rewarding project you’ve worked on at 1r, and why?
There are so many rewarding projects, each bringing growth and learning. However, a few stand out for various reasons. Joopiter, Pharrell Williams’s art auction site, was a particularly intriguing project due to its high-profile, global reach and inherent complexity.
While we were confident in our team's ability to deliver, working on an art auction site with instant online bidding was outside our typical scope. However, this project truly demonstrated our team's ability to collaborate, innovate, and execute on a global stage. We were integral in creating the entire product, incor-
porating cutting-edge technologies and ensuring its success on such a visible platform.
Vera Bradley was undoubtedly one of the largest and most complex projects our team has ever undertaken. Our role as the lead conductor involved coordinating not only with the client but also with 18 other third parties that needed to be integrated into the system. Delivering a solution for a brand of that stature—with over 160 brick-and-mortar stores and a significant multi-million-dollar online business—showcases the technical expertise and professionalism of 1r. Our ingenuity in managing such a massive project proves that we can deliver on a grand scale, regardless of the challenges. Notably, this was the largest Shopify Plus implementation at that time in 2020 Personally, I have a few favorites, such as Westman Atelier, where we’ve been involved from day one, watching their exponential growth into one of the most important beauty brands on the market. DIBS Beauty is another favorite, where their clear value proposition and calculated business growth have been impressive.
WYN Beauty by Serena Williams is also a project that I am very proud of. It has been an honor to work with such a legend on the eCommerce portion of her beauty brand. The brand celebrates showing up as the best version of yourself and being the premier destination for color beauty. It was exciting to work hand in hand with their team in devising strategic solutions that facilitated the presentation of various product shades across different sections of the site while ensuring top-tier performance and accommodating dynamic content.
Most rewarding for me, however, is seeing our long-standing partnerships with clients like Carhartt Work In Progress, White + Warren, Norma Kamali, Boston Seaport, COTY, Havaianas, WS Development, and many others. This is a testament to our team’s dedication, especially our client service team, who truly see the brands they manage as their own.
HAS SCULPTED SKINLOCAL INTO A SKINCARE PHENOMENON, WHERE PASSION MEETS INNOVATION, AND BEAUTY MEETS PURPOSE. THEIR MASTERY OF SEO, CREATIVE EXPERTISE, AND DEVELOPMENTAL INSIGHTS HAVE NOT ONLY FUELED GROWTH BUT HAVE ALSO SET A NEW STANDARD FOR EXCELLENCE IN THE INDUSTRY.
Julia Campos
Can you share a defining moment in your career that significantly impacted your professional journey?
I’ve had a rather unique career journey that’s shaped who I am today. Before founding 1r, I had some incredible experiences that taught me a lot about resilience and building from the ground up. Back in 1992, I worked for the National Organization for Women, supporting women running for political offices across California. It was empowering to be part of something so meaningful at a time when women’s voices were just starting to gain more traction in politics. After that, I took on the role of Executive Director of the Elie Wiesel Foundation in Israel, where I established educational centers for Ethiopian immigrant children and their families. This was a profound experience—creating something from nothing, helping to build a future for those kids and their families.
When I returned to the States, I entered the fashion world at Theory as the Creative Director of Accessories. It was an exciting time, and again, I found myself building from scratch, pushing boundaries, and creating something entirely new. But honestly, nothing compares to the challenge and fulfillment I’ve found in owning, building, and creating my Agency, 1r. This journey has been deep-
ly personal and rewarding on so many levels. It’s not just about the success we’ve had as a company—it’s about the impact we’ve had on the lives of our employees. I’ve been incredibly fortunate to have people stay with us for years, grow their careers, get married, have families, and build their lives alongside us. Our success is truly a reflection of them.
One of the most defining moments for me was during COVID. Like many companies, we had to downsize, and letting people go was incredibly painful. During that time, over communication became our lifeline. The executive team and I made ourselves constantly available, increasing the frequency of town halls to bi-weekly, sometimes even daily. It was a difficult period, but it taught us the importance of leaning into those sharp edges and being there for each other.
Getting through COVID and the years that followed was a pivotal moment in my career. I learned so much about myself as a leader—about the importance of transparency, consistency, and empathy. Every decision we made had a direct impact on our team and their families, and I felt the weight of that responsibility deeply. COVID tested us, but it also brought us closer and crystallized how strong and resilient our team is.
How do you balance the demands of motherhood with running a successful agency? What advice would you give other working moms? Has being a mom changed your perspective on your career and goals? If so, how? What values do you hope to instill in your children through your work?
Finding that life/work balance is something I’m constantly working on—especially since running my own business is like raising another child. When I started my agency, my two kids were very young, so it was incredibly challenging.
I didn’t take a vacation for years and put everything financially into building the company. Over time, I learned just how vital it is to allow myself downtime to rest and pursue other passions. Surprisingly, it wasn’t just the rest that helped me; it was exploring those other interests that actually boosted my energy and inspired the direction of the company.
Being a mom has completely reshaped how I approach work and life. It’s forced me to become more focused and diligent with my time. Many of the parents who work for me are among the most productive people I know, which makes sense—we know how to make every moment count.
Balancing travel and work with being an emotionally and physically present parent was a challenge, but I made it a priority to shut down at 6 pm and focus solely on my kids. Family dinners are non-negotiable. While my children have definitely felt my absence at times, they’ve also learned a lot from watching me build something from the ground up. It’s pretty funny, actually—my son can perfectly imitate how I pitch to new clients, right down to how I introduce myself and the agency. So, I guess it’s made an impact.
How would you describe your management style? How has it evolved over time? What are the key qualities you look for when building and leading your team? How do you foster a culture of creativity and innovation within your agency?
My management style has always been My management style has always been about hiring people who are smarter than me and then clearing the blockers for them. I’m not a micromanager at all. I have so much respect for the expertise my team brings, and I support them fully. I’ve been incredibly fortunate to have an executive team that’s been with me for over 12 years, and many of my managers and directors have been at 1r for nearly a decade. It’s a true testament to the culture we’ve built together.
For me, professional growth is non-ne-
gotiable. 1r is a smaller agency, which gives people a chance to flex their skills and really grow. I’ve seen employees come in at entry-level roles and rise to Director and even C-level positions. Creating a space where people can grow within the organization and not feel stagnant benefits both the employee and 1r.
I also encourage exploration—per sonally and professionally. We’ve had team members leave for other oppor tunities and then return to 1r. My door is always open. I never want to hold anyone back from exploring what’s out there.
cisions when building and running your agency?
Education and exposure are also key. There hasn’t been a single year where professional growth wasn’t a top priority for the agency. We always aim to expand our team’s knowledge and skills, which ultimately drives 1r forward.
From day one, we’ve shared the agency’s annual strategic goals with the entire team, so they always have the big picture in mind and understand how they play a role in achieving it. When day-to-day work gets tough, this framework helps everyone stay grounded.
What core principles guide your de-
A guiding principle for me is that everyone on our team is inherently creative. At 1r, creativity isn't just a buzzword—our motto, "Creativity Powers Commerce," is something we truly live by. I firmly believe that creativity isn’t confined to our designers; it’s something everyone, whether in finance, development, project management, or any other role, should tap into. I constantly challenge our team to think outside the box, to find innovative solutions not just for our clients, but for themselves and the agency as a whole. Creative thinking is the heartbeat of 1r.
Another principle I hold dear is the importance of constant evolution, both personally and professionally. Evolution doesn’t need to be rapid; it can be slow, thoughtful, and deliberate. I’m very conscious of the many mistakes I’ve made over my 15-year journey, but I see those mistakes as opportunities to recalibrate rather than as failures. I encourage everyone on our team to stay agile, remain open, and to adjust their course when necessary.
Finally, I can't stress enough the power of teamwork at 1r. I’m incredibly fortunate to be surrounded by such a collaborative and dedicated group of people. Our team excels in this area—everyone is always willing to come together, roll up their sleeves, and do whatever it takes to achieve our goals. It’s that collective spirit that truly sets us apart.
How has networking influenced your career, and how do you continue to innovate and grow?
In recent years, I’ve made it a point to focus on in-person networking, particularly within the beauty industry. I’ve attended some of the most incredible conferences across the states, and it’s been transformative for me as a professional, a CEO, and as a woman. I’ve met some of the most innovative and inspiring people, forging deep and meaningful connections. It’s reignited my passion and given me new insights to bring back to 1r. For me, continued education is crucial. I’m insatiable when it comes to learning new things, exploring different disciplines, and pushing my thinking further. Innovation isn’t just about technology— it’s about evolving yourself, your mind, and your approach. We all have the ability to change; it’s just about making the decision to leap into uncharted territory and see where it takes you.
Dr. Nathan Newman is a world-renowned dermatologist, cosmetic surgeon, and pioneering expert in stem cell therapy, based in Beverly Hills. Over 25 years ago, he discovered a groundbreaking method to harness the transformative power of stem cells to rejuvenate and enhance facial aesthetics, which set him on a lifelong mission to advance stem cell science for wellness and healing. His journey began with the creation of the Stem Cell Lift®, a proprietary, minimally invasive technique that uses patients' own autologous stem cells to promote natural healing, transformation, and wellness.
Dr. Newman's innovations continued beyond aesthetics. Inspired by the remarkable outcomes of his procedures, he expanded his stem cell applications, utilizing them in clinical and surgical settings to improve skin post-surgery, aid in post-cancer reconstructions, and address autoimmune-related skin disorders. Driven by the potential of plant-based stem cells, he established a cutting-edge Research and Development facility, which led to a revolutionary breakthrough: STEM, a consortia factors platform that integrates the innate "language" of stem cells to naturally work with the body rather than on it. This patented, original technology represents a paradigm shift in holistic
wellness, offering an innovative, vegan, and sustainable "cell-to-bottle" approach accessible to all.
Dr. Newman’s education and training reflect his dedication to excellence. He began his academic journey at the University of Southern California (USC), earned his medical degree from the Albert Einstein College of Medicine in New York, and completed his internship in internal medicine at UCLA-VA Medical Center in Los Angeles. His dermatology residency took place at Cook County Hospital in Chicago, followed by a fellowship through the American Academy of Cosmetic Surgery in Riverside, California. Board-certified in Dermatology, Dr. Newman is recognized internationally for his expertise in cosmetic surgery and regenerative medicine.
Dr. Newman is a leading authority on stem cell applications and has been published extensively in prestigious medical journals. He is a sought-after international speaker, frequently interviewed by media worldwide, and honored by the America’s Registry of Outstanding Professionals and Cambridge Who’s Who for his contributions as a pioneer in stem cell biotechnology. Holder of four patents in medical devices and biotechnology, his latest achievements include the patented platform consortia factors technology, a landmark advancement in wellness science.
Dr. Brei’s doctoral studies at the prestigious University of Toronto’s Chemical Engineering and Applied Chemistry department encompassed both water and microbiome research. With this robust research insight and deep perspective into the microbial world, Dr. Brei established a uniquely powerful foundation for her skin care research. Today, Dr. Brei lives in Toronto Canada with her husband and two children. NuVsio Minerals Support a Healthy Skin Microbiome by providing a ‘Second Skin’ protective layer against Environmental stressors, toxins and pollution.
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