Autumn 2015
Putney Academic Focus
Putney Old Girl and parent Professor Mala Maini studied medicine at Guy’s Hospital, and specialised in infectious diseases and HIV. After completing her specialist accreditation, she decided to side-step out of full-time medicine and try her hand as a research scientist; funded by a Medical Research Council Clinical Training Fellowship, she gained a PhD in Immunology in 1998. After becoming hooked on the thrill of experimental research, she combined work as a Consultant Physician with building up a research group investigating the immune mechanisms underlying the infectious diseases from which her patients suffered. After studying glandular fever and HIV, her research team has concentrated for the last 15 years on the hepatitis B virus, which still kills more than 600,000 people a year. Their work is internationally recognised for its contribution to this rapidly developing area of scientific research. Mala was promoted to Professor of Viral Immunology in the Division of Infection and Immunity at UCL in 2009 and awarded a Wellcome Trust Senior Investigator Award in 2013.
“Working as a doctor or a research scientist is a vocation not a job; most people I know are so passionate about what they do, they’re almost surprised they can be paid to do it! So don’t be put off by the competition and hard work, it will all be worth it to do something you’re really excited by, and make a difference to other people’s lives in the process.”
Medicine, Dentistry & Veterinary edition M
ALA SAYS: A medical degree opens the door to so many different career paths, there is something to suit every personality – and you can even try several of these paths in one career, like I have.
I’ve volunteered on a project in Zambia, helping to run a clinic for patients with AIDS and tuberculosis and taking time out to camp in the bush protected by nothing more than a mosquito net. I’ve specialised in HIV Medicine and spent years getting immensely involved in a large caseload of patients dying from AIDS in the years before successful antiviral treatment.
Then for the past 20 years I’ve moved into medical research, obtaining a PhD in viral immunology, and running a laboratory aiming to develop new immunotherapies for hepatitis. I still see patients, which never ceases to feel like an immense privilege for the trust people place in you and the chance to touch their lives in often just small ways. But now I also have the intellectual stimulation of researching a very dynamic field, and the thrill of: planning experiments and seeing new data emerge; scouring literature for clues to support our findings; discussing ideas with brilliant colleagues; travelling the world to present our findings and hear about the latest developments; training the next generation of scientists and clinical researchers; and heading a team that is hopefully contributing towards the groundwork that will inform the development of new treatments for millions of patients in the future.
The hepatitis B virus infects the liver and kills more than 600,000 people a year.
I think I would have felt daunted if I’d read about these experiences when I was still at Putney – I don’t think I would have imagined myself capable of any of this in a million years. It is hard to believe how many doors will open for you with a bit of serendipity and a lot of determination and enthusiasm. You don’t have to have it all mapped out from the beginning, just stay flexible and open to new opportunities and when you find a job you’re really passionate about, it won’t even feel like work.
I’ve worked as a hands-on junior doctor, learning a huge amount of general medicine in a district general hospital in Devon, rushing to cardiac arrest calls at 3am, enjoying the camaraderie of being part of a busy team and living in the sociable ‘Doctors’ Village’. I’ve trained at the Hospital for Tropical Diseases in London, checking travellers for a variety of horrible worm infestations and looking at blood samples sent from hospitals round the UK for malaria parasites in the middle of the night.