2019 Swanson School Summary of Faculty Research

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BIOENGINEERING 302 Benedum Hall | 3700 O’Hara Street | Pittsburgh, PA 15261

George Stetten, MD, PhD Professor

P: 412-624-7762 stetten@pitt.edu

Primary Research Areas The Visualization and Image Analysis (VIA) Laboratory, directed by George Stetten, MD, PhD, is developing new methods of displaying and analyzing images, primarily for medical applications. We have introduced a new device called the Sonic Flashlight® for guiding invasive medical procedures by placing ultrasound images directly within the patient (see top figure below), so that the clinician can see the internal anatomy in-situ, visually fused with the external anatomy and the surgical tool. After extensive development and successful testing in patients for the placement of catheters in the deep veins

of the arm, we are currently looking for partners to commercialize the technology based on issued US and foreign patents to the University of Pittsburgh. With more than a decade of continuous funding from the NIH, we have extended the approach to holography-based displays and are currently developing a similar in-situ image guidance system to display optical coherence tomography under the surgical microscope to guide eye surgery. We are also developing a system called ProbeSight, using video cameras mounted on the ultrasound transducer to the incorporate visual information from the

surface of the patient with the ultrasound data for better anatomical localization. Most recently, we are developing a new type of surgical tool, the Hand-Held Force Magnifier, which provides a magnified sense of force at the tip of the tool for microsurgery (lower figure), by actively pushing or pulling on the handle of the tool relative to a brace attached to the back of the hand. Other projects include FingerSight TM to allow visually impaired individuals to sense the visual world with their fingertip, as well as automated image analysis systems for 2D and 3D medical images.

Further Research and Background George Stetten earned an A.B. in Engineering and Applied Physics from Harvard in 1976, an M.S. in Biology from NYU in 1986, an MD from the SUNY Syracuse in 1991, and a PhD in Biomedical Engineering from UNC, Chapel Hill in 1999. Dr. Stetten wrote the software for the first computer system onboard Deep Submersible Alvin at the Woods Hole Oceanographic Institute and designed a telemetric egg to study incubation of endangered birds at the Bronx Zoo that was nominated for the 1992 Discover Magazine Award for Technological Innovation. He conducted the first full-scale classroom in which laptop computers were networked wirelessly in 1994, helped develop the first Real-Time 3D ultrasound scanner, and was a founding contributor to the National Library of Medicine Insight Toolkit for image analysis (ITK). He received the 2004 Chancellor’s Distinguished Research Award in the Junior Scholar category from the University of Pittsburgh and is a fellow of the American Institute for Medical and Biological Engineering. Dr. Stetten is currently Professor in Bioengineering at the University of Pittsburgh and a Research Professor at the Robotics Institute at CMU, with courtesy appointments in Radiology at the University of Pittsburgh and Biomedical Engineering at CMU. He served as Co-Director of the CMU/Pitt Medical Scientist Training Program from 2007-2011. He is the founding director of the new Music Engineering Laboratory (MEL) in the School of Engineering.

DEPARTMENT OF BIOENGINEERING

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