PiloKit® & PiloSpray® World's 1st Piles & Fissure Spray Treatment

Clinically proven plant-based medicines

HEALING HANDS

Medicines For Anorectal Diseases

PiloKit - PiloSpray, PiloTab & ConstiTab Combination Treatment for Hemorrhoids & Fissure

Healing Hands & Herbs Pvt. Ltd.

101, Mangalmurti Complex, Tilak Road, Pune – 411002, Maharashtra, India Phone: +91 95453 60309 www.pilospray.com | www.myhealinghands.in

• World’s 1st plant-based touch-free spray treatment for Hemorrhoids (Piles) and Anal Fissure

Medical Management of Anorectal Diseases Revolutionized: Effective & Patient Friendly Approach

• India's 1st FDA-approved spray PiloSpray for the treatment of anorectal conditions • First-of-its-kind anorectal treatment kit, PiloKit with a spray for external application and tablets for oral consumption for the treatment of Hemorrhoids and Anal Fissure • Developed by Healing Hands & Herbs in collaboration with India's leading proctology hospital chain, Healing Hands Clinic • Clinically proven plant-based formulations, comprising the spray - PiloSpray and tablets - PiloTab and ConstiTab • Safety and efficacy scientifically validated at the molecular level in collaboration with the National Centre for Cell Science, a premier institute of the Government of India

Combination Treatment PiloSpray - Acts externally PiloTab -Treats Internally ConstiTab - Eases constipation Better Compliance Easy-to-use treatment protocol with one-of-its-kind combination of spray, tablet and a laxative tablet Lower Recurrence Early adoption, better compliance and effective treatment

Easy-to-use No applicator or direct touch involved in a difficult to reach affected area in the anal region Instant Relief Safe plant-based formulation for topical application for relief in pain. burning, itching, bleeding and inflammation, with a clinically proven action Better Patient Compliance Higher treatment compliance observed in patients who have used PiloSpray

www.pilospray.com | www.myhealinghands.in

PiloKit Indications: Treatment for Grade I & II Hemorrhoids (Piles) and Acute Anal Fissure

CLINICAL AND SCIENTIFIC PUBLICATIONS - Porwal A, Kundu GC, Bhagwat G and Butti R: Herbal medicine AnoSpray (PiloSpray) suppresses proinflammatory cytokines COX-2 and RANTES in the management of hemorrhoids, acute anal fissures and perineal wounds.

Exp Ther Med 23: 86, 2022 - Porwal A, Kundu GC, Bhagwat G and Butti R: Polyherbal formulation Anoac H (PiloTab) suppresses the expression of RANTES and VEGF for the management of bleeding hemorrhoids and fistula.

Mol Med Rep 24: 736, 2021 - Porwal Ashwin, Gandhi Paresh, Deepak Kulkarni. an open label, randomized, comparative, parallel group, single center study to evaluate safety and efficacy of AnoSpray (PiloSpray) in a comparison with betadine solution application in acute perineum wounds. ayush [Internet].

2018Apr.13 [cited 2022Aug.27];4(6):1409-12.

- Porwal Ashwin et al: A Prospective Open Label Interventional Clinical Study to Evaluate The Effects Of Constalax Powder (ConstiTab) In Constipation. International Ayurvedic Medical Journal {online} 2018 {cited April, 2018}

PiloKit: How to use & dosage PiloSpray:

• Spray continuously for 2 to 4 seconds from a distance of 5 to 8 cm away from the anal region • Apply 2 to 3 times in a day, preferably apply before and after motion and at night, or as many times depending upon the severity of the symptoms

PiloTab:

Take 1 tablet after breakfast and 1 tablet after dinner with water

ConstiTab:

Take 1 or 2 tablets after dinner with water, depending on the severity of constipation

Treatment Course of PiloKit:

Pilokit is a 15 days treatment course.

It can be repeated up to 6 times or 3 months depending on the severity of the symptoms of Hemorrhoids or Anal Fissure.

PiloSpray: 35 g Can PiloTab: 30 Tablets ConstiTab: 30 Tablets

www.pilospray.com | www.myhealinghands.in

Healing Hands & Herbs Pvt. Ltd. India

Certifications

Recognized by Government of India, Ministry of Commerce and Industry under Startup India

Developed in collaboration with • Asia’s Foremost Proctology Hospital • Centre for Excellence in Proctology • India’s only NABH Certified Proctology Hospital • A Chain of 20 Surgical Hospitals https://www.healinghandsclinic.co.in/

www.pilospray.com www.myhealinghands.in