Center for Breakthrough Medicines

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UNITE

DEVELOP

Your Trusted Partner for the Next Generation of Advanced Therapies

MANUFACTURE

BREAKTHROUGH

THE CBM DIFFERENCE

Capacity at Scale

Center for Breakthrough Medicines (CBM) is an advanced therapy

We offer turnkey expansion with modularly-designed and BLA-ready suites for high throughput and maximum yield.

patients that need them. Our end-to-end capabilities include plasmid

Single-Site CDMO

focused CDMO dedicated to delivering life-changing treatments to the DNA, viral vector manufacturing, and cell therapy production from

pre-clinical to commercial scale, with drug substance, drug product, and

analytical services all at a single site. Our team leaders were involved in

commercializing the first cell & gene therapies at leading biopharmas and CDMO’s, and are ready to help guide your innovations from concept to clinic to commercial.

Our capabilities are co-located on a single campus for seamless hand- off between development, manufacturing, and testing.

Expert Team & Partners Our leaders, hailing from top-tier CDMO’s and biopharmas, were involved with bringing the first cell and gene therapies to market, and our academic partners are pioneers in the field.

CAPABILITIES & CAPACITY AT A SINGLE-SITE

Flexible Ways of Working Viral Vector Suites

Cell Therapy Suites

Analytical Assays

We are willing to put skin in the game with flexible terms and milestone-based arrangements.

Integrated Analytical Capabilities THE ONLY FULLY INTEGRATED, END-TO-END PLATFORM

Cutting-edge analytical infrastructure and techniques enable us to rapidly get the critical answers around safety, efficacy, and potency.

FOR ADVANCED THERAPIES R&D

Process Development

Viral Vectors

Plasmid DNA

Cell Therapy

Cell Banking

Analytical Testing

Quality & Regulatory

Customizable Solutions www.breakthroughmedicines.com

Purpose-Built GMP Manufacturing Clinical and commercial GMP manufacturing with end-to-end capabilities from process development through drug substance manufacturing and drug product filling are supported with full testing capabilities.


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