Wholesale Natural Astaxanthin powder CAS 472-61-7

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

Natural Astaxanthin powder（472-61-7）Specifications Product Name

Natural Astaxanthin powder

Chemical Name

Ovoester; Astaxanthine; (3S,3'S)-Astaxanthin;3,3 ′ -dihydroxy- β , β -carotene-4,4′-dione

CAS Number

472-61-7

InChIKey

MQZIGYBFDRPAKN-SODZLZBXSA-N

Molecular Formula

C40H52O4

Molecular Weight

596.83848

Monoisotopic Mass

596.38656 g/mol

Melting Point

215-216 °C

Boiling Point

568.55°C (rough estimate)

Biological Half-Life

N/A

Color

pink to very dark purple

Solubility

DMSO: soluble1mg/mL (warmed)

Storage Temperature

−20°C

Application

Natural astaxanthin also known as astacin, is a kind of precious health ingredients, is used for development to enhance immunity, anti-oxidation, anti-inflammatory, eyes and brain health, regulating blood lipids and other natural and healthy products. At present, the main used as a raw material for human health food and medicine; aquaculture (currently the main salmon, trout and salmon), poultry feed additive and additives of cosmetics.

History of Astaxanthin It was in the 18th century that the algae Haematoccus pluvialis was discovered,

1

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

though it wasn ´t until the middle of the 20th century that the Astaxanthin that he produces was detected. In recent years, extensive research into its potential health benefits have been conducted and people have realized how powerful an antioxidant Astaxanthin really is. Every year around 100 new studies are done and by now approximately 1000 have already been published.

Astaxanthin is produced by the algae when they experience difficult environmental condition and stress. That can be due to a combination of things such a lack of food, absence of water, intense sunlight and change in temperature. As a result of the stress, the algae ´s cells have hyper accumulated the red pigment Astaxanthin, which serves as a “force-field” to protect them.

Types of Astaxanthin in the market There are two types of Astaxanthin; the natural form that is found in wild fish and algae and synthetic form made from petrochemicals. The natural Astaxanthin is much more powerful than the synthetic one, which only has ca. one-third of the antioxidant capacity of natural Astaxanthin. At Pure Natura, we of course use the freshwater algae Haematococcus Pluvialis. In addition to the Astaxanthin, the algae also contains a lot of omega-3 fatty acids. The algae is grown sustainably in Iceland and cultured using Iceland ´ s clean air, water and renewable power. Natural Astaxanthin powder will be provided by us and it is very popular in the market.

2

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

What is Natural Astaxanthin?

Astaxanthin is a naturally occurring carotenoid found in nature primarily in marine organisms such as microalgae, salmon, trout, krill, shrimp, crayfish, and crustaceans etc. Astaxanthin, dubbed the "king of the carotenoids" is red, and is responsible for turning salmon, crab, lobster and shrimp flesh pink. In crustaceans, it is surrounded by a protein and released by heat , this is why shrimp and lobsters turn red when cooked.

As a red-pink pigment, natural astaxanthin may also be found in the feathers of birds, such as quail, flamingo, and storks, as well as in propolis, the resinous substance collected by bees. And the green microalga Haematococcus pluvialis is considered the richest source of astaxanthin. Other microalgae, such as Chlorella zofingiensis, Chlorococcum spp., and Botryococcus braunii, also contain astaxanthin.

Besides,

some vegetables that feature a reddish color also has it.

For humans, natural astaxanthin is a lipid-soluble antioxidant carotenoid available to supplement through the intake of Haematococcus pluvialis-derived antioxidant products. Since astaxanthin could potentially improve indices of exercise metabolism, performance, and recovery because of its potent antioxidant capacity, so as a dietary supplement may be used for exercising humans, with broad health implications.

3

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

How Natural Astaxanthin Works?

Natural Astaxanthin is a powerful antioxidant. Antioxidants are an important nutrient to fight against free radical damage.

Free radicals are unpaired electrons that accumulate in cells as a byproduct of metabolism. And the immune system sometimes uses them to fight viruses and bacteria.

They also form when your dog is exposed to toxins such as: ▪ Chemicals ▪ Pesticides ▪ Processed foods ▪ Pollution ▪ Radiation

Once free radicals form in cells, their single electron makes them very unstable. So they react quickly with other compounds to capture a second electron. Once they have the second electron they become stable again.

And they often just attack the closest stable molecule and steal its electron. So the 4

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

damaged molecule with the missing electron becomes another free radical … and a chain reaction is set in motion.This process is called oxidative stress.

This is what causes damage to the cells, proteins, and DNA in your dog’s body. And it’s why free radicals are associated with common diseases including cancer, and premature aging.

The benefits of Natural Astaxanthin Natural astaxanthin have a good efffects on human, include:

- Astaxanthin Can Help Relieve Pain and Inflammation Natural Astaxanthin is a potent anti-inflammatory and pain reliever, blocking different chemicals in your body and reduces the inflammatory compounds that drive many chronic diseases, it can be used to treat rheumatoid arthritis (RA) and carpal tunnel syndrome etc diseases. Natural astaxanthin not only affects the COX 2 pathway, it suppresses serum levels of nitric oxide, interleukin 1B, prostaglandin E2, C Reactive Protein (CRP) and TNF-alpha (tumor necrosis factor alpha), and all of this has been proven ， of which natural astaxanthin was shown to reduce CRP by more than 20 percent in only eight weeks.

-Natural Astaxanthin Helps Fight Fatigue 5

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

Natural Astaxanthin have excellent recovery from exercise, it can help athletes do their best. Besides, Pure natural astaxanthin is indicated for recovery of muscles, better endurance, enhanced strength and improved energy levels.

- Natural Astaxanthin Supports Eye Health Natural Astaxanthin has the unique ability to cross through a barrier and reach your retina. Clinical trials have shown that astaxanthin helps diabetic retinopathy, macular degeneration, eye strain and fatigue and seeing in fine detail. Besides, natural Astaxanthin, it can improve damage in the center of the retina in people with AMD, but it does not improve damage in the outer areas of the retina.

- Natural Astaxanthin Cleans Up the Cells Natural Astaxanthin filters into every cell of the body. Its unique molecular lipophilic and hydrophilic properties allow it to span the entire cell, with one end of the astaxanthin molecule protecting the fat-soluble part of the cell and one end protecting the water-soluble part of the cell.

- Natural Astaxanthin Can protect Skin Astaxanthin has been shown to protect the body's largest organ, it reduce damage caused by ultraviolet radiation from the sun. Reserches show that taking astaxanthin by mouth for 9 weeks appears to reduce redness and loss of skin moisture caused by rays of the sun called "UV" rays.

thereby improving skin moisture levels, 6

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

smoothness, elasticity, fine wrinkles, and spots or freckles.

Besside, natural Astaxanthin also can be used for treating male infertility, menopausal symptoms, and reducing blood fats called triglycerides and increases high-density lipoprotein (HDL or "good") cholesterol in people with high cholesterol.

The use of Natural Astaxanthin Natural astaxanthin has a great health role in treating diseases. First, it is taken by mouth for treating Alzheimer's disease, Parkinson's disease, stroke, high cholesterol, liver diseases, age-related macular degeneration (age-related vision loss), and preventing cancer. Secondly, it is also used for metabolic syndrome, which is a group of conditions that increase the risk of heart disease, stroke and diabetes. Thirdly, it is also used for improving exercise performance, decreasing muscle damage after exercise, and decreasing muscle soreness after exercise. Also, astaxanthin is also taken to improve sleep, and for carpal tunnel syndrome, dyspepsia, male infertility, symptoms of menopause, and rheumatoid arthritis etc diseases.

At the same time, astaxanthin also plays its role in other fields. Such as in skin, astaxanthin is applied directly to the skin to protect against sunburn, to reduce wrinkles, and for other cosmetic benefits; In food, it may be used as a feed supplement and food coloring additive for salmon, crabs, shrimp, chicken, and egg 7

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

production; While in agriculture, astaxanthin is used as a food supplement for egg-producing chickens.

Reference: [1] Ambati, Ranga Rao; Phang, Siew-Moi; Ravi, Sarada; Aswathanarayana, Ravishankar Gokare (2014-01-07). "Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review". Marine Drugs. 12 (1): 128–152. doi:10.3390/md12010128. PMC 3917265. PMID 24402174.

[2] Choi, Seyoung; Koo, Sangho (2005). "Efficient Syntheses of the Keto-carotenoids Canthaxanthin, Astaxanthin, and Astacene". The Journal of Organic Chemistry. 70 (8): 3328–31. doi:10.1021/jo050101l. PMID 15823009.

[3] Summary of Color Additives for Use in the United States in Foods, Drugs, Cosmetics, and Medical Devices. Fda.gov. Retrieved on 2019-01-16.

[4] Lee SJ, Bai SK, Lee KS, Namkoong S, Na HJ, Ha KS, Han JA, Yim SV, Chang K, Kwon YG, Lee SK, Kim YM. Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation.

Mol Cells. 2003 Aug 31;16(1):97-105. PubMed PMID: 14503852.

8

Email: info@phcoker.com

Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

[5] Rüfer, Corinna E.; Moeseneder, Jutta; Briviba, Karlis; Rechkemmer, Gerhard; Bub, Achim (2008). "Bioavailability of astaxanthin stereoisomers from wild (Oncorhynchus spp.) and aquacultured (Salmo salar) salmon in healthy men: a randomised, double-blind study". The British Journal of Nutrition. 99 (5): 1048–54. doi:10.1017/s0007114507845521. ISSN 0007-1145. PMID 17967218.

[6] Yook JS et al., “Astaxanthin supplementation enhances adult hippocampal neurogenesis and spatial memory in mice,” Molecular Nutrition & Food Research, vol.

60, no. 3 (March 2016): 589–599.

9

Email: info@phcoker.com