Best SARM MK677 - What are the benefits of MK677

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Xuchang shangke Chemical Co., Ltd

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Raw Ibutamoren Mesylate (MK677) powder (159752-10-0) Specifications Product Name

Raw MK677 powder

Chemical Name

MK-677;2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-ind ole-3,4′-piperidin]-1′-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-met hylpropanamide methanesulfonate;

Brand Name

Ibutamoren Mesylate（MK677）

Drug Class

MK677 powder

CAS Number

159752-10-0

InChIKey

DUGMCDWNXXFHDE-VZYDHVRKSA-N

Molecular Formu C27H36N4O5S.CH4O3S la Molecular Weigh 624.768 g/mol t Monoisotopic Mass

624.229 g/mol

Melting Point

161 to 315ºC

Boiling Point

868.9 °c at 760 mmhg

Biological Half-Life

4-6 hours

Color

white to beige powder

Solubility

H2O: soluble5mg/mL, clear

Storage Tempera 2-8°C ture Ibutamoren Growth hormone releasing factor; alters metabolism of body fat; Mesylate Applica increase both muscle mass and bone mineral density; alters tion metabolism of body fat

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Phcoker

Xuchang shangke Chemical Co., Ltd

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MK677 Overview Raw Ibutamoren Mesylate (MK677) powder is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. MK-677 powder also alters metabolism of body fat and so may have application in the treatment of obesity.

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Phcoker

Xuchang shangke Chemical Co., Ltd

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Raw Ibutamoren Mesylate (MK677) powder ( 159752-10-0) Description Ibutamoren mesylate (also known as ibutamoren or MK677), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1).

Ibutamoren mesylate increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain.

GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition. Therefore, we can expect that ibutamoren mesylate may also affect these functions. However, so far, clinical studies describe only the effects ibutamoren mesylate has on appetite – and as expected, like ghrelin, ibutamoren mesylate increases it.

A great thing about ibutamoren mesylate is that it increases growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.

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Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

Raw Ibutamoren Mesylate (MK677) powder ( 159752-10-0) Mechanism of Action Ibutamoren mesylate (also known as ibutamoren or MK-677), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1).

Ibutamoren mesylate increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain.

GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition. Therefore, we can expect that ibutamoren mesylate may also affect these functions. However, so far, clinical studies describe only the effects ibutamoren mesylate has on appetite – and as expected, like ghrelin, ibutamoren mesylate increases it.

A great thing about ibutamoren mesylate is that it increases growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.

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Phcoker

Xuchang shangke Chemical Co., Ltd

www.phcoker.com

Benefits of Raw Ibutamoren Mesylate (MK677) powder ( 159752-10-0) ♦ MK677 May Help with Bone Density ♦ MK677 May Help Increase Muscle Growth ♦ MK677 May Help Decrease Muscle Wasting ♦ MK677 May Help with Sleep ♦ MK 677 May Reduce the Effects of Aging ♦ MK677 May Have Nootropic Effects on the Brain

Recommended MK677) powder (159752-10-0) Dosage Based on the research, 20 to 30mg seems to be the most optimal dosage.

There are reports of people taking more than 30mg of MK677 a day, but it did not yield in better results. What’s even more important than the dosage is the length of the cycle.

It’s extremely important that MK677 should be taken for a longer period of time. The growth hormone levels have to gradually build up in your body, which can take up to several weeks before you start feeling the effects.

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Phcoker

Xuchang shangke Chemical Co., Ltd

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Side effects of MK677 (159752-10-0) MK677 has not produced very many side effects for its users to be concerned about, but certain populations may have certain side effects to look out for.

Individuals who are vulnerable to insulin sensitivity or who have Diabetes may be at risk when taking MK677. Symptoms associated with these conditions could possibly be exacerbated by the use of MK677. Referring to a previously mentioned study, older individuals who had a previous heart condition are at a risk of heart failure when using MK677. In otherwise healthy individuals, there does not seem to be any harmful side effects that have been discovered, but further research is always needed to assure consumers of that.

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